ouabain and marinobufagenin

ouabain has been researched along with marinobufagenin in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (15.09)	18.2507
2000's	30 (56.60)	29.6817
2010's	13 (24.53)	24.3611
2020's	2 (3.77)	2.80

Authors

Authors	Studies
Anderson, DE; Austin-Lane, JL; Bagrov, AY; Dmitrieva, RI; Fedorova, OV	1
Bagrov, AY; Dmitrieva, RI; Fedorova, OV; Pinaev, AG; Roukoyatkina, NI	1
Anderson, DE; Bagrov, AY; Dmitrieva, RI; Fedorova, OV; French, AW	1
Bagrov, AY; Fedorova, OV	2
Anderson, DE; Bagrov, AY; Fedorova, OV	1
Bagrov, AY; Bagrov, YY; Dmitrieva, NI; Manusova, NB; Patkina, NA; Zvartau, EE	1
Ailamazian, EK; Bagrov, AY; Dmitrieva, RI; Doris, PA; Fedorova, OV; Lopatin, DA; Shpen, VM	1
Bagrov, AY; Fedorova, OV; Lakatta, EG	1
Agalakova, NI; Bagrov, AY; Fedorova, OV; Kolodkin, NI; Lakatta, EG	1
Doris, PA	1
Bagrov, AY; Dorofeeva, NA; Fedorova, OV; Lakatta, EG; Lopatin, DA	1
Bagrov, AY; Fedorova, OV; Gunning, W; Liu, J; Malhotra, D; Periyasamy, SM; Shapiro, JI; Xie, Z	1
Abramowitz, J; Allen, JC; Dai, C; Dmitrieva, RI; Doris, PA; Hirschi, KK; Liu, L	1
Ferrandi, M; Manunta, P	1
Agalakova, NI; Bagrov, AY; Fedorova, OV; Lakatta, EG; Talan, MI	2
Scheiner-Bobis, G; Schoner, W	3
Danchuk, S; Ianosi-Irimie, M; Kamano, Y; Nogawa, T; Pettit, GR; Puschett, JB; Rabon, E; Vu, H; Wiese, T	1
Drabkina, TM; Kravtsova, VV; Krivoĭ, II; Mandel, F; Vasil'ev, AN	1
Amin, MS; Huang, BS; Leenen, FH	1
Komiyama, Y; Takahashi, H	1
Averina, IV; Bagrov, AY; Fedorova, OV; Frolova, EV; Lakatta, EG; Reznik, VA; Tapilskaya, NI	1
Bagrov, AY; Conrady, AO; Kalinkin, AL; Merkulova, NK; Rotari, OP; Shlyakhto, EV; Sviryaev, YV; Zvartau, NE	1
Bagrov, AY; Bagrov, YY; Fedorova, OV; Kashkin, VA; Lakatta, EG; Zvartau, EE	1
Danchuk, S; Glaser, SS; Horvat, D; Mitchell, BM; Morris, CA; Puschett, JB; Sullivan, DE; Uddin, MN	1
Anderson, DE; Bagrov, AY; Fedorova, OV; Kashkin, VA; Lakatta, EG; Longo, DL; Metzler, JD; Morrell, CH	1
Akimova, OA; Hamet, P; Kotelevtsev, SV; Orlov, SN; Poirier, M	1
Glaser, SS; Horvat, D; Mitchell, BM; Puschett, JB; Uddin, MN	1
