ornithine has been researched along with putrescine in 388 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 274 (70.62) | 18.7374 |
| 1990's | 50 (12.89) | 18.2507 |
| 2000's | 24 (6.19) | 29.6817 |
| 2010's | 24 (6.19) | 24.3611 |
| 2020's | 16 (4.12) | 2.80 |
| Authors | Studies |
|---|---|
| Bey, P; Danzin, C; Jung, M; Mamont, P; Tardif, C; Van Dorsselaer, V | 1 |
| Harik, SI; Schwerin, F; Wehle, SU | 1 |
| Alexandre, H | 1 |
| Russell, DH; Stambrook, PJ | 1 |
| Linebaugh, BE; Mulder, JA; Rillema, JA | 1 |
| Alfant, M; Crandall, DE; Knott, CE; Tremblay, GS | 1 |
| Mamont, PS; McCann, PP; Tardif, C | 1 |
| Emanuelsson, H; Heby, O | 2 |
| Gigot, D; Penninckx, M | 1 |
| Morris, DR; Whitney, PA | 1 |
| Brawley, JV; Ferro, AJ | 1 |
| Stevens, L; Winther, MD | 1 |
| Pegg, AE | 1 |
| Bey, P; Danzin, C; Grove, J; Jung, MJ | 1 |
| Marton, LJ; Seidenfeld, J | 2 |
| Canellakis, ZN; Williams-Ashman, HG | 1 |
| Keir, HM; Melvin, MA; Wallace, HM | 1 |
| Hammond, JM; Veldhuis, JD | 1 |
| Alhonen-Hongisto, L; Jänne, J; Kallio, A; Pösö, H | 1 |
| Bacchi, CJ; Garofalo, J; Hutner, SH; Lipschik, GY; Vergara, C | 1 |
| McCormick, F | 1 |
| Brinkley, BR; Nishioka, K; Rao, PN; Sunkara, PS | 1 |
| Jänne, J; Koso, P; Piik, K; Pulkkinen, P | 1 |
| Bey, P; Duchesne, MC; Grove, J; Mamont, PS | 1 |
| Duchesne, MC; Grove, J; Mamont, PS; Tardif, C | 1 |
| Knutson, JC; Morris, DR | 1 |
| Guha, SK; Hölttä, E; Jänne, J | 1 |
| McKinnon, IM; Stevens, L; Winther, M | 1 |
| Stevens, L; Winther, M | 1 |
| Byus, CV; Herbst, EJ | 1 |
| Abdel-Monem, MM; Newton, NE | 1 |
| Jorstad, CM; Morris, DR; Seyfried, CE | 1 |
| Duffy, PE; Kremzner, LT | 1 |
| Asada, A; Gohda, E; Inoue, H; Mori, Y; Takeda, Y; Takigawa, M | 1 |
| Clark, JL | 1 |
| Gohda, E; Inoue, H; Kato, Y; Takeda, Y; Tamada, F | 1 |
| Bey, P; Böhlen, P; Mamont, PS; McCann, PP; Schuber, F; Tardif, C | 1 |
| Tait, GH | 1 |
| Bolin, RW; Cummings, DJ | 1 |
| Bachrach, U; Fischer, R; Klein, I | 1 |
| Adachi, K; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M | 1 |
| Abdel-Monem, MM; Newton, NE; Weeks, CE | 1 |
| Hiller, JM; Kremzner, LT; Simon, EJ | 1 |
| Ali, MR; Holaday, NJ; Jeevanandam, M | 1 |
| Dalla Via, L; Garlid, KD; Siliprandi, D; Toninello, A | 1 |
| Bowlin, TL; Flescher, E; Talal, N | 1 |
| Igarashi, K; Kashiwagi, K; Kobayashi, H; Miyamoto, S; Suzuki, F | 1 |
| Cler, JA; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Linebaugh, BE; Rillema, JA | 1 |
| Mates, JM; Medina, MA; Núñez de Castro, I; Sánchez-Jiménez, F; Urdiales, JL | 1 |
| Alunda, JM; Balaña-Fouce, R; Escribano, MI | 1 |
| Bear, HD; Lind, DS; Sekar, J; Susskind, BM; Tandon, PM | 1 |
| Byus, CV; Gonzalez, GG | 1 |
| Byus, CV; Wu, VS | 2 |
| Pegg, AE; Poulin, R; Wechter, RS | 1 |
| Kovacs, JA; Lipschik, GY; Masur, H | 1 |
| Baby, TG; Joseph, K | 1 |
| Blachier, F; Darcy-Vrillon, B; Duée, PH; Malaisse, WJ; Sener, A | 1 |
| Donatelli, MR; Schaeffer, JM | 1 |
| Dunzendorfer, U; Knöner, M | 1 |
| Bondy, SC; Emerich, D; Tilson, HA | 1 |
| Chen, KY; Cheng, S | 1 |
| Ascioti, C; Audino, MG; De Sarro, A; De Sarro, GB; Libri, V; Nisticò, G | 1 |
| Davis, RH; Ristow, JL | 1 |
| Eichler, W | 1 |
| Kadofuku, T; Sato, T; Shinki, T; Suda, T; Tanaka, H | 1 |
| Nambara, T; Oe, T; Shimada, K; Tanaka, M | 1 |
| Ekker, M; Sourkes, TL | 1 |
| Dascombe, MJ; Haegele, KD | 1 |
| Agnati, LF; Calza, L; Corti, A; Davalli, P; Fuxe, K; Goldstein, M; Piccinini, G; Toffano, G; Zini, I; Zoli, M | 1 |
| Erecińska, M; Pastuszko, A; Wilson, DF | 1 |
| Bondy, SC; Walker, CH | 1 |
| Chandrasekaran, J; Susskind, BM | 1 |
| Alhonen-Hongisto, L; Gahmberg, CG; Jänne, J; Jänne, OA; Kallio, A; Sinervirta, R | 1 |
| Blume, GB; Goldstone, AD; Koenig, H | 1 |
| Baylin, SB; Casero, RA; Luk, GD; Nelkin, BD | 1 |
| Clark, RS; McGovern, KA; Pegg, AE | 1 |
| Dorr, RT; Gerner, EW; Liddil, JD | 1 |
| Block, AL; Komar, KA; Naujokas, MF; Seidenfeld, J | 1 |
| Meilhoc, E; Moutin, MJ; Osborne, HB; Romani, BH | 1 |
| Bregman, MD; Meyskens, FL | 1 |
| Boyle, SM; Satishchandran, C | 2 |
| Dircks, L; Grens, A; Scheffler, IE; Slezynger, TC | 1 |
| Gerner, EW; Mamont, PS | 1 |
| Boldizsár, M; Holczinger, L; Kremmer, T | 1 |
| Seidenfeld, J; Williams-Ashman, HG | 1 |
| Inaba, M; Ishimura, E; Matsui-Yuasa, I; Morii, H; Morisada, S; Morisawa, S; Nishizawa, Y; Otani, S; Yukioka, K; Yukioka, M | 1 |
| Green, CD; Hoggard, N | 1 |
| Heby, O; Kanje, M; Mamont, PS; Oredsson, SM; Wagner, J | 1 |
| Chang, ZF; Chen, KY | 1 |
| Bacchi, CJ; Bitonti, AJ; Giffin, BF; McCann, PP | 1 |
| Bremner, AF; Coombs, GH; Lockwood, BC; North, MJ | 1 |
| Berger, FG; Porter, CW | 1 |
| Kadofuku, T; Sato, T; Shinki, T; Suda, T | 1 |
| Bacchi, CJ; Giffin, BF; McCann, PP | 1 |
| Gerner, EW; Glass, JR | 1 |
| Phillips, MA; Wang, CC | 1 |
| Reddy, SR; Subrahmanyam, TS | 1 |
| Hayakawa, C; Kato, T; Mizutani, N; Sano, M | 1 |
| Driessen, AJ; Konings, WN; Smid, EJ | 1 |
| Daune, G; Gerhart, F; Seiler, N | 1 |
| Igarashi, K; Kashiwagi, K | 1 |
| Dröge, W; Häcker-Shahin, B | 1 |
| Algranati, ID; Cataldi, AA | 1 |
| Hougaard, DM; Larsson, LI; Nielsen, JH | 1 |
| Weber, LW | 1 |
| Bitonti, AJ; Byers, TJ; Kim, BG; McCann, PP; Sobota, A | 1 |
| Halpern, YS; Metzer, E; Shaibe, E | 2 |
| Jetten, AM; Shirley, JE | 1 |
| Alhonen-Hongisto, L; Levin, VA; Marton, LJ | 1 |
| Homma, Y; Numata, I; Oyasu, R; Ozono, S; Seidenfeld, J | 1 |
| Kovach, JS; Svingen, PA | 1 |
| Herbst, EJ; Meeker, LD; Minocha, R; Ronan, AM; Thompson, HJ | 1 |
| Fujita, K; Hayashi, S; Kameji, T; Murakami, Y | 1 |
| Bacchi, CJ; Bitonti, AJ; McCann, PP; Sjoerdsma, A | 1 |
| Covey, DF; Fair, WR; Heston, WD; Uy, L | 1 |
| Pegg, AE; Shirahata, A | 1 |
| Königk, E; Putfarken, B | 1 |
| Deen, DF; Feuerstein, BG; Marton, LJ | 1 |
| Harvey, HA; Leitzel, KE; Lipton, A; Pegg, AE; Wolf, LM | 1 |
| Billgren, M; Heby, O; Oredsson, SM | 1 |
| Seidenfeld, J | 1 |
| Benrezzak, O; Morisset, J | 2 |
| Kahana, C; Nathans, D | 1 |
| Anehus, S; Heby, O; Linden, M; Oredsson, SM | 1 |
| Gurpide, E; Holinka, CF | 1 |
| Hahn, DA; Heston, WD; Kadmon, D; Mahle, C | 1 |
| Fuller, DJ; Gerner, EW; Glass, JR; Sertich, GJ | 1 |
| Hölttä, E; Jänne, OA; Pohjanpelto, P | 1 |
| Heby, O; Russell, DH | 2 |
| Brandt, JT; Fausto, N; Pierce, DA | 1 |
| Herbst, EJ; Lawler, D; Rothaus, K; Wyatt, GR | 1 |
| Hölttä, E; Jänne, J | 3 |
| Hannonen, P; Hölttä, E; Jänne, J; Pispa, J | 1 |
| Setlow, P | 1 |
| Feldman, MJ; Russell, DH | 1 |
| Coppoc, GL; Weber, G; Williams-Ashman, HG | 1 |
| Mainwaring, IP; Mangan, FR; Pegg, AE | 1 |
| Itin, A; Lazarus, LH | 1 |
| Harik, SI; Hollenberg, MD; Snyder, SH | 1 |
| Lembach, KJ | 1 |
| Kremzner, LT; Sturman, JA | 2 |
| Ottow, JC | 1 |
| Cohen, SS; Lapi, L; Massey, S; Rubenstein, KE; Streibel, E | 1 |
| Cohen, SS | 1 |
| Kleczkowski, K; Wielgat, B | 1 |
| Bell, CA; Munro, GF | 1 |
| Harik, SI; Pasternak, GW; Snyder, SH | 1 |
| Daubner, I; Tóth, D | 1 |
| Bode, VC; Harrison, DP | 1 |
| Celis, TF; Maas, WK; Rosenfeld, HJ | 1 |
| Russell, DH | 4 |
| Srinivasan, PR; Young, DV | 1 |
| Fillingame, RH; Morris, DR | 1 |
| Stalon, V | 1 |
| Tabor, CW; Tabor, H | 1 |
| McVicker, TA; Russell, DH | 1 |
| Domschke, S; Söling, HD | 1 |
| Inoue, H; Ono, M; Takeda, Y | 1 |
| Cantoni, GL; Schmidt, GL | 1 |
| Manen, CA; Russell, DH | 2 |
| Kay, JE; Lindsay, VJ | 1 |
| Grahn, B; Henningsson, SS; Kahlson, G; Rosengren, E | 1 |
| Ballesteros, LM; Hernandez, O; Mendez, D; Rosado, A | 1 |
| Mitchell, JL; Rusch, HP | 1 |
| Hölttä, E; Jänne, J; Sinervirta, R | 1 |
| Lambert, MA; Moss, CW | 1 |
| Ottow, JC; Zolg, W | 2 |
| Karrer, E; Warren, RA | 1 |
| Cottrell, GA; Gould, RM | 1 |
| Asada, A; Inoue, H; Kato, Y; Shiba, K; Tanioka, H | 1 |
| Jefferson, LS; Pegg, AE | 1 |
| Gaull, GE; Sturman, JA | 1 |
| Franks, NE | 1 |
| Cherry, WB; Lambert, MA; Moss, CW | 1 |
| Hannonen, P; Jänne, J; Raina, A | 1 |
| Aramaki, Y; Hayashi, S; Noguchi, T | 1 |
| Bellantone, RA; Canellakis, ES; Friedman, SJ | 1 |
| Kuttan, R; Radhakrishnan, AN | 1 |
| Inoue, H; Ono, M; Suzuki, F; Takeda, Y | 1 |
| Matsushita, S; Mueller, JF; Raben, MS; Sogani, RK | 1 |
| Icekson, I; Kaye, AM; Lindner, HR | 1 |
| Ishikawa, Y; Kaiser-Kupfer, MI; Kuwabara, T | 1 |
| Delcros, JG; Quash, G; Roch, AM | 1 |
| Inoue, H; Oka, T | 1 |
| Jänne, J; Käpyaho, K; Kousa, M; Lauharanta, J; Linnamaa, K; Mustakallio, K | 1 |
| Jänne, J; Käpyaho, K; Kariniemi, AL; Virtanen, I | 1 |
| Roth-Schechter, BF; Sarhan, S; Seiler, N | 1 |
| Bartolome, JV; Chait, EA; Slotkin, TA; Trepanier, PA | 1 |
| Baylin, SB; Collector, MI; Luk, GD; McCann, PP; Sensenbrenner, LL; Sharkis, SJ | 1 |
| Cramer, CL; Davis, RH; Paulus, TJ | 1 |
| Baylin, SB; Goodwin, G; Luk, GD; Marton, LJ | 1 |
| Hölttä, E; Hovi, T; Jänne, J; Vaheri, A; Vartio, T | 1 |
| Chambaz, EM; Duperray, A; Madani, C | 1 |
| Coffino, P; Marton, LJ; McConlogue, LC | 1 |
| Algranati, ID; Goldemberg, SH; Medrano, EE | 1 |
| Fields, A; Gibson, W; Irmiere, A; LaFemina, R; van Breemen, R | 1 |
| Fout, GS; Mapoles, JE; Medappa, KC; Rueckert, RR | 1 |
| Gillin, FD; McCann, PP; Reiner, DS | 1 |
| Kallio, A; Lyda, S; McCann, PP; Niskanen, EO; Pou, G; Thornhill, A | 1 |
| Chaney, JE; Digenis, GA; Goto, R; Kobayashi, K | 1 |
| Deen, DF; Hung, DT; Marton, LJ; Shafer, RH | 1 |
| Diekema, KA; Kingsnorth, AN; Malt, RA; McCann, PP; Russell, WE | 1 |
| Jänne, J; Käpyaho, K; Lauharanta, J | 1 |
| Abeloff, MD; Baylin, SB; Luk, GD; McCann, PP; Sharkis, SJ; Sjoerdsma, A | 1 |
