ornithine has been researched along with spermidine in 241 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 186 (77.18) | 18.7374 |
| 1990's | 24 (9.96) | 18.2507 |
| 2000's | 13 (5.39) | 29.6817 |
| 2010's | 13 (5.39) | 24.3611 |
| 2020's | 5 (2.07) | 2.80 |
| Authors | Studies |
|---|---|
| Bey, P; Danzin, C; Jung, M; Mamont, P; Tardif, C; Van Dorsselaer, V | 1 |
| Harik, SI; Schwerin, F; Wehle, SU | 1 |
| Russell, DH; Stambrook, PJ | 1 |
| Linebaugh, BE; Mulder, JA; Rillema, JA | 1 |
| Mamont, PS; McCann, PP; Tardif, C | 1 |
| Scamans, E; Tyms, AS; Williamson, JD | 1 |
| Morris, DR; Whitney, PA | 1 |
| Stevens, L; Winther, MD | 1 |
| Bey, P; Danzin, C; Grove, J; Jung, MJ | 1 |
| Marton, LJ; Seidenfeld, J | 2 |
| Knödgen, B; Seiler, N | 1 |
| Canellakis, ZN; Williams-Ashman, HG | 1 |
| Keir, HM; Melvin, MA; Wallace, HM | 1 |
| Alhonen-Hongisto, L; Jänne, J; Kallio, A; Pösö, H | 1 |
| Bacchi, CJ; Garofalo, J; Hutner, SH; Lipschik, GY; Vergara, C | 1 |
| McCormick, F | 1 |
| Brinkley, BR; Nishioka, K; Rao, PN; Sunkara, PS | 1 |
| Jänne, J; Koso, P; Piik, K; Pulkkinen, P | 1 |
| Bey, P; Duchesne, MC; Grove, J; Mamont, PS | 1 |
| Duchesne, MC; Grove, J; Mamont, PS; Tardif, C | 1 |
| Knutson, JC; Morris, DR | 1 |
| Guha, SK; Hölttä, E; Jänne, J | 1 |
| Stevens, L; Winther, M | 1 |
| Abdel-Monem, MM; Newton, NE | 1 |
| Jorstad, CM; Morris, DR; Seyfried, CE | 1 |
| Duffy, PE; Kremzner, LT | 1 |
| Asada, A; Gohda, E; Inoue, H; Mori, Y; Takeda, Y; Takigawa, M | 1 |
| Gohda, E; Inoue, H; Kato, Y; Takeda, Y; Tamada, F | 1 |
| Bey, P; Böhlen, P; Mamont, PS; McCann, PP; Schuber, F; Tardif, C | 1 |
| Tait, GH | 1 |
| Bolin, RW; Cummings, DJ | 1 |
| Bachrach, U; Fischer, R; Klein, I | 1 |
| Adachi, K; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M | 1 |
| Holowczak, JA; Lanzer, W | 1 |
| Hiller, JM; Kremzner, LT; Simon, EJ | 1 |
| Ali, MR; Holaday, NJ; Jeevanandam, M | 1 |
| Dalla Via, L; Garlid, KD; Siliprandi, D; Toninello, A | 1 |
| Cler, JA; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Linebaugh, BE; Rillema, JA | 1 |
| Alunda, JM; Balaña-Fouce, R; Escribano, MI | 1 |
| Kovacs, JA; Lipschik, GY; Masur, H | 1 |
| Baby, TG; Joseph, K | 1 |
| Blachier, F; Darcy-Vrillon, B; Duée, PH; Malaisse, WJ; Sener, A | 1 |
| Dunzendorfer, U; Knöner, M | 1 |
| Chen, KY; Cheng, S | 1 |
| Alhonen, L; Eloranta, T; Hirvonen, A; Hyvönen, T; Jänne, J | 1 |
| Davis, RH; Ristow, JL | 1 |
| Eichler, W | 1 |
| Kadofuku, T; Sato, T; Shinki, T; Suda, T; Tanaka, H | 1 |
| Ekker, M; Sourkes, TL | 1 |
| Dascombe, MJ; Haegele, KD | 1 |
| Hollingdale, MR; McCann, PP; Sjoerdsma, A | 1 |
| Clark, RS; McGovern, KA; Pegg, AE | 1 |
| Meilhoc, E; Moutin, MJ; Osborne, HB; Romani, BH | 1 |
| Gerner, EW; Mamont, PS | 1 |
| Boldizsár, M; Holczinger, L; Kremmer, T | 1 |
| Ehrke, MJ; Eppolito, C; Mihich, E; Porter, CW | 1 |
| Inaba, M; Ishimura, E; Matsui-Yuasa, I; Morii, H; Morisada, S; Morisawa, S; Nishizawa, Y; Otani, S; Yukioka, K; Yukioka, M | 1 |
| Green, CD; Hoggard, N | 1 |
| Bremner, AF; Coombs, GH; Lockwood, BC; North, MJ | 1 |
| Berger, FG; Porter, CW | 1 |
| Bacchi, CJ; Giffin, BF; McCann, PP | 1 |
| Gerner, EW; Glass, JR | 1 |
| Igarashi, K; Kashiwagi, K | 1 |
| Algranati, ID; Cataldi, AA | 1 |
| Hougaard, DM; Larsson, LI; Nielsen, JH | 1 |
| Bitonti, AJ; Byers, TJ; Kim, BG; McCann, PP; Sobota, A | 1 |
| Alhonen-Hongisto, L; Levin, VA; Marton, LJ | 1 |
| Homma, Y; Numata, I; Oyasu, R; Ozono, S; Seidenfeld, J | 1 |
| Kufe, DW; Shafman, T; Watanabe, T | 1 |
| Bergeron, RJ; Cavanaugh, PF; Ganis, B; Kelly, E; Porter, CW; Stolowich, N | 1 |
| Bolkenius, FN; Seiler, N | 1 |
| Franzen, MA; Mitchell, JL; Qasba, P; Stofko, RE | 1 |
| Pegg, AE; Shirahata, A | 1 |
| Königk, E; Putfarken, B | 1 |
| Seidenfeld, J | 1 |
| Fuller, DJ; Gerner, EW; Glass, JR; Sertich, GJ | 1 |
| Heby, O; Russell, DH | 2 |
| Brandt, JT; Fausto, N; Pierce, DA | 1 |
| Herbst, EJ; Lawler, D; Rothaus, K; Wyatt, GR | 1 |
| Hölttä, E; Jänne, J | 3 |
| Hannonen, P; Hölttä, E; Jänne, J; Pispa, J | 1 |
| Setlow, P | 1 |
| Alpert, NR; Hamrell, BB; Russell, DH; Shiverick, KT | 1 |
| Feldman, MJ; Russell, DH | 1 |
| Coppoc, GL; Weber, G; Williams-Ashman, HG | 1 |
| Cavia, E; Webb, TE | 1 |
| Lembach, KJ | 1 |
| Kremzner, LT; Sturman, JA | 2 |
| Cohen, SS; Lapi, L; Massey, S; Rubenstein, KE; Streibel, E | 1 |
| Cohen, SS | 1 |
| Bell, CA; Munro, GF | 1 |
| Bode, VC; Harrison, DP | 1 |
| Russell, DH | 3 |
| Srinivasan, PR; Young, DV | 1 |
| Fillingame, RH; Morris, DR | 1 |
| Tabor, CW; Tabor, H | 1 |
| Fausto, N | 1 |
| McVicker, TA; Russell, DH | 2 |
| MacIndoe, JH; Turkington, RW | 1 |
| Domschke, S; Söling, HD | 1 |
| Inoue, H; Ono, M; Takeda, Y | 1 |
| Manen, CA; Russell, DH | 1 |
| Kay, JE; Lindsay, VJ | 1 |
| Ballesteros, LM; Hernandez, O; Mendez, D; Rosado, A | 1 |
| Mitchell, JL; Rusch, HP | 1 |
| Hölttä, E; Jänne, J; Sinervirta, R | 1 |
| Heby, O; Russell, DH; Sauter, S | 1 |
| Karrer, E; Warren, RA | 1 |
| Asada, A; Inoue, H; Kato, Y; Shiba, K; Tanioka, H | 1 |
| Gaull, GE; Sturman, JA | 1 |
| Oka, T; Perry, JW | 1 |
| Hannonen, P; Jänne, J; Raina, A | 1 |
| McVicker, TA; Russel, DH | 1 |
| Bellantone, RA; Canellakis, ES; Friedman, SJ | 1 |
| Kuttan, R; Radhakrishnan, AN | 2 |
| Gibson, W; Roizman, B | 1 |
| Jänne, J; Käpyaho, K; Kousa, M; Lauharanta, J; Linnamaa, K; Mustakallio, K | 1 |
| Bacchi, CJ; Clarkson, AB; McCann, PP; Mellow, GH; Nathan, HC; Sjoerdsma, A | 1 |
| Jänne, J; Käpyaho, K; Kariniemi, AL; Virtanen, I | 1 |
| Cramer, CL; Davis, RH; Paulus, TJ | 1 |
| Hölttä, E; Hovi, T; Jänne, J; Vaheri, A; Vartio, T | 1 |
| Chambaz, EM; Duperray, A; Madani, C | 1 |
| Tyms, AS; Williamson, JD | 1 |
| Coffino, P; Marton, LJ; McConlogue, LC | 1 |
| Fields, A; Gibson, W; Irmiere, A; LaFemina, R; van Breemen, R | 1 |
| Fout, GS; Mapoles, JE; Medappa, KC; Rueckert, RR | 1 |
| Gordon, AM; Keir, HM; Pearson, CK; Wallace, HM | 1 |
| Gillin, FD; McCann, PP; Reiner, DS | 1 |
| Deen, DF; Hung, DT; Marton, LJ; Shafer, RH | 1 |
| Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE | 1 |
| Jänne, J; Käpyaho, K; Lauharanta, J | 2 |
| Kelly, M; McCann, PP; Schindler, J | 1 |
| Belleville, F; Brossat, B; Metz, R; Nabet, P; Straczek, J | 1 |
| Covey, DF; Fair, WR; Heston, WD; Kadmon, D | 1 |
| Bethell, DR; Erwin, BG; Pegg, AE | 1 |
| Kufe, D; Shafman, T; Sugiura, M | 1 |
| Agam, G; Gartner, TK; Livne, A | 1 |
| Mamont, PS; Rudkin, BB; Seiler, N | 1 |
| Griffin, J; Kufe, D; Mitchell, T; Shafman, T; Sugiura, M | 1 |
