ouabain and beta-escin

ouabain has been researched along with beta-escin in 151 studies

Research

Studies (151)

Timeframe	Studies, this research(%)	All Research%
pre-1990	51 (33.77)	18.7374
1990's	61 (40.40)	18.2507
2000's	30 (19.87)	29.6817
2010's	9 (5.96)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, JQ; Rong, MZ; Xiong, C; Zeng, Q; Zhang, SZ; Zhang, YG	1
Doris, PA	1
Kelly, RA; Smith, TW	2
Bianchi, G; Ferrandi, M; Ferrari, P; Florio, M; Minotti, E; Salardi, S	1
Goto, A; Sugimoto, T; Yagi, N; Yamada, K; Yoshioka, M	1
Hamlyn, JM; Manunta, P	1
Gati, I; Haver, E; Katz, U; Lichtstein, D	1
Clark, MA; DuCharme, DW; Hamlyn, JM; Harris, DW; Ludens, JH; Lutzke, BS; Mandel, F; Mathews, WR; Sutter, DM	1
Clark, MA; DuCharme, DW; Hamlyn, JM; Harris, DW; Ludens, JH; Mandel, F; Mathews, WR	1
Fedorova, OV; Maslova, MN; Roukoyatkina, NI; Ukhanova, MV; Zhabko, EP	1
Clerico, A; Del Chicca, MG; Graziadei, L; Panarace, G; Pedrinelli, R; Salvetti, A; Spessot, M; Taddei, S	1
Blaustein, MP; Hamlyn, JM	1
Goto, A; Hui, C; Sugimoto, T; Yagi, N; Yamada, K	1
Masugi, F; Terano, Y; Tomii, A	1
Balzan, S; Biver, P; Ghione, S; Montali, U	1
Lamb, GD; Stephenson, DG	1
Goto, A; Sugimoto, T; Yamada, K	1
Goto, A; Hui, C; Sugimoto, T; Terano, Y; Yagi, N; Yamada, K	1
Agbanyo, M; Khatter, JC; Navaratnam, S	1
Babila, T; Gati, I; Haver, E; Katz, U; Lichtstein, D	1
Balzan, S; Biver, P; Gazzetti, P; Ghione, S; Montali, U	1
Goto, A; Ishii, M; Sugimoto, T; Yamada, K; Yoshioka, M	1
Devynck, MA; Le Quan Sang, KH; Meyer, P; Pernollet, MG	1
Brent, D; Gault, MH; Johnson, R; Longerich, L	1
Orlov, SN; Panyushkina, EA; Petrunyaka, VV; Severina, EP	1
Kitasato, H; Omatsu-Kanbe, M	1
Eguchi, C; Goto, A; Ishiguro, T; Ishii, M; Shimora, M; Sugimoto, T; Yamada, K; Yoshioka, M	1
Goto, A; Hui, C; Sugimoto, T; Yamada, K	1
de Mendonça, M; Devynck, MA; Grichois, ML; Meyer, P; Pernollet, MG; Wauquier, I	1
Karaki, H; Nagase, H; Ozaki, H; Urakawa, N	1
Humphries, KH; Nowaczynski, W; Pudek, MR; Seccombe, DW	1
Hirano, T; Hosaka, K; Mitsuhashi, H; Naitoh, T; Oka, K	1
Eguchi, C; Goto, A; Ishiguro, T; Ishii, M; Sugimoto, T; Yamada, K; Yoshioka, M	4
Balzan, S; Biver, P; Fantoni, M; Genovesi-Ebert, A; Ghione, S; Montali, U	1
Capra, C; Degan, M; Delva, P; Fallo, F; Lechi, A; Lechi, C; Mantero, F; Menegazzi, M; Steele, A	1
Bagrov, AIa; Maslova, MN; Rukoiatkina, NI; Ukhanova, MV; Zhabko, EP	1
Hallaq, HA; Haupert, GT	1
Ikeda, M; Morise, T; Okamoto, S; Takeda, R	2
Ciarimboli, G; Clerico, A; Cocci, F; Paci, A; Piras, F	1
Doris, PA; Stocco, DM	1
Alberts, D; Doris, PA; Durham, D; Kilgore, MW; Stocco, DM	1
Cloix, JF	1
Baczynskyj, L; Hamlyn, JM; Schenden, JA; Zyren, J	1
Kelly, RA	1
Overbeck, HW	1
Cloix, JF; Crabos, M; Grichois, ML; Meyer, P	1
Ibata, Y; Ijichi, H; Ikegaki, I; Matsuzawa, M; Murakami, S; Okabayashi, H; Okamura, H; Suga, K; Takahashi, H; Yoshimura, M	1
Bruening, RC; Butler, VP; Derguini, F; Kieval, RS; Rosen, MR	1
Buckalew, VM; Rauch, AL	1
Goto, A; Ishiguro, T; Ishii, M; Sugimoto, T; Yamada, K; Yoshioka, M	1
Ebara, H; Kuroume, T; Maruyama, K; Shimabukuro, N; Tomizawa, S	1
Cloix, JF; Devynck, MA; Grichois, ML; Guicheney, P; Meyer, P; Pernollet, MG	1
De Mendonca, M; Devynck, MA; Garay, R; Grichois, ML; Meyer, P; Pernollet, MG; Thorman, B	1
Barrowman, JA; Gault, MH; Ittel, TH; Johnson, E; Longerich, LL; Vasdev, SC	1
Cloix, JF; Crabos, M; Meyer, P	1
Agbanyo, M; Hoeschen, RJ; Khatter, JC	1
Durante, B; Lintlop, SP; Sen, AK; Sunahara, FA	1
Chanson, P; Deray, G; Devynck, MA; Luton, JP; Meyer, P; Pernollet, MG; Rieu, M	1
Cloix, JF; Crabos, M; Grichois, ML; Guicheney, P; Wainer, IW	1
Moreth, K; Renner, D; Schoner, W	1
Gault, MH; Johnson, E; Longerich, L; Prabhakaran, VM; Vasdev, S	1
Castańeda-Hernández, G	1
Cloix, JF; Crabos, M; Grichois, ML; Guicheney, P; Meyer, P	1
Hunt, SC; Stults, BM; Williams, RR; Wu, LL	1
Chiba, S; Katsuyama, Y; Tada, A; Tsukada, M; Zenda, H	1
Enomoto, Y; Ito, K; Kawagoe, Y; Morio, Y; Yamasaki, Y	1
Balzan, S; Clerico, A; Ghione, S; Montali, U	1
Donaldson, SK	1
Ellory, JC; O'Donnell, JM	1
Chau-Wong, M; Moyyen, S; Seeman, P	1
Chatterjee, ML; Roy, AR	1
Buckalew, VM; Gruber, KA; Hennessy, JF	1
Mircevová, L	1
Ermias, A; Foussard-Guilbert, F; Girault, M; Jallet, P; Laget, P; Tanguy, G	1
Mahler, HR; Sorensen, RG	1
Bäcker, A; Kramer, HJ; Meyer-Lehnert, H; Michel, H; Wanning, C	1
Clark, MA; Hamlyn, JM; Kolbasa, KP; Ludens, JH	1
Goto, A; Hui, C; Nagoshi, H; Sasabe, M; Yagi, N; Yamada, K; Yoshioka, M	1
Dawnay, AB; Hinson, JP; Raven, PW	1
Hansen, O	2
Graves, SW; Hollenberg, NK; Soszynski, PA; Tao, QF	1
Bates, RB; Dolata, DP; Gangwar, S; Gnabre, JN; Pinnas, JL	1
McDougall, JG; Yates, NA	2
Bagrov, AY; Fedorova, OV; Pinaev, AG; Roukoyatkina, NI; Ukhanova, MV	1
Berson, D; Deutsch, J; Gati, I; Landau, L; Lichtstein, D; Rozenman, Y; Samuelov, S	1
Biver, P; Ciarimboli, G; Paci, A	1
Anderson, DE; Bagrov, AY; Dmitrieva, RI; Fedorova, OV; French, AW	1
Ebus, JP; Stienen, GJ	1
Berova, N; Haupert, GT; Lo, LC; Ludens, JH; Nakanishi, K; Tymiak, AA; Warrack, B; Zhao, N	1
Graves, SW; Hollenberg, NK; Price, DA; Tao, QF	1
Balzan, S; Di Bartolo, V; Ghione, S; Montali, U	1
Hara, K; Kimura, Y; Komiyama, Y; Masuda, M; Mori, T; Munakata, M; Murakami, T; Nishimura, N; Okuda, K; Takahashi, H	1
De Angelis, C; Ferri, C; Piccoli, A; Riscazzi, M; Salvini, R; Santucci, A	1
Balzan, S; Bianchi, G; Ferrandi, M; Ferrari, P; Hamlyn, JM; Manunta, P	1
Balzan, S; Ghione, S; Montali, U	1
Del Bene, P; Paci, A; Sakakibara, M; Uchida, AO	1
Ensign, A; Graves, SW; Hollenberg, NK; Soszynski, P	1
Hamilton, BP; Hamlyn, JM; Laredo, J; Shah, JR	1
Bernini, G; Moretti, A; Paci, A; Salvetti, A; Sgrò, M	1
Douglas, PB; Weil, JR; Wheatly, MG	1
Fukuo, K; Hirotani, A; Kitano, S; Morimoto, S; Nakahashi, T; Nishibe, A; Ogihara, T; Yasuda, O	1
Chin, YW; Hsu, CC; Lee, JS; Liao, CP; Lin, MH; Wei, JS	1
Aminin, DL; Gorshkov, BA; Gorshkova, IA; Kapustina, II; Kicha, AA	1
Balzan, S; Ghione, S; Laricchia-Robbio, L; Montali, U; Revoltella, RP	1
Graves, SW; Hollenberg, NK; Tao, QF	1
Marín, J; Redondo, J	1
Bäcker, A; Kramer, HJ; Meyer-Lehnert, H	1
Arnon, A; Blaustein, MP; Hamlyn, JM	1
Goto, A; Yamada, K	1
Dong, XH; Hirose, S; Komiyama, Y; Kosaka, C; Masaki, H; Masuda, M; Nishimura, N; Takahashi, H	1
Alfazema, L; Dawnay, A; Harwood, S; Perrett, D	1
Bundgaard, H; Kjeldsen, K; Schmidt, TA	1
Butt, AN; Gillingwater, SD; Shepherd, PS; Swaminathan, R; Tennant, BP	1
Carper, DA; Lichtstein, D; McGowan, MH; Russell, P	1
Hamilton, BP; Hamlyn, JM; Kimura, K; Manunta, P	1
Bagrov, AY; Fedorova, OV; Lakatta, EG	1
Graves, SW; Hollenberg, NK; Markides, KE	1
Hirose, S; Komiyama, Y; Kosaka, C; Masuda, M; Mori, T; Munakata, M; Nishimura, N; Nishino, N; Okuda, K; Takahashi, H	1
Clark, BJ; el-Masri, MA; Qazzaz, HM; Valdes, R	1
Allen, DA; Harwood, SM; Raftery, MJ; Yaqoob, MM	1
Elmatzoglou, I; Sophocleous, A; Souvatzoglou, A	1
Huang, BS; Leenen, FH; Van Vliet, BN	1
Bauer, N; Grünbaum, EG; Hambarchian, N; Kirch, U; Krämer, U; Müller-Ehmsen, J; Neu, H; Schoner, W; Schwinger, RH; Zobel, C	1
Liu, J	1
Bagrov, AY; Bagrov, YY; Egorova, IA; Fedorova, OV; Manusova, NB	1
Buckalew, VM	2
Hilton, PJ; McKinnon, W	1
Komiyama, Y; Takahashi, H	1
Crespo, F; Fernandez-Botran, R; Ihenetu, K; Qazzaz, HM; Valdes, R	1
Haddy, FJ	1
Epstein, FH	1
Al-Ghoul, M; Valdes, R	1
Hilton, PJ; Lewis, LK; Lord, G; McKinnon, W; Nicholls, MG; Yandle, TG	1
Bianchi, G; Ferrandi, M; Hamlyn, JM; Manunta, P	1
Scheiner-Bobis, G; Schoner, W	1
Gao, XM; Hu, LM; Jiang, M; Liu, H; Liu, Y; Wang, XY; Zhang, BL; Zhang, H	1
Frampton, CM; Gravett, EC; Hilton, PJ; Lord, G; McKinnon, W; Nicholls, MG; Peron, JM	1
Baba, A; Furutani, K; Kamimura, D; Komiyama, Y; Komuro, I; Mano, T; Matsuda, T; Miwa, T; Ohtani, T; Omori, Y; Sakata, Y; Takahashi, H; Takeda, Y; Tamaki, S; Tsukamoto, Y; Umemura, S; Yamamoto, K; Yoshika, M	1
Dostanic, I; Hou, X; Lingrel, JB; Van Huysse, JW; Wu, H	1
Golovina, VA; Hamlyn, JM; Jacobs, BE; Liu, Y; Pulina, MV	1
Brandão, Md; Cardoso, FM; Caruso-Neves, C; Cassali, GD; de Souza, AM; Diniz, LR; dos Reis, AM; Portella, VG; Vieira, MA	1
Antos, LK; Blaustein, MP; Golovina, VA; Linde, CI	1
Chang, HS; Chang, WL; Chen, IS; Guh, JH; Hsu, JL; Hsu, LC; Kung, FL; Leu, WJ; Liu, FL; Yu, CC	1

