osemozotan has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 7 studies
Studies (osemozotan) | Trials (osemozotan) | Recent Studies (post-2010) (osemozotan) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
---|---|---|---|---|---|
32 | 0 | 4 | 3,530 | 7 | 389 |
Protein | Taxonomy | osemozotan (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
---|---|---|---|
5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (57.14) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Asano, S; Baba, A; Matsuda, T; Somboonthum, P; Suzuki, M; Takuma, K | 1 |
Asano, S; Baba, A; Matsuda, T; Somboonthum, P; Suzuki, M | 1 |
Abe, M; Asano, S; Baba, A; Matsuda, T; Somboonthum, P; Tasaki, H; Yoshikawa, T | 1 |
Akiyama, M; Ikeda, M; Moriya, T; Shibata, S; Yokota, S; Yoshinobu, Y | 1 |
Aida, R; Akiyama, M; Moriya, T; Shibata, S; Shimomura, H; Takahashi, S; Yoshinobu, Y | 1 |
Ago, Y; Baba, A; Matsuda, T; Sakaue, M | 2 |
7 other study(ies) available for osemozotan and 8-hydroxy-2-(di-n-propylamino)tetralin
Article | Year |
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Increase of noradrenaline release in the hypothalamus of freely moving rat by postsynaptic 5-hydroxytryptamine1A receptor activation.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dioxanes; Dioxoles; Drug Interactions; Hippocampus; Hypothalamus; Injections, Subcutaneous; Male; Microdialysis; Neurons; Norepinephrine; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 1995 |
Antidepressant-like effect by postsynaptic 5-HT1A receptor activation in mice.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Depression; Dioxanes; Dioxoles; Fenclonine; Male; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Neurotransmitter; Serotonin Agents; Serotonin Receptor Agonists; Swimming | 1995 |
Interaction of orally administered 5-[3-[((2S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy]-1,3-benzodioxole (MKC-242) with 5-HT1A receptors in rat brain.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Dioxanes; Dioxoles; Male; Neurons; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Agents; Serotonin Receptor Agonists | 1997 |
Potentiating action of MKC-242, a selective 5-HT1A receptor agonist, on the photic entrainment of the circadian activity rhythm in hamsters.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Dioxanes; Dioxoles; Geniculate Ganglion; Hydroxyindoleacetic Acid; Light; Male; Mesocricetus; Motor Activity; Photic Stimulation; Proto-Oncogene Proteins c-fos; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus | 1998 |
Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Cell Cycle Proteins; Circadian Rhythm; Diazepam; Dioxanes; Dioxoles; GABA Modulators; Gene Expression Regulation; In Situ Hybridization; Light; Male; Mice; Motor Activity; Nuclear Proteins; Paroxetine; Period Circadian Proteins; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Suprachiasmatic Nucleus; Transcription Factors | 2002 |
Selective reduction by isolation rearing of 5-HT1A receptor-mediated dopamine release in vivo in the frontal cortex of mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Dioxanes; Dioxoles; Dopamine; Dopamine Uptake Inhibitors; Frontal Lobe; Male; Mice; Mice, Inbred Strains; Microdialysis; Norepinephrine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Social Isolation | 2002 |
The 5-HT1A receptor agonist MKC-242 reverses isolation rearing-induced deficits of prepulse inhibition in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Administration, Oral; Animals; Apomorphine; Dioxanes; Dioxoles; Dizocilpine Maleate; Drug Interactions; Male; Mice; Piperazines; Pyridines; Reflex, Startle; Risperidone; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Social Isolation | 2003 |