ouabain has been researched along with thioguanine anhydrous in 79 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (77.22) | 18.7374 |
| 1990's | 17 (21.52) | 18.2507 |
| 2000's | 1 (1.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akera, T; Chang, CC; Trosko, JE | 1 |
| Corsaro, CM; Migeon, BR | 1 |
| Coffino, P; Friedrich, U | 1 |
| Arlett, CF; Cole, J | 2 |
| Defendi, V; Goldberg, S | 1 |
| Davidson, RL; Kaufman, ER | 1 |
| Curren, RD; Freeman, AE; Homer, CJ; Price, PJ | 1 |
| Nakamura, N; Okada, S | 1 |
| Gartler, SM; Raskind, WH | 1 |
| Duncan, ME | 1 |
| Siminovitch, L; Spandidos, DA | 1 |
| Aebersold, PM; Burki, HJ | 1 |
| Cleaver, JE | 2 |
| Barrett, JC; Ts'o, PO; Tsutsui, T | 1 |
| Chang, CC; Chu, EH; Trosko, JE; Yotti, LP | 1 |
| Jha, KK; Ozer, HL | 1 |
| Gong, C | 1 |
| Mirzayans, F; Mirzayans, R; Parry, JM | 1 |
| Doerr, CL; Harrington-Brock, K; Hozier, JC; Moore, MM; Parker, L | 1 |
| Berczi, I; Ramachandra, RN; Rector, ES; Sehon, AH | 1 |
| Fujiki, Y; Tsukamoto, T; Yokota, S | 1 |
| Bridges, BA; Cole, J; Richmond, FN | 1 |
| Jansson, K; Jansson, V | 1 |
| Boyes, BG; Karpinsky, K; Rogers, CG; Stapley, R | 1 |
| Kolar, C; Lawson, T; Nagel, D | 1 |
| Moustacchi, E; Papadopoulo, D | 1 |
| McEachern, D; Miller, BE; Miller, FR | 1 |
| Nishimura, T; Ozawa, S; Suzuki, H; Tamura, A; Tanaka, N | 1 |
| O'Brien, JM; Sieber, F | 1 |
| Dayan, J; Deguingand, S; Truzman, C | 1 |
| Dillard, LC; Effros, RB; Hulette, CM; Walford, RL | 1 |
| Basler, A; Obe, G; Scheutwinkel-Reich, M; Von der Hude, W | 1 |
| Box, KM; Hooper, ML; Smith, TA | 1 |
| Bignami, M; Calcagnile, A; Di Muccio, A; Dogliotti, E; Saffiotti, U; Terlizzese, M; Vitelli, A | 1 |
| Aizawa, S; Loeb, LA; Martin, GM | 1 |
| Banh, D; Landolph, JR; Patierno, SR | 1 |
| McInerney, D; Miller, BE; Miller, FR | 1 |
| Barrett, JC; Lee, TC; Oshimura, M | 1 |
| Aizawa, S; Loeb, LA; Martin, GM; Ohashi, M | 1 |
| Bilello, PA; Chang, CS; Ferrari, AC; Gallagher, RE; Muly, EC; Nickols, WA; Yen, RW | 1 |
| Hyodo, M; Ito, N; Suzuki, K; Yamashita, M | 1 |
| Jackson, D; McInerney, D; Miller, BE; Miller, FR | 1 |
| Anderson, TM; Christensen, CC; Conklin, PM; Hatch, GG; Langenbach, R; Nesnow, S | 1 |
| Heppner, GH; Yamashina, K | 1 |
| Frick, GP; Gentry, MK; Olsson, RA; Snow, JA | 1 |
| Han, A; Wells, RL | 1 |
| Gupta, RS; Siminovitch, L; Srinivasan, PR | 1 |
| Drobetsky, E; Meuth, M | 1 |
| Barrett, JC; Crawford, BD; Ts'o, PO; Tsutsui, T | 1 |
| Coffino, P; Friedrich, U; MacInnes, MA; van Daalen Wetters, T | 1 |
| Klein, G; Spira, J; Sümegi, J; Wiener, F; Wirschubsky, Z | 1 |
| Bauer, E; Cefalu, W; Frost, P; Kerbel, RS; Tartamella-Biondo, R | 1 |
| Adair, GM; Carver, JH; Wandres, DL | 1 |
| Fidler, IJ; Talmadge, JE | 1 |
| Gould, MN | 1 |
| Huberman, E; Jones, CA | 2 |
| Chang, CC; Liu, PK; Trosko, JE | 1 |
| Elkind, MM; Han, A; Hill, CK; Suzuki, F | 1 |
| Colella, CM; Mariani, T; Piras, A; Rainaldi, G | 1 |
| Burki, HJ; Goth-Goldstein, R | 1 |
| Gupta, RS; Singh, B | 1 |
| Huberman, E; Raveh, D; Slaga, TJ | 1 |