| Alhonen-Hongisto, L; Deen, DF; Marton, LJ | 1 |
| Cavanaugh, PF; Pavelic, ZP; Porter, CW | 1 |
| Manni, A; Wright, C | 1 |
| Alhonen-Hongisto, L; Elo, H; Fagerström, R; Jänne, J; Laine, R | 1 |
| Griffin, J; Kufe, DW; Mitchell, T; Shafman, T | 1 |
| Heby, O; Kanje, M; Oredsson, SM | 1 |
| Bartolome, J; Persons, D; Slotkin, TA; Whitmore, WL | 1 |
| Igarashi, K; Morris, DR | 1 |
| Altiere, RJ; Gillespie, MN; Hacker, AD; Olson, JW | 1 |
| Bergeron, RJ; Casero, RA; Porter, CW | 1 |
| Pegg, AE | 1 |
| Benrezzak, O; Morisset, J | 1 |
| Davis, RH; Paulus, TJ | 2 |
| Bullock, MW; Fiala, RR; Mowery, PC; Tsou, HR | 1 |
| Campione, AL; Van Winkle, LJ | 1 |
| Daikuhara, Y; Gohda, E; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M | 1 |
| Anehus, S; Heby, O; Oredsson, S | 1 |
| Alhonen-Hongisto, L; Jänne, J | 1 |
| Deen, DF; Marton, LJ; Seidenfeld, J | 1 |
| Gray, JW; Marton, LJ; Seidenfeld, J | 1 |
| Fozard, JR; Grove, J; Prakash, NJ | 1 |
| Seiler, N | 1 |
| Alhonen-Hongisto, L; Jänne, J; Seppänen, P | 1 |
| Fowler, SK; Nishioka, K; Sunkara, PS | 1 |
| Bethell, DR; Pegg, AE | 1 |
| Grove, J; Joder-Ohlenbusch, AM; Mamont, PS; Nussli, M | 1 |
| Bethell, DR; Hibasami, H; Matsui, I; Pegg, AE | 1 |
| Erwin, BG; Florini, JR; Pegg, AE; Richman, RA; Stoscheck, CM | 1 |
| Jänne, J; Käpyaho, K; Linnamaa, K | 1 |
| Seppänen, P | 1 |
| Boutwell, RK; Simsiman, RC; Takigawa, M; Verma, AK | 1 |
| Barnes, GA; Bartolome, J; Lerea, L; Seidler, FJ; Slotkin, TA; Trepanier, PA; Weigel, SJ; Whitmore, WL | 1 |
| Deen, DF; Marton, LJ; Oredsson, SM; Tofilon, PJ | 1 |
| McCann, PP; Pegg, AE | 1 |
| Hougaard, DM; Larsson, LI | 1 |
| Suzuki, F; Takano, T; Takigawa, M | 1 |
| Kersten, H; Kersten, W; Mach, M | 1 |
| Henningsson, AC; Henningsson, S; Nilsson, M; Tjälve, H | 1 |
| Harada, JJ; Morris, DR; Porter, CW | 1 |
| Persson, L | 1 |
| Hamana, K; Matsuzaki, S; Suzuki, M | 1 |
| Forbes, WR; Yeager, RK | 1 |
| Higaki, I; Kinoshita, H; Matsui-Yuasa, I; Otani, S; Terakura, M | 1 |
| Diegelman, P; Kramer, D; Porter, CW; Regenass, U; Schneider, P; Stanek, J | 1 |
| Blachier, F; Cherbuy, C; Darcy-Vrillon, B; Duée, PH; Hellio, N; M'Rabet-Touil, H; Robert, V | 1 |
| Byus, CV; Hawel, L; Tjandrawinata, RR | 1 |
| Alakuijala, L; Alhonen, L; Halmekytö, M; Jänne, J | 1 |
| Coker, NJ; Henley, CM; Salzer, TA | 1 |
| Laube, G; Veh, RW | 1 |
| Byus, CV; Pastorian, KE | 1 |
| Czernichow, B; Galluser, M; Gossé, F; Nsi-Emvo, E; Raul, F | 1 |
| Calandra, RS; Frungieri, MB; González-Calvar, SI; Rulli, SB; Suescun, MO | 1 |
| Begay, CK; Holaday, NJ; Jeevanadam, M; Petersen, SR | 1 |
| Cowley, T; McPherson, A; Walters, DR | 1 |
| Andersen, SC; Bastola, DR; Minocha, SC | 1 |
| Blachier, F; Duée, PH; Mayeur, C; Robert, V; Selamnia, M | 1 |
| Bauer, PM; Buga, GM; Fukuto, JM; Ignarro, LJ; Wei, LH | 1 |
| Dideberg, O; Sainz, G; Stalon, V; Tricot, C; Villeret, V | 1 |
| Duranton, B; Gossé, F; Hasselmann, M; Raul, F; Schleiffer, R | 1 |
| Meurer-Grimes, B; Rovira, I; Walters, D | 1 |
| Hawker, JR; Kelly, KA; Li, H; Meininger, CJ; Morris, SM; Wu, G | 1 |
| Bhatnagar, P; Minocha, R; Minocha, SC | 1 |
| Biol-N'Garagba, MC; George, P; Greco, S; Hugueny, I; Louisot, P | 1 |
| McQuarrie, SA; Srinath, P; Suresh, MR | 1 |
| RAINA, A | 1 |
| DaMatta, RA; de Mello, FG; de Souza, W; Seabra, SH | 1 |
| Bazer, FW; Hu, J; Johnson, GA; Spencer, TE; Wu, G | 1 |
| Díaz-Troya, S; Najib, S; Sánchez-Margalet, V | 1 |
| Granchi, L; Guerrini, S; Mangani, S; Vincenzini, M | 1 |
| Geller, DA; Ikeda, A; Jeyabalan, G; Kaizu, T; Murase, N; Reid, KM; Shao, L; Tsung, A; Wu, G | 1 |
| Cook, T; Feagin, JE; Keithly, JS; Morada, M; Roos, D; Wu, G; Yarlett, N; Zhu, G | 1 |
| Ando, A; Furuta, K; Igarashi, K; Ito, S; Kaneko, S; Maeda, M; Matsumura, M; Nishimura, K; Okuda-Ashitaka, E; Suzuki, M | 1 |
| Long, S; Minocha, R; Minocha, SC; Mohapatra, S | 1 |
| Aoki, M; Denbow, DM; Furuse, M; Hamasu, K; Kabuki, Y; Kawada, Y; Kurauchi, I; Morishita, K; Shigemi, K; Yamane, H | 1 |
| Guzmán-de-Peña, D; Ruiz-Herrera, J; Valdés-Santiago, L | 1 |
| Lu, D; Peterson, LA; Phillips, MB; Sullivan, MM | 1 |
| Long, S; Majumdar, R; Minocha, R; Minocha, SC; Shao, L | 1 |
| Cynober, L; De Bandt, JP; Ramani, D | 1 |
| Bazer, FW; Burghardt, RC; Dunlap, KA; Lin, G; Satterfield, MC; Wang, X; Wu, G; Ying, W | 1 |
| Kook, M; Son, HM; Yi, TH | 1 |
| Doki, Y; Ishii, H; Kano, Y; Kawamoto, K; Konno, M; Koseki, J; Matsui, H; Mori, M; Nishida, N | 1 |
| Bazer, FW; Li, H; Meininger, CJ; Wu, G | 1 |
| Wang, W; Xia, X; Zhang, B; Zhang, Q; Zhang, W | 1 |
| Faustmann, G; Gruber, HJ; Magnes, C; Meinitzer, A; Obermayer-Pietsch, B; Ribalta, J; Rock, E; Roob, JM; Tiran, B; Winklhofer-Roob, BM | 1 |
| Aso, K; Furuse, M; Harada, D; Ikeda, K; Nagamachi, S; Takahashi, Y | 1 |
| Ahmadpour, A; Christensen, RG; Ineck, NE; Murdoch, GK; Reichhardt, CC; Thornton, KJ | 1 |
| Karamichos, D; McKay, TB; Priyadarsini, S; Rowsey, T | 1 |
| Buezo, J; Cerdán, D; Cornejo, A; Esteban, R; Gogorcena, Y; López-Gómez, P; Martínez-Merino, V; Moran, JF; Royo, B; Tavladoraki, P; Urra, M | 1 |
| Abraham, SJK; Dedeepiya, VD; Ikewaki, N; Iwasaki, M; Levy, GA; Preethy, S; Raghavan, K; Ranganathan, N; Senthilkumar, R; Srinivasan, S; Yamamoto, N | 1 |
| Bělíček, J; Briozzo, P; Ćavar Zeljković, S; De Diego, N; Frömmel, J; Jagic, F; Kopečná, M; Kopečný, D; Kopečný, DJ; Ľuptáková, E; Moréra, S; Nisler, J; Tarkowski, P; Vigouroux, A | 1 |
10 review(s) available for ornithine and spermidine
| Article | Year |
|---|---|
Spermine, spermidine and putrescine in fungal development.
Topics: Arginine; Fungi; Methionine; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Spores, Fungal | 1979 |
Polyamines in mammalian liver during growth and development.
Topics: Animals; Chick Embryo; Hormones; Humans; Liver; Liver Neoplasms; Liver Regeneration; Mammals; Ornithine; Pharmacology; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1976 |
Some roles of polyamines in microbial physiology.
Topics: Binding Sites; DNA; Escherichia coli; Haemophilus; Mutation; Ornithine; Polyamines; Potassium; Putrescine; RNA; RNA, Bacterial; Saccharomyces cerevisiae; Sodium; Spermidine; Time Factors | 1972 |
The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues.
Topics: Animals; Carboxy-Lyases; DNA-Directed RNA Polymerases; Drug Synergism; Humans; Neoplasms; Ornithine; Polyamines; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Spermine; Xenopus | 1973 |
Regulation of amino acid decarboxylation.
