orotic acid and lysine
orotic acid has been researched along with lysine in 59 studies
Research
Studies (59)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (79.66) | 18.7374 |
| 1990's | 4 (6.78) | 18.2507 |
| 2000's | 5 (8.47) | 29.6817 |
| 2010's | 1 (1.69) | 24.3611 |
| 2020's | 2 (3.39) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Milner, JA; Prior, RL; Visek, WJ | 1 |
| Artemenko, NK; Freidlin, IS; Lyzlova, SN; Nersesova, LS; Petrova, TA | 1 |
| Visek, WJ | 1 |
| Zieve, L | 1 |
| Brusilow, SW; Rajantie, J; Simell, O; Sipilä, I; Valle, DL | 1 |
| Kato, T; Mizutani, N; Sano, M | 1 |
| Bachmann, C; Colombo, JP; Dionisi Vici, C; Gambarara, M; Sabetta, G | 1 |
| Alexiev, C; Golovinsky, E; Halacheva, K; Hubenova, A; Pajpanova, T; Spassova, M; Zhelev, Z | 1 |
| de Parscau, L; Divry, P; Guibaud, P; Hermier, M; Vianey-Liaud, C | 1 |
| Barth, CA; de Vrese, M | 1 |
| Ord, MG; Stocken, LA | 1 |
| Christophe, J; Vandermeers-Piret, MC | 1 |
| Cummins, JE; Rusch, HP | 1 |
| Meerson, FZ; Pomoinitsky, VD | 1 |
| Nasonov, AS | 1 |
| Arnold, EA; Young, KE | 1 |
| Paik, WK; Pearson, DB | 1 |
| Latimer, RG; Mandel, HG; Riis, M | 1 |
| Conrad, ME; Polet, H | 1 |
| Bäckström, S | 1 |
| Cerna, I; Fay, PJ; Klubes, P | 1 |
| Morita, T; Ogata, K; Tsurugi, K | 1 |
| Lee, HW; Paik, WK | 1 |
| Cox, BM; Osman, OH | 1 |
| Chae, CB; Irvin, JL; Krasny, H; Piantadosi, C; Williams, A | 1 |
| Barceló, P; Ferré, LA; Salvatella Viñals, J | 1 |
| Dixon, GH; Smithies, O; Sung, MT | 1 |
| Caroli, J; Goutand, G; Lemonnier, F | 1 |
| Faloona, GR; Fried, M; Stewart, BN | 1 |
| Borgatti, AR; Lenaz, G; Sechi, AM | 2 |
| Held, I; Koenig, H; Wells, W | 1 |
| Moruzzi, G; Sechi, AM; Viviani, R | 1 |
| Sanchez, S | 1 |
| Booth, BA; Sartorelli, AC | 1 |
| Bucknall, RA; Carter, SB | 1 |
| Cohen, S; Hoober, JK | 1 |
| Ifft, KH; Kari, FW; Ulman, EA; Visek, WJ | 1 |
| Hevia, P; Kari, FW; Ulman, EA; Visek, WJ | 1 |
| Fico, ME; Hassan, AS; Milner, JA | 1 |
| Dorfman, RH; Grubmeyer, C; Ozturk, DH; Sacchettini, JC; Scapin, G | 1 |
| Grunstein, M; Ling, X; Thompson, JS | 1 |
| Kirchgessner, M; Kreuzer, M; Vertesy, E | 1 |
| Donati, MA; Filippi, L; Resti, M; Zammarchi, E | 1 |
| Lukkarinen, M; Mattila, K; Näntö-Salonen, K; Pulkki, K; Simell, O | 1 |
| Andersen, GR; Kinzy, TG; Nyborg, J; Pedersen, L; Valente, L | 1 |
| Holden, HM; Neal, TM; Phillips, GN; Raushel, FM; Thoden, JB | 1 |
| BRATTGARD, SO; HYDEN, H; SJOSTRAND, J | 1 |
| HATAKEYAMA, T | 1 |
| ALLFREY, VG; FRENSTER, JH; MIRSKY, AE | 1 |
| FUJIOKA, M; LIEBERMAN, I | 1 |
| CAROLI, J; HAGEGE, A; LEMONNIER, F; MASSON, S | 1 |
| BARRE, Y; CAROLI, J; MOLLE, J; TREMOLIERES, J; VAN DEN DRIESSCHE, J; VIGNERON, M | 1 |
| KORNACKA, L; MALEC, J; WOJNAROWSKA, M; ZAKRZEWSKI, K | 1 |
| Basran, J; Combe, JP; Hothi, P; Leys, D; Munro, AW; Rigby, SE; Scrutton, NS | 1 |
| Ma, C; Wang, X; Xu, P | 1 |
| Dong, YH; Gao, ZQ; Ji, CN; Li, LF; Liu, CP; Liu, Y; Su, XD; Xu, JH | 1 |
| Gornbein, JA; Koos, BJ | 1 |
| Hall, PL; Wilcox, WR; Wittenauer, AL | 1 |
Reviews
1 review(s) available for orotic acid and lysine
| Article | Year |
|---|---|
Conditional deficiencies of ornithine or arginine.
Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Arginine; Citrulline; Female; Glycine; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Lysine; Models, Biological; Ornithine; Orotic Acid; Pregnancy; Protein Deficiency; Urease | 1986 |
Other Studies
58 other study(ies) available for orotic acid and lysine
| Article | Year |
|---|---|
Urea, citrate and orotate excretion in growing rats fed amino acid-deficient diets.
Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Arginine; Citrates; Deficiency Diseases; Lysine; Male; Orotic Acid; Rats; Urea | 1975 |
[Changes in the functional activity of macrophages, their morphology and metabolism under the influence of several biologically active substances].
Topics: Ascorbic Acid; Carbon Radioisotopes; Cathepsins; Chloramphenicol; Chloroquine; Creatine Kinase; Culture Techniques; Cycloheximide; Dactinomycin; Lipopolysaccharides; Lysine; Macrophages; Orotic Acid; Peritoneum; Phagocytosis; Protein Biosynthesis; Puromycin; Rifampin; RNA; Tetracycline; Uridine | 1975 |
Arginine needs, physiological state and usual diets. A reevaluation.
Topics: Animals; Arginine; Body Weight; Creatine; Diet; Fatty Liver; Female; Humans; Lysine; Nutritional Requirements; Orotic Acid; Pregnancy; Wounds and Injuries | 1986 |
Waste nitrogen excretion via amino acid acylation: benzoate and phenylacetate in lysinuric protein intolerance.
Topics: Acylation; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Benzoates; Benzoic Acid; Child; Child, Preschool; Creatinine; Glutamine; Hippurates; Humans; Lysine; Nitrogen; Orotic Acid; Phenylacetates; Urea | 1986 |
Inhibitory effect of intravenous lysine infusion on urea cycle metabolism.
Topics: Adolescent; Amino Acids; Ammonia; Child; Citric Acid Cycle; Citrulline; Depression, Chemical; Female; Humans; Infusions, Intravenous; Lysine; Male; Orotic Acid; Putrescine; Urea | 1987 |
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome: low creatine excretion and effect of citrulline, arginine, or ornithine supplement.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Child, Preschool; Citrulline; Creatine; Female; Humans; Lysine; Male; Ornithine; Orotic Acid; Syndrome | 1987 |
Lysine-orotate potentiates the toxicity of an extract of the mushroom Amanita phalloides.
Topics: Amanitins; Animals; Drug Synergism; Lysine; Male; Mice; Orotic Acid; Protein Binding | 1988 |
[Protein intolerance with lysinuria. Value of orotic aciduria in adjusting treatment with citrulline].
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Diamino; Ammonia; Biological Transport; Cell Membrane; Citrulline; Consanguinity; Dietary Proteins; Humans; Lysine; Male; Orotic Acid; Osteoporosis | 1988 |
Influence of lysine on urea cycle activity and orotate formation in the isolated perfused rat liver.
Topics: Ammonia; Animals; In Vitro Techniques; Kinetics; Liver; Lysine; Male; Ornithine; Orotic Acid; Perfusion; Rats; Rats, Inbred Strains; Urea | 1985 |
Uptake of amino acids and nucleic acid precursors by regenerating rat liver.
Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine | 1972 |
[Effects of lysine deficiency on the rat liver].
Topics: Animals; Carbon Isotopes; Deficiency Diseases; In Vitro Techniques; Leucine; Liver; Lysine; Orotic Acid; Protein Biosynthesis; Rats; RNA; Thymidine; Uracil | 1964 |
Limited DNA synthesis in the absence of protein synthesis in Physarum polycephalum.