| Chen, DJ; Strniste, GF | 1 |
| Boyle, JM; Durrant, L; Fox, M; McMillan, S | 1 |
| Chang, CC; Schultz, RA; Trosko, JE | 1 |
| Price, GB; Sturgeon, JF; Till, JE | 1 |
| Burki, HJ; Lam, CK; Wood, RD | 1 |
| Morry, DW; Ts'o, PO | 1 |
| Balint, RF; Levine, AJ; Rosenstraus, MJ | 1 |
| Bhattacharyya, NP; Ganesh, A; Groden, J; Meuth, M; Skandalis, A | 1 |
| Aquilina, G; Bignami, M; Biondo, R; Dogliotti, E | 1 |
| Albertini, A; Ghielmi, S; Negrini, R; Osio, L; Verardi, R; Zanella, I | 1 |
| Pozuelo, JM; Santa Maria, A; Sanz, F | 1 |
| Barrett, JC; Hayashi, N; Huff, J; Maizumi, H; Tsutsui, T | 1 |
| Casciano, DA; Dass, SB; Heflich, RH | 1 |
| Donovan, PJ; Riggs, CW; Smith, GT | 1 |
1 review(s) available for ouabain and thioguanine anhydrous
| Article | Year |
|---|---|
The use of liver cell cultures in mutagenesis studies.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzopyrenes; Biotransformation; Carcinogens; Cell Line; Cells, Cultured; Cricetinae; Drug Resistance; Fibroblasts; Liver; Mutagenicity Tests; Mutagens; Ouabain; Rats; Thioguanine | 1980 |
78 other study(ies) available for ouabain and thioguanine anhydrous
| Article | Year |
|---|---|
Characterization of ultraviolet light-induced ouabain-resistant mutations in Chinese hamster cells.
Topics: Adenosine Triphosphatases; Cell Line; Dose-Response Relationship, Radiation; Drug Resistance; Mutation; Ouabain; Potassium; Sodium; Thioguanine; Ultraviolet Rays; X-Rays | 1978 |
Effect of ouabain resistance on human diploid fibroblasts carrying other genetic variants.
Topics: Cell Division; Chromosomes; Clone Cells; Drug Resistance; Fibroblasts; Genotype; Guanosine Monophosphate; Karyotyping; Mutation; Ouabain; Phenotype; Thioguanine | 1975 |
Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP.
Topics: Bucladesine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Kinetics; Lymphoma; Methylnitronitrosoguanidine; Mutagens; Mutation; Ouabain; Thioguanine | 1977 |
Methyl methanesulphonate mutagenesis in L5178Y mouse lymphoma cells.
Topics: Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Lymphoma; Mesylates; Methyl Methanesulfonate; Mutagens; Mutation; Neoplasms, Experimental; Ouabain; Thioguanine; Thymidine | 1978 |
Increased mutation rates in doubly viral transformed Chinese hamster cells.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cricetinae; Cricetulus; Drug Resistance; Embryo, Mammalian; Genetic Variation; Mutation; Ouabain; Phenotype; Polyomavirus; Simian virus 40; Thioguanine | 1979 |
Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA.
Topics: Bromodeoxyuridine; Bromouracil; Cells, Cultured; DNA; Drug Resistance; Mutation; Ouabain; Thioguanine | 1978 |
Mutagenesis of human cells by 3-methylcholanthrene.
Topics: Cell Line; Clone Cells; Drug Resistance; Epithelial Cells; Female; Fibroblasts; Humans; Male; Methylcholanthrene; Mutagens; Ouabain; Thioguanine; Xeroderma Pigmentosum | 1979 |
Cell-cycle dependency of BUdR-induced mutation for six genetic markers in cultured mammalian cells.
