orphenadrine and amantadine

orphenadrine has been researched along with amantadine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hecht, P; Kornhuber, J; Koutsilieri, E; Kroemer, RT; Liedl, KR; Riederer, P1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mindham, RH1
Postma, JU; Van Tilburg, W1
Marsden, CD1
Parkenberg, H1
Costall, B; Naylor, RJ1
Anstee, BH; Gaind, R; Mindham, RH; Rimmer, L1
Florio, V; Longo, VG1
Wheatley, D1
Balster, RL; Harvey, SA; Nicholson, KL; Wiley, JL1

Reviews

2 review(s) available for orphenadrine and amantadine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advances in the management of parkinson's disease.
    Scottish medical journal, 1976, Volume: 21, Issue:3

    Topics: Amantadine; Anesthesia; Humans; Levodopa; Orphenadrine; Parasympatholytics; Parkinson Disease; Social Adjustment; Trihexyphenidyl

1976

Trials

2 trial(s) available for orphenadrine and amantadine

ArticleYear
Assessment of drugs in schizophrenia. Asessment of drug-induced extrapyramidal reactions and of drugs given for their control.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:3 Suppl 2

    Topics: Amantadine; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as Topic; Drug Evaluation; Fluphenazine; Humans; Orphenadrine; Parkinson Disease, Secondary; Piribedil; Procyclidine

1976
Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism.
    Psychological medicine, 1972, Volume: 2, Issue:4

    Topics: Affect; Amantadine; Basal Ganglia Diseases; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Fluphenazine; Humans; Male; Orphenadrine; Parkinson Disease; Parkinson Disease, Secondary; Placebos; Schizophrenia

1972

Other Studies

9 other study(ies) available for orphenadrine and amantadine

ArticleYear
Quantitative analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Binding Sites; Excitatory Amino Acid Antagonists; Humans; Molecular Structure; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Visual hallucinations and delirium during treatment with amantadine (Symmetrel).
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:5

    Topics: Aged; Amantadine; Benztropine; Biperiden; Delirium; Drug Eruptions; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Orphenadrine; Parkinson Disease

1975
[Treatment of parkinsonism].
    Ugeskrift for laeger, 1976, Apr-26, Volume: 138, Issue:18

    Topics: Amantadine; Benztropine; Biperiden; Humans; Levodopa; Orphenadrine; Parkinson Disease; Procyclidine; Trihexyphenidyl

1976
The relationship between the inhibition of dopamine uptake and the enhancement of amphetamine stereotypy.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Aug-15, Volume: 10, Issue:16

    Topics: Amantadine; Amphetamine; Animals; Behavior, Animal; Chlorpheniramine; Dopamine; Dopamine Antagonists; Drug Synergism; Histamine H1 Antagonists; Injections, Intraperitoneal; Male; Orphenadrine; Parasympatholytics; Parkinson Disease; Piperidines; Rats; Trihexyphenidyl

1971
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
    Physiology & behavior, 1971, Volume: 6, Issue:4

    Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl

1971
Combined treatment in Parkinson's disease.
    The Practitioner, 1983, Volume: 227, Issue:1377

    Topics: Aged; Amantadine; Antiparkinson Agents; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Orphenadrine; Parkinson Disease

1983
Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats.
    Psychopharmacology, 2003, Volume: 165, Issue:4

    Topics: Acoustic Stimulation; Adrenergic Uptake Inhibitors; Alanine; Amantadine; Animals; Binding Sites; Desipramine; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ibogaine; Loudness Perception; Male; Memantine; Muscarinic Antagonists; Neural Inhibition; Orphenadrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Selective Serotonin Reuptake Inhibitors

2003