ouabain has been researched along with verapamil in 244 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 148 (60.66) | 18.7374 |
| 1990's | 64 (26.23) | 18.2507 |
| 2000's | 20 (8.20) | 29.6817 |
| 2010's | 12 (4.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A | 1 |
| Lemaire, S; Mingeot-Leclercq, MP; Tulkens, PM; Van Bambeke, F | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bartolommei, G; Basilico, N; Brindisi, M; Brogi, S; Butini, S; Camodeca, C; Campiani, G; Fiorini, I; Gabellieri, E; Gemma, S; Gualdani, R; Habluetzel, A; Kukreja, G; Kunjir, S; Lamponi, S; Lucantoni, L; Martin, RE; Moncelli, MR; Novellino, E; Savini, L; Summers, RL; Tadini-Buoninsegni, F; Taramelli, D; Valoti, M | 1 |
| Anner, BM; Gervais, A; Lane, LK; Lindenmayer, GE; Schwartz, A | 1 |
| Aulbert, E; Ebel, H; Schurek, HJ | 1 |
| Hoeschen, RJ | 1 |
| Papadimituiou, JM; Sforcina, D | 1 |
| Schneider, JA; Sperelakis, N | 1 |
| Besch, HR; Watanabe, AM | 1 |
| Schirpke, B; Will, H; Wollenberger, A | 1 |
| Dunnet, J; Nayler, WG; Sullivan, A | 1 |
| Baum, SG; Fleischer, N; Kaneko, Y; Shapiro, S | 1 |
| Janssens, WJ; Vanhoutte, PM | 1 |
| Abe, Y; Aomine, M | 1 |
| Boschero, AC; Malaisse, WJ | 1 |
| McLean, MJ; Pelleg, A; Sperelakis, N | 1 |
| Dominguez, ML; Gonçalves, MJ; Ribeiro, JA | 1 |
| Chiba, S; Furukawa, Y; Kobayashi, M | 1 |
| Dunnett, J; Nayler, WG | 1 |
| Kelly, RJ; Klevans, LR | 1 |
| Karaki, H; Ozaki, H; Urakawa, N | 1 |
| Shuba, MF | 1 |
| Brobmann, GF; Mayer, M; Mikosch, H | 1 |
| Han, J; Tse, WW | 1 |
| Pasantes-Morales, H; Salceda, R | 1 |
| Nayler, WG | 1 |
| Foster, PR; King, RM; Nicoll, AB; Zipes, DP | 1 |
| Crevat, A; Gallice, P; Kovacic, H | 1 |
| Cortijo, J; Gonzalez, M; Morcillo, E; Ortiz, JL | 1 |
| Daniel, JC; Lecerf, JM; Levy, SB; Slapak, CA | 1 |
| Agata, N; Hara, Y; Hirano, S; Iguchi, H; Shirai, M; Tone, H; Urakawa, N | 1 |
| Hallaq, H; Leaf, A; Smith, TW | 1 |
| Aronson, RS; Goldberger, JJ | 1 |
| Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y; Yamazaki, M | 1 |
| Ji, GJ; Liu, DQ; Sheng, BH; Zhao, DH | 1 |
| Harada, K; Iwamoto, T; Nakajima, F; Sukamoto, T | 1 |
| Bikhazi, AB; el-Kasti, M; Medlej-Hashim, M | 1 |
| Goknur, AB; Haworth, RA | 1 |
| DeSantiago, J; Espinosa-Tanguma, R; Rasgado-Flores, H | 1 |
| Franz, DR; Robinson, CP | 1 |
| Pillai, G; Sutter, MC | 1 |
| Akabane, S; Ashida, T; Kawano, Y; Kuramochi, M; Omae, T; Yoshimi, H | 1 |
| Nakazato, Y; Satoh, E | 1 |
| Goknur, AB; Haworth, RA; Hunter, DR | 1 |
| Brodie, C; Sampson, SR | 1 |
| Bittar, EE; Nwoga, J | 3 |
| Aoki, K; Sato, K | 1 |
| Gorodetsky, R; Ramu, A; Ramu, N | 1 |
| Hamano, S; Morita, K; Oka, M; Yoshizumi, M | 1 |
| Miasiro, N; Paiva, AC | 1 |
| Bittar, EE; Huang, YP | 1 |
| Bose, D; Cragoe, EJ; Greenberg, AH; Kraut, RP | 1 |
| Brasch, H; Iven, H; von Poehl, C | 1 |
| Kindle, H; Kunkel, JG; Lanzrein, B | 1 |
| Abe, T; Maseki, T; Tomita, T | 1 |
| Davidson, M; Shanley, B; Wilce, P | 1 |
| Bassett, AL; Catstellanos, A; Furukawa, T; Kimura, S; Myerburg, RJ | 1 |
| Cole, WC; Dhalla, NS; Kolar, F; Ostadal, B | 1 |
| Reprintseva, VM | 1 |
| Kojima, M; Sperelakis, N | 1 |
| Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK | 1 |
| Kim, D; Smith, TW | 3 |
| Berkoff, HA; Goknur, AB; Haworth, RA; Hegge, JO; Hunter, DR | 1 |
| Karaki, H; Nagase, H; Ozaki, H; Urakawa, N | 1 |
| Lamb, FS; Myers, JH; Webb, RC | 1 |
| Aviv, A; Cragoe, E; Fine, BP; Hopp, L; Kino, M; Kuriyama, S; Nakamura, A | 1 |
| Amoroso, S; Annunziato, L; Di Renzo, GF; Kaparos, G; Maurano, F; Taglialatela, M | 1 |
| Claessens, MT; Ervasti, JM; Louis, CF; Mickelson, JR | 1 |
| Ishikawa, S; Saito, T | 1 |
| Bittar, EE; Xie, H | 1 |
| Dhein, S; Klaus, W; Müller, A | 1 |
| Neto, FR; Sperelakis, N | 1 |
| Bruyere, HJ; Nishikawa, T; Takagi, Y | 1 |
| Marín, J; Salaices, M; Sánchez-Ferrer, CF | 1 |
| Evans, DB; Harris, AL; Lemp, BM; Silver, PJ | 1 |
| Amoss, MS; Kile, JP | 1 |
| Lagerstrom, CF; McElroy, DD; Taegtmeyer, H; Walker, WE | 1 |
| Lamb, FS; Moreland, RS; Webb, RC | 1 |
| Karaki, H; Satoh, T | 1 |
| Hata, T; Makino, N; Nakanishi, H; Yanaga, T | 1 |
| Richardson, S; Twente, S | 1 |
| Matsumura, M; Shimizu, I | 1 |
| Nicholls, DG; Sanchez-Prieto, J; Sihra, TS | 1 |
| Hubel, KA; Renquist, KS | 1 |
| Iwasaki, A; Matsumura, M; Ohura, M; Saito, S; Shimizu, I; Yamonoi, A | 1 |
| Dhalla, NS; Tuana, BS | 1 |
| Boero, R; Deabate, MC; Forneris, G; Guarena, C; Piccoli, G; Quarello, F; Rosati, C | 1 |
| Ghosh, S; Liu, MS | 1 |
| Agbanyo, M; Bains, R; Hoeschen, RJ; Khatter, JC; Navaratnam, S | 1 |
| Shimada, T; Shimamura, K; Sunano, S; Tsuji, A | 1 |
| Iriuchijima, T; Wilber, JF | 1 |
| Goto, K; Miyamae, SI | 1 |
| Ibrahim, RH; Platt, JE | 1 |
| Bose, R; Lam, HY | 1 |
| Hoeschen, RJ; Khatter, JC; Navaratnam, S | 1 |
| Chiba, S; Katsuyama, Y; Tada, A; Tsukada, M; Zenda, H | 1 |
| Bush, LR; D'Alonzo, AJ; Evans, RM; Gaul, SL | 1 |
| McDonough, KH; Werchan, PM | 1 |
| Fang, DC; Jiang, MX; Xia, GJ; Yao, WX | 1 |
| Kobayashi, S; Suzuki, R; Yoshino, H | 1 |
| Chiba, S; Furukawa, Y; Saegusa, K | 1 |
| Gunst, SJ; Pisoni, JM | 1 |
| Takai, A; Tokuno, H; Tomita, T | 2 |
| Chappell, S; Henderson, A; Lewis, M | 1 |
| Chowdry, IH; Gomes, JA; Hariman, RJ; Kang, PS | 1 |
| Ahn, HY; Karaki, H; Nakagawa, H; Urakawa, N | 1 |
| Chappell, SP; Henderson, AH; Lewis, MJ | 1 |
| Powis, DA; Tan, CM | 1 |
| Dartt, DA; Donowitz, M; Joshi, VM; Rose, PE; Sharp, GW | 1 |
| Fairfax, CA; Tanz, RD | 1 |
| Lang, CH; McDonough, KH; Spitzer, JJ | 1 |
| Nakajyo, S; Shimizu, K; Urakawa, N | 1 |
| Baskin, SI; Franz, DB; Robinson, CP | 1 |
| Borda, E; Peredo, H | 1 |
| Kroeger, EA; Marshall, JM | 1 |
| Thyrum, PT | 1 |
| Hanna, C; Schmid, JR | 3 |
| Eto, S; Fleischer, N; Hutchins, M; Wood, JM | 1 |
| Couraud, F; Fayet, G; Lissitzky, S; Miranda, F | 1 |
| Evans, RW; Lindenmayer, GE; McCans, JL; Munson, RG; Schwartz, A | 1 |
| Gelband, H; Ilvento, JP; Merker, C; Rosen, MR | 1 |
| Kolassa, N; Pfleger, K; Volkmer, I | 1 |
| Singh, BN | 1 |
| Fischer, U; Haas, H; Raschack, M | 1 |
| Rodrigues-Pereira, E; Viana, AP | 1 |
| Dascal, N; Landau, EM; Lass, Y | 1 |
| Hayashi, S; Park, MK; Robotham, JL | 1 |
| Benabe, JE; Cruz-Soto, M; López-Novoa, JM; Martínez-Maldonado, M | 1 |
| Ohizumi, Y; Shibata, S | 1 |
| Bowles, BJ; Healy, TE; Pleuvry, BJ | 1 |
| Nagase, H; Ozaki, H; Tomono, J; Urakawa, N | 1 |
| Hubel, KA | 1 |
| Matsumura, M; Saito, S; Yamamoto, S; Yamanoi, A | 1 |
| Domboski, L; Krausz, Y; Phang, W; Sharp, GW | 1 |
| Burt, JM; Langer, GA | 1 |
| Cha, ZL; Fang, DC; Jiang, MX; Xia, GJ | 1 |
| Mas-Oliva, J; Nayler, WG; Williams, AJ | 1 |
| Bittar, EE; Mason-Sharp, D | 1 |
| Genest, J; Gutkowska, J; Lis, M; Schiffrin, EL | 1 |
| Arana, RM; Canga, L; Cossio, PM; Diez, C; Gimeno, AL; Sterin-Borda, L | 1 |
| Akerman, KE; Nicholls, DG | 1 |
| Barry, WH; Lorell, B; Marsh, JD; Smith, TW | 1 |
| Burt, JM | 1 |
| Shuttleworth, TJ | 1 |
| Briggs, RW; Osbakken, M | 1 |
| Abe, M; Furukawa, T | 1 |
| Abe, Y; Iwao, H; Mori, N; Okahara, T; Yamamoto, K; Yukimura, T | 1 |
| May, CN; Peart, WS | 1 |
| Taira, N; Yanagisawa, T | 1 |
| Fang, DC; Jiang, MX; Xia, GJ; Zha, ZL | 1 |
| Burgersdijk, C; van der Meer, FJ; van der Vijver, JC | 1 |
| Dannies, PS; Scammell, JG | 1 |
| Chiodini, PL; Phillips, RJ; Robinson, BF; Wilson, PN | 1 |
| Masahashi, T; Tomita, T | 1 |
| Chihara, S; Kishimoto, T; Ozaki, H; Umeno, H; Urakawa, N | 1 |
| Robinson, KR; Stump, RF | 1 |
| Bittar, EE; Helmer, P; Rusy, B | 1 |
| Christiansen, BD; Kjaer, K; Klitgaard, NA; Nielsen-Kudsk, F; Pedersen, KE | 1 |
| Aronson, RS; Hertzberg, J; Nusrat, A; Sonnenblick, EH; Tepper, D | 1 |
| Ito, K; Morita, T; Nose, T; Sukamoto, T; Yoshidomi, M | 1 |
| Aomine, M | 1 |
| Fray, JC; Han, DS; Park, CS | 1 |
| Janjic, D; Kikuchi, M; Sharp, GW; Siegel, EG; Wollheim, CB | 1 |
| Canga, L; Gimeno, AL; Sterin-Broda, L | 1 |
| Goldman, S; Morkin, E; Olajos, M | 1 |
| Kishimoto, T; Urakawa, N | 1 |
| Karaki, H; Kishimoto, T; Ozaki, H; Urakawa, N | 1 |
| Cohen, AJ; Fray, JC | 1 |
| Danilo, P; Rosen, MR | 1 |
| Pang, DC | 1 |
| Kishimoto, T; Ozaki, H; Urakawa, N | 1 |
| Karagueuzian, HS; Katzung, BG | 1 |
| Baskin, SI; Katz, TC; Kendrick, ZV; Orr, PL; Zaydon, PT | 1 |
| López-Novoa, JM; Martínez-Salgado, C; Ricote, M; Rodríguez-Barbero, A; Rodríguez-López, AM; Sancho, J | 1 |