Chin, KV; El-Okdi, N; Elkareh, J; Fedorova, L; Gupta, S; Kahaleh, MB; Malhotra, D; Periyasamy, S; Raju, V; Shapiro, AP; Shapiro, JI; Shidyak, A; Smaili, S; Xie, Z	1
Brooks, DP; Danoff, TM; Harpel, MR; Pullen, MA	1
Drabkina, TM; Kravtsova, VV; Krivoĭ, II; Kubasov, IV; Prokof'ev, AV; Vasil'ev, AN	1
Bagrov, AY; El-Okdi, N; Fedorova, LV; Fedorova, OV; Giovannucci, DR; Kennedy, DJ; Malhotra, D; Raju, V; Shapiro, JI; Shidyak, A; Vetteth, S	1
Agalakova, NI; Bagrov, AY; Fedorova, OV; Kashkin, VA	1
Bagrov, AY; Fedorova, OV; Lasko, V; Lingrel, JB; Lorenz, JN; Wansapura, AN; Xie, Z	1
Bergold, PJ; Oselkin, M; Tian, D	1
Bagrov, AY; Cooper, CJ; El-Okdi, N; Elkareh, J; Fedorova, OV; Gohara, S; Gupta, S; Haller, S; Malhotra, D; Periyasamy, SM; Shapiro, JI; Shidyak, A; Taleb, M; Tian, J; Xie, Z	1
Bagrov, AY; Bzhelyansky, AM; Fedorova, OV; Frolova, EV; Kashkin, VA; Nikitina, ER; Reznik, VA; Tapilskaya, NI	1
Liu, J; Xie, ZJ	1
Cunha-Filho, G; Noël, F; Pôças, ES; Quintas, LE; Santos, ML; Touza, NA	1
Bagrov, AY; Budny, GV; Fedorova, OV; Frolova, EV; Haller, ST; Isachkina, AN; Kennedy, DJ; Kolmakova, EV; Malhotra, D; Nikitina, ER; Piecha, G; Shapiro, JI	1
Lingrel, JB; Loreaux, EL; Lorenz, JN; Oshiro, N	1
Dai, H; Hertz, L; Li, B; Peng, L; Song, D; Xu, J	1
Allen, SR; Ehrig, JC; Horvat, D; Jones, RO; Kuehl, TJ; Uddin, MN	1
Hamlyn, JM; Manunta, P	1
Anashkina, AA; Klimanova, EA; Lopina, OD; Makarov, AA; Mitkevich, VA; Orlov, SN; Petrushanko, IY	1
Cooper, CJ; Drummond, CA; Fan, X; Garrett, MR; Haller, ST; Hill, MC; Kennedy, DJ; Liu, J; Shapiro, JI; Shi, H; Tian, J; Xie, JX; Xie, Z	1
Andronikashvili, I; Kantaria, N; Pantsulaia, I; Simonia, G	1
Agatisa-Boyle, B; Bagrov, AY; Bucur, P; Conic, J; Fedorova, OV; Hauser, K; Kennedy, DJ; Khalaf, FK; Medert, CM; Sheehy, B; Tang, WHW; Weber, ME; Westfall, K	1
Fedorova, OV; Horesh, N; Ilani, A; Lichtstein, D; Rosen, H; Singh, SV; Wei, W	1
Klimanova, EA; Lopina, OD; Makarov, AA; Mitkevich, VA; Orlov, SN; Petrushanko, IY; Poluektov, YM; Tverskoi, AM	1