Topics: Animals; Asparagine; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA; Drug Resistance; Genes; L Cells; Methotrexate; Mice; Mutation; Ouabain; Thioguanine; Thymidine | 1979 |
The relationship between induced mutation frequency and chromosome dosage in established mouse fibroblast lines.
Topics: Alleles; Cell Line; DNA Replication; Drug Resistance; Female; Hypoxanthine Phosphoribosyltransferase; Karyotyping; Methylnitronitrosoguanidine; Mutation; Ouabain; Sex Chromosomes; Thioguanine; X Chromosome | 1978 |
Isolation and preliminary characterization of drug resistant mutants of human lymphoblastoid cells.
Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Cell Line; Cell Membrane; Drug Resistance; Humans; Hypoxanthine Phosphoribosyltransferase; Karyotyping; Mutation; Nucleotidases; Ouabain; Thioguanine | 1977 |
The relationship between transformation and somatic mutation in human and Chinese hamster cells.
Topics: Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Fructose; Genes; Mutation; Neoplasms, Experimental; Ouabain; Phenotype; Thioguanine; Urethane | 1978 |
Bromodeoxyuridine-induced mutations in synchronous Chinese hamster cells: temporal induction of 6-thioguanine and ouabain resistance during DNA replication.
Topics: Bromodeoxyuridine; Cell Line; DNA Replication; Drug Resistance; Mutagens; Ouabain; Thioguanine; Time Factors | 1978 |
Absence of interaction between X-rays and UV light in inducing ouabain- and thioguanine-resistant mutants in Chinese hamster cells.
Topics: Cell Line; DNA; Dose-Response Relationship, Radiation; Drug Resistance; Mutation; Ouabain; Phenotype; Thioguanine; Time Factors; Ultraviolet Rays; X-Rays | 1978 |
Induction of 6-thioguanine- and ouabain-resistant mutations in synchronized Syrian hamster cell cultures during different periods of the S phase.
Topics: Cell Cycle; Cell Line; DNA; Drug Resistance; Interphase; Mutation; Ouabain; Phenotype; Thioguanine; Time Factors; Ultraviolet Rays | 1978 |
Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light-induced 6-thioguanine and ouabain-resistant Chinese hamster cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; DNA Repair; Drug Resistance; Mutation; Neoplasms, Experimental; Ouabain; Phorbols; Tetradecanoylphorbol Acetate; Thioguanine; Time Factors; Ultraviolet Rays | 1977 |
Induction of thioguanine- and ouabain-resistant mutants and single-strand breaks in the DNA of Chinese hamster ovary cells by 3H-thymidine.
Topics: Animals; Cricetinae; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Drug Resistance; Female; Mutation; Ouabain; Ovary; Thioguanine; Thymidine; Tritium; Ultraviolet Rays; X-Rays | 1977 |
Expression of transformation in cell hybrids. I. Isolation and application of density-inhibited Balb/3T3 cells deficient in hypoxanthine phosphoribosyltransferase and resistant to ouabain.
Topics: Cell Line; Contact Inhibition; DNA; Drug Resistance; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Ouabain; Phenotype; Thioguanine; Transformation, Genetic | 1976 |
Ethyl methanesulphonate mutagenesis with L5178Y mouse lymphoma cells: a comparison of ouabain, thioguanine and excess thymidine resistance.
Topics: Animals; Cell Survival; Clone Cells; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Genetic Variation; Methotrexate; Mice; Mice, Inbred DBA; Mutation; Ouabain; Thioguanine; Thymidine | 1976 |
[Establishment and characteristics of a lymphoblastoid cell line (CKM) resistant to 6-TG and ouabain].
Topics: Cell Line, Transformed; Cell Transformation, Viral; Fetal Blood; Herpesvirus 4, Human; Humans; Hybridomas; Lymphocytes; Ouabain; Thioguanine | 1992 |
Application of the standard mutagenesis assay results in underestimation of ethyl methanesulphonate-induced mutations to ouabain-resistance in Chinese hamster cells.
Topics: Animals; Azaguanine; Cells, Cultured; Cricetinae; Drug Resistance; Ethyl Methanesulfonate; Mutagenicity Tests; Mutation; Ouabain; Thioguanine | 1992 |
Genotoxicity of 2-amino-6-N-hydroxyadenine (AHA) to mouse lymphoma and CHO cells.