| Haruno, A; Hashimoto, K | 1 |
| Hales, CA; Haupert, GT; Janssens, SP; Kachoris, C; Parker, WL | 1 |
| Fazekas, T; Gorgels, AP; Leunissen, JD; Vos, MA; Wellens, HJ | 1 |
| Blaustein, MP; Goldman, WF; Juhaszova, M; Krueger, BK; Yarowsky, PJ | 1 |
| Imanishi, S; Miyamae, S | 1 |
| Chen, YH; Tsai, MC | 1 |
| Bülow, A; Gustafsson, H; Nilsson, H | 1 |
| Belehradek, J; Garrigos, M; Mir, LM; Orlowski, S | 1 |
| Paterson, DJ; Ryan, DM | 1 |
| Elias, PM; Feingold, KR; Lee, SH; Mauro, T | 1 |
| Allen, JC; Kahn, AM; O'Neil, RG; Seidel, CL; Shelat, H; Song, T | 1 |
| Matlib, MA; Motley, ED; Paul, RJ | 1 |
| Geisler, A; Mørk, A | 1 |
| Fujita, T; Ito, Y | 1 |
| Baylen, BG; Cheung, J; Cyran, SE; Ditty, S; LaNoue, K; Phillips, J | 1 |
| De Clerck, F; Lu, HR; Remeysen, P | 1 |
| Conner, JA; Hernández-Cruz, A; Santi, CM | 1 |
| Bryant, HJ; Iwasa, KH; Kowtha, VC; Krauthamer, V; Stenger, DA | 1 |
| Dhalla, NS; Foerster, DR; Matsubara, T; Shah, KR; Xu, YJ | 1 |
| Abe, M; Arai, J; Asami, K; Kusunoki, S; Miyashita, Y; Moriya, T | 1 |
| Black, JL; Yang, KX | 1 |
| Breves, G; Pfeffer, E; Rittmann, I; Schröder, B | 1 |
| Miao, L; Morgan, JP; Perreault, CL; Travers, KE | 1 |
| Edwards, DH; Griffith, TM | 1 |
| Hedman, A; Meijer, DK | 2 |
| Kanj, NA; Nassar, CF; Samaha, M | 1 |
| Cozza, EN; Lantos, CP; Pecci, A; Romero, DG | 1 |
| Bäcker, A; Kramer, HJ; Meyer-Lehnert, H | 2 |
| Boucher, M; Chapuy, E; Chassaing, C; Lorente, P | 1 |
| Baysal, F; Ogülener, N; Onder, S; Yaktubay, N | 1 |
| Chen, ZL; Jiang, JH; Zheng, GH | 1 |
| Singh, B | 1 |
| Chiba, S; Furukawa, Y; Hirose, M; Kurogouchi, F; Nakajima, K; Tsuboi, M; Zhao, D | 1 |
| Doebler, JA | 1 |
| Fujino, T; Hara, M; Ishida, S; Ito, M; Iwao, T; Nakagawa, M; Ooie, T; Saikawa, T; Sakata, T; Takahashi, N; Yonemochi, H | 1 |
| Okorodudu, AO; Tarek Elghetany, M; Yang, H | 1 |
| Chowienczyk, PJ; Dawes, M; Delves, T; Dwivedi, R; Ritter, JM; Sieniawska, C | 1 |
| Bény, JL; Lamboley, M; Meister, JJ; Oishi, H; Schuster, A; Stergiopulos, N | 1 |
| Bondioli, KR; Bonk, AJ; Macháty, Z; Prather, RS; Ramsoondar, JJ | 1 |
| Ishii, T; Nishimura, M; Satoh, E | 1 |
| Küçukhüseyin, C; Oncel, H; Silan, C | 1 |
| HUQ, S; MELVILLE, KI; SHISTER, HE | 1 |
| Reyes, JL; Rosas-L, E; Villegas-Navarro, A | 1 |
| Cheng, L; Gong, XR; Wang, F; Yao, WX; Zhou, HY | 1 |
| Onur, R; Yenisehirli, A | 1 |
| Manju, L; Nair, RR | 1 |
| Daenas, C; Gourgoulianis, KI; Hatziefthimiou, AA; Molyvdas, PA | 1 |
| Tubek, S | 1 |
| Bishop, B; Conklin, DJ; Hargens, AR; Lillywhite, HB; Olson, KR | 1 |
| Baptista, BB; Farah, LS; Granado e Sá, M; Leite, VP; Zanotto, FP | 1 |
| Kalenda, DT; Morel, N; Ngombe, NK; Quetin-Leclercq, J | 1 |
| Lahnsteiner, F | 1 |
| Breves, G; Cehak, A; Feige, K; Guschlbauer, M; Mrochen, N; Schröder, B; Wilkens, MR | 1 |
| de Araújo Leite, JC; Marques-Santos, LF | 1 |
| Alexander, SP; Garle, MJ; Randall, MD; Roberts, RE; Wong, PS | 1 |
4 review(s) available for ouabain and verapamil
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
Drug-induced changes in the superficially located stores of calcium in heart sarcolemma.
Topics: Animals; Binding Sites; Blood Pressure; Bucladesine; Calcium; Dogs; Edetic Acid; Epinephrine; Guinea Pigs; Heart; Microscopy, Electron; Models, Biological; Myocardial Contraction; Myocardium; Ouabain; Rabbits; Sarcolemma; Sarcoplasmic Reticulum; Verapamil | 1976 |
Possibility of metabolic control of membrane excitation.
Topics: Animals; Biological Transport, Active; Calcium; Energy Metabolism; Glucose; Guinea Pigs; Hydroxybutyrates; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Sarcolemma; Sodium; Verapamil | 1985 |
Nuclear magnetic resonance: theory and review of cardiac applications.
Topics: Adenosine Triphosphate; Animals; Blood Circulation; Carbon Isotopes; Coronary Circulation; Coronary Disease; Heart; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Myocardium; Ouabain; Phosphorus; Propranolol; Verapamil | 1984 |
2 trial(s) available for ouabain and verapamil
| Article | Year |
|---|---|
Salt loads attenuate potassium-induced vasodilation of forearm vasculature in humans.
Topics: Adolescent; Adult; Blood Vessels; Diuretics; Female; Forearm; Humans; Male; Nitroprusside; Ouabain; Potassium; Potassium Chloride; Regional Blood Flow; Sodium Chloride; Vascular Resistance; Vasodilation; Verapamil | 1993 |
Barium reduces resting blood flow and inhibits potassium-induced vasodilation in the human forearm.
Topics: Adult; Barium; Blood Flow Velocity; Brachial Artery; Dose-Response Relationship, Drug; Enzyme Inhibitors; Forearm; Humans; Infusions, Intra-Arterial; Male; Nitroprusside; Norepinephrine; Ouabain; Plethysmography; Potassium; Vascular Resistance; Vasodilation; Vasodilator Agents; Verapamil | 2002 |
238 other study(ies) available for ouabain and verapamil
| Article | Year |
|---|---|
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors | 1980 |
Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells.
Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Daptomycin; Dogs; Humans; Kidney; Macrophages; Phagocytosis; Staphylococcus aureus | 2007 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents.
Topics: Animals; Antimalarials; Benzoxazines; Cell Line; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Mimicry; Quinazolines; Spectrometry, Mass, Electrospray Ionization | 2012 |
A possible molecular mechanism of the action of digitalis: ouabain action on calcium binding to sites associated with a purified sodium-potassium-activated adenosine triphosphatase from kidney.
Topics: Adenosine Triphosphatases; Adsorption; Animals; Binding Sites; Binding, Competitive; Calcium; In Vitro Techniques; Kidney; Kinetics; Lanthanum; Magnesium; Ouabain; Phospholipases; Phospholipids; Potassium; Prednisolone; Protein Denaturation; Sheep; Sodium; Verapamil | 1977 |
The effect of Ca ion antagonist verapamil on ouabain inhibition of renal sodium reabsorption. Studies in the isolated perfused rat kidney.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Biological Transport; Calcium; Glomerular Filtration Rate; Glucose; Hypoxia; Inulin; Kidney; Ouabain; Perfusion; Rats; Sodium; Urine; Verapamil | 1976 |
Effects of verapamil on (Na+ + K+)-ATPase, Ca2+-ATPase, and adenylate cyclase activity in a membrane fraction from rat and guinea pig ventricular muscle.
Topics: Adenosine Triphosphatases; Adenylyl Cyclases; Animals; Calcium; Guinea Pigs; Myocardium; Ouabain; Potassium; Rats; Sarcolemma; Sodium; Species Specificity; Verapamil | 1977 |
The effects of drugs on monocytic fusion in vivo.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Fusion; Cell Membrane; Cortisone; Cyclic AMP; Diphenhydramine; Edetic Acid; Glucagon; Insulin; Isoproterenol; Lidocaine; Lysosomes; Male; Mice; Mice, Inbred C57BL; Monocytes; Ouabain; Pyrilamine; Tetracaine; Trifluoperazine; Verapamil | 1975 |
Slow Ca2+ and Na+ responses induced by isoproterenol and methylxanthines in isolated perfused guinea pig hearts exposed to elevated K+.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Biological Transport; Bucladesine; Calcium; Guinea Pigs; Heart; Imidazoles; Isoproterenol; Lasalocid; Manganese; Myocardium; Ouabain; Perfusion; Potassium; Sodium; Time Factors; Verapamil; Xanthines | 1975 |
The relationship between adenosine 3',5'-monophosphate levels and systolic transmembrane calcium flux.
Topics: Animals; Biological Transport; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Ouabain; Papaverine; Potassium; Propranolol; Theophylline; Verapamil | 1975 |
Increased Ca2+ binding by a cardiac cell membrane preparation after cyclic AMP-enhanced intrinsic membrane protein phosphorylation.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cyclic AMP; Kinetics; Lanthanum; Muscle Proteins; Myocardium; Ouabain; Protein Binding; Protein Kinases; Receptors, Drug; Ruthenium Red; Sodium; Verapamil | 1976 |
The role of calcium in insulin release from hamster insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Calcium; Cricetinae; Cyclic AMP; Deoxyglucose; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mesocricetus; Ouabain; Potassium; Rats; Somatostatin; Verapamil | 1977 |
Instantaneous changes of alpha-adrenoceptor affinity caused by moderate cooling in canine cutaneous veins.
