Compounds > oseltamivir
Page last updated: 2024-08-24

oseltamivir and ribavirin

oseltamivir has been researched along with ribavirin in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (3.61)18.2507
2000's17 (20.48)29.6817
2010's51 (61.45)24.3611
2020's12 (14.46)2.80

Authors

AuthorsStudies
Bailey, KW; Barnard, DL; Day, CW; Furuta, Y; Morrey, JD; Sidwell, RW; Smee, DF; Wong, MH1
Andricopulo, AD; Moda, TL; Montanari, CA1
De Clercq, E; Gawin, R; Koszytkowska-Stawińska, M; Naesens, L1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Balzarini, J; Brancale, A; Cirilli, R; Coluccia, A; Giordano, C; La Regina, G; La Torre, F; Lavecchia, A; Maga, G; Novellino, E; Piscitelli, F; Samuele, A; Sansone, A; Silvestri, R; Zanoli, S1
Batta, G; Herczegh, P; Kéki, S; Komáromi, I; Mándi, A; Naesens, L; Ostorházi, E; Pintér, G; Röth, E; Rozgonyi, F; Sztaricskai, F; Takács-Novák, K1
Batta, G; Bereczki, I; Boda, Z; Herczegh, P; Naesens, L; Ostorházi, E; Otvös, R; Pintér, G; Roth, E; Rozgonyi, F; Szarvas, M; Sztaricskai, F1
De Clercq, E; Ganguly, S; Kumar, KS; Veerasamy, R1
Balzarini, J; De Clercq, E; Dewan, SK; Kumar, P; Narasimhan, B; Pannecouque, C; Yadav, S1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Balzarini, J; Głowacka, IE; Piotrowska, DG1
Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K1
Hao, LH; He, WY; Jiang, JD; Li, YH; Li, YP; Li, ZR; Shan, GZ; Wang, HQ1
Day, CW; Grellier, P; Havrylyuk, D; Lesyk, R; Smee, DF; Vasylenko, O; Zimenkovsky, B1
Balzarini, J; Chibale, K; Kaur, H; Singh, K1
Balzarini, J; Singh, K1
Aisa, HA; Dong, CZ; He, YW; Li, YH; Ma, LL; Zhao, JY1
Fernández, R; Font-Bardia, M; Miquet, S; Naesens, L; Torres, E; Vanderlinden, E; Vázquez, S1
Chen, X; Lin, W; Liu, D; Proksch, P; Si, L; Zhang, L; Zhou, D1
Batta, G; Bereczki, I; Borbás, A; Fizil, Á; Herczegh, P; Komáromi, I; Kurtán, T; Mándi, A; Naesens, L; Ostorházi, E; Rőth, E; Rozgonyi, F; Sipos, A; Sztaricskai, F; Vanderlinden, E1
Hou, Q; Jiang, JD; Li, L; Li, Y; Li, YH; Liu, YB; Ma, SG; Qu, J; Shi, YS; Yu, SS; Yuan, SP1
Hua, J; Huang, FP; Li, YH; Liang, D; Pan, QM; Wang, HS1
Lin, W; Liu, D; Niu, S; Shao, Z; Si, L; Wang, S; Zhang, L; Zhang, Z; Zhou, A; Zhou, D1
Botta, M; de Esch, I; Deodato, D; Edink, E; Fallacara, AL; Gospodova, T; Loregian, A; Mercorelli, B; Nannetti, G; Palù, G; Tintori, C; Trist, IM; Verheij, M; Viteva, L; Wijtmans, M1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Aisa, HA; Dong, CZ; Li, G; Nie, LF; Niu, C; Zhao, JY1
Andrei, G; Pertusati, F; Pileggi, E; Schols, D; Serpi, M; Snoeck, R1
Orshanskaya, IR; Salakhutdinov, NF; Semenova, MD; Shtro, AA; Sokolova, AS; Yarovaya, OI; Zarubaev, VV1
Aisa, HA; Li, G; Liu, GY; Lu, W; Obul, M; Zhao, JY1
Balzarini, J; De Clercq, E; Karki, SS; Kulkarni, AA; Kumar, S; Veliyath, SK1
Cen, S; Chen, J; Jiang, X; Jiang, Z; Jin, J; Li, J; Li, Y; Li, Z; Peng, Z; Quan, Y; Tan, J; Wang, Y1
Duan, Z; Gu, Q; Li, D; Li, J; Liu, Y; Wang, W; Wu, G; Yang, S; Yu, G; Yu, R; Yu, Y; Zhu, T1
Gao, R; Jiang, J; Li, Y; Liu, M; Lv, K; Ma, C; Qin, X; Wang, A; Wei, Z; Xu, S; Yan, H; Zhang, K1
Boryczka, S; Chrobak, E; Orzechowska, B; Pęcak, P1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bailey, KW; Barnard, DL; Huffman, JH; Kim, CU; Morrison, A; Sidwell, RW; Syndergaard, T; Wong, MH1
Keating, MR1
Babu, YS; Bailey, KW; Barnard, DL; Huffman, JH; Morrey, JD; Sidwell, RW; Smee, DF1