Topics: Amino Acids; Animals; Arginine; Biogenic Amines; Carboxy-Lyases; Diamines; Enzyme Activation; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lysine; Organ Specificity; Ornithine; Pimelic Acids; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 1974 |
Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines.
Topics: Acylation; Amidines; Amine Oxidase (Copper-Containing); Animals; Arginine; Bacteria; Carboxy-Lyases; Escherichia coli; Fungi; Ornithine; Plants; Polyamines; Propylamines; Putrescine; Rats; RNA; Spermidine; Spermine; Transferases; Ureohydrolases; Viruses | 1972 |
On the role of GABA in vertebrate polyamine metabolism.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Kinetics; Liver; Mice; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Trout | 1980 |
Polyamine metabolism and function.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Division; Eflornithine; Humans; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine | 1982 |
Polyamines in the male reproductive system.
Topics: Acetyltransferases; Animals; Biogenic Polyamines; Cricetinae; Epididymis; Humans; Male; Mammals; Mesocricetus; Mice; Ornithine; Prostate; Putrescine; Rats; Semen; Seminal Vesicles; Spermidine; Spermine; Testis | 1996 |
Aliphatic polyamines in physiology and diseases.
Topics: Agmatine; Animals; Disease Models, Animal; Humans; Neoplasms; Ornithine; Putrescine; Spermidine; Spermine | 2014 |
231 other study(ies) available for ornithine and spermidine
| Article | Year |
|---|---|
Analogues of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site.
Topics: Animals; Binding Sites; Carboxy-Lyases; Cattle; In Vitro Techniques; Liver; Male; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prostate; Rats; Structure-Activity Relationship | 1978 |
Axonal transport of polyamines: a reappraisal.
Topics: Animals; Axonal Transport; Male; Ornithine; Polyamines; Putrescine; Rats; Sciatic Nerve; Spermidine; Spinal Cord | 1979 |
Cell cycle specific fluctuations in adenosine 3':5'-cyclic monophosphate and polyamines of Chinese hamster cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Line; Cricetinae; Cyclic AMP; Ornithine; Ornithine Decarboxylase; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Time Factors | 1975 |
Regulation of casein synthesis by polyamines in mammary gland explants of mice.
Topics: Animals; Arginine; Caseins; Cyclic AMP; Cyclic GMP; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Phospholipases; Polyamines; Prolactin; Prostaglandins F; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic | 1977 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Liver Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Polyamine metabolism in MRC5 cells infected with different herpesviruses.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Fibroblasts; Herpesviridae; Humans; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Virus Replication | 1979 |
Polyamine auxotrophs of Saccharomyces cerevisiae.
Topics: Adenosylmethionine Decarboxylase; Genes; Genetic Complementation Test; Genetic Linkage; Ornithine; Ornithine Decarboxylase; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1978 |
Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues.
Topics: Animals; Carboxy-Lyases; Male; Organ Size; Organ Specificity; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Putrescine; Rats; Spermidine; Spermine; Testis; Thymus Gland | 1979 |
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Depression, Chemical; Dose-Response Relationship, Drug; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1979 |
Effects of ultraviolet light on epidermal polyamine metabolism.
Topics: Animals; DNA; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Skin; Spermidine; Spermine; Thymidine; Ultraviolet Rays | 1979 |
Polyamines in mammalian biology and medicine.
Topics: Adenosylmethionine Decarboxylase; Animals; Isoelectric Point; Molecular Conformation; Neoplasms; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; Semen; Sexual Maturation; Spermidine; Spermine; Structure-Activity Relationship | 1979 |
Decreased excretion of polyamines from BHK-21/C13 cells treated with alpha-methylornithine [proceedings].
Topics: Animals; Cell Line; Cricetinae; Kidney; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1979 |
Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Diamines; DNA, Neoplasm; Female; Guanidines; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Time Factors | 1979 |
Synthesis and content of polyamines in bloodstream Trypanosma brucei.
Topics: Amino Acids; Animals; Arginine; Blood; Methionine; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Trypanosoma brucei brucei | 1979 |
Polyamine metabolism in enucleated mouse L-cells.
Topics: Animals; Cell Nucleus; L Cells; Mice; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine | 1977 |
Role of polyamines in cytokinesis of mammalian cells.
Topics: Cell Division; Cell Line; Cytoskeleton; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1979 |
Effect of polyamines and their oxidized derivatives on the metabolism of rat epididymal spermatozoa.
Topics: Adenosine Triphosphate; Animals; Cadaverine; Calcium; Epididymis; Fructose; Glucose; Histamine; Male; Ornithine; Putrescine; Rats; Spermatozoa; Spermidine; Spermine | 1978 |
Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase.
Topics: Carboxy-Lyases; Cell Division; Cell Line; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1978 |
Initial characterization of a HTC cell variant partially resistant to the anti-proliferative effect of ornithine decarboxylase inhibitors.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cell Division; Cell Line; Cell Membrane Permeability; Clone Cells; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1978 |
Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei.
Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Replication; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1978 |
Synthesis of polyamines in the germinating conidia of Aspergillus nidulans.
Topics: Aspergillus nidulans; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Spores, Fungal | 1976 |
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).
Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; DNA Replication; Drug Interactions; Guanidines; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mitoguazone; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1977 |
Ornithine decarboxylase activity and polyamines in relation to aging of human fibroblasts.
Topics: Carboxy-Lyases; Cell Division; Cell Line; Cell Survival; Guanidines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
The role of putrescine in cell proliferation of the skin of mice induced by ethylphenylpropriolate.
Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cell Division; Diamines; DNA; Epidermal Cells; Male; Ornithine; Ornithine Decarboxylase; Propionates; Putrescine; Skin; Spermidine; Spermine | 1977 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism and growth of mouse sarcoma-180.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Depression, Chemical; DNA, Neoplasm; Hydrazines; Liver; Male; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; RNA, Neoplasm; Sarcoma 180; Spermidine; Spermine; Valine | 1976 |
Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.
Topics: Cell Division; Cells, Cultured; DNA Replication; Kinetics; Leucine; Ornithine; Putrescine; Spermidine; Spermine | 1976 |
A new pathway for the biosynthesis of spermidine.
Topics: Anaerobiosis; Arginine; Aspartic Acid; Fumarates; Light; Methionine; Ornithine; Paracoccus denitrificans; Putrescine; Rhodobacter sphaeroides; Spermidine | 1976 |
Canavanine-mediated depletion of polyamine pools in Escherichia coli: effect of head morphogenesis and DNA synthesis.
Topics: Arginine; Canavanine; Coliphages; DNA Viruses; DNA, Viral; Escherichia coli; Micropore Filters; Morphogenesis; Ornithine; Polyamines; Putrescine; Spermidine; Stereoisomerism; Thymine; Tritium; Virus Replication | 1975 |
Occurrence of polyamines in coliphages T5, phiX174 and in phage-infected bacteria.
Topics: Carboxy-Lyases; Coliphages; Dansyl Compounds; DNA Viruses; DNA, Bacterial; DNA, Viral; Escherichia coli; Ornithine; Phosphates; Polyamines; Putrescine; Spermidine | 1975 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism in isoproterenol-stimulated mouse parotid glands.
Topics: Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Carboxy-Lyases; DNA; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Mice; Mitoguazone; Mitosis; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Parotid Gland; Polyamines; Putrescine; RNA; Spermidine; Spermine; Stimulation, Chemical; Valine | 1975 |
Polyamines in vaccinia virions and polypeptides released from viral cores by acid extraction.
Topics: Arginine; HeLa Cells; Ornithine; Peptides; Polyamines; Spermidine; Spermine; Sulfuric Acids; Vaccinia; Vaccinia virus; Viral Proteins | 1975 |
Metabolism of polyamines in mouse neuroblastoma cells in culture: formation of GABA and putreanine.
Topics: Aminobutyrates; Cell Line; gamma-Aminobutyric Acid; Neuroblastoma; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1975 |
Altered tissue polyamine levels due to ornithine-alpha-ketoglutarate in traumatized growing rats.
Topics: Acetylation; Animals; Femur; Food, Fortified; Intestines; Liver; Male; Muscles; Ornithine; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine | 1992 |
Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter.
Topics: Animals; Biological Transport; Hydrogen-Ion Concentration; Kinetics; Lysine; Membrane Potentials; Mitochondria, Liver; Ornithine; Putrescine; Rats; Spermidine; Spermine; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Thermodynamics | 1992 |
Polyamines modulate events mediated by the N-methyl-D-aspartate (NMDA) receptor complex through an ifenprodil-insensitive pathway: in vivo measurements of cyclic GMP in the cerebellum.
Topics: Animals; Biogenic Polyamines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Injections, Intraventricular; Male; Methamphetamine; Mice; Neural Pathways; Ornithine; Pentylenetetrazole; Piperidines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Polyamine influences on the prolactin stimulation of phosphoprotein synthesis in hydroxyurea synchronized MCF-7 human mammary epithelial cells.
Topics: Cell Cycle; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Female; G1 Phase; Humans; Hydroxyurea; Insulin; Interphase; Leucine; Ornithine; Phosphoproteins; Polyamines; Prolactin; Protein Processing, Post-Translational; Putrescine; S Phase; Spermidine; Tritium | 1991 |
Leishmania infantum: polyamine biosynthesis and levels during the growth of promastigotes.
Topics: Animals; Decarboxylation; Diminazene; Dogs; Eflornithine; Leishmania donovani; Methionine; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Trypanocidal Agents | 1991 |
Polyamine metabolism in Pneumocystis carinii.
Topics: Animals; Arginine; Eflornithine; Lung; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentamidine; Pneumocystis; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1991 |
Early developmental profile of ornithine decarboxylase in the frog, Microhyla ornata and its regulation by polyamines.
Topics: Animals; Embryo, Nonmammalian; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Ranidae; Spermidine | 1991 |
Arginine metabolism in rat enterocytes.
Topics: Animals; Arginine; Citrulline; Female; Intestinal Mucosa; Ornithine; Oxidation-Reduction; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Urea | 1991 |
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Carcinoma; Eflornithine; Estrogens; Humans; Male; Mitoguazone; Neoplasm Metastasis; Ornithine; Ornithine Decarboxylase Inhibitors; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Putrescine; Rats; Spermidine; Spermine | 1985 |
Polyamine metabolism in an obligately alkalophilic Bacillus alcalophilus that grows at pH 11.0.
