ouabain and ouabagenin

ouabain has been researched along with ouabagenin in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (25.71)	18.7374
1990's	8 (22.86)	18.2507
2000's	9 (25.71)	29.6817
2010's	9 (25.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ball, WJ; Farr, CD; Fishwild, DM; Nair, AC; Tabet, MR; Wang, X; Welsh, WJ	1
Bryant, HJ; Chen, S; Eliades, DC; Haddy, FJ; Pamnani, MB; Schooley, JF; Yuan, CM	1
Bose, D; Chan, TL; Chau, TC	1
Bose, D; Bouchard, RA; Hryshko, LV; Kobayashi, T	1
Nielsen-Kudsk, F; Vigholt Sørensen, E	1
Bárcenas-Ruiz, L; Kabela, E; Núñez-Durán, H; Riboni, L; Ubaldo, E	1
Bose, D; Cote, D; Elliott, D; Kim, RS; Kumar, VP; LaBella, FS; Templeton, JF	1
Bihler, I; Kim, RS; LaBella, FS	1
Yoda, A; Yoda, S	1
Gati, I; Lichtstein, D; Ovadia, H	1
Banerjee, S; Chakravarty, AK; Chatterjee, M; Ganguly, S; Sarkar, BR	1
Kaaja, RJ; Lewis, JG; Lewis, LK; Nicholls, MG; Pidgeon, GB; Richards, AM; Yandle, TG	1
Bates, RB; Dolata, DP; Gangwar, S; Gnabre, JN; Pinnas, JL	1
Lingrel, JB; O'Brien, WJ; Wallick, ET	1
Banerjee, S; Chatterjee, M; Ganguly, S; Sarkar, BR	1
Akritopoulou-Zanze, I; Berova, N; Dong, JG; Guo, J; Harada, N; Nakanishi, K	1
Hamilton, BP; Hamilton, J; Hamlyn, JM; Manunta, P; Rogowski, AC	1
Nishio, M; Ruch, SR; Wasserstrom, JA	1
BARAN, JS; KAGAWA, CM; KROL, WF	1
Aistrup, GL; Kelly, JE; Nishio, M; Ruch, SW; Sheehan, K; Wasserstrom, JA	1
Banerjee, S; Debnath, MC; Ganguly, S; Sarkar, BR	1
Geering, K; Horisberger, JD; Kharoubi-Hess, S; Modyanov, NN; Radkov, R; Schaer, D	1
Costa, PR; da Silva, AJ; Noël, F; Pôças, ES; Touza, NA	1
Deslongchamps, P; Phoenix, S; Sridhar Reddy, M; Zhang, H	1
ANDERSON, RC; CHEN, KK; WORTH, HM	1
Deslongchamps, P; Phoenix, S; Reddy, MS; Zhang, H	1
Capella, LS; Capella, MA; Cruz, FC; Lopes, AG; Nunes-Lima, LT; Oliveira, MM; Palmieri, RR; Valente, RC	1
Fridman, E; Lichtstein, D; Rosen, H	1
Baran, PS; Renata, H; Zhou, Q	1
Kipenko, AV; Krylov, BV; Lopatina, EV; Penniyaynen, VA	1
Baran, PS; Dünstl, G; Felding, J; Merchant, RR; Renata, H; Yeh, CH; Zhou, Q	1
Kipenko, AV; Krylov, BV; Lopatina, EV; Penniiaĭnen, VA	1
Kataoka, T; Okina, Y; Takada, Y; Takeuchi, F; Yokomichi, T	1
Fukunaga, K; Kato, S; Okada, M; Shinoda, Y; Shioda, N; Tamura, S; Ueda, M; Ui-Tei, K	1
Aye, Y; Bhattarai, B; Curtis Long, MJ; Kaplan, W; Khatri, HR; Li, Z; Nagorny, P	1

Reviews

1 review(s) available for ouabain and ouabagenin

Article	Year
Scattered light intensity fluctuation in the canine ventricular myocardium: correlation with inotropic drug effect. Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:9 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Colforsin; Dobutamine; Dogs; Heart; Light; Myocardial Contraction; Ouabain; Scattering, Radiation; Temperature	1988

Article

Year

Scattered light intensity fluctuation in the canine ventricular myocardium: correlation with inotropic drug effect.

Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:9

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Colforsin; Dobutamine; Dogs; Heart; Light; Myocardial Contraction; Ouabain; Scattering, Radiation; Temperature

1988

Trials

1 trial(s) available for ouabain and ouabagenin

Article	Year
Ouabain is not detectable in human plasma. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:5 Topics: Animals; Antibodies; Antibody Specificity; Chromatography, High Pressure Liquid; Cross Reactions; Digoxin; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Heart Failure; Humans; Kidney Failure, Chronic; Ouabain; Pre-Eclampsia; Pregnancy; Rabbits; Sensitivity and Specificity; Steroids; Strophanthidin; Vasopressins	1994

Article

Year

Ouabain is not detectable in human plasma.

Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:5

Topics: Animals; Antibodies; Antibody Specificity; Chromatography, High Pressure Liquid; Cross Reactions; Digoxin; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Heart Failure; Humans; Kidney Failure, Chronic; Ouabain; Pre-Eclampsia; Pregnancy; Rabbits; Sensitivity and Specificity; Steroids; Strophanthidin; Vasopressins

1994

Other Studies

33 other study(ies) available for ouabain and ouabagenin

Article	Year
Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis. Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15 Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Binding, Competitive; Carbohydrate Sequence; Digoxin; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin Fab Fragments; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Ouabain; Progesterone; Quantitative Structure-Activity Relationship; Radioligand Assay	2002
Effects of three sodium-potassium adenosine triphosphatase inhibitors. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:3 Topics: Angiotensin II; Animals; Blood Pressure; Bufanolides; Diuresis; Heart Rate; Male; Natriuresis; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase	1991
Role of sarcoplasmic reticulum in digitalis-induced electrical and mechanical oscillations in the heart. The Canadian journal of cardiology, 1987, Volume: 3, Issue:4 Topics: Animals; Caffeine; Calcium; Cardiac Complexes, Premature; Digitalis; Dogs; Female; Heart Ventricles; Male; Manganese; Myocardial Contraction; Ouabain; Plants, Medicinal; Plants, Toxic; Ryanodine; Sarcoplasmic Reticulum	1987
Single and combined myocardial pharmacodynamics of xamoterol, isoprenaline and g-strophanthin in the isolated rabbit heart. European journal of pharmacology, 1986, Jun-24, Volume: 125, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Coronary Circulation; Drug Interactions; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption; Propanolamines; Rabbits; Xamoterol	1986
Ouabain uptake by endocytosis in isolated guinea pig atria. The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 1 Topics: Ammonium Chloride; Animals; Biological Transport; Endocytosis; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Microscopy, Electron; Myocardial Contraction; Myocardium; Ouabain; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Trifluoperazine	1988
Progesterone derivatives that bind to the digitalis receptor: synthesis of 14 beta-hydroxyprogesterone. A novel steroid with positive inotropic activity. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Animals; Chemical Phenomena; Chemistry; Dogs; Female; Guinea Pigs; Hydroxyprogesterones; Male; Mucor; Myocardial Contraction; Ouabain; Progesterone; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical	1987
Progesterone derivatives that bind to the digitalis receptor: effects on 86Rb uptake and contractility in the isolated guinea pig heart. Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:9 Topics: Animals; Chlormadinone Acetate; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Ouabain; Progesterone; Radioisotopes; Receptors, Drug; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase	1984
The interaction of ouabagenin and (Na+ + K+)-ATPase in the presence of Na+, Mg2+, and ATP. Molecular pharmacology, 1981, Volume: 19, Issue:1 Topics: Adenosine Triphosphate; Animals; Cardiac Glycosides; Chemical Phenomena; Chemistry, Physical; Drug Stability; Electric Organ; Electrophorus; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; Ouabain; Protein Binding; Sodium; Sodium-Potassium-Exchanging ATPase	1981
