ouabain has been researched along with digitoxin in 342 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 285 (83.33) | 18.7374 |
| 1990's | 22 (6.43) | 18.2507 |
| 2000's | 17 (4.97) | 29.6817 |
| 2010's | 14 (4.09) | 24.3611 |
| 2020's | 4 (1.17) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, K; Duax, WL; From, AH; Fullerton, DS; Gilman, TM; Pankaskie, MC; Rohrer, DC | 1 |
| Boutagy, J; Brown, L; Smith, P; Thomas, R | 1 |
| Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A | 1 |
| Bossuyt, X; Hagenbuch, B; Meier, PJ; Müller, M | 1 |
| Ball, WJ; Farr, CD; Fishwild, DM; Nair, AC; Tabet, MR; Wang, X; Welsh, WJ | 1 |
| Abe, M; Abe, T; Chaki, T; Eto, N; Goto, J; Hishinuma, T; Inui, K; Ito, S; Masuda, S; Mikkaichi, T; Mizutamari, H; Okada, M; Onogawa, T; Satoh, F; Suzuki, T; Tanemoto, M; Tokui, T; Unno, M | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Bohlin, L; Felth, J; Fryknäs, M; Gullbo, J; Lindskog, M; Rickardson, L; Rosén, J; Wickström, M | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Arav-Boger, R; Bajaj, SO; Cai, H; Forman, M; Fu, DX; Li, H; O'Doherty, GA; Venkatadri, R; Wang, HY | 1 |
| Byun, SY; Choi, I; Jeon, S; Kim, S; Ko, M; Lee, J; Park, S; Shum, D | 1 |
| Marcus, FI; Ryan, JN; Stafford, MG | 1 |
| Askari, A | 1 |
| Clark, AF; Stahl, WL; Swanson, PD | 1 |
| Lüllmann, H; Peters, T | 2 |
| Akera, T; Brody, TM; Ku, D | 1 |
| Lane, LK | 1 |
| Akera, T; Brody, TM; Gubitz, RH | 1 |
| Engel, H; Proppe, D; Wassermann, O | 1 |
| Akera, T; Brody, TM; Temma, K; Wiest, SA | 1 |
| Marks, MJ; Seeds, NW | 2 |
| Forbush, B; Hoffman, JF | 1 |
| White, SJ; Williamson, K | 1 |
| Kramer, P | 1 |
| Köhler, E; Patnaik, GK | 1 |
| Joubert, P; van der Meer, L | 1 |
| Ghirardi, P; Lombardo, A; Longhini, C; Marzo, A; Musacci, G; Preti, A | 1 |
| Brennan, JK; Gordon, BR; Lichtman, MA; Segel, GB | 1 |
| Glusa, E; Haustein, KO | 1 |
| Dutta, S; Marks, BH; Schoener, EP | 1 |
| Doherty, JE; Kane, JJ | 1 |
| Burns, LB; Stedman, RJ; Tuckerman, MM | 1 |
| Haustein, KO; Richter, M | 1 |
| Ghirardi, P; Lombardo, A; Marzo, A; Preti, A | 2 |
| Rietbrock, N | 1 |
| Flasch, H; Heinz, N | 1 |
| Stickney, JL | 1 |
| Marcus, FI | 1 |
| Rosenberg, HM | 1 |
| Klaassen, CD | 2 |
| Lüllmann, H; Peters, T; Ravens, U | 1 |
| Higuchi, WI; Ho, NF; Shipman, C; Turi, JS | 1 |
| Arbeiter, G; Kötter, V; Kuhlmann, J; Schröder, R; von Leitner, E | 1 |
| Britten, AZ; Njau, E | 1 |
| Doggett, NS | 1 |
| Dale, EM; Dalton, RE; Havemann, DF; Holden, P; Kilgore, WM; Runge, TM; Stephens, JC | 1 |
| Fricke, U; Hollborn, U; Klaus, W | 1 |
| Heinrich, W; Kolassa, N; Pfleger, K; Schneider, M | 1 |
| Skubitz, KM; Smith, TW | 1 |
| Etzold, G; Kammann, G; Megges, R; Prümke, HJ; Scheller, F; Schmidt, HJ | 1 |
| Graumann, G; Haustein, KO; Stephan, B | 1 |
| Fujimoto, S; Iwata, H; Yoneda, Y | 1 |
| Herzig, S; Lilienthal, E; Mohr, K | 1 |
| Bereiter-Hahn, J; Boller, B; Riehle, M | 1 |
| Malhotra, B; Nagappa, AN; Raju, DB; Singh, V; Srivastava, RC | 1 |
| Joubert, PH | 1 |
| Cacini, W; Wernke, MJ | 1 |
| Duncker, G; Herzig, S | 1 |
| Akera, T; Fink, GD; Nirasawa, Y; Temma, K | 1 |
| Swann, AC | 1 |
| Bassin, RH; Benade, LE; deVilliers, J; Hankey, P; Jiang, B; Talbot, N; Yanagihara, K | 1 |
| Midelfart, A | 1 |
| Rhee, HM | 1 |
| Abmann, I; Knappe, J; Lauten, A | 1 |
| Lichtstein, D; Lutz, RA; Rodbard, D; Xu, H | 1 |
| Runge, TM; Shapowal, BL | 1 |
| Osswald, W; Viana, AP | 2 |
| Eickenbusch, W; Lahrtz, H; Seppelt, U; van Zwieten, PA | 1 |
| Gluckman, MI; Triester, S; Yu, DH | 2 |
| Barrillon, A; Gerbaux, A; Lenègre, J; Maurice, P | 1 |
| Est, M; Portius, HJ; Repke, K | 1 |
| Katz, AM | 1 |
| Brown, HD; Chattopadhyay, SK; Patel, A | 1 |
| Lauterbach, F | 2 |
| Albers, RW; Koval, GJ | 1 |
| Datta, DK; Dutta, S; Goswami, S; Lindower, JO; Marks, BH | 1 |
| Kuschinsky, K | 3 |
| Forth, W; Furukawa, E; Rummel, W | 3 |
| Carpenedo, F; Fassina, G; Santi, R | 1 |
| Forth, W; Rummel, W | 2 |
| Hamacher, J; Lüttringhaus, E | 1 |
| Lüllmann, H; Van Zwieten, PA | 2 |
| Reiter, M; Weber, S | 1 |
| Godfraind, T; Lesne, M | 3 |
| Haass, A; Peters, T | 1 |
| Hamacher, J; Kalversiep, G | 1 |
| Kolenda, KD; Peters, T | 1 |
| Kolenda, KD; Peters, T; Seiler, KU | 1 |
| Kawagishi, S | 2 |
| Repke, KR | 1 |
| Abshagen, U; Kewitz, H; Rietbrock, N | 1 |
| Barthel, W; Markwardt, F | 1 |
| Forth, W; Furukawa, E; Leopold, G; Rummel, W | 1 |
| Almendares, JA; Kleinzeller, A | 1 |
| Brooker, G; Jelliffe, RW | 1 |
| Smith, TW | 3 |
| Daniel, EE; Kidwai, AM; Murthy, RV | 3 |
| Kuschinsky, K; Rieger, J | 1 |
| Braun, W; Damm, KH; Heckert, H | 1 |
| Godfraind, T | 2 |
| De Pover, A; Godfraind, T | 1 |
| Belz, G; Belz, GG; Brech, WJ; Kleeberg, UR; Rudofsky, G | 1 |
| Fujimoto, JM; Smith, DS | 1 |
| Belz, GG; Kurbjuweit, HG; Oberdorf, A; Stauch, GB | 1 |
| Barthel, W; Haustein, KO; Markwardt, F | 1 |
| Hauptmann, J; Haustein, KO | 1 |
| Brassel, G; Lange-Asschenfeldt, H | 1 |
| Fricke, U; Klaus, W | 1 |
| Alexander, DR | 1 |
| Bhat, HB; Brar, S; Dutta, S; Marks, BH; Rhee, HM; Richards, SR; Zavecz, JH | 1 |
| Akera, DK; Brody, TM; Ku, D; Pew, CL | 1 |
| Kypson, J; Nahas, GG; Triner, L | 1 |
| Fawaz, G | 1 |
| Hoffman, BF; Ross, SM; Ten Eick, RE; Wyte, SR | 1 |
| van Zwieten, PA | 1 |
| Damm, KH; Woermann, C | 1 |
| Afifi, AM; Ammar, EM | 1 |
| Damm, KH; Erttmann, R | 1 |
| Moffat, AC | 1 |
| Lavrova, EA; Natochin, YV | 1 |
| Kimmich, GA | 1 |
| Haber, E; Smith, TW | 1 |
| Elenbaas, RM; Kimble, MA | 1 |
| Bulter, VP; Gardner, JD; Schmidt, DH; Watson, JF | 1 |
| Haass, A; Lüllmann, H; Peters, T | 1 |
| Budihna, M; Weber, WV | 1 |
| Beigelman, PM; Thomas, LJ | 1 |
| Förster, W; Mentz, P; Witzleben, H | 1 |
| Ohlmeier, H; Ruiz-TOrres, A | 1 |
| Gross, DR; Hamlin, RL; Pipers, FS | 2 |
| Klaassen, CD; Russell, JQ | 1 |
| Böhm, A | 1 |
| Fortmüller, HW; Greeff, K; Köhler, E; Schmidt, R | 1 |
| Gillilan, RM; Lanman, RC; Schanker, LS | 1 |
| Ghirardi, P; Marchetti, G; Marzo, A; Matteoli, E; Riva, D; Zaini, G | 1 |
| Anselmi, E; Bolufer, J; Larralde, J | 1 |
| Köthe, E; Kramer, P; Scheler, F | 1 |
| Bernsmeier, A | 1 |
| Alken, RG; Fricke, U; Klaus, W | 1 |
| Fukuda, T | 1 |
| Repke, K | 1 |
| Doherty, JE | 1 |
| Haas, H | 1 |
| Lüllmann, H; Peters, T; Seiler, KU | 1 |
| Ruiz-Torres, A | 1 |
| Dutta, S; Marks, BH; Rhee, HM | 1 |
| Weiss, L | 1 |
| Mayhew, E | 1 |
| Greeff, K; Köhler, E; Noack, E; Wirth, K | 1 |
| Vergassola, R | 1 |
| Eguchi, N | 1 |
| Bergmann, F; Gutman, Y; Zerachia, A | 1 |
| Fujino, S; Izumi, T; Kawagishi, S; Tanaka, M | 1 |
| Dutta, S; Marks, BH | 1 |
| Mécs, I; Selye, H; Tamura, T | 1 |
| Greeff, K; Greven, G; Osswald, W; Viana, AP | 1 |
| Horenkamp, J; Kramer, P; Scheler, F; Willms, B | 2 |
| Godfriand, T; Lesne, M | 1 |
| Caldwell, JH; Greenberger, NJ; Halpin, TC | 1 |
| Haddow, JE; Klein, R | 1 |
| Gisvold, O; Ishaq, KS | 1 |
| Dutta, S; Hollander, PB; Ito, M; Marks, BH | 1 |
| Bergmann, F; Chaimovitz, M; Costin, A; Zerachia, A | 1 |
| Förster, W; Pfordte, K | 1 |
| Berger, JM; Dookhoo, A; Eu, HY; Melville, KI | 1 |
| Lenke, D; Schneider, B | 2 |
| Burstein, S; Griffin, CL; Pendleton, R | 1 |
| Kolenda, KD; Lüllmann, H; Peters, T; Seiler, KU | 1 |
| Kolenda, KD; Lüllmann, H; Peters, T | 1 |
| Parsons, JA; Summers, RJ | 1 |
| Reiter, M | 1 |
| Halle, W | 1 |
| Kuschinsky, K; Lüllmann, H; van Zwieten, PA | 3 |
| Kupferberg, HJ; Schankl, LS | 1 |
| Lüllmann, H; Weber, R | 1 |
| Lahrtz, H; Sattler, RW; van Zwieten, PA | 1 |
| Klingner, B; Melville, KI; Shister, HE | 1 |
| Natorp, W; Schultz, U | 1 |
| Garbe, A; Nowak, H | 1 |
| Lüllmann, H; Peters, T; van Zwieten, PA | 1 |
| Lüllmann, H; van Zwieten, PA; Weber, R | 1 |
| Contarini, M; Cospito, M; Gangemi, G | 1 |
| Menge, HG | 1 |
| McLain, PL | 1 |
| Csáky, TZ; Hara, Y | 1 |
| Furukawa, T | 1 |
| Grauwiler, J; Schalch, WR; Taeschler, M | 1 |
| Förster, W; Popov, N | 1 |
| Förster, W; Grade, K; Rösler, V | 1 |
| Rosenkranz, H; Schlossmann, K; Scholtan, W | 1 |
| Levitt, B; Roberts, J | 1 |
| Jaskiewicz, G; Samochowiec, L | 1 |
| Bianchi, C | 1 |
| Becker, BA; Gibson, JE | 1 |
| Churchill, L; Hall, CC; Hokin, LE; Peterson, GL; Ruoho, AE | 1 |
| Hall, C; Ruoho, A | 1 |
| Akera, T; Brody, TM; Kondo, H; Temma, K | 1 |
| Brown, L; Erdmann, E | 2 |
| Brown, L; Erdmann, E; Thomas, R | 1 |
| Brandt, NR; Brunschwig, JP; Caswell, AH | 1 |
| Mohr, K | 1 |
| Ayachi, S; Brown, AM | 1 |
| Remmer, H; Schwenk, M; Wiedmann, T | 1 |
| Schwenk, M | 1 |
| Bereiter-Hahn, J; Riehle, M | 1 |
| Burks, EA; Chen, G; Georgiou, G; Iverson, BL | 1 |
| Kakimoto, S; Matsuki, N; Saito, H | 1 |
| Kintz, P; Ludes, B; Mangin, P; Tracqui, A | 1 |
| Del Bene, P; Paci, A; Sakakibara, M; Uchida, AO | 1 |
| Fukuo, K; Hirotani, A; Kitano, S; Morimoto, S; Nakahashi, T; Nishibe, A; Ogihara, T; Yasuda, O | 1 |
| Chen, G; Dubrawsky, I; Georgiou, G; Iverson, BL; Mendez, P | 1 |
| Hwang, JJ; Lin, H; Wang, PS; Wang, SW | 1 |
| Barbehenn, RV | 1 |
| Hamilton, BP; Hamilton, J; Hamlyn, JM; Manunta, P; Rogowski, AC | 1 |
| Chen, JJ; Chien, EJ; Wang, PS; Wang, SW | 1 |
| Izumi-Kurotani, A; Naitoh, T; Takabatake, I; Wassersug, RJ; Yamashita, M | 1 |
| Huang, WJ; Kan, SF; Wang, PS; Yeh, JY | 1 |
| Chen, JJ; Chien, EJ; Wang, PS | 1 |
| Meijer, DK; van Monffoort, JE | 1 |
| REINERT, H | 2 |
| ACHESON, GH; KAHN, JB; VICK, RL | 1 |
| RAND, M; STAFFORD, A | 1 |
| HOUK, AE | 1 |
| MICKATAVAGE, RC; SMITH, JL | 1 |
| MUELLER, P | 1 |
| UCHIDA, S | 1 |
| ERLIJ, D; MENDEZ, R | 1 |
| DOWBEN, RM; GORDON, P; SNIDERMAN, SP; ZUCKERMAN, L | 1 |
| ACHESON, GH; KAHN, JB; LIPICKY, RJ | 1 |
| KURBJUWEIT, HG | 1 |
| CHAO, HB; HUANG, MM; KIANG, MS | 1 |
| WHONG, H; WONG, CK; YEAU, KL | 1 |
| MURASE, H | 1 |
| Fernández, P; Núñez-Durán, H | 1 |
| Kan, SF; Lo, MJ; Pu, HF; Tseng, CI; Wang, PS; Wang, SW | 1 |
| Chen, MJ; Chow, YC; Hsu, JM; Huang, HL; Lin, CW; Pu, HF; Tseng, CI; Wang, PS; Wang, SW | 1 |
| Gill, R; Gill, S; Liang, S | 1 |
| Geerts, A; Kolkhof, P; Schäfer, S; Torzewski, J | 1 |
| Chang, PL; Juang, HH; Lin, YF; Tsui, KH | 1 |
| FARAH, A | 1 |
| Arav-Boger, R; Cai, H; Forman, M; He, R; Kapoor, A; Shamay, M | 1 |
| Arav-Boger, R; Cai, H; Forman, M; He, R; Kapoor, A; Posner, GH; Venkatadri, R | 1 |
| Burke, SD; Cerdeira, AS; Geahchan, C; George, EM; Granger, JP; Karumanchi, SA; Rajakumar, A; Rana, S; Salahuddin, S | 1 |
| Chan, WI; Feng, Q; Leong, WS; Liu, L | 1 |
| Cho, YY; Choi, JS; He, N; Jeon, SM; Jeong, E; Kim, JH; Kim, N; Kim, S; Kim, WY; Lee, CJ; Lee, HS; Mills, GB; Song, M; Yim, HY; Yoon, S | 1 |
| Folts, CJ; Gao, X; Jiang, M; Lan, X; Lin, S; Liu, K; Lu, R; Noble, MD; Que, J; Zhang, Y; Zhao, T; Zhou, Z | 1 |
| Bejček, J; Pavlíčková, VS; Rimpelová, S; Škubník, J | 1 |
| Bera, A; Caohuy, H; Chen, T; Eidelman, O; Liu, S; Pollard, HB; Walton, NI; Wang, TT; Yang, Q | 1 |
| Ferreira, RS; Qayed, WS; Silva, JRA | 1 |
| Beasley, AB; Kelliher, GJ; Lathers, CM; Roberts, J | 1 |
| Ikeda, M; Miyamori, I; Morise, T; Okamoto, S; Takeda, R | 1 |
| Neely, JR; Tani, M | 1 |
| Andersson, TL; Vinge, E; Zygmunt, P | 1 |
| Eilam, Y; Hallaq, H; Heller, M; Panet, R | 1 |
| Balzan, S; Biver, P; Gazzetti, P; Ghione, S; Montali, U | 1 |
| Bose, D; Chan, TL; Chau, TC | 1 |
| Kuske, R; Moreth, K; Renner, D; Schoner, W; Wizemann, V | 1 |
| Halperin, JA | 1 |
| Masuyama, Y; Shima, H; Tsuda, K; Tsuda, S | 1 |
| Lazdunski, M; Rossi, B | 1 |
| Canessa, ML; Kelly, RA; Mitch, WE; O'Hara, DS; Smith, TW | 1 |
| Brent, D; Gault, MH; Johnson, E; Longerich, L; Vasdev, S | 1 |
| Dresel, PE; Ogbaghebriel, A | 1 |
| El-Sherif, N; Gough, WB; Hariman, RJ; Zeiler, RH | 1 |
| Cloix, JF; Crabos, M; Deray, G; Devynck, MA; Meyer, P; Pernollet, MG; Rieu, M; Wainer, IW | 1 |
| Allen, JC; Schwartz, A | 2 |
| Lindenmayer, GE; Schwartz, A | 1 |
| Cohen, SN; Doyle, EF; Rutkowski, MM | 1 |
| Okita, GT; Richardson, F; ten Eick, RE | 1 |
| Kones, RJ | 1 |
| Langer, GA; Serena, SD | 1 |
| Amsterdam, EA; Mason, DT; Massumi, RA; Zelis, R | 1 |
| Atkinson, AJ; Davison, R | 1 |
| Engel, TR; Schaal, SF | 1 |
| Arbeit, S; Delman, AJ; Escher, JW | 1 |
| Levitt, B; Raines, A; Sohn, YJ; Standaert, FG | 1 |
| Levitt, B; Moros, D; Raines, A; Standaert, FG | 1 |
| Cotten, MD; Moore, JI | 1 |
| Hansen, O | 1 |
| Baudouin-Legros, M; Cloix, JF; Crabos, M; Delva, P; Deray, G; Devynck, MA; Henning, G; Pernollet, MG; Rieu, M; Wauquier, I | 1 |
| Adams, RJ; Grupp, G; Grupp, I; Lee, SW; Schwartz, A; Whitmer, K | 1 |
| Cloix, JF; Devynck, MA; Kamal, LA; Meyer, P | 1 |
| Lazdunski, M; Ponzio, G; Rossi, B | 1 |
| Burgersdijk, C; van der Meer, FJ; van der Vijver, JC | 1 |
| Floreani, M; Luciani, S | 1 |