Topics: Arginine; Bacillus; Biological Transport, Active; Chromatography, High Pressure Liquid; Escherichia coli; Gramicidin; Hydrogen-Ion Concentration; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Sodium; Spermidine; Spermine; Valinomycin | 1988 |
Characterization of difluoromethylornithine-resistant mouse and human tumour cell lines.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Arginase; Cell Line; Drug Resistance; Eflornithine; Humans; Mice; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Tumor Cells, Cultured | 1989 |
Uptake, intracellular binding, and excretion of polyamines during growth of Neurospora crassa.
Topics: Arginase; Arginine; Biological Transport; Cell Membrane; Cell Membrane Permeability; Mutation; Neurospora; Neurospora crassa; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermidine Synthase | 1989 |
Inhibition of L-arginine iminohydrolase (EC 3.5.3.6) from Tetrahymena thermophila by putrescine and spermidine: feedback control of polyamine biosynthesis.
Topics: Animals; Arginine; Feedback; Hydrolases; Ornithine; Putrescine; Spermidine; Tetrahymena | 1989 |
Major pathway for putrescine synthesis induced by 1 alpha,25-dihydroxyvitamin D3 in chick duodenum.
Topics: Acetyltransferases; Animals; Calcitriol; Chickens; Duodenum; In Vitro Techniques; Male; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine | 1989 |
Effects of alpha-difluoromethylornithine on polyamine biosynthesis and tyrosine hydroxylase induction in the adrenal gland of the rat subjected to stress or apomorphine.
Topics: Adrenal Glands; Animals; Apomorphine; Cold Temperature; Eflornithine; Enzyme Induction; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Restraint, Physical; Spermidine; Spermine; Stress, Physiological; Tyrosine 3-Monooxygenase | 1985 |
Evidence against putrescine and polyamines as endogenous mediators of fever.
Topics: Animals; Eflornithine; Endotoxins; Fever; Ornithine; Polyamines; Putrescine; Rabbits; Shigella dysenteriae; Spermidine; Spermine | 1985 |
Plasmodium berghei: inhibitors of ornithine decarboxylase block exoerythrocytic schizogony.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Eflornithine; Erythrocytes; Humans; Liver Neoplasms; Malaria; Mice; Mice, Inbred A; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase Inhibitors; Plasmodium berghei; Primaquine; Spermidine | 1985 |
Effect of 1,3,6-triaminohexane and 1,4,7-triaminoheptane on growth and polyamine metabolism in SV-3T3 cells treated with 2-difluoromethylornithine.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Viral; Eflornithine; Fibroblasts; Heptanes; Hexanes; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Simian virus 40; Spermidine | 1986 |
Relationship between ornithine decarboxylase activity and hexamethylene bisacetamide-induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Clone Cells; Dexamethasone; Eflornithine; Erythrocytes; Interphase; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1986 |
Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.
Topics: Alkynes; Animals; Cell Division; Cells, Cultured; Diamines; Eflornithine; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1986 |
In vivo effects of DL-alpha-difluoromethylornithine on the polyamine and nucleotide phosphate metabolism in P388/S leukemia cells.
Topics: Animals; Cell Line; Eflornithine; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Nucleotides; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1986 |
Selective modulation by alpha-difluoromethylornithine of T-lymphocyte and antibody-mediated cytotoxic responses to mouse tumor allografts.
Topics: Animals; Antibody Formation; Cell Cycle; Cytotoxicity, Immunologic; Eflornithine; Female; Immunization; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Ornithine; Spermidine; Spleen; T-Lymphocytes, Cytotoxic; Time Factors; Transplantation, Homologous | 1986 |
Polyamines in 1 alpha, 25-dihydroxycholecalciferol-induced differentiation of human promyelocytic leukemia cells, HL-60.
Topics: Acetyltransferases; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Eflornithine; Humans; Leukemia, Myeloid; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
Polyamines and growth regulation of cultured human breast cancer cells by 17 beta-oestradiol.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Humans; Insulin; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Tamoxifen | 1986 |
Polyamine biosynthesis in trichomonads.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Culture Media; Eflornithine; Eukaryota; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Trichomonas vaginalis; Tritrichomonas | 1986 |
Putrescine does not mediate the androgen-response in mouse kidney.
Topics: Animals; Eflornithine; Female; Kidney; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; RNA, Messenger; Spermidine; Spermine; Testosterone | 1986 |
Effect of putrescine on the respiration of Trypanosoma brucei brucei.
Topics: Animals; Eflornithine; Magnesium; Male; Mitochondria; Ornithine; Oxygen Consumption; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Trypanosoma brucei brucei | 1986 |
Polyamine-mediated turnover of ornithine decarboxylase in Chinese-hamster ovary cells.
Topics: Animals; Cells, Cultured; Chemical Precipitation; Cricetinae; Cricetulus; Eflornithine; Female; Immunoelectrophoresis; Ornithine; Ornithine Decarboxylase; Ovary; Peptide Fragments; Putrescine; Spermidine | 1986 |
Adjustment of polyamine contents in Escherichia coli.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Escherichia coli; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine | 1988 |
A probable new pathway for the biosynthesis of putrescine in Escherichia coli.
Topics: Arginine; Carboxy-Lyases; Chromatography, Thin Layer; Escherichia coli; Glucose; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Ureohydrolases | 1986 |
Localization and biosynthesis of polyamines in insulin-producing cells.
Topics: Animals; Cells, Cultured; Glucose; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Mice; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
Polyamine metabolism in Acanthamoeba: polyamine content and synthesis of ornithine, putrescine, and diaminopropane.
Topics: Acanthamoeba; Animals; Arginase; Arginine; Citrulline; Diamines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1987 |
Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Eflornithine; Guanidines; Kinetics; Mitochondria; Mitoguazone; Ornithine; Putrescine; Pyruvates; Pyruvic Acid; Rats; Spermidine; Temperature; Time Factors | 1985 |
Inhibition of carcinogenesis by alpha-difluoromethylornithine in heterotopically transplanted rat urinary bladders.
Topics: Animals; Eflornithine; Male; Methylnitrosourea; Ornithine; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
Requirement of spermidine for induction of both heme synthesis and globin transcription in murine erythroleukemia cells.
Topics: Animals; Cell Division; Dexamethasone; Dimethyl Sulfoxide; Eflornithine; Globins; Heme; Leukemia, Erythroblastic, Acute; Mice; Ornithine; Spermidine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1985 |
Biological properties of N4- and N1,N8-spermidine derivatives in cultured L1210 leukemia cells.
Topics: Animals; Cells, Cultured; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Polyamines; Spermidine; Structure-Activity Relationship | 1985 |
Polyamine reutilization and turnover in brain.
Topics: Alkynes; Aminocaproates; Animals; Brain; Brain Chemistry; Eflornithine; Male; Mice; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine; Vigabatrin | 1985 |
Ornithine decarboxylase modification and polyamine-stimulated enzyme inactivation in HTC cells.
Topics: Animals; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Eflornithine; Isoenzymes; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Spermidine | 1985 |
Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cycloheximide; Eflornithine; Half-Life; Immunosorbent Techniques; Kinetics; Liver; Male; Mitoguazone; Molecular Weight; Ornithine; Prostate; Putrescine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
Ornithine decarboxylase of Plasmodium falciparum: a peak-function enzyme and its inhibition by chloroquine.
Topics: Animals; Chloroquine; Drug Interactions; Eflornithine; Hydrogen-Ion Concentration; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plasmodium falciparum; Putrescine; Spermidine | 1985 |
Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells.
Topics: Cell Division; Cell Line; Clone Cells; Eflornithine; Female; Humans; Kinetics; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Altered polyamine metabolism in Chinese hamster cells growing in a defined medium.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood; Cell Count; Cell Division; Cell Line; Cricetinae; Culture Media; Female; Ornithine; Ornithine Decarboxylase; Ovary; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
Depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carboxy-Lyases; Cytidine; Depression, Chemical; Enzyme Repression; Injections, Intraperitoneal; Leukemia L1210; Liver; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Organ Size; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spleen; Triazines | 1973 |
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy.
Topics: Animals; Carboxy-Lyases; Dactinomycin; Depression, Chemical; Electrophoresis, Paper; Hydrocortisone; Hypertrophy; In Vitro Techniques; Kidney; Kidney Diseases; Nephrectomy; Ornithine; Putrescine; Rats; Spermidine; Spermine; Stimulation, Chemical | 1972 |
Ornithine decarboxylase and polyamines in silkmoth pupal tissues: effects of ecdysone and injury.
Topics: Adipose Tissue; Animals; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Dactinomycin; Ecdysone; Female; Insecta; Male; Ornithine; Pupa; Putrescine; Spermidine; Spermine; Time Factors; Wings, Animal | 1973 |
Regulation of ornithine decarboxylase activity by putrescine and spermidine in rat liver.
Topics: Animals; Carboxy-Lyases; Cycloheximide; Female; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Ornithine; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Time Factors; Tyrosine Transaminase | 1974 |
Putrescine metabolizing enzyme activities in some rat tissues during postnatal development.
Topics: Age Factors; Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Female; Intestine, Small; Liver; Ornithine; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spleen; Thymus Gland; Time Factors; Transferases | 1973 |
Effect of methylglyoxal bis(guanylhydrazone) on polyamine metabolism in normal and regenerating rat liver and rat thymus.
Topics: Aldehydes; Amidines; Amine Oxidase (Copper-Containing); Animals; Carbon Radioisotopes; Carboxy-Lyases; Female; Glyoxal; Hydrazones; Kinetics; Lethal Dose 50; Liver; Liver Regeneration; Ornithine; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Thymus Gland | 1973 |
Spermidine biosynthesis during germination and subsequent vegetative growth of Bacillus megaterium spores.
Topics: Arginine; Bacillus megaterium; Canavanine; Carbon Radioisotopes; Carboxy-Lyases; Depression, Chemical; Ornithine; Putrescine; Spermidine; Spermine; Spores, Bacterial; Time Factors; Tritium | 1974 |
Polyamine synthesis during initial phases of stress-induced cardiac hypertrophy.