Topics: Animals; Biological Transport, Active; Body Temperature Regulation; Cold Temperature; Dogs; Estradiol; In Vitro Techniques; Muscle, Smooth; Norepinephrine; Ouabain; Pargyline; Phenoxybenzamine; Potassium; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Skin; Skin Temperature; Sodium; Vasomotor System; Veins; Verapamil | 1978 |
The relationship between contractile tension and intracellular cyclic AMP level in frog atrium: an analysis by using NaF, verapamil and ouabain.
Topics: Animals; Anura; Calcium; Cyclic AMP; In Vitro Techniques; Myocardial Contraction; Myocardium; Ouabain; Rana catesbeiana; Sodium Fluoride; Verapamil | 1978 |
Stimulus-secretion coupling of glucose-induced insulin release. XXIX. Regulation of 86Rb+ efflux from perfused islets.
Topics: Animals; Barium; Biological Transport, Active; Calcium; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Magnesium; Ouabain; Perfusion; Potassium; Rats; Rubidium; Tolbutamide; Valinomycin; Verapamil; Veratridine | 1979 |
Electrophysiological recordings from spontaneously contracting reaggregates of cultured smooth muscle cells from guinea pig vas deferens.
Topics: Action Potentials; Animals; Cells, Cultured; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Myofibrils; Ouabain; Tetrodotoxin; Vas Deferens; Verapamil | 1979 |
Purine effects at the neuromuscular junction and their modification by theophylline, imidazole and verapamil.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Female; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Junction; Norepinephrine; Ouabain; Purine Nucleosides; Purine Nucleotides; Rats; Theophylline; Verapamil | 1979 |
Effects of cardioactive substances on the post-stimulation potentiation of contractility in the isolated dog atrium.
Topics: Adenosine; Animals; Caffeine; Chlorides; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Manganese; Myocardial Contraction; Ouabain; Pentobarbital; Propranolol; Tetrodotoxin; Verapamil | 1978 |
Calcium efflux from cardiac sarcoplasmic reticulum: effects of calcium and magnesium.
Topics: Animals; Calcium; Guinea Pigs; Magnesium; Myocardium; Ouabain; Sarcoplasmic Reticulum; Verapamil | 1978 |
Effect of autonomic neural blockade on verapamil-induced suppression of the accelerated ventricular escape beat in ouabain-treated dogs.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Dogs; Female; Heart Rate; Male; Ouabain; Time Factors; Vagotomy; Verapamil | 1978 |
Possible role of Na-Ca exchange mechanism in the contractions induced in guinea-pig aorta by potassium free solution and ouabain.
Topics: Animals; Aorta, Thoracic; Calcium; Extracellular Space; Guinea Pigs; In Vitro Techniques; Male; Ouabain; Potassium; Sodium; Time Factors; Vasoconstriction; Verapamil | 1978 |
The effect of sodium-free and potassium-free solutions, ionic current inhibitors and ouabain on electrophysiological properties of smooth muscle of guinea-pig ureter.
Topics: Action Potentials; Animals; Guinea Pigs; In Vitro Techniques; Manganese; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Sodium; Tetraethylammonium Compounds; Ureter; Verapamil | 1977 |
[Glycoside induced intestinal ischemia. Therapeutic possibilities (author's transl)].
Topics: Animals; Blood Pressure; Cardiac Glycosides; Central Venous Pressure; Female; Heart Massage; Infarction; Intestines; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Ouabain; Regional Blood Flow; Strophanthins; Vascular Resistance; Verapamil | 1976 |
Effect of manganese chloride and Verapamil on automaticity of digitalized Purkinje fibers.
Topics: Animals; Calcium; Dogs; Heart Conduction System; Heart Ventricles; Manganese; Membrane Potentials; Ouabain; Purkinje Fibers; Verapamil | 1975 |
Calcium coupled release of [35S]taurine from retina.
Topics: Animals; Calcium; Chickens; Ionophores; Ouabain; Potassium; Retina; Sodium; Taurine; Verapamil | 1975 |
Some factors which influence the amount of calcium stored at the superficially located sites in cardiac muscle cells.
Topics: Animals; Binding Sites; Bromides; Calcium; Cell Membrane; In Vitro Techniques; Lanthanum; Myocardium; Nitrates; Ouabain; Rabbits; Time Factors; Verapamil | 1975 |
Suppression of ouabain-induced ventricular rhythms with aprindine HCl. A comparison with other antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Dogs; Indenes; Ouabain; Ventricular Fibrillation; Verapamil | 1976 |
Inhibition of sodium pump by bepridil. An in vitro and microcalorimetric study.
Topics: Adenosine Triphosphate; Bepridil; Diltiazem; Erythrocytes; Humans; Kinetics; Nicardipine; Nifedipine; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1992 |
Effects of low temperature and pharmacological interventions on the responses of the isolated guinea-pig trachea.
Topics: Amiloride; Animals; Cold Temperature; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Phorbol Esters; Protein Kinase C; Sodium-Potassium-Exchanging ATPase; Trachea; Verapamil | 1992 |
Energy-dependent accumulation of daunorubicin into subcellular compartments of human leukemia cells and cytoplasts.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Compartmentation; Chloroquine; Daunorubicin; Deoxyglucose; Dinitrophenols; Drug Interactions; Drug Resistance; Energy Metabolism; Ethylmaleimide; Humans; Leukemia; Membrane Glycoproteins; Methylamines; Microscopy, Fluorescence; Monensin; Ouabain; Sodium Azide; Tumor Cells, Cultured; Vanadates; Verapamil | 1992 |
A possible mechanism of endothelium-dependent relaxation induced by pirarubicin and carbachol in rat isolated aorta.
Topics: Amiloride; Animals; Aorta, Thoracic; Calcium; Carbachol; Choline; Doxorubicin; Endothelium, Vascular; In Vitro Techniques; Ion Exchange; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1992 |
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Fatty Acids, Unsaturated; Fish Oils; Heart; In Vitro Techniques; Ion Channel Gating; Myocardial Contraction; Nitrendipine; Ouabain; Rats; Verapamil | 1992 |
Effects of verapamil on ventricular tachycardia induced by ouabain in guinea pigs.
Topics: Animals; Calcium; Calcium Channels; Cardiac Pacing, Artificial; Electrocardiography; Guinea Pigs; Heart Block; Ouabain; Premedication; Tachycardia; Verapamil | 1992 |
Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes.
Topics: Animals; Chlorpromazine; Dipyridamole; Disopyramide; Drug Interactions; In Vitro Techniques; Lidocaine; Liver; Male; Nifedipine; Ouabain; Propranolol; Quinidine; Rats; Rats, Wistar; Sodium; Taurocholic Acid; Verapamil | 1992 |
[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Edetic Acid; Female; Guinea Pigs; Lidocaine; Male; Mice; Myocardial Reperfusion Injury; Onium Compounds; Ouabain; Rats; Rats, Inbred Strains; Ventricular Fibrillation; Verapamil | 1992 |
Effects of ouabain on muscle tension and intracellular Ca2+ level in guinea-pig aorta.
Topics: Animals; Aorta; Calcium; Carrier Proteins; Cell Membrane; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nickel; Ouabain; Quaternary Ammonium Compounds; Sodium Dodecyl Sulfate; Sodium-Calcium Exchanger; Verapamil | 1992 |
Effects of verapamil, ouabain, and ethacrynic acid on calcium retention in perfused rat kidneys.
Topics: Animals; Calcium; Calcium-Binding Proteins; Ethacrynic Acid; Female; Kidney; Kinetics; Ouabain; Perfusion; Rats; Rats, Sprague-Dawley; Sodium; Verapamil | 1992 |
Control of the Na-Ca exchanger in isolated heart cells. II. Beat-dependent activation in normal cells by intracellular calcium.
Topics: Animals; Biological Transport; Calcium; Calcium Channels; Carrier Proteins; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Myocardium; Ouabain; Potassium Chloride; Rats; Sarcolemma; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Tetrodotoxin; Verapamil | 1991 |
Stoichiometry and regulation of the Na-Ca exchanger in barnacle muscle cells.
Topics: Animals; Bumetanide; Calcium; Calcium Channels; Carrier Proteins; Chymotrypsin; Kinetics; Membrane Potentials; Muscles; Ouabain; Sodium; Sodium-Calcium Exchanger; Thoracica; Verapamil | 1991 |
Effects of palytoxin on guinea pig tracheal strips.
Topics: Acrylamides; Airway Resistance; Animals; Atropine; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Pyrilamine; Sodium; Solutions; Trachea; Verapamil | 1991 |
Effect of human plasma proteins on spontaneous contractile activity of rat mesenteric portal vein.
Topics: Alpha-Globulins; Animals; Atropine; Beta-Globulins; Blood Proteins; Chlorpheniramine; gamma-Globulins; Humans; Immunoglobulin G; Ketanserin; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Portal Vein; Rats; Rats, Inbred Strains; Saralasin; Serum Albumin; Verapamil | 1990 |
Effects of ouabain and verapamil on endothelin-1-induced contraction of mesenteric artery in young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Endothelins; Heart Rate; Hypertension; In Vitro Techniques; Isometric Contraction; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Verapamil | 1991 |
On the mechanism of ouabain-induced release of acetylcholine from synaptosomes.
Topics: Acetylcholine; Animals; Calcium; Extracellular Space; Female; Magnesium; Male; Membrane Potentials; Osmolar Concentration; Ouabain; Rats; Rats, Inbred Strains; Sodium; Synaptosomes; Tetrodotoxin; Verapamil | 1992 |
Evidence for the beat-dependent activation of the Na-Ca exchanger by intracellular Ca.
Topics: Animals; Calcium; Carrier Proteins; Electric Stimulation; Heart; Ouabain; Potassium Chloride; Rats; Sarcolemma; Sodium-Calcium Exchanger; Tetrodotoxin; Verapamil | 1991 |
Verapamil regulation of Na-K pump levels in rat skeletal myotubes: role of spontaneous activity and Na channels.
Topics: Action Potentials; Animals; Biological Transport, Active; Cycloheximide; Dactinomycin; Muscles; Ouabain; Potassium; Rats; Saxitoxin; Sodium; Sodium Channels; Verapamil | 1991 |
An investigation of the sensitivity of the ouabain-insensitive sodium efflux in single barnacle muscle fibers to pentachlorophenol.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Cobalt; Cytosol; Dihydropyridines; Egtazic Acid; Gallic Acid; Hydrogen-Ion Concentration; Kinetics; Muscles; Osmolar Concentration; Ouabain; Pentachlorophenol; Ryanodine; Sodium; Stimulation, Chemical; Thoracica; Verapamil | 1991 |
Early and late contraction induced by ouabain in human umbilical arteries.
Topics: Adult; Amiloride; Calcium; Calcium Channel Blockers; Egtazic Acid; Female; Humans; In Vitro Techniques; Monensin; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Pregnancy; Sarcoplasmic Reticulum; Sodium; Verapamil | 1991 |
Reduced ouabain-sensitive potassium entry as a possible mechanism of multidrug-resistance in P388 cells.
Topics: Animals; Cell Division; Cell Membrane; Drug Resistance; Leukemia P388; Membrane Potentials; Mice; Ouabain; Phenazines; Potassium; Tumor Cells, Cultured; Verapamil | 1991 |
Enhancement by cytochalasin B of ouabain-stimulated catecholamine secretion from cultured bovine adrenal chromaffin cells: possible relation to alteration in Na+/K(+)-pump activity.
Topics: Adrenal Medulla; Animals; Biological Transport, Active; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Cytochalasin B; Gallic Acid; Ouabain; Secretory Rate; Sodium-Potassium-Exchanging ATPase; Verapamil | 1990 |
Effects of endothelin-1 on the isolated guinea-pig ileum: role of Na+ ions.