| Kelly, M; McCann, PP; Schindler, J | 1 |
| Diaz-Flores, M; Durán, G; Hicks, JJ; Méndez, JD | 1 |
| Belleville, F; Brossat, B; Metz, R; Nabet, P; Straczek, J | 1 |
| Goldstone, AD; Koenig, H; Lu, CY | 1 |
| Covey, DF; Fair, WR; Heston, WD; Kadmon, D | 1 |
| Bethell, DR; Erwin, BG; Pegg, AE | 1 |
| Kufe, D; Shafman, T; Sugiura, M | 1 |
| Agam, G; Gartner, TK; Livne, A | 1 |
| Mamont, PS; Rudkin, BB; Seiler, N | 1 |
| Jänne, J; Kallio, A; Nikula, P | 1 |
| Griffin, J; Kufe, D; Mitchell, T; Shafman, T; Sugiura, M | 1 |
| Alhonen-Hongisto, L; Deen, DF; Marton, LJ | 1 |
| Canellakis, ES; Flamigni, F; Kyriakidis, DA; Pawlak, JW | 1 |
| Cavanaugh, PF; Pavelic, ZP; Porter, CW | 1 |
| Manni, A; Wright, C | 1 |
| Buckley, AR; Karrer, FM; Putnam, CW; Rhenman, B; Steinbronn, K; Warneke, JA | 1 |
| Heby, O; Kanje, M; Oredsson, SM | 1 |
| Iwashima, A; Oku, T; Yamanishi, K | 1 |
| Bartolome, J; Persons, D; Slotkin, TA; Whitmore, WL | 1 |
| Fong, WF; Ng, SF; Yao, KM | 1 |
| Black, O; Chang, BK; Gutman, R | 1 |
| Altiere, RJ; Gillespie, MN; Hacker, AD; Olson, JW | 1 |
| Anehus, S; Heby, O; Oredsson, SM | 1 |
| Davis, RH; Paulus, TJ | 2 |
| Daikuhara, Y; Gohda, E; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M | 1 |
| Bey, P; Danzin, C; Gerhart, F; Van Dorsselaer, V | 1 |
| Sarhan, S; Seiler, N | 1 |
| Haas, D; Mercenier, A; Simon, JP; Stalon, V | 1 |
| Anehus, S; Heby, O; Oredsson, S | 1 |
| Alhonen-Hongisto, L; Jänne, J | 1 |
| Kopple, JD; Swendseid, ME; Wang, M | 1 |
| Deen, DF; Marton, LJ; Seidenfeld, J | 1 |
| Gray, JW; Marton, LJ; Seidenfeld, J | 1 |
| Fozard, JR; Grove, J; Prakash, NJ | 1 |
| Seiler, N | 1 |
| Alhonen-Hongisto, L; Jänne, J; Seppänen, P | 2 |
| Deen, DF; Hung, DT; Marton, LJ; Seidenfeld, J | 1 |
| Fair, WR; Heston, WD; Lazan, DW | 1 |
| Bethell, DR; Pegg, AE | 1 |
| Persson, L | 2 |
| Pegg, AE; Pösö, H | 1 |
| Deen, DF; Marton, LJ; Oredsson, SM | 1 |
| Bethell, DR; Hibasami, H; Matsui, I; Pegg, AE | 1 |
| Erwin, BG; Florini, JR; Pegg, AE; Richman, RA; Stoscheck, CM | 1 |
| Jänne, J; Käpyaho, K; Linnamaa, K | 1 |
| Seppänen, P | 1 |
| Claverie, N; Danzin, C; Joder-Ohlenbusch, AM; Mamont, PS; Siat, M; Wagner, J | 1 |
| Boutwell, RK; Simsiman, RC; Takigawa, M; Verma, AK | 1 |
| Sunkara, PS; Verma, DS | 1 |
| Alhonen-Hongisto, L; Hölttä, E; Jänne, J; Seppänen, P | 1 |
| Barnes, GA; Bartolome, J; Lerea, L; Seidler, FJ; Slotkin, TA; Trepanier, PA; Weigel, SJ; Whitmore, WL | 1 |
| Deen, DF; Marton, LJ; Oredsson, SM; Tofilon, PJ | 1 |
| Fair, WR; Heston, WD; Kadmon, D; Lazan, DW | 1 |
| McCann, PP; Pegg, AE | 1 |
| Fuller, DJ; Gerner, EW | 1 |
| Bradford, MM; Chapman, WL; Hanson, WL; McCann, PP; Sjoerdsma, A; Waits, VB | 1 |
| Suzuki, F; Takano, T; Takigawa, M | 1 |
| Hölttä, E; Pohjanpelto, P | 1 |
| Sasaki, M | 1 |
| Hori, C; Oka, T; Perry, JW; Sakai, T | 1 |
| Kersten, H; Kersten, W; Mach, M | 1 |
| Henningsson, AC; Henningsson, S; Nilsson, M; Tjälve, H | 1 |
| Harada, JJ; Morris, DR; Porter, CW | 1 |
| Hamana, K; Matsuzaki, S; Suzuki, M | 1 |
| Forbes, WR; Yeager, RK | 1 |
| Aizencang, G; Frydman, B; Frydman, RB; Giorgieri, S; Guerra, L; Sambrotta, L | 1 |
| Higaki, I; Kinoshita, H; Matsui-Yuasa, I; Otani, S; Terakura, M | 1 |
| Blachier, F; Duée, PH; M'Rabet-Touil, H; Robert, V; Selamnia, M | 1 |
| Blachier, F; Cherbuy, C; Darcy-Vrillon, B; Duée, PH; Hellio, N; M'Rabet-Touil, H; Robert, V | 1 |
| Baydoun, AR; Morgan, DM | 1 |
| Bacchi, CJ; Yarlett, N | 1 |
| Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M; Peska, M | 1 |
| Bujidos, ML; Cubría, JC; Fouce, RB; Ordóñez, D; Reguera, RM | 1 |
| Hornsperger, JM; Knoedgen, B; Sablone, M; Sarhan, S; Seiler, N | 1 |
| Byus, CV; Fukumoto, GH; Hawel, L; Tjandrawinata, RR | 1 |
| Byus, CV; Hawel, L; Tjandrawinata, RR | 2 |
| Bogle, RG; Mann, GE; Morgan, DM; Pearson, JD | 1 |
| Alakuijala, L; Alhonen, L; Halmekytö, M; Halonen, T; Jänne, J; Kauppinen, R; MacDonald, E; Miettinen, R; Sinervirta, R; Sivenius, J | 1 |
| Bedoya, AM; Hernandez, SM; Isola, EL; Lammel, EM; Schwarcz de Tarlovsky, MN | 1 |
| Alakuijala, L; Alhonen, L; Halmekytö, M; Jänne, J | 1 |
| Smith, TK; Sousadias, MG | 1 |
| Coker, NJ; Henley, CM; Salzer, TA | 1 |
| Brooks, HB; Phillips, MA | 1 |
| Kahana, C; Tobias, KE | 1 |
| Floris, G; Lorrai, A; Medda, R; Padiglia, A; Pedersen, JZ | 1 |
| Laube, G; Veh, RW | 1 |
| Igarashi, K; Kashiwagi, K; Kuraishi, A; Shibuya, S; Tomitori, H | 1 |
| Byus, CV; Pastorian, KE | 1 |
| Czernichow, B; Galluser, M; Gossé, F; Nsi-Emvo, E; Raul, F | 1 |
| Calandra, RS; Frungieri, MB; González-Calvar, SI; Rulli, SB; Suescun, MO | 1 |
| Harada, JJ; Morris, DR | 1 |
| Cowley, T; McPherson, A; Walters, DR | 1 |
| Durante, W; Liao, L; Peyton, KJ; Schafer, AI | 2 |
| Andersen, SC; Bastola, DR; Minocha, SC | 1 |
| Tabib, A | 1 |
| Blachier, F; Duée, PH; Mayeur, C; Robert, V; Selamnia, M | 1 |
| Bauer, PM; Buga, GM; Fukuto, JM; Ignarro, LJ; Wei, LH | 1 |
| Arena, ME; Manca de Nadra, MC | 1 |
| Duranton, B; Gossé, F; Hasselmann, M; Raul, F; Schleiffer, R | 1 |
| Meurer-Grimes, B; Rovira, I; Walters, D | 1 |
| Baeza, I; Ibánez, M; Oró, J; Rodriguez-Paez, L; Santiago, JC; Wong, C | 1 |
| Galston, AW; Tiburcio, AF | 1 |
| Hawker, JR; Kelly, KA; Li, H; Meininger, CJ; Morris, SM; Wu, G | 1 |
| Bhatnagar, P; Minocha, R; Minocha, SC | 1 |
| Biol-N'Garagba, MC; George, P; Greco, S; Hugueny, I; Louisot, P | 1 |
| Alonso, C; Carcelén, J; Corraliza, I; Gómez-Nieto, LC; Iniesta, V; Mirón, C; Mohedano, A; Molano, I | 1 |
| McQuarrie, SA; Srinath, P; Suresh, MR | 1 |
| Andriamihaja, M; Blachier, F; Camous, S; Charpigny, G; Eklou-Kalonji, E; Mayeur, C; Reinaud, P; Robert, V | 1 |
| Mayer, MJ; Michael, AJ | 1 |
| Diegelman, P; Kee, K; Kisiel, N; Kramer, DL; Merali, S; Porter, CW; Powell, CT; Vujcic, S | 1 |
| DaMatta, RA; de Mello, FG; de Souza, W; Seabra, SH | 1 |
| Akella, R; Baldwin, J; Goldsmith, EJ; Jackson, LK; Phillips, MA | 1 |
| Bazer, FW; Hu, J; Johnson, GA; Spencer, TE; Wu, G | 1 |
| Balvay, S; Levillain, O; Peyrol, S | 1 |
| Goda, S; Kawarabayasi, Y; Ohshima, T; Sakuraba, H | 1 |
| Paneth, P; Sicinska, D; Truhlar, DG | 1 |
| Granchi, L; Guerrini, S; Mangani, S; Vincenzini, M | 1 |
| Cho, JY; Lee, YJ | 1 |
| Geller, DA; Ikeda, A; Jeyabalan, G; Kaizu, T; Murase, N; Reid, KM; Shao, L; Tsung, A; Wu, G | 1 |
| Cook, T; Feagin, JE; Keithly, JS; Morada, M; Roos, D; Wu, G; Yarlett, N; Zhu, G | 1 |
| Ando, A; Furuta, K; Igarashi, K; Ito, S; Kaneko, S; Maeda, M; Matsumura, M; Nishimura, K; Okuda-Ashitaka, E; Suzuki, M | 1 |
| Broadbent, JR; Christiansen, JK; Hughes, JE; Rodríguez, BT; Steele, JL; Welker, DL | 1 |
| Crespo, MT; Lolkema, JS; Pereira, CI; San Romão, MV | 1 |
| Long, S; Minocha, R; Minocha, SC; Mohapatra, S | 1 |
| Aoki, M; Denbow, DM; Furuse, M; Hamasu, K; Kabuki, Y; Kawada, Y; Kurauchi, I; Morishita, K; Shigemi, K; Yamane, H | 1 |
| Coton, E; Coton, M; Lolkema, JS; Mulder, N; Pochet, S; Trip, H | 1 |
| Elena-Herrmann, B; Emsley, L; Herrmann, T; Pontoizeau, C; Toulhoat, P | 1 |
| Guzmán-de-Peña, D; Ruiz-Herrera, J; Valdés-Santiago, L | 1 |
| Minocha, R; Minocha, SC; Page, AF | 1 |
| Lu, D; Peterson, LA; Phillips, MB; Sullivan, MM | 1 |
| Gandhi, S; Krishnan, UM; Rayappan, JB; Sethuraman, S; Shanmugam, S; Thandavan, K | 1 |
| Cantín, A; Gil-Ortiz, F; Polo, LM; Rubio, V | 1 |
| Gopinath, V; Lindner, SN; Meiswinkel, TM; Nampoothiri, KM; Wendisch, VF | 1 |
| Lolkema, JS; Lucas, PM; Romano, A; Trip, H | 1 |
| Long, S; Majumdar, R; Minocha, R; Minocha, SC; Shao, L | 1 |
| Aksnes, A; Andersen, SM; Espe, M; Holen, E; Rønnestad, I; Zerrahn, JE | 1 |
| Cynober, L; De Bandt, JP; Ramani, D | 1 |
| Bazer, FW; Burghardt, RC; Dunlap, KA; Lin, G; Satterfield, MC; Wang, X; Wu, G; Ying, W | 1 |
| Kumar, R; Rafia, S; Saran, S | 1 |
| Doki, Y; Ishii, H; Kano, Y; Kawamoto, K; Konno, M; Koseki, J; Matsui, H; Mori, M; Nishida, N | 1 |
| Bazer, FW; Li, H; Meininger, CJ; Wu, G | 1 |
| Wang, W; Xia, X; Zhang, B; Zhang, Q; Zhang, W | 1 |
| Cordts, K; Gribbon, P; Hennig, A; Nau, WM; Nilam, M; Reinshagen, J; Schwedhelm, E | 1 |
| Feng, LS; Jiang, XL; Li, Z; Liu, JZ; Shen, YP | 1 |
| Alvarez, MA; Alvarez-Sieiro, P; Del Rio, B; Fernandez, M; Ladero, V; Martin, MC; Redruello, B | 1 |
| Faustmann, G; Gruber, HJ; Magnes, C; Meinitzer, A; Obermayer-Pietsch, B; Ribalta, J; Rock, E; Roob, JM; Tiran, B; Winklhofer-Roob, BM | 1 |
| Aso, K; Furuse, M; Harada, D; Ikeda, K; Nagamachi, S; Takahashi, Y | 1 |
| Bai, F; Chen, M; Lan, X; Li, S; Liao, Z; Wang, J; Yang, C; Zhao, T; Zhou, Q | 1 |
| Cai, F; Chen, F; DeBerardinis, RJ; Gao, X; Ge, WP; He, F; Lin, H; Liu, W; Luo, B; Sun, W; Vu, HS; Xing, C; Xiong, N; Xu, H; Yao, DX; Yuan, Y; Zacharias, LG; Zhang, FC; Zhao, H | 1 |
| Chai, X; He, M; Li, B; Liu, S; Ma, H; Pan, J; Wang, J; Wang, Y; Zhan, J | 1 |
| Bao, X; Fu, L; Wang, F; Wang, Y; Yang, R; Zhang, Y | 1 |
| Chen, Q; Liu, S; Liu, X; Ma, H; Wang, J | 1 |
| Lafleur, N; Lavergne, CLJ; Liu, XJ; Ren, Y; Tao, Y | 1 |
| Ansari, Z; Barvkar, VT; Nadaf, AB; Renuka, N; Wang, C; Zhang, Y; Zhao, C | 1 |
| Chi, Z; Chi, ZM; Kong, CC; Liu, GL; Wei, X | 1 |
| Buezo, J; Cerdán, D; Cornejo, A; Esteban, R; Gogorcena, Y; López-Gómez, P; Martínez-Merino, V; Moran, JF; Royo, B; Tavladoraki, P; Urra, M | 1 |
| Groll, J; Keller, T; Koepsell, H | 1 |
| Baier, T; Einhaus, A; Freudenberg, RA; Kruse, O; Wittemeier, L | 1 |
| Alghamdi, SA; Amano, A; Fukusaki, E; Kuboniwa, M; Lamont, RJ; Mayumi, S; Sakanaka, A; Shimma, S | 1 |