Topics: Adaptation, Physiological; Animals; Butylamines; Carboxy-Lyases; Cardiomegaly; Heart Ventricles; Methionine; Myocardium; Organ Size; Ornithine; Polyamines; Pulmonary Artery; Pyridoxal Phosphate; Rabbits; RNA; S-Adenosylmethionine; Spermidine; Spermine; Stress, Physiological | 1971 |
Polyamine biogenesis in left ventricle of the rat heart after aortic constriction.
Topics: Animals; Aorta; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cardiomegaly; Constriction; Decarboxylation; Female; Heart Ventricles; Male; Myocardium; Organ Size; Ornithine; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Stress, Mechanical | 1972 |
Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in formation of putrescine, spermidine, and spermine.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Electrophoresis, Paper; Liver; Liver Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Transplantation, Homologous | 1972 |
The polyamine content in two slow-growing rat hepatomas.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Ornithine; Polyamines; Rats; Spermidine; Spermine | 1972 |
Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in untransformed and transformed mouse fibroblasts by serum.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Culture Techniques; Fibroblasts; Kinetics; Mice; Ornithine; Putrescine; Simian virus 40; Spermidine; Spermine; Time Factors; Trypsin | 1974 |
Polyamine biosynthesis and vitamin B6 deficiency. Evidence for pyridoxal phosphate as coenzyme for S-adenosylmethionine decarboxylase.
Topics: Animals; Arginine; Brain; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme Activation; Liver; Male; Organ Specificity; Ornithine; Polyamines; Putrescine; Pyridoxal Phosphate; Rats; S-Adenosylmethionine; Spermidine; Spermine; Ultracentrifugation; Vitamin B 6 Deficiency | 1974 |
Polyamine metabolism in potassium-deficient bacteria.
Topics: Arginine; Bacterial Proteins; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Culture Media; Escherichia coli; Methionine; Mutation; Ornithine; Potassium; Putrescine; RNA, Bacterial; S-Adenosylmethionine; Sodium; Spermidine; Urea | 1972 |
Polyamine requirements of a conditional polyamine auxotroph of Escherichia coli.
Topics: Arginine; Cadaverine; Canavanine; Carbohydrate Metabolism; Carbon Isotopes; Culture Media; Densitometry; Escherichia coli; Glucose; Mutation; Ornithine; Osmolar Concentration; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1973 |
Distinct effects of diamines, polyamines, and magnesium ions on the stability of lambda phage heads.
Topics: Cadaverine; Calcium; Coliphages; DNA, Viral; Drug Stability; Escherichia coli; Lysine; Magnesium; Mutation; Nucleic Acid Conformation; Ornithine; Polyamines; Propylamines; Putrescine; Spermidine; Spermine; Thymidine; Tritium; Viral Proteins | 1973 |
Growth of ribonucleic acid bacteriophage f2 in a conditional putrescine auxotroph of Escherichia coli: evidence for a polyamine role in translation.
Topics: Arginine; Carbon Radioisotopes; Cell-Free System; Coliphages; Culture Media; DNA-Directed RNA Polymerases; Escherichia coli; Leucine; Mutation; Ornithine; Protein Biosynthesis; Putrescine; Rifampin; RNA, Messenger; RNA, Viral; Spermidine; Tritium; Uracil; Viral Proteins | 1974 |
RNA metabolism in isolated perfused normal and regenerating livers: polyamine effects.
Topics: Amino Acids; Animals; Carbon Isotopes; Carboxy-Lyases; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Enzyme Activation; Hepatectomy; In Vitro Techniques; Liver; Liver Regeneration; Ornithine; Orotic Acid; Perfusion; Polyribosomes; Rats; RNA; Spermidine | 1972 |
Polyamine biogenesis in the rat mammary gland during pregnancy and lactation.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Epithelial Cells; Epithelium; Female; Lactation; Mammary Glands, Animal; Ornithine; Polyamines; Pregnancy; Pregnancy, Animal; Putrescine; Rats; Ribonucleases; RNA; Spermidine; Spermine | 1972 |
Hormonal regulation of spermidine formation during spermatogenesis in the rat.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cortisone; Follicle Stimulating Hormone; Growth Hormone; Hydrogen-Ion Concentration; Hypophysectomy; In Vitro Techniques; Luteinizing Hormone; Male; Organ Size; Ornithine; Pituitary Gland; Prolactin; Rats; S-Adenosylmethionine; Spermatogenesis; Spermidine; Testis; Testosterone; Time Factors; Triiodothyronine | 1973 |
Polyamine metabolism in rat liver: effect of starvation and refeeding.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; DNA; Liver; Male; Ornithine; Polyamines; Proteins; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Spermine; Starvation; Time Factors | 1973 |
Effect of thioamide derivatives on induction of ornithine decarboxylase in rat liver.
Topics: Acetamides; Adrenal Glands; Adrenalectomy; Amides; Animals; Carboxy-Lyases; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Induction; Growth Hormone; Hypophysectomy; Liver; Male; Ornithine; Pituitary Gland; Putrescine; Rats; Spermidine; Spermine; Thiourea; Time Factors | 1973 |
Spermine is major polyamine in sea urchins: studies of polyamines and their synthesis in developing sea urchins.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Paper; Electrophoresis; Methionine; Ornithine; Putrescine; Sea Urchins; Spermidine; Spermine | 1973 |
Control of ornithine decarboxylase activity in stimulated human lymphocytes by putrescine and spermidine.
Topics: Blood Proteins; Carbon Isotopes; Carboxy-Lyases; Cells, Cultured; Cycloheximide; DNA; Humans; Lectins; Lymphocytes; Ornithine; Phenylalanine; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Polyamine synthesis and polysome patterns in the rat uterus during the oestrous cycle.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Estrus; Female; Nucleoproteins; Ornithine; Polyamines; Polyribosomes; Pregnancy; Putrescine; Rats; Spermidine; Spermine; Ultracentrifugation; Uterus | 1973 |
Regulation of polyamine synthesis in Physarum polyciphalum during growth and differentiation.
Topics: Carbon Isotopes; Carboxy-Lyases; Cell Differentiation; Culture Media; Cycloheximide; Electrophoresis, Paper; Mitosis; Myxomycetes; Ornithine; Polyamines; Protein Denaturation; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Subcellular Fractions; Time Factors | 1973 |
Synthesis and accumulation of polyamines in rat liver regenerating after treatment with carbon tetrachloride.
Topics: Animals; Carbon Radioisotopes; Carbon Tetrachloride; Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Female; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Ornithine; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Thioacetamide; Time Factors; Transferases | 1973 |
Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-L-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone).
Topics: Adenosine; Amidines; Animals; Carboxy-Lyases; Depression, Chemical; Glyoxal; Hydrazones; Leukemia L1210; Male; Methionine; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine; Stimulation, Chemical | 1973 |
Effects of methylglyoxal-bis(guanylhydrazone) on polyamine metabolism in spleens of mice with disseminated L1210 lymphoid leukemia.
Topics: Amidines; Animals; Antineoplastic Agents; Carboxy-Lyases; Glyoxal; Hydrazones; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Spleen; Time Factors | 1974 |
Regulation of ornithine decarboxylase synthesis. Effect of a nutritional deficiency of vitamin B6.
Topics: Animals; Apoproteins; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dithiothreitol; Liver; Male; Organ Specificity; Ornithine; Putrescine; Pyridoxal Phosphate; Pyridoxine; Rats; Spermidine; Vitamin B 6 Deficiency | 1974 |
Precursors of polyamines in Pseudomonas acidovorans.
Topics: Arginine; Carbon Radioisotopes; Chromatography; Glutamates; Micropore Filters; Ornithine; Polyamines; Pseudomonas; Putrescine; Spermidine | 1974 |
Effect of isoproterenol on polyamine metabolism in mouse salivary glands.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cycloheximide; DNA; Enzyme Induction; Isoproterenol; Male; Methionine; Mice; Organ Size; Ornithine; Parotid Gland; Pilocarpine; Polyamines; Putrescine; RNA; Salivary Glands; Spermidine; Spermine; Stimulation, Chemical; Submandibular Gland; Time Factors; Uridine | 1974 |
Polyamine biosynthesis in human fetal liver and brain.
Topics: Adult; Age Factors; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Female; Fetus; Humans; Liver; Ornithine; Polyamines; Pregnancy; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 1974 |
Arginase affects lactogenesis through its influence on the biosynthesis of spermidine.
Topics: Animals; Arginase; Culture Techniques; Female; Hydrocortisone; Insulin; Lactation; Mammary Glands, Animal; Mice; Milk Proteins; Ornithine; Pregnancy; Prolactin; Spermidine | 1974 |
Polyamine metabolism in mouse liver after partial hepatectomy.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Carboxy-Lyases; Electrophoresis; Escherichia coli; Half-Life; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Methionine; Mice; Ornithine; Polyamines; RNA; S-Adenosylmethionine; Spermidine; Spermine; Time; Transferases | 1971 |
Polyamine synthesis in the regenerating rat liver: stimulation of S-adenosyl methionine decarboxylase, and spermidine and spermine synthases after partial hepatectomy.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Half-Life; Hepatectomy; Kinetics; Liver; Liver Regeneration; Ornithine; Polyamines; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Transferases | 1972 |
Polyamines in the developing rat and in supportive tissues.
Topics: Amniotic Fluid; Animals; Carboxy-Lyases; Embryo, Mammalian; Female; Fetus; Gestational Age; Histidine; Liver; Ornithine; Polyamines; Pregnancy; Rats; Rats, Inbred Strains; RNA; S-Adenosylmethionine; Spermidine; Spermine; Uterus | 1972 |
Ornithine decarboxylase activity in synchronously growing Don C cells.
Topics: Animals; Anti-Bacterial Agents; Benzocycloheptenes; Carbon Isotopes; Carboxy-Lyases; Cell Line; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; DNA; Leucine; Lung; Ornithine; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine; Thymidine; Tritium; Uridine | 1972 |
Studies on the biosynthesis of sym-homospermidine in sandal (Santalum album L.).