| Erdmann, E; Krawietz, W; Werdan, K | 1 |
| Agarwal, JB; Banka, VS; Bodenheimer, MM; Helfant, RH; Yamazaki, H | 1 |
| Grupp, G; Grupp, IL; Schwartz, A | 1 |
| Graves, SW; Hollenberg, NK; Soszynski, PA; Tao, QF | 1 |
| Berson, D; Deutsch, J; Gati, I; Landau, L; Lichtstein, D; Rozenman, Y; Samuelov, S | 1 |
| Bagrov, A; Carter, P; Chen, J; Cooney, D; Fedorova, O; Malhotra, D; Omran, E; Periyasamy, SM; Priyadarshi, S; Shapiro, JI; Tian, J; Xie, Z | 1 |
| TYRER, JH | 1 |
| MEIER, R; SCHULER, W; TRIPOD, J | 1 |
| ABAOGLU, C | 1 |
| NAYLER, WG | 1 |
| RAYNER, B; WEATHERALL, M | 1 |
| MACREZ, C; MOUQUIN, M | 1 |
| BRAUNWALD, E; BROCKENBROUGH, EC; FRYE, RL | 1 |
| CATTANEO, F; MARINI, A; SERENI, F; VISCONTIDIMASSINO, U | 1 |
| BRAUNWALD, E; MASON, DT | 1 |
| EL-FIKY, SB; KATZUNG, BG | 1 |
| HERENDEEN, T; WALDHAUSEN, JA | 1 |
| BORISON, HL; GAITONDE, BB; MCCARTHY, LE | 1 |
| BOYAJY, LD; NASH, CB | 1 |
| NISHIJIMI, N | 1 |
| Balke, CW; Blaustein, MP; Gottlieb, SS; Hamlyn, JM; Robinson, SW | 1 |
| Lichtstein, D; Nesher, M; Rosen, H; Shpolansky, U | 1 |
| RISING, JD | 1 |
| WOLLENBERGER, A | 1 |
| Abdallah, SL; Askari, A; Gable, ME; Liu, L; Najjar, SM | 1 |
| Takahashi, H | 1 |
26 review(s) available for ouabain and digitoxin
| Article | Year |
|---|---|
Digitalis pharmacokinetics and therapy with respect to impaired renal function.
Topics: Cardiac Glycosides; Digitoxin; Digoxin; Drug Tolerance; Glomerular Filtration Rate; Humans; Kidney Diseases; Kinetics; Ouabain; Protein Binding; Renal Dialysis; Strophanthins; Uremia | 1977 |
Digitalis pharmacokinetics and metabolism.
Topics: Atrial Fibrillation; Creatinine; Delayed-Action Preparations; Digitalis Glycosides; Digitoxin; Digoxin; Electrocardiography; Feces; Half-Life; Heart Failure; Humans; Kidney; Kinetics; Ouabain; Time Factors | 1975 |
Are all cardiac glycosides pharmacodynamically similar?
Topics: Animals; Cardiac Output, Low; Digitalis Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Heart Rate; Humans; Muscle Contraction; Ouabain | 1990 |
Contribution of quantitative assay technics to the understanding of the clinical pharmacology of digitalis.
Topics: Adenosine Triphosphatases; Animals; Autoradiography; Biological Assay; Chromatography, Gas; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Ducks; Erythrocytes; Humans; Ouabain; Phenobarbital; Phenylbutazone; Potassium; Radioimmunoassay; Radioisotope Dilution Technique; Radioisotopes; Rubidium; Sodium | 1972 |
[Pharmacology of digitalis receptors].
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Biological Transport, Active; Calcium; Cardiac Glycosides; Cell Membrane; Digitoxin; Digoxin; Guinea Pigs; Heart Atria; Microsomes; Muscle Contraction; Muscle, Smooth; Norepinephrine; Ouabain; Receptors, Drug; Sodium; Tritium | 1972 |
Cardiac glycosides and contractility.
Topics: Adenosine Triphosphatases; Animals; Calcium; Calcium Radioisotopes; Digitoxin; Guinea Pigs; Half-Life; Ouabain; Papillary Muscles; Tritium | 1974 |
The kinetic behaviour of cardiac glycosides in vivo, measured by isotope techniques.
Topics: Animals; Carbon Isotopes; Cardiac Glycosides; Digitoxin; Guinea Pigs; Heart Atria; Humans; In Vitro Techniques; Kidney; Kinetics; Liver; Myocardium; Ouabain; Rabbits; Receptors, Drug; Tritium | 1969 |
Digitalis glycosides. I.
Topics: Arrhythmias, Cardiac; Biopharmaceutics; Digitalis Glycosides; Digitoxin; Digoxin; Half-Life; Heart; Humans; Lanatosides; Ouabain; Structure-Activity Relationship; Vascular Resistance | 1973 |
Coupling between Na+ and sugar transport in small intestine.
Topics: Amino Acids; Animals; Biological Transport; Biological Transport, Active; Cations, Monovalent; Digitoxin; Epithelium; Galactose; Glucose; Glycosides; Intestine, Small; Kinetics; Membrane Potentials; Models, Biological; Monosaccharides; Nitrophenols; Ouabain; Potassium; Potentiometry; Sodium | 1973 |
Digitalis (third of four parts).
Topics: Adult; Age Factors; Animals; Biopharmaceutics; Cardanolides; Cardiac Glycosides; Child; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Half-Life; Humans; Infant; Kinetics; Lanatosides; Ouabain; Plants, Medicinal; Plants, Toxic; Radioimmunoassay; Time Factors | 1973 |
Congestive heart failure.
Topics: Age Factors; Creatinine; Diet; Digitalis; Digitalis Glycosides; Digitoxin; Digoxin; Diuretics; Heart Failure; Humans; Hypercalcemia; Hypokalemia; Kidney; Kinetics; Liver; Magnesium; Ouabain; Plants, Medicinal; Plants, Toxic; Rest; Thyroid Gland; Time Factors | 1974 |
Production and properties of digoxin-specific antibodies.
Topics: Animals; Antibodies; Antibody Formation; Arrhythmias, Cardiac; Biological Assay; Cattle; Cross Reactions; Digitoxin; Digoxin; Dogs; Immunoglobulin G; Ouabain; Papain; Protein Binding; Rabbits; Serum Albumin, Bovine; Sheep; Species Specificity; Structure-Activity Relationship; Time Factors; Tritium | 1974 |
The clinical pharmacology of digitalis glycosides: a review.
Topics: Blood Urea Nitrogen; Carbon Isotopes; Digitalis Glycosides; Digitoxin; Digoxin; Feces; Humans; Lanatosides; Ouabain; Tritium | 1968 |
[Scillaglycosides].
Topics: Animals; Cardanolides; Cardiac Glycosides; Digitoxin; Digoxin; Dogs; Guinea Pigs; Humans; Ouabain; Potassium; Rats; Strophanthins | 1967 |
[Metabolism and intestinal absorption of cardiac glycosides].
Topics: Animals; Cardanolides; Cardiac Glycosides; Digitoxin; Digoxin; Humans; Intestinal Absorption; Intestinal Mucosa; Ouabain; Rats | 1969 |
A pharmacological approach to the mode of digitalis action.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Biological Transport; Cardiac Glycosides; Catecholamines; Chemoreceptor Cells; Digitalis Glycosides; Digitoxin; Digoxin; Drug Synergism; Epinephrine; Guinea Pigs; Heart; Histamine Antagonists; Humans; Hydrogen-Ion Concentration; Muscle, Smooth; Neuroeffector Junction; Ouabain; Rats; Temperature | 1969 |
[Distribution and biotransformation of various cardiac glycosides].
Topics: Animals; Biotransformation; Cardiac Glycosides; Cell Membrane Permeability; Digitoxin; Digoxin; Guinea Pigs; Heart; Humans; Intestinal Absorption; Liver; Myocardium; Ouabain; Protein Binding; Strophanthins; Tritium | 1971 |
[Kinetics of cardiac steroids in man and experimental animals].
Topics: Adrenal Glands; Animals; Cardiac Glycosides; Cats; Digitalis Glycosides; Digitoxin; Digoxin; Dogs; Heart; Humans; Kidney; Kinetics; Lanatosides; Liver; Myocardium; Ouabain; Rats; Species Specificity; Strophanthins; Tritium | 1970 |
Repurposing Cardiac Glycosides: Drugs for Heart Failure Surmounting Viruses.
Topics: Antiviral Agents; Cardiac Glycosides; COVID-19; Digitoxin; Digoxin; Drug Repositioning; Heart Failure; Humans; Neoplasms; Ouabain; Pandemics; SARS-CoV-2; Sodium-Potassium-Exchanging ATPase; Virus Internalization; Virus Replication | 2021 |
Cardiogenic shock. Recent advances in pharmacologic management. II.
Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Catecholamines; Cyclic AMP; Depression, Chemical; Digitalis; Digitalis Glycosides; Fatty Acids, Nonesterified; Glucagon; Glucocorticoids; Growth Hormone; Humans; Insulin; Isoproterenol; Metaraminol; Methoxamine; Myocardial Infarction; Norepinephrine; Ouabain; Oxygen Consumption; Phosphoric Diester Hydrolases; Plants, Medicinal; Plants, Toxic; Shock, Cardiogenic; Stimulation, Chemical | 1973 |
The digitalis glycosides: contractile and electrophysiologic actions, clinical indications, precautions, and toxicity.
Topics: Action Potentials; Adult; Aged; Arrhythmias, Cardiac; Cardiac Output; Cardiac Volume; Digitalis; Digitalis Glycosides; Digoxin; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Male; Membrane Potentials; Middle Aged; Mitochondria, Muscle; Muscle Contraction; Ouabain; Plants, Medicinal; Plants, Toxic; Refractory Period, Electrophysiological; Sarcoplasmic Reticulum; Stimulation, Chemical | 1972 |
Diphenylhydantoin as an antiarrhythmic drug.
Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Catheterization; Cardiac Surgical Procedures; Coronary Disease; Depression, Chemical; Digitalis; Digoxin; Heart; Heart Diseases; Humans; Injections, Intravenous; Ouabain; Phenytoin; Plants, Medicinal; Plants, Toxic; Ventricular Fibrillation | 1974 |
Interaction of cardiac glycosides with (Na+ + K+)-activated ATPase. A biochemical link to digitalis-induced inotropy.
Topics: Adenosine Triphosphate; Animals; Cardiac Glycosides; Digitalis; Humans; Kinetics; Ligands; Magnesium; Myocardial Contraction; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Protein Conformation; Receptors, Drug; Sodium; Sodium-Potassium-Exchanging ATPase; Vanadates; Vanadium | 1984 |
Sex, digitalis, and the sodium pump.
Topics: Animals; Clinical Trials as Topic; Digitalis; Digitalis Glycosides; Digoxin; Female; Heart Failure; Hormone Replacement Therapy; Humans; Male; Ouabain; Sex Factors; Sodium-Potassium-Exchanging ATPase | 2003 |
The digitalis-like steroid hormones: new mechanisms of action and biological significance.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Digitalis; Endocytosis; Humans; Ions; Models, Biological; Natriuretic Agents; Ouabain; Plant Extracts; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Steroids | 2007 |
[Laboratory Medicine Learned Through Research on the Pathogenesis of Hypertension].
Topics: Animals; Baroreflex; Central Nervous System; Digitalis; Epithelial Sodium Channels; Humans; Hyperaldosteronism; Hypertension; Kidney; Medical Laboratory Science; Obesity; Ouabain; Renin-Angiotensin System; Research; Sodium, Dietary; Sympathetic Nervous System | 2015 |
3 trial(s) available for ouabain and digitoxin
| Article | Year |
|---|---|
Pharmacological investigation on asclepin--a new cardenolide from Asclepias curassavica. Part II. Comparative studies on the inotropic and toxic effects of asclepin, g-strophantin, digoxin and digitoxin).
Topics: Animals; Blood Pressure; Cardenolides; Cardiac Glycosides; Cats; Clinical Trials as Topic; Digitoxigenin; Digitoxin; Digoxin; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Time Factors | 1978 |
Serum cardiac glycoside assay based upon displacement of 3 H-ouabain from Na-K ATPase.
Topics: Adenosine Triphosphatases; Animals; Arrhythmias, Cardiac; Binding Sites; Brain; Cardiac Glycosides; Chemistry, Clinical; Clinical Trials as Topic; Digitalis Glycosides; Digitoxin; Digoxin; Guinea Pigs; Humans; Immunoassay; Methods; Ouabain; Potassium; Radionuclide Imaging; Sodium; Tritium; Tromethamine | 1972 |
Influence of digitalis and diuretics on ouabain binding sites on human erythrocytes.
Topics: Adult; Binding Sites; Digitalis; Diuretics; Erythrocytes; Humans; Ouabain; Plants, Medicinal; Plants, Toxic | 1984 |
313 other study(ies) available for ouabain and digitoxin
| Article | Year |
|---|---|
Cardenolide analogues. 2. 22-Methylenecard-14-enolides.
Topics: Adenosine Triphosphatases; Animals; Brain; Cardenolides; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Rats; Stereoisomerism; Structure-Activity Relationship | 1977 |
Cardenolide analogues. 14. Synthesis and biological activity of glucosides of C17 beta-modified derivatives of digitoxigenin.
Topics: Animals; Chemical Phenomena; Chemistry; Digitalis Glycosides; Digitoxigenin; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardial Contraction | 1982 |
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors | 1980 |
Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver.
Topics: Aldosterone; Animals; Anions; Gene Expression; Ion Transport; Liver; Oocytes; Ouabain; Peptides; Steroids; Time Factors | 1996 |
Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Binding, Competitive; Carbohydrate Sequence; Digoxin; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin Fab Fragments; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Ouabain; Progesterone; Quantitative Structure-Activity Relationship; Radioligand Assay | 2002 |
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Digoxin; DNA, Complementary; Dogs; Female; Humans; Kidney; Kinetics; Male; Molecular Sequence Data; Organic Anion Transporters; Phylogeny; Rats; Recombinant Proteins; Renal Insufficiency; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Transfection | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cardenolides; Colonic Neoplasms; Digitoxin; Digoxin; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Irinotecan; NF-kappa B; Proscillaridin; Strophanthins | 2009 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Digitoxin analogues with improved anticytomegalovirus activity.