| Liang, M; Qiao, X; Song, H; Song, R; Song, Z; Zhang, Q | 1 |
| Nguyen Hoang, KN; Phillips, RS | 1 |
| Avila-Pacheco, J; Bando, JK; Cao, S; Cleveland, JL; Clish, C; Colonna, M; Peng, V; Trsan, T; Xavier, RJ | 1 |
| Ami, Y; Kodama, N; Koyanagi, T; Kurihara, S; Nakamura, H; Shirasawa, H; Umeda, M | 1 |
12 review(s) available for ornithine and putrescine
| Article | Year |
|---|---|
Spermine, spermidine and putrescine in fungal development.
Topics: Arginine; Fungi; Methionine; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Spores, Fungal | 1979 |
Polyamines in mammalian liver during growth and development.
Topics: Animals; Chick Embryo; Hormones; Humans; Liver; Liver Neoplasms; Liver Regeneration; Mammals; Ornithine; Pharmacology; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1976 |
Aspects of the biochemical pharmacology of methyl glyoxal bis(guanylhydrazone).
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Carnitine; Cell Division; DNA Replication; Eflornithine; Energy Metabolism; Humans; Kinetics; Leukemia; Male; Mitochondria; Mitoguazone; Nucleic Acids; Ornithine; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Polyamines; Protein Biosynthesis; Putrescine; Virus Replication | 1986 |
Some roles of polyamines in microbial physiology.
Topics: Binding Sites; DNA; Escherichia coli; Haemophilus; Mutation; Ornithine; Polyamines; Potassium; Putrescine; RNA; RNA, Bacterial; Saccharomyces cerevisiae; Sodium; Spermidine; Time Factors | 1972 |
The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues.
Topics: Animals; Carboxy-Lyases; DNA-Directed RNA Polymerases; Drug Synergism; Humans; Neoplasms; Ornithine; Polyamines; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Spermine; Xenopus | 1973 |
Regulation of amino acid decarboxylation.
Topics: Amino Acids; Animals; Arginine; Biogenic Amines; Carboxy-Lyases; Diamines; Enzyme Activation; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lysine; Organ Specificity; Ornithine; Pimelic Acids; Putrescine; S-Adenosylmethionine; Spermidine; Spermine | 1974 |
Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines.
Topics: Acylation; Amidines; Amine Oxidase (Copper-Containing); Animals; Arginine; Bacteria; Carboxy-Lyases; Escherichia coli; Fungi; Ornithine; Plants; Polyamines; Propylamines; Putrescine; Rats; RNA; Spermidine; Spermine; Transferases; Ureohydrolases; Viruses | 1972 |
On the role of GABA in vertebrate polyamine metabolism.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Kinetics; Liver; Mice; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Trout | 1980 |
Polyamine metabolism and function.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Division; Eflornithine; Humans; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine | 1982 |
Parasite polyamine metabolism: targets for chemotherapy.
Topics: Animals; Antiporters; Bacterial Proteins; Biological Transport; Eflornithine; Escherichia coli Proteins; Female; Humans; Ornithine; Polyamines; Putrescine; Trichomonas vaginalis; Trichomonas Vaginitis | 1994 |
Polyamines in the male reproductive system.
Topics: Acetyltransferases; Animals; Biogenic Polyamines; Cricetinae; Epididymis; Humans; Male; Mammals; Mesocricetus; Mice; Ornithine; Prostate; Putrescine; Rats; Semen; Seminal Vesicles; Spermidine; Spermine; Testis | 1996 |
Aliphatic polyamines in physiology and diseases.
Topics: Agmatine; Animals; Disease Models, Animal; Humans; Neoplasms; Ornithine; Putrescine; Spermidine; Spermine | 2014 |
376 other study(ies) available for ornithine and putrescine
| Article | Year |
|---|---|
Analogues of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site.
Topics: Animals; Binding Sites; Carboxy-Lyases; Cattle; In Vitro Techniques; Liver; Male; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prostate; Rats; Structure-Activity Relationship | 1978 |
Axonal transport of polyamines: a reappraisal.
Topics: Animals; Axonal Transport; Male; Ornithine; Polyamines; Putrescine; Rats; Sciatic Nerve; Spermidine; Spinal Cord | 1979 |
[Effect of inhibitors of polyamine biosynthesis on primary differentiation of mouse egg].
Topics: Animals; Cell Differentiation; Cells, Cultured; Female; Fertilization; Guanidines; Mice; Mitoguazone; Ornithine; Ovum; Putrescine | 1978 |
Cell cycle specific fluctuations in adenosine 3':5'-cyclic monophosphate and polyamines of Chinese hamster cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Line; Cricetinae; Cyclic AMP; Ornithine; Ornithine Decarboxylase; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Time Factors | 1975 |
Regulation of casein synthesis by polyamines in mammary gland explants of mice.
Topics: Animals; Arginine; Caseins; Cyclic AMP; Cyclic GMP; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Phospholipases; Polyamines; Prolactin; Prostaglandins F; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic | 1977 |
Orotic acid biosynthesis in rat liver: studies on the source of carbamoylphosphate.
Topics: Ammonia; Ammonium Chloride; Animals; Bicarbonates; Carbamates; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Carbon Radioisotopes; Glutamine; Liver; Mitochondria, Liver; Ornithine; Orotic Acid; Phosphotransferases; Putrescine; Rats | 1977 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Liver Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Inhibition of putrescine synthesis blocks development of the polychete Ophryotrocha labronica at gastrulation.
Topics: Animals; Embryo, Nonmammalian; Female; Mitoguazone; Ornithine; Polychaeta; Putrescine; Spermine; Time Factors; Zygote | 1978 |
Synthesis and interaction with Escherichia coli L-ornithine carbamolytransferase of two potential transition-state analogues.
Topics: Escherichia coli; Kinetics; Ornithine; Ornithine Carbamoyltransferase; Phosphonoacetic Acid; Putrescine; Structure-Activity Relationship | 1978 |
Polyamine auxotrophs of Saccharomyces cerevisiae.
Topics: Adenosylmethionine Decarboxylase; Genes; Genetic Complementation Test; Genetic Linkage; Ornithine; Ornithine Decarboxylase; Putrescine; Saccharomyces cerevisiae; Spermidine; Spermine | 1978 |
Polyamine biosynthesis during germination of yeast ascospores.
Topics: Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Saccharomyces cerevisiae; Spores, Fungal | 1979 |
Ornithine as a possible marker of cancer.
Topics: Animals; Neoplasms, Experimental; Ornithine; Putrescine; Rats | 1979 |
Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues.
Topics: Animals; Carboxy-Lyases; Male; Organ Size; Organ Specificity; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Putrescine; Rats; Spermidine; Spermine; Testis; Thymus Gland | 1979 |
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Depression, Chemical; Dose-Response Relationship, Drug; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1979 |
Polyamines in mammalian biology and medicine.
Topics: Adenosylmethionine Decarboxylase; Animals; Isoelectric Point; Molecular Conformation; Neoplasms; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; Semen; Sexual Maturation; Spermidine; Spermine; Structure-Activity Relationship | 1979 |
Decreased excretion of polyamines from BHK-21/C13 cells treated with alpha-methylornithine [proceedings].
Topics: Animals; Cell Line; Cricetinae; Kidney; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1979 |
Role of ornithine decarboxylase in granulosa-cell replication and steroidogenesis in vitro.
Topics: Animals; Carboxy-Lyases; Cell Division; Cells, Cultured; Female; Granulosa Cells; Kinetics; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prolactin; Putrescine; Sheep; Steroids | 1979 |
Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Diamines; DNA, Neoplasm; Female; Guanidines; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Time Factors | 1979 |
Synthesis and content of polyamines in bloodstream Trypanosma brucei.
Topics: Amino Acids; Animals; Arginine; Blood; Methionine; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Spermine; Trypanosoma brucei brucei | 1979 |
Polyamine metabolism in enucleated mouse L-cells.
Topics: Animals; Cell Nucleus; L Cells; Mice; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine | 1977 |
Possible involvement of putrescine in nucleolar formation in early embryos.
Topics: Animals; Cell Nucleolus; Female; Ornithine; Ovum; Polychaeta; Putrescine | 1978 |
Role of polyamines in cytokinesis of mammalian cells.
Topics: Cell Division; Cell Line; Cytoskeleton; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1979 |
Effect of polyamines and their oxidized derivatives on the metabolism of rat epididymal spermatozoa.
Topics: Adenosine Triphosphate; Animals; Cadaverine; Calcium; Epididymis; Fructose; Glucose; Histamine; Male; Ornithine; Putrescine; Rats; Spermatozoa; Spermidine; Spermine | 1978 |
Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase.
Topics: Carboxy-Lyases; Cell Division; Cell Line; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1978 |
Initial characterization of a HTC cell variant partially resistant to the anti-proliferative effect of ornithine decarboxylase inhibitors.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cell Division; Cell Line; Cell Membrane Permeability; Clone Cells; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1978 |
Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei.
Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Replication; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine | 1978 |
Polyamine and ornithine metabolism during the germination of conidia of Aspergillus nidulans.
Topics: Adenosylmethionine Decarboxylase; Aspergillus nidulans; Cycloheximide; DNA; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ornithine-Oxo-Acid Transaminase; Polyamines; Putrescine; Spores, Fungal; Time Factors | 1976 |
Synthesis of polyamines in the germinating conidia of Aspergillus nidulans.
Topics: Aspergillus nidulans; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Spores, Fungal | 1976 |
Decarboxylases for polyamine biosynthesis in Drosophila melanogaster larvae.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drosophila melanogaster; Kinetics; Larva; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; S-Adenosylmethionine | 1976 |
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).
Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; DNA Replication; Drug Interactions; Guanidines; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mitoguazone; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine | 1977 |
Ornithine decarboxylase activity and polyamines in relation to aging of human fibroblasts.
Topics: Carboxy-Lyases; Cell Division; Cell Line; Cell Survival; Guanidines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
The role of putrescine in cell proliferation of the skin of mice induced by ethylphenylpropriolate.
Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cell Division; Diamines; DNA; Epidermal Cells; Male; Ornithine; Ornithine Decarboxylase; Propionates; Putrescine; Skin; Spermidine; Spermine | 1977 |
Ornithine decarboxylase assay using ion-exchange paper.
Topics: Carbon Dioxide; Carboxy-Lyases; Cell Line; Chromatography, Ion Exchange; Chromatography, Paper; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine | 1976 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism and growth of mouse sarcoma-180.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cell Division; Depression, Chemical; DNA, Neoplasm; Hydrazines; Liver; Male; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; RNA, Neoplasm; Sarcoma 180; Spermidine; Spermine; Valine | 1976 |
Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.
Topics: Cell Division; Cells, Cultured; DNA Replication; Kinetics; Leucine; Ornithine; Putrescine; Spermidine; Spermine | 1976 |
A new pathway for the biosynthesis of spermidine.
Topics: Anaerobiosis; Arginine; Aspartic Acid; Fumarates; Light; Methionine; Ornithine; Paracoccus denitrificans; Putrescine; Rhodobacter sphaeroides; Spermidine | 1976 |
Canavanine-mediated depletion of polyamine pools in Escherichia coli: effect of head morphogenesis and DNA synthesis.
Topics: Arginine; Canavanine; Coliphages; DNA Viruses; DNA, Viral; Escherichia coli; Micropore Filters; Morphogenesis; Ornithine; Polyamines; Putrescine; Spermidine; Stereoisomerism; Thymine; Tritium; Virus Replication | 1975 |
Occurrence of polyamines in coliphages T5, phiX174 and in phage-infected bacteria.
Topics: Carboxy-Lyases; Coliphages; Dansyl Compounds; DNA Viruses; DNA, Bacterial; DNA, Viral; Escherichia coli; Ornithine; Phosphates; Polyamines; Putrescine; Spermidine | 1975 |
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism in isoproterenol-stimulated mouse parotid glands.
Topics: Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Carboxy-Lyases; DNA; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Mice; Mitoguazone; Mitosis; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Parotid Gland; Polyamines; Putrescine; RNA; Spermidine; Spermine; Stimulation, Chemical; Valine | 1975 |
Inhibitors of polyamine biosynthesis. 3. (+/-)-5-Amino-2-hydrazine-2-methylpentanoic acid, an inhibitor of ornithine decarboxylase.
Topics: Animals; Carboxy-Lyases; Cattle; Concanavalin A; Decarboxylation; Hydrazines; In Vitro Techniques; Kinetics; Lymphocyte Activation; Lymphocytes; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Putrescine; Pyridoxal Phosphate; Rats | 1975 |
Metabolism of polyamines in mouse neuroblastoma cells in culture: formation of GABA and putreanine.
Topics: Aminobutyrates; Cell Line; gamma-Aminobutyric Acid; Neuroblastoma; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1975 |
Altered tissue polyamine levels due to ornithine-alpha-ketoglutarate in traumatized growing rats.
Topics: Acetylation; Animals; Femur; Food, Fortified; Intestines; Liver; Male; Muscles; Ornithine; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine | 1992 |
Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter.
Topics: Animals; Biological Transport; Hydrogen-Ion Concentration; Kinetics; Lysine; Membrane Potentials; Mitochondria, Liver; Ornithine; Putrescine; Rats; Spermidine; Spermine; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Thermodynamics | 1992 |
Regulation of IL-2 production by mononuclear cells from rheumatoid arthritis synovial fluids.
Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Female; Humans; Interleukin-2; Male; Middle Aged; Monocytes; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Prostaglandin Antagonists; Putrescine; Synovial Fluid | 1992 |
Excretion of putrescine by the putrescine-ornithine antiporter encoded by the potE gene of Escherichia coli.
Topics: Antiporters; Bacterial Proteins; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Kinetics; Molecular Sequence Data; Ornithine; Plasmids; Putrescine; Transformation, Bacterial | 1992 |
Polyamines modulate events mediated by the N-methyl-D-aspartate (NMDA) receptor complex through an ifenprodil-insensitive pathway: in vivo measurements of cyclic GMP in the cerebellum.
Topics: Animals; Biogenic Polyamines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Injections, Intraventricular; Male; Methamphetamine; Mice; Neural Pathways; Ornithine; Pentylenetetrazole; Piperidines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine | 1991 |
Polyamine influences on the prolactin stimulation of phosphoprotein synthesis in hydroxyurea synchronized MCF-7 human mammary epithelial cells.
Topics: Cell Cycle; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Female; G1 Phase; Humans; Hydroxyurea; Insulin; Interphase; Leucine; Ornithine; Phosphoproteins; Polyamines; Prolactin; Protein Processing, Post-Translational; Putrescine; S Phase; Spermidine; Tritium | 1991 |
Diamines interfere with the transport of L-ornithine in Ehrlich-cell plasma-membrane vesicles.
Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Membrane; Diamines; Glutamine; Histamine; Humans; Ornithine; Putrescine; Serotonin | 1991 |
Leishmania infantum: polyamine biosynthesis and levels during the growth of promastigotes.
Topics: Animals; Decarboxylation; Diminazene; Dogs; Eflornithine; Leishmania donovani; Methionine; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Trypanocidal Agents | 1991 |
Differential sensitivity of cytotoxic T lymphocytes and lymphokine-activated killer cells to inhibition by L-ornithine.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Arginine; CD8 Antigens; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Immunity, Cellular; Interleukin-2; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Mice; Mice, Inbred Strains; Ornithine; Putrescine; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic | 1991 |
Effect of dietary arginine restriction upon ornithine and polyamine metabolism during two-stage epidermal carcinogenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arginine; DNA; Female; Mice; Ornithine; Ornithine Decarboxylase; Papilloma; Polyamines; Putrescine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
The level of substrate ornithine can alter polyamine-dependent DNA synthesis following phorbolester stimulation of cultured hepatoma cells.
Topics: Animals; Arginine; Blood; Clone Cells; Culture Media; DNA; Eflornithine; Insulin; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
An early enlargement of the putrescine pool is required for growth in L1210 mouse leukemia cells under hypoosmotic stress.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Enzyme Induction; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Osmolar Concentration; Polyamines; Putrescine; Tumor Cells, Cultured | 1991 |
Polyamine metabolism in Pneumocystis carinii.
Topics: Animals; Arginine; Eflornithine; Lung; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pentamidine; Pneumocystis; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1991 |
Early developmental profile of ornithine decarboxylase in the frog, Microhyla ornata and its regulation by polyamines.
Topics: Animals; Embryo, Nonmammalian; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Ranidae; Spermidine | 1991 |
Arginine metabolism in rat enterocytes.
Topics: Animals; Arginine; Citrulline; Female; Intestinal Mucosa; Ornithine; Oxidation-Reduction; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Urea | 1991 |
Characterization of a high-affinity membrane-associated ornithine decarboxylase from the free-living nematode Caenorhabditis elegans.
Topics: Amino Acids; Animals; Arginine; Caenorhabditis; Cell Compartmentation; Cell Membrane; Kinetics; Nematoda; Nucleotides; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Solubility; Species Specificity; Subcellular Fractions | 1990 |
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Carcinoma; Eflornithine; Estrogens; Humans; Male; Mitoguazone; Neoplasm Metastasis; Ornithine; Ornithine Decarboxylase Inhibitors; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Putrescine; Rats; Spermidine; Spermine | 1985 |
Inhibition of ornithine decarboxylase alters neurological responsiveness to a tremorigen.
Topics: Animals; Behavior, Animal; Chlordecone; Eflornithine; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Inbred F344; Tremor | 1986 |
Polyamine metabolism in an obligately alkalophilic Bacillus alcalophilus that grows at pH 11.0.
Topics: Arginine; Bacillus; Biological Transport, Active; Chromatography, High Pressure Liquid; Escherichia coli; Gramicidin; Hydrogen-Ion Concentration; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Sodium; Spermidine; Spermine; Valinomycin | 1988 |
Behavioural and electrocortical effects after injection of two ornithine decarboxylase inhibitors into several areas of the brain in the rat.
Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Cerebral Cortex; Eflornithine; Electroencephalography; Hippocampus; Injections; Injections, Intraventricular; Male; Muscimol; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Thalamus | 1989 |
Uptake, intracellular binding, and excretion of polyamines during growth of Neurospora crassa.
Topics: Arginase; Arginine; Biological Transport; Cell Membrane; Cell Membrane Permeability; Mutation; Neurospora; Neurospora crassa; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermidine Synthase | 1989 |
Inhibition of L-arginine iminohydrolase (EC 3.5.3.6) from Tetrahymena thermophila by putrescine and spermidine: feedback control of polyamine biosynthesis.
Topics: Animals; Arginine; Feedback; Hydrolases; Ornithine; Putrescine; Spermidine; Tetrahymena | 1989 |
Major pathway for putrescine synthesis induced by 1 alpha,25-dihydroxyvitamin D3 in chick duodenum.
Topics: Acetyltransferases; Animals; Calcitriol; Chickens; Duodenum; In Vitro Techniques; Male; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine | 1989 |
Sensitive ferrocene reagents for derivatization of amines for high-performance liquid chromatography with electrochemical detection.
Topics: Amines; Chromatography, High Pressure Liquid; Electrochemistry; Ferrous Compounds; Indicators and Reagents; Metallocenes; Organometallic Compounds; Ornithine; Ornithine Decarboxylase; Putrescine | 1989 |
Effects of alpha-difluoromethylornithine on polyamine biosynthesis and tyrosine hydroxylase induction in the adrenal gland of the rat subjected to stress or apomorphine.
Topics: Adrenal Glands; Animals; Apomorphine; Cold Temperature; Eflornithine; Enzyme Induction; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Restraint, Physical; Spermidine; Spermine; Stress, Physiological; Tyrosine 3-Monooxygenase | 1985 |
Evidence against putrescine and polyamines as endogenous mediators of fever.
Topics: Animals; Eflornithine; Endotoxins; Fever; Ornithine; Polyamines; Putrescine; Rabbits; Shigella dysenteriae; Spermidine; Spermine | 1985 |
Effects of lesions and ganglioside GM1 treatment on striatal polyamine levels and nigral DA neurons. A role of putrescine in the neurotropic activity of gangliosides.
Topics: Animals; Corpus Striatum; Dopamine; Eflornithine; G(M1) Ganglioside; Male; Neurons; Ornithine; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Substantia Nigra; Tyrosine 3-Monooxygenase | 1985 |
A role for transglutaminase in neurotransmitter release by rat brain synaptosomes.
Topics: Animals; Brain; Cadaverine; Catecholamines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eflornithine; gamma-Aminobutyric Acid; Male; Methylamines; Neurotransmitter Agents; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Synaptosomes; Transglutaminases | 1986 |
Polyamines contribute to calcium-stimulated release of aspartate from brain particulate fractions.
Topics: Animals; Aspartic Acid; Calcium; Dopamine; Eflornithine; Frontal Lobe; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Ornithine; Ornithine Decarboxylase; Polyamines; Potassium; Putrescine; Rats; Synaptosomes | 1986 |
Inhibition of cytolytic T lymphocyte maturation with ornithine, arginine, and putrescine.
Topics: Amine Oxidase (Copper-Containing); Animals; Antigen-Presenting Cells; Arginine; Cattle; Cell Differentiation; Cells, Cultured; Culture Media; Cytotoxicity, Immunologic; Depression, Chemical; Lymphocyte Culture Test, Mixed; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine; Phytohemagglutinins; Putrescine; T-Lymphocytes, Cytotoxic | 1987 |
Tumourigenicity, cell-surface glycoprotein changes and ornithine decarboxylase gene pattern in Ehrlich ascites-carcinoma cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; DNA, Neoplasm; Eflornithine; Electrophoresis, Polyacrylamide Gel; Gene Amplification; Glycoproteins; Membrane Proteins; Mice; Ornithine; Ornithine Decarboxylase; Phenotype; Putrescine | 1985 |
Association of increased polyamine levels with isoproterenol-stimulated mucin secretion in the rat submandibular gland.
