Page last updated: 2024-08-24

oseltamivir and clopidogrel

oseltamivir has been researched along with clopidogrel in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Mazzolari, A; Pedretti, A; Testa, B; Vistoli, G1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Akhlaghi, F; Black, C; LeCluyse, EL; Shi, D; Yan, B; Yang, D; Yang, J; You, L1
Shi, D; Song, X; Yan, B; Yang, D; Yang, J1
Fowler, S; Hoffmann, G; Lennon, SM; Rayner, CR1
Matsunami, N; Nagano, Y; Ono, H; Sugiyama, S; Tanabe, M; Yamamoto, S1
Malmioja, K; Peura, L; Rautio, J1
Antoku, Y; Hanatani, T; Hori, K; Kawakami, J; Kimura, M; Nakashima, N; Ohe, K; Sai, K; Saito, Y; Segawa, K; Tohkin, M; Yokoi, H1
Merali, Z; Paré, G; Ross, S1
Akhilesh, R; Chow, VTK; Malayer, JR; Maram, P; Pulavendran, S; Rudd, JM; Teluguakula, N; Thomas, PG1
Markowitz, JS; Qian, Y1

Reviews

4 review(s) available for oseltamivir and clopidogrel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Prodrug technology in the development of medicinal agents].
    Duodecim; laaketieteellinen aikakauskirja, 2011, Volume: 127, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Delivery Systems; Drug Design; Humans; Lansoprazole; Oseltamivir; Prodrugs; Simvastatin; Ticlopidine

2011
The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect.
    Drug metabolism and drug interactions, 2014, Volume: 29, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Aspirin; Benzimidazoles; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Central Nervous System Stimulants; Clopidogrel; Dabigatran; Factor Xa Inhibitors; Genotype; Humans; Imidazolidines; Irinotecan; Isoenzymes; Methylphenidate; Oseltamivir; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Pyridines; Ticlopidine

2014
Natural Products as Modulators of CES1 Activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:10

    Topics: Administration, Intravenous; Administration, Oral; Biological Products; Carboxylic Ester Hydrolases; Clopidogrel; Drug Evaluation, Preclinical; Drug Interactions; Humans; Methylphenidate; Oseltamivir

2020

Other Studies

7 other study(ies) available for oseltamivir and clopidogrel

ArticleYear
In silico prediction of human carboxylesterase-1 (hCES1) metabolism combining docking analyses and MD simulations.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Computer Simulation; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Substrate Specificity

2010
Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Antiviral Agents; Carboxylic Ester Hydrolases; Cell Line; Cell Survival; Clopidogrel; Drug Interactions; Humans; Hydrolysis; Mass Spectrometry; Microsomes; Mutagenesis, Site-Directed; Oseltamivir; Platelet Aggregation Inhibitors; Ticlopidine; Transfection

2006
Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2.
    Molecular pharmacology, 2007, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antiviral Agents; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Clopidogrel; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Interleukin-6; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oseltamivir; Platelet Aggregation Inhibitors; RNA, Messenger; Ticlopidine

2007
Comments on "Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel".
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1

    Topics: Antiviral Agents; Biotransformation; Carboxylic Ester Hydrolases; Clopidogrel; Drug Interactions; Humans; Oseltamivir; Platelet Aggregation Inhibitors; Ticlopidine

2007
Oseltamivir, an anti-influenza virus drug, produces hypothermia in mice.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Area Under Curve; Body Temperature; Clopidogrel; Diclofenac; Dose-Response Relationship, Drug; Hypothermia; Male; Mice; Oseltamivir; Platelet Aggregation Inhibitors; Ticlopidine; Zanamivir

2008
Evaluation of two Japanese regulatory actions using medical information databases: a 'Dear Doctor' letter to restrict oseltamivir use in teenagers, and label change caution against co-administration of omeprazole with clopidogrel.
    Journal of clinical pharmacy and therapeutics, 2014, Volume: 39, Issue:4

    Topics: Adolescent; Age Factors; Antiviral Agents; Child; Clopidogrel; Databases, Factual; Drug and Narcotic Control; Drug Interactions; Humans; Interrupted Time Series Analysis; Japan; Omeprazole; Oseltamivir; Pharmacovigilance; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Proton Pump Inhibitors; Regression Analysis; Ticlopidine; Young Adult

2014
Combination Therapy Targeting Platelet Activation and Virus Replication Protects Mice against Lethal Influenza Pneumonia.
    American journal of respiratory cell and molecular biology, 2019, Volume: 61, Issue:6

    Topics: Animals; Clopidogrel; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Extracellular Traps; Female; Histones; Influenza A Virus, H1N1 Subtype; Lung; Mice; Neutrophils; Orthomyxoviridae Infections; Oseltamivir; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Pneumonia, Viral; Thrombophilia; Virus Replication

2019