Topics: | 2014 |
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs.
Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Niclosamide; Pandemics; Pneumonia, Viral; Pregnenediones; SARS-CoV-2; Vero Cells | 2020 |
The reactivity of derivatives of digoxin and digitoxin as measured by the Na-K-atpase displacement assay and by radioimmunoassay.
Topics: Adenosine Triphosphatases; Animals; Digitalis Glycosides; Digitoxin; Digoxin; Humans; Immune Sera; Ouabain; Potassium; Radioimmunoassay; Sheep; Sodium | 1975 |
Red cell Na+,K+-ATPase: a method for estimating the extent of inhibition of an enzyme sample containing an unknown amount of bound cardiac glycoside.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Cardiac Glycosides; Cell Membrane; Depression, Chemical; Digitoxin; Digoxin; Erythrocytes; Humans; Magnesium; Methods; Ouabain; Potassium; Regeneration; Sodium | 1975 |
Increase in dissociation rate constants of cardiotonic steroid-brain (Na+ + K+)-ATPase complexes by reduction of the unsaturated lactone.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Cardiac Glycosides; Cattle; Cerebral Cortex; Cymarine; Digitoxigenin; Digitoxin; Digoxin; Enzyme Activation; Kinetics; Lactones; Microsomes; Ouabain; Oxidation-Reduction; Potassium; Protein Binding; Sodium; Strophanthidin; Structure-Activity Relationship | 1975 |
On the sarcolemmal site of action of cardiac glycosides.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Calcium; Cell Membrane; Digitoxin; Digoxin; Enzyme Activation; Guinea Pigs; Inulin; Microscopy, Electron; Myocardium; Ouabain; Potassium; Sarcolemma; Sodium; Sucrose; Swine | 1976 |
Cardiac glycosides: relationship among active 86Rb uptake, (Na+,K+)-ATPase activity, and inotropy in guinea pig heart.
Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Digitoxin; Guinea Pigs; Heart; Myocardial Contraction; Myocardium; Ouabain; Potassium; Rubidium; Sodium | 1976 |
Gel chromatography and gel electrophoresis of cardiac glycoside-Na,K-ATPase complexes in sodium dodecyl sulfate: a caution.
Topics: Adenosine Triphosphatases; Chromatography, Gel; Dialysis; Digitoxin; Electrophoresis, Polyacrylamide Gel; Myocardium; Ouabain; Protein Binding; Receptors, Drug; Sodium Dodecyl Sulfate | 1976 |
Control of brain slice respiration by (Na+ + K+)-activated adenosine triphosphate and the effects of enzyme inhibitors.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Membrane; Cerebral Cortex; Chlorpromazine; Choline; Digitoxin; Dinitrophenols; Enzyme Activation; Glucose; In Vitro Techniques; Male; Ouabain; Oxygen Consumption; Potassium; Pyruvates; Rats; Sodium | 1977 |
Influence of highly unsaturated phosphatidylcholine on the effects of ouabain and some cardioactive drugs on cardiac contractile force and Na+, K+-ATPase activity.
Topics: Acetylcholine; Adenosine Triphosphatases; Animals; Calcium; Cattle; Digitoxin; Digoxin; Enzyme Activation; Female; Guinea Pigs; Isoproterenol; Kinetics; Male; Myocardial Contraction; Myocardium; Ouabain; Pentobarbital; Phosphatidylcholines; Potassium; Sodium | 1977 |
Reduction of the equilibrium binding of cardiac glycosides and related compounds to Na+,K+-ATPase as a possible mechanism for the potassium-induced reversal of their toxicity.
Topics: Animals; Cardiac Glycosides; Digitoxigenin; Digitoxin; Dogs; In Vitro Techniques; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Time Factors | 1978 |
A heterogeneous ouabain-ATPase interaction in mouse brain.
Topics: Animals; Brain; Digitoxin; Drug Interactions; In Vitro Techniques; Kidney; Kinetics; Mice; Mice, Inbred C57BL; Ouabain; Sodium-Potassium-Exchanging ATPase | 1978 |
Ouabain-ATPase interaction in brain cells maintained as reaggregates or surface cultures.
Topics: Brain; Cells, Cultured; Digitoxin; Drug Interactions; Kinetics; Ouabain; Radioisotopes; Rubidium; Sodium-Potassium-Exchanging ATPase | 1978 |
Direct photoaffinity labeling of the primary region of the ouabain binding site of (Na+ + K+)-ATPase with [3H]ouabain, [3H]digitoxin and [3H]digitoxigenin.
Topics: Affinity Labels; Binding Sites; Digitoxigenin; Digitoxin; Kinetics; Ouabain; Photolysis; Protein Binding; Sodium-Potassium-Exchanging ATPase | 1979 |
What to watch for when you give digitalis.
Topics: Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Humans; Ouabain | 1979 |
A specific cardiac glycoside for cardiac failure and another for atrial fibrillation?
Topics: Animals; Atrioventricular Node; Digitoxin; Dose-Response Relationship, Drug; Drug Synergism; Electrocardiography; Female; Heart Conduction System; Male; Myocardial Contraction; Ouabain; Propranolol; Rats; Stimulation, Chemical; Time Factors; Vagotomy | 1979 |
Subcellular distribution of deslanatoside C, ouabain and digitoxin in the heart and liver of conscious guinea pigs.
Topics: Animals; Blood Proteins; Deslanoside; Digitoxin; Guinea Pigs; Lanatosides; Liver; Male; Myocardium; Ouabain; Protein Binding; Subcellular Fractions; Time Factors | 1977 |
Effect of molecular modification on the inhibition of lymphocyte blastogenesis by cardiac glycosides.
Topics: Animals; Cardiac Glycosides; Cats; Cell Survival; Cells, Cultured; Digitoxin; Digoxin; DNA; Humans; Lymphocyte Activation; Molecular Conformation; Ouabain; Thymidine; Time Factors | 1978 |
Kinetic properties of 3H-16alpha-gitoxin in the isolated guinea-pig atrium.
Topics: Animals; Digitoxin; Digoxin; Female; Guinea Pigs; Heart Atria; Isomerism; Kinetics; Male; Myocardial Contraction; Myocardium; Ouabain | 1978 |
Accumulation of radioactive cardiac glycosides by various brain regions in relation to the dysrhythmogenic effect.
Topics: Animals; Brain; Digitoxin; Dogs; Female; Heart; Heart Rate; Male; Organ Specificity; Ouabain; Potassium | 1977 |
Digitalis glycosides--recent advances in clinical pharmacology and treatment.
Topics: Biological Availability; Cardiac Glycosides; Creatinine; Deslanoside; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Humans; Hypokalemia; Kidney Diseases; Liver Diseases; Malabsorption Syndromes; Obesity; Ouabain; Thyroid Diseases | 1977 |
Polynitro aromatic compounds in analytical chemistry I: reaction with ouabain and digitoxin.
Topics: Anisoles; Chemical Phenomena; Chemistry; Color; Digitoxin; Magnetic Resonance Spectroscopy; Nitro Compounds; Ouabain; Trinitrobenzenes | 1977 |
Binding of 16alpha-gitoxin and its 16-acetate to human serum albumin.
Topics: Chromatography, Gel; Dialysis; Digitalis Glycosides; Digitoxin; Humans; In Vitro Techniques; Ouabain; Protein Binding; Serum Albumin; Ultracentrifugation | 1977 |
Subcellular distribution of Deslanatoside C-3H in isolated guinea pig hearts. Interaction of other drugs.
Topics: Animals; Cell Nucleus; Creatine; Daunorubicin; Deslanoside; Digitoxin; Drug Interactions; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Lanatosides; Male; Microsomes; Mitochondria, Muscle; Myocardium; Ouabain; Perfusion; Phenobarbital; Time Factors | 1976 |
[Therapeutic equivalence and inequivalence of chemically identical substances using cardiac glycosides for an example (author's transpl)].
Topics: Animals; Binding Sites; Biological Availability; Cardiac Glycosides; Crystallization; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Half-Life; Humans; Intestinal Absorption; Kinetics; Lethal Dose 50; Ouabain; Rats; Receptors, Drug; Solubility; Surface Properties; Therapeutic Equivalency | 1976 |
[Concentration of cardiac glycosides in the heart and brain (author's transl)].
Topics: Animals; Brain; Cardiac Glycosides; Cats; Digitoxin; Digoxin; Myocardium; Ouabain; Plants, Medicinal | 1976 |
Differential species sensitivity to the inhibitory effect of cardiac glycosides on 3H-1-noradrenaline accumulation by tissue slices.
Topics: Animals; Cardiac Glycosides; Depression, Chemical; Digitoxin; Digoxin; Dogs; Guinea Pigs; Hydroxydopamines; In Vitro Techniques; Myocardium; Nerve Endings; Norepinephrine; Ouabain; Rats; Species Specificity; Spleen; Time Factors | 1976 |
Variant HeLa cells selected for their resistance to ouabain.
Topics: Alkaloids; Biological Transport, Active; Cardiac Glycosides; Cell Membrane; Culture Media; Cycloheximide; Digitoxigenin; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Drug Resistance; Female; Genetic Variation; HeLa Cells; Humans; Hypotonic Solutions; Osmosis; Ouabain; Sodium; Strophanthidin; Tritium | 1975 |
Hepatic uptake of cardiac glycosides in newborn rats, rabbits and dogs.
Topics: Age Factors; Animals; Animals, Newborn; Cardiac Glycosides; Digitoxin; Digoxin; Dogs; Liver; Myocardium; Ouabain; Rabbits; Rats; Time Factors | 1975 |
Studies on the kinetics of (3H)-ouabain uptake and exchange in the isolated papillary muscle of the guinea-pig.
Topics: Animals; Digitoxin; Electric Stimulation; Extracellular Space; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Myocardium; Ouabain; Papillary Muscles; Sucrose | 1975 |
Systems approach to study of solute transport across membranes using suspension cultures of mammalian cells V: Uptake and release kinetics of cardiac glycosides by Burkitt lymphoma cells.
Topics: Burkitt Lymphoma; Cell Membrane Permeability; Cells, Cultured; Digitoxin; Digoxin; Kinetics; Ouabain | 1975 |
Concentration of digoxin, methyldigoxin, digitoxin and ouabain in the myocardium of the dog following coronary occulsion.
Topics: Animals; Cardiac Glycosides; Chromatography, Thin Layer; Coronary Vessels; Digitoxin; Digoxin; Dogs; Electrocardiography; Ligation; Muscles; Myocardial Infarction; Myocardium; Ouabain; Time Factors; Tritium | 1975 |
The specific fluorimetric determination of digoxin.
Topics: Chemical Phenomena; Chemistry; Digitalis Glycosides; Digitoxin; Digoxin; Evaluation Studies as Topic; Microchemistry; Ouabain; Spectrometry, Fluorescence; Temperature; Time Factors | 1975 |
The effect of ouabain and digitoxin on hexobarbitone sleeping time in the mouse.
Topics: Animals; Digitoxin; Drug Synergism; Electrocardiography; Heart; Hexobarbital; Male; Microsomes, Liver; Ouabain; Proadifen; Sleep; Time Factors | 1975 |
Pharmacodynamic distinctions between ouabain, digoxin and digitoxin.
Topics: Animals; Digitoxin; Digoxin; Electrocardiography; Ethanol; Guinea Pigs; Heart Rate; Ouabain; Phonocardiography; Time Factors | 1975 |
Inotropic action, myocardial uptake and subcellular distribution of ouabain, digoxin and digitoxin in isolated rat hearts.
Topics: Animals; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Female; Half-Life; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Ouabain; Rats; Stimulation, Chemical; Time Factors | 1975 |
[Pharmacokinetics and action of digitoxin and ouabain in the isolated hearts of guinea pigs and rats].
Topics: Animals; Digitoxin; Guinea Pigs; Half-Life; In Vitro Techniques; Kinetics; Models, Biological; Myocardial Contraction; Myocardium; Ouabain; Perfusion; Rats; Stimulation, Chemical | 1975 |
Kinetics in interactions between antibodies and haptens.
Topics: Animals; Antibodies; Binding Sites; Digitoxin; Digoxin; Haptens; Kinetics; Mathematics; Ouabain; Rabbits; Sheep; Time Factors | 1975 |
[The polarographic determination of cardenolide nitrates].
Topics: Cardanolides; Chemical Phenomena; Chemistry; Cymarine; Digitoxigenin; Digitoxin; Digoxin; Nitrates; Ouabain; Oxidation-Reduction; Polarography; Strophanthidin | 1975 |
Studies on cardioactive steroids. III. Characterization of different cardiac glycosides by their effects on contractility and rhythmicity at different extracellular potassium concentrations.
Topics: Animals; Arrhythmias, Cardiac; Cardiac Glycosides; Cymarine; Digitoxin; Digoxin; Dimethylformamide; Female; Guinea Pigs; Heart Conduction System; Male; Myocardial Contraction; Ouabain; Potassium; Proscillaridin; Stimulation, Chemical | 1975 |
Effect of taurine on responses to noradrenaline, acetylcholine and ouabain in isolated auricles from digitalized guinea pigs.
Topics: Acetylcholine; Animals; Depression, Chemical; Digitoxin; Electrocardiography; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardium; Norepinephrine; Ouabain; Taurine; Time Factors | 1976 |
The positive inotropic drugs DPI 201-106, BDF 9148, and veratridine increase ouabain toxicity and [3H]ouabain binding in guinea pig heart.
Topics: Animals; Cardiotonic Agents; Digitoxin; Drug Synergism; Female; Guinea Pigs; Heart; Male; Myocardial Contraction; Myocardium; Ouabain; Piperazines; Veratridine | 1991 |
Effects of ouabain and digitoxin on the respiration of chick embryo cardiomyocytes in culture.
Topics: Animals; Cells, Cultured; Chick Embryo; Digitoxin; Models, Biological; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption; Perfusion | 1991 |
Liquid membrane phenomenon in the actions of digitalis.
Topics: Cholesterol; Digitoxin; Digoxin; Membranes; Micelles; Ouabain; Permeability; Phosphatidylcholines; Potassium; Sodium; Surface Properties | 1991 |
Concentrative uptake of digoxin by slices of chicken renal cortex.
Topics: Animals; Chickens; Digitoxin; Digoxigenin; Digoxin; Female; Hexoses; Kidney Cortex; Kinetics; Ouabain; Potassium; Probenecid; Quinine; Sodium Cyanide; Spironolactone | 1990 |
On the ocular distribution of cardiac glycosides in guinea pigs following acute administration.
Topics: Animals; Cardiac Glycosides; Digitoxin; Digoxin; Eye; Female; Guinea Pigs; Infusions, Intravenous; Male; Ouabain; Time Factors; Tissue Distribution; Tritium | 1989 |
In ability of Na+,K+-ATPase inhibitor to cause hypertension in sodium-loaded or deoxycorticosterone-treated one kidney rats.
Topics: Animals; Atropine; Blood Pressure; Desoxycorticosterone; Digitoxin; Enzyme Inhibitors; Hypertension; Kidney; Male; Ouabain; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors | 1985 |
(Na+,K+)-ATPase and noradrenergic regulation: effects of cardiac glycoside treatment and noradrenergic manipulations.
Topics: Animals; Benzylamines; Brain; Cardiac Glycosides; Clonidine; Desipramine; Digitoxin; Dihydroalprenolol; Kidney; Male; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase; Yohimbine | 1985 |
A system for deriving revertants of oncogene-transformed human cells.
Topics: Cell Line, Transformed; Cell Separation; Chromium; Digitoxin; Digoxin; Humans; Hydrogen-Ion Concentration; Mutation; Oncogenes; Ouabain; Phenotype; Potassium | 1988 |
Visualization of ouabain binding in bovine cornea.
Topics: Animals; Binding Sites; Cattle; Cornea; Digitoxin; Fluorescent Antibody Technique; Ouabain | 1987 |
Parallelism between transport inhibition and L1210 cell growth by ouabain.
Topics: Animals; Biological Transport; Cell Division; Cell Survival; Digitoxin; Digoxin; DNA Replication; Kinetics; Leukemia L1210; Ouabain; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Thymidine | 1988 |
[Acute electrophysiological effects of cardiac glycosides on sinus node function and ventricular repolarization under clinical conditions].
Topics: Cardiac Pacing, Artificial; Coronary Disease; Digitoxin; Digoxin; Electrocardiography; Electrophysiology; Female; Heart Conduction System; Humans; Male; Middle Aged; Myocardial Contraction; Ouabain; Sick Sinus Syndrome; Sinoatrial Node | 1987 |
Demonstration and characterization of two classes of cardiac glycoside binding sites to rat heart membrane preparations using quantitative computer modeling.
Topics: Animals; Binding, Competitive; Cardiac Glycosides; Cell Membrane; Digitoxin; Digoxin; Male; Myocardium; Ouabain; Potassium; Rats; Rats, Inbred Strains; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Software | 1987 |
Difference in degree of A-V block and QS2 abbreviation of ouabain digoxin and digitoxin in cats.