Topics: Anti-Bacterial Agents; Carbon Isotopes; Cell Division; Cell Nucleus; Cycloheximide; DNA; Floxuridine; Leucine; Lysine; Myxomycetes; Orotic Acid; Protein Biosynthesis; Thymidine; Tritium | 1966 |
The role of high-energy phosphate compounds in the development of cardiac hypertrophy.
Topics: Acclimatization; Adenosine Triphosphate; Alanine; Animals; Aorta; Atmosphere Exposure Chambers; Carbon Isotopes; Cardiomegaly; Cell Nucleus; DNA; Lysine; Male; Methionine; Mitochondria, Muscle; Orotic Acid; Oxygen; Rats; RNA; Thymidine; Tritium | 1972 |
[Metabolism of information RNAs from rat liver free and membrane-bound polyribosomes in a cell-free system of protein synthesis].
Topics: Animals; Carbon Radioisotopes; Cell-Free System; Centrifugation, Zonal; Liver; Lysine; Male; Membranes; Orotic Acid; Polyribosomes; Protein Biosynthesis; Protein Precursors; Rats; RNA, Messenger; RNA, Ribosomal | 1974 |
Heterogeneity of chromatin: fractionation of sonicated rat liver chromatin by partial precipitation with Mg2+.
Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Chromatin; Chromosomes; DNA; Electrophoresis, Polyacrylamide Gel; Histones; Liver; Lysine; Magnesium; Male; Molecular Weight; Nucleoproteins; Orotic Acid; Peptides; Protein Binding; Rats; RNA; Solubility; Spectrophotometry, Ultraviolet; Templates, Genetic; Tritium; Ultracentrifugation; Ultrasonics | 1974 |
Studies on histone acetylation during thyroxine-induced amphibian metamorphosis.
Topics: Acetates; Animals; Carbon Isotopes; Electrophoresis; Histones; Kinetics; Lectins; Lysine; Metamorphosis, Biological; Orotic Acid; Rana catesbeiana; RNA; Thyroxine; Trichloroacetic Acid; Tritium | 1972 |
The actions of thioguanine in Bacillus cereus.
Topics: Bacillus cereus; DNA, Bacterial; Flagella; Glycine; Guanine; In Vitro Techniques; Lysine; Mercaptopurine; Orotic Acid; Penicillinase; Phosphates; RNA, Bacterial; Thioguanine; Uracil | 1965 |
Malaria: extracellular amino acid requirements for in vitro growth of erythrocytic forms of Plasmodium knowlesi.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Culture Techniques; Cystine; DNA; Erythrocytes; Glutamine; Haplorhini; Histidine; Isoleucine; Lysine; Methionine; Orotic Acid; Plasmodium; Tyrosine | 1968 |
[Passage of radioactive substances between a labelled graft and its unmarked host. Autoradiographic study of sea urchin embryo submitted to transplantation].
Topics: Alanine; Amino Acids; Animals; Autoradiography; Echinodermata; Embryo Transfer; Leucine; Lysine; Mosaicism; Nucleic Acids; Orotic Acid; Transplantation, Homologous; Tritium; Uridine | 1969 |
Effect of chlorpromazine on cell wall biosynthesis and incorporation of orotic acid into nucleic acids in Bacillus megaterium.
Topics: Adenine; Bacillus megaterium; Bacterial Proteins; Carbon Isotopes; Cell Wall; Chlorpromazine; DNA, Bacterial; Formates; Lysine; Models, Biological; Nucleic Acids; Orotic Acid; Pimelic Acids; Promazine; RNA; RNA, Bacterial; Sulfoxides; Thymidine; Time Factors; Trifluoperazine; Uridine | 1971 |
Studies on the metabolism of ribosomal structural proteins of regenerating rat liver. Sites of biosynthesis of structural proteins of large subunit and of their assembly with RNA moiety.
Topics: Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Electrophoresis, Disc; Hepatectomy; Leucine; Liver; Liver Regeneration; Lysine; Male; Nucleoproteins; Orotic Acid; Protein Biosynthesis; Rats; Ribosomes; RNA, Ribosomal; Tritium; Valine | 1972 |
Histone methylation during hepatic regeneration in rat.