Topics: Angiotensin II; Animals; Cyclic GMP; Drug Administration Schedule; Endothelins; Female; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Sodium; Verapamil | 1990 |
The behavior of the ouabain-insensitive sodium efflux in single barnacle muscle fibers toward the microinjection of aluminum.
Topics: Aluminum; Animals; Cadmium; Calcium; Deferoxamine; Egtazic Acid; Gallium; In Vitro Techniques; Magnesium; Microinjections; Muscles; Ouabain; Ryanodine; Scandium; Sodium; Thoracica; Verapamil | 1990 |
The influence of calcium, sodium, and the Na+/Ca2+ antiport on susceptibility to cytolysin/perforin-mediated cytolysis.
Topics: Amiloride; Animals; Barium; Biological Transport; Calcimycin; Calcium; Carrier Proteins; Cell Line; Cell Survival; Cytotoxicity, Immunologic; Cytotoxins; Killer Cells, Natural; Membrane Glycoproteins; Membrane Proteins; Mice; Ouabain; Perforin; Pore Forming Cytotoxic Proteins; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Strontium; Verapamil | 1990 |
Influence of N-ethylmaleimide on action potential and force of contraction of guinea-pig papillary muscles.
Topics: Action Potentials; Animals; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Papillary Muscles; Propranolol; Stimulation, Chemical; Tetrodotoxin; Verapamil | 1990 |
The effect of ions, ion channel blockers, and ionophores on uptake of vitellogenin into cockroach follicles.
Topics: Amiloride; Animals; Atropine; Calcium Channel Blockers; Cockroaches; Female; In Vitro Techniques; Ions; Ouabain; Ovarian Follicle; Tetraethylammonium Compounds; Valinomycin; Verapamil; Vitellogenins | 1990 |
Pharmacological properties of contraction caused by sodium removal in muscle strips isolated from canine coronary artery.
Topics: Amiloride; Animals; Arteries; Bepridil; Coronary Vessels; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Ouabain; Phentolamine; Potassium; Sodium; Verapamil | 1990 |
Ethanol and synaptosomal calcium homeostasis.
Topics: Animals; Brain; Caffeine; Calcium; Drug Interactions; Ethanol; Homeostasis; In Vitro Techniques; Lanthanum; Male; Ouabain; Potassium Cyanide; Rats; Rats, Inbred Strains; Synaptosomes; Verapamil | 1990 |
In vivo induction of "focal" triggered ventricular arrhythmias and responses to overdrive pacing in the canine heart.
Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Dogs; Electrophysiology; Female; Heart; Heart Ventricles; Male; Ouabain; Tachycardia; Verapamil | 1990 |
Transient inotropic effects of low extracellular sodium in perfused rat heart.
Topics: Amiloride; Animals; Azides; Calcium; Extracellular Space; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Ouabain; Rats; Rats, Inbred Strains; Ryanodine; Sodium; Sodium Azide; Time Factors; Verapamil | 1990 |
[Effect of Na+, K+ and Ca++ ions on catecholamine release in the caudal mesenteric ganglion].
Topics: Acetylcholine; Animals; Calcium; Dogs; Epinephrine; Female; Ganglia, Sympathetic; In Vitro Techniques; Ion Channels; Male; Norepinephrine; Ouabain; Potassium; Sodium; Splanchnic Nerves; Verapamil | 1985 |
Effects of calcium channel blockers on ouabain-induced oscillatory afterpotentials in organ-cultured young embryonic chick hearts.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Bepridil; Calcium Channel Blockers; Chick Embryo; Diltiazem; Ion Channels; Nifedipine; Organ Culture Techniques; Ouabain; Pyrrolidines; Verapamil | 1986 |
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil | 1986 |
Inhibition of multiple trans-sarcolemmal cation flux pathways by dichlorobenzamil in cultured chick heart cells.
Topics: Amiloride; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Chick Embryo; Ion Channels; Myocardial Contraction; Myocardium; Ouabain; Potassium Radioisotopes; Sarcolemma; Sodium; Sodium Radioisotopes; Verapamil | 1986 |
Control of thallium and sodium fluxes in isolated adult rat heart cells by anthopleurin-A, verapamil and magnesium.
Topics: Animals; Edetic Acid; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Ion Channels; Kinetics; Magnesium; Myocardium; Ouabain; Peptides; Potassium; Rats; Sodium; Thallium; Verapamil | 1986 |
Effects of palytoxin on contractile response and calcium movement in guinea-pig taenia coli.
Topics: Acrylamides; Adenosine Triphosphate; Animals; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Muscle Contraction; Ouabain; Potassium; Saponins; Sodium; Verapamil | 1987 |
Contractile responses to ouabain and potassium-free solution in vascular tissue from renal hypertensive rats.
Topics: Animals; Buffers; Calcium; Hypertension, Renal; Ion Channels; Isotonic Solutions; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1987 |
Angiotensin II effect on 22Na+ transport in vascular smooth muscle cells.
Topics: Amiloride; Angiotensin II; Animals; Cells, Cultured; Drug Interactions; Male; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred Strains; Sodium; Sodium Radioisotopes; Verapamil | 1988 |
Membrane events and ionic processes involved in dopamine release from tuberoinfundibular neurons. I. Effect of the inhibition of the Na+,K+-adenosine triphosphatase pump by ouabain.
Topics: Animals; Calcium; Dopamine; Doxorubicin; Female; Hypothalamus; In Vitro Techniques; Ion Channels; Membranes; Neurons; Nomifensine; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin; Tritium; Verapamil | 1988 |
Altered transverse tubule dihydropyridine receptor binding in malignant hyperthermia.
Topics: Adenosine Triphosphatases; Animals; Calcium Channels; Kinetics; Malignant Hyperthermia; Muscles; Nitrendipine; Organelles; Ouabain; Receptors, Nicotinic; Reference Values; Sodium-Potassium-Exchanging ATPase; Swine; Swine Diseases; Verapamil | 1989 |
Effect of ouabain on cellular free calcium and cellular cyclic AMP production in response to arginine vasopressin in rat renal papillary collecting tubule cells in culture.
Topics: Animals; Arginine Vasopressin; Calcium; Calmodulin; Cells, Cultured; Cyclic AMP; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Male; Ouabain; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Nicardipine as a Ca2+ channel blocker in single barnacle muscle fibers.
Topics: Animals; Calcium Channels; Hydrogen-Ion Concentration; Muscles; Nicardipine; Ouabain; Potassium; Sodium; Thoracica; Verapamil | 1989 |
The potential of epicardial activation mapping in isolated hearts for the assessment of arrhythmogenic and antiarrhythmic drug activity.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Heart; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Ouabain; Rabbits; Verapamil | 1989 |
Analysis of the hyperpolarizing effect of catecholamines on canine cardiac Purkinje fibres.
Topics: Animals; Barium; Catecholamines; Cesium; Dinitrophenols; Dogs; Epinephrine; Heart; Heart Conduction System; In Vitro Techniques; Isoproterenol; Membrane Potentials; Norepinephrine; Ouabain; Potassium; Purkinje Fibers; Sodium; Verapamil | 1989 |
Protective effect of ouabain on adriamycin-induced cardiovascular anomalies in chick embryos.
Topics: Animals; Chick Embryo; Coenzymes; Dose-Response Relationship, Drug; Doxorubicin; Heart; Heart Defects, Congenital; Morphogenesis; Ouabain; Ubiquinone; Verapamil; Vitamin E | 1989 |
Effects of ouabain on isolated cerebral and femoral arteries of the cat: a functional and biochemical study.
Topics: Animals; Binding, Competitive; Cats; Cerebral Arteries; Female; Femoral Artery; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Verapamil | 1988 |
The vasorelaxant effects of milrinone and other vasodilators are attenuated by ouabain.
Topics: Animals; Aorta, Thoracic; Colforsin; Drug Interactions; Female; Guinea Pigs; Hydralazine; In Vitro Techniques; Isoproterenol; Isoquinolines; Isosorbide; Milrinone; Nitroprusside; Ouabain; Pyridones; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Vasodilator Agents; Verapamil | 1988 |
Role of Ca2+ and Na+ on luteinizing hormone release from the calf pituitary.
Topics: Animals; Calcimycin; Calcium; Calcium Channels; Cattle; Cobalt; Female; In Vitro Techniques; Kinetics; Luteinizing Hormone; Magnesium; Male; Nifedipine; Ouabain; Pituitary Gland, Anterior; Sodium; Tetrodotoxin; Verapamil | 1988 |
Improved recovery of cardiac function after hypothermic ischemic storage with ouabain.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Glycogen; Heart; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Organ Preservation; Ouabain; Phosphocreatine; Rabbits; Sodium-Potassium-Exchanging ATPase; Verapamil | 1988 |
Calcium and contractile responses to ouabain and potassium-free solution in aortae from spontaneously hypertensive rats.
Topics: Animals; Aorta; Calcium; Calcium Channels; Egtazic Acid; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Verapamil | 1988 |
Release of prostaglandins during the contraction of rat aorta induced by ouabain and K+-free solution.
Topics: Animals; Aorta, Thoracic; Calcium; In Vitro Techniques; Indomethacin; Ion Exchange; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Prostaglandins; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1988 |
Modulation of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles by Ca2+ antagonists.
Topics: Adenosine Triphosphate; Alamethicin; Animals; Calcium; Calcium Channel Blockers; Digitoxigenin; Diltiazem; Dogs; Monensin; Nifedipine; Ouabain; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1988 |
Mouse hypothalamic somatostatin release: roles of calcium and calmodulin.
Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calmodulin; Egtazic Acid; Hypothalamus; Male; Mice; Ouabain; p-Methoxy-N-methylphenethylamine; Potassium Chloride; Somatostatin; Sulfonamides; Verapamil; Veratridine | 1985 |
[In vivo and in vitro effects of bradykinin on the release of beta-endorphin-like immunoreactivity].
Topics: Animals; beta-Endorphin; Bradykinin; Calcium; Endorphins; In Vitro Techniques; Male; Ouabain; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Stimulation, Chemical; Verapamil | 1985 |
Characterization of the exocytotic release of glutamate from guinea-pig cerebral cortical synaptosomes.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cerebral Cortex; Energy Metabolism; Ethers; Exocytosis; Glutamates; Glutamic Acid; Guinea Pigs; Hydrogen-Ion Concentration; Ionomycin; Ouabain; Synaptosomes; Verapamil; Veratridine | 1987 |
The neurosecretory effect of ouabain on isolated rabbit ileal mucosa.
Topics: Animals; Atropine; Biological Transport; Calcium; Chlorides; Electric Conductivity; Ileum; Intestinal Mucosa; Kinetics; Neurotransmitter Agents; Ouabain; Rabbits; Sodium; Tetrodotoxin; Verapamil | 1988 |
In vivo and in vitro effects of bradykinin on the release of beta-endorphin-like immunoreactivity.
Topics: Animals; beta-Endorphin; Bradykinin; Calcium; Dexamethasone; Endorphins; In Vitro Techniques; Male; Ouabain; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Inbred Strains; Verapamil | 1985 |
Solubilization of a divalent cation dependent ATPase from dog heart sarcolemma.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cations, Divalent; Chromatography, Gel; Chromatography, Ion Exchange; Dogs; Heart Ventricles; Kinetics; Magnesium; Myocardium; Oligomycins; Ouabain; Sarcolemma; Solubility; Vanadates; Verapamil | 1987 |
In vitro effects of verapamil and methoxy-verapamil [D 600] on transmembrane sodium and potassium transport in human erythrocytes.
Topics: Biological Transport, Active; Bumetanide; Erythrocytes; Gallopamil; Humans; In Vitro Techniques; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1985 |
Myocardial sodium pump activity in endotoxin shock.
Topics: Animals; Calcium; Dogs; Female; Male; Myocardium; Ouabain; Phosphorylation; Rubidium; Shock, Septic; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1986 |
Digitalis-induced mechanical toxicity: protection by slow Ca++ channel blockers.