Topics: Animals; Atropine; Cats; Diet; Digitoxin; Digoxin; Electrocardiography; Female; Heart Block; Heart Rate; Male; Ouabain; Time Factors | 1986 |
Antiarrhythmic action of atropine.
Topics: Alkaloids; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Barium; Cardiac Complexes, Premature; Digitoxin; Dogs; Electrocardiography; Epinephrine; Guinea Pigs; Heart Atria; In Vitro Techniques; Ouabain; Petroleum; Tachycardia | 1971 |
Serum concentration and urinary excretion of 3 H-ouabain and 3 H-digitoxin in patients suffering from hyperthyroidism or hypothyroidism.
Topics: Adult; Aged; Antithyroid Agents; Digitoxin; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Ouabain; Thyroid Function Tests; Thyroid Hormones; Tritium | 1970 |
Mechanism of the inhibitory effects of cardiac glycosides on lipolysis.
Topics: Amides; Animals; Cardiac Glycosides; Cyclic AMP; Cysteine; Dicumarol; Digitoxin; Dinitrophenols; Ethylmaleimide; Glutathione; Glycerol; Hydrolysis; In Vitro Techniques; Iodoacetates; Lipid Metabolism; Lipid Mobilization; Male; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Theophylline | 1972 |
[The use of digitalis drugs in cardiac patients].
Topics: Atrial Flutter; Calcium; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; Digoxin; Heart Failure; Humans; Lanatosides; Long-Term Care; Ouabain; Quinidine; Tachycardia | 1969 |
[On the cause of species differences in digitalis sensitivity].
Topics: Adenosine Triphosphatases; Animals; Anura; Birds; Calcium; Cardiac Glycosides; Cats; Digitalis Glycosides; Digitoxin; Dogs; Guinea Pigs; In Vitro Techniques; Magnesium; Myocardium; Ouabain; Potassium; Prednisolone; Rats; Sodium; Species Specificity | 1965 |
Absence of effects of cardiac glycosides on cardiac myosin and A Ca++-sensitive reconstituted cardiac actomyosin.
Topics: Adenosine Triphosphatases; Animals; Calcium; Digitoxin; Dogs; Heart; In Vitro Techniques; Magnesium; Muscle Contraction; Muscle Proteins; Ouabain | 1966 |
Sarcoplasmic reticulum ATPase on a solid support.
Topics: Adenosine Triphosphatases; Animals; Azides; Biological Transport; Cellulose; Digitoxin; Membranes; Myocardium; Ouabain; Potassium; Rabbits; Sodium | 1966 |
[On differences in the mechanism of intestinal absorption of cardiotonic steroids and other drugs].
Topics: Animals; Cardanolides; Digitoxin; Heart; Hydrocortisone; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Lanatosides; Lysergic Acid Diethylamide; Ouabain; Perfusion; Plants, Medicinal; Quinine; Rats; Stimulation, Chemical | 1967 |
Studies on the interaction of ouabain and other cardio-active steroids with sodium-potassium-activated adenosine triphosphatase.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Cardanolides; Digitoxin; Digoxin; Eels; Electric Organ; Magnesium; Ouabain; Potassium; Sodium | 1968 |
The uptake and binding of six radiolabeled cardiac glycosides by guinea-pig hearts and by isolated sarcoplasmic reticulum.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Biological Transport; Cattle; Chromatography, Paper; Digitoxin; Digoxin; Guinea Pigs; Microsomes; Mononuclear Phagocyte System; Myocardium; Ouabain; Perfusion; Plants, Medicinal; Receptors, Drug; Tritium | 1968 |
[Determination of protein binding of different cardiac glycosides by means of Sephadex gel filtration].
Topics: Animals; Blood Proteins; Chromatography, Gel; Digitoxin; Digoxin; Guinea Pigs; Humans; Methods; Ouabain; Protein Binding; Tritium | 1968 |
[Intestinal absorption of cardiac glycosides in vitro and in vivo].
Topics: Animals; Binding Sites; Cardiac Glycosides; Digitoxin; Digoxin; Guinea Pigs; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Jejunum; Ouabain; Plants, Medicinal; Rats; Tritium | 1969 |
Effect of prostaglandin E1 on isolated short-circuited frog skin.
Topics: Adenosine Triphosphatases; Animals; Anura; Biological Transport, Active; Calcium; Digitoxin; Electric Conductivity; In Vitro Techniques; Ouabain; Permeability; Prostaglandins; Skin; Sodium | 1969 |
[On the characteristics of the binding of cardiac glycosides by plasma proteins].
Topics: Blood Proteins; Cardanolides; Chemical Phenomena; Chemistry; Chromatography, Gel; Digitoxin; Digoxin; Humans; Ouabain; Protein Binding; Serum Albumin; Ultracentrifugation | 1969 |
[Comparative study of intestinal resorption of 3H-labelled cardiac glycosides in vitro and in vivo].
Topics: Animals; Digitoxin; In Vitro Techniques; Intestinal Absorption; Jejunum; Ouabain; Plants, Medicinal; Rats; Tritium | 1968 |
[Binding of various cardiac glycosides to plasma proteins].
Topics: Animals; Blood Proteins; Chemical Phenomena; Chemistry; Digitoxin; Digoxin; Guinea Pigs; Humans; Ouabain; Protein Binding; Tritium | 1968 |
[Determination of the intestinal absorption of cardiac glycosides by measurement of 3H-labelled glycosides in the portal venous blood and in the intestinal lymph of cats].
Topics: Animals; Bile; Cardiac Glycosides; Cats; Digitoxin; Digoxin; Female; Intestinal Absorption; Intestine, Small; Jejunum; Lymph; Male; Ouabain; Portal Vein; Tritium | 1969 |
[Synergism of cardiac glycosides and potassium-containing electrolyte mixtures].
Topics: Aspartic Acid; Cardiac Glycosides; Digitoxin; Digoxin; Drug Synergism; Electrolytes; Isotonic Solutions; Magnesium; Ouabain; Plants, Medicinal; Potassium | 1969 |
Kinetic aspects of the inhibition of ATP-ase from red cell ghosts by cardiac glycosides.
Topics: Adenosine Triphosphatases; Animals; Digitoxin; Drug Stability; Erythrocytes; Female; Guinea Pigs; Kinetics; Male; Myocardium; Ouabain; Receptors, Drug | 1969 |
[Inhibition of potassium and sodium transport in erythrocytes by glycosides containing a saturated lactone ring].
Topics: Animals; Biological Transport, Active; Cardanolides; Cold Temperature; Depression, Chemical; Digitoxin; Erythrocytes; Guinea Pigs; In Vitro Techniques; Ouabain; Potassium; Sodium | 1970 |
Specific and non-specific uptake of cardiac glycosides.
Topics: Animals; Binding Sites; Cardiac Glycosides; Digitoxin; Digoxin; Guinea Pigs; In Vitro Techniques; Intestine, Small; Muscle, Smooth; Ouabain; Tritium | 1970 |
[Direct determination of intestinal absorption of tritium-labelled cardiac glycosides by measurement of portal and arterial concentrations and volume of portal vein flow in guinea pigs].
Topics: Animals; Cardiac Glycosides; Carotid Arteries; Digitoxin; Digoxin; Guinea Pigs; Intestinal Absorption; Ouabain; Portal Vein; Tritium | 1970 |
[Toxicity and combination toxicity of cardiac glycosides at an optimal molar titer and long survival time].
Topics: Animals; Cardanolides; Cardiac Glycosides; Digitalis Glycosides; Digitoxin; Drug Synergism; Guinea Pigs; Ouabain; Time Factors | 1970 |
[Metabolic degradation of 3H-labelled cardiac glycosides by the isolated perfused guinea pig liver].
Topics: Animals; Blood Proteins; Cardiac Glycosides; Digitoxin; Digoxin; Guinea Pigs; In Vitro Techniques; Liver; Ouabain; Perfusion; Protein Binding; Tritium | 1970 |
[Plasma elimination, hepatic uptake and biliary excretion of tritiated cardiac glycosides by the isolated perfused liver].
Topics: Animals; Bile; Digitoxin; Digoxin; Guinea Pigs; In Vitro Techniques; Liver; Ouabain; Perfusion; Tritium | 1970 |
[Binding of cardiac glycosides with sarcoplasmic reticulum and cell membrane isolatd from the heart muscle of the cat].
Topics: Acetone; Adenosine Triphosphatases; Animals; Calcium; Cats; Cell Membrane; Cholesterol; Digitoxin; Endoplasmic Reticulum; Female; In Vitro Techniques; Male; Myocardium; Ouabain; Phospholipases; Phospholipids; Pituitary Hormone-Releasing Hormones; Proteins; Tritium | 1971 |
[Biochemical aspects of digitalis therapy].
Topics: Adenosine Triphosphatases; Animals; Anura; Biotransformation; Brain; Calcium; Cardanolides; Cats; Chemistry Techniques, Analytical; Depression, Chemical; Digitalis Glycosides; Digitoxin; Dogs; Drug Synergism; Heart; Heart Diseases; Heart Failure; Humans; Liver; Myocardium; Ouabain; Potassium; Rabbits; Rats; Stimulation, Chemical; Time Factors | 1971 |
Distribution of digoxin, digitoxin and ouabain between plasma and erythrocytes in various species.
Topics: Animals; Blood Proteins; Buffers; Cardiac Glycosides; Cats; Cattle; Cell Membrane; Digitoxin; Digoxin; Dogs; Erythrocytes; Guinea Pigs; Hemoglobins; Humans; Ouabain; Plasma; Protein Binding; Rats; Species Specificity | 1971 |
[Influence of cardiac glycosides on the uptake of 5-HT by blood platelets].
Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Blood Platelets; Cardiac Glycosides; Depression, Chemical; Digitoxin; Digoxin; In Vitro Techniques; Norepinephrine; Ouabain; Potassium; Rabbits; Serotonin | 1971 |
Binding of cardiac glycosides to isolated jejunal brush borders from rat and guinea pig and their influence on membrane phosphatase systems.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Bufanolides; Cardiac Glycosides; Cell Membrane; Chlorides; Digitoxin; Digoxin; Enzyme Activation; Female; Guinea Pigs; Intestinal Mucosa; Jejunum; Magnesium; Nitrobenzenes; Ouabain; Plants, Medicinal; Potassium Chloride; Pyrans; Rats; Receptors, Drug; Sodium Chloride; Species Specificity; Tritium | 1971 |
The ouabain inhibition of sugar transport in kidney cortex cells.
Topics: Adenosine Triphosphatases; Aerobiosis; Anaerobiosis; Animals; Binding Sites; Biological Transport, Active; Calcium; Carbon Isotopes; Cell Membrane; Digitoxin; Dinitrophenols; Glycosides; Hot Temperature; Kidney; Kinetics; Lithium; Magnesium; Ouabain; Potassium; Rabbits; Rats; Sodium; Species Specificity; Temperature; Tritium; Water | 1971 |
Uptake of cardiac glycosides by rabbit and rat myometrium.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport, Active; Cardiac Glycosides; Cesium; Digitoxin; Female; In Vitro Techniques; Kinetics; Muscle, Smooth; Ouabain; Potassium; Rabbits; Rats; Rats, Inbred Strains; Sodium; Temperature; Tritium; Uterus | 1972 |
The effect of protein binding on the uptake of ouabain and digitoxin into the perfused heart preparation.
Topics: Animals; Digitoxin; Female; Guinea Pigs; Heart; Male; Models, Biological; Myocardium; Ouabain; Perfusion; Protein Binding; Receptors, Drug; Serum Albumin, Bovine; Tritium | 1972 |
[The effect of probenecid on the distribution of digitoxin, digoxin and ouabain in the mouse].
Topics: Animals; Chromatography, Thin Layer; Digitoxin; Digoxin; Heart; Liver; Mice; Muscles; Myocardium; Ouabain; Probenecid; Tritium | 1973 |
The inhibition of the Na-K-ATPase of guinea-pig heart microsomes by cardiac glycosides.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Cardiac Glycosides; Digitoxin; Guinea Pigs; Heart; Microsomes; Myocardium; Ouabain; Potassium; Receptors, Drug; Sodium | 1973 |
Characterization and specificity of proscillaridin antibodies.
Topics: Animals; Antibodies; Antibody Specificity; Bufanolides; Cardanolides; Cholesterol; Digitalis Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Electrophoresis; Erythrocytes; Humans; Immunodiffusion; Immunoelectrophoresis; Ouabain; Plants, Medicinal; Precipitins; Rabbits; Radioimmunoassay; Radioisotopes; Rubidium; Serum Albumin; Testosterone; Tritium | 1973 |
Alterations produced by novobiocin during biliary excretion of morphine, morphine-3-glucuronide and other compounds.
Topics: Analysis of Variance; Animals; Bile; Bilirubin; Carbon Radioisotopes; Digitoxin; Glucuronates; Liver; Male; Mannitol; Morphine; Niacinamide; Novobiocin; Ouabain; Procainamide; Rats; Sulfobromophthalein; Time Factors; Tritium; Tubocurarine | 1974 |
Dissociation of contractile effect and binding and inhibition of Na+-K+-adenosine triphosphatase by cardiac glycosides in rabbit myometrium.
Topics: Acetylcholine; Adenosine Triphosphatases; Animals; Cardiac Glycosides; Cell Membrane; Digitoxin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Rabbits; Sodium; Time Factors; Tritium; Uterus | 1974 |
The effect of various cardenolides and bufadienolides with different cardiac activity on the 86-rubidium uptake of human erythrocytes.
Topics: Animals; Biological Transport, Active; Bufanolides; Cardanolides; Cardiac Glycosides; Cats; Digitalis Glycosides; Digitoxin; Digoxin; Erythrocytes; Guinea Pigs; Humans; In Vitro Techniques; Lethal Dose 50; Male; Ouabain; Plants, Medicinal; Radioisotopes; Rubidium; Structure-Activity Relationship | 1973 |
On the relations between serotonin uptake and function of the transport-ATPase system of blood platelets.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport; Blood Platelets; Digitoxin; Ouabain; Potassium; Rabbits; Serotonin; Serotonin Antagonists | 1973 |
Studies on cardioactive steroids. II. Structure-activity relationships in the isolated guinea-pig heart.
Topics: Acetylation; Adenosine Triphosphatases; Animals; Bufanolides; Cardiac Glycosides; Digitoxin; Digoxin; Drug Evaluation, Preclinical; Esters; Female; Guinea Pigs; Heart; Heart Rate; Hydroxylation; Male; Nitro Compounds; Ouabain; Stimulation, Chemical; Strophanthins; Structure-Activity Relationship; Time Factors | 1974 |
Proceedings: On antifibrillatory properties of cardiac glycosides.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Glycosides; Digitoxin; Digoxin; Electric Stimulation; Electrocardiography; Female; Guinea Pigs; Ouabain; Time Factors; Ventricular Fibrillation | 1974 |
Proceedings: Different dependence of the toxic action of some cardiotonic steroids on the serum potassium level in guinea pigs.
Topics: Animals; Cardanolides; Cardiac Glycosides; Digitoxin; Guinea Pigs; Lethal Dose 50; Ouabain; Potassium | 1974 |
Isolation of a digitoxin-bound protein from a brain membrane preparation containing Na+, K+-activated ATPase.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Brain; Brain Chemistry; Cattle; Chromatography, Gel; Digitoxin; Electrophoresis, Polyacrylamide Gel; Microsomes; Nerve Tissue Proteins; Ouabain; Phosphorus Radioisotopes; Potassium; Protein Binding; Receptors, Drug; Sodium; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Na, K-activated ATPase activity during and after arrhythmic response to AY-22-241 in the canine heart.
Topics: Adenosine Triphosphatases; Animals; Arrhythmias, Cardiac; Cardanolides; Cardiac Glycosides; Digitoxin; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Heart; Myocardium; Ouabain; Potassium; Sodium; Species Specificity; Stimulation, Chemical; Structure-Activity Relationship; Subcellular Fractions; Swine; Time Factors | 1974 |
Cardiac glucosides: correlations among Na+ K+-ATPase, sodium pump and contractility in the guinea pig heart.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport, Active; Cardiac Glycosides; Digitoxin; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Ouabain; Perfusion; Potassium; Radioisotopes; Rubidium; Sodium; Time Factors; Tritium | 1974 |
The effects of cardiac glycosides and their interaction with catecholamines on glycolysis and glycogenolysis in skeletal muscle.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Cyclic AMP; Diaphragm; Digitoxin; Epinephrine; Gluconeogenesis; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; Hexosephosphates; Lactates; Male; Muscles; Norepinephrine; Ouabain; Oxygen Consumption; Pyruvates; Rats | 1968 |
Mechanism of antilipolytic effects of cardiac glycosides.