Topics: Aldehydes; Amidines; Arginine; Autoradiography; Carbon Isotopes; Chromatography, Paper; Glutamates; Ornithine; Oxidation-Reduction; Plants; Polyamines; Putrescine; Spermidine | 1972 |
Effects of methotrexate and cytosine arabinoside on polyamine metabolism in a mouse L1210 leukemia.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cytarabine; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Spleen | 1972 |
Ornithine decarboxylase activity and the accumulation of putrescine at early stages of liver regeneration.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cytosol; Female; Liver; Liver Regeneration; Ornithine; Proteins; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Time Factors | 1972 |
Studies on the metabolism of sym-homospermidine in sandal (Santalum albumin L.).
Topics: Arginine; Carbon Isotopes; Ornithine; Plants; Spermidine; Spermine; Tritium | 1972 |
Drug stimulation of putrescine and spermidine syntheses. Relationships to enhancement of ribonucleic acid synthesis.
Topics: Animals; Benzopyrenes; Carboxy-Lyases; Clofibrate; Cycloheximide; Heparin; Liver; Male; Methylcholanthrene; Ornithine; Phenobarbital; Polyamines; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Stimulation, Chemical; Tritium; Uridine | 1971 |
Compartmentalization of spermine and spermidine in the herpes simplex virion.
Topics: Carcinoma; Cell Line; Detergents; DNA, Viral; Herpes Simplex; Herpesviridae; Humans; Ornithine; Polyamines; Protein Binding; Skin; Spermidine; Spermine; Time Factors; Tritium; Urea | 1971 |
Methylglyoxal BIS (guanylhydrazone) and alpha-difluoromethylornithine-induced polyamine deprivation in psoriatic lesions.
Topics: Carboxy-Lyases; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Humans; Injections, Intradermal; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1982 |
Efficacy of combinations of difluoromethylornithine and bleomycin in a mouse model of central nervous system African trypanosomiasis.
Topics: Animals; Bleomycin; Central Nervous System Diseases; Disease Models, Animal; Drug Therapy, Combination; Eflornithine; Female; Male; Mice; Ornithine; Spermidine; Spermine; Trypanocidal Agents; Trypanosomiasis, African | 1983 |
Effect of polyamine antimetabolites on cultured human keratinocytes from normal and uninvolved psoriatic skin.
Topics: Antimetabolites; Cell Division; Cells, Cultured; DNA; Eflornithine; Guanidines; Humans; Keratins; Mitoguazone; Ornithine; Protein Biosynthesis; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1984 |
Compartmentation of spermidine in Neurospora crassa.
Topics: Carbon Radioisotopes; Kinetics; Neurospora; Neurospora crassa; Ornithine; Putrescine; Spermidine; Spermine; Subcellular Fractions | 1983 |
Temperature-dependent and transformation-associated changes in polyamine metabolism in normal and Rous sarcoma virus-infected chick embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Eflornithine; Fibroblasts; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine; Temperature | 1981 |
Role of polyamines in the proliferation and steroidogenic activities of bovine adrenocortical cells in culture.
Topics: Adrenal Cortex; Animals; Carboxy-Lyases; Cattle; Cell Division; Cells, Cultured; Cosyntropin; Cyclic AMP; Eflornithine; Hydrocortisone; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1981 |
Inhibitors of polyamine biosynthesis block human cytomegalovirus replication.
Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Eflornithine; Guanidines; Humans; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine; Virus Replication | 1982 |
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Eflornithine; Interphase; Lymphoma; Mice; Models, Biological; Ornithine; Ornithine Decarboxylase; Polyamines; Protein Kinases; Putrescine; Spermidine | 1983 |
D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.
Topics: Cells, Cultured; Cytomegalovirus; DNA, Viral; Eflornithine; Humans; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine; Viral Proteins; Virion; Virus Replication | 1984 |
Radiochemical determination of polyamines in poliovirus and human rhinovirus 14.
Topics: Eflornithine; HeLa Cells; Humans; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Poliovirus; Putrescine; Rhinovirus; Spermidine; Spermine | 1984 |
Activation of ADP-ribosyltransferase in polyamine-depleted mammalian cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Centrifugation, Density Gradient; Chromatography; Cricetinae; DNA; Enzyme Activation; Fibroblasts; Kidney; Mitoguazone; Nucleotidyltransferases; Ornithine; Poly(ADP-ribose) Polymerases; Spermidine; Spermine | 1984 |
Inhibition of growth of Giardia lamblia by difluoromethylornithine, a specific inhibitor of polyamine biosynthesis.
Topics: Animals; Eflornithine; Entamoeba histolytica; Giardia; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Trichomonas vaginalis | 1984 |
Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; DNA, Neoplasm; Eflornithine; Molecular Conformation; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Viscosity | 1983 |
Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Survival; Eflornithine; Fluorouracil; Humans; Kinetics; Ornithine; Putrescine; Spermidine | 1983 |
Inhibition of DNA and protein synthesis in UV-irradiated mouse skin by 2-difluoromethylornithine, methylglyoxal bis(guanylhydrazone), and their combination.
Topics: Animals; DNA Replication; Drug Interactions; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Protein Biosynthesis; Putrescine; Skin; Spermidine; Ultraviolet Rays | 1983 |
Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation.
Topics: Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Eflornithine; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Teratoma | 1983 |
Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an orn
Topics: Aged; Cadaverine; Chromatography, High Pressure Liquid; Eflornithine; Female; Fluorescence; Humans; Male; Middle Aged; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Differential effect of alpha-difluoromethylornithine on the in vivo uptake of 14C-labeled polyamines and methylglyoxal bis(guanylhydrazone) by a rat prostate-derived tumor.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Eflornithine; Guanidines; Male; Mitoguazone; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Rats; Rats, Inbred Strains; Spermidine | 1984 |
Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Eflornithine; Fibroblasts; Mice; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Diazepam; Dimethyl Sulfoxide; Eflornithine; Kinetics; Leukemia, Experimental; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Inhibition of platelet aggregation and endogenous lectin activity by oligoamines.
Topics: Amino Acids; Animals; Cattle; Dose-Response Relationship, Drug; Hemagglutination Tests; Histidine; Humans; Lectins; Lysine; Ornithine; Platelet Aggregation; Putrescine; Serotonin; Spermidine; Spermine; Thrombin | 1984 |
Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells.
Topics: Animals; Cell Division; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Eflornithine; Liver Neoplasms, Experimental; Macromolecular Substances; Neoplasm Proteins; Ornithine; Polyribosomes; Putrescine; Rats; Spermidine; Spermine | 1984 |
Involvement of spermidine in proliferation and differentiation of human promyelocytic leukemia cells.
Topics: Acetamides; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Humans; Leukemia, Myeloid, Acute; Ornithine; Putrescine; Spermidine; Spermine | 1984 |
Time dependence of the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity caused by alpha-difluoromethylornithine-induced polyamine depletion in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Drug Synergism; Eflornithine; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine | 1984 |
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Polyamines as mediators of estrogen action on the growth of experimental breast cancer in rats.
Topics: Animals; Cell Aggregation; Eflornithine; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).
Topics: Animals; Cells, Cultured; Eflornithine; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Spermidine; Time Factors | 1984 |
Polyamine requirements for induction of HL-60 promyelocyte differentiation by leukocyte-conditioned medium and phorbol ester.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Line; Culture Media; Eflornithine; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Spermidine; Tetradecanoylphorbol Acetate | 1984 |
Polyamine biosynthetic enzymes as targets in cancer chemotherapy.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Enzyme Inhibitors; Methionine; Mice; Ornithine; Putrescine; Spermidine; Spermine; Teratoma | 1984 |
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
Topics: Animals; Animals, Newborn; Brain; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine; Female; Heart; Male; Myocardium; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermidine Synthase; Spermine; Transferases | 1984 |
Physiological effects in bovine lymphocytes of inhibiting polyamine synthesis with ethylglyoxal bis(guanylhydrazone).
Topics: Animals; Aphidicolin; Cattle; Cycloheximide; Diterpenes; DNA Replication; Eflornithine; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Biosynthesis; Proteins; Spermidine | 1984 |
Polyamines and the development of monocrotaline-induced pulmonary hypertension.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood Pressure; Eflornithine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kinetics; Lung; Male; Monocrotaline; Ornithine; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Spermidine; Spermine | 1984 |
Treatment with alpha-difluoromethylornithine plus a spermidine analog leads to spermine depletion and growth inhibition in cultured L1210 leukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Leukemia L1210; Mice; Ornithine; Spermidine; Spermine | 1984 |
The role of polyamine depletion and accumulation of decarboxylated S-adenosylmethionine in the inhibition of growth of SV-3T3 cells treated with alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Diamines; Eflornithine; Fibroblasts; Mice; Mice, Inbred Strains; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine | 1984 |
Polyamines and pancreatic growth induced by caerulein.
Topics: Animals; Ceruletide; DNA; Eflornithine; Male; Organ Size; Ornithine; Pancreas; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
Regulation of polyamine synthesis in relation to putrescine and spermidine pools in Neurospora crassa.
Topics: Arginine; Kinetics; Neurospora; Neurospora crassa; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1981 |
Metabolic sequestration of putrescine in Neurospora crassa.
Topics: Carbon Radioisotopes; Kinetics; Neurospora; Neurospora crassa; Ornithine; Putrescine; Radioisotope Dilution Technique; Spermidine; Spermine | 1982 |
Biosynthesis of the spermidine and guanidino units in the glycocinnamoylspermidine antibiotic cinodine.
Topics: Aminoglycosides; Anti-Bacterial Agents; Arginine; Citrulline; Guanidines; Ornithine; Spermidine | 1984 |
Periimplantation-like growth and development of mouse blastocysts in medium containing horse serum.
Topics: Animals; Blastocyst; Blood; Cattle; Culture Media; Embryo Implantation; Female; Fetal Blood; Horses; Mice; Mice, Inbred ICR; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine | 1984 |
Inhibition of polyamine synthesis and proliferation in mouse L cells by DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Deoxyadenine Nucleotides; DNA; L Cells; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Thymine Nucleotides | 1983 |
Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.
Topics: Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cell Division; Eflornithine; Kinetics; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1980 |
Polyamine depletion induces enhanced synthesis and accumulation of cadaverine in cultured Ehrlich ascites carcinoma cells.