Bailey, KW; Barnard, DL; Jackson, MK; Sidwell, RW; Smee, DF; Wong, MH1
Boas, LS; da Rocha, IF; Dulley, FL; Machado, CM; Mendes, AV; Pannuti, CS; Santos, MF; Sturaro, D1
Bailey, KW; Sidwell, RW; Smee, DF; Wandersee, MK; Wong, MH1
Jonsson, CB; Noah, DL; Noah, JW; Rasmussen, L; Severson, W; White, EL1
Bailey, KW; Sidwell, RW; Smee, DF; Wong, MH1
Lynch, JP; Walsh, EE1
Boon, AC; Govorkova, EA; Hay, A; Ilyushina, NA; Webster, RG; Yilmaz, N1
Bailey, KW; Hurst, BL; Morrey, JD; Smee, DF; Wong, MH1
Driebe, EM; Engelthaler, DM; Hoopes, JD; Keim, PS; Le, MH; Nguyen, JT; Prichard, MN; Smee, DF; Spence, RP; Went, GT1
Ariano, RE; Smith, JR; Toovey, S1
Burke, JD; Fish, EN1
Furuta, Y; Kawaoka, Y; Kiso, M; Le, QM; Ozawa, M; Sakabe, S; Sakai-Tagawa, Y; Shinya, K; Takahashi, K1
Blair, PJ; de Jong, MD; Faix, DJ; Hoopes, JD; Le, MH; Nguyen, JT; Patick, AK; Prichard, MN; Smee, DF; Went, GT1
Barnard, DL; Dagley, A; Hagloch, J; Julander, JG; Latimer, S; Morrey, JD; Motter, N; Smee, DF1
Deriabin, PG; Fediakina, IT; Gudova, NV; Kondrat'eva, TV; L'vov, DK; Leneva, IA; Shchelkanov, MIu1
Razonable, RR1
Choi, SH; Chon, GR; Han, MS; Hong, SB; Huh, JW; Kim, HR; Kim, MJ; Kim, SH; Kim, WY; Kim, YS; Ko, YG; Lee, KH; Ryu, YJ; Young Suh, G1
Driebe, EM; Engelthaler, DM; Hoopes, JD; Keim, PS; Kelley, E; Nguyen, JT; Perelson, AS; Rong, L; Went, GT1
Buti, M; Esteban, R; Simón-Talero, M1
Jurkuvenaite, A; Matalon, S; Noah, DL; Noah, JW; Steele, C; Zarogiannis, SG1
Barnard, DL; de Jong, MD; Gross, M; Julander, JG; Nguyen, JT; Smee, DF; Went, GT1
Hodge, TW; McDonald, NJ; Murray, JL; O'Brien, WA; Rubin, DH; Shaw, MW; Sheng, J; Smee, DF1
Cen, S; He, Z; Li, XY; Liu, ZL; Wang, X; Wang, Z; Wei, XL; Yin, X; Zhang, ZZ; Zhou, JM1
Boeckh, MJ; de Jong, MD; Englund, JA; Lindegardh, N; Nguyen, JT; Pukrittayakamee, S; Renaud, C; Seo, S; Tambyah, PA; Tarning, J; Went, GT1
Luvisi, A; Panattoni, A; Rinaldelli, E; Triolo, E1
Jang, HC; Jung, SI; Kang, SJ; Kee, SJ; Kwon, YS; Park, KH; Shin, JH1
An, L; Chen, X; Liao, Q; Liu, R; Qian, Z1
Deryabin, PG; Galegov, GA; Konstantinova, ID; L'vov, DK; Miroshnikov, AI; Muzyka, IS1
Chung, ST; Hsiung, HY; Huang, WH; Huang, YT; Lee, AR; Yao, CW1
Böttcher-Friebertshäuser, E; Dahms, SO; Garten, W; Hardes, K; Klenk, HD; Lu, Y; Steinmetzer, T; Than, ME1
Hussain, M; Jin, R; Li, M; Li, X; Lin, C; Liu, X; Sun, C; Tu, Z; Wan, J; Zhang, J; Zhou, Y1
Dou, J; Jin, J; Li, M; Wang, D; Wang, H; Xu, J; Yu, J; Zhou, C1
Berger, A; Christopeit, M; Hauf, E; Hentrich, M; Heussel, CP; Kalkreuth, J; Klein, M; Kochanek, M; Lehners, N; Mayer, K; Penack, O; Rieger, C; Schalk, E; Silling, G; Vehreschild, M; von Lilienfeld-Toal, M; Weber, T; Wolf, HH1
Ariza-Heredia, EJ; Chemaly, RF; Shahani, L1
Bao, Y; Beasley, RL; Beeler, J; Beigel, JH; Bozzolo, DR; Dar, SM; Davey, RT; Holley, HP; Hoopes, J; Hughes, MD; Lane, HC; Losso, MH; Manosuthi, W; McClure, N; Myers, C; Panuto, J; Perez-Patrigeon, S; Slandzicki, A; Suwanpimolkul, G1
Cutrell, JB; Jodlowski, TZ; Monogue, ML; Sanders, JM1
He, J; Huang, D; Li, J; Liang, W; Liu, L; Xia, Z; Xu, X; Zhao, Y1
Abed, Y; Baz, M; Boivin, G; Checkmahomed, L; Padey, B; Pizzorno, A; Rosa-Calatrava, M; Terrier, O1
Wen, S; Xu, X; Yadav, AK; Yu, L1
Anedda, L; Bianchini, L; Cuzzolin, L; Fanos, V; Finco, G; Marcialis, MA1
Ding, YL; Hu, CC; Li, WF; Yuan, B1
Cheng, Y; Cui, M; Ding, Y; He, W; Li, L; Li, X; Li, Z; Tian, A; Yang, C; Zhao, Z; Zou, X1