Topics: Animals; Eflornithine; Glucosamine; Isoproterenol; L-Lactate Dehydrogenase; Male; Mucins; Ornithine; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Submandibular Gland; Time Factors | 1985 |
Human lung tumor sensitivity to difluoromethylornithine as related to ornithine decarboxylase messenger RNA levels.
Topics: Carcinoma; Carcinoma, Small Cell; Cell Cycle; Cells, Cultured; Eflornithine; Humans; Lung Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; RNA, Messenger | 1986 |
Effect of 1,3,6-triaminohexane and 1,4,7-triaminoheptane on growth and polyamine metabolism in SV-3T3 cells treated with 2-difluoromethylornithine.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Viral; Eflornithine; Fibroblasts; Heptanes; Hexanes; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Simian virus 40; Spermidine | 1986 |
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines.
Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Eflornithine; Etoposide; Humans; Leukemia L1210; Mice; Multiple Myeloma; Nucleic Acid Conformation; Ornithine; Podophyllotoxin; Polyamines; Putrescine | 1986 |
Altered cell cycle phase distributions in cultured human carcinoma cells partially depleted of polyamines by treatment with difluoromethylornithine.
Topics: Cell Cycle; Cell Line; DNA; Dose-Response Relationship, Drug; Eflornithine; Flow Cytometry; Humans; Ornithine; Polyamines; Putrescine | 1986 |
Relationship between ornithine decarboxylase activity and hexamethylene bisacetamide-induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Clone Cells; Dexamethasone; Eflornithine; Erythrocytes; Interphase; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1986 |
Difluoromethylornithine enhances inhibition of melanoma cell growth in soft agar by dexamethasone, clone A interferon and retinoic acid.
Topics: Cell Line; Cell Survival; Dexamethasone; Drug Combinations; Drug Synergism; Eflornithine; Humans; Interferon Type I; Melanoma; Ornithine; Putrescine; Tretinoin | 1986 |
Purification and properties of agmatine ureohydrolyase, a putrescine biosynthetic enzyme in Escherichia coli.
Topics: Agmatine; Arginine; Edetic Acid; Egtazic Acid; Escherichia coli; Hydrogen-Ion Concentration; Isoelectric Point; Kinetics; Metals; Molecular Weight; Nucleotides; Ornithine; Polyamines; Putrescine; Temperature; Ureohydrolases | 1986 |
Posttranscriptional regulation of ornithine decarboxylase activity.
Topics: Animals; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Eflornithine; Emetine; Female; Half-Life; Ornithine; Ornithine Decarboxylase; Ovary; Protein Processing, Post-Translational; Putrescine; RNA, Messenger | 1986 |
Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.
Topics: Alkynes; Animals; Cell Division; Cells, Cultured; Diamines; Eflornithine; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1986 |
In vivo effects of DL-alpha-difluoromethylornithine on the polyamine and nucleotide phosphate metabolism in P388/S leukemia cells.
Topics: Animals; Cell Line; Eflornithine; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Nucleotides; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Time Factors | 1986 |
Polyamines in 1 alpha, 25-dihydroxycholecalciferol-induced differentiation of human promyelocytic leukemia cells, HL-60.
Topics: Acetyltransferases; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Eflornithine; Humans; Leukemia, Myeloid; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
Polyamines and growth regulation of cultured human breast cancer cells by 17 beta-oestradiol.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Humans; Insulin; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Tamoxifen | 1986 |
Polyamine depletion increases cellular ribonucleotide levels.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Chromatography, High Pressure Liquid; Eflornithine; Mice; Ornithine; Putrescine; Rats; S-Adenosylmethionine; Spermine | 1986 |
Age dependency of the metabolic conversion of polyamines into amino acids in IMR-90 human embryonic lung diploid fibroblasts.
Topics: Amino Acids; Cell Line; Cell Survival; Diploidy; Eflornithine; Enzyme Induction; Fibroblasts; Humans; Lysine; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Processing, Post-Translational; Putrescine | 1986 |
Polyamine depletion following exposure to DL-alpha-difluoromethylornithine both in vivo and in vitro initiates morphological alterations and mitochondrial activation in a monomorphic strain of Trypanosoma brucei brucei.
Topics: Animals; Dihydrolipoamide Dehydrogenase; Eflornithine; Male; Mitochondria; Ornithine; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Trypanosoma brucei brucei | 1986 |
Polyamine biosynthesis in trichomonads.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Culture Media; Eflornithine; Eukaryota; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Trichomonas vaginalis; Tritrichomonas | 1986 |
Putrescine does not mediate the androgen-response in mouse kidney.
Topics: Animals; Eflornithine; Female; Kidney; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; RNA, Messenger; Spermidine; Spermine; Testosterone | 1986 |
Spermidine N1-acetyltransferase has a larger role than ornithine decarboxylase in 1 alpha,25-dihydroxyvitamin D3-induced putrescine synthesis.
Topics: Acetyltransferases; Animals; Calcitriol; Chickens; Duodenum; Eflornithine; Epithelium; Intestinal Mucosa; Kinetics; Male; Ornithine; Ornithine Decarboxylase; Putrescine; Vitamin D Deficiency | 1986 |
Effect of putrescine on the respiration of Trypanosoma brucei brucei.
Topics: Animals; Eflornithine; Magnesium; Male; Mitochondria; Ornithine; Oxygen Consumption; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Trypanosoma brucei brucei | 1986 |
Polyamine-mediated turnover of ornithine decarboxylase in Chinese-hamster ovary cells.
Topics: Animals; Cells, Cultured; Chemical Precipitation; Cricetinae; Cricetulus; Eflornithine; Female; Immunoelectrophoresis; Ornithine; Ornithine Decarboxylase; Ovary; Peptide Fragments; Putrescine; Spermidine | 1986 |
A Trypanosoma brucei mutant resistant to alpha-difluoromethylornithine.
Topics: Animals; Arginine; Drug Resistance; Eflornithine; Mutation; Ornithine; Ornithine Decarboxylase; Putrescine; Trypanosoma brucei brucei | 1987 |
L-ornithine and L-lysine need their alpha-carboxyl groups for effective inhibition of bovine liver arginase.
Topics: Animals; Arginase; Cadaverine; Cattle; Diamines; Kinetics; Liver; Lysine; Ornithine; Putrescine; Structure-Activity Relationship | 1986 |
Increased urinary excretion of putrescine in hyperargininaemia.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Arginine; Child; Child, Preschool; Citrulline; Cystinuria; Humans; Male; Ornithine; Putrescine | 1987 |
Transport of diamines by Enterococcus faecalis is mediated by an agmatine-putrescine antiporter.
Topics: Agmatine; Antiporters; Bacterial Proteins; Biological Transport; Carrier Proteins; Citrulline; Diamines; Enterococcus faecalis; Guanidines; Hydrolases; Ornithine; Putrescine | 1988 |
5-Fluoromethylornithine, an irreversible and specific inhibitor of L-ornithine:2-oxo-acid aminotransferase.
Topics: Animals; Brain; Female; In Vitro Techniques; Liver; Male; Mice; Ornithine; Ornithine-Oxo-Acid Transaminase; Putrescine; Rats; Rats, Inbred Strains; Time Factors; Transaminases | 1988 |
Adjustment of polyamine contents in Escherichia coli.
Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Escherichia coli; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine | 1988 |
Putrescine and its biosynthetic precursor L-ornithine augment the in vivo immunization against minor histocompatibility antigens and syngeneic tumor cells.
Topics: Animals; Cytotoxicity, Immunologic; Histocompatibility Antigens; Immunization; Interleukin-2; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ornithine; Putrescine; Spleen | 1986 |
A probable new pathway for the biosynthesis of putrescine in Escherichia coli.
Topics: Arginine; Carboxy-Lyases; Chromatography, Thin Layer; Escherichia coli; Glucose; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Ureohydrolases | 1986 |
Localization and biosynthesis of polyamines in insulin-producing cells.
Topics: Animals; Cells, Cultured; Glucose; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Mice; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1986 |
A practicable variant of the ion exchange method for the radiometric estimation of ornithine decarboxylase activity.
Topics: Animals; Brain; Chromatography, Ion Exchange; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine; Pyridoxal Phosphate; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tritium | 1987 |
Polyamine metabolism in Acanthamoeba: polyamine content and synthesis of ornithine, putrescine, and diaminopropane.
Topics: Acanthamoeba; Animals; Arginase; Arginine; Citrulline; Diamines; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1987 |
Metabolic pathway for the utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12.
Topics: Agmatine; Arginine; Escherichia coli; Genotype; Guanidines; Kinetics; Mutation; Nitrogen; Ornithine; Putrescine; Species Specificity | 1985 |
Control of utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12.
Topics: Agmatine; Ammonia; Arginine; Escherichia coli; Genes; Genes, Bacterial; Genotype; Glucose; Glutamine; Guanidines; Nitrogen; Ornithine; Phenotype; Putrescine; Species Specificity; Succinates | 1985 |
Inhibition of ornithine decarboxylase by retinoic acid and difluoromethylornithine in relation to their effects on differentiation and proliferation.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Eflornithine; Fibroblasts; Kinetics; Mice; Mice, Inbred BALB C; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Teratoma; Tretinoin | 1985 |
Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Eflornithine; Guanidines; Kinetics; Mitochondria; Mitoguazone; Ornithine; Putrescine; Pyruvates; Pyruvic Acid; Rats; Spermidine; Temperature; Time Factors | 1985 |
Inhibition of carcinogenesis by alpha-difluoromethylornithine in heterotopically transplanted rat urinary bladders.
Topics: Animals; Eflornithine; Male; Methylnitrosourea; Ornithine; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
Enhancement of the antiproliferative activity of human interferon by polyamine depletion.
Topics: Aspirin; Cell Division; Cell Line; Doxorubicin; Drug Synergism; Eflornithine; Humans; Indomethacin; Interferon Type I; Neoplasms; Ornithine; Polyamines; Putrescine; Tumor Stem Cell Assay | 1985 |
Effect of concentration of D,L-2-difluoromethylornithine on murine mammary carcinogenesis.
Topics: Animals; Antineoplastic Agents; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Putrescine; Rats; Rats, Inbred Strains | 1985 |
Accumulation of ornithine decarboxylase-antizyme complex in HMOA cells.
Topics: Animals; Cells, Cultured; Chemical Precipitation; Chromatography, Gel; Cycloheximide; Eflornithine; Liver Neoplasms, Experimental; Methods; Ornithine; Ornithine Decarboxylase Inhibitors; Proteins; Putrescine; Rats | 1985 |
Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis.
Topics: Animals; Eflornithine; Kinetics; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |
Cytotoxic activity of aziridinyl putrescine enhanced by polyamine depletion with alpha-difluoromethylornithine.
Topics: Antineoplastic Agents; Cell Line; Eflornithine; Humans; Male; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine | 1985 |
Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cycloheximide; Eflornithine; Half-Life; Immunosorbent Techniques; Kinetics; Liver; Male; Mitoguazone; Molecular Weight; Ornithine; Prostate; Putrescine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1985 |
Ornithine decarboxylase of Plasmodium falciparum: a peak-function enzyme and its inhibition by chloroquine.
Topics: Animals; Chloroquine; Drug Interactions; Eflornithine; Hydrogen-Ion Concentration; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plasmodium falciparum; Putrescine; Spermidine | 1985 |
Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Survival; Cyclohexylamines; Eflornithine; Mitoguazone; Ornithine; Polyamines; Putrescine; Rats; Spermidine Synthase; Transferases | 1985 |
The in vitro interaction of alpha-difluoromethyl ornithine (DFMO) and several interferons on human cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Drug Interactions; Eflornithine; Female; Humans; Interferon Type I; Interferon-gamma; Melanoma; Ornithine; Putrescine | 1985 |
Induction of F9 embryonal carcinoma cell differentiation by inhibition of polyamine synthesis.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Thin Layer; Eflornithine; Embryonal Carcinoma Stem Cells; Mice; Neoplastic Stem Cells; Ornithine; Ornithine Decarboxylase; Plasminogen Activators; Polyamines; Putrescine; Teratoma; Tretinoin | 1985 |
Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells.
Topics: Cell Division; Cell Line; Clone Cells; Eflornithine; Female; Humans; Kinetics; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1985 |
Reversal of alpha-difluoromethylornithine inhibition of caerulein-induced pancreatic growth by putrescine.
Topics: Animals; Body Weight; Ceruletide; DNA; DNA Replication; Eflornithine; Male; Organ Size; Ornithine; Ornithine Decarboxylase Inhibitors; Pancreas; Putrescine; Rats; Rats, Inbred Strains | 1985 |
Translational regulation of mammalian ornithine decarboxylase by polyamines.
Topics: Animals; Cell Line; Drug Resistance; Eflornithine; Mice; Multiple Myeloma; Ornithine; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Putrescine; RNA, Messenger | 1985 |
Inhibition of ornithine decarboxylase activity and cell growth by diamines: a comparison between the effects of two homologs, 1,3-diaminopropane and 1,4-diaminobutane (putrescine).
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Diamines; Eflornithine; Flow Cytometry; Kinetics; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine | 1985 |
Ornithine decarboxylase activity in human endometrium and endometrial cancer cells.
