Page last updated: 2024-08-24

oseltamivir and 2-deoxy-2,3-dehydro-n-acetylneuraminic acid

oseltamivir has been researched along with 2-deoxy-2,3-dehydro-n-acetylneuraminic acid in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Chen, XG; Chen, YL; Hu, ZD; Liu, MC; Lü, WJ; Luan, F; Ma, WP; Zhang, XY1
Hata, K; Hirai, G; Koseki, K; Miyagi, T; Moriya, S; Sodeoka, M; Suzuki, Y; von Itzstein, M; Yamaguchi, K; Yingsakmongkon, S1
Chavas, LM; Dyason, JC; Fusi, P; Kato, R; Mann, MC; McKimm-Breschkin, J; Monti, E; Suzuki, N; Tettamanti, G; Thomson, RJ; Tringali, C; Venerando, B; von Itzstein, M; Wakatsuki, S1
Albohy, A; Cairo, CW; Sandbhor, M; Zou, Y1
Cairo, CW; Guo, T; Hunter, CD; Richards, MR1
Bourguet, E; Figurska, S; Fra Czek, MM1
Aljohani, MA; Keil, JM; Rafn, GR; Sahebjam-Atabaki, R; Sun, XL; Turan, IM1
Bethell, RC; Blick, TJ; Colman, PM; Hart, GJ; McDonald, M; McKimm-Breschkin, JL; Sahasrabudhe, A; Varghese, JN1
Chou, KC; Du, QS; Sun, H; Wei, DQ1
Barrett, S; McKimm-Breschkin, JL; Mohr, PG; Schmidt, PM1
Liu, GJ; Wang, B; Wang, S; Xing, GW; Yang, X; Zhang, Y1

Reviews

2 review(s) available for oseltamivir and 2-deoxy-2,3-dehydro-n-acetylneuraminic acid

ArticleYear
Human Neuraminidases: Structures and Stereoselective Inhibitors.
    Journal of medicinal chemistry, 2022, 02-24, Volume: 65, Issue:4

    Topics: Amino Acid Sequence; Enzyme Inhibitors; Humans; Models, Molecular; Neuraminidase; Stereoisomerism; Structure-Activity Relationship

2022
Sialidase Inhibitors with Different Mechanisms.
    Journal of medicinal chemistry, 2022, 10-27, Volume: 65, Issue:20

    Topics: Antiviral Agents; Biological Products; Enzyme Inhibitors; Humans; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Sialic Acids; Zanamivir

2022

Other Studies

9 other study(ies) available for oseltamivir and 2-deoxy-2,3-dehydro-n-acetylneuraminic acid

ArticleYear
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Enzyme Inhibitors; Linear Models; Models, Biological; Neuraminidase; Quantitative Structure-Activity Relationship

2008
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Antiviral Agents; Cell Line; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Neuraminidase; Orthomyxoviridae; Oseltamivir; Recombinant Proteins; RNA, Messenger; Zanamivir

2008
Complexity in influenza virus targeted drug design: interaction with human sialidases.
    Journal of medicinal chemistry, 2010, Apr-08, Volume: 53, Issue:7

    Topics: Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Models, Molecular; Molecular Conformation; Neuraminidase; Orthomyxoviridae

2010
Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Alkynes; Azides; Binding Sites; Catalysis; Computer Simulation; Copper; Humans; N-Acetylneuraminic Acid; Neuraminidase; Structure-Activity Relationship; Triazoles

2010
Molecular dynamics simulations of viral neuraminidase inhibitors with the human neuraminidase enzymes: Insights into isoenzyme selectivity.
    Bioorganic & medicinal chemistry, 2018, 10-15, Volume: 26, Issue:19

    Topics: Amino Acid Sequence; Antiviral Agents; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoenzymes; Kinetics; Molecular Dynamics Simulation; Neuraminidase; Sequence Alignment; Viral Proteins; Zanamivir

2018
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors.
    Journal of virology, 1998, Volume: 72, Issue:3

    Topics: Acetamides; Adsorption; Animals; Binding Sites; Birds; Cell Line; Conserved Sequence; Dogs; Drug Resistance, Microbial; Enzyme Inhibitors; Guanidines; Heating; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Kinetics; Molecular Structure; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Phenotype; Pyrans; Sialic Acids; Substrate Specificity; Viral Plaque Assay; Virus Replication; Zanamivir

1998
Insights from modeling the 3D structure of H5N1 influenza virus neuraminidase and its binding interactions with ligands.
    Biochemical and biophysical research communications, 2006, Jun-09, Volume: 344, Issue:3

    Topics: Acetamides; Binding Sites; Computer Simulation; Enzyme Activation; Guanidines; Influenza A Virus, H5N1 Subtype; Models, Chemical; Models, Molecular; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Protein Binding; Protein Conformation; Pyrans; Sequence Analysis, Protein; Sialic Acids; Structure-Activity Relationship; Zanamivir

2006
Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Acids, Carbocyclic; Binding, Competitive; Cyclopentanes; Enzyme Assays; Enzyme Inhibitors; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Inhibitory Concentration 50; Kinetics; Mutation; N-Acetylneuraminic Acid; Neuraminidase; Orthomyxoviridae; Oseltamivir; Protein Binding; Substrate Specificity; Time Factors; Viral Proteins; Zanamivir

2011
A tetravalent sialic acid-coated tetraphenylethene luminogen with aggregation-induced emission characteristics: design, synthesis and application for sialidase activity assay, high-throughput screening of sialidase inhibitors and diagnosis of bacterial va
    Chemical communications (Cambridge, England), 2018, Sep-20, Volume: 54, Issue:76

    Topics: Adult; Clostridium perfringens; Enzyme Inhibitors; Female; Fluorescence; Fluorescent Dyes; Fluorometry; High-Throughput Screening Assays; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Limit of Detection; Middle Aged; N-Acetylneuraminic Acid; Neuraminidase; Oseltamivir; Sialic Acids; Stilbenes; Vaginosis, Bacterial; Vibrio cholerae; Young Adult; Zanamivir

2018