Topics: Adenine; Animals; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Cricetulus; Drug Resistance; Mice; Micronucleus Tests; Mutagenesis; Mutagens; Ouabain; Sodium-Potassium-Exchanging ATPase; Thioguanine; Tumor Cells, Cultured | 1991 |
Development and characterization of ouabain-resistant human fusion partners.
Topics: Antibodies, Monoclonal; Antigens, Surface; Antigens, Viral; Azaguanine; Cell Fusion; Cell Line, Transformed; Drug Resistance; Epstein-Barr Virus Nuclear Antigens; Herpesvirus 4, Human; Histocompatibility Testing; Humans; Hybridomas; Immunoglobulin G; Karyotyping; Lipid A; Lipopolysaccharides; Lymphotoxin-alpha; Ouabain; Thioguanine; Tumor Cells, Cultured | 1991 |
Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes.
Topics: Acetyl-CoA C-Acetyltransferase; Acyltransferases; Animals; Cell Fusion; Cell Line; Cell Separation; Cricetinae; Cricetulus; Fatty Acid Desaturases; Female; Hybrid Cells; Microbodies; Microscopy, Electron; Mutation; Ouabain; Ovary; Protein Biosynthesis; RNA; Thioguanine | 1990 |
The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk +/- 3.7.2C mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei.
Topics: Adenine; Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Lymphoma; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Ouabain; Thioguanine; Thymidine Kinase; Trifluridine; Tumor Cells, Cultured | 1991 |
Induction of mutation in V79 Chinese hamster cells by tetrachlorohydroquinone, a metabolite of pentachlorophenol.
Topics: Animals; Cells, Cultured; Cricetinae; DNA; Dose-Response Relationship, Drug; Drug Resistance; Hydroquinones; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Mutagenicity Tests; Ouabain; Thioguanine | 1991 |
A statistical evaluation of the reproducibility of micronucleus, sister-chromatid exchange, thioguanine-resistance and ouabain-resistance assays in V79 cells exposed to ethyl methanesulfonate and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cells, Cultured; Drug Resistance; Ethyl Methanesulfonate; Liver; Male; Micronucleus Tests; Mutagenicity Tests; Mutagens; Ouabain; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Statistics as Topic; Thioguanine | 1990 |
The mutation of V79 cells by N-nitrosobis(2-oxopropyl)amine activated by pancreas acinar and duct tissue from Syrian hamsters and MRC-Wistar rats.
Topics: Animals; Biotransformation; Cricetinae; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Male; Mesocricetus; Mutagenicity Tests; Mutation; Nitrosamines; Ouabain; Pancreas; Pancreatic Ducts; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Thioguanine | 1990 |
Mutagenic effects photoinduced in normal human lymphoblasts by a monofunctional pyridopsoralen in comparison to 8-methoxypsoralen.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; DNA Damage; Drug Resistance; Furocoumarins; Humans; Hypoxanthine Phosphoribosyltransferase; Methoxsalen; Mutagenicity Tests; Mutagens; Ouabain; Sodium-Potassium-Exchanging ATPase; Thioguanine; Ultraviolet Rays | 1990 |
Efficiency of communication between tumour cells in collagen gel cultures.
Topics: Aminopterin; Animals; Cell Communication; Cell Division; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Mammary Neoplasms, Experimental; Mice; Ouabain; Thioguanine; Thymidine | 1990 |
Mechanisms affecting peplomycin sensitivity of Chinese hamster cell lines.
Topics: Animals; Bleomycin; Cell Line; Cricetinae; Cricetulus; Cysteine Endopeptidases; DNA; DNA Repair; Drug Resistance; Female; Glycoside Hydrolases; Mutation; Ouabain; Peplomycin; Thioguanine; Tritium | 1985 |
Mutagenicity of merocyanine 540-mediated photosensitization.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Female; Light; Mutagenicity Tests; Ouabain; Ovary; Pyrimidinones; Radiation-Sensitizing Agents; Thioguanine; Ultraviolet Rays | 1989 |
Study of the mutagenic activity of 6 hepatotoxic pharmaceutical drugs in the Salmonella typhimurium microsome test, and the HGPRT and Na+/K+ ATPase system in cultured mammalian cells.
Topics: Aminopyrine; Animals; Biotransformation; Cell Line; Clofibrate; Cricetinae; Cricetulus; Drug Resistance; Glycolates; Hypoxanthine Phosphoribosyltransferase; Liver; Lung; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Nitrofurans; Nitroquinolines; Ouabain; Oxamniquine; Perhexiline; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sodium-Potassium-Exchanging ATPase; Thioguanine; Ticrynafen | 1985 |
Production of a human monoclonal antibody to HLA by human-human hybridoma technology. A preliminary report.
