orotidine and uridine
orotidine has been researched along with uridine in 51 studies
Research
Studies (51)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (41.18) | 18.7374 |
| 1990's | 16 (31.37) | 18.2507 |
| 2000's | 5 (9.80) | 29.6817 |
| 2010's | 6 (11.76) | 24.3611 |
| 2020's | 3 (5.88) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ferris, JP; Joshi, PC | 1 |
| Schretlen, ED; Tax, WJ; Veerkamp, JH | 1 |
| Cha, S; Janeway, CM | 1 |
| Bordugo, A; Burlina, AB; Dionisi-Vici, C; Ferrari, V; Tuchman, M; Zacchello, F | 1 |
| Bennett, JE; Edman, JC; Kwon-Chung, KJ; Varma, A | 1 |
| Katoh, T; Kibe, T; Kidouchi, K; Nakamura, C; Ohba, S; Wada, Y | 1 |
| Cameron, JS; Davies, PM; Reiter, S; Simmonds, HA | 1 |
| Tuchman, M | 1 |
| Brusilow, SW; Finkelstein, JE; Hauser, ER; Valle, D | 1 |
| Fenton, WA; Horwich, AL | 1 |
| Brusilow, SW; Hauser, E | 1 |
| Heick, HM; Korneluk, RG; MacKenzie, AE; MacLeod, HL | 1 |
| Kamatani, N; Kitamura, M; Kojima, T; Nishina, T; Nishioka, K | 1 |
| Lin, RC; Snodgrass, PJ | 1 |
| Gröbner, W; Löffler, W; Reiter, S; Zöllner, N | 1 |
| Miyake, H; Nakano, K; Okada, J | 1 |
| Arakawa, S; Hashimoto, M; Matsunaga, Y; Miyazaki, H; Yoshida, K | 1 |
| Golovinsky, E; Spassova, M | 1 |
| Harris, ML; Oberholzer, VG | 1 |
| Fairbanks, LD; Krijt, J; Sebesta, I; Simmonds, HA | 1 |
| Davies, PM; Fairbanks, LD; Leonard, JV; Sebesta, I; Simmonds, HA | 1 |
| Daniewska-Michalska, D; Gellert, R; Kukulska, W; Motyl, T; Opechowska-Pacocha, E; Ostrowski, K; Podgurniak, M | 1 |
| Hariguchi, F; Hayashi, T; Kobayashi, N; Matsuno, T; Okada, Y; Okamoto, T | 2 |
| Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Lund, AE | 1 |
| Allen, JC; Bonham, JR; Downing, M; Duley, JA; Fairbanks, LD; Fensom, A; Guthrie, P; Land, JM; O'Neill, D; Rittey, C; Sharrard, M; Tanner, MS | 1 |
| Arranz, JA; Burlina, A; Climent, C; Riudor, E; Rodés, M; Roig, M; Rubio, V; Sentís, M | 1 |
| Arranz, JA; Burlina, AB; Riudor, E; Rodés, M; Rubio, V; Sentís, M | 1 |
| Egawa, H; Kikuta, H; Kobayashi, K; Nagasaka, H; Tanaka, K; Yorifuji, T | 1 |
| Chu, CK; el Kouni, MH; Naguib, FN; Song, GY | 1 |
| FOX, JJ; WEMPEN, I; YUNG, N | 1 |
| HANDSCHUMACHER, RE | 1 |
| HABERMANN, V | 1 |
| BLAIR, DG; POTTER, VR; STONE, JE | 1 |
| BONO, VH; LEWIS, M; WEISSMAN, S | 1 |
| FINK, RM; PYNADATH, TI | 1 |
| KAPOOR, M; WAYGOOD, ER | 1 |
| KORNBERG, A; LIEBERMAN, I; SIMMS, ES | 1 |
| DRELL, W; MICHELSON, AM; MITCHELL, HK | 1 |
| Sievers, A; Wolfenden, R | 1 |
| Bailey, CJ | 1 |
| Schramm, VL; Zhang, Y | 1 |
| Crandall, IE; Kain, KC; Kotra, LP; Pai, EF; Poduch, E; Purohit, MK; To, T; Wei, LW | 1 |
| Amyes, TL; Goryanova, B; Richard, JP; Spong, K | 1 |
| Kim, EK; Krishnamurthy, R | 1 |
| Kim, EK; Krishnamurthy, R; Martin, V | 1 |
| Bierau, J; Garbade, SF; Haas, D; Hauke, J; Hoffmann, GF; Klinke, G; Langhans, CD; Monostori, P; Okun, JG; Richter, S | 1 |
| Dubey, S; Jha, PC; Manhas, A | 1 |
| Cairns, TC; Sun, J; Wang, D; Zhang, L; Zhang, Z; Zheng, P; Zheng, X | 1 |
| Doria, A; Jobe, JM; Mendonca, C; Mitri, J; Monti, S; Moreno, LO; Morieri, ML; Niewczas, MA; Pennathur, S; Shah, HS; Tang, Y; Thacker, JB | 1 |
Reviews
2 review(s) available for orotidine and uridine
| Article | Year |
|---|---|
Analogs of pyrimidine and purine mononucleotide precursors as metabolic inhibitors.