Reviews

12 review(s) available for oseltamivir and ribavirin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiviral agents for non-human immunodeficiency virus infections.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir

1999
Influenza: evolving strategies in treatment and prevention.
    Seminars in respiratory and critical care medicine, 2007, Volume: 28, Issue:2

    Topics: Aged; Amantadine; Antiviral Agents; Centers for Disease Control and Prevention, U.S.; Child, Preschool; Humans; Infant; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Oseltamivir; Practice Guidelines as Topic; Ribavirin; Rimantadine; United States; Zanamivir

2007
The use of antiviral agents for the management of severe influenza.
    Critical care medicine, 2010, Volume: 38, Issue:4 Suppl

    Topics: Age Factors; Antiviral Agents; Drug Therapy, Combination; Humans; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferons; Length of Stay; Neuraminidase; Oseltamivir; Practice Guidelines as Topic; Ribavirin; Risk Factors; Viral Load; Zanamivir

2010
Antiviral strategies: the present and beyond.
    Current molecular pharmacology, 2009, Volume: 2, Issue:1

    Topics: Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Influenza, Human; Interferon-alpha; Oseltamivir; Ribavirin; Structure-Activity Relationship

2009
Antiviral drugs for viruses other than human immunodeficiency virus.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:10

    Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir

2011
Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 67

    Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Community-Acquired Infections; Cytosine; Germany; Hand Hygiene; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Influenza, Human; Lung; Masks; Medical Oncology; Metapneumovirus; Neoplasms; Neuraminidase; Nucleic Acid Amplification Techniques; Organophosphonates; Oseltamivir; Paramyxoviridae Infections; Patient Isolation; Pneumonia, Viral; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Ribavirin; Tomography, X-Ray Computed; Virus Diseases

2016
Antiviral therapy for respiratory viral infections in immunocompromised patients.
    Expert review of anti-infective therapy, 2017, Volume: 15, Issue:4

    Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Coronavirus Infections; Cyclopentanes; Guanidines; Humans; Immunocompromised Host; Influenza, Human; Oseltamivir; Palivizumab; Paramyxoviridae Infections; Picornaviridae Infections; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Ribavirin; Zanamivir

2017
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review.
    JAMA, 2020, May-12, Volume: 323, Issue:18

    Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Immunoglobulins; Immunologic Factors; Indoles; Lopinavir; Oseltamivir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Withholding Treatment

2020
Antiviral treatment in COVID-19: which is the most promising?-a narrative review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azetidines; Chloroquine; COVID-19; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Oseltamivir; Purines; Pyrazines; Pyrazoles; Ribavirin; Ritonavir; Sulfonamides; Thiazoles

2021
What if COVID-19 affects the child: which weapons and how to use them.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:8

    Topics: Adenosine Monophosphate; Adolescent; Age Factors; Alanine; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiviral Agents; Carrier State; Child; Child, Preschool; Chloroquine; Continuous Renal Replacement Therapy; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Drug Combinations; Extracorporeal Membrane Oxygenation; Glucocorticoids; Humans; Hydroxychloroquine; Immunization, Passive; Immunoglobulins, Intravenous; Immunologic Factors; Infant; Infant, Newborn; Interferon-alpha; Lopinavir; Oseltamivir; Receptors, Cell Surface; Respiration, Artificial; Ribavirin; Ritonavir; SARS-CoV-2; Severity of Illness Index; Thrombosis