Topics: Adipose Tissue; Animals; Butyrates; Cardiac Glycosides; Cell Membrane; Cyclic AMP; Digitoxin; Epididymis; Esters; Glycerol; In Vitro Techniques; Lipid Metabolism; Male; Norepinephrine; Ouabain; Phosphoric Monoester Hydrolases; Potassium; Rats; Strophanthins; Theophylline; Tritium | 1971 |
Subcellular distribution of cardiac glycosides in rabbit and rat myometrium and their binding to isolated plasma membrane.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiac Glycosides; Cell Membrane; Centrifugation, Density Gradient; Cytochrome c Group; Digitoxin; Electron Transport Complex IV; Female; Microscopy, Electron; Muscle, Smooth; Nucleotidases; Ouabain; Phosphoric Monoester Hydrolases; Pregnancy; Proteins; Rabbits; Rats; Species Specificity; Sucrose; Tritium; Uterus | 1974 |
Effect of reserpine and pronethalol on the therapeutic and toxic actions of digitalis in the dog heart-lung preparation.
Topics: Animals; Digitoxin; Dogs; Ethanolamines; Heart; Heart Conduction System; Heart Rate; Heart Ventricles; In Vitro Techniques; Ouabain; Reserpine; Ventricular Fibrillation | 1967 |
Post-countershock arrhythmias in untreated and digitalized dogs.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Catecholamines; Cocaine; Denervation; Digitoxin; Dogs; Electric Countershock; Ethanolamines; Heart; Isoproterenol; Ouabain; Propranolol; Reserpine | 1967 |
The influence of cardiac glycosides on membrane permeability in guinea-pig atrial tissue, determined by means of 86Rb.
Topics: Animals; Cardiac Glycosides; Cell Membrane Permeability; Digitoxin; Digoxin; Guinea Pigs; Heart Atria; Methods; Ouabain; Radioisotopes; Rubidium | 1968 |
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.
Topics: Analysis of Variance; Animals; Bile; Biotransformation; Cardiac Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Enzyme Induction; Lethal Dose 50; Liver; Male; Methylcholanthrene; Microsomes; Myocardium; Organ Size; Ouabain; Paralysis; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors; Tritium; Zoxazolamine | 1974 |
The effect of probenecid on the in vitro absorption of cardiac glycosides.
Topics: Animals; Biological Transport; Body Water; Calcium; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Ethacrynic Acid; Furosemide; Glucose; Hydrochlorothiazide; In Vitro Techniques; Intestinal Absorption; Jejunum; Mersalyl; Mice; Mice, Inbred Strains; Osmolar Concentration; Ouabain; Oxygen Consumption; Potassium; Probenecid; Sodium; Tritium | 1974 |
Neurological, respiratory and cardiac effects of cardiac glycoside administered intracerebrally to conscious mice.
Topics: Animals; Behavior, Animal; Cardiac Glycosides; Cerebral Ventricles; Depression, Chemical; Digitoxin; Digoxin; Electrocardiography; Heart; Heart Rate; Injections; Injections, Intravenous; Lethal Dose 50; Mice; Ouabain; Respiration; Seizures | 1974 |
[Subcellular distribution of desacetyl-lanatoside C, ouabain and digitoxin in the liver of awake guinea pigs].
Topics: Animals; Deslanoside; Digitoxin; Guinea Pigs; Injections, Intravenous; Lanatosides; Liver; Ouabain | 1974 |
Probenecid and hepatic transport of 3-H-ouabain in rats.
Topics: Alkadienes; Animals; Benzoxazoles; Coloring Agents; Cresols; Depression, Chemical; Digitoxin; In Vitro Techniques; Kinetics; Liver; Male; Ouabain; Probenecid; Rats; Temperature | 1974 |
Interpretation of post mortem serum levels of cardiac glycosides after suspected overdosage.
Topics: Administration, Oral; Aged; Antibodies; Autopsy; Cardiac Glycosides; Cross Reactions; Digitoxin; Digoxin; Female; Humans; Infant; Injections, Intramuscular; Iodine Radioisotopes; Lanatosides; Male; Middle Aged; Ouabain; Radioimmunoassay; Suicide | 1974 |
Inhibition of sodium transport in frog skin by cardiac glycosides of different molecular structure.
Topics: Animals; Anura; Biological Transport, Active; Cardiac Glycosides; Digitoxin; Lanatosides; Ouabain; Rana temporaria; Skin; Sodium; Strophanthins; Structure-Activity Relationship | 1972 |
Absorption rates of some cardiac glycosides and portal blood flow.
Topics: Animals; Bile; Blood Flow Velocity; Cardiac Glycosides; Digitoxin; Digoxin; Guinea Pigs; Intestinal Absorption; Intestines; Kinetics; Ouabain; Portal System; Tritium | 1972 |
Effects of some cardiac glycosides on the post-hypoxic enzyme release from isolated rat hearts.
Topics: Animals; Cardiac Glycosides; Digitalis Glycosides; Digitoxin; Heart; Hypoxia; In Vitro Techniques; L-Lactate Dehydrogenase; Myocardium; Ouabain; Rats; Spectrophotometry; Temperature | 1972 |
The uptake of cardiac glycosides in relation to their actions in isolated cardiac muscle.
Topics: Animals; Binding Sites; Biological Transport, Active; Cardiac Glycosides; Digitoxin; Guinea Pigs; Heart Atria; In Vitro Techniques; Myocardium; Ouabain; Potassium; Sodium; Tritium | 1972 |
Liver cell potentials: in vitro effects of metabolic inhibitors, cardiac glycosides, and hormones.
Topics: Acetamides; Animals; Cell Membrane; Cyanides; Digitoxin; Dinitrophenols; Epinephrine; Female; In Vitro Techniques; Insulin; Iodoacetates; Kinetics; Liver; Male; Membrane Potentials; Ouabain; Rats; Thyroxine; Time Factors | 1972 |
[Studies on the active or passive enteral resorption of cardiac glycosides].
Topics: Animals; Cardiac Glycosides; Digitoxin; Digoxin; Female; Intestinal Absorption; Jejunum; Male; Ouabain; Oxygen Consumption; Plants, Medicinal; Rats | 1972 |
[Digitoxin and g-strophanthin absorption in the perfused small intestine loop of the rat].
Topics: Animals; Bufanolides; Digitoxin; Dose-Response Relationship, Drug; Intestinal Absorption; Intestine, Small; Ouabain; Perfusion; Rats; Tritium | 1972 |
Response of P-Q intervals to digitalis glycosides in the dog.
Topics: Animals; Digitoxin; Dogs; Electrocardiography; Female; Heart Rate; Ouabain | 1973 |
Biliary excretion of cardiac glycosides.
Topics: Animals; Bile; Cardiac Glycosides; Digitoxin; Digoxin; Dogs; Lethal Dose 50; Liver; Male; Myocardium; Ouabain; Rabbits; Rats; Species Specificity; Time Factors; Tritium | 1973 |
[New aspects in the mechanism of action of cardiac glycosides].
Topics: Biotransformation; Cardiac Glycosides; Digitoxin; Digoxin; Heart; Humans; Lanatosides; Ouabain; Plants, Medicinal; Strophanthins | 1973 |
[Drug interactions between cardiac glycosides and beta-sympathomimetics].
Topics: Amino Alcohols; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Glycosides; Cardiac Output; Cats; Digitoxin; Digoxin; Drug Interactions; Drug Synergism; Female; Guinea Pigs; Heart; Heart Rate; Isoproterenol; Male; Ouabain; Phenethylamines; Propiophenones; Reserpine; Sympathomimetics | 1973 |
Absorption of cardiac glycosides from the rat respiratory tract.
Topics: Adsorption; Animals; Cardiac Glycosides; Chemical Phenomena; Chemistry, Physical; Chromatography, Thin Layer; Digitoxin; Digoxin; Kinetics; Lung; Male; Ouabain; Rats; Respiratory System; Time Factors; Tritium | 1973 |
[Plasmatic levels and urinary elimination of K-strophanthoside after intravenous administration in normal humans].
Topics: Digitoxin; Digoxin; Humans; Injections, Intravenous; Ouabain; Strophanthins | 1973 |
[Effect of cardioactive steroids on active intestinal sugar transport in hamster (author's transl)].
Topics: Animals; Biological Transport, Active; Cardanolides; Cardiac Glycosides; Cricetinae; Digitoxin; Galactose; Ileum; Intestine, Small; Jejunum; Lanatosides; Ouabain; Plants, Medicinal | 1973 |
Normal systolic time intervals in awake dogs and their response to digitalis glycosides.
Topics: Animals; Blood Pressure; Cardiac Output; Carotid Arteries; Computers; Digitalis Glycosides; Digitoxin; Dogs; Electrocardiography; Heart Rate; Heart Ventricles; Ouabain; Phonocardiography; Pulse; Respiration; Time Factors; Ventricular Function; Wakefulness | 1974 |
Uraemic and normal plasma protein binding of various cardiac glycosides under "in vivo" conditions.
Topics: Blood Proteins; Cardiac Glycosides; Digitoxin; Digoxin; Humans; Membranes, Artificial; Ouabain; Protein Binding; Renal Dialysis; Strophanthins; Tritium; Uremia | 1974 |
[Letter: Heart therapy in cerebrovascular complications].
Topics: Cerebrovascular Disorders; Digitoxin; Heart Diseases; Humans; Ouabain; Strophanthins | 1974 |
Divergent influences of Ca2+ on the action of several cardiotonic steroids in isolated heart muscle preparations.
Topics: Animals; Calcium; Cardanolides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Ouabain; Papillary Muscles; Steroids; Time Factors | 1974 |
[Estimation of minimal lethal doses by infusion-toxicity and determination of the duration of action of cardiac glycosides].
Topics: Adenosine; Animals; Bradycardia; Bufanolides; Cardiac Glycosides; Cardiac Output; Digitalis Glycosides; Digitoxin; Digoxin; Guinea Pigs; Heart Arrest; Heart Block; Infusions, Parenteral; Lethal Dose 50; Mathematics; Ouabain; Plants, Medicinal; Time Factors | 1974 |
[Biochemistry and clinical aspects of digitalis].
Topics: Animals; Biochemical Phenomena; Biochemistry; Cardanolides; Cats; Digestive System; Digitalis Glycosides; Digitoxin; Dogs; Guinea Pigs; Heart; Humans; Myocardium; Ouabain; Rabbits | 1966 |
Effect of metabolic inhibitors on the accumulation of digitaloids by the isolated guinea-pig heart.
Topics: Animals; Digitalis Glycosides; Digitoxin; Female; Glucose; Guinea Pigs; Heart; In Vitro Techniques; Insulin; Iodoacetates; Male; Myocardium; Ouabain; Oxygen Consumption; Perfusion; Phloretin; Phlorhizin; Potassium; Pyruvates; Time Factors; Tritium | 1972 |
Studies on cellular adhesion in tissue culture. XI. Some effects of ouabain.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Adhesion; Chromium Isotopes; Digitalis Glycosides; Digitoxin; Electrophoresis; Glass; In Vitro Techniques; Membrane Potentials; Ouabain; Potassium; Sodium; Stimulation, Chemical; Tyrothricin; Valinomycin | 1972 |
Ion transport of ouabain resistant and sensitive Ehrlich ascites carcinoma cells.
Topics: Amino Acids; Animals; Autoradiography; Biological Transport, Active; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Digitoxin; Digoxin; Drug Resistance; Glucosamine; Mice; Mitosis; Neuraminidase; Ouabain; Potassium; Potassium Isotopes; Ribonucleases; Sodium; Thymidine; Time Factors; Tritium; Uridine | 1972 |
[Subcellular distribution of tritium-labeled cardiac glycosides in isolated cat and guinea-pig heart muscles].
Topics: Animals; Cats; Cell Fractionation; Digitoxin; Female; Guinea Pigs; In Vitro Techniques; Male; Microsomes; Mitochondria; Myocardium; Ouabain; Perfusion; Proteins; Tritium | 1971 |
[Animal experiment studies on the change of glycoside sensitivity due to blood-pH shifting].
Topics: Acidosis, Respiratory; Animals; Blood; Cats; Digitoxin; Digoxin; Hydrogen-Ion Concentration; Lethal Dose 50; Ouabain | 1971 |
[Metabolism of cardioactive glycosides].
Topics: Aged; Cardanolides; Cardiac Glycosides; Chemistry, Pharmaceutical; Digitalis Glycosides; Digitoxin; Digoxin; Humans; Lanatosides; Middle Aged; Ouabain; Plants, Medicinal; Strophanthins | 1971 |
[Relationship between toxicity and concentration of cardiac glycosides in the myocardium of various animals].
Topics: Animals; Cats; Digitoxin; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Ouabain; Perfusion; Rats; Species Specificity; Tritium | 1971 |
Aphagia, produced by deposition of drugs into the hypothalamus of rats.
Topics: Acetates; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Biological Transport, Active; Chlormerodrin; Digitoxin; Drinking Behavior; Eating; Ethacrynic Acid; Feeding and Eating Disorders; Feeding Behavior; Furosemide; Humans; Hypothalamus; Inhibition, Psychological; Injections, Intraperitoneal; Mercury; Ouabain; Sodium; Sodium Chloride; Stimulation, Chemical | 1970 |
Availability of cardiac glycosides for pharmacological receptor-site of muscle cells and positive inotropic action.
Topics: Animals; Anura; Crustacea; Digitoxin; Extracellular Space; Heart; Muscles; Ouabain; Receptors, Drug; Tritium | 1969 |
Factors that regulate ouabain-H3 accumulation by the isolated guinea-pig heart.
Topics: Animals; Calcium; Digitoxin; Female; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Microsomes; Mitochondria; Myocardium; Ouabain; Perfusion; Potassium; Sodium; Time Factors; Tritium | 1969 |
Effect of spironolactone and norbolethone on the toxicity of digitalis compounds in the rat.
Topics: Anabolic Agents; Animals; Cardanolides; Cardiac Glycosides; Digitalis Glycosides; Digitoxin; Digoxin; Female; Ouabain; Rats; Spironolactone; Strophanthins | 1969 |
Studies on the elimination of digitoxin and ouabain in the dog, using the tolerance test of repeated intravenous infusions.
Topics: Animals; Biotransformation; Cardanolides; Digitoxin; Dogs; Electrocardiography; Heart Conduction System; Heart Rate; Injections, Intravenous; Ouabain; Potassium; Time Factors | 1969 |
[Serum half-life and renal clearance of 3H peruvoside. Study on normal persons and patients with terminal kidney insufficiency].
Topics: Cardanolides; Cardiac Glycosides; Digitoxin; Digoxin; Humans; Kidney; Kidney Failure, Chronic; Ouabain; Pyrans; Strophanthins; Time Factors; Tritium | 1969 |
[Demonstration of the specific connection of cardiotonic glycosides to an isolated muscle preparation].
Topics: Animals; Biological Transport, Active; Digitoxin; Digoxin; Guinea Pigs; Ileum; Muscles; Ouabain; Tritium | 1969 |
Intestinal absorption of 3H-ouabain: demonstration of a nonsaturable transport process.
Topics: Animals; Azides; Biological Transport; Biological Transport, Active; Digitoxin; Digoxin; Dinitrophenols; Female; Gastric Mucosa; Glucose; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Iodoacetates; Kinetics; Ouabain; Oxygen; Rats; Sodium; Time Factors; Tritium | 1970 |
Cardiac glycoside effects on rat skeletal muscle potentials and electrolytes.
Topics: Action Potentials; Animals; Blood Chemical Analysis; Calcium; Chlorides; Digitoxin; Injections, Subcutaneous; Magnesium; Male; Membrane Potentials; Muscles; Ouabain; Potassium; Rats; Sodium; Water | 1970 |
[Comulative behavior of various cardiac glycosides in anuria].
Topics: Adolescent; Adult; Anuria; Cardiac Glycosides; Chromatography, Paper; Digitoxin; Digoxin; Female; Humans; Injections, Intravenous; Male; Middle Aged; Ouabain; Renal Dialysis; Tritium | 1970 |
Some cyclic ketals and acetals of digitoxin, digoxin, and ouabain.
Topics: Animals; Cats; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Digitoxin; Digoxin; Ouabain; Spectrophotometry; Ultraviolet Rays | 1970 |
The effects of six cardiac glycosides on the transmembrane potential and contractile characteristics of the right ventricle of guinea pigs.
Topics: Action Potentials; Animals; Anura; Cardiac Glycosides; Cats; Chick Embryo; Digitoxin; Digoxin; Dogs; Guinea Pigs; Heart Ventricles; Male; Membrane Potentials; Muscle Contraction; Ouabain; Papillary Muscles; Sheep; Strophanthins; Time Factors | 1970 |
The uptake of cardiac glycosides by intestinal smooth muscle of the guinea-pig in relation to digitalis receptors.
Topics: Animals; Binding Sites; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Muscle, Smooth; Ouabain; Receptors, Drug; Tritium | 1970 |
Antiarrhythmic effects of proadifen hydrochloride (SKF 525-A).
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Barbiturates; Barium; Blood Pressure; Bradycardia; Chlorides; Conjunctiva; Cornea; Depression, Chemical; Digitoxin; Dogs; Electrocardiography; Epinephrine; Heart Rate; Hydrochloric Acid; Hypotension; Imipramine; Irritants; Ouabain; Petroleum; Proadifen; Rabbits; Reflex | 1970 |
Seizure activity evoked by implantation of ouabain and related drugs into cortical and subcortical regions of the rabbit brain.