Topics: Adenocarcinoma; Cell Division; Cell Line; Corpus Luteum; Cycloheximide; Dactinomycin; Eflornithine; Endometrium; Female; Follicular Phase; Humans; Molybdenum; Ornithine; Ornithine Decarboxylase; Progesterone; Putrescine; Time Factors; Uterine Neoplasms | 1985 |
Effect of estrogen and androgen administration on alpha-difluoromethylornithine-enhanced putrescine uptake by the rat prostate.
Topics: Animals; Diethylstilbestrol; Dihydrotestosterone; Eflornithine; Male; Ornithine; Polyamines; Prostate; Putrescine; Rats; Rats, Inbred Strains | 1985 |
Altered polyamine metabolism in Chinese hamster cells growing in a defined medium.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood; Cell Count; Cell Division; Cell Line; Cricetinae; Culture Media; Female; Ornithine; Ornithine Decarboxylase; Ovary; Polyamines; Putrescine; Spermidine; Spermine | 1986 |
Mutant strain of Chinese hamster ovary cells with no detectable ornithine decarboxylase activity.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Culture Media; Female; Fibroblasts; Ornithine; Ornithine Decarboxylase; Ovary; Polyamines; Putrescine; RNA, Messenger | 1985 |
Depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carboxy-Lyases; Cytidine; Depression, Chemical; Enzyme Repression; Injections, Intraperitoneal; Leukemia L1210; Liver; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Organ Size; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spleen; Triazines | 1973 |
Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy.
Topics: Animals; Carboxy-Lyases; Dactinomycin; Depression, Chemical; Electrophoresis, Paper; Hydrocortisone; Hypertrophy; In Vitro Techniques; Kidney; Kidney Diseases; Nephrectomy; Ornithine; Putrescine; Rats; Spermidine; Spermine; Stimulation, Chemical | 1972 |
Ornithine decarboxylase and polyamines in silkmoth pupal tissues: effects of ecdysone and injury.
Topics: Adipose Tissue; Animals; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Dactinomycin; Ecdysone; Female; Insecta; Male; Ornithine; Pupa; Putrescine; Spermidine; Spermine; Time Factors; Wings, Animal | 1973 |
Regulation of ornithine decarboxylase activity by putrescine and spermidine in rat liver.
Topics: Animals; Carboxy-Lyases; Cycloheximide; Female; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Ornithine; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Time Factors; Tyrosine Transaminase | 1974 |
Putrescine metabolizing enzyme activities in some rat tissues during postnatal development.
Topics: Age Factors; Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Female; Intestine, Small; Liver; Ornithine; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spleen; Thymus Gland; Time Factors; Transferases | 1973 |
Effect of methylglyoxal bis(guanylhydrazone) on polyamine metabolism in normal and regenerating rat liver and rat thymus.
Topics: Aldehydes; Amidines; Amine Oxidase (Copper-Containing); Animals; Carbon Radioisotopes; Carboxy-Lyases; Female; Glyoxal; Hydrazones; Kinetics; Lethal Dose 50; Liver; Liver Regeneration; Ornithine; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Thymus Gland | 1973 |
Spermidine biosynthesis during germination and subsequent vegetative growth of Bacillus megaterium spores.
Topics: Arginine; Bacillus megaterium; Canavanine; Carbon Radioisotopes; Carboxy-Lyases; Depression, Chemical; Ornithine; Putrescine; Spermidine; Spermine; Spores, Bacterial; Time Factors; Tritium | 1974 |
Polyamine biogenesis in left ventricle of the rat heart after aortic constriction.
Topics: Animals; Aorta; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cardiomegaly; Constriction; Decarboxylation; Female; Heart Ventricles; Male; Myocardium; Organ Size; Ornithine; Polyamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Stress, Mechanical | 1972 |
Imbalance in ornithine metabolism in hepatomas of different growth rates as expressed in formation of putrescine, spermidine, and spermine.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Electrophoresis, Paper; Liver; Liver Neoplasms; Male; Neoplasm Transplantation; Neoplasms, Experimental; Ornithine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Transplantation, Homologous | 1972 |
A reappraisal of the effects of adenosine 3':5'-cyclic monophosphate on the function and morphology of the rat prostate gland.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Carboxy-Lyases; Castration; Cyclic AMP; Cyproterone; Dihydrotestosterone; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Glucosephosphate Dehydrogenase; Male; Ornithine; Prostate; Protein Binding; Putrescine; Rats; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Subcellular Fractions; Testosterone; Time Factors; Tritium | 1973 |
Activity of foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s.
Topics: Aphthovirus; Arginine; Cadaverine; DNA; DNA-Directed RNA Polymerases; Heparin; Hydrogen-Ion Concentration; Kinetics; Lysine; Ornithine; Peptides; Polyamines; Putrescine; RNA, Viral; Spectrophotometry, Ultraviolet; Spermine; Time Factors | 1973 |
Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Depression, Chemical; DNA; Hepatectomy; Hydrazines; Liver; Liver Neoplasms; Liver Regeneration; Ornithine; Putrescine; Rats; RNA; Tritium; Uridine | 1974 |
Regulation of growth in vitro. I. Control of ornithine decarboxylase levels in untransformed and transformed mouse fibroblasts by serum.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Culture Techniques; Fibroblasts; Kinetics; Mice; Ornithine; Putrescine; Simian virus 40; Spermidine; Spermine; Time Factors; Trypsin | 1974 |
Polyamine biosynthesis and vitamin B6 deficiency. Evidence for pyridoxal phosphate as coenzyme for S-adenosylmethionine decarboxylase.
Topics: Animals; Arginine; Brain; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme Activation; Liver; Male; Organ Specificity; Ornithine; Polyamines; Putrescine; Pyridoxal Phosphate; Rats; S-Adenosylmethionine; Spermidine; Spermine; Ultracentrifugation; Vitamin B 6 Deficiency | 1974 |
Arginine dihydrolase activity in species of the genus Bacillus revealed by thin-layer chromatography.
Topics: Arginine; Bacillus; Chromatography, Thin Layer; Citrulline; Hydrolases; Hydrolysis; Ornithine; Putrescine; Species Specificity | 1974 |
Polyamine metabolism in potassium-deficient bacteria.
Topics: Arginine; Bacterial Proteins; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Culture Media; Escherichia coli; Methionine; Mutation; Ornithine; Potassium; Putrescine; RNA, Bacterial; S-Adenosylmethionine; Sodium; Spermidine; Urea | 1972 |
Comparative studies on ornithine carbamoyltransferase.
Topics: Animals; Cattle; Citrulline; Electrophoresis; Hydrogen-Ion Concentration; Liver; Ornithine; Ornithine Carbamoyltransferase; Plants; Putrescine; Salmonella typhimurium | 1973 |
Polyamine requirements of a conditional polyamine auxotroph of Escherichia coli.
Topics: Arginine; Cadaverine; Canavanine; Carbohydrate Metabolism; Carbon Isotopes; Culture Media; Densitometry; Escherichia coli; Glucose; Mutation; Ornithine; Osmolar Concentration; Polyamines; Putrescine; Spermidine; Spermine; Urease | 1973 |
An enzymatic-isotopic microassay for putrescine.
Topics: Animals; Biogenic Amines; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme Activation; Heart; Kidney; Liver; Liver Regeneration; Male; Methods; Mice; Microchemistry; Ornithine; Prostate; Putrescine; Rats; S-Adenosylmethionine; Saccharomyces cerevisiae; Spleen; Testis; Tritium | 1973 |
[Quantitative measurement of the decarboxylating activity of E. coli].
Topics: Aminobutyrates; Arginine; Cadaverine; Carboxy-Lyases; Colorimetry; Decarboxylation; Densitometry; Electrophoresis, Paper; Escherichia coli; Feces; Glutamates; Guanidines; Humans; Lysine; Methods; Ornithine; Putrescine | 1973 |
Distinct effects of diamines, polyamines, and magnesium ions on the stability of lambda phage heads.
Topics: Cadaverine; Calcium; Coliphages; DNA, Viral; Drug Stability; Escherichia coli; Lysine; Magnesium; Mutation; Nucleic Acid Conformation; Ornithine; Polyamines; Propylamines; Putrescine; Spermidine; Spermine; Thymidine; Tritium; Viral Proteins | 1973 |
Mutant of Escherichia coli K-12 defective in the transport of basic amino acids.
Topics: Arginine; Biological Transport; Carbon Radioisotopes; Chromosome Mapping; Chromosomes, Bacterial; Culture Media; Enzyme Repression; Escherichia coli; Genetic Linkage; Histidine; Lysine; Mutation; Ornithine; Putrescine; Time Factors; Tritium | 1973 |
Growth of ribonucleic acid bacteriophage f2 in a conditional putrescine auxotroph of Escherichia coli: evidence for a polyamine role in translation.
Topics: Arginine; Carbon Radioisotopes; Cell-Free System; Coliphages; Culture Media; DNA-Directed RNA Polymerases; Escherichia coli; Leucine; Mutation; Ornithine; Protein Biosynthesis; Putrescine; Rifampin; RNA, Messenger; RNA, Viral; Spermidine; Tritium; Uracil; Viral Proteins | 1974 |
Regulation of the catabolic ornithine carbamoyltransferase of Pseudomonas fluorescens. A study of the allosteric interactions.
Topics: Allosteric Regulation; Carbamates; Citrulline; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Organophosphorus Compounds; Ornithine; Ornithine Carbamoyltransferase; Phosphates; Protein Conformation; Pseudomonas; Pseudomonas fluorescens; Putrescine | 1972 |
Polyamine biogenesis in the rat mammary gland during pregnancy and lactation.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Epithelial Cells; Epithelium; Female; Lactation; Mammary Glands, Animal; Ornithine; Polyamines; Pregnancy; Pregnancy, Animal; Putrescine; Rats; Ribonucleases; RNA; Spermidine; Spermine | 1972 |
Polyamine metabolism in rat liver: effect of starvation and refeeding.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; DNA; Liver; Male; Ornithine; Polyamines; Proteins; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Spermine; Starvation; Time Factors | 1973 |
Effect of thioamide derivatives on induction of ornithine decarboxylase in rat liver.
Topics: Acetamides; Adrenal Glands; Adrenalectomy; Amides; Animals; Carboxy-Lyases; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Induction; Growth Hormone; Hypophysectomy; Liver; Male; Ornithine; Pituitary Gland; Putrescine; Rats; Spermidine; Spermine; Thiourea; Time Factors | 1973 |
Adenosylmethionine decarboxylase in developing rat brain.
Topics: Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Cell Nucleus; Cytosol; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Male; Mitochondria; Myelin Sheath; Ornithine; Osmolar Concentration; Putrescine; Pyridoxal Phosphate; Rats; S-Adenosylmethionine; Synaptosomes | 1973 |
Spermine is major polyamine in sea urchins: studies of polyamines and their synthesis in developing sea urchins.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Paper; Electrophoresis; Methionine; Ornithine; Putrescine; Sea Urchins; Spermidine; Spermine | 1973 |
Control of ornithine decarboxylase activity in stimulated human lymphocytes by putrescine and spermidine.
Topics: Blood Proteins; Carbon Isotopes; Carboxy-Lyases; Cells, Cultured; Cycloheximide; DNA; Humans; Lectins; Lymphocytes; Ornithine; Phenylalanine; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Alterations in the activities of ornithine and histidine decarboxylases provoked by testosterone in mice.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Histidine; Indicators and Reagents; Kidney; Liver; Mice; Nitrobenzenes; Ornithine; Putrescine; Testosterone; Time Factors | 1973 |
Polyamine synthesis and polysome patterns in the rat uterus during the oestrous cycle.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, Thin Layer; Estrus; Female; Nucleoproteins; Ornithine; Polyamines; Polyribosomes; Pregnancy; Putrescine; Rats; Spermidine; Spermine; Ultracentrifugation; Uterus | 1973 |
Regulation of polyamine synthesis in Physarum polyciphalum during growth and differentiation.
Topics: Carbon Isotopes; Carboxy-Lyases; Cell Differentiation; Culture Media; Cycloheximide; Electrophoresis, Paper; Mitosis; Myxomycetes; Ornithine; Polyamines; Protein Denaturation; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Subcellular Fractions; Time Factors | 1973 |
Synthesis and accumulation of polyamines in rat liver regenerating after treatment with carbon tetrachloride.
Topics: Animals; Carbon Radioisotopes; Carbon Tetrachloride; Carboxy-Lyases; Chromatography, Ion Exchange; Chromatography, Paper; Female; Growth Hormone; Hepatectomy; Liver; Liver Regeneration; Ornithine; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Thioacetamide; Time Factors; Transferases | 1973 |
Use of gas chromatography for detecting ornithine and lysine decarboxylase activity in bacteria.
Topics: Cadaverine; Carboxy-Lyases; Chromatography, Gas; Culture Media; Enterobacteriaceae; Lysine; Ornithine; Pseudomonas; Putrescine; Salmonella; Vibrio cholerae | 1973 |
Improved thin-layer technique for detection of arginine dihydrolase among the Pseudomonas species.
Topics: Arginine; Carboxy-Lyases; Chromatography, Thin Layer; Citrulline; Guanidines; Hydrolases; Methods; Micropore Filters; Ornithine; Pseudomonas; Putrescine; Solvents; Species Specificity | 1973 |
Effects of methylglyoxal-bis(guanylhydrazone) on polyamine metabolism in spleens of mice with disseminated L1210 lymphoid leukemia.