2021
[Overview of Meta-analysis of Lianhua Qingwen preparations in treatment of viral diseases].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:16

    Topics: Cough; COVID-19 Drug Treatment; Drugs, Chinese Herbal; Fatigue; Fever; Humans; Influenza, Human; Meta-Analysis as Topic; Nonprescription Drugs; Nucleic Acids; Oseltamivir; Ribavirin

2022

Trials

2 trial(s) available for oseltamivir and ribavirin

ArticleYear
Combination therapy with amantadine, oseltamivir and ribavirin for influenza A infection: safety and pharmacokinetics.
    Antiviral therapy, 2013, Volume: 18, Issue:3

    Topics: Adult; Amantadine; Drug Resistance, Viral; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Influenza A virus; Influenza, Human; Male; Mutation; Oseltamivir; Pilot Projects; Ribavirin; Viral Load; Young Adult

2013
Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial.
    The Lancet. Infectious diseases, 2017, Volume: 17, Issue:12

    Topics: Amantadine; Antiviral Agents; Argentina; Australia; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Influenza, Human; Male; Mexico; Oseltamivir; Ribavirin; Thailand; United States

2017

Other Studies

69 other study(ies) available for oseltamivir and ribavirin

ArticleYear
Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Amides; Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; Oseltamivir; Oxygen; Pyrazines; Survival Analysis; Virus Replication

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Animals; Antiviral Agents; Aza Compounds; Catalysis; Cell Line; DNA Viruses; Drug Resistance, Viral; Humans; Hydrogenation; Nucleosides; Palladium; Pyrimidine Nucleosides; RNA Viruses; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
    Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7

    Topics: Amino Acids; Animals; Anti-HIV Agents; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Drug Resistance, Viral; Enterovirus B, Human; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Lymphocytes; Mice; Models, Molecular; Molecular Conformation; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Sulfones; Virus Replication

2009
Diazo transfer-click reaction route to new, lipophilic teicoplanin and ristocetin aglycon derivatives with high antibacterial and anti-influenza virus activity: an aggregation and receptor binding study.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Anti-Bacterial Agents; Antiviral Agents; Diazonium Compounds; Doxorubicin; Gram-Positive Bacteria; Microbial Sensitivity Tests; Orthomyxoviridae; Teicoplanin

2009
Click reaction synthesis of carbohydrate derivatives from ristocetin aglycon with antibacterial and antiviral activity.
    Bioorganic & medicinal chemistry letters, 2010, May-01, Volume: 20, Issue:9

    Topics: Anti-Bacterial Agents; Antiviral Agents; Catalysis; Copper; Doxorubicin; Humans; Influenza A Virus, H1N1 Subtype; Microbial Sensitivity Tests; Ristocetin

2010
Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Quinazolines; Schiff Bases; Spectrophotometry, Infrared

2010
4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Animals; Anti-Infective Agents; Benzenesulfonates; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Dogs; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses

2010
New prodrugs of Adefovir and Cidofovir.
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.
    European journal of medicinal chemistry, 2012, Volume: 47, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cytostatic Agents; Drug Design; Humans; Inhibitory Concentration 50; Mice; Nucleotides; Triazoles; Viruses

2012
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses

2012
Synthesis and antiviral activity of substituted bisaryl amide compounds as novel influenza virus inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 55

    Topics: Amides; Antiviral Agents; Chemistry Techniques, Synthetic; Influenza A Virus, H1N1 Subtype; Influenza B virus; Structure-Activity Relationship

2012
Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Antineoplastic Agents; Antiprotozoal Agents; Antiviral Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Pyrazoles; Structure-Activity Relationship; Thiazolidines; Trypanosoma brucei brucei; Viruses

2013
Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Antimalarials; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA; Heme; Humans; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship

2013
Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses

2013
1,2,3-Triazole-containing derivatives of rupestonic acid: click-chemical synthesis and antiviral activities against influenza viruses.
    European journal of medicinal chemistry, 2014, Apr-09, Volume: 76

    Topics: Antiviral Agents; Azulenes; Click Chemistry; Magnetic Resonance Spectroscopy; Orthomyxoviridae; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Triazoles

2014
Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds.
    ACS medicinal chemistry letters, 2012, Dec-13, Volume: 3, Issue:12

    Topics:

2012
Neoechinulin B and its analogues as potential entry inhibitors of influenza viruses, targeting viral hemagglutinin.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Alkaloids; Animals; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cytopathogenic Effect, Viral; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Viral; Eurotium; HEK293 Cells; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Molecular Structure; Piperazines; Structure-Activity Relationship; Viral Plaque Assay