Topics: Acetates; Animals; Brain; Caudate Nucleus; Digitoxin; Electroencephalography; Ethacrynic Acid; Female; Geniculate Bodies; Hippocampus; Hypothalamus; Male; Mercury; Ouabain; Rabbits; Reticular Formation; Seizures; Thalamus | 1970 |
[The binding capacity of serum proteins for cardanolides and the influence of calcium].
Topics: Animals; Biopharmaceutics; Blood Protein Electrophoresis; Blood Proteins; Calcium; Cardanolides; Cats; Digitoxin; Digoxin; Humans; Ions; Ouabain; Protein Binding; Solubility; Solutions; Temperature | 1970 |
Effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) in experimental chloroform-epinephrine and digitalis dysrhythmias.
Topics: Animals; Blood Pressure; Bufanolides; Cats; Chloroform; Digitalis Glycosides; Digitoxin; Electrocardiography; Epinephrine; Female; Heart; Heart Rate; Isoproterenol; Male; Norepinephrine; Ouabain; Phenoxybenzamine; Plants, Medicinal; Quinolines | 1970 |
[Determination of cardiotoxicity of cardiac glycosides in the cat. II. Method of intravenous and intraduodenal infusion assay, planning, execution and evaluation of screening tests].
Topics: Animals; Cardiac Glycosides; Cats; Digitoxin; Digoxin; Duodenum; Electrocardiography; Female; Heart; Infusions, Parenteral; Injections, Intravenous; Male; Mathematics; Models, Biological; Ouabain; Statistics as Topic; Time Factors | 1970 |
Metabolism of cardiac glycosides--II. Cardiotoxicity of metabolites of digitoxin-7 aalpha-T.
Topics: Animals; Biological Assay; Cardanolides; Cats; Chromatography, Paper; Chromatography, Thin Layer; Countercurrent Distribution; Digitoxin; Electrocardiography; Female; Heart; Male; Ouabain; Potassium Chloride; Rabbits; Species Specificity; Tritium | 1971 |
Plasma concentration, uptake by liver, and biliary excretion of tritiated cardiac glycosides in the isolated perfused guinea-pig liver.
Topics: Animals; Bile; Biliary Tract; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Female; Guinea Pigs; In Vitro Techniques; Liver; Male; Models, Biological; Ouabain; Perfusion; Tritium | 1971 |
Metabolism of cardiac glycosides studied in the isolated perfused guinea-pig liver.
Topics: Animals; Blood Proteins; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Guinea Pigs; Hydrolysis; In Vitro Techniques; Liver; Ouabain; Perfusion; Protein Binding; Ultracentrifugation | 1971 |
Cat assay for the emetic action of digitalis and related glycosides (digitoxin, digoxin, lanatoside C, ouabain and calactin).
Topics: Animals; Cats; Central Nervous System; Computers, Analog; Digitalis Glycosides; Digitoxin; Digoxin; Emetics; Heart; Lanatosides; Models, Biological; Ouabain; Receptors, Drug | 1971 |
[Effect of cardiac glycosides on calcium, sodium, water and glucose transport in the isolated small intestine].
Topics: Animals; Biological Transport, Active; Calcium; Depression, Chemical; Digitoxin; Female; Glucose; Guinea Pigs; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Jejunum; Ouabain; Plants, Medicinal; Sodium; Water | 1967 |
[Evaluation of inotropically active drugs on isolated papillary muscle].
Topics: Animals; Cardiac Glycosides; Digitoxin; Digoxin; Guinea Pigs; Heart; In Vitro Techniques; Muscle Contraction; Ouabain; Papillary Muscles; Protein Binding; Time Factors | 1967 |
[Effect of cardiac glycosides on the automaticity of isolated heart cells in vitro].
Topics: Animals; Biological Assay; Cardiac Glycosides; Chick Embryo; Culture Techniques; Digitoxin; Heart; Heart Ventricles; Methods; Ouabain; Strophanthins | 1967 |
A comparison of the accumulation and release of 3H-ouabain and 3H-digitoxin by guinea-pig heart muscle.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Digitoxin; Electric Stimulation; Guinea Pigs; Heart; Muscle Contraction; Myocardium; Ouabain; Receptors, Drug; Time Factors; Transducers; Tritium | 1968 |
Biliary secretion of ouabain-3H and its uptake by liver slices in the rat.
Topics: Aminohippuric Acids; Animals; Bile; Biological Transport, Active; Chromatography, Thin Layer; Digitoxin; Digoxin; Glycosides; Injections, Intravenous; Liver; Liver Extracts; Male; Organ Size; Ouabain; Parasympatholytics; Plants, Medicinal; Probenecid; Procainamide; Rats; Tritium | 1968 |
[On the effect of phenytoin on digitalis-precipitated arrhythmias].
Topics: Animals; Arrhythmias, Cardiac; Digitoxin; Electrocardiography; Guinea Pigs; Heart Atria; Ouabain; Phenytoin | 1968 |
The uptake of 3H-ouabain and 3H-digitoxin by guinea pig atria, previously extracted with glycerol.
Topics: Animals; Digitoxin; Glycerol; Guinea Pigs; Heart Atria; In Vitro Techniques; Methods; Ouabain; Protein Binding; Tritium | 1968 |
[On the blood level and secretion of radioactively labeled cardiac glycosides following intraduodenal application in the cat].
Topics: Animals; Bile; Cardiac Glycosides; Cats; Digitoxin; Digoxin; Ouabain; Strophanthins; Tritium | 1968 |
Effects of dimethyl sulfoxide (DMSO) on cardiovascular responses to ouabain, proscillaridin and digitoxin.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Cats; Digitoxin; Dimethyl Sulfoxide; Drug Synergism; Electrocardiography; Female; Glycosides; Heart Rate; Infusions, Parenteral; Male; Ouabain; Plants, Medicinal; Ventricular Fibrillation | 1968 |
The binding of 3H-peruvoside by guinea pig isolated atria.
Topics: Animals; Cardiac Glycosides; Chromatography, Thin Layer; Culture Media; Digitoxin; Digoxin; Guinea Pigs; Heart Atria; In Vitro Techniques; Myocardium; Ouabain; Tritium | 1968 |
[On the effect of a calcium chloride infusion on the toxicity of some cardiac glycosides].
Topics: Animals; Calcium; Calcium Chloride; Cardiac Glycosides; Digitoxin; Digoxin; Drug Synergism; Guinea Pigs; Male; Ouabain; Potassium; Sodium; Strophanthins | 1968 |
[On the pharmacokinetics of peruvoside. II. Comparative studies with H3-ouabain and H3-digitoxin in guinea pigs].
Topics: Animals; Bile; Cardiac Glycosides; Digitoxin; Feces; Guinea Pigs; Intestines; Kinetics; Ouabain; Protein Binding; Tritium | 1968 |
The distribution of 3H-labelled cardenolides between isolated guinea-pig atrial tissue and circulating, oxygenated whole blood.
Topics: Animals; Cardanolides; Digitoxin; Digoxin; Erythrocytes; Guinea Pigs; Heart Atria; In Vitro Techniques; Methods; Myocardium; Ouabain; Perfusion; Protein Binding; Tritium | 1969 |
The correlation between the decline of the positive inotropic effect and the loss of cardiac glycosides from isolated atria during wash-out.
Topics: Animals; Cardiac Glycosides; Digitoxin; Digoxin; Electric Stimulation; Extracellular Space; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Myocardium; Ouabain; Tritium | 1969 |
[Comparative study of absorption and elimination of tritium-labelled cardiac glycosides].
Topics: Animals; Bile; Cardiac Glycosides; Digitoxin; Intestinal Absorption; Jejunum; Lymph; Ouabain; Portal Vein; Rats; Tritium | 1969 |
[Changes in cardiac glycosides induced by 60Co gamma radiations].
Topics: Cardiac Glycosides; Digitoxin; Ouabain; Radiation Effects; Spectrometry, Gamma; Strophanthins | 1969 |
[Studies in guinea pigs and rats on the action of cardiac glycosides on the electrocardiogram, heart rate and blood pressure].
Topics: Animals; Blood Pressure; Digitoxin; Digoxin; Electrocardiography; Guinea Pigs; Heart Rate; Lanatosides; Ouabain; Plants, Medicinal; Rats; Receptors, Drug | 1969 |
[On the determination of cardiotoxicity of cardiac glycosides in cats. 1. General bases and biophysical model for intravenous and intraduodenal infusion experiments].
Topics: Animals; Cardiac Glycosides; Cats; Digitoxin; Digoxin; Electrocardiography; Female; Heart; Injections, Intravenous; Intestinal Absorption; Male; Models, Biological; Ouabain | 1969 |
Effects of cardiac glycosides on spontaneous efferent activity in vagus and sympathetic nerves of cats.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Glycosides; Cats; Digitoxin; Electrophysiology; Female; Heart Rate; Injections, Intravenous; Male; Neural Conduction; Neurons; Neurons, Efferent; Ouabain; Stellate Ganglion; Sympathetic Nervous System; Vagus Nerve | 1969 |
Inhibition of active intestinal sugar transport by digitalis.
Topics: Animals; Anura; Biological Transport, Active; Cardiac Glycosides; Digitalis; Digitoxin; Hexoses; In Vitro Techniques; Intestine, Small; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium | 1965 |
[The potency, onset of action, detoxication and absorption from gastrointestinal tract of the several kinds of digitalis].
Topics: Animals; Anura; Cats; Digitalis Glycosides; Digitoxin; Heart; Intestinal Absorption; Lanatosides; Ouabain | 1965 |
[Pharmacological properties of acetyldigoxin-alpha].
Topics: Animals; Birds; Cats; Digitoxin; Electrocardiography; Guinea Pigs; Heart; Heart Atria; Injections, Intravenous; Intestinal Absorption; Lanatosides; Ouabain | 1966 |
[On the effect of various digitalis substances on monoamine oxidase activity in rat, guinea pig and cat brain].
Topics: Animals; Brain; Cardanolides; Cats; Digitoxin; Dopamine; Female; Guinea Pigs; Hormones; Indoles; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Ouabain; Oxygen Consumption; Pyridines; Rats; Serotonin; Tryptamines; Tyramine | 1966 |
[The digitalis effect and noradrenaline].
Topics: Animals; Brain; Cardanolides; Digitoxin; Female; Guinea Pigs; Myocardium; Norepinephrine; Ouabain; Rats; Reserpine | 1966 |
[Determination of protein binding of digitalis preparations by means of the ultracentrifuge].
Topics: Blood Proteins; Digitalis Glycosides; Digitoxin; Digoxin; Humans; Ouabain; Plants, Medicinal; Protein Binding; Sulfonamides; Ultracentrifugation | 1966 |
The capacity of different digitalis materials to induce ventricular rhythm disturbances in the reserpine-pretreated cat.
Topics: Animals; Arrhythmias, Cardiac; Cats; Digitalis Glycosides; Digitoxin; Digoxin; Female; Lanatosides; Male; Ouabain; Reserpine; Vagus Nerve; Ventricular Fibrillation | 1967 |
Mathematical interpretation of heart kymography.
Topics: Animals; Cardiac Glycosides; Digitoxin; Heart; Kymography; Male; Mathematics; Ouabain; Rats | 1967 |
Cardiac properties of the delta-1,4-3-oxo- derivative of digitoxigenin.
Topics: Animals; Cardiac Glycosides; Digitalis Glycosides; Digitoxin; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Male; Ouabain | 1967 |
Demonstration of enhanced lethality of drugs in hypoexcretory animals.
Topics: Animals; Anuria; Bile; Bile Ducts; Biliary Tract Diseases; Digitoxin; Digoxin; Drug Tolerance; Fluorescence; Lanatosides; Male; Mice; Ouabain | 1967 |
Photoaffinity labeling of the ouabain binding site in Na, K-ATPase in developing brine shrimp.
Topics: Affinity Labels; Animals; Artemia; Binding Sites; Diazonium Compounds; Digitoxigenin; Digitoxin; Electrophoresis, Polyacrylamide Gel; Ouabain; Sodium-Potassium-Exchanging ATPase | 1984 |
Ouabain-binding-site photoaffinity probes that label both subunits of Na+,K+-ATPase.
Topics: Affinity Labels; Animals; Binding Sites; Diazonium Compounds; Digitoxin; Electrophorus; Macromolecular Substances; Ouabain; Photochemistry; Sodium-Potassium-Exchanging ATPase | 1980 |
A comparison of inotropic actions of p-chloromercuribenzoate, ouabain, digitoxin and digitoxigenin.
Topics: Animals; Binding Sites; Cell Membrane; Chloromercuribenzoates; Digitoxigenin; Digitoxin; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Rate; Myocardial Contraction; Ouabain; p-Chloromercuribenzoic Acid; Sodium-Potassium-Exchanging ATPase | 1982 |
The cardiac glycoside-receptor system in the human heart.
Topics: Animals; Binding Sites; Cats; Cell Membrane; Cells, Cultured; Digitoxin; Digoxin; Guinea Pigs; Humans; Hypokalemia; Myocardial Infarction; Myocardium; Ouabain; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Thyroid Diseases | 1983 |
Digitalis structure-activity relationship analyses. Conclusions from indirect binding studies with cardiac (Na+ + K+)-ATPase.
Topics: Animals; Binding, Competitive; Cattle; Digitalis Glycosides; Digitoxin; Guinea Pigs; Myocardial Contraction; Myocardium; Ouabain; Protein Binding; Sodium-Potassium-Exchanging ATPase; Species Specificity; Structure-Activity Relationship | 1983 |
Binding of dihydrodigitoxin to beef and human cardiac (Na+ + K+)-ATPase: evidence for two binding sites in cell membranes.
Topics: Animals; Cattle; Cell Membrane; Digitoxin; Humans; In Vitro Techniques; Kinetics; Myocardium; Ouabain; Protein Binding; Receptors, Drug; Sodium-Potassium-Exchanging ATPase | 1983 |
ATP-energized Ca2+ pump in isolated transverse tubules of skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Digitoxin; In Vitro Techniques; Monensin; Muscles; Organoids; Ouabain; Oxalates; Rabbits; Sarcoplasmic Reticulum; Subcellular Fractions | 1980 |
A methodical pitfall: saturable binding of digitoxin to glass-fibre filters.
Topics: Animals; Binding Sites; Digitoxin; Filtration; Glass; Guinea Pigs; In Vitro Techniques; Myocardium; Ouabain; Tritium | 1984 |
Hypotensive effects of cardiac glycosides in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiac Glycosides; Digitoxin; Hypertension; Injections, Intra-Arterial; Injections, Intraperitoneal; Intubation, Gastrointestinal; Male; Ouabain; Pressoreceptors; Rats | 1980 |
Uptake, accumulation and release of ouabain by isolated rat hepatocytes.
Topics: Animals; Digitoxin; Glycosides; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Ouabain; Rats; Sodium; Temperature; Time Factors | 1981 |
Transport systems of isolated hepatocytes. Studies on the transport of biliary compounds.
Topics: Animals; Bile Acids and Salts; Biological Transport, Active; Cell Membrane; Cholic Acids; Digitoxin; Glucuronates; In Vitro Techniques; Liver; Male; Naphthols; Ouabain; Rats; Time Factors | 1980 |
Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism.
Topics: Animals; Caprylates; Cells, Cultured; Chick Embryo; Digitoxin; Energy Metabolism; Glucose; Glycolysis; Heart; Lactates; Lactic Acid; Muscle Proteins; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid | 1994 |
In vitro scanning saturation mutagenesis of an antibody binding pocket.
Topics: Binding Sites, Antibody; Digitoxin; Digoxigenin; Digoxin; Ligands; Mutagenesis; Ouabain; Polymerase Chain Reaction; Protein Binding; Recombinant Proteins; Structure-Activity Relationship | 1997 |
Involvement of a peripheral mechanism in the emesis induced by cardiac glycosides in Suncus murinus.
Topics: Animals; Antiemetics; Cardiac Glycosides; Digitonin; Digitoxin; Female; Indoles; Injections, Intraperitoneal; Injections, Intraventricular; Male; Ouabain; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Shrews; Tropisetron; Vagotomy; Vomiting | 1997 |
High-performance liquid chromatography-ionspray mass spectrometry for the specific determination of digoxin and some related cardiac glycosides in human plasma.
Topics: Acetyldigitoxins; Cardiac Glycosides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Digitoxin; Digoxin; Gas Chromatography-Mass Spectrometry; Humans; Lanatosides; Ouabain; Sensitivity and Specificity | 1997 |
Synthetic candidates for EDLF. Activity on human placenta digitalis receptors.
Topics: Cardenolides; Cell Membrane; Digitoxin; Digoxin; Enzyme Inhibitors; Estradiol Congeners; Female; Humans; Iodine Radioisotopes; Kinetics; Ouabain; Placenta; Pregnancy; Radioligand Assay; Saponins; Sodium-Potassium-Exchanging ATPase; Tritium | 1997 |
Exogenous ouabain is accumulated in the adrenals and mimics the kinetics of endogenous digitalis-like factor in rats.
Topics: Adrenal Cortex; Adrenalectomy; Animals; Autoradiography; Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Cross Reactions; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Kidney; Kinetics; Nephrectomy; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saponins; Tissue Distribution; Tritium | 1998 |
In vitro scanning saturation mutagenesis of all the specificity determining residues in an antibody binding site.