Reviews

18 review(s) available for ouabain and beta-escin

Article	Year
Physiology and pharmacology of endogenous digitalis-like factors. Pharmacological reviews, 1992, Volume: 44, Issue:3 Topics: Animals; Binding Sites; Blood Proteins; Cardenolides; Digoxin; Humans; Lipids; Ouabain; Peptides; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids	1992
Ouabain, digitalis-like factors and hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1992, Volume: 10, Issue:7 Topics: Animals; Blood Pressure; Blood Proteins; Cardenolides; Digitalis Glycosides; Digoxin; Humans; Hypertension; Ion Transport; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1992
Digoxin-like immunoreactivity: is it still worth measuring? Life sciences, 1991, Volume: 49, Issue:23 Topics: Animals; Blood Proteins; Cardenolides; Cross Reactions; Digoxin; Humans; Hypertension; Kidney Diseases; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase	1991
[The role of an endogenous digoxin-like factor in regulating blood circulation and in the origin of arrhythmia in myocardial ischemia]. Terapevticheskii arkhiv, 1989, Volume: 61, Issue:7 Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Blood Circulation; Blood Proteins; Cardenolides; Coronary Disease; Digoxin; Female; Humans; Male; Middle Aged; Ouabain; Rats; Rats, Inbred Strains; Saponins; Sodium-Potassium-Exchanging ATPase	1989
Endogenous cardiac glycosidelike compounds. Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:5 Pt 2 Topics: Animals; Binding Sites; Blood Proteins; Blood Volume; Brain; Cardenolides; Digoxin; Humans; Hypertension; Lipids; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids; Vertebrates	1987
Endogenous cardiac glycosides. Advances in pharmacology (San Diego, Calif.), 1994, Volume: 25 Topics: Animals; Blood Proteins; Cardenolides; Cardiac Glycosides; Digoxin; Humans; Natriuretic Agents; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1994
Search for an endogenous mammalian cardiotonic factor. Advances in experimental medicine and biology, 1996, Volume: 404 Topics: Animals; Biological Factors; Cardenolides; Cardiotonic Agents; Digoxin; Humans; Ouabain; Plants, Medicinal; Saponins	1996
Vascular sodium pump: endothelial modulation and alterations in some pathological processes and aging. Pharmacology & therapeutics, 1999, Volume: 84, Issue:3 Topics: Aging; Animals; Blood Vessels; Cardenolides; Diabetes Mellitus; Digoxin; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Norepinephrine; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Vasodilation	1999
Putative roles of ouabainlike compound in hypertension: revisited. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Animals; Cardenolides; Digoxin; Humans; Hypertension; Ouabain; Saponins	2000
No evidence for a role in signal-transduction of Na+/K+-ATPase interaction with putative endogenous ouabain. European journal of biochemistry, 2003, Volume: 270, Issue:9 Topics: Animals; Calcium; Cardenolides; Digoxin; Enzyme Inhibitors; Isoenzymes; Ouabain; Protein Subunits; Saponins; Signal Transduction; Sodium-Potassium-Exchanging ATPase	2003
Ouabain-induced endocytosis and signal transduction of the Na/K-ATPase. Frontiers in bioscience : a journal and virtual library, 2005, Sep-01, Volume: 10 Topics: Animals; Cardenolides; Endocytosis; Kidney; LLC-PK1 Cells; Ouabain; Saponins; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Swine	2005
Endogenous digitalis-like factors. An historical overview. Frontiers in bioscience : a journal and virtual library, 2005, Sep-01, Volume: 10 Topics: Animals; Cardenolides; Digitalis Glycosides; Digoxin; History, 21st Century; Humans; Hypertension; Natriuretic Agents; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	2005
[Endogenous digitalis-like factor]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5 Topics: Animals; Bufanolides; Cardenolides; Epithelial Sodium Channels; Humans; Hypertension; Kidney Tubules; Natriuretic Agents; Ouabain; Saponins; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Vascular Resistance	2006
Mammalian cardenolides in cancer prevention and therapeutics. Therapeutic drug monitoring, 2008, Volume: 30, Issue:2 Topics: Adrenal Glands; Animals; Anticarcinogenic Agents; Apoptosis; Cardenolides; Cell Proliferation; Digoxin; Humans; Neoplasms; Ouabain; Saponins	2008
Ouabain, a circulating hormone secreted by the adrenals, is pivotal in cardiovascular disease. Fact or fantasy? Journal of hypertension, 2009, Volume: 27, Issue:1 Topics: Adrenal Glands; Animals; Cardenolides; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Humans; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	2009
Endogenous ouabain in cardiovascular function and disease. Journal of hypertension, 2009, Volume: 27, Issue:1 Topics: Adrenal Cortex; Animals; Body Fluids; Cardenolides; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Chromatography, High Pressure Liquid; Diet; Humans; Ouabain; Radioimmunoassay; Saponins	2009
[Endogenous cardioactive steroids--a new class of steroid hormones]. Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:13 Topics: Amphibians; Animals; Atrial Natriuretic Factor; Bufanolides; Cardenolides; Hormones; Humans; Hypertension; Mammals; Ouabain; Plant Growth Regulators; Saponins; Sodium Chloride, Dietary; Steroids	2009
Role of endogenous digitalis-like factors in the clinical manifestations of severe preeclampsia: a sytematic review. Clinical science (London, England : 1979), 2018, 06-29, Volume: 132, Issue:12 Topics: Birth Weight; Blood Pressure; Cardenolides; Female; Fetal Blood; Gestational Age; Humans; Infant, Newborn; Ouabain; Placenta; Pre-Eclampsia; Pregnancy; Saponins	2018

