Page last updated: 2024-08-26

orotidine and orotic acid

orotidine has been researched along with orotic acid in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's11 (39.29)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferris, JP; Joshi, PC1
Schretlen, ED; Tax, WJ; Veerkamp, JH1
Cha, S; Janeway, CM1
Bordugo, A; Burlina, AB; Dionisi-Vici, C; Ferrari, V; Tuchman, M; Zacchello, F1
Bennett, JE; Edman, JC; Kwon-Chung, KJ; Varma, A1
Brusilow, SW; Finkelstein, JE; Hauser, ER; Valle, D1
Brusilow, SW; Hauser, E1
Lin, RC; Snodgrass, PJ1
Gröbner, W; Löffler, W; Reiter, S; Zöllner, N1
Golovinsky, E; Spassova, M1
Harris, ML; Oberholzer, VG1
Fairbanks, LD; Krijt, J; Sebesta, I; Simmonds, HA1
Davies, PM; Fairbanks, LD; Leonard, JV; Sebesta, I; Simmonds, HA1
Daniewska-Michalska, D; Gellert, R; Kukulska, W; Motyl, T; Opechowska-Pacocha, E; Ostrowski, K; Podgurniak, M1
Hariguchi, F; Hayashi, T; Kobayashi, N; Matsuno, T; Okada, Y; Okamoto, T2
Lund, AE1
Allen, JC; Bonham, JR; Downing, M; Duley, JA; Fairbanks, LD; Fensom, A; Guthrie, P; Land, JM; O'Neill, D; Rittey, C; Sharrard, M; Tanner, MS1
Arranz, JA; Burlina, A; Climent, C; Riudor, E; Rodés, M; Roig, M; Rubio, V; Sentís, M1
Arranz, JA; Burlina, AB; Riudor, E; Rodés, M; Rubio, V; Sentís, M1
Egawa, H; Kikuta, H; Kobayashi, K; Nagasaka, H; Tanaka, K; Yorifuji, T1
FOX, JJ; WEMPEN, I; YUNG, N1
HABERMANN, V1
FINK, RM; PYNADATH, TI1
KAPOOR, M; WAYGOOD, ER1
DRELL, W; MICHELSON, AM; MITCHELL, HK1
Bailey, CJ1
Amyes, TL; Goryanova, B; Richard, JP; Spong, K1

Reviews

2 review(s) available for orotidine and orotic acid

ArticleYear
Analogs of pyrimidine and purine mononucleotide precursors as metabolic inhibitors.
    Pharmacology & therapeutics, 1981, Volume: 13, Issue:3

    Topics: Animals; Antimetabolites; Aspartic Acid; Imidazoles; Orotic Acid; Purine Nucleosides; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Triazoles; Uridine

1981
Orotic aciduria and uridine monophosphate synthase: a reappraisal.
    Journal of inherited metabolic disease, 2009, Volume: 32 Suppl 1

    Topics: Adult; Anemia, Megaloblastic; Child; Child, Preschool; Humans; Infant; Kinetics; Metabolic Networks and Pathways; Models, Biological; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine-Pyrimidine Metabolism, Inborn Errors; Uridine; Uridine Monophosphate

2009

Trials

2 trial(s) available for orotidine and orotic acid

ArticleYear
Investigation for the characteristic anticoccidial activity of diclazuril in battery trials.
    The Journal of veterinary medical science, 1996, Volume: 58, Issue:2

    Topics: Animals; Chickens; Coccidiosis; Coccidiostats; Drug Interactions; Drug Resistance; Eimeria; Nitriles; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Triazines; Uracil; Uridine; Uridine Diphosphate Glucose; Uridine Diphosphate N-Acetylglucosamine

1996
Optimization of allopurinol challenge: sample purification, protein intake control, and the use of orotidine response as a discriminative variable improve performance of the test for diagnosing ornithine carbamoyltransferase deficiency.
    Clinical chemistry, 1999, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Allopurinol; Child; Child, Preschool; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Female; Humans; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Proteins; ROC Curve; Sensitivity and Specificity; Uridine