Topics: Animals; Calcium Channel Blockers; Cardiac Glycosides; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Ventricles; Nifedipine; Ouabain; Perfusion; Sodium-Potassium-Exchanging ATPase; Strophanthidin; Verapamil | 1986 |
Comparison of contractile effects of sodium vanadate and ouabain in vascular smooth muscles of guinea-pigs and rats.
Topics: Animals; Aorta; Basilar Artery; Guinea Pigs; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Vanadates; Vanadium; Verapamil | 1986 |
Thyrotropin-releasing hormone and histidyl-proline diketopiperazine: stimulation of secretion from hypothalamic fragments in vitro by depolarizing agents.
Topics: Animals; Egtazic Acid; Hypothalamus; In Vitro Techniques; Kinetics; Male; Ouabain; Peptides, Cyclic; Piperazines; Potassium Chloride; Rats; Rats, Inbred Strains; Tetrodotoxin; Thyrotropin-Releasing Hormone; Verapamil; Veratridine | 1987 |
Effects of ethylene glycol-bis-(beta-aminoethyl ether)-N,N'-tetraacetic acid on rabbit sinoatrial node cells treated with cardiotonic steroids.
Topics: Action Potentials; Animals; Calcium; Cardiotonic Agents; Egtazic Acid; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Lithium; Male; Membrane Potentials; Nifedipine; Ouabain; Rabbits; Sinoatrial Node; Sodium; Strontium; Tetrodotoxin; Verapamil | 1988 |
Enhancement of ornithine decarboxylase activity in Ambystoma liver slices by ovine prolactin: an evaluation of possible mediators.
Topics: Ambystoma; Animals; Calcimycin; Diglycerides; In Vitro Techniques; Larva; Liver; Ornithine Decarboxylase; Ouabain; Oxytocin; Prolactin; Verapamil | 1988 |
Membrane transport changes in an adriamycin-resistant murine leukemia cell line and in its sensitive parental cell line.
Topics: Animals; Biological Transport; Cell Membrane; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Ouabain; Rubidium; Sodium; Tumor Cells, Cultured; Verapamil | 1988 |
Protective effect of verapamil upon ouabain-induced cardiac arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Ouabain; Verapamil | 1988 |
Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.
Topics: Animals; Arteries; Blood Proteins; Cardenolides; Digoxin; Dogs; Ear, External; Epinephrine; Humans; Hypertension; In Vitro Techniques; Mesenteric Arteries; Ouabain; Phentolamine; Potassium Chloride; Quinazolines; Saponins; Vasoconstrictor Agents; Verapamil | 1987 |
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Felodipine; Female; Male; Nitrendipine; Ouabain; Verapamil | 1987 |
The right ventricular working heart preparation.
Topics: Animals; Blood Pressure; Calcium; Coronary Circulation; Heart; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Physiology; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Studies on the calcium antagonistic action of tetrandrine: XIV. Influence of tetrandrine and verapamil on hemodynamic action of ouabain in guinea pigs.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzylisoquinolines; Calcium Channel Blockers; Guinea Pigs; Hemodynamics; Myocardial Contraction; Ouabain; Stimulation, Chemical; Verapamil | 1987 |
Effects of amiloride and ouabain on contractile state, Ca and Na fluxes, and Na content in cultured chick heart cells.
Topics: Amiloride; Animals; Calcium; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Myocardial Contraction; Myocardium; Ouabain; Sodium; Tetrodotoxin; Time Factors; Verapamil | 1986 |
[Divalent chelating agents, calcium blockers and metabolic inhibitors had different effects on the iris sphincter muscles].
Topics: Animals; Barium; Calcium Channel Blockers; Cattle; Chelating Agents; Iodoacetates; Iodoacetic Acid; Iris; Muscle Contraction; Muscle, Smooth; Ouabain; Sodium Fluoride; Verapamil | 1986 |
Ouabain-induced negative frequency-force relationship in the isolated, blood-perfused dog atrium.
Topics: Animals; Atrial Function; Blood; Calcium Chloride; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes; In Vitro Techniques; Injections; Myocardial Contraction; Ouabain; Perfusion; Verapamil | 1986 |
Effects of extracellular calcium on canine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Dogs; Extracellular Space; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Serotonin; Trachea; Verapamil | 1986 |
Effect of growth in low-Na+ medium on transport sites in cultured heart cells.
Topics: Animals; Biological Transport, Active; Cell Count; Cell Division; Cells, Cultured; Chick Embryo; Culture Media; Kinetics; Myocardial Contraction; Myocardium; Ouabain; Potassium; Sodium; Tetrodotoxin; Time Factors; Verapamil | 1986 |
Characterization of the mechanical behavior of isolated papillary muscle preparations of the ferret.
Topics: Animals; Caffeine; Calcium; Ferrets; Heart; In Vitro Techniques; Isometric Contraction; Isotonic Contraction; Male; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption; Papillary Muscles; Species Specificity; Temperature; Verapamil | 1986 |
Sustained symptomatic sinus node reentrant tachycardia: incidence, clinical significance, electrophysiologic observations and the effects of antiarrhythmic agents.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Electrophysiology; Humans; Male; Middle Aged; Ouabain; Propranolol; Sinoatrial Node; Tachycardia; Tachycardia, Paroxysmal; Time Factors; Verapamil | 1985 |
Increase in membrane permeability in the absence of Ca and Mg in the smooth muscle of guinea-pig taenia coli.
Topics: Animals; Calcium; Cell Membrane Permeability; Colon; Guinea Pigs; In Vitro Techniques; Lithium; Magnesium; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Sodium; Time Factors; Verapamil | 1985 |
Myocardial reoxygenation damage: can it be circumvented?
Topics: Animals; Calcium; Cats; Diltiazem; Heart; Hypoxia; In Vitro Techniques; Lidoflazine; Myocardial Contraction; Myocardium; Ouabain; Oxygen; Papillary Muscles; Perfusion; Rabbits; Stimulation, Chemical; Verapamil | 1985 |
Cardiac glycosides, calcium and the release of neurotransmitter from peripheral noradrenergic nerves.
Topics: Animals; Calcium; Cardiac Glycosides; Dogs; In Vitro Techniques; Norepinephrine; Ouabain; Perfusion; Potassium; Saphenous Vein; Strophanthidin; Sympathetic Nervous System; Verapamil | 1985 |
Role of calcium in cholinergic stimulation of lacrimal gland protein secretion.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Eye Proteins; Gallic Acid; Intracellular Membranes; Lacrimal Apparatus; Male; Ouabain; Parasympathetic Nervous System; Peroxidases; Rats; Rats, Inbred Strains; Sulfonamides; Verapamil | 1985 |
Insurmountable antagonism of ouabain-induced coronary constriction by prazosin.
Topics: Animals; Coronary Vessels; In Vitro Techniques; Ouabain; Prazosin; Quinazolines; Swine; Vasoconstriction; Verapamil | 1985 |
Effects of readmission of substrate on the membrane potential in glycogen-depleted guinea-pig taenia coli.
Topics: 3-Hydroxybutyric Acid; Animals; Calcium; Carbachol; Colon; Glucose; Glycogen; Guinea Pigs; Hot Temperature; Hydroxybutyrates; In Vitro Techniques; Membrane Potentials; Muscle, Smooth; Ouabain; Potassium; Verapamil | 1985 |
Effect of cardiotropic agents on the myocardial dysfunction of hyperdynamic sepsis.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Cardiovascular Agents; Heart; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Rats; Rats, Inbred Strains; Sepsis; Tetracaine; Verapamil | 1985 |
Species differences in the inhibitory effect of ouabain on high K-induced contraction in the ileal longitudinal muscle.
Topics: Animals; Dogs; Guinea Pigs; Ileum; In Vitro Techniques; Macaca fascicularis; Mice; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Rabbits; Rats; Sodium; Species Specificity; Verapamil | 1985 |
The mechanisms of action of cyanide on the rabbit aorta.
Topics: Animals; Aorta, Thoracic; Cyanides; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Potassium; Rabbits; Verapamil | 1985 |
The effects of norepinephrine and acetylcholine in the vas deferens from normal and diabetic rats: influence of ouabain and verapamil.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Vas Deferens; Verapamil | 1985 |
Adrenergic influences on uterine smooth muscle.
Topics: Animals; Butyrates; Calcium; Chlorides; Cyclic AMP; Female; In Vitro Techniques; Isoproterenol; Lanthanum; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ouabain; Papaverine; Potassium; Pregnancy; Propranolol; Rats; Receptors, Adrenergic; Temperature; Uterus; Verapamil | 1973 |
Inotropic stimuli and systolic transmembrane calcium flow in depolarized guinea-pig atria.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Edetic Acid; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Membrane Potentials; Ouabain; Potassium; Quinidine; Stimulation, Chemical; Temperature; Time Factors; Verapamil | 1974 |
Antiarrhythmic actions of a new coronary vasodilator agent, iproveratril.
Topics: Aconitum; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Epinephrine; Humans; Ouabain; Vasodilator Agents; Verapamil | 1967 |
Pituitary 45 Ca ion uptake and release of ACTH, GH, and TSH: effect of verapamil.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Calcium Radioisotopes; Cyclic AMP; Depression, Chemical; Growth Hormone; Hypothalamus; In Vitro Techniques; Male; Ouabain; Pituitary Gland; Potassium; Rats; Theophylline; Thyrotropin; Thyrotropin-Releasing Hormone; Tissue Extracts; Vasopressins; Verapamil | 1974 |
Electro-optical system for monitoring activity of heart cells in culture: application to the study of several drugs and scorpion toxins.
Topics: Acetylcholine; Animals; Bucladesine; Calcium; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Electrophysiology; Epinephrine; Heart; Heart Rate; Isoproterenol; Methods; Myocardium; Norepinephrine; Ouabain; Propranolol; Reserpine; Scorpions; Tetrodotoxin; Toxins, Biological; Trypsin; Tubocurarine; Verapamil | 1974 |
A comparison of the antiarrhythmic actions of two new synthetic compounds, iproveratril and MJ 1999, with quinidine and pronethalol.
Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Vessels; Dogs; Electrocardiography; Epinephrine; Ethanolamines; Female; Heart Rate; Male; Ouabain; Quinidine; Tachycardia; Verapamil | 1967 |
A dissociation of positive staircase (Bowditch) from ouabain-induced positive inotropism.
Topics: Animals; Calcium; Heart; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Myocardium; Ouabain; Perfusion; Rabbits; Sodium; Time Factors; Verapamil | 1974 |
Effects of verapamil on electrophysiologic properties of canine cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Calcium; Dogs; Heart Conduction System; Manganese; Membrane Potentials; Neural Conduction; Ouabain; Potassium; Refractory Period, Electrophysiological; Verapamil | 1974 |
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances].
Topics: Alkaloids; Allopurinol; Animals; Carbon Isotopes; Cocaine; Depression, Chemical; Dipyridamole; Drug Synergism; Ethylenediamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardium; Nitroglycerin; Nucleosides; Ouabain; Papaverine; Prenylamine; Probenecid; Pyridines; Reserpine; Stimulation, Chemical; Theophylline; Triamterene; Vasodilator Agents; Verapamil | 1969 |
A fourth class of anti-dysrhythmic action? Effect of verapamil on ouabain toxicity, on atrial and ventricular intracellular potentials, and on other features of cardiac function.
Topics: Action Potentials; Anesthesia, Local; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmias, Cardiac; Calcium; Electric Conductivity; Electrocardiography; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Myocardium; Ouabain; Rabbits; Sciatic Nerve; Verapamil | 1972 |
[Study of combinations of verapamil and quinidine].
Topics: Aconitum; Animals; Arrhythmias, Cardiac; Dogs; Drug Synergism; Electrocardiography; Guinea Pigs; Heart; Ouabain; Pacemaker, Artificial; Quinidine; Verapamil | 1971 |
Antiarrhythmic actions of coronary vasodilator agents papaverine, dioxyline and verapamil.
Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Epinephrine; Female; Heart Atria; Heart Ventricles; Hydrocarbons; Isoquinolines; Male; Nitriles; Ouabain; Papaverine; Quinidine; Tachycardia; Vasodilator Agents; Verapamil | 1970 |
The actions of verapamil on experimental arrhythmias.
Topics: Acetylcholine; Aconitum; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmias, Cardiac; Blood Pressure; Depression, Chemical; Dogs; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Nitriles; Ouabain; Rabbits; Vasodilator Agents; Verapamil | 1968 |
Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'-cyclic monophosphate.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Cell Membrane Permeability; Chlorides; Cyclic GMP; Female; In Vitro Techniques; Membrane Potentials; Oocytes; Ouabain; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Verapamil; Xenopus laevis | 1984 |
Cooling-induced contraction of guinea pig tracheal smooth muscle.
Topics: Animals; Bicarbonates; Cold Temperature; Female; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Ouabain; Potassium Chloride; Sodium Bicarbonate; Sodium-Potassium-Exchanging ATPase; Solutions; Trachea; Verapamil | 1984 |
Na+-K+-ATPase inhibitors and renin release: relationship to calcium.
Topics: Animals; Blood Pressure; Calcium; Dogs; Female; Glomerular Filtration Rate; Heart Rate; Ion Channels; Kidney; Kinetics; Male; Natriuresis; Ouabain; Renal Circulation; Renin; Sodium-Potassium-Exchanging ATPase; Vanadates; Vanadium; Verapamil | 1984 |
Nature of anthopleurin-B-induced release of norepinephrine from adrenergic nerves.
Topics: Adrenergic Fibers; Animals; Cnidaria; Gallopamil; Guanethidine; Guinea Pigs; Intercellular Signaling Peptides and Proteins; Kinetics; Male; Norepinephrine; Ouabain; Peptides; Potassium; Sea Anemones; Tetrodotoxin; Vas Deferens; Verapamil | 1982 |
The effect on the rat isolated atria of amiodarone in the presence of either ouabain or verapamil.
Topics: Amiodarone; Animals; Benzofurans; Drug Interactions; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Rats; Rats, Inbred Strains; Verapamil | 1983 |
The mechanism of contractile action of palytoxin on vascular smooth muscle of guinea-pig aorta.
Topics: Acrylamides; Animals; Aorta; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Potassium; Sodium; Verapamil | 1983 |
Sensitivity to injected cholera toxin of the sodium efflux in single barnacle muscle fibers.
Topics: Adenylyl Cyclases; Animals; Cadmium; Calcium; Calmodulin; Carrier Proteins; Cholera Toxin; Edetic Acid; Egtazic Acid; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ion Channels; Iron; Magnesium; Membranes; Muscles; NAD; Ouabain; Sodium; Thoracica; Verapamil; Zinc | 1984 |
Chymotrypsin, ileal chloride transport, and neurotransmitters.
Topics: Animals; Chlorides; Chymotrypsin; Dinoprostone; Electric Stimulation; Ileum; Intestinal Mucosa; Ion Channels; Neurotransmitter Agents; Ouabain; Prostaglandins E; Rabbits; Theophylline; Trifluoperazine; Vasoactive Intestinal Peptide; Verapamil | 1984 |
In vivo and in vitro effects of substance P on the release of beta-endorphin-like immunoreactivity.
Topics: Animals; beta-Endorphin; Calcium; Culture Techniques; Dose-Response Relationship, Drug; Endorphins; Male; Ouabain; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains; Substance P; Verapamil | 1982 |
Mechanisms of synergism between glucose and cAMP on stimulation of insulin release.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biomechanical Phenomena; Calcium; Carbachol; Choline; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Glucose; Insulin; Ion Exchange; Islets of Langerhans; Isotonic Solutions; Male; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Ringer's Solution; Sodium; Stimulation, Chemical; Verapamil | 1984 |
Ca++ distribution after Na+ pump inhibition in cultured neonatal rat myocardial cells.
Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Biological Transport, Active; Calcium; Cells, Cultured; Fibroblasts; Lanthanum; Myocardium; Ouabain; Potassium; Rats; Sodium; Verapamil | 1982 |
[Antagonistic effects of tetrandrine on ouabain-induced contraction of coronary arterial strips].
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Coronary Vessels; In Vitro Techniques; Ouabain; Swine; Vasoconstriction; Verapamil | 1983 |
Sarcolemmal calcium transport and drug action.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Biological Transport; Calcium; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Magnesium; Ouabain; Rabbits; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Verapamil | 1980 |
Stimulation by high external potassium of the sodium efflux in barnacle muscle fibers.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Calcium; Chelating Agents; Ion Channels; Magnesium; Muscles; Nucleotides, Cyclic; Ouabain; Potassium; Protein Kinase Inhibitors; Sodium; Thoracica; Verapamil | 1981 |
Role of Ca2+ in response of adrenal glomerulosa cells to angiotensin II, ACTH, K+, and ouabain.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Calcium; Dose-Response Relationship, Drug; Kinetics; Lanthanum; Ouabain; Potassium; Rats; Verapamil | 1981 |
Calcium ions and the influence of chagasic sera on the effects of ouabain on isolated rat atria.
Topics: Animals; Antibodies; Calcium; Chagas Cardiomyopathy; Heart Atria; Humans; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Propranolol; Rats; Receptors, Adrenergic, beta; Verapamil | 1981 |
Ca2+ transport by intact synaptosomes: the voltage-dependent Ca2+ channel and a re-evaluation of the role of sodium/calcium exchange.
Topics: Animals; Biological Transport, Active; Calcium; Cell Membrane; Cerebral Cortex; Female; Guinea Pigs; Ion Channels; Kinetics; Male; Membrane Potentials; Ouabain; Sodium; Synaptosomes; Verapamil | 1981 |
Hypoxia, calcium fluxes, and inotropic state: studies in cultured heart cells.
Topics: Animals; Calcium; Cells, Cultured; Chick Embryo; Heart; Ion Channels; Myocardial Contraction; Myocardium; Ouabain; Oxygen; Potassium; Sodium; Stimulation, Chemical; Verapamil | 1982 |
Electrical and contractile consequences of Na+ or Ca2+ gradient reduction in cultured heart cells.
Topics: Animals; Calcimycin; Calcium; Ion Channels; Lanthanum; Monensin; Myocardial Contraction; Ouabain; Rats; Sodium; Tetrodotoxin; Verapamil | 1982 |
Role of calcium in cAMP-mediated effects in the elasmobranch rectal gland.
Topics: Amphotericin B; Animals; Calcimycin; Calcium; Cyclic AMP; Dogfish; Ouabain; Oxygen Consumption; Receptors, Drug; Salt Gland; Sharks; Sodium; Sodium-Potassium-Exchanging ATPase; Theophylline; Verapamil | 1983 |
Possible mechanisms involved in the spontaneous rhythmicity in the guinea-pig tracheal smooth muscle as induced by glucose removal.
Topics: Animals; Atropine; Calcimycin; Female; Glucose; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Propranolol; Tetrodotoxin; Verapamil | 1983 |
Effects of EDTA and verapamil on renin release in dogs.
Topics: Animals; Calcium; Dogs; Edetic Acid; Infusions, Intra-Arterial; Kidney; Kidney Function Tests; Ouabain; Renal Artery; Renal Circulation; Renin; Verapamil | 1983 |
The role of calcium in the control of renin release.
Topics: Angiotensin II; Animals; Calcium; Edetic Acid; In Vitro Techniques; Isoproterenol; Kidney Cortex; Mice; Ouabain; Rats; Rats, Inbred Strains; Renin; Verapamil | 1984 |
Effect of 2-nicotinamidethyl nitrate (SG-75) on the membrane potential of left atrial muscle fibres of the dog. Increase in potassium conductance.
Topics: Animals; Atropine; Chlorides; Dogs; Drug Interactions; Heart; In Vitro Techniques; Membrane Potentials; Methacholine Compounds; Neural Conduction; Niacinamide; Nicorandil; Nitrates; Ouabain; Potassium; Vasodilator Agents; Verapamil | 1980 |
Studies on the calcium antagonistic action of tetrandrine: VIII. Antagonistic effects of tetrandrine on ouabain-induced contraction of coronary arterial strips.
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Calcium Chloride; Coronary Vessels; Electric Stimulation; In Vitro Techniques; Ouabain; Swine; Vasoconstriction; Verapamil | 1984 |
Effects of metoprolol on digitalis-resistant atrial tachyarrhythmias in chronic obstructive pulmonary disease.
Topics: Aged; Digitalis; Drug Therapy, Combination; Female; Heart Rate; Humans; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Tachycardia; Verapamil | 1984 |
Veratridine and ouabain stimulate calcium-dependent prolactin release.
Topics: Animals; Bromocriptine; Calcium; Cells, Cultured; Gallopamil; Male; Ouabain; Pituitary Gland, Anterior; Prolactin; Rats; Sodium; Tetrodotoxin; Verapamil; Veratridine; Veratrine | 1983 |
Effect of local infusion of ouabain on human forearm vascular resistance and on response to potassium, verapamil and sodium nitroprusside.
Topics: Adult; Ferricyanides; Forearm; Humans; Male; Middle Aged; Nitroprusside; Ouabain; Potassium; Regional Blood Flow; Sodium; Vascular Resistance; Verapamil | 1983 |
The contracture produced by sodium removal in the non-pregnant rat myometrium.
Topics: Animals; Calcium; Estrus; Female; In Vitro Techniques; Muscle Tonus; Muscle, Smooth; Myometrium; Ouabain; Pregnancy; Rats; Rats, Inbred Strains; Sodium; Uterine Contraction; Uterus; Verapamil | 1983 |
Action of the Na+ ionophore monensin on vascular smooth muscle of guinea-pig aorta.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Furans; Glucose; Guinea Pigs; Hypoxia; In Vitro Techniques; Male; Monensin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Phentolamine; Potassium; Prazosin; Sodium; Verapamil | 1984 |
Self-generated electrical currents through Xenopus neurulae.
Topics: Action Potentials; Amiloride; Animals; Electric Conductivity; Female; Male; Nervous System; Nervous System Physiological Phenomena; Ouabain; Sodium; Verapamil; Xenopus laevis | 1984 |
Sensitivity to halothane of the sodium efflux in single barnacle muscle fibers.
Topics: Animals; Calcium; Dantrolene; Egtazic Acid; Halothane; Membrane Potentials; Muscles; Ouabain; Procaine; Sodium; Thoracica; Verapamil | 1981 |
Verapamil-induced changes in digoxin kinetics and intraerythrocytic sodium concentration.
Topics: Adult; Digoxin; Drug Interactions; Erythrocytes; Humans; Kinetics; Male; Metabolic Clearance Rate; Ouabain; Sodium; Verapamil | 1983 |
Effects of amrinone on atrioventricular conduction in the intact canine heart.
Topics: Aminopyridines; Amrinone; Animals; Bundle of His; Cardiotonic Agents; Dogs; Heart Conduction System; Ouabain; Propranolol; Sinoatrial Node; Verapamil | 1983 |
Antiarrhythmic effect of KB-944, a new calcium antagonist. A comparison with verapamil and diltiazem.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Benzothiazoles; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Epinephrine; Guinea Pigs; Male; Ouabain; Rats; Thiazoles; Verapamil | 1982 |
Comparison of voltage-tension relationship between peak and terminal tonic tensions induced by longer depolarization in the bullfrog myocardium.
Topics: Animals; Calcium; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Ouabain; Rana catesbeiana; Sodium; Temperature; Verapamil | 1981 |
Calcium in the control of renin secretion: Ca2+ influx as an inhibitory signal.
Topics: Animals; Calcium; Dogs; Epinephrine; Kidney Cortex; Ouabain; Renin; Swine; Temperature; Verapamil | 1981 |
Importance of cellular calcium stores in glucose-stimulated insulin release.