Trials

2 trial(s) available for ouabain and beta-escin

Article	Year
Detection of digitalis compounds using a surface plasmon resonance-based biosensor. Biosensors & bioelectronics, 1998, Nov-01, Volume: 13, Issue:10 Topics: Antibodies; Cardenolides; Digoxin; Enzyme Inhibitors; Humans; Infant, Newborn; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase; Surface Plasmon Resonance	1998
Circulating endogenous digitalis-like factor(s) (EDLF) in man is derived from the adrenals and its secretion is ACTH-dependent. Journal of endocrinological investigation, 2003, Volume: 26, Issue:7 Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Binding Sites; Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Digoxin; Erythrocytes; Female; Humans; Kinetics; Male; Middle Aged; Ouabain; Radioimmunoassay; Rubidium Radioisotopes; Saponins; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical	2003

Article

Year

Detection of digitalis compounds using a surface plasmon resonance-based biosensor.

Biosensors & bioelectronics, 1998, Nov-01, Volume: 13, Issue:10

Topics: Antibodies; Cardenolides; Digoxin; Enzyme Inhibitors; Humans; Infant, Newborn; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase; Surface Plasmon Resonance

1998

Circulating endogenous digitalis-like factor(s) (EDLF) in man is derived from the adrenals and its secretion is ACTH-dependent.

Journal of endocrinological investigation, 2003, Volume: 26, Issue:7

Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Binding Sites; Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Digoxin; Erythrocytes; Female; Humans; Kinetics; Male; Middle Aged; Ouabain; Radioimmunoassay; Rubidium Radioisotopes; Saponins; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical

2003

Other Studies

131 other study(ies) available for ouabain and beta-escin

Article	Year
[Effects of Panax notoginseng saponins on monophasic action potentials of heart and automaticity and contractility of isolated atria]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:6 Topics: Action Potentials; Animals; Drugs, Chinese Herbal; Female; Ginsenosides; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Rabbits; Saponins	1992
Characterization and scatchard binding analysis of adrenal digitalis-like material. Life sciences, 1992, Volume: 50, Issue:25 Topics: Adrenal Cortex; Animals; Binding, Competitive; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Erythrocytes; Humans; Mice; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured	1992
Is ouabain the endogenous digitalis? Circulation, 1992, Volume: 86, Issue:2 Topics: Animals; Blood Proteins; Cardenolides; Cell Communication; Digoxin; Homeostasis; Humans; Ouabain; Saponins; Signal Transduction; Sodium-Potassium-Exchanging ATPase	1992
Ouabainlike factor in Milan hypertensive rats. The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 2 Topics: Adrenal Glands; Animals; Brain; Cardenolides; Cattle; Digoxin; Erythrocytes; Hypertension; Hypothalamus; Kidney; Male; Ouabain; Potassium; Rats; Rats, Inbred Strains; Reference Values; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase	1992
Digitalis-like compounds in the toad Bufo viridis: tissue and plasma levels and significance in osmotic stress. Life sciences, 1992, Volume: 51, Issue:2 Topics: Animals; Blood Proteins; Brain; Bufonidae; Cardenolides; Digoxin; Osmolar Concentration; Ouabain; Saponins; Skin; Urea	1992
Purification of an endogenous digitalislike factor from human plasma for structural analysis. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 2 Topics: Antibodies; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Cross Reactions; Digoxin; Humans; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Spectrometry, Mass, Fast Atom Bombardment	1991
Mass spectral characterization of an endogenous digitalislike factor from human plasma. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 2 Topics: Acetylation; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Humans; Mass Spectrometry; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Spectrometry, Mass, Fast Atom Bombardment	1991
Endogenous plasma Na,K-ATPase inhibitory activity and digoxin like immunoreactivity after acute myocardial infarction. Cardiovascular research, 1991, Volume: 25, Issue:5 Topics: Adult; Aged; Angina, Unstable; Blood Proteins; Cardenolides; Digoxin; Erythrocytes; Female; Fluoroimmunoassay; Humans; Male; Middle Aged; Myocardial Infarction; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1991
Does a digoxin-like substance participate in vascular and pressure control during dietary sodium changes in patients with primary aldosteronism? Journal of hypertension, 1991, Volume: 9, Issue:5 Topics: Aldosterone; Blood Pressure; Blood Proteins; Cardenolides; Digoxin; Electrolytes; Forearm; Hematocrit; Hemodynamics; Humans; Hydrocortisone; Hyperaldosteronism; Norepinephrine; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Vascular Resistance; Vasoconstriction	1991
[Endogenous ouabain--key to the genesis of hypertension?]. Deutsche medizinische Wochenschrift (1946), 1991, Nov-02, Volume: 116, Issue:44 Topics: Animals; Blood Pressure; Cardenolides; Digoxin; Humans; Hypertension; Ouabain; Plasma Volume; Saponins; Sodium-Potassium-Exchanging ATPase	1991
Production and characterization of antibodies to ouabain. Japanese journal of medical science & biology, 1991, Volume: 44, Issue:3 Topics: Animals; Antibodies, Monoclonal; Blood Proteins; Cardenolides; Clone Cells; Cross Reactions; Digoxin; Enzyme-Linked Immunosorbent Assay; Female; Mice; Mice, Inbred BALB C; Molecular Structure; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1991
Digoxin-binding antibodies reverse the effect of endogenous digitalis-like compounds on Na,K-ATPase in erythrocytes. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6 Topics: Antibodies; Blood Proteins; Cardenolides; Digoxin; Erythrocytes; Humans; Ouabain; Rubidium Radioisotopes; Saponins; Sodium-Potassium-Exchanging ATPase	1991
Calcium release in skinned muscle fibres of the toad by transverse tubule depolarization or by direct stimulation. The Journal of physiology, 1990, Volume: 423 Topics: Action Potentials; Animals; Bufo marinus; Calcium; Choline; In Vitro Techniques; Muscle Contraction; Muscles; Ouabain; Potassium; Ruthenium Red; Saponins; Sarcoplasmic Reticulum; Sodium	1990
Effect of endogenous digitalis-like factor on endothelin secretion from bovine endothelial cells. Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 7 Topics: Animals; Cardenolides; Cattle; Cells, Cultured; Digoxin; Endothelins; Endothelium, Vascular; Erythrocytes; Humans; In Vitro Techniques; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase	1991
Ouabain as endogenous digitalis-like factor in animals? Clinical chemistry, 1992, Volume: 38, Issue:1 Topics: Animals; Blood Proteins; Cardenolides; Digoxin; Humans; Immunoglobulin G; Ouabain; Saponins	1992
Endogenous inotropic substance from heart tissue has digitalis-like properties. Life sciences, 1991, Volume: 48, Issue:5 Topics: Animals; Antibodies; Biological Transport; Blood Proteins; Cardenolides; Cardiotonic Agents; Chromatography, Liquid; Cross Reactions; Digitalis Glycosides; Digoxin; Dogs; Kidney; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Saponins; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Swine	1991
Effect of salt acclimation on digitalis-like compounds in the toad. Biochimica et biophysica acta, 1991, Jan-23, Volume: 1073, Issue:1 Topics: Animals; Blood Proteins; Brain; Bufonidae; Cardenolides; Digoxin; Female; Homeostasis; Male; Ouabain; Salts; Saponins; Skin; Sodium Chloride; Water-Electrolyte Balance	1991
Partial purification of endogenous digitalis-like compound(s) in cord blood. Clinical chemistry, 1991, Volume: 37, Issue:2 Topics: Adult; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Cross Reactions; Digitalis; Digoxin; Fetal Blood; Humans; Infant, Newborn; Ouabain; Plants, Medicinal; Plants, Toxic; Radioimmunoassay; Rubidium Radioisotopes; Saponins	1991
Immunoreactivity of endogenous digitalis-like factors. Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8 Topics: Antigen-Antibody Reactions; Binding, Competitive; Blood Proteins; Bufanolides; Cardenolides; Cross Reactions; Digoxin; Humans; In Vitro Techniques; Ouabain; Saponins	1991
Plasma digitalis-like activity and cytosolic Ca2+ in essential hypertension. American journal of hypertension, 1990, Volume: 3, Issue:3 Topics: Adolescent; Adult; Aged; Blood Platelets; Blood Proteins; Calcium; Cardenolides; Cytosol; Digoxin; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1990
Plasma conjugated androgens in a dialysis-dependent male as immunoreactive digitalis-like factors. Clinical nephrology, 1990, Volume: 34, Issue:2 Topics: Adult; Androgens; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Hemodialysis, Home; Humans; Kidney Failure, Chronic; Male; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Spectrometry, Mass, Fast Atom Bombardment	1990
The ATPase activity of saponin-treated rat erythrocytes: regulation by monovalent cations, calcium, ouabain, and furosemide. Biochimica et biophysica acta, 1990, Dec-14, Volume: 1030, Issue:2 Topics: Adenosine Triphosphatases; Animals; Buffers; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Calmodulin; Cations, Monovalent; Cell Membrane Permeability; Dose-Response Relationship, Drug; Epithelium; Furosemide; Imidazoles; Kidney; Kinetics; Male; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase	1990
Insulin stimulates the translocation of Na+/K(+)-dependent ATPase molecules from intracellular stores to the plasma membrane in frog skeletal muscle. The Biochemical journal, 1990, Dec-15, Volume: 272, Issue:3 Topics: Animals; Cell Membrane; Chromatography, Ion Exchange; Insulin; Kinetics; Microsomes; Muscles; Ouabain; Protein Binding; Rana catesbeiana; Saponins; Sodium-Potassium-Exchanging ATPase	1990
Isolation of a urinary digitalis-like factor indistinguishable from digoxin. Biochemical and biophysical research communications, 1990, Dec-31, Volume: 173, Issue:3 Topics: Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Digoxin; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Male; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Tritium	1990
Endogenous digitalis-like factor as a stimulator of endothelin secretion from endothelial cells. Biochemical and biophysical research communications, 1990, Oct-15, Volume: 172, Issue:1 Topics: Animals; Blood Proteins; Cardenolides; Cattle; Cells, Cultured; Digoxin; Endothelins; Endothelium, Vascular; Humans; Kinetics; Ouabain; Pulmonary Artery; Radioimmunoassay; Saponins	1990
[Compounds of the digoxin type in essential and experimental hypertension]. Archives des maladies du coeur et des vaisseaux, 1986, Volume: 79, Issue:6 Topics: Adenosine Triphosphatases; Animals; Antibody Specificity; Blood Proteins; Cardenolides; Digoxin; Erythrocyte Membrane; Female; Humans; Hypertension; Ion Channels; Kidney; Male; Ouabain; Rats; Rats, Inbred Strains; Saponins	1986
Effects of palytoxin on contractile response and calcium movement in guinea-pig taenia coli. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 86, Issue:2 Topics: Acrylamides; Adenosine Triphosphate; Animals; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Muscle Contraction; Ouabain; Potassium; Saponins; Sodium; Verapamil	1987
Digoxin-like immunoreactivity, displacement of ouabain and inhibition of Na+/K+ ATPase by four steroids known to be increased in essential hypertension. Clinical biochemistry, 1989, Volume: 22, Issue:1 Topics: Animals; Blood Proteins; Cardenolides; Digoxin; Dogs; Hypertension; Immune Sera; In Vitro Techniques; Kidney; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids	1989
Endogenous digoxin-like activity of mammalian-lignans and their derivatives. Research communications in chemical pathology and pharmacology, 1989, Volume: 64, Issue:2 Topics: Animals; Binding, Competitive; Blood Proteins; Butylene Glycols; Cardenolides; Cross Reactions; Digoxin; Dogs; Erythrocytes; Humans; In Vitro Techniques; Kidney; Lignans; Ouabain; Plant Extracts; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase	1989