1999

Other Studies

24 other study(ies) available for orotidine and orotic acid

ArticleYear
Chemical evolution from hydrogen cyanide: photochemical decarboxylation of orotic acid and orotate derivatives.
    Science (New York, N.Y.), 1978, Jul-28, Volume: 201, Issue:4353

    Topics: Decarboxylation; Hydrogen Cyanide; Orotic Acid; Photochemistry; Ribonucleotides; Uracil; Uridine; Uridine Monophosphate

1978
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay.
    Clinica chimica acta; international journal of clinical chemistry, 1978, Dec-15, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Aging; Allopurinol; Breast Feeding; Child; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Pregnancy; Radioisotope Dilution Technique; Uridine

1978
Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
    Cancer research, 1977, Volume: 37, Issue:12

    Topics: Azauridine; Cells, Cultured; Lymphoma; Neoplasms, Experimental; Nucleotides; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine Nucleotides; Pyrimidine Nucleotides; Uridine

1977
Allopurinol challenge test in children.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:5

    Topics: Adolescent; Aging; Allopurinol; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea; Uridine

1992
Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-fluoroorotic acid medium.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1992, Volume: 30, Issue:1

    Topics: Animals; Blotting, Southern; Cryptococcus neoformans; Culture Media; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA, Fungal; Humans; Mutation; Nucleic Acid Hybridization; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Restriction Mapping; Transformation, Genetic; Uracil; Uridine

1992
Allopurinol-induced orotidinuria. A test for mutations at the ornithine carbamoyltransferase locus in women.
    The New England journal of medicine, 1990, Jun-07, Volume: 322, Issue:23

    Topics: Adult; Allopurinol; Chromatography, High Pressure Liquid; Female; Genetic Carrier Screening; Heterozygote; Humans; Middle Aged; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uridine

1990
Simple method of measurement of orotic acid and orotidine in urine.
    Journal of chromatography, 1989, Sep-01, Volume: 493, Issue:2

    Topics: Chromatography, High Pressure Liquid; Humans; Nitrobenzoates; Orotic Acid; Spectrophotometry, Ultraviolet; Uridine

1989
Differing effects of arginine deficiency on the urea cycle enzymes of rat liver, cultured hepatocytes and hepatoma cells.
    The Journal of nutrition, 1987, Volume: 117, Issue:11

    Topics: Ammonium Chloride; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Cells, Cultured; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Ornithine Carbamoyltransferase; Orotic Acid; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Urea; Uridine; Valine

1987
Urinary oxipurinol-1-riboside excretion and allopurinol-induced oroticaciduria.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Allopurinol; Chromatography, High Pressure Liquid; Humans; Orotic Acid; Purines; Ribonucleosides; Uridine

1986
Conditions affecting the colorimetry of orotic acid and orotidine in urine.
    Clinical chemistry, 1980, Volume: 26, Issue:3

    Topics: Adult; Age Factors; Child; Child, Preschool; Colorimetry; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Infant; Infant, Newborn; Male; Orotic Acid; Uridine

1980
The allopurinol loading test in detecting obligate heterozygotes for OCT deficiency.
    Journal of inherited metabolic disease, 1994, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Allopurinol; Chromatography, High Pressure Liquid; Female; Genetic Carrier Screening; Humans; Middle Aged; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uridine

1994
The allopurinol loading test for identification of carriers for ornithine carbamoyl transferase deficiency: studies in a healthy control population and females at risk.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Jan-14, Volume: 224, Issue:1

    Topics: Adolescent; Adult; Allopurinol; Child; Female; Heterozygote; Humans; Middle Aged; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Predictive Value of Tests; Risk; Spectrophotometry, Ultraviolet; Uridine

1994
Efficiency of hemodialysis of pyrimidine compounds in patients with chronic renal failure.
    Nephron, 1993, Volume: 64, Issue:2