Topics: Animals; Antimetabolites; Aspartic Acid; Imidazoles; Orotic Acid; Purine Nucleosides; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Triazoles; Uridine | 1981 |
Orotic aciduria and uridine monophosphate synthase: a reappraisal.
Topics: Adult; Anemia, Megaloblastic; Child; Child, Preschool; Humans; Infant; Kinetics; Metabolic Networks and Pathways; Models, Biological; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine-Pyrimidine Metabolism, Inborn Errors; Uridine; Uridine Monophosphate | 2009 |
Trials
3 trial(s) available for orotidine and uridine
| Article | Year |
|---|---|
Investigation for the characteristic anticoccidial activity of diclazuril in battery trials.
Topics: Animals; Chickens; Coccidiosis; Coccidiostats; Drug Interactions; Drug Resistance; Eimeria; Nitriles; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Triazines; Uracil; Uridine; Uridine Diphosphate Glucose; Uridine Diphosphate N-Acetylglucosamine | 1996 |
Effect of allopurinol and benzbromarone on the concentration of uridine in plasma.
Topics: Adult; Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Gout; Gout Suppressants; Humans; Male; Middle Aged; Purines; Pyrimidines; Time Factors; Uric Acid; Uricosuric Agents; Uridine; Xanthine Oxidase | 1997 |
Optimization of allopurinol challenge: sample purification, protein intake control, and the use of orotidine response as a discriminative variable improve performance of the test for diagnosing ornithine carbamoyltransferase deficiency.
Topics: Adolescent; Adult; Allopurinol; Child; Child, Preschool; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Female; Humans; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Proteins; ROC Curve; Sensitivity and Specificity; Uridine | 1999 |
Other Studies
46 other study(ies) available for orotidine and uridine
| Article | Year |
|---|---|
Chemical evolution from hydrogen cyanide: photochemical decarboxylation of orotic acid and orotate derivatives.
Topics: Decarboxylation; Hydrogen Cyanide; Orotic Acid; Photochemistry; Ribonucleotides; Uracil; Uridine; Uridine Monophosphate | 1978 |
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay.
Topics: Adolescent; Adult; Aging; Allopurinol; Breast Feeding; Child; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Pregnancy; Radioisotope Dilution Technique; Uridine | 1978 |
Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
Topics: Azauridine; Cells, Cultured; Lymphoma; Neoplasms, Experimental; Nucleotides; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine Nucleotides; Pyrimidine Nucleotides; Uridine | 1977 |
Allopurinol challenge test in children.
Topics: Adolescent; Aging; Allopurinol; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea; Uridine | 1992 |
Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-fluoroorotic acid medium.
Topics: Animals; Blotting, Southern; Cryptococcus neoformans; Culture Media; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA, Fungal; Humans; Mutation; Nucleic Acid Hybridization; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Restriction Mapping; Transformation, Genetic; Uracil; Uridine | 1992 |
Automated quantitative analysis for orotidine and uridine/thymine in urine by high-performance liquid chromatography with column switching.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Infant; Infant, Newborn; Male; Ornithine Carbamoyltransferase Deficiency Disease; Reference Values; Thymine; Uridine | 1991 |
Orotidine accumulation in human erythrocytes during allopurinol therapy: association with high urinary oxypurinol-7-riboside concentrations in renal failure and in the Lesch-Nyhan syndrome.
Topics: Allopurinol; Erythrocytes; Female; Humans; Kidney Failure, Chronic; Lesch-Nyhan Syndrome; Male; Nucleotides; Oxypurinol; Ribonucleosides; Uridine | 1991 |
Allopurinol-induced orotidinuria.
Topics: Allopurinol; Amino Acid Metabolism, Inborn Errors; Female; Genetic Carrier Screening; Humans; Ornithine Carbamoyltransferase Deficiency Disease; Uridine | 1990 |
Allopurinol-induced orotidinuria. A test for mutations at the ornithine carbamoyltransferase locus in women.
Topics: Adult; Allopurinol; Chromatography, High Pressure Liquid; Female; Genetic Carrier Screening; Heterozygote; Humans; Middle Aged; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uridine | 1990 |
Precarious balance of nitrogen metabolism in women with a urea-cycle defect.
Topics: Allopurinol; Ammonia; Coma; Female; Genetic Carrier Screening; Heterozygote; Humans; Nitrogen; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Pregnancy; Puerperal Disorders; Uridine | 1990 |
Simple method of measurement of orotic acid and orotidine in urine.