Existence of a polar digitalis-like factor in mammalian hypothalamus. Biochemical and biophysical research communications, 1989, Jun-30, Volume: 161, Issue:3 Topics: Animals; Binding, Competitive; Blood Proteins; Cardenolides; Cattle; Chromatography, High Pressure Liquid; Digoxin; Dogs; Erythrocytes; Humans; Hypothalamus; Kidney; Kinetics; Ouabain; Rats; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase	1989
Comparison between endogenous digoxin-like immunoreactivity and 86Rb uptake by erythrocytes in extracts of human plasma. Clinical science (London, England : 1979), 1989, Volume: 77, Issue:4 Topics: Adult; Blood Proteins; Cardenolides; Digoxin; Erythrocytes; Humans; Hypertension; Infant, Newborn; Ouabain; Rubidium Radioisotopes; Saponins; Sodium Channels; Sodium-Potassium-Exchanging ATPase	1989
Plasma ouabain-like activity in essential hypertensive patients and in subjects with primary aldosteronism. Mineral and electrolyte metabolism, 1989, Volume: 15, Issue:5 Topics: Adolescent; Adult; Aged; Blood Pressure; Cardenolides; Digoxin; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Ouabain; Protein Binding; Renin; Saponins; Sodium-Potassium-Exchanging ATPase	1989
Positive inotropic effects of the endogenous Na+/K(+)-transporting ATPase inhibitor from the hypothalamus. Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:24 Topics: Animals; Benzofurans; Blood Proteins; Calcium; Cardenolides; Cattle; Cells, Cultured; Digoxin; Fluorescent Dyes; Fura-2; Heart; Heart Rate; Hypothalamus; Kinetics; Myocardial Contraction; Myocardium; Ouabain; Rats; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence	1989
Biochemical characterization of a digitalis-like substance in human urine, partially purified by high pressure liquid chromatography. Cardiology, 1989, Volume: 76, Issue:6 Topics: Animals; Binding, Competitive; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Cross Reactions; Digoxin; Female; Humans; Male; Myocardial Contraction; Ouabain; Radioimmunoassay; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical	1989
The possible role of endogenous digitalis-like substance in the regulation of circadian changes in urinary electrolyte excretion in man. Endocrinologia japonica, 1989, Volume: 36, Issue:6 Topics: Adult; Atrial Natriuretic Factor; Blood Proteins; Cardenolides; Circadian Rhythm; Digoxin; Humans; Male; Ouabain; Potassium; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase	1989
Specific binding of cardiac glycoside drugs and endogenous digitalis-like substances to particulate membrane fractions from human placenta. Clinical chemistry, 1989, Volume: 35, Issue:10 Topics: Binding Sites; Blood Proteins; Cardenolides; Cardiac Glycosides; Cortisone; Digoxin; Female; Furosemide; Humans; Norepinephrine; Ouabain; Placenta; Pregnancy; Progesterone; Propranolol; Radioligand Assay; Receptors, Drug; Saponins; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions	1989
An endogenous digitalis-like factor derived from the adrenal gland: studies of adrenal tissue from various sources. Endocrinology, 1989, Volume: 125, Issue:5 Topics: Adrenal Glands; Aminoglutethimide; Animals; Blood Proteins; Cardenolides; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Digoxin; Dogs; Erythrocyte Membrane; Ether; Female; Humans; Male; Ouabain; Radioimmunoassay; Rats; Rats, Inbred Strains; Saponins; Species Specificity	1989
An endogenous digitalis-factor derived from the adrenal gland: studies of adrenocortical tumor cells. Endocrinology, 1989, Volume: 125, Issue:5 Topics: Adrenal Cortex Neoplasms; Aminoglutethimide; Animals; Blood Proteins; Cardenolides; Cell Line; Digoxin; Erythrocyte Membrane; Humans; Kinetics; Mice; Ouabain; Pregnenolone; Radioimmunoassay; Saponins	1989
Endogenous digitalislike compounds. A tentative update of chemical and biological studies. Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:5 Pt 2 Topics: Animals; Blood Platelets; Blood Proteins; Cardenolides; Digoxin; Diuresis; Dogs; Drug Interactions; Erythrocytes; Fatty Acids; Humans; Mammals; Natriuresis; Ouabain; Peptides; Potassium; Ranidae; Rats; Saponins; Serotonin; Sodium-Potassium-Exchanging ATPase; Steroids; Urine	1987
Purification and characterization of digitalislike factors from human plasma. Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:5 Pt 2 Topics: 4-Nitrophenylphosphatase; Blood Proteins; Blood Volume; Cardenolides; Cardiac Glycosides; Chromatography, Liquid; Digoxin; Dose-Response Relationship, Drug; Humans; Isotonic Solutions; Lysophospholipids; Membrane Lipids; Norepinephrine; Ouabain; Potassium; Saponins; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vanadates	1987
The vascular Na+-K+ pump in experimental hypertension. Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:5 Pt 2 Topics: Animals; Arteries; Arterioles; Blood Proteins; Cardenolides; Desipramine; Digoxin; Hindlimb; Hypertension, Renovascular; Male; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Saponins; Sodium-Potassium-Exchanging ATPase	1987
An endogenous digitalis-like compound extracted from human urine: biochemical and chemical studies. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:8 Topics: Adult; Animals; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Erythrocytes; Female; Humans; Hypertension; Kidney; Kinetics; Male; Natriuresis; Ouabain; Rats; Rats, Inbred Strains; Reference Values; Saponins; Serotonin; Sodium-Potassium-Exchanging ATPase	1987
Evidence for a digitalis-like substance in the hypothalamopituitary axis in rats: implications in the central cardiovascular regulation associated with an excess intake of sodium. Japanese circulation journal, 1987, Volume: 51, Issue:10 Topics: Animals; Blood Pressure; Blood Proteins; Cardenolides; Cardiovascular System; Desoxycorticosterone; Digoxin; Heart Rate; Hypertension; Hypothalamo-Hypophyseal System; Immunohistochemistry; Injections, Intraventricular; Male; Ouabain; Pituitary-Adrenal System; Radioimmunoassay; Rats; Rats, Inbred Strains; Saponins; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary	1987
Cellular electrophysiologic effects of vertebrate digitalis-like substances. Journal of the American College of Cardiology, 1988, Volume: 11, Issue:3 Topics: Action Potentials; Animals; Bile; Blood Proteins; Bufanolides; Cardenolides; Digoxin; Dogs; Electrophysiology; Female; Heart Conduction System; Humans; Male; Membrane Potentials; Ouabain; Purkinje Fibers; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase	1988
Tissue distribution of an endogenous ligand to the Na, K ATPase molecule. Biochemical and biophysical research communications, 1988, Apr-29, Volume: 152, Issue:2 Topics: Animals; Binding, Competitive; Blood Proteins; Brain Chemistry; Cardenolides; Digoxin; Intracellular Fluid; Male; Ouabain; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Drug; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase; Tissue Distribution	1988
The effects of urinary digitalislike factor on cultured vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:6 Pt 2 Topics: Animals; Blood Proteins; Calcium; Cardenolides; Cells, Cultured; Digoxin; Erythrocyte Membrane; Humans; Lymphocytes; Male; Muscle, Smooth, Vascular; Ouabain; Rats; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase; Urine	1988
Demonstration of the presence of digoxin-like immunoreactive substance (DLIS) in the serum and urine in children with nephrotic syndrome. Clinical nephrology, 1988, Volume: 29, Issue:5 Topics: Blood Proteins; Cardenolides; Child; Digoxin; Female; Humans; Male; Natriuresis; Nephrotic Syndrome; Ouabain; Radioimmunoassay; Receptors, Drug; Saponins; Sodium-Potassium-Exchanging ATPase; Time Factors	1988
Purification and characterization of human urine-derived digitalis-like factor. Biochemical and biophysical research communications, 1988, Aug-15, Volume: 154, Issue:3 Topics: Animals; Blood Proteins; Brain; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Dogs; Erythrocytes; Humans; Kidney; Kinetics; Ouabain; Potassium; Rats; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase; Synaptosomes	1988
Platelet 5-HT content and uptake in essential hypertension: role of endogenous digitalis-like factors and plasma cholesterol. Journal of hypertension, 1988, Volume: 6, Issue:11 Topics: Adult; Blood Platelets; Blood Proteins; Cardenolides; Cholesterol; Digoxin; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Saponins; Serotonin; Sodium-Potassium-Exchanging ATPase	1988
Effects of human urine-derived digitalis-like factor on cultured renal tubular epithelial cells. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4 Topics: Animals; Binding, Competitive; Blood Proteins; Cardenolides; Cell Line; Chromatography, High Pressure Liquid; Digoxin; Dogs; Epithelium; Kidney Tubules; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Swine	1988
Hypotensive action of canrenone in a model of hypertension where ouabain-like factors are present. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1985, Volume: 3, Issue:3 Topics: Animals; Antihypertensive Agents; Blood Volume; Canrenone; Cardenolides; Digoxin; Erythrocytes; Hypertension, Renal; Male; Ouabain; Rats; Rats, Wistar; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase	1985
Bile salts as endogenous digitalis like factors. Clinical and investigative medicine. Medecine clinique et experimentale, 1986, Volume: 9, Issue:3 Topics: Acute Kidney Injury; Adult; Antibodies; Bile; Bile Acids and Salts; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Female; Humans; Liver Diseases; Male; Middle Aged; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase	1986
Recent progress on an endogenous digitalislike factor in hypertension. Journal of clinical hypertension, 1986, Volume: 2, Issue:2 Topics: Adult; Binding, Competitive; Blood Proteins; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Erythrocytes; Female; Homeostasis; Humans; Hypertension; Male; Middle Aged; Ouabain; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase	1986