Topics: Animals; Cadaverine; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cells, Cultured; Diamines; Eflornithine; Female; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1980 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines; Putrescine; Radiation Tolerance; Rats; Spermidine; Spermine; X-Rays | 1980 |
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Interphase; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1981 |
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Ovulation; Pregnancy; Putrescine; Rats; Spermidine; Spermine | 1980 |
Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Mitoguazone; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1980 |
Selective killing of transformed cells in combination with inhibitors of polyamine biosynthesis and S-phase specific drugs.
Topics: Cell Division; Cell Transformation, Neoplastic; Cytarabine; Drug Synergism; Eflornithine; HeLa Cells; Humans; Interphase; Ornithine; Polyamines; Spermidine; Spermine | 1981 |
Polyamines are needed for the differentiation of 3T3-L1 fibroblasts into adipose cells.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Eflornithine; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine | 1981 |
Indirect evidence for a strict negative control of S-adenosyl-L-methionine decarboxylase by spermidine in rat hepatoma cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Cell Line; Eflornithine; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Spermidine | 1981 |
Formation and interconversion of putrescine and spermidine in mammalian cells.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Cell Line; Eflornithine; Enzyme Activation; Enzyme Repression; Liver; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine | 1980 |
Effects of inhibitors of ornithine and S-adenosylmethionine decarboxylases on L6 myoblast proliferation.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Eflornithine; Mitoguazone; Muscles; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1982 |
Effect of epidermal polyamine depletion on the accumulation of methylglyoxal bis(guanylhydrazone) in mouse skin.
Topics: Animals; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Polyamines; Putrescine; Skin; Skin Physiological Phenomena; Spermidine | 1982 |
Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Iodoacetates; Iodoacetic Acid; Mice; Mitoguazone; Neoplasms, Experimental; Ornithine; Ouabain; Polyamines; Putrescine; Spermidine | 1981 |
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1982 |
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
Topics: Animals; Animals, Newborn; Brain; Carboxy-Lyases; Eflornithine; Female; Heart; Kidney; Myocardium; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Polyamine depletion influences drug-induced chromosomal damage.
Topics: Animals; Carmustine; Chromosomes; Cisplatin; DNA; Eflornithine; Nucleic Acid Conformation; Ornithine; Polyamines; Putrescine; Rats; Sister Chromatid Exchange; Spermidine; Spermine | 1982 |
Combined topical use of difluoromethyl ornithine and methylglyoxal bis (guanylhydrazone) in UV-irradiated mouse skin.
Topics: Adenosylmethionine Decarboxylase; Animals; Eflornithine; Female; Guanidines; Male; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Skin; Spermidine; Ultraviolet Rays | 1982 |
Polyamine cytochemistry. Use of a novel o-phtalaldehyde method for visualizing spermidine and spermine. Comparisons to the formaldehyde-fluorescamine method.
Topics: Aldehydes; Animals; Cats; Eflornithine; Fluorescamine; Formaldehyde; Histocytochemistry; Hydrogen-Ion Concentration; Methods; o-Phthalaldehyde; Ornithine; Polyamines; Rats; Spermidine; Spermine; Spiro Compounds | 1982 |
Role of polyamines in expression of the differentiated phenotype of chondrocytes: effect of DL-alpha-hydrazino-delta-aminovaleric acid (DL-HAVA), an inhibitor of ornithine decarboxylase, on chondrocytes treated with parathyroid hormone.
Topics: Animals; Carboxy-Lyases; Cartilage; Cell Differentiation; Cells, Cultured; DNA Replication; Kinetics; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Parathyroid Hormone; Peptide Fragments; Polyamines; Putrescine; Rabbits; Spermidine; Spermine; Teriparatide | 1983 |
Regulation of tRNA methyltransferase activities by spermidine and putrescine. Inhibition of polyamine synthesis and tRNA methylation by alpha-methylornithine or 1,3-diaminopropan-2-ol in Dictyostelium.
Topics: Diamines; Dictyostelium; Methylation; Nucleosides; Ornithine; Propanolamines; Putrescine; RNA, Transfer; Spermidine; tRNA Methyltransferases | 1982 |
Affinity of putrescine, spermidine and spermine for pigmented tissues.
Topics: Animals; Cattle; Eye; Kidney; Liver; Male; Melanins; Melanocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Putrescine; Species Specificity; Spermidine; Spermine; Tissue Distribution | 1982 |
Induction of polyamine limitation in Chinese hamster ovary cells by alpha-methylornithine.
Topics: Animals; Cell Division; Cricetinae; Cricetulus; Female; Ornithine; Ovary; Polyamines; Putrescine; Spermidine | 1981 |
Putrescine turnover in kidneys of testosterone-treated mice.
Topics: Animals; Cadaverine; Castration; Guanidines; Kidney; Male; Mice; Organ Size; Ornithine; Putrescine; Spermidine; Testosterone | 1981 |
A possible role of arginase in the regulation of polyamine biosynthesis in the rat thyroid.
Topics: Amino Acids; Animals; Arginase; Arginine; DNA; Male; Methylthiouracil; Ornithine; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1981 |
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Inhibition of Dugesia tigrina auricle regeneration by inhibitors of polyamine synthesis.
Topics: Aldehydes; Animals; Ornithine; Polyamines; Putrescine; Pyruvaldehyde; Regeneration; Spermidine; Spermine; Turbellaria | 1980 |
Polyamine metabolism in the rat liver after orthotopic liver transplantation.
Topics: Acetyltransferases; Alanine Transaminase; Animals; Aspartate Aminotransferases; DNA; Genes, myc; Graft Survival; Kinetics; L-Lactate Dehydrogenase; Liver; Liver Transplantation; Male; Malondialdehyde; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine | 1995 |
Use of 4-fluoro-L-ornithine to monitor metabolic flux through the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; Cell Membrane Permeability; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Humans; Kinetics; Leukemia L1210; Melanoma; Mice; Ornithine; Ornithine Decarboxylase; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Transglutaminase activity in enterocytes isolated from pig jejunum.
Topics: Animals; Arginine; Calcium; Cell Separation; Glutamine; Glycine; Jejunum; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Swine; Temperature; Transglutaminases | 1995 |
Selective putrescine export is regulated by insulin and ornithine in Reuber H35 hepatoma cells.
Topics: Animals; Biological Transport; Culture Media; Insulin; Liver Neoplasms, Experimental; Ornithine; Putrescine; Rats; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Verapamil | 1994 |
Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines.
Topics: Animals; Brain; Diamines; Gene Expression; Male; Mice; Mice, Transgenic; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Polyamines; Putrescine; Spermidine; Spermine; Testis | 1993 |
Polyamine changes in the vestibular nuclei of guinea pigs following labyrinthectomy.
Topics: Amino Acids; Animals; Brain Stem; Chromatography, High Pressure Liquid; Ear, Inner; Guinea Pigs; Image Processing, Computer-Assisted; Ornithine; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vestibular Nuclei | 1994 |
Astrocytes, not neurons, show most prominent staining for spermidine/spermine-like immunoreactivity in adult rat brain.
Topics: Animals; Antibody Specificity; Arginine; Astrocytes; Brain; Brain Chemistry; Enzyme-Linked Immunosorbent Assay; Ethanolamine; Ethanolamines; Female; Histamine; Immunohistochemistry; Lysine; Male; Neurons; Ornithine; Putrescine; Rats; Rats, Inbred Lew; Spermidine | 1997 |
Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export.
Topics: Amine Oxidase (Copper-Containing); Animals; Biological Transport; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Drug Resistance; Drug Tolerance; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1997 |
Enteral supplementation with ornithine alpha ketoglutarate improves the early adaptive response to resection.
Topics: Adaptation, Biological; Animals; Blotting, Northern; Caseins; Enteral Nutrition; Food, Fortified; Hyperplasia; Ileum; Jejunostomy; Male; Ornithine; Postoperative Period; Protein Hydrolysates; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine; Sucrase | 1997 |
Nutritional efficacy of a spermidine supplemented diet.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Brain Chemistry; Dietary Supplements; Eating; Glutamine; Growth; Liver; Male; Muscle, Skeletal; Nitrogen; Ornithine; Polyamines; Rats; Rats, Sprague-Dawley; Spermidine | 1997 |
Polyamine metabolism in the thermotolerant mesophilic fungus Aspergillus fumigatus.
Topics: Adenosylmethionine Decarboxylase; Aspergillus fumigatus; Cadaverine; Carboxy-Lyases; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Temperature | 1997 |
Metabolism of polyamines in transgenic cells of carrot expressing a mouse ornithine decarboxylase cDNA.
Topics: Animals; Arginine; Biological Transport; Cell Line; Daucus carota; DNA, Complementary; Mice; Ornithine; Ornithine Decarboxylase; Plants, Genetically Modified; Polyamines; Putrescine; Recombinant Proteins; Spermidine; Spermine; Transfection | 1998 |
Effects of L-valine on growth and polyamine metabolism in human colon carcinoma cells.
Topics: Arginine; Cell Differentiation; Cell Division; Cell Survival; Glutamine; HT29 Cells; Humans; Ornithine; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Valine | 1998 |
NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
Topics: Animals; Aorta; Arginase; Arginine; Caco-2 Cells; Cell Division; Coculture Techniques; DNA; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Donors; Ornithine; Ornithine Decarboxylase; Oxadiazoles; Polyamines; Putrescine; Quinoxalines; Rats; Spermidine; Spermine; Thymidine; Triazenes; Urea | 1998 |
Allosteric regulation in Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase revisited: association of concerted homotropic cooperative interactions and local heterotropic effects.
Topics: Adenosine Monophosphate; Allosteric Regulation; Amino Acid Sequence; Arsenates; Bacterial Proteins; Binding, Competitive; Diphosphates; Enzyme Activation; Enzyme Repression; Escherichia coli Proteins; Kinetics; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Protein Kinases; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Spermidine | 1998 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body Weight; Cell Division; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Colonic Polyps; Disease Progression; Fasting; Hyperplasia; Male; Neoplasm Proteins; Ornithine; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Putrescine; Rats; Rats, Wistar; Sensitivity and Specificity; Spermidine; Spermine | 2000 |
Antifungal activity of three spermidine conjugates.
Topics: Antifungal Agents; Ascomycota; Avena; Culture Media; Food Microbiology; Hordeum; Ornithine; Pollen; Putrescine; Spermidine; Spermine | 2001 |
Activities of arginase I and II are limiting for endothelial cell proliferation.