Reviews

9 review(s) available for ouabain and marinobufagenin

Article	Year
Abnormalities of sodium pump function in hypertension and the role of endogenous cardiotonic steroids. Cellular and molecular biology (Noisy-le-Grand, France), 2001, Volume: 47, Issue:2 Topics: Absorption; Animals; Blood Pressure; Bufanolides; Cardiac Glycosides; Energy Metabolism; Humans; Hypertension; Kidney; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase	2001
Different effects of marinobufagenin and endogenous ouabain. Journal of hypertension, 2004, Volume: 22, Issue:2 Topics: Animals; Bufanolides; Enzyme Inhibitors; Heart Failure; Humans; Myocardium; Ouabain; Sodium-Potassium-Exchanging ATPase	2004
Endogenous cardiac glycosides: hormones using the sodium pump as signal transducer. Seminars in nephrology, 2005, Volume: 25, Issue:5 Topics: Animals; Blood Pressure; Bufanolides; Cardiac Glycosides; Digoxin; Enzyme Inhibitors; Hormones; Humans; Natriuretic Agents; Ouabain; Signal Transduction; Sodium-Potassium-Exchanging ATPase	2005
The central role of the brain in salt-sensitive hypertension. Current opinion in cardiology, 2006, Volume: 21, Issue:4 Topics: Blood Pressure; Brain; Bufanolides; Calmodulin-Binding Proteins; Cerebrospinal Fluid; Cytochrome P-450 Enzyme System; Endosomal Sorting Complexes Required for Transport; Enzyme Inhibitors; Epithelial Sodium Channels; Humans; Hypertension; Immediate-Early Proteins; Nedd4 Ubiquitin Protein Ligases; Ouabain; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Mineralocorticoid; Receptors, Vasopressin; Renal Insufficiency; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Transcription, Genetic; Ubiquitin-Protein Ligases; Vasoconstrictor Agents	2006
[Endogenous digitalis-like factor]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5 Topics: Animals; Bufanolides; Cardenolides; Epithelial Sodium Channels; Humans; Hypertension; Kidney Tubules; Natriuretic Agents; Ouabain; Saponins; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Vascular Resistance	2006
Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth. American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:2 Topics: Animals; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Bufanolides; Calcium; Cardiac Glycosides; Cardiovascular System; Cell Death; Cell Proliferation; Diabetes Mellitus; Digoxin; Humans; Hypertension; Molecular Structure; Myocardial Contraction; Myocytes, Cardiac; Neoplasms; Ouabain; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship	2007
Role of endogenous cardiotonic steroids in sodium homeostasis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:9 Topics: Adrenal Cortex; Animals; Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Homeostasis; Humans; Hypertension; Kidney Tubules, Proximal; Natriuresis; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents	2008
The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking. Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12 Topics: Animals; Bufanolides; Calcium Signaling; Humans; Hypertension; Kidney Tubules, Proximal; Ouabain; Protein Kinases; Protein Transport; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase	2010
Endogenous cardiotonic steroids in kidney failure: a review and an hypothesis. Advances in chronic kidney disease, 2015, Volume: 22, Issue:3 Topics: Bufanolides; Cardiac Glycosides; Disease Progression; Ganglia, Sympathetic; Humans; Hypertension; Kidney Failure, Chronic; Neuronal Plasticity; Ouabain; Renal Insufficiency, Chronic; Sympathetic Nervous System	2015

Trials

1 trial(s) available for ouabain and marinobufagenin

Article	Year
Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:4 Topics: Adult; Age Factors; Aged; Aging; Blood Pressure; Body Mass Index; Bufanolides; Enzyme Inhibitors; Female; Humans; Hypertension; Linear Models; Middle Aged; Models, Biological; Natriuresis; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Systole; Time Factors; Up-Regulation	2008

Article

Year

Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives.

American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:4

Topics: Adult; Age Factors; Aged; Aging; Blood Pressure; Body Mass Index; Bufanolides; Enzyme Inhibitors; Female; Humans; Hypertension; Linear Models; Middle Aged; Models, Biological; Natriuresis; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Systole; Time Factors; Up-Regulation