Endogenous digitalis-like substance in pig left ventricle. Life sciences, 1986, Dec-22, Volume: 39, Issue:25 Topics: Animals; Binding, Competitive; Blood Proteins; Cardenolides; Digoxin; Heart Ventricles; Molecular Weight; Myocardial Contraction; Ouabain; Receptors, Adrenergic, beta; Saponins; Sodium-Potassium-Exchanging ATPase; Swine	1986
Digitalis-like biological activity in rat cerebellum. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1986, Volume: 64, Issue:10 Topics: Animals; Atrial Function; Blood Proteins; Cardenolides; Cerebellum; Digoxin; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Magnesium; Myocardial Contraction; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Synaptosomes	1986
Evidence of an endogenous digitalis-like factor in the plasma of patients with acromegaly. The New England journal of medicine, 1987, Mar-05, Volume: 316, Issue:10 Topics: Acromegaly; Adult; Blood Proteins; Cardenolides; Cells, Cultured; Digoxin; Erythrocytes; Female; Humans; Male; Middle Aged; Ouabain; Plasma Volume; Saponins; Sodium-Potassium-Exchanging ATPase	1987
Further biochemical characterization of an Na+ pump inhibitor purified from human urine. European journal of biochemistry, 1987, Jan-02, Volume: 162, Issue:1 Topics: Adenosine Triphosphatases; Animals; Binding Sites; Blood Platelets; Brain; Cardenolides; Catalysis; Digoxin; Dogs; Humans; Kidney; Ouabain; Rabbits; Saponins; Serotonin; Sodium-Potassium-Exchanging ATPase	1987
A quantitative receptor assay for "digitalis-like" compounds in serum. Demonstration of raised concentrations in essential hypertension and correlation with arterial blood pressure. Klinische Wochenschrift, 1987, Feb-16, Volume: 65, Issue:4 Topics: Adolescent; Adult; Binding, Competitive; Blood Pressure; Blood Proteins; Cardenolides; Digoxin; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Ouabain; Radioligand Assay; Receptors, Drug; Saponins; Sodium-Potassium-Exchanging ATPase	1987
Plasma endogenous digitalis-like factors in healthy individuals and in dialysis-dependent and kidney transplant patients. Clinical nephrology, 1987, Volume: 27, Issue:4 Topics: Adult; Blood Proteins; Cardenolides; Dehydroepiandrosterone; Digoxin; Female; Humans; Hydrocortisone; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Ouabain; Radioimmunoassay; Renal Dialysis; Saponins; Sodium-Potassium-Exchanging ATPase	1987
Presence of endogenous digitalis-like activity in mammalian heart not due to fatty acids. Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Blood Proteins; Cardenolides; Digoxin; Fatty Acids; Guinea Pigs; Kinetics; Linoleic Acid; Linoleic Acids; Myocardium; Oleic Acid; Oleic Acids; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1987
Endogenous Na+ transport inhibitor in human hypertension: further biochemical and chemical studies. Klinische Wochenschrift, 1987, Volume: 65 Suppl 8 Topics: Animals; Blood Platelets; Cardenolides; Chemical Phenomena; Chemistry; Digoxin; Dogs; Humans; Hypertension; Osmolar Concentration; Ouabain; Peptides; Potassium; Rats; Saponins; Serotonin; Sodium; Sodium-Potassium-Exchanging ATPase	1987
Presence of digitalis-like factor in mammalian plasma. Biochemical and biophysical research communications, 1988, Apr-15, Volume: 152, Issue:1 Topics: Binding, Competitive; Blood Proteins; Cardenolides; Digoxin; Erythrocytes; Humans; Kinetics; Ouabain; Receptors, Drug; Saponins; Sodium-Potassium-Exchanging ATPase	1988
A digoxin-like factor associates with erythrocyte sodium concentration, sodium transport, and ouabain binding. Clinical biochemistry, 1988, Volume: 21, Issue:3 Topics: Adult; Aging; Blood Pressure; Blood Proteins; Body Weight; Cardenolides; Child; Digoxin; Erythrocytes; Female; Humans; Hypertension; Male; Ouabain; Protein Binding; Radioimmunoassay; Saponins; Sodium	1988
Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients. Heart and vessels, 1987, Volume: 3, Issue:3 Topics: Animals; Arteries; Blood Proteins; Cardenolides; Digoxin; Dogs; Ear, External; Epinephrine; Humans; Hypertension; In Vitro Techniques; Mesenteric Arteries; Ouabain; Phentolamine; Potassium Chloride; Quinazolines; Saponins; Vasoconstrictor Agents; Verapamil	1987
Positive inotropic action of saponins on isolated atrial and papillary muscles from the guinea-pig. British journal of pharmacology, 1986, Volume: 88, Issue:1 Topics: Animals; Erythrocytes; Female; Guinea Pigs; Hemolysis; Holothurin; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Ouabain; Papillary Muscles; Rabbits; Saponins; Stimulation, Chemical	1986
Correlation between endogenous digoxin-like immunoreactivity and 3H-ouabain displacement on erythrocyte membranes in extracts of human plasma. Clinical biochemistry, 1986, Volume: 19, Issue:5 Topics: Adult; Blood Proteins; Cardenolides; Digoxin; Erythrocyte Membrane; Female; Humans; Infant, Newborn; Male; Ouabain; Pregnancy; Saponins	1986
Peeled mammalian skeletal muscle fibers. Possible stimulation of Ca2+ release via a transverse tubule-sarcoplasmic reticulum mechanism. The Journal of general physiology, 1985, Volume: 86, Issue:4 Topics: Animals; Caffeine; Calcium; Chlorides; Female; In Vitro Techniques; Isometric Contraction; Kinetics; Muscle Contraction; Muscles; Ouabain; Rabbits; Saponins; Sarcoplasmic Reticulum	1985
The binding of cardiac glycosides to bull spermatozoa. Experientia, 1970, Jan-15, Volume: 26, Issue:1 Topics: Adenosine Triphosphatases; Amides; Animals; Binding Sites; Biological Transport, Active; Cattle; Cell Membrane; Cyanides; Depression, Chemical; Digoxin; Enzyme Activation; Fluorides; Iodoacetates; Male; Ouabain; Saponins; Spermatozoa; Surface-Active Agents; Tritium	1970
The membrane binding of morphine, diphenylhydantoin, and tetrahydrocannabinol. Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:12 Topics: Adenosine Triphosphate; Animals; Brain; Cannabis; Carbon Isotopes; Cell Membrane; Dinitrophenols; Dronabinol; Erythrocytes; Guinea Pigs; Humans; In Vitro Techniques; Membranes; Morphine; Nerve Endings; Neural Conduction; Ouabain; Phenytoin; Saponins; Synaptic Vesicles; Synaptosomes; Temperature; Time Factors	1972
Pharmacological observations on saponins from Cestrum diurnum and Cestrum nocturnum. Indian journal of experimental biology, 1968, Volume: 6, Issue:3 Topics: Animals; Anura; Guinea Pigs; Muscles; Ouabain; Plants, Medicinal; Rats; Saponins	1968
Studies of a digitalis-like autacoid in dog plasma. Transactions of the American Clinical and Climatological Association, 1984, Volume: 95 Topics: Animals; Autacoids; Blood Proteins; Brain; Cardenolides; Digoxin; Dogs; Kidney; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase; Swine	1984
Does the conformation of Mg-ATPase (spectrin-dependent ATPase) influence the passive permeability to K+? Archives internationales de physiologie et de biochimie, 1980, Volume: 88, Issue:1 Topics: Adenosine Triphosphatases; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Cell Membrane Permeability; Erythrocytes; Humans; Lead; Membrane Proteins; Ouabain; Oxazines; Potassium; Protein Conformation; Saponins; Sodium; Spectrin	1980
Detergent effects of kinetic properties of (Na+ +K+)-ATPase from kidney membranes. Biochimica et biophysica acta, 1982, Nov-08, Volume: 692, Issue:2 Topics: Animals; Cell Membrane; Deoxycholic Acid; Detergents; Kidney Medulla; Kinetics; Ouabain; Phosphates; Phosphorylation; Potassium; Saponins; Sodium Dodecyl Sulfate; Sodium-Potassium-Exchanging ATPase; Surface-Active Agents	1982
Localization of endogenous ATPases at the nerve terminal. Journal of bioenergetics and biomembranes, 1982, Volume: 14, Issue:5-6 Topics: Adenosine Triphosphatases; Animals; Digitonin; In Vitro Techniques; Male; Nerve Endings; Ouabain; Rats; Rats, Inbred Strains; Saponins; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions; Synaptosomes	1982
Cellular mechanisms of action of a ouabain-like factor in vascular smooth-muscle cells. Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 2 Topics: Adult; Amiloride; Animals; Aorta; Arginine Vasopressin; Biological Factors; Calcium; Cardenolides; Cells, Cultured; Digoxin; Humans; Hydrogen-Ion Concentration; Male; Molecular Weight; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Sprague-Dawley; Saponins; Sodium-Potassium-Exchanging ATPase	1993
Digitalis-like factor and ouabain-like compound in plasma of volume-expanded dogs. Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 2 Topics: Animals; Blood Proteins; Blood Volume; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Dogs; Natriuresis; Ouabain; Saponins	1993
Digitalis-like factors from human urine. Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 2 Topics: Binding Sites; Biological Factors; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Digoxin; Erythrocytes; Humans; Immunoglobulin G; Magnetic Resonance Spectroscopy; Male; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1993
Why we should give a qualified welcome to ouabain: a whole new family of adrenal steroid hormones? The Journal of endocrinology, 1995, Volume: 146, Issue:3 Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Blood Proteins; Cardenolides; Cardiotonic Agents; Digoxin; Humans; Mammals; Ouabain; Plant Growth Regulators; Saponins; Sodium-Potassium-Exchanging ATPase	1995
Do putative endogenous digitalis-like factors have a physiological role? Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:5 Topics: Animals; Biological Factors; Blood Proteins; Cardenolides; Digoxin; Humans; Ouabain; Reference Values; Saponins; Sodium-Potassium-Exchanging ATPase	1994
Sensitive assay for sodium pump inhibition. Clinical chemistry, 1994, Volume: 40, Issue:8 Topics: Animals; Blood Proteins; Cardenolides; Cattle; Digoxin; Humans; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	1994
Tylophora compounds as Na+/K(+)-ATPase inhibitors. General pharmacology, 1993, Volume: 24, Issue:5 Topics: 4-Butyrolactone; Animals; Basement Membrane; Crystallography, X-Ray; In Vitro Techniques; Kidney Cortex; Models, Molecular; Molecular Conformation; Ouabain; Phenanthrenes; Plants; Rabbits; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids	1993
Effects of direct renal arterial infusion of bufalin and ouabain in conscious sheep. British journal of pharmacology, 1993, Volume: 108, Issue:3 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Proteins; Bufanolides; Cardenolides; Digoxin; Female; Heart Rate; Infusions, Intra-Arterial; Natriuresis; Ouabain; Potassium; Renal Artery; Renal Circulation; Saponins; Sheep; Sodium; Sodium-Potassium-Exchanging ATPase	1993