Topics: Animals; Arginase; Cattle; Cell Division; Cells, Cultured; Coronary Vessels; Eflornithine; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Isoenzymes; Lac Operon; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Transfection | 2002 |
Genetic manipulation of the metabolism of polyamines in poplar cells. The regulation of putrescine catabolism.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amine Oxidase (Copper-Containing); Animals; Carbon Radioisotopes; Cell Line; Glutamate Decarboxylase; Mice; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Plants, Genetically Modified; Polyamines; Putrescine; Salicaceae; Spermidine | 2002 |
Polyamine participation in the maturation of glycoprotein fucosylation, but not sialylation, in rat small intestine.
Topics: Amine Oxidase (Copper-Containing); Animal Feed; Animals; Animals, Suckling; beta-D-Galactoside alpha 2-6-Sialyltransferase; Enzyme Induction; Enzyme Inhibitors; Glycoproteins; Glycosylation; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Milk; Ornithine; Protein Processing, Post-Translational; Proteins; Putrescine; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Sialyltransferases; Spermidine; Spermine; Transcription, Genetic; Weaning | 2002 |
Comparative uptake of polyamines by prostate and non-prostate cancer cell lines.
Topics: Animals; Breast Neoplasms; Carbon Radioisotopes; Humans; Male; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats; Reproducibility of Results; Sensitivity and Specificity; Spermidine; Spermine; Tumor Cells, Cultured; Urogenital Neoplasms | 2002 |
STUDIES ON THE DETERMINATION OF SPERMIDINE AND SPERMINE AND THEIR METABOLISM IN THE DEVELOPING CHICK EMBRYO.
Topics: Amines; Animals; Autoradiography; Carbon Isotopes; Chick Embryo; Chromatography; Coloring Agents; Electrophoresis; Ethionine; Histocytochemistry; Liver; Metabolism; Methionine; Ornithine; Rats; Research; Spermidine; Spermine; Staining and Labeling | 1963 |
Endogenous polyamine levels in macrophages is sufficient to support growth of Toxoplasma gondii.
Topics: Animals; Carboxy-Lyases; Cells, Cultured; Chlorocebus aethiops; Host-Parasite Interactions; Macrophages, Peritoneal; Male; Mice; Nitric Oxide; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Toxoplasma; Vero Cells | 2004 |
Polyamine synthesis from proline in the developing porcine placenta.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Female; Fetal Development; Male; Methionine; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Placentation; Polyamines; Pregnancy; Proline; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Sus scrofa | 2005 |
eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
Topics: Aminoquinolines; Animals; Arginine; Calcium; Carbazoles; Carcinoma, Hepatocellular; Cell Enlargement; Cell Proliferation; Chromogranin A; Chromogranins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA; Enzyme Inhibitors; Guanylate Cyclase; Indoles; Isoenzymes; Leucine; Liver; MAP Kinase Signaling System; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Ornithine; Pancreatic Hormones; Peptides; Phospholipase C beta; Protein Isoforms; Rats; Receptors, Atrial Natriuretic Factor; Spermidine; Thymidine; Time Factors; Type C Phospholipases | 2005 |
Putrescine accumulation in wine: role of Oenococcus oeni.
Topics: Gram-Positive Cocci; Ornithine; Putrescine; Spermidine; Wine | 2005 |
Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA).
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Biogenic Polyamines; Liver; Liver Transplantation; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Putrescine; Rats; Rats, Inbred Lew; Reperfusion Injury; Spermidine; Spermine | 2007 |
Divergent polyamine metabolism in the Apicomplexa.
Topics: Animals; Apicomplexa; Arginine; Carbamyl Phosphate; Citrulline; Fibroblasts; Foreskin; Genome, Protozoan; Humans; Male; Ornithine; Polyamines; Putrescine; Spermidine; Toxoplasma | 2007 |
Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells.
Topics: Animals; Cationic Amino Acid Transporter 1; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibitors; Epithelial Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ornithine-Oxo-Acid Transaminase; Pigment Epithelium of Eye; Proto-Oncogene Proteins c-myc; Putrescine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermidine; Spermine; Swine; Telomerase; Time Factors; Transfection; Up-Regulation | 2007 |
Transgenic manipulation of a single polyamine in poplar cells affects the accumulation of all amino acids.
Topics: Amino Acids; Animals; Carbon; Cell Line; gamma-Aminobutyric Acid; Mice; Nitrogen; Ornithine; Ornithine Decarboxylase; Perchlorates; Plants, Genetically Modified; Populus; Putrescine; Solubility; Spermidine; Spermine; Statistics as Topic; Time Factors; Transgenes; Up-Regulation | 2010 |
Central L-ornithine, but not polyamines, induces a hypnotic effect in neonatal chicks under acute stress.
Topics: Animals; Behavior, Animal; Chickens; Hypnotics and Sedatives; Injections, Intraventricular; Male; Ornithine; Polyamines; Posture; Putrescine; Social Isolation; Spermidine; Spermine; Stress, Psychological; Time Factors; Vocalization, Animal | 2010 |
Life without putrescine: disruption of the gene-encoding polyamine oxidase in Ustilago maydis odc mutants.
Topics: Gene Knockout Techniques; Genes, Fungal; Microbial Viability; Mutagenesis, Insertional; Ornithine; Osmotic Pressure; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Stress, Physiological; Ustilago; Virulence | 2010 |
Polyamines are traps for reactive intermediates in furan metabolism.
Topics: Acetylcysteine; Aldehydes; Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Environmental Pollution; Furans; Glutamine; Glutathione; Hepatocytes; Humans; Liver; Lysine; Mass Spectrometry; Ornithine; Oxidation-Reduction; Putrescine; Pyrroles; Rats; Spermidine | 2011 |
Ornithine: the overlooked molecule in the regulation of polyamine metabolism.
Topics: Animals; Arabidopsis; Biosynthetic Pathways; Cadaverine; Carbon Isotopes; Carboxy-Lyases; DNA, Complementary; Genetic Vectors; Mice; Ornithine; Ornithine Decarboxylase; Plants, Genetically Modified; Polyamines; Putrescine; Radioactivity; Spermidine; Spermine | 2013 |
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses.
Topics: Agmatine; Animals; Carboxy-Lyases; Cationic Amino Acid Transporter 1; Citrulline; Embryo Implantation; Embryonic Development; Female; Mammals; Nitric Oxide Synthase Type III; Ornithine; Ornithine Decarboxylase; Pregnancy; Pregnancy, Animal; Putrescine; Sheep; Spermidine; Spermine; Ureohydrolases | 2014 |
Microbacterium kyungheense sp. nov. and Microbacterium jejuense sp. nov., isolated from salty soil.
Topics: Actinomycetales; Bacterial Typing Techniques; Base Composition; DNA, Bacterial; Fatty Acids; Glycolipids; Molecular Sequence Data; Nucleic Acid Hybridization; Ornithine; Phylogeny; Republic of Korea; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil Microbiology; Spermidine; Vitamin K 2 | 2014 |
A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells.
Topics: Acetyltransferases; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cisplatin; Computational Biology; Drug Resistance, Neoplasm; Esophagus; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Metabolome; Models, Statistical; Neoplastic Stem Cells; Ornithine; Proteins; Putrescine; Spermidine; Spermine; Spermine Synthase; Transcriptome | 2016 |
Intracellular sources of ornithine for polyamine synthesis in endothelial cells.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Cyclohexanecarboxylic Acids; Endothelial Cells; Ornithine; Putrescine; Spermidine | 2016 |
Insights into the Biogenic Amine Metabolic Landscape during Industrial Semidry Chinese Rice Wine Fermentation.
Topics: Acids; Arginine; Biogenic Amines; Chromatography, High Pressure Liquid; Ethanol; Fermentation; Lactic Acid; Lactobacillus; Ornithine; Oryza; Putrescine; Spermidine; Spermine; Wine | 2016 |
Progesterone-associated arginine decline at luteal phase of menstrual cycle and associations with related amino acids and nuclear factor kB activation.
Topics: Adult; Amino Acids; Arginine; Citrulline; Female; Follicular Phase; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Luteal Phase; NF-kappa B p50 Subunit; Ornithine; Progesterone; Putrescine; Reference Values; Spermidine; Spermine; Transcription Factor RelA | 2018 |
Oral administration of l-ornithine increases the content of both collagen constituting amino acids and polyamines in mouse skin.
Topics: Administration, Oral; Amino Acids; Animals; Collagen; Male; Mice, Inbred ICR; Ornithine; Polyamines; Putrescine; Skin; Spermidine; Spermine | 2019 |
Understanding the influence of trenbolone acetate and polyamines on proliferation of bovine satellite cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cattle; Cell Proliferation; Dicarboxylic Acid Transporters; Gene Expression Regulation; Methionine; Mitochondrial Membrane Transport Proteins; Ornithine; Satellite Cells, Skeletal Muscle; Spermidine; Spermine; Trenbolone Acetate | 2021 |
Arginine Supplementation Promotes Extracellular Matrix and Metabolic Changes in Keratoconus.
Topics: Arginase; Arginine; Case-Control Studies; Cell Culture Techniques; Cells, Cultured; Collagen; Collagen Type I; Cornea; Extracellular Matrix; Fibroblasts; Humans; Keratoconus; Nitric Oxide Synthase; Ornithine; Spermidine; Up-Regulation | 2021 |
The importance of the urea cycle and its relationships to polyamine metabolism during ammonium stress in Medicago truncatula.
Topics: Amine Oxidase (Copper-Containing); Ammonium Compounds; Medicago truncatula; Ornithine; Polyamines; Putrescine; Spermidine; Urea | 2022 |
Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Firmicutes; Fructose; Gastrointestinal Microbiome; Glucans; Humans; Isoleucine; Leucine; Metabolome; Mice; Non-alcoholic Fatty Liver Disease; Ornithine; RNA, Ribosomal, 16S; Spermidine; Succinic Acid; Telmisartan; Tryptophan; Water | 2022 |
Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize.
Topics: Acetylation; Acetyltransferases; Animals; Catalysis; Humans; Lysine; Mammals; Ornithine; Polyamines; Spermidine; Spermine; Zea mays | 2023 |