Topics: Antibodies, Monoclonal; Cell Line; Cell Transformation, Viral; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Herpesvirus 4, Human; HLA Antigens; Humans; Hybridomas; Lymphocytes; Multiple Myeloma; Ouabain; Thioguanine | 1985 |
The restriction endonuclease Alu I induces chromosomal aberrations and mutations in the hypoxanthine phosphoribosyltransferase locus, but not in the Na+/K+ ATPase locus in V79 hamster cells.
Topics: Animals; Chromosome Aberrations; Cricetinae; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Mutation; Ouabain; Sodium-Potassium-Exchanging ATPase; Thioguanine | 1986 |
Clones defective in metabolic cooperation selected from a pluripotent feeder-dependent mouse embryonal carcinoma cell line.
Topics: Animals; Bucladesine; Cell Communication; Cell Differentiation; Clone Cells; Embryonal Carcinoma Stem Cells; Endoderm; Mice; Mutation; Neoplastic Stem Cells; Ouabain; Theophylline; Thioguanine; Uridine | 1986 |
Induction kinetics of mutations at two genetic loci, DNA damage and repair in CHO cells after different exposure times to N-ethyl-N-nitrosourea.
Topics: Animals; Chromosome Mapping; Cricetinae; Cricetulus; DNA; DNA Repair; Drug Resistance; Ethylnitrosourea; Hypoxanthine Phosphoribosyltransferase; Mutation; Nucleic Acid Conformation; Ouabain; Sodium-Potassium-Exchanging ATPase; Thioguanine | 1987 |
Aphidicolin-resistant mutator strains of mouse teratocarcinoma.
Topics: Animals; Aphidicolin; Cell Line; Chimera; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance; Mice; Mutation; Ouabain; Teratoma; Thioguanine | 1987 |
Transformation of C3H/10T1/2 mouse embryo cells to focus formation and anchorage independence by insoluble lead chromate but not soluble calcium chromate: relationship to mutagenesis and internalization of lead chromate particles.
Topics: Adipose Tissue; Animals; Calcium Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Chromates; Lead; Mice; Mice, Inbred C3H; Microscopy, Electron; Mutagenicity Tests; Ouabain; Thioguanine | 1988 |
Metabolic cooperation in vitro: differential ability of ouabain to uncouple normal, preneoplastic, and neoplastic mouse mammary cells.
Topics: Animals; Cell Communication; Drug Resistance; Female; In Vitro Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Ouabain; Precancerous Conditions; Thioguanine | 1986 |
Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture.
Topics: Animals; Arsenates; Arsenic; Arsenites; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cricetinae; Drug Resistance; Mutation; Ouabain; Sister Chromatid Exchange; Sodium Compounds; Thioguanine | 1985 |
Multipotent mutator strain of mouse teratocarcinoma cells.
Topics: Animals; Cell Line; Chimera; Cytarabine; Deoxycytosine Nucleotides; Drug Resistance; Embryonal Carcinoma Stem Cells; Mice; Mutation; Neoplasm Transplantation; Neoplastic Stem Cells; Ouabain; Phenotype; Teratoma; Thioguanine; Transplantation, Isogeneic | 1985 |
Characterization of differentiation-inducer-resistant HL-60 cells.
Topics: Bromodeoxyuridine; Butyrates; Butyric Acid; Cell Count; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid, Acute; Oncogenes; Ouabain; Phenotype; Tetradecanoylphorbol Acetate; Thioguanine; Tretinoin | 1985 |
An improved method for isolation of mutator mutants from mouse FM3A cells and their characterization.
Topics: Animals; Aphidicolin; Cell Line; Cell Separation; Cytarabine; Diterpenes; DNA Replication; Guanidines; Mammary Neoplasms, Experimental; Mice; Mutation; Nucleosides; Ouabain; Thioguanine; Tunicamycin | 1985 |
Metabolic cooperation between mouse mammary tumor subpopulations in three-dimensional collagen gel cultures.