2008

Other Studies

43 other study(ies) available for ouabain and marinobufagenin

Article	Year
Endogenous marinobufagenin-like immunoreactive factor and Na+, K+ ATPase inhibition during voluntary hypoventilation. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:5 Topics: Adult; Blood Pressure; Bufanolides; Enzyme Inhibitors; Erythrocytes; Female; Humans; Hypoventilation; Male; Ouabain; Sodium-Potassium-Exchanging ATPase	1995
Effects of two endogenous Na+,K(+)-ATPase inhibitors, marinobufagenin and ouabain, on isolated rat aorta. European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3 Topics: Amphibian Venoms; Animals; Antibodies, Monoclonal; Aorta; Bufanolides; Bufo marinus; Chromatography, Thin Layer; Digitalis Glycosides; Drug Interactions; Female; Immunoassay; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Rats; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents	1995
Plasma marinobufagenin-like and ouabain-like immunoreactivity during saline volume expansion in anesthetized dogs. Cardiovascular research, 1996, Volume: 31, Issue:2 Topics: Animals; Autoantibodies; Bufanolides; Bufo marinus; Cardenolides; Digoxin; Dogs; Fluid Shifts; Immune Sera; Male; Ouabain; Plasma Volume; Saponins; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	1996
Inhibition of Na/K ATPase from rat aorta by two Na/K pump inhibitors, ouabain and marinobufagenin: evidence of interaction with different alpha-subunit isoforms. American journal of hypertension, 1997, Volume: 10, Issue:8 Topics: Animals; Aorta, Thoracic; Blotting, Western; Brain; Bufanolides; Bufo marinus; Enzyme Inhibitors; In Vitro Techniques; Isoenzymes; Kidney; Male; Ouabain; Rats; Rats, Inbred F344; Sodium-Potassium-Exchanging ATPase	1997
Plasma marinobufagenin-like and ouabain-like immunoreactivity in adrenocorticotropin-treated rats. American journal of hypertension, 1998, Volume: 11, Issue:7 Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Body Weight; Bufanolides; Erythrocytes; Heart Rate; Hypertension; Immunoassay; Male; Ouabain; Rats; Rats, Inbred F344; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Systole	1998
Effects of two putative endogenous digitalis-like factors, marinobufagenin and ouabain, on the Na+, K+-pump in human mesenteric arteries. Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2 Topics: Animals; Bufanolides; Digitalis Glycosides; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Male; Mesenteric Arteries; Middle Aged; Ouabain; Protein Conformation; Rats; Sodium-Potassium-Exchanging ATPase; Vasoconstriction	1998
Involvement of endogenous digitalis-like factors in voluntary selection of alcohol by rats. Life sciences, 1999, Volume: 64, Issue:20 Topics: Alcohol Drinking; Animals; Avoidance Learning; Bufanolides; Conditioning, Operant; Digoxin; Ethanol; Freund's Adjuvant; Immunization; Male; Ouabain; Ovalbumin; Rats; Rats, Wistar; Reward; Sodium-Potassium-Exchanging ATPase	1999
Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia. Journal of hypertension, 1999, Volume: 17, Issue:8 Topics: Adult; Animals; Anura; Bufanolides; Cardenolides; Cardiac Glycosides; Chromatography, High Pressure Liquid; Female; Humans; Immunoglobulin Fab Fragments; Ouabain; Pre-Eclampsia; Pregnancy; Sodium-Potassium-Exchanging ATPase; Umbilical Arteries; Vasoconstriction	1999
Endogenous Na,K pump ligands are differentially regulated during acute NaCl loading of Dahl rats. Circulation, 2000, Dec-12, Volume: 102, Issue:24 Topics: Animals; Blood Pressure; Bufanolides; Cardenolides; Digoxin; Electrolytes; Enzyme Inhibitors; Ion Pumps; Male; Ouabain; Potassium; Rats; Rats, Inbred Dahl; Saponins; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	2000
Marinobufagenin, an endogenous alpha-1 sodium pump ligand, in hypertensive Dahl salt-sensitive rats. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Animals; Blood Pressure; Bufanolides; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypertension; Isoenzymes; Kidney; Natriuresis; Ouabain; Rats; Rats, Inbred Dahl; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary	2001
Phorbol diacetate potentiates na(+)-k(+) ATPase inhibition by a putative endogenous ligand, marinobufagenin. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:2 Topics: Animals; Brain; Bufanolides; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Inhibitors; Humans; In Vitro Techniques; Kidney; Male; Mesenteric Arteries; Middle Aged; Ouabain; Phorbol Esters; Rats; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Vasoconstriction	2002
Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells. Kidney international, 2002, Volume: 62, Issue:6 Topics: Animals; Biological Transport; Blood Proteins; Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Dogs; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Kidney Tubules, Distal; Kidney Tubules, Proximal; LLC-PK1 Cells; Ouabain; RNA, Messenger; Rubidium Radioisotopes; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Swine; Uremia	2002
Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5. Circulation, 2003, Dec-16, Volume: 108, Issue:24 Topics: Animals; Bufanolides; Cardiotonic Agents; Cell Division; Cell Line; Cells, Cultured; Enzyme Inhibitors; Female; Humans; Ligands; Muscle, Smooth, Vascular; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase; Umbilical Veins	2003
Coordinated shifts in Na/K-ATPase isoforms and their endogenous ligands during cardiac hypertrophy and failure in NaCl-sensitive hypertension. Journal of hypertension, 2004, Volume: 22, Issue:2 Topics: Animals; Bufanolides; Cardiac Output, Low; Cardiomegaly; Enzyme Inhibitors; Hypertension; Isoenzymes; Ligands; Male; Ouabain; Rats; Rats, Inbred Dahl; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	2004
Brain ouabain stimulates peripheral marinobufagenin via angiotensin II signalling in NaCl-loaded Dahl-S rats. Journal of hypertension, 2005, Volume: 23, Issue:8 Topics: Adrenal Cortex; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Blood Pressure; Brain Chemistry; Bufanolides; Cells, Cultured; Losartan; Male; Natriuresis; Norepinephrine; Ouabain; Pituitary Gland; Rats; Rats, Inbred Dahl; Renin; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents	2005
Resibufogenin corrects hypertension in a rat model of human preeclampsia. Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:2 Topics: Animals; Blood Pressure; Bufanolides; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Hypertension; Isoenzymes; Molecular Structure; Ouabain; Pre-Eclampsia; Pregnancy; Rats; Sodium-Potassium-Exchanging ATPase	2006
[Analysis of the interaction between nicotinic acetylcholine receptor and Na+,K(+)-ATPase in the rat skeletal muscle and the Torpedo electric organ membrane preparation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2006, Volume: 92, Issue:2 Topics: Acetylcholine; Animals; Biological Transport; Bufanolides; Catalysis; Cell Membrane; Dansyl Compounds; Diaphragm; Digoxin; Electric Organ; Erythrocytes; Ligands; Magnesium; Male; Membrane Potentials; Muscle, Skeletal; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Ouabain; Quaternary Ammonium Compounds; Rats; Receptors, Nicotinic; Sodium-Potassium-Exchanging ATPase; Torpedo	2006
Endogenous Na/K-ATPase inhibitors in patients with preeclampsia. Cellular and molecular biology (Noisy-le-Grand, France), 2006, Dec-30, Volume: 52, Issue:8 Topics: Adult; Antibodies; Blood Pressure; Bufanolides; Digoxin; Erythrocytes; Female; Humans; Ouabain; Pre-Eclampsia; Pregnancy; Sodium-Potassium-Exchanging ATPase	2006
Marinobufagenin in hypertensive patients with obstructive sleep apnea. Cellular and molecular biology (Noisy-le-Grand, France), 2006, Dec-30, Volume: 52, Issue:8 Topics: Adult; Blood Pressure Determination; Bufanolides; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Polysomnography; Sleep Apnea, Obstructive	2006
Endogenous bufadienolide mediates pressor response to ethanol withdrawal in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:1 Topics: Animals; Blood Pressure; Bufanolides; Central Nervous System Depressants; Ethanol; Hematocrit; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium; Substance Withdrawal Syndrome; Vasoconstrictor Agents	2008
Marinobufagenin inhibits proliferation and migration of cytotrophoblast and CHO cells. Placenta, 2008, Volume: 29, Issue:3 Topics: Animals; Bufanolides; Cell Adhesion; Cell Movement; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ouabain; Phosphorylation; Sodium-Potassium-Exchanging ATPase; Trophoblasts	2008