Digitalis-like and vasoconstrictor effects of endogenous digoxin-like factor(s) from the venom of Bufo marinus toad. European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3 Topics: Amphibian Venoms; Animals; Aorta, Abdominal; Blood Proteins; Bufanolides; Bufo marinus; Cardenolides; Digitalis Glycosides; Digoxin; Erythrocytes; Female; Fluorescent Antibody Technique; Immunoglobulin G; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Ouabain; Parotid Gland; Rats; Rats, Wistar; Saponins; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Vasoconstriction	1993
Identification of digitalis-like compounds in human cataractous lenses. European journal of biochemistry, 1993, Aug-15, Volume: 216, Issue:1 Topics: Animals; Antibodies; Blood Proteins; Bufanolides; Cardenolides; Cataract; Digitalis; Digoxin; Humans; Lens Nucleus, Crystalline; Mass Spectrometry; Microsomes; Molecular Weight; Ouabain; Plants, Medicinal; Plants, Toxic; Rats; Saponins; Sodium-Potassium-Exchanging ATPase	1993
Human placenta radioreceptor assay with digoxin and ouabain to detect endogenous digitalis-like factor(s) in human plasma and urine. Clinical chemistry, 1996, Volume: 42, Issue:2 Topics: Acetonitriles; Adult; Binding, Competitive; Blood Proteins; Cardenolides; Cell Membrane; Digoxin; Female; Humans; Infant, Newborn; Iodine Radioisotopes; Male; Methanol; Middle Aged; Ouabain; Placenta; Pregnancy; Radioligand Assay; Reference Values; Saponins; Sensitivity and Specificity	1996
Plasma marinobufagenin-like and ouabain-like immunoreactivity during saline volume expansion in anesthetized dogs. Cardiovascular research, 1996, Volume: 31, Issue:2 Topics: Animals; Autoantibodies; Bufanolides; Bufo marinus; Cardenolides; Digoxin; Dogs; Fluid Shifts; Immune Sera; Male; Ouabain; Plasma Volume; Saponins; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	1996
Origin of concurrent ATPase activities in skinned cardiac trabeculae from rat. The Journal of physiology, 1996, May-01, Volume: 492 ( Pt 3) Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Enzyme Inhibitors; In Vitro Techniques; Indoles; Isometric Contraction; Male; Myocardium; NAD; Octoxynol; Ouabain; Rats; Rats, Inbred Strains; Saponins; Sarcoplasmic Reticulum	1996
Interaction of exogenous ouabain and chronic mineralocorticoid treatment in the kidney of the conscious sheep. Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1 Topics: Aldosterone; Animals; Cardenolides; Digoxin; Drug Synergism; Female; Infusions, Intra-Arterial; Kidney; Ouabain; Renal Artery; Saponins; Sheep; Sodium	1997
Sodium pump isoform specificity for the digitalis-like factor isolated from human peritoneal dialysate. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:3 Topics: Animals; Blotting, Western; Brain; Cardenolides; Digoxin; Enzyme Inhibitors; Female; Humans; Kidney; Microsomes; Muscles; Ouabain; Peritoneal Dialysis; Pregnancy; Rats; Rats, Sprague-Dawley; Saponins; Sodium-Potassium-Exchanging ATPase	1997
Further evidence for an endogenous digitalis-like compound in newborn and adult plasma detected by anti-ouabain antiserum. Life sciences, 1997, Volume: 60, Issue:12 Topics: Adult; Cardenolides; Cross Reactions; Digoxin; Humans; Infant, Newborn; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase	1997
Vasodepressor effects of exercise are accompanied by reduced circulating ouabainlike immunoreactivity and normalization of nitric oxide synthesis. Clinical and experimental hypertension (New York, N.Y. : 1993), 1997, Volume: 19, Issue:3 Topics: Adult; Aged; Blood Pressure; Cardenolides; Chromatography, High Pressure Liquid; Diabetes Mellitus; Digoxin; Enzyme-Linked Immunosorbent Assay; Exercise; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Obesity; Ouabain; Saponins	1997
Isolation and characterization of a digoxin-like immunoreactive substance from human urine by affinity chromatography. Clinical chemistry, 1997, Volume: 43, Issue:8 Pt 1 Topics: Animals; Antibodies; Binding, Competitive; Cardenolides; Cats; Chromatography, Affinity; Chromatography, High Pressure Liquid; Digoxin; Dogs; Enzyme Inhibitors; Erythrocytes; Humans; Kidney; Male; Ouabain; Radioimmunoassay; Rubidium Radioisotopes; Saponins; Sodium-Potassium-Exchanging ATPase	1997
Ouabain-like factor quantification in mammalian tissues and plasma: comparison of two independent assays. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:4 Topics: Adrenal Glands; Animals; Biological Factors; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Dogs; Enzyme Inhibitors; Humans; Hypothalamus; Immune Sera; Male; Methods; Osmolar Concentration; Ouabain; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Saponins; Sodium-Potassium-Exchanging ATPase; Tissue Extracts	1997
Evidence of an endogenous ouabain-like immunoreactive compound with digitalis-like properties in the human. Annals of the New York Academy of Sciences, 1997, Nov-03, Volume: 834 Topics: Biological Factors; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Enzyme Inhibitors; Erythrocytes; Humans; Infant, Newborn; Ouabain; Radioimmunoassay; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase	1997
Synthetic candidates for EDLF. Activity on human placenta digitalis receptors. Annals of the New York Academy of Sciences, 1997, Nov-03, Volume: 834 Topics: Cardenolides; Cell Membrane; Digitoxin; Digoxin; Enzyme Inhibitors; Estradiol Congeners; Female; Humans; Iodine Radioisotopes; Kinetics; Ouabain; Placenta; Pregnancy; Radioligand Assay; Saponins; Sodium-Potassium-Exchanging ATPase; Tritium	1997
Specificity of the vascular smooth muscle contractile response to a labile digitalis-like factor in peritoneal dialysate: the influence of potassium. American journal of hypertension, 1997, Volume: 10, Issue:12 Pt 1 Topics: Animals; Cardenolides; Cattle; Digoxin; In Vitro Techniques; Muscle, Smooth, Vascular; Ouabain; Potassium; Saponins; Serotonin; Vasoconstriction	1997
Different signaling pathways mediate stimulated secretions of endogenous ouabain and aldosterone from bovine adrenocortical cells. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Factors; Bucladesine; Cardenolides; Cattle; Cells, Cultured; Digoxin; Enzyme Inhibitors; Imidazoles; Ouabain; Pyridines; Receptor, Angiotensin, Type 2; Saponins; Signal Transduction; Tetradecanoylphorbol Acetate; Zona Glomerulosa	1998
Endogenous digitalis-like factor and ouabain immunoreactivity in adrenalectomized patients and normal subjects after acute and prolonged salt loading. American journal of hypertension, 1998, Volume: 11, Issue:1 Pt 1 Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Humans; Ouabain; Placenta; Renin; Saponins; Sodium, Dietary	1998
Isolation, visualization, characterization, and osmotic reactivity of crayfish BLMV. The American journal of physiology, 1998, Volume: 274, Issue:3 Topics: Animals; Astacoidea; Biological Transport, Active; Calcium; Cell Fractionation; Cell Membrane; Cell Polarity; Digestive System; Gills; Methods; Ouabain; Saponins; Sodium; Subcellular Fractions; Water-Electrolyte Balance	1998
Exogenous ouabain is accumulated in the adrenals and mimics the kinetics of endogenous digitalis-like factor in rats. Hypertension research : official journal of the Japanese Society of Hypertension, 1998, Volume: 21, Issue:1 Topics: Adrenal Cortex; Adrenalectomy; Animals; Autoradiography; Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Cross Reactions; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Kidney; Kinetics; Nephrectomy; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saponins; Tissue Distribution; Tritium	1998
Detection of endogenous digitalis-like immunoreactive factors in human blood. Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1998, Volume: 22, Issue:3 Topics: Animals; Antibodies; Antibodies, Monoclonal; Cardenolides; Digoxin; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Ouabain; Rabbits; Saponins; Sodium-Potassium-Exchanging ATPase	1998
Stimulatory effects of starfish sapogenins (Asterias amurensis and Lethasterias nanimensis chelifera) on molluscan heart (Spisula sachalinensis). Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1998, Volume: 120, Issue:2 Topics: Animals; Brain; Calcium; Cell Membrane; Cholestenones; Enzyme Inhibitors; Heart; Hemolysis; Humans; Mollusca; Myocardial Contraction; Ouabain; Pregnenes; Rats; Sapogenins; Saponins; Sodium-Potassium-Exchanging ATPase; Starfish; Sterols; Tumor Cells, Cultured	1998
Sodium pump inhibition and regional expression of sodium pump alpha-isoforms in lens. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:5 Topics: Animals; Brain; Cardenolides; Cataract; Cattle; Digoxin; Enzyme Inhibitors; Humans; Immunohistochemistry; Isoenzymes; Lens, Crystalline; Ouabain; Rabbits; Rats; Rats, Sprague-Dawley; Saponins; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary	1999
Inhibitors of Na-K-ATPase in human urine: effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: comparison with the effects of ouabain, angiotensin II, and arginine-vasopressin. American journal of hypertension, 2000, Volume: 13, Issue:4 Pt 1 Topics: Adult; Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Ascorbic Acid; Biological Factors; Biological Transport; Calcium; Calcium Channel Blockers; Cardenolides; Cells, Cultured; Digoxin; Enzyme Inhibitors; Gallic Acid; Humans; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Nickel; Organometallic Compounds; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents; Verapamil	2000
Ouabain augments Ca(2+) transients in arterial smooth muscle without raising cytosolic Na(+). American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:2 Topics: Animals; Arginine Vasopressin; Biological Factors; Calcium; Calcium Signaling; Cardenolides; Cardiotonic Agents; Cells, Cultured; Cytosol; Digoxin; Humans; Kinetics; Mesenteric Arteries; Models, Cardiovascular; Muscle, Smooth, Vascular; Ouabain; Phenylephrine; Potassium; Rats; Saponins; Serotonin; Sodium; Tetrodotoxin	2000
Liquid chromatography mass spectrometric analysis of ouabainlike factor in biological fluid. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Animals; Cardenolides; Cardiotonic Agents; Chromatography, Liquid; Digoxin; Humans; Hypertension; Mass Spectrometry; Ouabain; PC12 Cells; Rats; Saponins	2000