Topics: Amino Acids; Antibody Specificity; Binding Sites, Antibody; Digitoxin; Digoxigenin; Digoxin; Enzyme-Linked Immunosorbent Assay; Immunoglobulin Fragments; Kinetics; Models, Molecular; Mutagenesis; Ouabain; Polymerase Chain Reaction; Protein Biosynthesis; Surface Plasmon Resonance; Transcription, Genetic | 1999 |
Inhibition of testosterone secretion by digitoxin in rat testicular interstitial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Digitoxin; Humans; Male; Ouabain; Rats; Rats, Sprague-Dawley; Testis; Testosterone | 1999 |
Non-absorption of ingested lipophilic and amphiphilic allelochemicals by generalist grasshoppers: the role of extractive ultrafiltration by the peritrophic envelope.
Topics: Animals; Chromatography, High Pressure Liquid; Digitoxin; Enzyme Inhibitors; Grasshoppers; Lysophosphatidylcholines; Methoxsalen; Micelles; Ouabain; Permeability; Ultrafiltration | 1999 |
Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin.
Topics: Aldosterone; Animals; Blood Pressure; Cardiotonic Agents; Chronic Disease; Digitoxin; Digoxin; Hypertension, Renal; Kidney; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Tissue Distribution | 2000 |
Direct inhibitory effect of digitalis on progesterone release from rat granulosa cells.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Cardiotonic Agents; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Cyclic AMP; Digitalis Glycosides; Digitoxin; Digoxin; Enzyme Inhibitors; Female; Granulosa Cells; In Vitro Techniques; Membrane Proteins; Ouabain; Ovary; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2001 |
Emesis and space motion sickness in amphibians.
Topics: Amphibians; Animals; Anura; Apomorphine; Cisplatin; Digitoxin; Emetics; Hypergravity; Ouabain; Reproducibility of Results; Space Flight; Space Motion Sickness; Urodela; Vomiting; Weightlessness | 2000 |
Inhibitory effects of digitalis on the proliferation of androgen dependent and independent prostate cancer cells.
Topics: Apoptosis; Cell Division; Colorimetry; Digitalis Glycosides; Digitoxin; Digoxin; Enzyme Inhibitors; Humans; Male; Ouabain; Prostatic Neoplasms; Tumor Cells, Cultured | 2001 |
Progesterone attenuates the inhibitory effects of cardiotonic digitalis on pregnenolone production in rat luteal cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenylyl Cyclases; Animals; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP; Digitalis Glycosides; Digitoxin; Digoxin; Female; Hormone Antagonists; Leydig Cells; Luteal Cells; Male; Mifepristone; Ouabain; Phosphoproteins; Pregnenolone; Progesterone; Rats | 2002 |
Interactions of cationic drugs and cardiac glycosides at the hepatic uptake level: studies in the rat in vivo, isolated perfused rat liver, isolated rat hepatocytes and oocytes expressing oatp2.
Topics: Animals; Bile; Cardiac Glycosides; Cations; Digitoxin; Drug Interactions; Hepatocytes; In Vitro Techniques; Kinetics; Liver; Liver-Specific Organic Anion Transporter 1; Male; Oocytes; Ouabain; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Strophanthins; Tubocurarine; Xenopus laevis | 2002 |
[Enteral resorption of g-strophanthin, k-strophanthol-gamma and digitoxin in cat].
Topics: Animals; Biological Phenomena; Cardiac Glycosides; Cats; Digitoxin; Felis; Gamma Rays; Glycosides; Humans; Ouabain; Physiological Phenomena | 1952 |
Effects of dihydro-ouabain, dihydrodigoxin and dihydrodigitoxin on the heart-lung preparation of the dog.
Topics: Animals; Digitalis; Digitoxin; Digoxin; Dogs; Heart; Ouabain; Strophanthins | 1957 |
The duration of action of some cardiac glycosides and aglycones in the guinea-pig.
Topics: Biological Transport; Cardiac Glycosides; Digitalis Glycosides; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin; Guinea Pigs; Heart; Humans; Lanatosides; Ouabain | 1959 |
GRAVIMETRIC EVALUATION OF PAPER CHROMATOGRAMS. II. STUDIES ON OUABAIN, OTHER GLYCOSIDES, AND PREDNISONE.
Topics: Chemistry, Pharmaceutical; Chromatography; Digitoxin; Glycosides; Ouabain; Pharmacy; Prednisone; Research; Strophanthins | 1963 |
THE OCULAR EFFECTS OF TOPICAL DIGITALIS.
Topics: Cornea; Digitalis; Digitalis Glycosides; Digitoxin; Dogs; Eye; Intraocular Pressure; Ointments; Ophthalmic Solutions; Ouabain; Rabbits; Research; Strophanthins; Tonometry, Ocular; Toxicology | 1963 |
[START OF EFFECT AND LONG-ACTING EFFECT OF CARDIAC GLYCOSIDES].
Topics: Animals; Cardiac Glycosides; Digitoxin; Myocardium; Ouabain; Pharmacology; Research; Sheep; Sheep, Domestic; Strophanthins | 1963 |
[ON THE SCILLAREN B UPTAKE BY LIVER OF CATS AND GUINEA-PIGS].
Topics: Animals; Cardiac Glycosides; Cats; Chick Embryo; Digitoxin; Expectorants; Guinea Pigs; Lanatosides; Liver; Liver Circulation; Metabolism; Ouabain; Perfusion; Plants, Medicinal; Research | 1963 |
THE MODIFICATION OF DIGITALIS INTOXICATION BY EXCLUDING ADRENERGIC INFLUENCES ON THE HEART.
Topics: Adrenalectomy; Adrenergic Agents; Cats; Digitalis; Digitoxin; Dogs; Heart; Norepinephrine; Ouabain; Pharmacology; Research; Reserpine; Sympathectomy; Sympatholytics; Toxicology | 1964 |
EFFECTS OF STEROIDS ON THE COURSE OF HEREDITARY MUSCULAR DYSTROPHY IN MICE.
Topics: Adenosine Triphosphate; Aldosterone; Alkaloids; Anabolic Agents; Animals; Calcium; Chlorides; Coenzymes; Cortisone; Creatine; Creatinine; Desoxycorticosterone; Digitoxin; Estradiol; Genetics; Hydroxyprogesterones; Magnesium; Methyltestosterone; Mice; Muscles; Muscular Dystrophies; Norethandrolone; Ouabain; Pharmacology; Phosphocreatine; Potassium; Research; Sodium; Steroids; Testosterone | 1964 |
A COMPARISON OF DIHYDRO-OUABAIN, DIHYDRODIGOXIN, DIHYDRODIGITOXIN, 3-ACETYL STROPHANTHIDIN, ERYSIMIN, AND OUABAIN GIVEN BY CONTINUOUS INFUSION INTO DOGS.
Topics: Animals; Cardiac Glycosides; Digitalis Glycosides; Digitoxin; Digoxin; Dogs; Infusions, Parenteral; Ouabain; Pharmacology; Research; Strophanthidin; Strophanthins | 1964 |
[ON THE PHARMACOLOGY OF A PURE GLYCOSIDE RECENTLY INTRODUCED INTO THERAPY].
Topics: Cardiac Glycosides; Cats; Digitoxin; Glycosides; Guinea Pigs; Heart; Ouabain; Pharmacology; Plants, Medicinal; Research; Toxicology | 1964 |
[RELATIONSHIP BETWEEN THE INFLUENCE OF NERIIFOLIN, OUABAIN AND DIGITOXIN ON THE POTASSIUM TRANSPORT IN HUMAN ERYTHROCYTES AND THEIR LETHAL EFFECTS ON GUINEA PIGS].
Topics: Animals; Cardenolides; Cardiac Glycosides; Digitoxin; Erythrocytes; Guinea Pigs; Metabolism; Ouabain; Potassium; Research; Toxicology | 1965 |
[THE PHARMACOLOGY OF OLEANDRIN COMPARED WITH G-STROPHANTHIN, DIGOXIN AND DIGITOXIN].
Topics: Cardenolides; Digitoxin; Digoxin; Nerium; Ouabain; Research | 1965 |
A BIOLOGICAL ASSAY METHOD FOR CARDIOTONIC STEROIDS, USING FROG RECTUS ABDOMINIS MUSCLE.
Topics: Animals; Anura; Biological Assay; Calcium; Calcium, Dietary; Cardiac Glycosides; Digitoxin; Digoxin; Heart; Muscle Contraction; Ouabain; Pharmacology; Rectus Abdominis; Research | 1965 |
Evidence for an intracellular site of action in the heart for two hydrophobic cardiac steroids.
Topics: Animals; Blood Pressure; Calcium; Cardiotonic Agents; Chemical Phenomena; Chemistry, Physical; Digitoxin; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Ouabain; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Steroids; Ventricular Function, Left | 2004 |
[Enteral resorption of g-strophanthin K-strophanthol gamma and digitoxin in the cat].
Topics: Animals; Cats; Digitalis; Digitalis Glycosides; Digitoxin; Felis; Ouabain; Strophanthins | 1952 |
Inhibitory effects of digoxin and digitoxin on corticosterone production in rat zona fasciculata-reticularis cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Corticosterone; Digitoxin; Digoxin; Male; Ouabain; Rats; Rats, Sprague-Dawley; Zona Fasciculata; Zona Reticularis | 2004 |
Mechanisms of digoxin and digitoxin on the production of corticosterone in zona fasciculata-reticularis cells of ovariectomized rats.
Topics: Adrenal Cortex; Animals; Calcium; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cyclic AMP; Digitalis Glycosides; Digitoxin; Digoxin; Female; Luteal Cells; Ouabain; Ovariectomy; Phosphoproteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroids | 2006 |
Validation of a Rb+ uptake assay for the mouse embryonic stem cell-derived cardiomyocytes Na+, K+ ATPase.
Topics: Animals; Cells, Cultured; Digitoxin; High-Throughput Screening Assays; Mice; Myocytes, Cardiac; Ouabain; Rubidium; Sodium-Potassium-Exchanging ATPase; Stem Cells | 2010 |
Cardiac glycosides potently inhibit C-reactive protein synthesis in human hepatocytes.
Topics: Adult; C-Reactive Protein; Calcium; Cardiac Glycosides; Cell Line, Tumor; Cells, Cultured; Digitoxin; Female; Hepatocytes; Humans; Interleukin-1beta; Interleukin-6; Male; Middle Aged; Ouabain; Promoter Regions, Genetic; Transcription, Genetic | 2010 |
Cardiac glycosides decrease prostate specific antigen expression by down-regulation of prostate derived Ets factor.
Topics: Cardiac Glycosides; Cardiotonic Agents; Digitoxin; Digoxin; Down-Regulation; Gene Expression Regulation; Humans; Male; Ouabain; Prostate-Specific Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins c-ets; Tumor Cells, Cultured | 2010 |
The determination of the minimal lethal dose and the average rate of uptake of G-strophantin and digitoxin in the heart-lung preparation of the dog.
Topics: Animals; Digitalis; Digitoxin; Dogs; Drug-Related Side Effects and Adverse Reactions; Heart; Ouabain; Strophanthins | 1946 |
Human cytomegalovirus inhibition by cardiac glycosides: evidence for involvement of the HERG gene.
Topics: Animals; Antiviral Agents; Cardiac Glycosides; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cytomegalovirus; Digitoxin; Digoxin; Ether-A-Go-Go Potassium Channels; Fibroblasts; Gene Expression; Genes, Reporter; Humans; Mice; NF-kappa B; Ouabain; Transcriptional Activation; Viral Proteins; Virus Replication | 2012 |
In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of Action.
Topics: Antiviral Agents; Artemisinins; Butadienes; Cell Line; Cytomegalovirus; Digitoxin; Digoxin; Drug Combinations; Drug Interactions; Fibroblasts; Foscarnet; Ganciclovir; Humans; Indoles; Nitriles; Ouabain; Pyrroles; Sunitinib; Virus Replication | 2014 |
Ouabain inhibits placental sFlt1 production by repressing HSP27-dependent HIF-1α pathway.
Topics: Animals; Blood Pressure; Cardenolides; Cardiotonic Agents; Cells, Cultured; Digitoxin; Dose-Response Relationship, Drug; Female; HSP27 Heat-Shock Proteins; Humans; Hypertension, Pregnancy-Induced; Hypoxia-Inducible Factor 1, alpha Subunit; Ouabain; Phosphorylation; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Endothelial Growth Factor Receptor-1 | 2014 |
Peruvoside, a Cardiac Glycoside, Induces Primitive Myeloid Leukemia Cell Death.
Topics: Antineoplastic Agents; Apoptosis; Cardenolides; Cardiac Glycosides; Caspase 3; Caspase 8; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Digitoxin; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Leukemia, Myeloid; Neoplastic Stem Cells; Ouabain; Poly(ADP-ribose) Polymerases | 2016 |
Cardiac glycosides display selective efficacy for STK11 mutant lung cancer.
Topics: A549 Cells; AMP-Activated Protein Kinase Kinases; Animals; Cardiac Glycosides; Cardiotonic Agents; Cell Line, Tumor; Digitoxin; Digoxin; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice, Nude; Mutation; Ouabain; Protein Serine-Threonine Kinases; RNA Interference; Xenograft Model Antitumor Assays | 2016 |
Pharmacological targeting of p38 MAP-Kinase 6 (MAP2K6) inhibits the growth of esophageal adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cell Proliferation; Digitoxin; Digoxin; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Humans; MAP Kinase Kinase 6; Mice, Inbred NOD; Ouabain; Protein Kinase Inhibitors; Signal Transduction; SOX9 Transcription Factor; Xenograft Model Antitumor Assays | 2018 |
Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells.
Topics: A549 Cells; Angiotensin-Converting Enzyme 2; Animals; Cardiotonic Agents; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Digitoxin; Digoxin; Humans; Lung; Ouabain; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vero Cells; Virus Internalization | 2021 |
In Silico Study towards Repositioning of FDA-Approved Drug Candidates for Anticoronaviral Therapy: Molecular Docking, Molecular Dynamics and Binding Free Energy Calculations.
Topics: Antiviral Agents; COVID-19; Cysteine Endopeptidases; Digitoxin; Digoxin; Drug Repositioning; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Niclosamide; Ouabain; Papain; Proscillaridin; RNA-Dependent RNA Polymerase; SARS-CoV-2 | 2022 |
Nonuniform cardiac sympathetic nerve discharge: mechanism for coronary occlusion and digitalis-induced arrhythmia.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Blood Pressure; Cats; Coronary Vessels; Digitalis; Heart; Heart Conduction System; Heart Rate; Ouabain; Plants, Medicinal; Plants, Toxic; Sympathetic Nervous System; Time Factors | 1978 |
Elevated endogenous digitalis-like substance in hypertensive diabetic patients with a family history of hypertension.
Topics: Aged; Albuminuria; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Digitalis; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium-Potassium-Exchanging ATPase | 1991 |
[Enhancement of susceptibility to ouabain in ischemic rat heart].
Topics: Animals; Coronary Disease; Digitalis; Hemodynamics; Ion Channels; Male; Myocardial Reperfusion Injury; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Rats; Rats, Inbred Strains; Sodium | 1991 |
Some substances with proposed digitalis-like effects evaluated on platelet functions sensitive for cardiac glycosides.
Topics: Blood Platelets; Cardiac Glycosides; Chlormadinone Acetate; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Digitalis; Digoxin; Humans; In Vitro Techniques; Lysophosphatidylcholines; Ouabain; Plants, Medicinal; Plants, Toxic; Platelet Aggregation; Progesterone; Rubidium; Serotonin; Sodium-Potassium-Exchanging ATPase | 1991 |
Binding properties and biological effects of oxidized-ouabain on cultured neonatal-rat cardiac myocytes. Implications on the mechanism of action of the digitalis-glycosides.
Topics: Animals; Animals, Newborn; Calcium; Cardiac Glycosides; Cells, Cultured; Digitalis; Dose-Response Relationship, Drug; Myocardium; Ouabain; Oxidation-Reduction; Plants, Medicinal; Plants, Toxic; Potassium; Rats; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase | 1991 |
Partial purification of endogenous digitalis-like compound(s) in cord blood.
Topics: Adult; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Cross Reactions; Digitalis; Digoxin; Fetal Blood; Humans; Infant, Newborn; Ouabain; Plants, Medicinal; Plants, Toxic; Radioimmunoassay; Rubidium Radioisotopes; Saponins | 1991 |
Role of sarcoplasmic reticulum in digitalis-induced electrical and mechanical oscillations in the heart.
Topics: Animals; Caffeine; Calcium; Cardiac Complexes, Premature; Digitalis; Dogs; Female; Heart Ventricles; Male; Manganese; Myocardial Contraction; Ouabain; Plants, Medicinal; Plants, Toxic; Ryanodine; Sarcoplasmic Reticulum | 1987 |
Sodium pump inhibitor in the serum of patients with essential hypertension and its partial purification from hemofiltrate.
Topics: Animals; Blood; Blood Pressure; Brain; Cattle; Digitalis; Humans; Hypertension; Ion Channels; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium; Ultrafiltration | 1987 |
Digitalis-like properties of an inhibitor of the Na+/K+ pump in human cerebrospinal fluid.
