orphenadrine and amitriptyline

orphenadrine has been researched along with amitriptyline in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (57.69)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (19.23)	29.6817
2010's	5 (19.23)	24.3611
2020's	1 (3.85)	2.80

Authors

Authors	Studies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Bailey, AM; Paulsen, IT; Piddock, LJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Sen, S; Sinha, N	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
How, J; Strachan, RW	1
Ciancio, SG	1
Berry, WK; Davies, DR; Gordon, JJ	1
Chandra, O; Dhawan, KN; Gupta, GP; Saxena, RC	1
Dresse, A; Van Dorsser, W	1
Blomquist, M; Bonnichsen, R; Fri, CG; Mårde, Y; Ryhage, R	1
Florio, V; Longo, VG	1
Johnson, J; Milner, G	1
GILLINGHAM, FJ; KALYANARAMAN, S	1
ROTH, M	1
CURRAN, DA; LANCE, JW	1
TAIT, AC; TODRICK, A; YATES, CM	1
BAEUMLER, J; OBERSTEG, JI	1
BAEUMLER, J; IMOBERSTEG, J	1
Cotroneo, A; De Fazio, P; De Fazio, S; De Sarro, G; Gallelli, L; Gareri, P; Lacava, R	1
Burger, J; Coelho, C; Elgoyhen, AB; Figueiredo, R; Frank, E; Landgrebe, M; Langguth, B; Schecklmann, M	1
Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM	1

Reviews

1 review(s) available for orphenadrine and amitriptyline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for orphenadrine and amitriptyline

Article	Year
Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study. Audiology & neuro-otology, 2012, Volume: 17, Issue:3 Topics: Adult; Aged; Amitriptyline; Clonidine; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Orphenadrine; Pilot Projects; Propiophenones; Severity of Illness Index; Tinnitus; Treatment Outcome	2012