The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence. Apoptosis : an international journal on programmed cell death, 2008, Volume: 13, Issue:5 Topics: Amino Acid Chloromethyl Ketones; Animals; Anoikis; Bufanolides; Caspase 3; Caspase Inhibitors; Cell Death; Cell Survival; Cells, Cultured; Chromatin; Dogs; Enzyme Activation; Hydrogen-Ion Concentration; Kidney; Microscopy, Phase-Contrast; Ouabain; Protein Kinase C; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate	2008
Examination of the cellular mechanisms by which marinobufagenin inhibits cytotrophoblast function. The Journal of biological chemistry, 2008, Jun-27, Volume: 283, Issue:26 Topics: Apoptosis; Bufanolides; Caspases; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Interleukin-6; Models, Biological; Ouabain; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Sodium-Potassium-Exchanging ATPase; Trophoblasts	2008
Effects of cardiotonic steroids on dermal collagen synthesis and wound healing. Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:1 Topics: Animals; Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Collagen; Digoxin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Humans; Image Processing, Computer-Assisted; Male; Oligonucleotide Array Sequence Analysis; Ouabain; Proline; Rats; Rats, Sprague-Dawley; Skin; src-Family Kinases; Wound Healing	2008
Comparison of non-digitalis binding properties of digoxin-specific Fabs using direct binding methods. Journal of immunological methods, 2008, Jul-31, Volume: 336, Issue:2 Topics: Antibody Specificity; Antigen-Antibody Reactions; Binding Sites; Binding, Competitive; Bufanolides; Digoxin; Immunoglobulin Fab Fragments; Ouabain	2008
[Effect of nicotine on electrogenic contribution of the Na,K-ATPase isoforms and contractile characteristics of the rat skeletal muscle]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2008, Volume: 94, Issue:10 Topics: Action Potentials; Animals; Bufanolides; Cardiotonic Agents; Male; Muscle Contraction; Muscle, Skeletal; Nicotine; Nicotinic Agonists; Ouabain; Protein Isoforms; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents	2008
The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition. American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:4 Topics: Animals; Bufanolides; Cardiotonic Agents; Cell Movement; Cell Shape; Cell Transdifferentiation; Collagen Type I; Enzyme Inhibitors; Epithelial Cells; Fibronectins; Fibrosis; Infusion Pumps, Implantable; Kidney; Kidney Diseases; LLC-PK1 Cells; Male; Mesoderm; Ouabain; Rats; Rats, Sprague-Dawley; Signal Transduction; Snail Family Transcription Factors; Sodium-Potassium-Exchanging ATPase; Swine; Time Factors; Transcription Factors; Vimentin	2009
Endogenous cardiotonic steroids and differential patterns of sodium pump inhibition in NaCl-loaded salt-sensitive and normotensive rats. American journal of hypertension, 2009, Volume: 22, Issue:5 Topics: Animals; Bufanolides; Cardiac Glycosides; Cyclic GMP; Kidney; Male; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase	2009
Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:6 Topics: Animals; Binding Sites; Bufanolides; Cardiotonic Agents; Dobutamine; Enzyme Activation; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Myocardial Contraction; Ouabain; Sodium-Potassium-Exchanging ATPase; Ventricular Function, Left	2009
Low-dose cardiotonic steroids increase sodium-potassium ATPase activity that protects hippocampal slice cultures from experimental ischemia. Neuroscience letters, 2010, Apr-05, Volume: 473, Issue:2 Topics: Animals; Brain Ischemia; Bufanolides; Cardiotonic Agents; Digoxin; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; In Vitro Techniques; Neuroprotective Agents; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase	2010
Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:6 Topics: Animals; Bufanolides; Canrenone; Cardiomyopathies; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Drug Interactions; Endomyocardial Fibrosis; Fibroblasts; Mineralocorticoid Receptor Antagonists; Myocardium; Nephrectomy; Ouabain; Procollagen; Proline; Rats; Renal Insufficiency; Spironolactone; Tritium; Uremia	2009
Interaction of Digibind with endogenous cardiotonic steroids from preeclamptic placentae. Journal of hypertension, 2010, Volume: 28, Issue:2 Topics: Adult; Binding, Competitive; Bufanolides; Cardiac Glycosides; Case-Control Studies; Cross Reactions; Digoxin; Female; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Kinetics; Ouabain; Placenta; Pre-Eclampsia; Pregnancy	2010
