Compounds > orphenadrine

orphenadrine and metyrapone

orphenadrine has been researched along with metyrapone in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fantel, AG; Juchau, MR; Lee, QH1
Brain, EG; Drewes, P; Gustafsson, K; Waxman, DJ; Yu, LJ1

Reviews

1 review(s) available for orphenadrine and metyrapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for orphenadrine and metyrapone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Human embryonic cytochrome P450S: phenoxazone ethers as probes for expression of functional isoforms during organogenesis.
    Biochemical pharmacology, 1991, Nov-27, Volume: 42, Issue:12

    Topics: Antibodies, Monoclonal; Benzoflavones; Biotransformation; Carbon Monoxide; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Ethers; Humans; Isoenzymes; Metyrapone; Morphogenesis; Orphenadrine; Oxazines; Oxidoreductases; Xenobiotics

1991
Modulation of P450-dependent ifosfamide pharmacokinetics: a better understanding of drug activation in vivo.
    British journal of cancer, 1998, Volume: 77, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Biotransformation; Cytochrome P-450 Enzyme System; Dexamethasone; Ifosfamide; Male; Metyrapone; Microsomes, Liver; Orphenadrine; Phenobarbital; Rats; Rats, Inbred F344; Troleandomycin

1998