2015
A few atoms make the difference: synthetic, CD, NMR and computational studies on antiviral and antibacterial activities of glycopeptide antibiotic aglycon derivatives.
    European journal of medicinal chemistry, 2015, Apr-13, Volume: 94

    Topics: Anti-Bacterial Agents; Antiviral Agents; Chemistry Techniques, Synthetic; Circular Dichroism; Computer Simulation; Magnetic Resonance Spectroscopy; Orthomyxoviridae; Protein Conformation; Ristocetin; Structure-Activity Relationship; Teicoplanin

2015
Bioactive Sesquiterpenes and Lignans from the Fruits of Xanthium sibiricum.
    Journal of natural products, 2015, Jul-24, Volume: 78, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Crystallography, X-Ray; Dogs; Drugs, Chinese Herbal; Fruit; Influenza A Virus, H1N1 Subtype; Inhibitory Concentration 50; Lignans; Macrophages; Madin Darby Canine Kidney Cells; Mice; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sesquiterpenes; Vero Cells; Xanthium

2015
Antiviral Matrine-Type Alkaloids from the Rhizomes of Sophora tonkinensis.
    Journal of natural products, 2015, Jul-24, Volume: 78, Issue:7

    Topics: Alkaloids; Antiviral Agents; Influenza A Virus, H3N2 Subtype; Inhibitory Concentration 50; Matrines; Molecular Structure; Quinolizines; Rhizome; Sophora; Stereoisomerism

2015
Spiromastilactones: A new class of influenza virus inhibitors from deep-sea fungus.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Animals; Antiviral Agents; Aquatic Organisms; Benzofurans; Dogs; Dose-Response Relationship, Drug; Influenza A virus; Lactones; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Onygenales; Structure-Activity Relationship

2016
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Animals; Antiviral Agents; Crystallography, X-Ray; DNA-Directed RNA Polymerases; Dogs; Drug Design; HEK293 Cells; Humans; Influenza A virus; Influenza, Human; Madin Darby Canine Kidney Cells; Models, Molecular; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Viral Plaque Assay; Viral Proteins; Virus Replication

2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Structure-activity relationship studies of 1-(1'-hydroxyalkyl)rupestonic acid methyl esters against influenza viruses.
    Bioorganic & medicinal chemistry letters, 2017, 03-15, Volume: 27, Issue:6

    Topics: Antiviral Agents; Azulenes; Crystallography, X-Ray; Esters; Microbial Sensitivity Tests; Orthomyxoviridae; Sesquiterpenes; Structure-Activity Relationship

2017
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Antiviral Agents; Cell Line; DNA Viruses; Drug Stability; Humans; Nucleosides; Organophosphonates; Prodrugs; RNA Viruses; Structure-Activity Relationship

2018
Synthesis and
    MedChemComm, 2017, May-01, Volume: 8, Issue:5

    Topics:

2017
Novel amides modified rupestonic acid derivatives as anti-influenza virus reagents.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Amides; Antiviral Agents; Azulenes; Crystallography, X-Ray; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Sesquiterpenes

2019
Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-
    Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2013, Volume: 22, Issue:4

    Topics:

2013
2-((4-Arylpiperazin-1-yl)methyl)benzonitrile Derivatives as Orally Available Inhibitors of Hepatitis C Virus with a Novel Mechanism of Action.
    Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11

    Topics: Administration, Oral; Animals; Antiviral Agents; Cell Line; Dogs; Drug Design; Drug Resistance, Viral; Female; Half-Life; Hepacivirus; Humans; Male; Mice; Mutation; Nitriles; Rats; Structure-Activity Relationship; Virus Replication

2020
Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion.
    Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13

    Topics: Acetophenones; Adsorption; Animals; Antiviral Agents; Dogs; Drug Discovery; Drug Resistance, Viral; Female; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A virus; Madin Darby Canine Kidney Cells; Membrane Fusion; Mice; Tissue Distribution; Virus Internalization; Virus Replication

2020
Optimization and SAR research at the piperazine and phenyl rings of JNJ4796 as new anti-influenza A virus agents, part 1.
    European journal of medicinal chemistry, 2021, Oct-15, Volume: 222

    Topics: Antiviral Agents; Dose-Response Relationship, Drug; Influenza A Virus, H1N1 Subtype; Microbial Sensitivity Tests; Molecular Structure; Piperazine; Piperazines; Pyridines; Structure-Activity Relationship; Tetrazoles

2021
Novel betulin dicarboxylic acid ester derivatives as potent antiviral agents: Design, synthesis, biological evaluation, structure-activity relationship and in-silico study.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Antiviral Agents; Dicarboxylic Acids; DNA Viruses; Dose-Response Relationship, Drug; Drug Design; Esters; Microbial Sensitivity Tests; Molecular Structure; RNA Viruses; Structure-Activity Relationship; Triterpenes