Inhibitory effect of combinations of digoxin and endogenous cardiotonic steroids on Na+/K+-ATPase activity in human kidney membrane preparation. Life sciences, 2011, Jan-03, Volume: 88, Issue:1-2 Topics: Bufanolides; Cardiac Glycosides; Cell Membrane; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Inhibitory Concentration 50; Isoenzymes; Kidney; Ouabain; Sodium-Potassium-Exchanging ATPase	2011
Endogenous cardiotonic steroids in chronic renal failure. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:9 Topics: Animals; Antibodies, Monoclonal; Bufanolides; Case-Control Studies; Chromatography, High Pressure Liquid; Cohort Studies; Digoxin; Erythrocytes; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunoglobulin Fab Fragments; Kidney Failure, Chronic; Male; Middle Aged; Nephrectomy; Ouabain; Oxidative Stress; Prognosis; Prospective Studies; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents	2011
DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase. American journal of hypertension, 2012, Volume: 25, Issue:4 Topics: Animals; Binding Sites; Blood Pressure; Bufanolides; Desoxycorticosterone; Digoxin; Hypertension; Immunoglobulin Fab Fragments; Mice; Myocardial Contraction; Ouabain; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	2012
Ammonia-induced Na,K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling. Neurochemistry international, 2013, Volume: 63, Issue:6 Topics: Ammonia; Animals; Astrocytes; Bufanolides; Cells, Cultured; Enzyme Inhibitors; ErbB Receptors; MAP Kinase Signaling System; Mice; Oncogene Protein v-akt; Ouabain; Phosphatidylinositol 3-Kinases; Phosphorylation; Reactive Oxygen Species; RNA, Small Interfering; Sodium-Potassium-Exchanging ATPase; Swine; Transcriptional Activation	2013
Cardiotonic steroids induce anti-angiogenic and anti-proliferative profiles in first trimester extravillous cytotrophoblast cells. Placenta, 2014, Volume: 35, Issue:11 Topics: Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Cell Proliferation; Cells, Cultured; Female; Humans; Neovascularization, Physiologic; Ouabain; Pregnancy; Pregnancy Trimester, First; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Trophoblasts	2014
Binding of ouabain and marinobufagenin leads to different structural changes in Na,K-ATPase and depends on the enzyme conformation. FEBS letters, 2015, Sep-14, Volume: 589, Issue:19 Pt B Topics: Bufanolides; Enzyme Inhibitors; Hydrolysis; Models, Molecular; Ouabain; Protein Binding; Protein Structure, Tertiary; Sodium-Potassium-Exchanging ATPase; Thermodynamics	2015
Na/K-ATPase signaling regulates collagen synthesis through microRNA-29b-3p in cardiac fibroblasts. Physiological genomics, 2016, Volume: 48, Issue:3 Topics: Animals; Bufanolides; Cardiotonic Agents; Cells, Cultured; Collagen; Down-Regulation; Fibroblasts; Fibrosis; Gene Expression Profiling; Heart Ventricles; Male; MicroRNAs; Myocardium; Nephrectomy; Ouabain; Rats, Sprague-Dawley; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Steroids; Transfection	2016
ASSOSIATION OF ENDOGENOUS CARDIOTONIC STEROIDS WITH SALT-SENSITIVITY OF BLOOD PRESSURE IN GEORGIAN POPULATION. Georgian medical news, 2016, Issue:258 Topics: Blood Pressure; Bufanolides; Cardiac Glycosides; Case-Control Studies; Female; Georgia (Republic); Humans; Hypertension; Male; Ouabain; Sex Factors; Sodium Chloride, Dietary	2016
Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na⁺/K⁺-ATPase Profibrotic Signaling Pathways. International journal of molecular sciences, 2018, Aug-29, Volume: 19, Issue:9 Topics: Animals; Bufanolides; Cell Line; Fibrosis; Glycogen Synthase Kinase 3 beta; Kidney Diseases; MAP Kinase Signaling System; Mice; Ouabain; Phosphorylation; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Swine	2018
Na International journal of molecular sciences, 2020, Aug-17, Volume: 21, Issue:16 Topics: Adult; Bipolar Disorder; Bufanolides; Female; Humans; Male; Middle Aged; Ouabain; Prefrontal Cortex; Protein Isoforms; Sodium-Potassium-Exchanging ATPase	2020
Depth of the Steroid Core Location Determines the Mode of Na,K-ATPase Inhibition by Cardiotonic Steroids. International journal of molecular sciences, 2021, Dec-09, Volume: 22, Issue:24 Topics: Animals; Binding Sites; Bufanolides; Cardiac Glycosides; Digoxin; Hydrogen Bonding; Kidney; Models, Molecular; Ouabain; Protein Binding; Protein Conformation; Rats; Sodium-Potassium-Exchanging ATPase; Swine	2021