orphenadrine and diclofenac

orphenadrine has been researched along with diclofenac in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's2 (7.69)18.2507
2000's5 (19.23)29.6817
2010's6 (23.08)24.3611
2020's12 (46.15)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Flygare, U; Hurme, J; Seuri, M; Wuolijoki, E1
Aglas, F; Rainer, F; Uitz, E; Wurm, A1
Aglas, F; Chlud, K; Fruhwald, FM1
Kostál, R; Lopourová, M; Málek, J; Nedĕlová, I; Stefan, M1
Eggenreich, U; Gschanes, A; Reitmeir, P; Schaffler, K1
Borsodi, M; Darvas, K; Nagy, E1
Blasl, J; Gombotz, H; Herzer, G; Lochner, R; Sigl, R; Trimmel, H1
Park, JS; Seo, KW; Shin, JH; Tahk, SJ1
El-Adl, SM; Mattar, AA; Sebaiy, MM1
Butranova, OI; Putsman, GA; Zyryanov, SK1
Amelin, AV; Gotovchikov, AA; Tereshchenko, NM1
Hassanzadeh, H; Mischak, I; Payer, M; Sandner-Kiesling, A; Schanbacher, M; Sendlhofer, G; Tomic, J; Wallner, J; Zemann, W; Zrnc, TA1
Eremenko, AA; Koshek, EA; Ryabova, DV; Sorokina, LS1
Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V1
Correia, AT; Guimarães, LL; Roveri, V; Toma, W1
Eremenko, AA; Ryabova, DV; Sorokina, LS; Urbanov, AV1
Haider, T; Höbart, P; Kimberger, O; Knolle, E; Thüringer, K; Zeiner, S; Zotti, O1
Fritsch, G; Oberladstaetter, D; Prossinger, H; Steltzer, H; Zeller, C1
Kiselev, DV; Lavrukhin, VV1
Gukalov, AA; Klypa, TV; Mandel', IA; Minets, AI1

Reviews

1 review(s) available for orphenadrine and diclofenac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for orphenadrine and diclofenac

ArticleYear
Relief of spasm with diclofenac.
    Clinical rheumatology, 1988, Volume: 7, Issue:1

    Topics: Clinical Trials as Topic; Diclofenac; Humans; Orphenadrine; Spasm

1988
[Diclofenac 75mg. and 30 mg. orfenadine (Neodolpasse) versus placebo and piroxicam in postoperative analgesia after arthroscopy].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2004, Volume: 71, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Combinations; Humans; Infusions, Intravenous; Knee Joint; Muscle Relaxants, Central; Orphenadrine; Pain Measurement; Pain, Postoperative; Piroxicam

2004
Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials fro
    Drugs in R&D, 2005, Volume: 6, Issue:4

    Topics: Adult; Analgesics; Capsaicin; Cross-Over Studies; Diclofenac; Double-Blind Method; Drug Combinations; Evoked Potentials, Somatosensory; Female; Humans; Hyperalgesia; Infusions, Intravenous; Lasers; Male; Middle Aged; Orphenadrine; Pain

2005
[Diclofenac/orphenadrine as a combined analgetic in post-operative relief of pain].
    Orvosi hetilap, 2008, Sep-28, Volume: 149, Issue:39

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Narcotics; Orphenadrine; Pain Measurement; Pain, Postoperative; Prospective Studies; Statistics, Nonparametric; Tramadol; Treatment Outcome; Young Adult

2008
Opiate sparing effect of fixed combination of diclophenac and orphenadrine after unilateral total hip arthroplasty: A double-blind, randomized, placebo-controlled, multi-centre clinical trial.
    Wiener medizinische Wochenschrift (1946), 2010, Volume: 160, Issue:19-20

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Arthroplasty, Replacement, Hip; Diclofenac; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Narcotics; Orphenadrine; Pain Measurement; Pain, Postoperative; Prospective Studies