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor.
    Antiviral research, 1998, Volume: 37, Issue:2

    Topics: Acetamides; Administration, Intranasal; Administration, Oral; Amines; Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Dogs; Enzyme Inhibitors; Female; Guanidines; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Lung Diseases; Mice; Mice, Inbred BALB C; Molecular Structure; Neuraminidase; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Zanamivir

1998
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 1999, Dec-03, Volume: 41, Issue:1067

    Topics: 2-Aminopurine; Acetamides; Acyclovir; Aged; Amantadine; Animals; Anti-HIV Agents; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enzyme Inhibitors; Famciclovir; Ganciclovir; Guanidines; Guanine; Herpes Simplex; Herpes Zoster; History, 18th Century; HIV Infections; Humans; Injections, Intravenous; Interferon-alpha; Lamivudine; Neuraminidase; Oseltamivir; Pyrans; Rats; Ribavirin; Sialic Acids; Teratogens; Valacyclovir; Valine; Zanamivir

1999
In vivo influenza virus-inhibitory effects of the cyclopentane neuraminidase inhibitor RJW-270201.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3

    Topics: Acetamides; Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Female; Guanidines; Influenza A virus; Influenza B virus; Lung; Mice; Mice, Inbred C57BL; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Respiratory Function Tests; Ribavirin; Virus Replication

2001
Utilization of alpha-1-acid glycoprotein levels in the serum as a parameter for in vivo assay of influenza virus inhibitors.
    Antiviral chemistry & chemotherapy, 2001, Volume: 12, Issue:6

    Topics: Acetamides; Animals; Antiviral Agents; Biomarkers; Female; Lung; Mice; Mice, Inbred BALB C; Orosomucoid; Orthomyxoviridae; Orthomyxoviridae Infections; Oseltamivir; Radioimmunoassay; Ribavirin; Time Factors

2001
Low mortality rates related to respiratory virus infections after bone marrow transplantation.
    Bone marrow transplantation, 2003, Volume: 31, Issue:8

    Topics: Acetamides; Aerosols; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Fluorescent Antibody Technique, Indirect; Hematologic Neoplasms; Humans; Influenza, Human; Oseltamivir; Paramyxoviridae Infections; Postoperative Complications; Respirovirus Infections; Ribavirin; Transplantation, Autologous; Transplantation, Homologous; Virus Shedding

2003
Treatment of mannan-enhanced influenza B virus infections in mice with oseltamivir, ribavirin and viramidine.
    Antiviral chemistry & chemotherapy, 2004, Volume: 15, Issue:5

    Topics: Acetamides; Administration, Oral; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Hong Kong; Influenza B virus; Lung; Mannans; Mice; Organ Size; Orthomyxoviridae Infections; Oseltamivir; Ribavirin; Survival Rate

2004
A cell-based luminescence assay is effective for high-throughput screening of potential influenza antivirals.
    Antiviral research, 2007, Volume: 73, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Dogs; Humans; Influenza A Virus, H3N2 Subtype; Luminescence; Microbial Sensitivity Tests; Neutral Red; Oseltamivir; Ribavirin

2007
Activities of oseltamivir and ribavirin used alone and in combination against infections in mice with recent isolates of influenza A (H1N1) and B viruses.
    Antiviral chemistry & chemotherapy, 2006, Volume: 17, Issue:4

    Topics: Administration, Oral; Animals; Antiviral Agents; Cells, Cultured; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Influenza A Virus, H1N1 Subtype; Influenza B virus; Mice; Orthomyxoviridae Infections; Oseltamivir; Placebos; Ribavirin; Time Factors

2006
Oseltamivir-ribavirin combination therapy for highly pathogenic H5N1 influenza virus infection in mice.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Animals; Antiviral Agents; Chemokines; Cytokines; Drug Interactions; Drug Therapy, Combination; Female; Influenza A Virus, H5N1 Subtype; Lung; Mice; Mice, Inbred BALB C; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Ribavirin; Virus Replication

2008
Effects of double combinations of amantadine, oseltamivir, and ribavirin on influenza A (H5N1) virus infections in cell culture and in mice.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Amantadine; Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Drug Interactions; Drug Resistance, Viral; Drug Therapy, Combination; Humans; Influenza A Virus, H5N1 Subtype; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Orthomyxoviridae Infections; Oseltamivir; Ribavirin; Specific Pathogen-Free Organisms; Treatment Outcome