Topics: Adult; Binding, Competitive; Digitalis; Enzyme Inhibitors; Erythrocyte Membrane; Humans; Infant; Molecular Weight; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium-Potassium-Exchanging ATPase; Thermolysin | 1989 |
Facilitatory effects of ouabain and digitalis-like substance on adrenergic transmission in hypertension.
Topics: Animals; Blood Pressure; Digitalis; Hypertension; Male; Nephrectomy; Norepinephrine; Ouabain; Plants, Medicinal; Plants, Toxic; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium Chloride; Splanchnic Circulation; Sympathetic Nervous System; Synaptic Transmission | 1989 |
Affinity labeling of the digitalis-binding site.
Topics: Affinity Labels; Animals; Binding Sites; Cardiac Glycosides; Digitalis; Indicators and Reagents; Kinetics; Macromolecular Substances; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship | 1988 |
Characterization of digitalis-like factors in human plasma. Interactions with NaK-ATPase and cross-reactivity with cardiac glycoside-specific antibodies.
Topics: Adenosine Triphosphate; Antibodies; Cardiac Glycosides; Chromatography, High Pressure Liquid; Cross Reactions; Digitalis; Humans; Hydrogen-Ion Concentration; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium; Sodium-Potassium-Exchanging ATPase | 1985 |
Dehydroepiandrosterone sulfate as a digitalis like factor in plasma of healthy human adults.
Topics: Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Digitalis; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium-Potassium-Exchanging ATPase | 1985 |
Effects of cytochalasin-B and phloretin on digitalis inotropy.
Topics: Animals; Cytochalasin B; Digitalis; Drug Interactions; Female; Isoproterenol; Male; Myocardial Contraction; Ouabain; Phloretin; Plants, Medicinal; Plants, Toxic; Rabbits; Sarcolemma; Strophanthidin | 1988 |
Enhancement of triggered activity in ischemic Purkinje fibers by ouabain: a mechanism of increased susceptibility to digitalis toxicity in myocardial infarction.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Coronary Disease; Digitalis; Dogs; Dose-Response Relationship, Drug; Heart Conduction System; Isotonic Solutions; Myocardial Infarction; Ouabain; Perfusion; Plants, Medicinal; Plants, Toxic; Purkinje Fibers; Time Factors | 1985 |
Recent advances on endogenous Na+,K+-ATPase inhibitors: clinical investigation and purification.
Topics: Acromegaly; Animals; ATPase Inhibitory Protein; Binding Sites; Brain; Digitalis; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Kinetics; Ouabain; Plants, Medicinal; Plants, Toxic; Proteins; Swine | 1985 |
A possible biochemical explanation for the insensitivity of the rat to cardiac glycosides.
Topics: Adenosine Triphosphatases; Animals; Cardiac Glycosides; Cattle; Digitalis; Dogs; Kidney; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Protein Binding; Rats; Sodium; Species Specificity; Temperature; Time Factors; Tritium | 1969 |
Nature of the transport adenosine triphosphatase digitalis complex. IV. Evidence that sodium-potassium competition modulates the rate of ouabain interaction iwth (Na + +K + ) adenosine triphosphatase during enzyme catalysis.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Catalysis; Cattle; Cerebral Cortex; Chlorides; Digitalis; Dogs; Kidney Cortex; Kinetics; Magnesium; Mathematics; Models, Chemical; Osmolar Concentration; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Protein Binding; Sodium; Tritium; Tromethamine | 1973 |
Drug therapy of heart disease in pediatric patients. II. The treatment of congestive heart failure in infants and children with digitalis preparations.
Topics: Adenosine Triphosphatases; Adolescent; Adult; Age Factors; Animals; Calcium; Cell Membrane; Child; Child, Preschool; Digitalis; Digitalis Glycosides; Digoxin; Heart Failure; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kidney Diseases; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium; Tritium | 1973 |
Na+, K+-ATPase, the transport enzyme: evidence for its proposed role as pharmacologic receptor for cardiac glycosides.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Digitalis; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Enzyme Activation; Heart; Humans; Kinetics; Magnesium; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Protein Binding; Sodium; Species Specificity; Spectrophotometry, Ultraviolet; Stimulation, Chemical; Time Factors; Tritium | 1974 |
Inhibition of Na+, K+-ATPase and digitalis action: dissociation from inotropic effects and its role in digitalis cardiotoxicity.
Topics: Acetylcholine; Adenosine Triphosphatases; Aldosterone; Animals; Digitalis; Digoxin; Dimethylformamide; Enzyme Activation; Half-Life; Heart; Kinetics; Microsomes; Myocardium; Ouabain; Perfusion; Plants, Medicinal; Plants, Toxic; Potassium; Rabbits; Sodium; Stimulation, Chemical; Strophanthidin; Time Factors; Tritium | 1974 |
Use of antibodies in the study of the mechanism of action of digitalis.
Topics: Adenosine Triphosphatases; Animals; Antibodies; Binding Sites; Digitalis; Dogs; Electrocardiography; Enzyme Activation; Heart; Immunoglobulin Fab Fragments; Kinetics; Microsomes; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Protein Binding; Sodium; Strophanthidin; Tachycardia; Time Factors | 1974 |
Glycoside effects on ionic exchange in perfused mammalian heart.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Calcium; Digitalis; Heart; Models, Biological; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Potassium; Potassium Isotopes; Radioisotopes; Rats; Sarcolemma; Sodium; Temperature; Time Factors | 1974 |
Digitalis in the sick sinus syndrome. The effects of digitalis on sinoatrial automaticity and atrioventricular conduction.
Topics: Aged; Arrhythmia, Sinus; Atropine; Digitalis; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Sinoatrial Node; Syncope | 1973 |
The paced human heart. II. Hemodynamic and ballistocardiographic correlations after digitalis administation.
Topics: Aged; Ballistocardiography; Blood Pressure; Brachial Artery; Cardiac Output; Digitalis; Electrocardiography; Heart; Heart Block; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Middle Aged; Ouabain; Pacemaker, Artificial; Phytotherapy; Plants, Medicinal; Plants, Toxic; Vascular Resistance | 1973 |
The influence of sympathetic nervous activity on the antiarrhythmic efficacy of diphenylhydantoin.
Topics: Animals; Blood Pressure; Cats; Digitalis; Heart Rate; Heart Ventricles; Ouabain; Phenytoin; Plants, Medicinal; Plants, Toxic; Spinal Cord; Sympathetic Nervous System; Tachycardia | 1970 |
The capacity of N-isopropyl-p-nitro-phenylethanolamine (INPEA) to influence the course of ouabain-induced cardiotoxicity in the cat.
Topics: Animals; Blood Pressure; Carotid Arteries; Cats; Depression, Chemical; Digitalis; Heart Rate; Nerve Endings; Ouabain; Phenethylamines; Plants, Medicinal; Plants, Toxic; Sympatholytics | 1969 |
Cardiovascular function, oxygen extraction and labile nucleotide content of cardiac muscle during norepinephrine-induced depression of digitalized, hypothermic dog heart muscle.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Digitalis; Dogs; Heart; Hypothermia, Induced; Myocardium; Norepinephrine; Ouabain; Oxygen; Phosphocreatine; Plants, Medicinal; Plants, Toxic | 1966 |
Investigation of the endogenous Na+-pump inhibitor in essential hypertension and blood volume expansion.
Topics: Acromegaly; Adult; Animals; ATPase Inhibitory Protein; Blood Proteins; Blood Volume; Digitalis; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Kidney Failure, Chronic; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Proteins; Rats; Receptors, Drug; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
Mechanism of action of digitalis: is the Na,K-ATPase the pharmacological receptor?
Topics: Animals; Binding Sites; Brain; Calcium-Transporting ATPases; Digitalis; Digitalis Glycosides; Heart; Kinetics; Myocardial Contraction; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Protein Binding; Rabbits; Rats; Receptors, Drug; Sodium-Potassium-Exchanging ATPase | 1982 |
[3H]serotonin uptake in human blood platelets is reduced by ouabain and endogenous digitalis-like inhibitors of Na+, K+-ATPase.
Topics: Blood Platelets; Digitalis; Humans; In Vitro Techniques; Ouabain; Plants, Medicinal; Plants, Toxic; Serotonin; Sodium-Potassium-Exchanging ATPase | 1983 |
Identification of the segment of the catalytic subunit of (Na+,K+)ATPase containing the digitalis binding site.
Topics: Animals; Digitalis; Dogs; Kidney Medulla; Macromolecular Substances; Molecular Weight; Ouabain; Peptide Fragments; Phosphorylation; Plants, Medicinal; Plants, Toxic; Protein Binding; Protein Conformation; Rabbits; Sodium-Potassium-Exchanging ATPase | 1982 |
Effects of metoprolol on digitalis-resistant atrial tachyarrhythmias in chronic obstructive pulmonary disease.
Topics: Aged; Digitalis; Drug Therapy, Combination; Female; Heart Rate; Humans; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Tachycardia; Verapamil | 1984 |
Amiloride: relationship between cardiac effects and inhibition of Na+/Ca2+ exchange.
Topics: Amiloride; Animals; Calcium; Cattle; Digitalis; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Ouabain; Plants, Medicinal; Plants, Toxic; Pyrazines; Sarcolemma; Sodium | 1984 |
Effects of digitalis on subendocardial and subepicardial dysfunction during acute ischemia.
Topics: Animals; Arterial Occlusive Diseases; Coronary Circulation; Coronary Disease; Digitalis; Dogs; Myocardial Contraction; Ouabain; Plants, Medicinal; Plants, Toxic; Ultrasonography | 1982 |
Digitalis receptor desensitization in rat ventricle: ouabain produces two inotropic effects.
Topics: Animals; Atrial Function; Digitalis; Heart; Kinetics; Myocardial Contraction; Ouabain; Plants, Medicinal; Plants, Toxic; Rats; Receptors, Drug; Reserpine; Sodium-Potassium-Exchanging ATPase; Ventricular Function | 1981 |
A sensitive [Na,K]ATPase assay specific for inhibitors acting through the digitalis-binding site.
Topics: Animals; Antineoplastic Agents; Binding, Competitive; Bufanolides; Cattle; Digitalis; Digoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kidney; Lysophosphatidylcholines; Oleic Acid; Oleic Acids; Ouabain; Plants, Medicinal; Plants, Toxic; Regression Analysis; Silver Nitrate; Sodium-Potassium-Exchanging ATPase; Steroids; Tamoxifen; Vanadates | 1995 |
Identification of digitalis-like compounds in human cataractous lenses.
Topics: Animals; Antibodies; Blood Proteins; Bufanolides; Cardenolides; Cataract; Digitalis; Digoxin; Humans; Lens Nucleus, Crystalline; Mass Spectrometry; Microsomes; Molecular Weight; Ouabain; Plants, Medicinal; Plants, Toxic; Rats; Saponins; Sodium-Potassium-Exchanging ATPase | 1993 |
Effects of uremic serum on isolated cardiac myocyte calcium cycling and contractile function.
Topics: Adult; Animals; Antibodies; Blood Physiological Phenomena; Calcium; Cell Separation; Cells, Cultured; Digitalis; Dogs; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Contraction; Myocardium; Ouabain; Rats; Rats, Sprague-Dawley; Rubidium; Sodium-Potassium-Exchanging ATPase; Uremia | 2001 |
A comparison of the direct peripheral actions upon systemic venous pressure of k-strophanthosid, digoxin and ouabain.
Topics: Blood Pressure; Blood Pressure Determination; Digitalis; Digitalis Glycosides; Digoxin; Ouabain; Pressure; Strophanthins; Venous Pressure | 1953 |
[Cardiac effect of a quinoxaline derivative in comparison with g-strophantin, cristafolin and monoiodoacetic acid].
Topics: Digitalis; Digitalis Glycosides; Heart; Iodoacetic Acid; Ouabain; Quinolines; Quinoxalines; Strophanthins | 1953 |
[Simultaneous use of digitalis with ouabain: 108 cases].
Topics: Cardiotonic Agents; Digitalis; Digitalis Glycosides; Enzyme Inhibitors; Heart Diseases; Ouabain; Strophanthins | 1954 |
The action of strophanthin-G and digoxin on energy production in the isolated toad heart.
Topics: Animals; Bufonidae; Digitalis; Digitalis Glycosides; Digoxin; Heart; Ouabain; Strophanthins | 1956 |
Digoxin, ouabain and potassium movements in rabbit auricles.
Topics: Animals; Digitalis; Digitalis Glycosides; Digoxin; Myocardium; Ouabain; Potassium; Rabbits; Sodium; Strophanthins | 1957 |
[Place of ouabain among the drugs with digitalis-like effect].
Topics: Digitalis; Digitalis Glycosides; Ouabain; Strophanthins | 1959 |
Studies on digitalis. V. Comparison of the effects of ouabain on left ventricular dynamics in valvular aortic stenosis and hypertrophic subaortic stenosis.
Topics: Aortic Valve Stenosis; Cardiomyopathy, Hypertrophic; Constriction, Pathologic; Digitalis; Heart Ventricles; Humans; Ouabain; Strophanthins | 1962 |
[PROBLEMS INHERENT TO DIGITALIS THERAPY IN THE NEWBORN INFANT].
Topics: Digitalis; Digitalis Glycosides; Digoxin; Electrocardiography; Infant, Newborn; Infant, Premature; Ouabain; Rabbits; Research; Strophanthins; Toxicology | 1963 |
STUDIES ON DIGITALIS. X. EFFECTS OF OUABAIN ON FOREARM VASCULAR RESISTANCE AND VENOUS TONE IN NORMAL SUBJECTS AND IN PATIENTS IN HEART FAILURE.
Topics: Blood Flow Velocity; Digitalis; Forearm; Guanethidine; Heart Failure; Humans; Ouabain; Pharmacology; Plethysmography; Strophanthins; Vascular Resistance; Veins | 1964 |
MECHANISM OF TOLERANCE TO DIGITALIS AT LOW TEMPERATURES.
Topics: Biological Transport; Cell Membrane Permeability; Cold Temperature; Digitalis; Digitalis Glycosides; Dogs; Drug Tolerance; Hypothermia; Hypothermia, Induced; Ion Exchange; Myocardium; Ouabain; Potassium; Research; Sodium; Sodium, Dietary; Strophanthins; Temperature; Toxicology | 1964 |
DIRECT EFFECTS OF DIGITALIS ON RENAL BLOOD FLOW.
Topics: Animals; Blood Flow Velocity; Digitalis; Digitalis Glycosides; Dogs; Hexamethonium Compounds; Kidney; Kidneys, Artificial; Ouabain; Pharmacology; Renal Circulation; Research; Strophanthins; Sympathectomy; Vasomotor System | 1964 |
CENTRAL EMETIC ACTION AND TOXIC EFFECTS OF DIGITALIS IN CATS.
Topics: Carotid Arteries; Cats; Cerebral Ventricles; Cisterna Magna; Digitalis; Digitalis Glycosides; Emetics; Injections; Injections, Intra-Arterial; Injections, Intra-Articular; Injections, Intravenous; Injections, Spinal; Ouabain; Pharmacology; Portal System; Research; Strophanthins; Toxicology | 1965 |
INFLUENCE OF RESERPINE ON ARRHYTHMIAS, INOTROPIC EFFECTS, AND MYOCARDIAL POTASSIUM BALANCE INDUCED BY DIGITALIS MATERIALS.
Topics: Alkaloids; Arrhythmias, Cardiac; Digitalis; Dogs; Electrocardiography; Muscle Contraction; Myocardium; Ouabain; Pharmacology; Potassium; Rauwolfia; Research; Reserpine; Strophanthins; Toxicology; Tyramine | 1965 |
[Effect of ouabain and digoxin on the excitability of the papillary muscle of cats].
Topics: Animals; Cats; Digitalis; Digitalis Glycosides; Digoxin; Heart; Ouabain; Papillary Muscles; Plant Extracts; Psychomotor Agitation; Strophanthins | 1962 |
The 59th Symposium of the Society of General Physiologists. Na,K-ATPase and related cation pumps: structures, mechanisms, and diseases.
Topics: Animals; Binding Sites; Calcium-Binding Proteins; Cation Transport Proteins; Digitalis; Hepatolenticular Degeneration; Humans; Ion Transport; Menkes Kinky Hair Syndrome; Muscle Proteins; Ouabain; Protein Structure, Tertiary; Proteolipids; Receptors, G-Protein-Coupled; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2006 |
Digitalis glycosides, ouabain and strophanthin in general practice.
Topics: Digitalis; Digitalis Glycosides; Family Practice; General Practice; Ouabain; Plant Extracts; Strophanthins; Strophanthus | 1948 |
Effect of ouabain and digoxin on the energy-rich phosphate store of the heart.
Topics: Digitalis; Digitalis Glycosides; Digoxin; Heart; Humans; Ouabain; Phosphates | 1948 |
Digitalis-induced cell signaling by the sodium pump: on the relation of Src to Na(+)/K(+)-ATPase.
Topics: Animals; Digitalis; Enzyme Inhibitors; Oligomycins; Ouabain; Phosphorylation; Protein Subunits; Signal Transduction; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Swine; Vanadates | 2014 |