Topics: Adenine; Animals; Cell Communication; Cell Line; Cells, Cultured; Collagen; Culture Media; Drug Resistance; Extracellular Matrix; Female; Gels; Mammary Neoplasms, Experimental; Mice; Ouabain; Thioguanine | 1986 |
Mutation and enhanced virus transformation of cultured hamster cells by exposure to gaseous ethylene oxide.
Topics: Adenoviruses, Simian; Air Pollutants; Animals; Cell Survival; Cell Transformation, Viral; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Embryo, Mammalian; Ethylene Oxide; Mesocricetus; Mutation; Ouabain; Thioguanine | 1986 |
Correlation of frequency of induced mutation and metastatic potential in tumor cell lines from a single mouse mammary tumor.
Topics: Animals; Cell Count; Cell Line; Drug Resistance; Ethyl Methanesulfonate; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mutation; Neoplasm Metastasis; Ouabain; Thioguanine | 1985 |
Adenosine uptake by canine heart.
Topics: Adenosine; Aminohydrolases; Animals; Biological Transport; Blood Pressure; Carbon Isotopes; Coronary Circulation; Deoxyadenosines; Dipyridamole; Dogs; Female; Heart Rate; Kinetics; Male; Myocardium; Nitrobenzenes; Ouabain; Phosphotransferases; Ribonucleosides; Thioguanine; Tritium | 1972 |
Action spectra for killing and mutation of Chinese hamster cells exposed to mid- and near-ultraviolet monochromatic light.
Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Female; Hypoxanthine Phosphoribosyltransferase; Mutation; Ouabain; Ovary; Sodium-Potassium-Exchanging ATPase; Spectrum Analysis; Thioguanine; Ultraviolet Rays | 1984 |
Studies on temperature-sensitive mutants of Chinese hamster ovary cells affected in DNA synthesis.
Topics: Alkylating Agents; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA; DNA Replication; Drug Resistance; Ethyl Methanesulfonate; Female; Genetic Complementation Test; Genetic Linkage; Hybrid Cells; Methyl Methanesulfonate; Mutation; Ouabain; Ovary; Protein Biosynthesis; RNA; Temperature; Thioguanine | 1980 |
Increased mutational rates in Chinese hamster ovary cells serially selected for drug resistance.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Emetine; Female; Fibroblasts; Floxuridine; Genes; Hybrid Cells; Mutation; Ouabain; Ovary; Thioguanine | 1983 |
Comparison between mutagenesis in normal and transformed Syrian hamster fibroblasts: difference in the temporal order of HPRT gene replication.
Topics: Animals; Cell Line; Clone Cells; Cricetinae; DNA Replication; Drug Resistance; Embryo, Mammalian; Genes; Hypoxanthine Phosphoribosyltransferase; Mesocricetus; Mutation; Ouabain; Sodium-Potassium-Exchanging ATPase; Thioguanine; Time Factors | 1981 |
Quantitative forward-mutation specificity of mono-functional alkylating agents, ICR-191, and aflatoxin B1 in mouse lymphoma cells.
Topics: Aflatoxin B1; Aflatoxins; Aminacrine; Aminoacridines; Animals; Bucladesine; Cell Line; Drug Resistance; Genetic Markers; Lymphoma; Mice; Mutation; Neoplasms, Experimental; Nitrogen Mustard Compounds; Ouabain; T-Lymphocytes; Thioguanine | 1982 |
Triplication of one chromosome No. 15 with an altered c-myc containing EcoRI fragment and elimination of the normal homologue in a T-cell lymphoma line of AKR origin (TIKAUT).
Topics: Animals; Cell Line; Chromosome Banding; Chromosome Mapping; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; DNA, Neoplasm; Drug Resistance; Karyotyping; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred AKR; Mutation; Nucleic Acid Hybridization; Oncogenes; Ouabain; T-Lymphocytes; Thioguanine; Trisomy | 1984 |
Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.
Topics: Adenocarcinoma; Animals; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mutagens; Ouabain; Thioguanine | 1983 |
Mutagenicity testing in mammalian cells. II. Validation of multiple drug-resistance markers having practical application for screening potential mutagens.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Adenine Phosphoribosyltransferase; Animals; Benzopyrenes; Biotransformation; Cricetinae; Cricetulus; Dimethylnitrosamine; Drug Resistance; Ethyl Methanesulfonate; Floxuridine; Genetic Markers; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagenicity Tests; Ouabain; Pentosyltransferases; Rats; Thioguanine; Thymidine Kinase | 1980 |
The evolution of biologic diversity in metastases.