Topics: Chromatography, High Pressure Liquid; Humans; Nitrobenzoates; Orotic Acid; Spectrophotometry, Ultraviolet; Uridine | 1989 |
False positive results from the alanine loading test for ornithine carbamoyltransferase deficiency heterozygosity.
Topics: Adult; Alanine; Allopurinol; Ammonia; False Positive Reactions; Female; Genetic Carrier Screening; Humans; Infant, Newborn; Male; Ornithine Carbamoyltransferase Deficiency Disease; Pedigree; Uridine | 1989 |
Liquid chromatography with multichannel ultraviolet detection used for studying disorders of purine metabolism.
Topics: Adenine; Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Oxypurinol; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthine; Xanthines | 1987 |
Differing effects of arginine deficiency on the urea cycle enzymes of rat liver, cultured hepatocytes and hepatoma cells.
Topics: Ammonium Chloride; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Urea; Uridine; Valine | 1987 |
Urinary oxipurinol-1-riboside excretion and allopurinol-induced oroticaciduria.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Humans; Orotic Acid; Purines; Ribonucleosides; Uridine | 1986 |
Uracil derivatives. V. Syntheses and growth-inhibitory activity against L-1210 cells of 5-substituted 2'-deoxyuridines and orotidine derivatives.
Topics: Animals; Antineoplastic Agents; Cell Division; Cells, Cultured; Deoxyuridine; Leukemia L1210; Mice; Uridine | 1985 |
Simultaneous determination of plasma and urinary uric acid, xanthine, hypoxanthine, allopurinol, oxipurinol, orotic acid, orotidine and creatinine by high-performance liquid chromatography.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Creatinine; Gas Chromatography-Mass Spectrometry; Humans; Purines; Pyrimidines; Uridine | 1983 |
Conditions affecting the colorimetry of orotic acid and orotidine in urine.
Topics: Adult; Age Factors; Child; Child, Preschool; Colorimetry; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Infant; Infant, Newborn; Male; Orotic Acid; Uridine | 1980 |
The allopurinol loading test in detecting obligate heterozygotes for OCT deficiency.
Topics: Adolescent; Adult; Allopurinol; Chromatography, High Pressure Liquid; Female; Genetic Carrier Screening; Humans; Middle Aged; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uridine | 1994 |
The allopurinol loading test for identification of carriers for ornithine carbamoyl transferase deficiency: studies in a healthy control population and females at risk.
Topics: Adolescent; Adult; Allopurinol; Child; Female; Heterozygote; Humans; Middle Aged; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Predictive Value of Tests; Risk; Spectrophotometry, Ultraviolet; Uridine | 1994 |
Efficiency of hemodialysis of pyrimidine compounds in patients with chronic renal failure.
Topics: Adult; Aged; Allopurinol; Creatinine; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Orotic Acid; Pseudouridine; Pyrimidines; Renal Dialysis; Uric Acid; Uridine | 1993 |
Antagonistic effect of nucleic acid precursors on the anticoccidial activity of 6-azauracil.
Topics: Adenine; Adenosine; Animals; Chickens; Coccidiosis; Coccidiostats; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Eimeria; Food, Fortified; Male; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Uracil; Uridine | 1996 |
Quick cancer test developed.
Topics: Allopurinol; Antimetabolites; Biomarkers, Tumor; DNA; Humans; Neoplasms; Orotic Acid; Pyrimidines; Uridine | 1998 |
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.
Topics: Allopurinol; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolic Diseases; Mitochondria; Muscles; Orotic Acid; Predictive Value of Tests; Sensitivity and Specificity; Urea; Uridine | 1999 |
Influence of dose and age on the response of the allopurinol test for ornithine carbamoyltransferase deficiency in control infants.
Topics: Adolescent; Adult; Age Factors; Allopurinol; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uridine | 2000 |
Successful living-donor liver transplantation from an asymptomatic carrier mother in ornithine transcarbamylase deficiency.
Topics: Adult; Amino Acids; Child; Female; Heterozygote; Humans; Liver Transplantation; Living Donors; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Treatment Outcome; Uridine | 2001 |
Synthesis of carbocyclic orotidine analogs as potential orotidine decarboxylase inhibitors.
Topics: Acids, Carbocyclic; Animals; Biochemistry; Enzyme Inhibitors; Female; Humans; Liver; Mice; Mice, Inbred Strains; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Structure-Activity Relationship; Uridine | 2001 |
Spectrophotometric studies of nucleic acid derivatives and related compounds as a function of pH. IV. On the structure of orotidine. A study of N-methylated orotic acids.
Topics: Nucleic Acids; Nucleotides; Orotic Acid; Spectrophotometry; Uridine | 1957 |
Bacterial preparation of orotidine-5'-phosphate and uridine-5'-phosphate.