Other Studies

24 other study(ies) available for orphenadrine and amitriptyline

Article	Year
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Anti-Bacterial Agents; Antipsychotic Agents; Bacterial Proteins; Base Sequence; Chlorpromazine; DNA Primers; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Synergism; Ethidium; Gene Expression; Genes, Bacterial; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Oligonucleotide Array Sequence Analysis; Phenothiazines; Salmonella typhimurium; Trans-Activators	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Acute dilatation of stomach as late complication of drug overdose. British medical journal, 1976, Mar-06, Volume: 1, Issue:6009 Topics: Acute Disease; Adolescent; Amitriptyline; Anti-Anxiety Agents; Female; Flurazepam; Gastric Dilatation; Humans; Orphenadrine	1976
Drugs in dentistry. Muscle relaxants. Dental management, 1985, Volume: 25, Issue:12 Topics: Amitriptyline; Carisoprodol; Humans; Methocarbamol; Muscle Relaxants, Central; Orphenadrine	1985
Protection of animals against soman (1,2,2-trimethylpropyl methylphosphono-fluoridate) by pretreatment with some other organophosphorus compounds, followed by oxime and atropine. Biochemical pharmacology, 1971, Volume: 20, Issue:1 Topics: Amitriptyline; Animals; Atropine; Bromides; Carbamates; Cholinesterase Inhibitors; Diphosphates; Drug Antagonism; Female; Fluorine; Guinea Pigs; Hydroxamic Acids; Isoflurophate; Lethal Dose 50; Nitrates; Nitrophenols; Nitroso Compounds; Organophosphonates; Organophosphorus Compounds; Orphenadrine; Oximes; Parasympatholytics; Physostigmine; Poisoning; Pyridinium Compounds; Rabbits; Rats; Salicylates; Scopolamine; Species Specificity; Sulfonic Acids; Sulfuric Acids; Thiazoles; Time Factors	1971
Assessment of anti-reserpine and anti-apomorphine activities of some psychic energizers in pigeons. Psychopharmacologia, 1969, Volume: 15, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Columbidae; Deanol; Desipramine; Female; Hydrazines; Imipramine; Male; Opipramol; Orphenadrine; Reserpine; Vomiting	1969
[Comparative effects of various antidepressants on the response to noradrenaline of the deferent canal and the arterial pressure, and the response to 5-hydroxytryptamine of the rat uterus]. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Clomipramine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Orphenadrine; Quinuclidines; Rats; Serotonin; Uterus; Vas Deferens	1974
Gas chromatography-mass spectrometry in forensic chemistry for identification of substances isolated from tissue. Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1971, Volume: 69, Issue:1 Topics: Amitriptyline; Chromatography, Gas; Forensic Medicine; Mass Spectrometry; Meperidine; Methaqualone; Nortriptyline; Orphenadrine; Phenethylamines; Spectrum Analysis	1971
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice. Physiology & behavior, 1971, Volume: 6, Issue:4 Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl	1971
Hiccup. British medical journal, 1971, May-01, Volume: 2, Issue:5756 Topics: Amides; Amitriptyline; Benzoates; Catheterization; Chlorpromazine; Digestive System; Hiccup; Humans; Orphenadrine; Pharynx; Respiratory System	1971
Psychiatric complications of amphetamine substances. Acta psychiatrica Scandinavica, 1966, Volume: 42, Issue:3 Topics: Adolescent; Adult; Amitriptyline; Amphetamine; Chlordiazepoxide; Depression; Ephedrine; Female; Hallucinations; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Orphenadrine; Paranoid Disorders; Promethazine; Psychotic Disorders; Schizophrenia; Substance-Related Disorders	1966
PARKINSON'S DISEASE. Physiotherapy, 1963, Dec-10, Volume: 49 Topics: Amitriptyline; Dextroamphetamine; Humans; Imipramine; Muscle Relaxants, Central; Neurosurgery; Orphenadrine; Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Pathology; Stereotaxic Techniques; Trihexyphenidyl	1963
DEPRESSIVE AND MANIC PSYCHOSES AND ALLIED DISORDERS. Current medicine and drugs, 1964, Volume: 4, Issue:8 Topics: Adolescent; Amitriptyline; Antidepressive Agents; Barbiturates; Bipolar Disorder; Depression; Electroconvulsive Therapy; Geriatrics; Haloperidol; Humans; Imipramine; Lithium; Mental Disorders; Middle Aged; Orphenadrine; Psychotherapy; Psychotic Disorders	1964
TREATMENT OF CHRONIC TENSION HEADACHE. Lancet (London, England), 1964, Jun-06, Volume: 1, Issue:7345 Topics: Amitriptyline; Amobarbital; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diazepam; Ergot Alkaloids; Ergotamine; Headache; Headache Disorders; Imipramine; Methysergide; Orphenadrine; Phenobarbital; Placebos; Psychosomatic Medicine; Selective Serotonin Reuptake Inhibitors; Serotonin; Tension-Type Headache; Tranquilizing Agents; Tranylcypromine; Trifluoperazine; Vasodilator Agents	1964
EFFECT OF IMIPRAMINE AND SOME ANALOGUES ON THE UPTAKE OF 5-HYDROXYTRYPTAMINE BY HUMAN BLOOD PLATELETS IN VITRO. The Journal of pharmacy and pharmacology, 1964, Volume: 16 Topics: Amitriptyline; Antidepressive Agents; Blood Platelets; Chlorpromazine; Desipramine; Humans; Imipramine; In Vitro Techniques; Metabolism; Orphenadrine; Pharmacology; Research; Serotonin	1964
[ON SUICIDE WIH PSYCHOPHARMACOLOGICAL AGENTS]. Munchener medizinische Wochenschrift (1950), 1964, May-22, Volume: 106 Topics: Amitriptyline; Diazepam; Orphenadrine; Reserpine; Suicide; Switzerland; Toxicology	1964
[FATAL CASES OF POISONING WITH PSYCHOPHARMACEUTICALS]. Beitrage zur gerichtlichen Medizin, 1965, Volume: 23 Topics: Amitriptyline; Chromatography; Orphenadrine; Poisoning; Psychotropic Drugs; Toxicology	1965
Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1 Topics: Acute Disease; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Antipsychotic Agents; Cholinergic Antagonists; Delirium; Depressive Disorder, Major; Drug Therapy, Combination; GABA Modulators; Haloperidol; Humans; Lorazepam; Male; Orphenadrine	2007
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. Neurology, 2022, 09-27, Volume: 99, Issue:13 Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort Studies; Humans; Hydrocodone; Methocarbamol; Narcotic Antagonists; Neuromuscular Agents; Opiate Overdose; Orphenadrine; Oxycodone; Prescriptions; Sepsis; Substance-Related Disorders	2022