Topics: Animals; Cell Line; Clone Cells; Drug Resistance; Mice; Mutation; Neoplasm Metastasis; Neoplasms, Experimental; Ouabain; Thioguanine | 1984 |
Mammary gland cell-mediated mutagenesis of mammalian cells by organ-specific carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Line; Cells, Cultured; Cricetinae; Drug Resistance; Female; Mammary Glands, Animal; Mutation; Ouabain; Rats; Thioguanine | 1980 |
Hypermutability of a UV-sensitive aphidicolin-resistant mutant of Chinese hamster fibroblasts.
Topics: Animals; Aphidicolin; Cells, Cultured; Chromosomes; Cricetinae; Cricetulus; Diphtheria Toxin; Diterpenes; Drug Resistance; Fibroblasts; Genes; Mutation; Ouabain; Thioguanine; Ultraviolet Rays | 1982 |
Suppressive action of near-ultraviolet light on ouabain resistance induced by far-ultraviolet light in Chinese hamster cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Ouabain; Polystyrenes; Thioguanine; Ultraviolet Rays | 1983 |
Thioguanine resistance, ouabain resistance and sister chromatid exchanges in V79/AP4 Chinese hamster cells treated with potassium dichromate.
Topics: Animals; Cell Line; Cell Survival; Chromates; Cricetinae; Cricetulus; Crossing Over, Genetic; Ouabain; Potassium Dichromate; Sister Chromatid Exchange; Thioguanine | 1982 |
Ethylnitrosourea-induced mutagenesis in asynchronous and synchronous Chinese hamster ovary cells.
Topics: Animals; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytological Techniques; Drug Resistance; Ethylnitrosourea; Female; Mutagens; Mutation; Nitrosourea Compounds; Ouabain; Ovary; Thioguanine | 1980 |
Mutagenic responses of five independent genetic loci in CHO cells to a variety of mutagens. Development and characteristics of a mutagen screening system based on selection for multiple drug-resistant markers.
Topics: Animals; Biotransformation; Cell Line; Cell Survival; Cricetinae; Cricetulus; Drug Resistance; Emetine; Female; Genes; Microsomes, Liver; Mutagenicity Tests; Mutagens; Ouabain; Ovary; Rats; Thioguanine | 1982 |
Cell-mediated mutagenesis and tumor-initiating activity of the ubiquitous polycyclic hydrocarbon, cyclopenta[c,d]pyrene.
Topics: Animals; Carcinogens; Cells, Cultured; Cricetinae; Drug Resistance; Mesocricetus; Mutagens; Neoplasms, Experimental; Ouabain; Pyrenes; Skin Neoplasms; Thioguanine | 1982 |
Cytotoxic and mutagenic properties of shale oil byproducts II. Comparison of mutagenic effects at five genetic markers induced by retort process water plus near ultraviolet light in Chinese hamster ovary cells.
Topics: Adenine; Animals; Cells, Cultured; Cricetinae; Cricetulus; Diphtheria Toxin; Dose-Response Relationship, Drug; Drug Resistance; Emetine; Female; Fuel Oils; Industrial Waste; Mutation; Ouabain; Ovary; Petroleum; Thioguanine; Ultraviolet Rays | 1982 |
Relative sensitivity of V79 and V79/79 cells to spontaneous and induced mutation to 6-thioguanine and ouabain resistance.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Ethyl Methanesulfonate; Lung; Methylnitrosourea; Mutagens; Mutation; Ouabain; Phenotype; Species Specificity; Thioguanine; Ultraviolet Rays | 1982 |
A sensitive hepatocyte-mediated assay for the metabolism of nitrosamines to mutagens for mammalian cells.
Topics: Animals; Cells, Cultured; Cricetinae; Diethylnitrosamine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Drug Resistance; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Mutagens; Nitrosamines; Ouabain; Rats; Thioguanine | 1980 |
The mutation studies of mutagen-sensitive and DNA repair mutants of Chinese hamster fibroblasts.
Topics: Animals; Cell Division; Cells, Cultured; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Radiation; Drug Resistance; Male; Mutation; Ouabain; Thioguanine; Ultraviolet Rays | 1981 |
Focus-forming ability and surface markers of hamster-human malignant lymphoma hybrids.