    Topics: Adult; Aged; Allopurinol; Creatinine; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Orotic Acid; Pseudouridine; Pyrimidines; Renal Dialysis; Uric Acid; Uridine

1993
Antagonistic effect of nucleic acid precursors on the anticoccidial activity of 6-azauracil.
    The Journal of veterinary medical science, 1996, Volume: 58, Issue:2

    Topics: Adenine; Adenosine; Animals; Chickens; Coccidiosis; Coccidiostats; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Eimeria; Food, Fortified; Male; Nucleic Acid Precursors; Orotic Acid; Poultry Diseases; Uracil; Uridine

1996
Quick cancer test developed.
    Journal of the American Dental Association (1939), 1998, Volume: 129, Issue:8

    Topics: Allopurinol; Antimetabolites; Biomarkers, Tumor; DNA; Humans; Neoplasms; Orotic Acid; Pyrimidines; Uridine

1998
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.
    Journal of inherited metabolic disease, 1999, Volume: 22, Issue:2

    Topics: Allopurinol; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolic Diseases; Mitochondria; Muscles; Orotic Acid; Predictive Value of Tests; Sensitivity and Specificity; Urea; Uridine

1999
Influence of dose and age on the response of the allopurinol test for ornithine carbamoyltransferase deficiency in control infants.
    Journal of inherited metabolic disease, 2000, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Age Factors; Allopurinol; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uridine

2000
Successful living-donor liver transplantation from an asymptomatic carrier mother in ornithine transcarbamylase deficiency.
    The Journal of pediatrics, 2001, Volume: 138, Issue:3

    Topics: Adult; Amino Acids; Child; Female; Heterozygote; Humans; Liver Transplantation; Living Donors; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Treatment Outcome; Uridine

2001
Spectrophotometric studies of nucleic acid derivatives and related compounds as a function of pH. IV. On the structure of orotidine. A study of N-methylated orotic acids.
    Biochimica et biophysica acta, 1957, Volume: 23, Issue:2

    Topics: Nucleic Acids; Nucleotides; Orotic Acid; Spectrophotometry; Uridine

1957
Elimination by the urine of orotic acid and orotidine in man after application of 6-azauracil.
    Biochimica et biophysica acta, 1960, Sep-09, Volume: 43

    Topics: Biological Transport; Body Fluids; Humans; Male; Nucleosides; Nucleotides; Orotic Acid; Uracil; Uridine

1960
ENZYMIC PREPARATION OF RADIOACTIVE OROTIDINE 5'-PHOSPHATE.
    Biochimica et biophysica acta, 1965, Feb-08, Volume: 95

    Topics: Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Liver; Neurospora; Nucleotides; Orotic Acid; Phosphates; Radiometry; Rats; Research; Spectrum Analysis; Uridine

1965
OROTIDINE -5'-PHOSPHATE PYROPHOSPHORYLASE OF WHEAT EMBRYOS.
    Canadian journal of biochemistry, 1965, Volume: 43

    Topics: Autoradiography; Biochemical Phenomena; Biochemistry; Chromatography; Copper; Diphosphates; Glucosyltransferases; Magnesium; Manganese; NAD; Orotate Phosphoribosyltransferase; Orotic Acid; Oxidoreductases; Research; Triticum; Uracil Nucleotides; Uridine

1965
A new ribose nucleoside from Neurospora; "orotidine".
    Proceedings of the National Academy of Sciences of the United States of America, 1951, Volume: 37, Issue:7

    Topics: Humans; Neurospora; Nucleosides; Orotic Acid; Ribose; Uridine

1951
Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.
    Biochemistry, 2013, Jan-22, Volume: 52, Issue:3

    Topics: Biocatalysis; Buffers; Decarboxylation; Enzyme Activation; Enzyme Stability; Kinetics; Mutant Proteins; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Osmolar Concentration; Phosphites; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Uridine; Uridine Monophosphate

2013