Topics: Animals; Arginine; Carbon Isotopes; Cytoplasm; DNA; Hepatectomy; Histones; Kinetics; Liver; Liver Regeneration; Lysine; Male; Methylation; Methyltransferases; Orotic Acid; Proteins; Rats; RNA; S-Adenosylmethionine; Thymidine; Tritium | 1972 |
Inhibition of the development of tolerance to morphine in rats by drugs which inhibit ribonucleic acid or protein synthesis.
Topics: Animals; Brain; Carbon Isotopes; Cycloheximide; Dactinomycin; Depression, Chemical; Drug Tolerance; Female; Fluorouracil; Lysine; Male; Mercaptopurine; Morphine; Orotic Acid; Protein Biosynthesis; Puromycin; Rats; RNA | 1970 |
Inhibition of thymidine phosphorylation and DNA and histone synthesis in Ehrlich ascites carcinoma.
Topics: Aldehydes; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Cycloheximide; Cytarabine; Cytoplasm; DNA; Glycine; Histones; Hydroxyurea; In Vitro Techniques; Lysine; Mice; Mitomycins; Nucleotides; Orotic Acid; Puromycin; Thiosemicarbazones; Thymidine; Tritium | 1970 |
[Results of personal experience with a sulfamide preparation associated with lysine orotate and pyridoxine hydrochloride, in the treatment of rheumatism of degenerative origin].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Lysine; Male; Middle Aged; Orotic Acid; Pyridoxine; Sulfonamides | 1970 |
Phosphorylation and synthesis of histones in regenerating rat liver.
Topics: Acrylates; Amino Acids; Animals; Autoradiography; Cell Nucleus; Chromatography, Ion Exchange; Electrophoresis; Gels; Hepatectomy; Histones; Hydrogen-Ion Concentration; Liver; Liver Regeneration; Lysine; Male; Orotic Acid; Osmolar Concentration; Phosphates; Phosphopeptides; Phosphorus Isotopes; Polymers; Rats; RNA; Starch; Tritium | 1971 |
[Action of lysine on the hyperammoniema of the cirrhotic patient].
Topics: Amino Acids; Ammonia; Humans; Injections, Intravenous; Liver Cirrhosis; Lysine; Male; Middle Aged; Orotic Acid; Perfusion; Time Factors | 1971 |
The effects of actinomycin D on the siosynthesis of plasma lipoproteins.
Topics: Animals; Carbon Isotopes; Centrifugation, Zonal; Dactinomycin; Depression, Chemical; Lipoproteins; Liver; Lysine; Male; Orotic Acid; Perfusion; Proteins; Rats; Templates, Genetic; Tritium | 1968 |
[Effects of lysine and orotic acid on the lipid composition of the brain of lysine-deficient rats].
Topics: Animals; Brain; Deficiency Diseases; Lipid Metabolism; Lysine; Orotic Acid; Rats | 1968 |
[Changes of blood and hepatic cholesterol in lysine deficient rats: effect of lysine and orotic acid].
Topics: Animals; Cholesterol; Deficiency Diseases; Liver; Lysine; Orotic Acid; Rats | 1968 |
Metabolic effects of azaserine in rat brain.
Topics: Adenine; Animals; Azaserine; Brain; Carbon Isotopes; Centrifugation; Chromatography, Ion Exchange; Chromatography, Paper; Female; Glycine; Lysine; Nerve Tissue Proteins; Nucleotides; Orotic Acid; Paraplegia; Phenylalanine; Purines; Pyrimidines; Rats; RNA; Spectrum Analysis; Tritium | 1969 |
Effect of orotic acid in lysine deficient rats.
Topics: Animals; Deficiency Diseases; Depression, Chemical; Diet; Growth; Lipids; Liver; Lysine; Nucleic Acids; Orotic Acid; Protein Biosynthesis; Rats | 1969 |
[The formation and role of nucleoli in the oocytes of Triturus helveticus Raz--an autoradiographic and ultrastructural study].
Topics: Animals; Autoradiography; Cell Nucleolus; Chromosomes; Female; Histocytochemistry; Lysine; Microscopy, Electron; Orotic Acid; Ovum; Tritium; Urodela | 1969 |
The synergistic anti-neoplastic activity of combinations of mitomycins with either 6-thioguanine or 5-fluorouracil.