Digitalis-like compounds in the toad Bufo viridis: interactions with plasma proteins. Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 2 Topics: Animals; Blood Proteins; Bufanolides; Bufonidae; Digoxigenin; Female; Male; Molecular Weight; Ouabain; Protein Binding; Skin	1993
Iodoacetylated ouabagenins: their syntheses, spectroscopic characterizations, and stability studies. Steroids, 1995, Volume: 60, Issue:6 Topics: Acetylation; Chromatography, High Pressure Liquid; Drug Stability; Iodine Radioisotopes; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Myocardium; Ouabain; Sodium-Potassium-Exchanging ATPase	1995
Tylophora compounds as Na+/K(+)-ATPase inhibitors. General pharmacology, 1993, Volume: 24, Issue:5 Topics: 4-Butyrolactone; Animals; Basement Membrane; Crystallography, X-Ray; In Vitro Techniques; Kidney Cortex; Models, Molecular; Molecular Conformation; Ouabain; Phenanthrenes; Plants; Rabbits; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids	1993
Amino acid residues of the Na,K-ATPase involved in ouabain sensitivity do not bind the sugar moiety of cardiac glycosides. The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11 Topics: Amino Acid Sequence; Animals; Cell Membrane; HeLa Cells; Humans; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Ouabain; Sheep; Sodium-Potassium-Exchanging ATPase; Transfection	1993
Technetium-99m radiolabeled ouabagenin-cysteine conjugate: biological evaluation in animal models. Nuclear medicine and biology, 1996, Volume: 23, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Drug Stability; Guinea Pigs; Isotope Labeling; Ligands; Magnetic Resonance Spectroscopy; Ouabain; Rabbits; Rats; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Technetium Compounds; Tissue Distribution	1996
Theoretical calculation of circular dichroic exciton-split spectra in presence of three interacting 2-naphthoate chromophores. Enantiomer, 1997, Volume: 2, Issue:5 Topics: Carboxylic Acids; Circular Dichroism; Models, Molecular; Monte Carlo Method; Naphthalenes; Ouabain; Spectrophotometry, Ultraviolet; Stereoisomerism	1997
Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Aldosterone; Animals; Blood Pressure; Cardiotonic Agents; Chronic Disease; Digitoxin; Digoxin; Hypertension, Renal; Kidney; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Tissue Distribution	2000
Effect of cardiac glycosides on action potential characteristics and contractility in cat ventricular myocytes: role of calcium overload. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1 Topics: Action Potentials; Animals; Calcium; Cardiac Glycosides; Cardiotonic Agents; Cats; Drug Interactions; Electrophysiology; Heart Ventricles; Muscle Cells; Muscle Contraction; Ouabain	2003
URINARY ELECTROLYTE EFFECTS OF OUABAIN AND OUABAGENIN IN ADRENALECTOMIZED RATS. Archives internationales de pharmacodynamie et de therapie, 1964, Aug-01, Volume: 150 Topics: Adrenalectomy; Chlorides; Diuresis; Diuretics; Electrolytes; Natriuresis; Ouabain; Pharmacology; Potassium; Rats; Research; Spironolactone; Triamterene	1964
Ouabain increases sarcoplasmic reticulum calcium release in cardiac myocytes. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:3 Topics: Animals; Calcium; Calcium Channels; Cats; Cells, Cultured; Glycosides; Heart; Myocytes, Cardiac; Ouabain; Rats; Sarcoplasmic Reticulum; Sodium	2004
Preparation of 99mTc-labelled conjugates of ouabagenin and their biological evaluation in animal models. Nuclear medicine communications, 2006, Volume: 27, Issue:3 Topics: Animals; Guinea Pigs; Heart; Isotope Labeling; Metabolic Clearance Rate; Models, Animal; Myocardium; Organ Specificity; Ouabain; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Rats; Species Specificity; Technetium; Tissue Distribution	2006