2009
Triple combination of oseltamivir, amantadine, and ribavirin displays synergistic activity against multiple influenza virus strains in vitro.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Amantadine; Animals; Antiviral Agents; Cell Line; Dogs; Drug Synergism; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Orthomyxoviridae; Oseltamivir; Polymerase Chain Reaction; Ribavirin

2009
T-705 (favipiravir) activity against lethal H5N1 influenza A viruses.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2

    Topics: Aged; Amides; Animals; Antiviral Agents; Cell Line; Child; DNA Replication; DNA-Directed DNA Polymerase; Dogs; Drug Resistance, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Kidney; Kinetics; Lung; Oseltamivir; Pyrazines; Ribavirin

2010
Triple combination of amantadine, ribavirin, and oseltamivir is highly active and synergistic against drug resistant influenza virus strains in vitro.
    PloS one, 2010, Feb-22, Volume: 5, Issue:2

    Topics: Amantadine; Animals; Antiviral Agents; Cell Line; Drug Resistance, Viral; Drug Synergism; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Inhibitory Concentration 50; Orthomyxoviridae; Oseltamivir; Ribavirin

2010
Use of plethysmography in assessing the efficacy of antivirals in a mouse model of pandemic influenza A virus.
    Antiviral research, 2011, Volume: 92, Issue:2

    Topics: Animals; Antiviral Agents; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Influenza A Virus, H1N1 Subtype; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oseltamivir; Plethysmography; Ribavirin; Treatment Outcome

2011
[Susceptibility of pandemic influenza virus A 2009 H1N1 and highly pathogenic avian influenza virus A H5N1 to antiinfluenza agents in cell culture].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:3-4

    Topics: Animals; Antiviral Agents; Birds; Cell Line; Drug Resistance, Viral; Humans; Indoles; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Oseltamivir; Ribavirin; Rimantadine; Virus Replication

2011
Triple-combination antiviral drug for pandemic H1N1 influenza virus infection in critically ill patients on mechanical ventilation.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Cohort Studies; Critical Illness; Drug Therapy, Combination; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Korea; Male; Middle Aged; Oseltamivir; Pandemics; Respiration, Artificial; Retrospective Studies; Ribavirin; Treatment Outcome

2011
Triple combination antiviral drug (TCAD) composed of amantadine, oseltamivir, and ribavirin impedes the selection of drug-resistant influenza A virus.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Amantadine; Amino Acid Substitution; Animals; Antiviral Agents; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Influenza A virus; Oseltamivir; Phenotype; Ribavirin; Serial Passage; Suppression, Genetic

2011
Severe anaemia related to oseltamivir during treatment of chronic hepatitis C: a new drug interaction?
    Journal of viral hepatitis, 2012, Volume: 19 Suppl 1

    Topics: Adult; Anemia; Antiviral Agents; Drug Interactions; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferon alpha-2; Interferon-alpha; Oseltamivir; Polyethylene Glycols; Recombinant Proteins; Ribavirin

2012
Comparison of ribavirin and oseltamivir in reducing mortality and lung injury in mice infected with mouse adapted A/California/04/2009 (H1N1).
    Life sciences, 2012, Mar-10, Volume: 90, Issue:11-12

    Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; DNA Primers; Female; Influenza A Virus, H1N1 Subtype; Kaplan-Meier Estimate; Lung; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oseltamivir; Real-Time Polymerase Chain Reaction; Ribavirin

2012
Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Amantadine; Animals; Antiviral Agents; Cells, Cultured; Disease Models, Animal; Dogs; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Female; Influenza A Virus, H5N1 Subtype; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oseltamivir; Placebos; Ribavirin; Treatment Outcome

2012
Inhibition of influenza A virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis.
    Antiviral chemistry & chemotherapy, 2012, May-14, Volume: 22, Issue:5

    Topics: Animals; Antiviral Agents; Cell Line; Everolimus; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mutagenesis, Insertional; Oseltamivir; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA Interference; Sirolimus; TOR Serine-Threonine Kinases; Virus Replication

2012
[Establishment of drug screening assay and pharmacodynamic evaluation method targeting influenza RNA polymerase].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:9

    Topics: Alphainfluenzavirus; Amantadine; Antiviral Agents; Drug Evaluation, Preclinical; Genes, Reporter; HEK293 Cells; Humans; Luciferases; Oseltamivir; Plasmids; Reproducibility of Results; Ribavirin; RNA-Dependent RNA Polymerase; Sensitivity and Specificity; Transfection; Zanamivir

2012
In vivo inhibition of trans-plasma membrane electron transport by antiviral drugs in grapevine.
    The Journal of membrane biology, 2013, Volume: 246, Issue:7

    Topics: Antiviral Agents; Electron Transport; Enzyme Activation; Membrane Potentials; Membrane Transport Proteins; Oseltamivir; Oxidation-Reduction; Oxidoreductases; Plant Proteins; Ribavirin; Vitis