Topics: Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Synergism; Female; Fluorouracil; In Vitro Techniques; Leukemia L1210; Lysine; Male; Mice; Mitomycins; Mortality; Neoplasm Proteins; Neoplasm Transplantation; Orotic Acid; RNA, Neoplasm; Sarcoma 180; Thioguanine; Thymidine; Thymidine Kinase | 1965 |
A reversible inhibitor of nucleic acid synthesis.
Topics: Animals; Benzimidazoles; Cattle; Chick Embryo; Culture Media; Culture Techniques; DNA; Fibroblasts; HeLa Cells; Kidney; L Cells; Lysine; Nucleosides; Orotic Acid; RNA; Thymidine; Tritium; Uridine | 1967 |
Epidermal growth factor. I. The stimulation of protein and ribonucleic acid synthesis in chick embryo epidermis.
Topics: Animals; Carbon Isotopes; Chick Embryo; Culture Techniques; Dactinomycin; Growth Substances; Lysine; Orotic Acid; Protein Biosynthesis; Proteins; Puromycin; RNA; Skin; Submandibular Gland; Thymidine; Uridine | 1967 |
Fatty liver of growing rats fed excess lysine and its prevention by adenine or allopurinol.
Topics: Adenine; Allopurinol; Animals; Arginine; Diet; Fatty Liver; Lipid Metabolism; Liver; Lysine; Male; Orotic Acid; Rats | 1981 |
Orotic aciduria caused by feeding excess lysine to growing rats.
Topics: Ammonia; Animals; Arginine; Body Weight; Creatinine; Eating; Lysine; Male; Orotic Acid; Rats; Rats, Inbred Strains; Urea | 1981 |
The influence of excess lysine on urea cycle operation and pyrimidine biosynthesis.
Topics: Amino Acids; Ammonium Chloride; Animals; Arginase; Arginine; Dose-Response Relationship, Drug; Liver; Lysine; Orotic Acid; Rats; Rats, Inbred Strains; Urea | 1982 |
Structure and function of Salmonella typhimurium orotate phosphoribosyltransferase: protein complementation reveals shared active sites.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Chromatography, Ion Exchange; Conserved Sequence; Electrophoresis, Polyacrylamide Gel; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Protein Conformation; Salmonella typhimurium; Sequence Homology, Amino Acid | 1995 |
Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast.
Topics: Amino Acid Sequence; Chromosomes, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Histones; Lysine; Molecular Sequence Data; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Saccharomyces cerevisiae; Telomere | 1994 |
Response of renal orotic acid and creatinine to treatments affecting metabolic protein supply of ruminants.
Topics: Allantoin; Animal Feed; Animals; Creatinine; Dietary Proteins; Kidney; Lysine; Male; Orotic Acid; Rumen; Ruminants; Sheep; Urea | 1995 |
Cryptogenic hepatitis masking the diagnosis of ornithine transcarbamylase deficiency.
Topics: Absorption; Ammonia; Arginine; Child, Preschool; Citrulline; Diagnosis, Differential; Dietary Proteins; Female; Glutamine; Hepatitis; Humans; Infant; Lysine; Ornithine; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Urea | 1996 |
Effect of lysine infusion on urea cycle in lysinuric protein intolerance.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Systems, Basic; Amino Acids; Ammonia; Carrier Proteins; Female; Humans; Lysine; Male; Membrane Proteins; Middle Aged; Mutation; Orotic Acid; Urea | 2000 |
Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Topics: Amino Acid Substitution; Binding Sites; Carbohydrate Metabolism; Crystallography, X-Ray; Guanosine Diphosphate; Lysine; Magnesium; Models, Molecular; Mutation; Orotic Acid; Peptide Elongation Factor 1; Protein Conformation; Yeasts | 2001 |
Molecular structure of dihydroorotase: a paradigm for catalysis through the use of a binuclear metal center.
Topics: Amino Acid Sequence; Aryldialkylphosphatase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Catalysis; Crystallography, X-Ray; Dihydroorotase; Dimerization; Escherichia coli; Esterases; Humans; Lysine; Molecular Sequence Data; Orotic Acid; Structure-Activity Relationship; Zinc | 2001 |
Incorporation of orotic acid-14c and lysine-14c in regenerating single nerve cells.