Role of homologous ASP334 and GLU319 in human non-gastric H,K- and Na,K-ATPases in cardiac glycoside binding. Biochemical and biophysical research communications, 2007, Apr-27, Volume: 356, Issue:1 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding, Competitive; Biological Transport; Cardiac Glycosides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Humans; Membrane Potentials; Mutation; Oocytes; Ouabain; Protein Subunits; Proton Pump Inhibitors; Rabbits; Rats; Rubidium Radioisotopes; Sequence Homology, Amino Acid; Sodium-Potassium-Exchanging ATPase; Xenopus laevis	2007
Synergistic interaction between ouabain and 8-methoxy-3,9-dihydroxy coumestan, a non-steroidal synthetic inhibitor of Na+,K+-ATPase. Life sciences, 2007, Sep-22, Volume: 81, Issue:15 Topics: Animals; Benzofurans; Binding Sites; Coumarins; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Kidney; Male; Ouabain; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	2007
Total synthesis of ouabagenin and ouabain. Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:7 Topics: Cyclization; Molecular Structure; Ouabain	2008
Ouabagenin. The Journal of pharmacology and experimental therapeutics, 1948, Volume: 93, Issue:2 Topics: Ouabain	1948
Total synthesis of ouabagenin and ouabain. Chemistry, an Asian journal, 2009, May-04, Volume: 4, Issue:5 Topics: 4-Butyrolactone; Crystallography, X-Ray; Cyclization; Ouabain; Oxidation-Reduction; Stereoisomerism	2009
Diverse actions of ouabain and its aglycone ouabagenin in renal cells. Cell biology and toxicology, 2010, Volume: 26, Issue:3 Topics: Animals; Cell Line; Dogs; Dose-Response Relationship, Drug; Haplorhini; Kidney; Microscopy, Fluorescence; Ouabain; Sodium-Potassium-Exchanging ATPase	2010
Formation of new high density glycogen-microtubule structures is induced by cardiac steroids. The Journal of biological chemistry, 2012, Feb-24, Volume: 287, Issue:9 Topics: Adenocarcinoma; Bufanolides; Cardiotonic Agents; Cell Hypoxia; Digoxigenin; Glycogen; Humans; Kidney Neoplasms; MAP Kinase Signaling System; Microscopy, Electron; Microtubules; Neural Stem Cells; Nocodazole; Ouabain; Potassium; RNA, Small Interfering; Sodium-Potassium-Exchanging ATPase; Stress, Physiological; Tubulin Modulators; Tumor Cells, Cultured	2012
Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide. Science (New York, N.Y.), 2013, Jan-04, Volume: 339, Issue:6115 Topics: Cardenolides; Heart Failure; Humans; Ouabain; Oxidation-Reduction	2013
Effect of ouabain on growth of skin explants in organotypic culture. Bulletin of experimental biology and medicine, 2013, Volume: 154, Issue:4 Topics: Animals; Chick Embryo; Ouabain; Skin; Sodium-Potassium-Exchanging ATPase	2013
Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues. Journal of the American Chemical Society, 2015, Jan-28, Volume: 137, Issue:3 Topics: Adrenal Cortex Hormones; Hydroxylation; Molecular Conformation; Ouabain	2015
[The influence of ouabagenin on the growth and proliferation of cells in the organotypical culture]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2014, Volume: 100, Issue:11 Topics: Animals; Cell Proliferation; Chick Embryo; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Sensory; Liver; Myocardium; Ouabain; Retina; Sodium-Potassium-Exchanging ATPase; Tissue Culture Techniques	2014
Cardenolide aglycones inhibit tumor necrosis factor α-induced expression of intercellular adhesion molecule-1 at the translation step by blocking Na⁺/K⁺-ATPase. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:1 Topics: Animals; Cell Line; Cell Line, Tumor; Cell Survival; Digitoxigenin; Digoxigenin; Humans; Intercellular Adhesion Molecule-1; Ouabain; Protein Biosynthesis; Rats; RNA, Messenger; RNA, Small Interfering; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha	2015
Ouabagenin is a naturally occurring LXR ligand without causing hepatic steatosis as a side effect. Scientific reports, 2018, 02-02, Volume: 8, Issue:1 Topics: Diuretics; Fatty Liver; Genes, Reporter; HEK293 Cells; Humans; Liver X Receptors; Luciferases; Molecular Docking Simulation; Ouabain	2018
Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation. Journal of the American Chemical Society, 2019, 03-27, Volume: 141, Issue:12 Topics: Animals; Antineoplastic Agents; Cell Line; Chemistry Techniques, Synthetic; Mice; Ouabain; Oxygen; Stereoisomerism; Structure-Activity Relationship	2019