Topics: Biochemical Phenomena; Escherichia coli; Nucleosides; Nucleotides; Phosphates; Uridine | 1958 |
Elimination by the urine of orotic acid and orotidine in man after application of 6-azauracil.
Topics: Biological Transport; Body Fluids; Humans; Male; Nucleosides; Nucleotides; Orotic Acid; Uracil; Uridine | 1960 |
Formation of orotidine 5'-phosphate by enzymes from rat liver.
Topics: Liver; Nucleosides; Nucleotides; Phosphates; Uridine | 1960 |
METABOLIC INERTNESS OF OROTIDINE IN MAN AND THE RAT.
Topics: Body Fluids; Carbon Isotopes; Creatine; Creatinine; Kidney Function Tests; Leukemia; Nucleosides; Rats; Research; Uracil Nucleotides; Uridine; Urine | 1963 |
ENZYMIC PREPARATION OF RADIOACTIVE OROTIDINE 5'-PHOSPHATE.
Topics: Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Liver; Neurospora; Nucleotides; Orotic Acid; Phosphates; Radiometry; Rats; Research; Spectrum Analysis; Uridine | 1965 |
OROTIDINE -5'-PHOSPHATE PYROPHOSPHORYLASE OF WHEAT EMBRYOS.
Topics: Autoradiography; Biochemical Phenomena; Biochemistry; Chromatography; Copper; Diphosphates; Glucosyltransferases; Magnesium; Manganese; NAD; Orotate Phosphoribosyltransferase; Orotic Acid; Oxidoreductases; Research; Triticum; Uracil Nucleotides; Uridine | 1965 |
Enzymatic synthesis of pyrimidine nucleotides; orotidine-5'-phosphate and uridine-5'-phosphate.
Topics: Nucleotides; Phosphates; Pyrimidine Nucleotides; Uracil Nucleotides; Uridine | 1955 |
A new ribose nucleoside from Neurospora; "orotidine".
Topics: Humans; Neurospora; Nucleosides; Orotic Acid; Ribose; Uridine | 1951 |
The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase.
Topics: Alanine; Aspartic Acid; Binding, Competitive; Decarboxylation; Molecular Structure; Mutation; Orotidine-5'-Phosphate Decarboxylase; Phosphates; Saccharomyces cerevisiae; Substrate Specificity; Time Factors; Uridine | 2005 |
Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.
Topics: Biocatalysis; Diphosphates; Drug Design; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Orotate Phosphoribosyltransferase; Plasmodium falciparum; Protein Binding; Protein Conformation; Quantum Theory; Static Electricity; Uridine | 2010 |
Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
Topics: Antimalarials; Catalytic Domain; Crystallography, X-Ray; Cytidine; Humans; Kinetics; Ligands; Malaria, Falciparum; Models, Molecular; Orotidine-5'-Phosphate Decarboxylase; Plasmodium falciparum; Structure-Activity Relationship; Uridine | 2012 |
Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.
Topics: Biocatalysis; Buffers; Decarboxylation; Enzyme Activation; Enzyme Stability; Kinetics; Mutant Proteins; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Osmolar Concentration; Phosphites; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Uridine; Uridine Monophosphate | 2013 |
Synthesis of orotidine by intramolecular nucleosidation.
Topics: Molecular Conformation; Uridine | 2015 |
Orotidine-Containing RNA: Implications for the Hierarchical Selection (Systems Chemistry Emergence) of RNA.
Topics: Base Pairing; Base Sequence; Cytidine; RNA; Transition Temperature; Uracil; Uridine | 2017 |
Extended diagnosis of purine and pyrimidine disorders from urine: LC MS/MS assay development and clinical validation.
Topics: Adenine; Adolescent; Adult; Aminoimidazole Carboxamide; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Female; Humans; Infant; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Quality Control; Reference Values; Ribonucleotides; Tandem Mass Spectrometry; Urea; Uridine | 2019 |
A profound computational study to prioritize the natural compound inhibitors against the
Topics: Antimalarials; Carboxy-Lyases; Enzyme Inhibitors; Molecular Docking Simulation; Molecular Dynamics Simulation; Plasmodium falciparum; Uridine | 2020 |
Disruption or reduced expression of the orotidine-5'-decarboxylase gene pyrG increases citric acid production: a new discovery during recyclable genome editing in Aspergillus niger.
Topics: Aspergillus niger; Citric Acid; Gene Editing; Uridine | 2020 |
Serum Orotidine: A Novel Biomarker of Increased CVD Risk in Type 2 Diabetes Discovered Through Metabolomics Studies.
Topics: Biomarkers; Cardiovascular Diseases; Coronary Disease; Diabetes Mellitus, Type 2; Humans; Metabolomics; Prospective Studies; Risk Factors; Uridine | 2022 |