Topics: Biochemical Phenomena; Lysine; Neurons; Orotic Acid; Regeneration | 1958 |
[Studies on nutrition and hepatic injury. 4. Studies on experimental fatty liver; effects of addition of lipoic acid, orotic acid, lvsine, threonine, and fermented sovbeans].
Topics: Fatty Liver; Glycine max; Liver Diseases; Lysine; Nutritional Status; Orotic Acid; Thioctic Acid; Threonine | 1961 |
REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES.
Topics: Alanine; Animals; Carbon Isotopes; Cattle; Chromatin; Chromosomes; DNA; Electrons; Genetics; Interphase; Lymphocytes; Lysine; Microscopy; Microscopy, Electron; Nucleosides; Orotic Acid; Proteins; Research; Thymus Gland | 1963 |
A ZN++ REQUIREMENT FOR SYNTHESIS OF DEOXYRIBONUCLEIC ACID BY RAT LIVER.
Topics: Antimetabolites; Cell Nucleus; DNA; Edetic Acid; Hepatectomy; Liver; Lysine; Magnesium; Metabolism; Orotic Acid; Perfusion; Pharmacology; Phenylalanine; Proteins; Rats; Research; Thymidine; Zinc | 1964 |
[A NEW TREATMENT OF EXCESS BLOOD AMMONIA IN CIRRHOTIC PATIENTS: LYSINE OROTATE].
Topics: Ammonia; Blood Chemical Analysis; Drug Therapy; Humans; Liver Cirrhosis; Lysine; Orotic Acid | 1964 |
[LYSINE OROTATE IN HEPATOLOGY].
Topics: Alcoholism; Chemistry, Pharmaceutical; Drug Therapy; Gastroenterology; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Humans; Jaundice; Liver Cirrhosis; Lysine; Orotic Acid; Portacaval Shunt, Surgical; Toxicology | 1964 |
EFFECT OF PURINES AND SOME OF THEIR ANALOGUES ON PROTEIN AND RNA SYNTHESIS IN ISOLATED NUCLEI.
Topics: Antibody Formation; Antimetabolites; Antineoplastic Agents; Carbon Isotopes; Cell Nucleus; Cytosine; Guanine; Leucine; Leukocytes; Lysine; Mercaptopurine; Metabolism; Orotic Acid; Pharmacology; Proteins; Purines; Research; RNA; Thioguanine; Uracil; Uric Acid; Xanthines | 1964 |
Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis.
Topics: Catalysis; Dihydroorotate Dehydrogenase; Dimerization; Electrochemistry; Electron Transport; Flavin Mononucleotide; Flavins; Lactococcus lactis; Lysine; Mutagenesis, Site-Directed; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Structure, Tertiary; Tyrosine | 2006 |
Orotate phosphoribosyltransferase from Corynebacterium ammoniagenes lacking a conserved lysine.
Topics: Bacterial Proteins; Cations, Divalent; Chromatography, Gel; Cloning, Molecular; Coenzymes; Conserved Sequence; Corynebacterium; Dimerization; Diphosphates; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Molecular Weight; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Recombinant Proteins; Sequence Analysis, DNA; Uridine Monophosphate | 2007 |
Structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Dental Caries; Dihydroorotate Dehydrogenase; Dimerization; Escherichia coli; Flavin Mononucleotide; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Subunits; Pyrimidines; Recombinant Proteins; Sequence Homology, Amino Acid; Streptococcus mutans; Substrate Specificity; X-Ray Diffraction | 2011 |
Early pregnancy metabolites predict gestational diabetes mellitus: implications for fetal programming.
Topics: Adult; Alanine; Arginine; Carnitine; Case-Control Studies; Diabetes, Gestational; Diet Therapy; Dopamine; Early Diagnosis; Epigenesis, Genetic; Female; Fetal Development; Gestational Age; Glucose Tolerance Test; Glucuronides; Humans; Hypoglycemic Agents; Lactones; Lysine; Meglutol; Metabolomics; Neopterin; Orotic Acid; Phenols; Pregnancy; Ribonucleosides; Sulfides | 2021 |
Proximal urea cycle defects are challenging to detect with newborn screening: Results of a prospective pilot study using post-analytical tools.
Topics: Amino Acids; Ammonia; Glutamine; Humans; Infant, Newborn; Lysine; Neonatal Screening; Orotic Acid; Pilot Projects; Prospective Studies; Urea | 2022 |