ouabain has been researched along with valproic acid in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| el-Mailakh, RS; el-Masri, MA; Hennion, JP; Huff, MO | 1 |
| Arent, CO; Ferreira, CL; Fries, GR; Jornada, LK; Kapczinski, F; Moretti, M; Padilha, PT; Quevedo, J; Valvassori, SS | 1 |
| Arent, CO; Dal-Pizzol, F; Ferreira, CL; Jornada, LK; Mina, F; Moretti, M; Quevedo, J; Steckert, AV; Valvassori, SS | 1 |
| Gonçalves, CL; Lopes-Borges, J; Quevedo, J; Streck, EL; Tonin, PT; Valvassori, SS; Varela, RB; Vieira, JS | 1 |
| Amboni, RT; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Mariot, E; Quevedo, J; Valvassori, SS; Varela, RB | 1 |
| Carvalho, AF; Dal-Pont, GC; de Souza, CT; Farias, HR; Jornada, LK; Machado, AG; Peterle, BR; Quevedo, J; Resende, WR; Valvassori, SS | 1 |
| Dal-Pont, GC; Gava, FF; Quevedo, J; Resende, WR; Tye, SJ; Valvassori, SS; Varela, RB | 1 |
| Altun, A; Çiçekli, MN; Günaydın, C; Tiryaki, ES | 1 |
12 other study(ies) available for ouabain and valproic acid
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage.
Topics: Antimanic Agents; Apoptosis; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Lithium; Neuroblastoma; Neurons; Neuroprotective Agents; Ouabain; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured; Valproic Acid | 2002 |
Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain.
Topics: Amygdala; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hippocampus; Lithium Chloride; Male; Motor Activity; Ouabain; Rats; Rats, Wistar; Valproic Acid | 2010 |
Lithium and valproate modulate antioxidant enzymes and prevent ouabain-induced oxidative damage in an animal model of mania.
Topics: Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain; Catalase; Disease Models, Animal; Drug Interactions; Gene Expression Regulation, Enzymologic; Injections, Intraventricular; Lithium Chloride; Male; Ouabain; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Valproic Acid | 2011 |
Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; Butyric Acid; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Exploratory Behavior; Histone Deacetylase Inhibitors; Lithium; Male; Motor Activity; Ouabain; Rats; Rats, Wistar; Valproic Acid | 2015 |
Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats.
Topics: Affect; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Butyric Acid; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Histamine Antagonists; Lithium Compounds; Locomotion; Male; Motor Activity; Nerve Growth Factor; Ouabain; Prefrontal Cortex; Rats; Rats, Wistar; Treatment Outcome; Valproic Acid | 2015 |
Lithium and valproate act on the GSK-3β signaling pathway to reverse manic-like behavior in an animal model of mania induced by ouabain.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Frontal Lobe; Glycogen Synthase Kinase 3 beta; Hippocampus; Lithium Compounds; Locomotion; Male; Ouabain; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction; Thiazoles; Urea; Valproic Acid | 2017 |
HDAC inhibitors reverse mania-like behavior and modulate epigenetic regulatory enzymes in an animal model of mania induced by Ouabain.
Topics: Animals; Behavior, Animal; Bipolar Disorder; Butyric Acid; Corpus Striatum; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; Frontal Lobe; Hippocampus; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Locomotion; Male; Mania; Ouabain; Rats; Rats, Wistar; Signal Transduction; Treatment Outcome; Valproic Acid | 2020 |
GLP-1 agonist liraglutide improves ouabain-induced mania and depressive state
Topics: Animals; Antioxidants; Glucagon-Like Peptide 1; Glutathione; Glycogen Synthase Kinase 3 beta; Liraglutide; Lithium; Mania; Ouabain; Oxidants; Rats; Sucrose; Valproic Acid | 2022 |