Topics: Animals; Calcium; Calmodulin; Cytosol; Glucose; Insulin; Insulin Secretion; Male; Ouabain; Rats; Rats, Inbred Strains; Secretory Rate; Trifluoperazine; Verapamil | 1981 |
Extracellular calcium concentration and calcium blocking agents on the action of ouabain on isolated rat atrium.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Electric Stimulation; Gallopamil; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Verapamil | 1982 |
Effects of verapamil on positive inotropic stimulation in the left atrium and ventricle of conscious dogs.
Topics: Animals; Dogs; Electrocardiography; Heart Atria; Heart Rate; Heart Ventricles; Injections, Intravenous; Myocardial Contraction; Ouabain; Stimulation, Chemical; Verapamil | 1982 |
Effects of ouabain on high-K induced contractions of various smooth muscle tissues in the guinea-pig.
Topics: Animals; Calcium; Extracellular Space; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Sodium; Verapamil | 1982 |
Effects of the Na ionophore monensin on the contractile response and the movements of monovalent cations in the vascular smooth muscle of rabbit aorta.
Topics: Animals; Aorta, Thoracic; Cations, Monovalent; Furans; In Vitro Techniques; Lithium; Monensin; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Rabbits; Sodium; Verapamil | 1982 |
Calcium ion dependence of myogenic renal plasma flow autoregulation: evidence from the isolated perfused rat kidney.
Topics: Animals; Blood Flow Velocity; Calcium; Homeostasis; Male; Muscle, Smooth; Nifedipine; Ouabain; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Verapamil | 1982 |
Stimulation by injected guanosine triphosphate of the sodium efflux in barnacle muscle fibres pre-exposed to aldosterone.
Topics: Aldosterone; Animals; Biological Transport; Guanosine Triphosphate; In Vitro Techniques; Muscles; Ouabain; Sodium; Thoracica; Verapamil | 1981 |
Effects of tetrodotoxin, lidocaine, verapamil, and AHR-2666 on Ouabain-induced delayed afterdepolarizations in canine Purkinje fibers.
Topics: Action Potentials; Animals; Carbamates; Diastole; Dogs; Heart Conduction System; Ion Channels; Lidocaine; Ouabain; Purkinje Fibers; Pyrrolidines; Tetrodotoxin; Time Factors; Verapamil | 1980 |
Effect of inotropic agents on the calcium binding to isolated cardiac sarcolemma.
Topics: Animals; Caffeine; Calcium; Cations, Divalent; Cations, Monovalent; Dogs; Kinetics; Lanthanum; Myocardium; Neuraminidase; Ouabain; Sarcolemma; Verapamil | 1980 |
A quantitative relationship between cellular Na accumulation and relaxation produced by ouabain in the depolarized smooth muscle of guinea-pig taenia coli.
Topics: Animals; Calcium; Dinitrophenols; Guinea Pigs; In Vitro Techniques; Intestines; Intracellular Fluid; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Potassium; Sodium; Verapamil | 1980 |
Ionic basis of digitalis toxicity in mammalian ventricle: demonstration of transient inward current.
Topics: Animals; Calcium; Digitalis Glycosides; Digoxin; Electrophysiology; Ferrets; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Ouabain; Papillary Muscles; Verapamil | 1980 |
Pharmacokinetic studies of taurine in bovine Purkinje fibers.
Topics: Animals; Calcium; Cattle; Heart Conduction System; Incubators; Kinetics; Ouabain; Purkinje Fibers; Taurine; Tetrodotoxin; Time Factors; Verapamil | 1980 |
Effect of hypothalamic-hypophysary inhibitory factor on mesangial cell activation.
Topics: Analysis of Variance; Animals; Base Sequence; Calcium; Calcium Channel Blockers; Cattle; Cell Division; Cells, Cultured; Cytosol; DNA; Electrophoresis, Agar Gel; Enzyme Inhibitors; Gallic Acid; Gene Expression; Genes, fos; Genes, jun; Glomerular Mesangium; Molecular Sequence Data; Ouabain; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Surface Properties; Verapamil | 1995 |
Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Digitalis Glycosides; Disease Models, Animal; Disopyramide; Dogs; Epinephrine; Female; Flecainide; Injections, Intra-Arterial; Lidocaine; Male; Ouabain; Verapamil | 1995 |
Hypothalamic Na+,K(+)-ATPase inhibitor constricts pulmonary arteries of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hypertension; Hypothalamus; In Vitro Techniques; Male; Ouabain; Phentolamine; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Verapamil | 1993 |
Action of MgSO4 differs from moricizine and verapamil on ouabain-induced ventricular tachycardia in normomagnesemic conscious dogs.
Topics: Action Potentials; Animals; Dogs; Electric Stimulation; Female; Heart Block; Magnesium Deficiency; Magnesium Sulfate; Male; Moricizine; Neuromuscular Depolarizing Agents; Ouabain; Tachycardia, Supraventricular; Verapamil | 1994 |
Sodium/calcium exchange in rat cortical astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Caffeine; Calcium; Calcium-Transporting ATPases; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Cytosol; DNA, Complementary; Ion Transport; Microscopy, Fluorescence; Ouabain; Rats; RNA; RNA, Messenger; Ryanodine; Sodium; Terpenes; Thapsigargin; Verapamil | 1994 |
Hyperpolarization induced by sodium removal in rabbit sinoatrial node cells. Possible role of electrogenic sodium-calcium exchange.
Topics: Animals; Calcium; In Vitro Techniques; Lidocaine; Membrane Potentials; Ouabain; Quinacrine; Quinidine; Rabbits; Sinoatrial Node; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1995 |
Bursting firing of action potentials in central snail neurons elicited by d-amphetamine: role of the electrogenic sodium pump.
Topics: Action Potentials; Animals; Atropine; Dextroamphetamine; Dose-Response Relationship, Drug; Edetic Acid; Esophagus; Haloperidol; Hexamethonium; Magnesium; Neurons; Ouabain; Patch-Clamp Techniques; Phenobarbital; Potassium; Prazosin; Propranolol; Snails; Sodium; Sodium-Potassium-Exchanging ATPase; Temperature; Tubocurarine; Verapamil | 1995 |
Rhythmic contractions of isolated, pressurized small arteries from rat.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Pressure; Rats; Rats, Wistar; Ryanodine; Vasodilation; Verapamil | 1994 |
Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carrier Proteins; Cell Line; Cell Membrane; Cell Survival; Colchicine; Cricetinae; Cricetulus; Dactinomycin; Drug Interactions; Drug Resistance; Electrophoresis, Disc; Kinetics; Lung; Membrane Glycoproteins; Membrane Proteins; Ouabain; Sodium Azide; Verapamil; Vincristine | 1993 |
Effect of ouabain and verapamil on restoration of contraction by adrenaline during high K+ in the frog heart.
Topics: Animals; Decerebrate State; Epinephrine; Heart; Myocardial Contraction; Ouabain; Potassium; Rana temporaria; Verapamil | 1994 |
A role for ions in barrier recovery after acute perturbation.
Topics: Animals; Calcium; Calcium Channels; Calmodulin; Cell Membrane Permeability; Diazoxide; Dihydropyridines; Homeostasis; Ions; Mice; Mice, Hairless; Minoxidil; Ouabain; Permeability; Potassium; Potassium Channels; Skin; Skin Physiological Phenomena; Sodium-Potassium-Exchanging ATPase; Verapamil; Water-Electrolyte Balance | 1994 |
Insulin reduces contraction and intracellular calcium concentration in vascular smooth muscle.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; In Vitro Techniques; Insulin; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Serotonin; Vasodilation; Verapamil | 1993 |
Role of Na(+)-Ca2+ exchange in the regulation of vascular smooth muscle tension.
Topics: Animals; Caffeine; Calcium; Carrier Proteins; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Intracellular Membranes; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Ouabain; Phentolamine; Prazosin; Rabbits; Sarcolemma; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vascular Resistance; Verapamil | 1993 |
Effects of minocycline on accumulation of cyclic AMP in cerebral cortex of rat. A comparison with lithium.
Topics: Adenylyl Cyclases; Animals; Calcium; Cerebral Cortex; Colforsin; Cyclic AMP; In Vitro Techniques; Lithium; Male; Minocycline; Nerve Tissue Proteins; Norepinephrine; Ouabain; Rats; Rats, Wistar; Signal Transduction; Verapamil | 1993 |
Developmental differences in cardiac myocyte calcium homeostasis after steady-state potassium depolarization: mechanisms and implications for cardioplegia.
Topics: Aging; Amiloride; Animals; Calcium; Cytosol; Electrophysiology; Fura-2; Heart; Heart Arrest, Induced; Homeostasis; In Vitro Techniques; Myocardium; Ouabain; Potassium; Rabbits; Sarcolemma; Sarcoplasmic Reticulum; Verapamil | 1993 |
Inhibition of Na+/Ca2+ overload with R 56,865 protects against cardiac arrhythmias elicited by ouabain in vivo in guinea-pigs.
Topics: Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Electrocardiography; Guinea Pigs; Heart Rate; Lidocaine; Male; Ouabain; Piperidines; Sodium; Tetrodotoxin; Thiazoles; Verapamil | 1993 |
A significant fraction of calcium transients in intact guinea pig ventricular myocytes is mediated by Na(+)-Ca2+ exchange.
Topics: Amiloride; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Cells, Cultured; Guinea Pigs; Heart; Heart Ventricles; Membrane Potentials; Microscopy, Confocal; Microscopy, Fluorescence; Monensin; Muscle Proteins; Myocardium; Nickel; Ouabain; Potassium; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Sodium-Calcium Exchanger; Verapamil | 1995 |
Spontaneous firing of NG108-15 cells induced by transient exposure to ammonium chloride.
Topics: Amiloride; Ammonium Chloride; Animals; Cell Differentiation; Cell Membrane; Glioma; Hybrid Cells; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Ouabain; Rats; Tetrodotoxin; Time Factors; Vanadates; Verapamil | 1996 |
Mechanisms of inotropic responses of the isolated rat hearts to vanadate.
Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diuretics; Enzyme Inhibitors; Male; Myocardial Contraction; Ouabain; Perfusion; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium-Potassium-Exchanging ATPase; Vanadates; Verapamil | 1995 |
Light-sensitive response in melanophores of Xenopus laevis: I. Spectral characteristics of melanophore response in isolated tail fin of Xenopus tadpole.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Amphibians; Animals; Calcium; Calcium Channel Blockers; Cyclic CMP; Cyclic GMP; Enzyme Inhibitors; Gallic Acid; Ionophores; Light; Macrolides; Melanophores; Membrane Potentials; Ouabain; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Retinal Rod Photoreceptor Cells; Skin Pigmentation; Sodium-Potassium-Exchanging ATPase; Tail; Verapamil; Xenopus laevis | 1996 |
Protein kinase C induced changes in human airway smooth muscle tone: the effects of Ca2+ and Na+ transport.
Topics: Amiloride; Bronchi; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Muscle Contraction; Muscle, Smooth; Nifedipine; Ouabain; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium-Potassium-Exchanging ATPase; Verapamil | 1996 |
In vitro studies on calcium absorption from the gastrointestinal tract in small ruminants.
Topics: Animals; Biological Transport; Butyrates; Butyric Acid; Calcium; Digestive System; Digestive System Physiological Phenomena; Electrophysiology; Goats; Intestinal Absorption; Ouabain; Propionates; Rumen; Sheep; Verapamil | 1997 |
Mechanisms of positive inotropic action of flosequinan, hydralazine, and milrinone on mammalian myocardium.
Topics: Aequorin; Animals; Calcium Channel Blockers; Cardiotonic Agents; Carrier Proteins; Enzyme Inhibitors; Ferrets; Heart; Hydralazine; In Vitro Techniques; Male; Milrinone; Myocardial Contraction; Ouabain; Procaine; Pyridones; Quinolines; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Tetrodotoxin; Vasodilator Agents; Verapamil | 1997 |
Ca2+ sequestration as a determinant of chaos and mixed-mode dynamics in agonist-induced vasomotion.