Topics: Amidines; Animals; Antineoplastic Agents; Carboxy-Lyases; Glyoxal; Hydrazones; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Spleen; Time Factors | 1974 |
Regulation of ornithine decarboxylase synthesis. Effect of a nutritional deficiency of vitamin B6.
Topics: Animals; Apoproteins; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dithiothreitol; Liver; Male; Organ Specificity; Ornithine; Putrescine; Pyridoxal Phosphate; Pyridoxine; Rats; Spermidine; Vitamin B 6 Deficiency | 1974 |
Precursors of polyamines in Pseudomonas acidovorans.
Topics: Arginine; Carbon Radioisotopes; Chromatography; Glutamates; Micropore Filters; Ornithine; Polyamines; Pseudomonas; Putrescine; Spermidine | 1974 |
Putrescine in molluscs: identification and occurrence in neurones and other tissues.
Topics: Animals; Autoanalysis; Chromatography, Gel; Chromatography, Thin Layer; Dansyl Compounds; Fresh Water; Isoleucine; Kidney; Leucine; Mass Spectrometry; Mollusca; Myocardium; Neurons; Organ Specificity; Ornithine; Putrescine; Seawater; Snails; Species Specificity | 1974 |
Effect of isoproterenol on polyamine metabolism in mouse salivary glands.
Topics: Animals; Carbon Radioisotopes; Carboxy-Lyases; Cycloheximide; DNA; Enzyme Induction; Isoproterenol; Male; Methionine; Mice; Organ Size; Ornithine; Parotid Gland; Pilocarpine; Polyamines; Putrescine; RNA; Salivary Glands; Spermidine; Spermine; Stimulation, Chemical; Submandibular Gland; Time Factors; Uridine | 1974 |
Effect of methylglyoxal bis(guanylhydrazone) on S-adenosylmethionine decarboxylase in the isolated perfused rat.
Topics: Aldehydes; Animals; Carboxy-Lyases; Cattle; Electrophoresis; Enzyme Activation; Erythrocytes; Glyoxal; Guanidines; Half-Life; Hematocrit; Hydrazones; Liver; Male; Nitriles; Ornithine; Perfusion; Putrescine; Rats; S-Adenosylmethionine; Time Factors; Tritium | 1974 |
Thin-layer chromatography of arginine, lysine and ornithine decarboxylase activity among Pseudomonas spp. and Enterobacteriaceae.
Topics: Arginine; Cadaverine; Carboxy-Lyases; Chromatography, Thin Layer; Enterobacteriaceae; Guanidines; Lysine; Methods; Ornithine; Pseudomonas; Putrescine; Species Specificity | 1974 |
Polyamine biosynthesis in human fetal liver and brain.
Topics: Adult; Age Factors; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Female; Fetus; Humans; Liver; Ornithine; Polyamines; Pregnancy; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine | 1974 |
Catabolism of L-arginine by entrapped cells of Streptococcus faecalis ATCC8043.
Topics: Acrylamides; Arginine; Citrulline; Enterococcus faecalis; Gels; Hydrogen-Ion Concentration; Kinetics; Methods; Microscopy, Electron; Muramidase; Ornithine; Polymers; Putrescine | 1971 |
Use of gas chromatography for determining catabolic products of arginine by bacteria.
Topics: Arginase; Arginine; Bacteria; Canavanine; Carboxy-Lyases; Chromatography, Gas; Citrulline; Hydrolases; Ornithine; Polyamines; Putrescine; Species Specificity; Stereoisomerism | 1972 |
Polyamine synthesis in the regenerating rat liver: stimulation of S-adenosyl methionine decarboxylase, and spermidine and spermine synthases after partial hepatectomy.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Half-Life; Hepatectomy; Kinetics; Liver; Liver Regeneration; Ornithine; Polyamines; Propylamines; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Spermine; Transferases | 1972 |
Diurnal change in ornithine decarboxylase activity of rat liver.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Carboxy-Lyases; Caseins; Circadian Rhythm; Dietary Proteins; DNA; Drug Synergism; Enzyme Induction; Growth Hormone; Hypophysectomy; Liver; Male; Ornithine; Prednisolone; Putrescine; Rats; Starvation | 1972 |
Ornithine decarboxylase activity in synchronously growing Don C cells.
Topics: Animals; Anti-Bacterial Agents; Benzocycloheptenes; Carbon Isotopes; Carboxy-Lyases; Cell Line; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; DNA; Leucine; Lung; Ornithine; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine; Thymidine; Tritium; Uridine | 1972 |
Studies on the biosynthesis of sym-homospermidine in sandal (Santalum album L.).
Topics: Aldehydes; Amidines; Arginine; Autoradiography; Carbon Isotopes; Chromatography, Paper; Glutamates; Ornithine; Oxidation-Reduction; Plants; Polyamines; Putrescine; Spermidine | 1972 |
Studies on ornithine decarboxylase from the liver of thioacetamide-treated rats. Purification and some properties.
Topics: Acetamides; Aminobutyrates; Animals; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Disc; Enzyme Activation; Isoelectric Focusing; Isoniazid; Keto Acids; Liver; Liver Regeneration; Male; Molecular Weight; Ornithine; Putrescine; Rats; Subcellular Fractions; Sulfhydryl Compounds; Sulfides | 1972 |
Stimulation of ornithine decarboxylase activity in rat tissues by growth hormone and by serum growth factor from rats infested with spargana of Spirometra mansonoides.
Topics: Adipose Tissue; Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cestoda; Dithiothreitol; Enzyme Activation; Female; Growth Hormone; Growth Substances; Hydrogen-Ion Concentration; Hypophysectomy; Kidney; Liver; Lung; Muscles; Myocardium; Ornithine; Pituitary Gland; Putrescine; Rats; Sparganosis; Spleen; Thymus Gland | 1972 |
Effects of methotrexate and cytosine arabinoside on polyamine metabolism in a mouse L1210 leukemia.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cytarabine; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Spleen | 1972 |
Ornithine decarboxylase activity and the accumulation of putrescine at early stages of liver regeneration.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cytosol; Female; Liver; Liver Regeneration; Ornithine; Proteins; Putrescine; Rats; S-Adenosylmethionine; Spermidine; Time Factors | 1972 |
Drug stimulation of putrescine and spermidine syntheses. Relationships to enhancement of ribonucleic acid synthesis.
Topics: Animals; Benzopyrenes; Carboxy-Lyases; Clofibrate; Cycloheximide; Heparin; Liver; Male; Methylcholanthrene; Ornithine; Phenobarbital; Polyamines; Putrescine; Rats; RNA; S-Adenosylmethionine; Spermidine; Stimulation, Chemical; Tritium; Uridine | 1971 |
Stimulation by estrogens of ornithine and S-adenosylmethionine decarboxylases in the immature rat uterus.
Topics: Animals; Benzopyrans; Carbon Isotopes; Carboxy-Lyases; Cycloheximide; Diethylstilbestrol; Enzyme Activation; Estradiol; Estrogens; Estrus; Female; Flavonoids; Kinetics; Liver; Methionine; Organ Specificity; Ornithine; Pregnancy; Puromycin; Putrescine; Rats; S-Adenosylmethionine; Testosterone; Tritium; Uridine; Uterus | 1971 |
Toxic effects of ornithine and its related compounds on the retina.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Lysine; Ornithine; Pigment Epithelium of Eye; Proline; Putrescine; Rats; Rats, Inbred Strains; Retina | 1982 |
The competitive inhibition of tissue transglutaminase by alpha-difluoromethylornithine.
Topics: Acyltransferases; Animals; Caseins; Eflornithine; Guinea Pigs; Kinetics; Liver; Ornithine; Putrescine; Transglutaminases | 1984 |
The effect of inhibitors of ornithine decarboxylase on DNA synthesis in mouse mammary gland in culture. The importance of osmolarity of the medium and of the initial intracellular level of putrescine.
Topics: Animals; Carboxy-Lyases; Culture Media; DNA; DNA Replication; Female; Insulin; Kinetics; Mammary Glands, Animal; Mice; Organ Culture Techniques; Ornithine; Ornithine Decarboxylase Inhibitors; Osmolar Concentration; Pregnancy; Protein Biosynthesis; Putrescine; RNA | 1980 |
Methylglyoxal BIS (guanylhydrazone) and alpha-difluoromethylornithine-induced polyamine deprivation in psoriatic lesions.
Topics: Carboxy-Lyases; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Humans; Injections, Intradermal; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1982 |
Effect of polyamine antimetabolites on cultured human keratinocytes from normal and uninvolved psoriatic skin.
Topics: Antimetabolites; Cell Division; Cells, Cultured; DNA; Eflornithine; Guanidines; Humans; Keratins; Mitoguazone; Ornithine; Protein Biosynthesis; Psoriasis; Putrescine; Skin; Spermidine; Spermine | 1984 |
Polyamines and the development of isolated neurons in cell culture.
Topics: Alkynes; Animals; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Chick Embryo; Diamines; Eflornithine; Nerve Tissue Proteins; Neurons; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; RNA | 1984 |
Role of polyamines in isoproterenol-induced cardiac hypertrophy: effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase.
Topics: Animals; Cardiomegaly; Eflornithine; Isoproterenol; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains | 1982 |
Regulation of hematopoiesis II: the role of polyamine inhibition on helper or suppressor influences of the thymus.
Topics: Animals; Bone Marrow Cells; Colony-Forming Units Assay; Eflornithine; Erythrocytes; Hematopoiesis; Male; Mice; Ornithine; Polyamines; Putrescine; Spleen; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thymus Gland | 1983 |
Compartmentation of spermidine in Neurospora crassa.
Topics: Carbon Radioisotopes; Kinetics; Neurospora; Neurospora crassa; Ornithine; Putrescine; Spermidine; Spermine; Subcellular Fractions | 1983 |
Polyamines are necessary for the survival of human small-cell lung carcinoma in culture.
Topics: Carcinoma, Small Cell; Cell Aggregation; Cell Division; Cell Survival; Cells, Cultured; Eflornithine; Humans; Lung Neoplasms; Ornithine; Polyamines; Putrescine | 1981 |
Temperature-dependent and transformation-associated changes in polyamine metabolism in normal and Rous sarcoma virus-infected chick embryo fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Eflornithine; Fibroblasts; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine; Temperature | 1981 |
Role of polyamines in the proliferation and steroidogenic activities of bovine adrenocortical cells in culture.
Topics: Adrenal Cortex; Animals; Carboxy-Lyases; Cattle; Cell Division; Cells, Cultured; Cosyntropin; Cyclic AMP; Eflornithine; Hydrocortisone; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1981 |
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells.
Topics: Adenosylmethionine Decarboxylase; Animals; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Eflornithine; Interphase; Lymphoma; Mice; Models, Biological; Ornithine; Ornithine Decarboxylase; Polyamines; Protein Kinases; Putrescine; Spermidine | 1983 |
Differential effect of alpha-difluoromethyl-ornithine on the proliferation of Balb 3T3 and chemically transformed 3T3 cells.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Eflornithine; Interphase; Kinetics; Mice; Mice, Inbred BALB C; Ornithine; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; Putrescine; Transcription, Genetic | 1983 |
Antagonistic transcriptional regulation of the putrescine biosynthetic enzyme agmatine ureohydrolase by cyclic AMP and agmatine in Escherichia coli.
Topics: Agmatine; Arginine; Chloramphenicol; Cyclic AMP; Enzyme Induction; Escherichia coli; Guanidines; Kinetics; Ornithine; Putrescine; Transcription, Genetic; Ureohydrolases | 1984 |
D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication.
Topics: Cells, Cultured; Cytomegalovirus; DNA, Viral; Eflornithine; Humans; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Simplexvirus; Spermidine; Spermine; Viral Proteins; Virion; Virus Replication | 1984 |
Radiochemical determination of polyamines in poliovirus and human rhinovirus 14.
Topics: Eflornithine; HeLa Cells; Humans; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Poliovirus; Putrescine; Rhinovirus; Spermidine; Spermine | 1984 |
Inhibition of growth of Giardia lamblia by difluoromethylornithine, a specific inhibitor of polyamine biosynthesis.
Topics: Animals; Eflornithine; Entamoeba histolytica; Giardia; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Trichomonas vaginalis | 1984 |
Microinjection of purified ornithine decarboxylase into Xenopus oocytes selectively stimulates ribosomal RNA synthesis.
Topics: Animals; Carboxy-Lyases; Eflornithine; Female; Guanosine; Microinjections; Oocytes; Ornithine; Ornithine Decarboxylase; Ovum; Putrescine; RNA, Ribosomal; Xenopus laevis | 1983 |
Divergent effects of ornithine decarboxylase inhibition on murine erythropoietic precursor cell proliferation and differentiation.
Topics: Animals; Bone Marrow; Carboxy-Lyases; Cell Differentiation; Cell Division; Cells, Cultured; Eflornithine; Hematopoietic Stem Cells; Kinetics; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine | 1983 |
Tumor selective enhancement of radioactivity uptake in mice treated with alpha-difluoromethylornithine prior to administration of 14C-putrescine.