Analysis of human ouabainlike compound by micellar electrokinetic chromatography. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Digoxin; Humans; Hypertension; Ouabain; Saponins	2000
Receptor occupancy with digoxin vs receptor occupancy with a putative endogenous digitalislike factor. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Binding, Competitive; Cardenolides; Cardiotonic Agents; Digoxin; Humans; In Vitro Techniques; Muscle, Skeletal; Myocardium; Ouabain; Radioligand Assay; Saponins; Sodium-Potassium-Exchanging ATPase; Tritium	2000
Binding of ouabain and human ouabainlike substance to different Na+, K+-ATPase isoforms. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Cardenolides; Cardiotonic Agents; Cerebral Cortex; Cross Reactions; Digoxin; Dogs; Humans; Isoenzymes; Kidney; Mice; Mice, Inbred BALB C; Ouabain; Rabbits; Saponins; Sodium-Potassium-Exchanging ATPase; Species Specificity; Swine	2000
Digitalis and digitalislike compounds down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: 14-3-3 Proteins; Animals; Blotting, Northern; Bufanolides; Cardenolides; Cardiotonic Agents; Crystallins; Digoxin; Gene Expression; Lens, Crystalline; Ouabain; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saponins; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Tyrosine 3-Monooxygenase	2000
Different effects of in vivo ouabain and digoxin on renal artery function and blood pressure in the rat. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23 Suppl Topics: Acetylcholine; Animals; Blood Pressure; Caffeine; Cardenolides; Cardiotonic Agents; Digoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension, Renal; In Vitro Techniques; Male; Ouabain; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Rats; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Saponins; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Vasodilator Agents	2000
Endogenous Na,K pump ligands are differentially regulated during acute NaCl loading of Dahl rats. Circulation, 2000, Dec-12, Volume: 102, Issue:24 Topics: Animals; Blood Pressure; Bufanolides; Cardenolides; Digoxin; Electrolytes; Enzyme Inhibitors; Ion Pumps; Male; Ouabain; Potassium; Rats; Rats, Inbred Dahl; Saponins; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase	2000
Application of supercritical fluid chromatography to characterize a labile digitalis-like factor. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:6 Topics: Cardenolides; Chromatography, Gas; Chromatography, High Pressure Liquid; Digoxin; Enzyme Inhibitors; Humans; Hypertension; Kidney Failure, Chronic; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	2000
Identification of endogenous ouabain in culture supernatant of PC12 cells. Journal of hypertension, 2001, Volume: 19, Issue:2 Topics: Animals; Cardenolides; Culture Media; Digoxin; Enzyme-Linked Immunosorbent Assay; Ouabain; PC12 Cells; Progesterone; Rats; Saponins	2001
Human adrenal cells in culture produce both ouabain-like and dihydroouabain-like factors. Clinical chemistry, 2002, Volume: 48, Issue:10 Topics: Adrenal Glands; Biological Factors; Bucladesine; Cardenolides; Cells, Cultured; Chromatography, High Pressure Liquid; Digoxin; Humans; Immune Sera; Immunoenzyme Techniques; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	2002
Calpain is a mediator of myocardial injury in experimental uremia: is it activated by endogenous ouabain? Kidney international. Supplement, 2003, Issue:84 Topics: Calpain; Cardenolides; Cardiotonic Agents; Cells, Cultured; Digoxin; Enzyme Activation; Humans; Myoblasts, Cardiac; Ouabain; Saponins; Uremia	2003
Increases in CSF [Na+] precede the increases in blood pressure in Dahl S rats and SHR on a high-salt diet. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:3 Topics: Animals; Aorta, Abdominal; Blood Pressure; Brain; Cardenolides; Cardiotonic Agents; Digoxin; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Osmolar Concentration; Ouabain; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Saponins; Sodium; Sodium Chloride, Dietary; Telemetry	2004
Ouabain-like compound changes rapidly on physical exercise in humans and dogs: effects of beta-blockade and angiotensin-converting enzyme inhibition. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:5 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atenolol; Benzazepines; Cardenolides; Dogs; Enzyme-Linked Immunosorbent Assay; Exercise; Exercise Test; Female; Humans; Male; Motor Activity; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase	2005
Endogenous digitalis-like ligands and Na/K-ATPase inhibition in experimental diabetes mellitus. Frontiers in bioscience : a journal and virtual library, 2005, Sep-01, Volume: 10 Topics: Animals; ATPase Inhibitory Protein; Cardenolides; Diabetes Mellitus, Experimental; Male; Ouabain; Proteins; Rats; Rats, Wistar; Saponins; Sodium-Potassium-Exchanging ATPase	2005
Radioimmunoassays, ouabain-like material, and ouabain. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:3 Topics: Animals; Cardenolides; Dogs; Exercise; Humans; Motor Activity; Osmolar Concentration; Ouabain; Radioimmunoassay; Saponins	2005
Digoxin-like immunoreactive factors induce apoptosis in human acute T-cell lymphoblastic leukemia. Clinical chemistry, 2007, Volume: 53, Issue:7 Topics: Adolescent; Apoptosis; Cardenolides; Caspase 3; Cell Line, Tumor; Cell Survival; Cells, Cultured; Digoxin; Fas Ligand Protein; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Ouabain; RNA, Messenger; Saponins; Sodium-Potassium-Exchanging ATPase	2007
Mechanisms of hypertension. The New England journal of medicine, 2007, Aug-23, Volume: 357, Issue:8 Topics: Cardenolides; Humans; Hypertension; Ouabain; Potassium; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase	2007
Mechanisms of hypertension. The New England journal of medicine, 2007, Aug-23, Volume: 357, Issue:8 Topics: Cardenolides; Humans; Hypertension; Ouabain; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase	2007
Gene expression profiling of the proliferative effect of periplocin on mouse cardiac microvascular endothelial cells. Chinese journal of integrative medicine, 2010, Volume: 16, Issue:1 Topics: Animals; Animals, Newborn; Cardiac Glycosides; Cardiotonic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Coronary Vessels; Drug Evaluation, Preclinical; Endothelial Cells; Gene Expression Profiling; Gene Expression Regulation; Mice; Microvessels; Models, Biological; Myocardium; Oligonucleotide Array Sequence Analysis; Ouabain; Saponins	2010
Selective inhibition of the cellular sodium pump by emicymarin and 14ß anhydroxy bufadienolides. Steroids, 2010, Dec-12, Volume: 75, Issue:13-14 Topics: Animals; Bufanolides; Dogs; Enzyme Inhibitors; Erythrocytes; Humans; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Stereoisomerism	2010
Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction. European heart journal, 2012, Volume: 33, Issue:11 Topics: Animals; Calcium; Cardenolides; Fibrosis; Heart Failure; Heart Ventricles; Myofibroblasts; Ouabain; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Saponins; Sodium-Calcium Exchanger; Stroke Volume; Tibia	2012
Hypertension from chronic central sodium chloride in mice is mediated by the ouabain-binding site on the Na,K-ATPase α₂-isoform. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:5 Topics: Animals; Binding Sites; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brain; Cardenolides; Disease Models, Animal; Heart Rate; Hypertension; Infusions, Intraventricular; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Ouabain; Saponins; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Telemetry; Time Factors	2011
Normal pregnancy: mechanisms underlying the paradox of a ouabain-resistant state with elevated endogenous ouabain, suppressed arterial sodium calcium exchange, and low blood pressure. American journal of physiology. Heart and circulatory physiology, 2012, Mar-15, Volume: 302, Issue:6 Topics: Adrenal Glands; Animals; Arteries; Blood Pressure; Calcium; Cardenolides; Cardiotonic Agents; Chromatography, Liquid; Down-Regulation; Drug Resistance; Female; Fetal Growth Retardation; Homeostasis; Infusions, Subcutaneous; Mass Spectrometry; Ouabain; Peptides, Cyclic; Placenta; Placentation; Pregnancy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Saponins; Sodium-Calcium Exchanger; Time Factors; TRPC Cation Channels; Up-Regulation	2012
The effect of saponins from Ampelozizyphus amazonicus Ducke on the renal Na+ pumps' activities and urinary excretion of natriuretic peptides. BMC complementary and alternative medicine, 2012, Apr-11, Volume: 12 Topics: Adenosine Triphosphatases; Animals; Atrial Natriuretic Factor; Cation Transport Proteins; Diuresis; Enzyme Inhibitors; Furosemide; Kidney; Male; Ouabain; Plant Extracts; Rats; Rats, Wistar; Rhamnaceae; Saponins; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Urination	2012
Nanomolar ouabain increases NCX1 expression and enhances Ca2+ signaling in human arterial myocytes: a mechanism that links salt to increased vascular resistance? American journal of physiology. Heart and circulatory physiology, 2012, Oct-01, Volume: 303, Issue:7 Topics: Adolescent; Adult; Aged; Animals; Blood Pressure; Blotting, Western; Calcium Signaling; Cardenolides; Cell Membrane; Cell Shape; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Homeostasis; Humans; Hypertension; Immunohistochemistry; Inositol 1,4,5-Trisphosphate Receptors; Male; Mammary Arteries; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Ouabain; Rats; Saponins; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium Chloride; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Time Factors; TRPC Cation Channels; Up-Regulation; Vascular Resistance; Young Adult	2012
Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma. Oncotarget, 2015, Sep-15, Volume: 6, Issue:27 Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Proliferation; Cytosol; Flow Cytometry; Glioblastoma; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Ouabain; Potassium; Protein Structure, Tertiary; Rhodamines; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase	2015