Topics: Animals; Arteries; Calcium; Calcium-Transporting ATPases; Charybdotoxin; Ear; Endothelium, Vascular; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Male; Models, Cardiovascular; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nonlinear Dynamics; Ouabain; Rabbits; Ryanodine; Thapsigargin; Vasoconstriction; Vasodilation; Verapamil | 1997 |
The stereoisomers quinine and quinidine exhibit a marked stereoselectivity in the inhibition of hepatobiliary transport of cardiac glycosides.
Topics: Animals; Biliary Tract; Biological Transport; Calcium Channel Blockers; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes.
Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; In Vitro Techniques; Male; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
Effects of capsaicin and capsaicin desensitization on alanine accumulation in rat hemidiaphragms.
Topics: Alanine; Animals; Biological Transport; Capsaicin; Diaphragm; Female; In Vitro Techniques; Male; Ouabain; Rats; Rats, Sprague-Dawley; Verapamil | 1998 |
Mechanisms of action of endothelin-1 in rat adrenal.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Calcium; Calcium Channels; Cattle; Cells, Cultured; Cholesterol; Diglycerides; Endothelin-1; Male; Ouabain; Peptides, Cyclic; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sodium-Potassium-Exchanging ATPase; Verapamil; Viper Venoms; Zona Glomerulosa | 1998 |
Effects of urinary ouabain-like factors and vanadium diascorbate on calcium mobilization in porcine inner medullary collecting duct cells: comparison with the effects of ouabain and vasopressin.
Topics: Adult; Animals; Arginine Vasopressin; Ascorbic Acid; Biological Factors; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Gallic Acid; Humans; Kidney Medulla; Kidney Tubules, Collecting; Male; Organometallic Compounds; Ouabain; Renal Agents; Swine; Verapamil | 1998 |
Effects of quinidine, verapamil, nifedipine and ouabain on hysteresis in atrial refractoriness in the conscious dog: an approach to ionic mechanisms.
Topics: Animals; Dogs; Female; Heart; Ion Channels; Male; Nifedipine; Ouabain; Quinidine; Refractory Period, Electrophysiological; Sodium-Potassium-Exchanging ATPase; Verapamil | 1999 |
Possible stimulation of Na+-K+-ATPase by NO produced from sodium nitrite by ultraviolet light in mouse gastric fundal strip.
Topics: Amiloride; Animals; Calcium; Female; Gastric Fundus; In Vitro Techniques; Male; Mice; Muscle Relaxation; Nitric Oxide; Ouabain; Sodium; Sodium Nitrite; Sodium-Potassium-Exchanging ATPase; Ultraviolet Rays; Vanadates; Verapamil | 1999 |
[Effects of O-(4-ethoxyl-butyl)-berbamine on isolated frog hearts].
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Calcium Chloride; Cardiotonic Agents; Female; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Ouabain; Ranidae; Stimulation, Chemical; Verapamil | 1998 |
A fourth class of anti-dysrhythmic action? Effect of verapamil and ouabain toxicity, on atrial and ventricular intracellular potentials, and on other features of cardiac function.
Topics: Animals; Anti-Arrhythmia Agents; Bibliometrics; Heart; History, 20th Century; Membrane Potentials; Ouabain; Publishing; Verapamil | 2000 |
Inhibitors of Na-K-ATPase in human urine: effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: comparison with the effects of ouabain, angiotensin II, and arginine-vasopressin.
Topics: Adult; Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Ascorbic Acid; Biological Factors; Biological Transport; Calcium; Calcium Channel Blockers; Cardenolides; Cells, Cultured; Digoxin; Enzyme Inhibitors; Gallic Acid; Humans; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Nickel; Organometallic Compounds; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents; Verapamil | 2000 |
A Na+/Ca2+ exchanger inhibitor, KB-R7943, caused negative inotropic responses and negative followed by positive chronotropic responses in isolated, blood-perfused dog heart preparations.
Topics: Animals; Atropine; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hexamethonium; Imipramine; Isoproterenol; Myocardial Contraction; Ouabain; Perfusion; Propranolol; Sodium-Calcium Exchanger; Tetrodotoxin; Thiourea; Verapamil | 2000 |
Studies on the prevention of nigericin action in neuroblastoma X glioma hybrid (NG108-15) cells.
Topics: Calcium Channel Blockers; Electrophysiology; Enzyme Inhibitors; Ionophores; Membrane Potentials; Neuroblastoma; Nigericin; Ouabain; Quinidine; Tumor Cells, Cultured; Verapamil | 2000 |
Preceding stimulus frequency-dependent potentiation of the postrest shortening of the action potential duration in rabbits.
Topics: Action Potentials; Animals; Calcium; Electric Stimulation; Electrocardiography; Electrophysiology; In Vitro Techniques; Male; Ouabain; Papillary Muscles; Potassium Channel Blockers; Rabbits; Rest; Ryanodine; Sarcoplasmic Reticulum; Ventricular Function; Verapamil | 2000 |
Ionized magnesium in the homeostasis of cells: intracellular threshold for Mg(2+) in human platelets.
Topics: Blood Platelets; Cations, Divalent; Homeostasis; Humans; Magnesium; Ouabain; Verapamil | 2001 |
Role of membrane potential in vasomotion of isolated pressurized rat arteries.
Topics: Animals; Calcium; Cytosol; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Pressure; Rats; Rats, Sprague-Dawley; Vasomotor System; Verapamil | 2002 |
Na(+)/Ca(2+) exchanger in porcine oocytes.
Topics: Amiloride; Animals; Base Sequence; Bepridil; Calcium; Calcium Channel Blockers; Cell Membrane; Cloning, Molecular; Enzyme Inhibitors; Female; Fluorescent Dyes; Fura-2; Immunohistochemistry; Molecular Sequence Data; Oocytes; Ouabain; Pimozide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Swine; Verapamil | 2002 |
Palytoxin-induced increase in cytosolic-free Ca(2+) in mouse spleen cells.
Topics: Acrylamides; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Cnidarian Venoms; Cytosol; Dose-Response Relationship, Drug; Imidazoles; Lanthanum; Male; Mice; Nickel; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Ouabain; Sodium; Spleen; Tetrodotoxin; Verapamil | 2003 |
On the mechanisms of post-rest adaptation in the isolated electrically driven left atria of rats.
Topics: 4-Aminopyridine; Adaptation, Physiological; Animals; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Electric Stimulation; Female; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Rest; Theophylline; Vasodilator Agents; Verapamil | 2002 |
IPROVERATRIL: EXPERIMENTAL DATA ON CORONARY DILATATION AND ANTIARRHYTHMIC ACTION.
Topics: Animals; Anti-Arrhythmia Agents; Anura; Blood Pressure; Bradycardia; Cats; Chloroform; Coronary Vessels; Dilatation; Electrocardiography; Epinephrine; Heart; Heart Rate; Hypotension; Ouabain; Pharmacology; Quinidine; Rabbits; Research; Strophanthins; Toxicology; Vasodilator Agents; Ventricular Fibrillation; Verapamil | 1964 |
The heart of Daphnia magna: effects of four cardioactive drugs.
Topics: Animals; Cardiotonic Agents; Daphnia; Dose-Response Relationship, Drug; Heart; Heart Rate; Lethal Dose 50; Metaproterenol; Metoprolol; Ouabain; Sodium Dodecyl Sulfate; Verapamil | 2003 |
[Effect of ouabain on the aortic rings of guinea pig and its interactions with Ca2+, norepinephrine].
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Calcium Chloride; Drug Synergism; Female; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Ouabain; Verapamil | 2003 |
Positive inotropic and negative chronotropic effects of proton pump inhibitors in isolated rat atrium.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Heart Atria; Imidazoles; In Vitro Techniques; Lansoprazole; Male; Milrinone; Myocardial Contraction; Omeprazole; Ouabain; Phosphodiesterase Inhibitors; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Theophylline; Verapamil | 2005 |
Reduction of perifusate magnesium alters inotropic response of papillary muscle to ion channel modulators.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Female; Humans; Ion Channels; Magnesium; Myocardial Contraction; Myocytes, Cardiac; Ouabain; Papillary Muscles; Perfusion; Rats; Rats, Sprague-Dawley; Ryanodine; Verapamil | 2005 |
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Bacterial Agents; Atropine; Azithromycin; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Ouabain; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Trachea; Verapamil | 2006 |
Zinc ions efflux from lymphocytes in vitro in the presence of a calcium and magnesium ionic environment and its changes following administration of verapamil.
Topics: Adult; Calcium; Calcium Channel Blockers; Cations, Divalent; Female; Humans; Lymphocytes; Magnesium; Male; Ouabain; Verapamil; Zinc | 2007 |
Rhythmic contractility in the hepatic portal "corkscrew" vein of the rat snake.
Topics: Angiotensin II; Animals; Calcium; Catecholamines; Colubridae; Immunohistochemistry; Indomethacin; Liver; Ouabain; Portal Vein; Prostaglandins; Sodium-Potassium-Exchanging ATPase; Species Specificity; Vasoconstriction; Verapamil | 2009 |
Calcium transport and homeostasis in gill cells of a freshwater crab Dilocarcinus pagei.
Topics: Amiloride; Animals; Biological Transport; Brachyura; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Epithelial Cells; Gills; Homeostasis; Kinetics; Nifedipine; Ouabain; Sodium; Sodium-Calcium Exchanger; Thiourea; Vanadates; Verapamil | 2010 |
Vasoconstrictor and inotropic effects induced by the root bark extracts of Anthocleista schweinfurthii.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cardiotonic Agents; Chromatography, Thin Layer; Democratic Republic of the Congo; Gentianaceae; Heart; In Vitro Techniques; Male; Methylene Chloride; Myocardial Contraction; Ouabain; Plant Extracts; Plant Roots; Propranolol; Rana esculenta; Rats; Sodium-Potassium-Exchanging ATPase; Solvents; Spectrophotometry, Ultraviolet; Vasoconstrictor Agents; Verapamil; Water | 2010 |
The effect of different kinds of electrolyte and non-electrolyte solutions on the survival rate and morphology of zebrafish Danio rerio embryos.
Topics: Amiloride; Animals; Calcium Channel Blockers; Electrolytes; Embryo, Nonmammalian; Enzyme Inhibitors; Growth Inhibitors; Inhibitory Concentration 50; Mercury Compounds; Ouabain; Polyvinyl Alcohol; Sodium Channel Blockers; Sucrose; Survival Analysis; Time Factors; Verapamil; Zebrafish | 2009 |
In vitro studies on intestinal calcium and phosphate transport in horses.
Topics: Animals; Blotting, Western; Calbindins; Calcium; DNA, Complementary; Electrophysiological Phenomena; Epithelium; Horses; In Vitro Techniques; Intestinal Mucosa; Intestines; Ion Transport; Membrane Transport Modulators; Ouabain; Phosphates; Plasma Membrane Calcium-Transporting ATPases; Reverse Transcriptase Polymerase Chain Reaction; S100 Calcium Binding Protein G; Verapamil | 2012 |
Extracellular Ca2+ influx is crucial for the early embryonic development of the sea urchin Echinometra lucunter.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calmodulin; Edetic Acid; Egtazic Acid; Embryo, Nonmammalian; Fluorescence; Ion Channel Gating; Ion Transport; Nigericin; Ouabain; Sea Urchins; Valinomycin; Verapamil | 2012 |
A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries.
Topics: Animals; Bradykinin; Carbenoxolone; Catalase; Colforsin; Coronary Vessels; Female; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Ouabain; Oxadiazoles; Peptides; Polyethylene Glycols; Quinoxalines; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents; Vasodilation; Verapamil | 2014 |