2010
Intravenous ibuprofen versus diclofenac plus orphenadrine in orthognathic surgery: a prospective, randomized, double-blind, controlled clinical study.
    Clinical oral investigations, 2022, Volume: 26, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Orphenadrine; Orthognathic Surgery; Pain, Postoperative; Pirinitramide; Prospective Studies; Young Adult

2022
[Analgesic and opioid-sparing effects of a fixed combination of diclofenac and orphenadrine in the early postoperative period in cardiac surgery patients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:10

    Topics: Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Diclofenac; Humans; Morphine; Orphenadrine; Pain, Postoperative; Postoperative Period; Prospective Studies

2022
Intravenous diclofenac and orphenadrine for the treatment of postoperative pain after remifentanil-based anesthesia : A double-blinded, randomized, placebo-controlled study.
    Wiener klinische Wochenschrift, 2023, Volume: 135, Issue:3-4

    Topics: Analgesics; Analgesics, Opioid; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Hydromorphone; Orphenadrine; Pain, Postoperative; Remifentanil

2023

Other Studies

17 other study(ies) available for orphenadrine and diclofenac

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Diclofenac/orphenadrine infusion therapy in patients with active arthrosis].
    Wiener medizinische Wochenschrift (1946), 1998, Volume: 148, Issue:7

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Administration Schedule; Drug Combinations; Female; Humans; Infusions, Intravenous; Knee Joint; Male; Middle Aged; Muscle Relaxants, Central; Orphenadrine; Osteoarthritis; Osteoarthritis, Hip; Pain Measurement; Prospective Studies; Radiography; Treatment Outcome

1998
[Results of efficacy study with diclofenac/orphenadrine infusions in patients with musculoskeletal diseases and functional disorders].
    Acta medica Austriaca, 1998, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Muscle Relaxants, Central; Orphenadrine; Pain Measurement; Practice Guidelines as Topic; Product Surveillance, Postmarketing; Rheumatic Diseases

1998
A Case of Acute Myocardial Infarction Induced by Selective Cyclooxygenase-2 Inhibitor.
    Chinese medical journal, 2017, May-05, Volume: 130, Issue:9

    Topics: Calcium Channel Blockers; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Male; Middle Aged; Myocardial Infarction; Nitrates; Nitroglycerin; Orphenadrine

2017
Different techniques for overlapped UV spectra resolution of some co-administered drugs with paracetamol in their combined pharmaceutical dosage forms.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Jan-05, Volume: 224

    Topics: Acetaminophen; Caffeine; Diclofenac; Linear Models; Models, Chemical; Orphenadrine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2020
[The efficacy of the combination of diclofenac and orphenadrine in the treatment of dorsalgia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2021, Volume: 121, Issue:5

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Moscow; Orphenadrine

2021
[Clinical experience with the use of a fixed combination of diclofenac and orphenadrine in the treatment of acute pain syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2021, Volume: 121, Issue:8

    Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Orphenadrine; Pain Measurement

2021
[Efficiency and safety of a fixed combination of Orphenadrine and Diclofenac for postoperative analgesia in cardiac surgery patients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:2

    Topics: Analgesia, Patient-Controlled; Cardiac Surgical Procedures; Diclofenac; Humans; Orphenadrine; Pain, Postoperative; Retrospective Studies

2022
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:42

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical

2022
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:59

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical

2022
Artificial intelligence algorithms predict the efficacy of analgesic cocktails prescribed after orthopedic surgery.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Analgesics; Artificial Intelligence; Bayes Theorem; Diclofenac; Humans; Hydromorphone; Orphenadrine; Orthopedic Procedures; Pain, Postoperative

2023
[The use of a fixed combination of diclofenac and orphenadrine in the treatment of acute pain syndrome in patients with discogenic lumbosacral radiculopathy and lumboischialgia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2023, Volume: 123, Issue:3

    Topics: Acute Pain; Back Pain; Diclofenac; Humans; Orphenadrine; Radiculopathy

2023
[The use of a fixed combination of diclofenac and orphenadrine for postoperative pain relief in orthopedic patients].
    Khirurgiia, 2023, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Morphine; Orphenadrine; Pain, Postoperative; Prospective Studies

2023