Topics: Animals; Cell Fusion; Cricetinae; Humans; Hybrid Cells; Karyotyping; Leukemia, Lymphoid; Lymphoma; Ouabain; Receptors, Antigen, B-Cell; Temperature; Thioguanine | 1980 |
UV-light-induced mutations in synchronous CHO cells.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diphtheria Toxin; Dose-Response Relationship, Radiation; Drug Resistance; Female; Ouabain; Ovary; Thioguanine; Ultraviolet Rays | 1980 |
Ploidy dependence of induced mutation frequency in transformed Syrian hamster cells.
Topics: Aneuploidy; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Drug Resistance; Embryo, Mammalian; Ethyl Methanesulfonate; Gene Frequency; Genes, Dominant; Genes, Recessive; Hypoxanthine Phosphoribosyltransferase; Mesocricetus; Mutagens; Ouabain; Phenotype; Thioguanine; Time Factors | 1980 |
Pluripotency of somatic cell hybrids between nullipotent and pluripotent embryonal carcinoma cells.
Topics: Animals; Cell Differentiation; Drug Resistance; Ethyl Methanesulfonate; Genes, Dominant; Hybrid Cells; Male; Mice; Neoplasms, Experimental; Ouabain; Phenotype; Teratoma; Thioguanine | 1980 |
Mutator phenotypes in human colorectal carcinoma cell lines.
Topics: Cell Line; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA, Neoplasm; DNA, Satellite; Genetic Markers; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Mutation; Ouabain; Repetitive Sequences, Nucleic Acid; Thioguanine; Tumor Cells, Cultured | 1994 |
Genetic consequences of tolerance to methylation DNA damage in mammalian cells.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Aza Compounds; Base Sequence; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Damage; Drug Resistance; Guanine; Methylation; Methylnitrosourea; Molecular Sequence Data; Mutation; Ouabain; Thioguanine | 1993 |
Selection of new heteromyeloma cell lines for the obtainment of human monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Cell Division; Cell Fusion; Cell Line, Transformed; Chromosomes, Human; Culture Media; Hepatitis B Antibodies; Hepatitis B Core Antigens; Herpesvirus 4, Human; Humans; Hybrid Cells; Hybridomas; Hypoxanthine Phosphoribosyltransferase; Immunoglobulin M; Mice; Multiple Myeloma; Ouabain; Recombinant Proteins; Selection, Genetic; Thioguanine; Tumor Cells, Cultured | 1993 |
Cytotoxicity and mutagenicity of 6-aminonicotinamide in Chinese hamster ovary cells.
Topics: 6-Aminonicotinamide; Animals; Cell Death; CHO Cells; Cricetinae; Genetic Markers; Hypoxanthine Phosphoribosyltransferase; Microsomes, Liver; Mutagenesis; Ouabain; Proteins; Sodium-Potassium-Exchanging ATPase; Teratogens; Thioguanine | 1996 |
Benzene-, catechol-, hydroquinone- and phenol-induced cell transformation, gene mutations, chromosome aberrations, aneuploidy, sister chromatid exchanges and unscheduled DNA synthesis in Syrian hamster embryo cells.
Topics: Aneuploidy; Animals; Benzene; Carcinogens; Catechols; Cells, Cultured; Chromosome Aberrations; Cricetinae; DNA; Hydroquinones; Mutagenesis; Ouabain; Phenol; Phenols; Reproducibility of Results; Sister Chromatid Exchange; Sympatholytics; Thioguanine; Transformation, Genetic | 1997 |
The mutagenic response at the ouabain resistance locus in T cells of mice exposed to N-ethyl-N-nitrosourea parallels the response at the Hprt locus and correlates with mutation target size.
Topics: Animals; Chromosome Mapping; Ethylnitrosourea; Female; Hypoxanthine Phosphoribosyltransferase; Mice; Mice, Inbred C57BL; Mutagens; Mutation; Ouabain; T-Lymphocytes; Thioguanine | 1997 |
Hamster and rat fetal cells have low spontaneous mutation frequencies and rates.
Topics: 2-Aminopurine; Animals; Brain; Breeding; Cell Survival; Cells, Cultured; Cricetinae; Diphtheria Toxin; Dose-Response Relationship, Drug; Drug Resistance; Female; Fetus; Gene Frequency; Male; Mesocricetus; Mutation; Ouabain; Pregnancy; Rats; Rats, Inbred F344; Thioguanine | 2001 |