2013
Virological clearance rate of high-dose oseltamivir or triple-combination antiviral therapy in complicated 2009 pandemic influenza A (H1N1) infection.
    Japanese journal of infectious diseases, 2013, Volume: 66, Issue:5

    Topics: Adolescent; Adult; Aged; Amantadine; Antiviral Agents; Drug Therapy, Combination; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Oseltamivir; Respiratory Distress Syndrome; Ribavirin; Survival Analysis; Treatment Outcome

2013
Germacrone inhibits early stages of influenza virus infection.
    Antiviral research, 2013, Volume: 100, Issue:3

    Topics: Animals; Antiviral Agents; Cell Line; Chick Embryo; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Lung; Madin Darby Canine Kidney Cells; Mice; Orthomyxoviridae Infections; Oseltamivir; Phytotherapy; Ribavirin; Sesquiterpenes, Germacrane; Specific Pathogen-Free Organisms; Virus Attachment; Virus Cultivation; Virus Replication

2013
The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza A virus resistant to rimantadine (amantadine) in vitro and in vivo.
    Doklady. Biochemistry and biophysics, 2014, Volume: 455, Issue:1

    Topics: Amantadine; Animals; Antiviral Agents; Dogs; Drug Combinations; Drug Resistance, Viral; Influenza A virus; Madin Darby Canine Kidney Cells; Mice; Orthomyxoviridae Infections; Oseltamivir; Ribavirin; Virus Replication

2014
Novel daidzein analogs and their in vitro anti-influenza activities.
    Chemistry & biodiversity, 2015, Volume: 12, Issue:4

    Topics: Animals; Antiviral Agents; Chemistry Techniques, Synthetic; Dogs; Drug Evaluation, Preclinical; Drug Resistance, Viral; Influenza A Virus, H1N1 Subtype; Isoflavones; Madin Darby Canine Kidney Cells; Molecular Structure; Oseltamivir; Ribavirin; Structure-Activity Relationship

2015
Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.
    Antiviral research, 2015, Volume: 120

    Topics: Animals; Antiviral Agents; Dogs; Drug Resistance, Viral; Drug Synergism; Furin; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H7N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Mutant Proteins; Mutation, Missense; Neuraminidase; Oseltamivir; Peptidomimetics; Ribavirin; Viral Proteins

2015
Design, synthesis, and in vitro biological evaluation of novel 6-methyl-7-substituted-7-deaza purine nucleoside analogs as anti-influenza A agents.
    Antiviral research, 2016, Volume: 129

    Topics: Antiviral Agents; Drug Discovery; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Inhibitory Concentration 50; Microbial Sensitivity Tests; Oseltamivir; Purine Nucleosides; Ribavirin; Zanamivir

2016
Antiviral activity of SA-2 against influenza A virus in vitro/vivo and its inhibition of RNA polymerase.
    Antiviral research, 2016, Volume: 127

    Topics: A549 Cells; Acute Lung Injury; Animals; Antiviral Agents; Benzoates; DNA-Directed RNA Polymerases; Dogs; Drug Evaluation, Preclinical; Drug Resistance, Viral; HEK293 Cells; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Madin Darby Canine Kidney Cells; Male; Mice; Mice, Inbred ICR; Orthomyxoviridae Infections; Oseltamivir; Ribavirin; Virus Replication

2016
SARS-CoV-2 persisted in lung tissue despite disappearance in other clinical samples.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2020, Volume: 26, Issue:10

    Topics: Aged; Antiviral Agents; Betacoronavirus; Blood Loss, Surgical; Blood Volume; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID-19 Testing; Extracorporeal Membrane Oxygenation; Fatal Outcome; Humans; Hypertension; Lung; Lung Transplantation; Male; Oseltamivir; Pandemics; Pneumonia, Viral; Respiration, Artificial; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; SARS-CoV-2; Severity of Illness Index; Tomography, X-Ray Computed; Virus Shedding

2020
In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses.
    Viruses, 2020, 10-08, Volume: 12, Issue:10

    Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Cell Line; Dibenzothiepins; Dogs; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Guanidines; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Morpholines; Neuraminidase; Nucleic Acid Synthesis Inhibitors; Orthomyxoviridae Infections; Oseltamivir; Pyrazines; Pyridones; Ribavirin; Triazines; Viral Proteins; Virus Replication; Zanamivir

2020
Anti-influenza virus activity of the REV-ERBα agonist SR9009 and related analogues.
    Antiviral research, 2022, Volume: 207

    Topics: Adamantane; Antiviral Agents; ARNTL Transcription Factors; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Interferons; Oseltamivir; Pyrrolidines; Ribavirin; Thiophenes

2022