Topics: Animals; Brain; Carbon Radioisotopes; Eflornithine; Lung; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Ornithine; Putrescine; Tissue Distribution | 1983 |
Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; DNA, Neoplasm; Eflornithine; Molecular Conformation; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Viscosity | 1983 |
Effects of alpha-difluoromethylornithine and 5-fluorouracil on the proliferation of a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Survival; Eflornithine; Fluorouracil; Humans; Kinetics; Ornithine; Putrescine; Spermidine | 1983 |
Inhibition of DNA and protein synthesis in UV-irradiated mouse skin by 2-difluoromethylornithine, methylglyoxal bis(guanylhydrazone), and their combination.
Topics: Animals; DNA Replication; Drug Interactions; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Protein Biosynthesis; Putrescine; Skin; Spermidine; Ultraviolet Rays | 1983 |
Polyamine biosynthesis is required for the maintenance of peripheral blood cell elements in the rat.
Topics: Animals; Blood Cell Count; Blood Platelets; Bone Marrow; Carboxy-Lyases; Cytarabine; Eflornithine; Erythrocytes; Female; Leukocytes; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains | 1983 |
Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation.
Topics: Animals; Carboxy-Lyases; Cell Differentiation; Cell Line; Eflornithine; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Teratoma | 1983 |
Inhibition of rat embryonic development by the intrauterine administration of alpha-difluoromethylornithine.
Topics: Animals; Contraceptives, Postcoital; Contraceptives, Postcoital, Synthetic; Eflornithine; Embryo Implantation; Embryo, Mammalian; Female; Ornithine; Ornithine Decarboxylase Inhibitors; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Uterus | 1983 |
Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an orn
Topics: Aged; Cadaverine; Chromatography, High Pressure Liquid; Eflornithine; Female; Fluorescence; Humans; Male; Middle Aged; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1983 |
Blood brain barrier breakdown in brain edema following cold injury is mediated by microvascular polyamines.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Cortex; Cerebrovascular Circulation; Eflornithine; Female; Freezing; Kinetics; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains | 1983 |
Differential effect of alpha-difluoromethylornithine on the in vivo uptake of 14C-labeled polyamines and methylglyoxal bis(guanylhydrazone) by a rat prostate-derived tumor.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Eflornithine; Guanidines; Male; Mitoguazone; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Rats; Rats, Inbred Strains; Spermidine | 1984 |
Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Eflornithine; Fibroblasts; Mice; Ornithine; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; Diazepam; Dimethyl Sulfoxide; Eflornithine; Kinetics; Leukemia, Experimental; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Inhibition of platelet aggregation and endogenous lectin activity by oligoamines.
Topics: Amino Acids; Animals; Cattle; Dose-Response Relationship, Drug; Hemagglutination Tests; Histidine; Humans; Lectins; Lysine; Ornithine; Platelet Aggregation; Putrescine; Serotonin; Spermidine; Spermine; Thrombin | 1984 |
Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells.
Topics: Animals; Cell Division; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Eflornithine; Liver Neoplasms, Experimental; Macromolecular Substances; Neoplasm Proteins; Ornithine; Polyribosomes; Putrescine; Rats; Spermidine; Spermine | 1984 |
Transfer of intestine-derived diamines into tumour cells during treatment of Ehrlich-ascites--carcinoma-bearing mice with polyamine anti-metabolites.
Topics: Animals; Cadaverine; Carcinoma, Ehrlich Tumor; Diamines; Eflornithine; Guanidines; Mice; Mitoguazone; Ornithine; Putrescine | 1984 |
Involvement of spermidine in proliferation and differentiation of human promyelocytic leukemia cells.
Topics: Acetamides; Antineoplastic Agents; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Humans; Leukemia, Myeloid, Acute; Ornithine; Putrescine; Spermidine; Spermine | 1984 |
Time dependence of the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity caused by alpha-difluoromethylornithine-induced polyamine depletion in 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Drug Synergism; Eflornithine; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine | 1984 |
Mode of interaction of ornithine decarboxylase with antizyme and alpha-difluoromethylornithine.
Topics: Animals; Eflornithine; Enzyme Inhibitors; Female; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Proteins; Putrescine; Rats | 1984 |
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Polyamines as mediators of estrogen action on the growth of experimental breast cancer in rats.
Topics: Animals; Cell Aggregation; Eflornithine; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
The mechanism of hepatoprotection by epsilon aminocaproic acid and putrescine.
Topics: Aminocaproates; Aminocaproic Acid; Animals; Chemical and Drug Induced Liver Injury; Eflornithine; Galactosamine; Liver Diseases; Necrosis; Ornithine; Ornithine Decarboxylase Inhibitors; Protease Inhibitors; Putrescine; Rats; Rats, Inbred Strains; Urokinase-Type Plasminogen Activator | 1984 |
Polyamine biosynthetic enzymes as targets in cancer chemotherapy.
Topics: Adenine Nucleotides; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; Eflornithine; Enzyme Inhibitors; Methionine; Mice; Ornithine; Putrescine; Spermidine; Spermine; Teratoma | 1984 |
Role of polyamine synthesis in the stimulation of hexose transport by epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate in cultured mouse fibroblasts.
Topics: Animals; Cells, Cultured; Deoxyglucose; Eflornithine; Epidermal Growth Factor; Fibroblasts; Hexoses; Mice; Ornithine; Polyamines; Putrescine; Tetradecanoylphorbol Acetate | 1984 |
Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
Topics: Animals; Animals, Newborn; Brain; Cyclohexylamines; Dose-Response Relationship, Drug; Eflornithine; Female; Heart; Male; Myocardium; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermidine Synthase; Spermine; Transferases | 1984 |
Putrescine biosynthesis in Tetrahymena thermophila.
Topics: Agmatine; Arginine; Carbon Dioxide; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine; Pyridoxal Phosphate; Tetrahymena | 1984 |
Inhibition of growth of human or hamster pancreatic cancer cell lines by alpha-difluoromethylornithine alone and combined with cis-diamminedichloroplatinum(II).
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Cisplatin; Cricetinae; Drug Evaluation, Preclinical; Drug Interactions; Eflornithine; Humans; Kinetics; Ornithine; Pancreatic Neoplasms; Putrescine | 1984 |
Polyamines and the development of monocrotaline-induced pulmonary hypertension.
Topics: Adenosylmethionine Decarboxylase; Animals; Blood Pressure; Eflornithine; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kinetics; Lung; Male; Monocrotaline; Ornithine; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Polyamines; Putrescine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Spermidine; Spermine | 1984 |
Reversal of the growth inhibitory effect of alpha-difluoromethylornithine by putrescine but not by other divalent cations.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Diamines; Eflornithine; Kinetics; Magnesium; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Structure-Activity Relationship | 1984 |
Polyamines and pancreatic growth induced by caerulein.
Topics: Animals; Ceruletide; DNA; Eflornithine; Male; Organ Size; Ornithine; Pancreas; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1984 |
Regulation of polyamine synthesis in relation to putrescine and spermidine pools in Neurospora crassa.
Topics: Arginine; Kinetics; Neurospora; Neurospora crassa; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1981 |
Metabolic sequestration of putrescine in Neurospora crassa.
Topics: Carbon Radioisotopes; Kinetics; Neurospora; Neurospora crassa; Ornithine; Putrescine; Radioisotope Dilution Technique; Spermidine; Spermine | 1982 |
A role for ornithine in the regulation of putrescine accumulation and ornithine decarboxylase activity in Reuber H35 hepatoma cells.
Topics: Animals; Arginase; Arginine; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Liver Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Putrescine; Tetradecanoylphorbol Acetate | 1984 |
Inhibition of polyamine synthesis and proliferation in mouse L cells by DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Deoxyadenine Nucleotides; DNA; L Cells; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Thymine Nucleotides | 1983 |
alpha-(Fluoromethyl)dehydroornithine and alpha-(fluoromethyl)dehydroputrescine analogues as irreversible inhibitors of ornithine decarboxylase.
Topics: Animals; Eflornithine; Indicators and Reagents; Isomerism; Kinetics; Liver; Magnetic Resonance Spectroscopy; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Structure-Activity Relationship | 1983 |
On the nonoccurrence of ornithine decarboxylase in nerve endings.
Topics: Animals; Brain; Carbon Dioxide; Carboxy-Lyases; Centrifugation, Density Gradient; Mice; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Putrescine; Rats; Synaptosomes | 1980 |
Catabolism of L-arginine by Pseudomonas aeruginosa.
Topics: Agmatine; Arginine; Carboxy-Lyases; Enzyme Induction; Enzyme Repression; Ornithine; Pseudomonas aeruginosa; Putrescine | 1980 |
Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.
Topics: Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cell Division; Eflornithine; Kinetics; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1980 |
Polyamine depletion induces enhanced synthesis and accumulation of cadaverine in cultured Ehrlich ascites carcinoma cells.
Topics: Animals; Cadaverine; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cells, Cultured; Diamines; Eflornithine; Female; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine | 1980 |
Metabolism of 1-14C-ornithine and 1,4-14C-putrescine in chronically uremic and control rats.
Topics: Animals; Carbon Dioxide; Chronic Disease; Female; Kidney; Liver; Muscles; Nephrectomy; Ornithine; Putrescine; Rats; Uremia | 1980 |
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines; Putrescine; Radiation Tolerance; Rats; Spermidine; Spermine; X-Rays | 1980 |
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Interphase; Ornithine; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1981 |
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Ovulation; Pregnancy; Putrescine; Rats; Spermidine; Spermine | 1980 |
Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Mitoguazone; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine | 1980 |
Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Eflornithine; Female; Guanidines; Humans; Iodoacetates; Iodoacetic Acid; Leukemia, Lymphoid; Mice; Mitoguazone; Ornithine; Putrescine; Spermine | 1981 |
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Eflornithine; Glioma; Kinetics; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats | 1981 |
Aminoguanidine reversal of the inhibitory effects of ornithine analogs on the in vitro clonogenic survival of the R3327AT prostate-derived tumor.
Topics: Amine Oxidase (Copper-Containing); Animals; Carboxy-Lyases; Cell Line; Eflornithine; Guanidines; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Prostatic Neoplasms; Putrescine; Rats | 1981 |
Polyamines are needed for the differentiation of 3T3-L1 fibroblasts into adipose cells.
Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Eflornithine; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine | 1981 |
Decarboxylation of ornithine and lysine by ornithine decarboxylase from kidneys of testosterone treated mice.
Topics: Animals; Cadaverine; Carboxy-Lyases; Eflornithine; Kidney; Lysine; Male; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Testosterone | 1981 |
Effect of alpha-difluoromethylornithine on polyamine and DNA synthesis in regenerating rat liver: reversal of inhibition of DNA synthesis by putrescine.
Topics: Animals; DNA; Eflornithine; Liver; Liver Regeneration; Male; Ornithine; Polyamines; Putrescine; Rats | 1982 |
Decreased cytotoxicity of cis-diamminedichloroplatinum(II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cisplatin; DNA; Eflornithine; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats | 1982 |
Formation and interconversion of putrescine and spermidine in mammalian cells.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Cell Line; Eflornithine; Enzyme Activation; Enzyme Repression; Liver; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine | 1980 |
Effects of inhibitors of ornithine and S-adenosylmethionine decarboxylases on L6 myoblast proliferation.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Eflornithine; Mitoguazone; Muscles; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1982 |
Effect of epidermal polyamine depletion on the accumulation of methylglyoxal bis(guanylhydrazone) in mouse skin.
Topics: Animals; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Polyamines; Putrescine; Skin; Skin Physiological Phenomena; Spermidine | 1982 |
Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Iodoacetates; Iodoacetic Acid; Mice; Mitoguazone; Neoplasms, Experimental; Ornithine; Ouabain; Polyamines; Putrescine; Spermidine | 1981 |
Accumulation of decarboxylated S-adenosyl-L-methionine in mammalian cells as a consequence of the inhibition of putrescine biosynthesis.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cells, Cultured; Eflornithine; Liver Neoplasms, Experimental; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Putrescine; Rats; Rats, Inbred Strains | 1982 |
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1982 |
An essential role for polyamine biosynthesis during human granulopoietic differentiation.
Topics: Bone Marrow; Cell Differentiation; Cells, Cultured; Culture Media; Eflornithine; Granulocytes; Humans; Macrophages; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine | 1982 |
Replacement of natural polyamines by cadaverine and its aminopropyl derivatives in Ehrlich ascites carcinoma cells.
Topics: Animals; Cadaverine; Carcinoma, Ehrlich Tumor; Cell Division; Diamines; DNA Replication; Eflornithine; Kinetics; Mice; Ornithine; Protein Biosynthesis; Putrescine; Structure-Activity Relationship; Transcription, Genetic | 1982 |
Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
Topics: Animals; Animals, Newborn; Brain; Carboxy-Lyases; Eflornithine; Female; Heart; Kidney; Myocardium; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Pregnancy; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1982 |
Polyamine depletion influences drug-induced chromosomal damage.
Topics: Animals; Carmustine; Chromosomes; Cisplatin; DNA; Eflornithine; Nucleic Acid Conformation; Ornithine; Polyamines; Putrescine; Rats; Sister Chromatid Exchange; Spermidine; Spermine | 1982 |
Difluoromethylornithine enhancement of putrescine uptake into the prostate: concise communication.
Topics: Animals; Castration; Eflornithine; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Prostate; Putrescine; Rats; Rats, Inbred Strains; Rats, Inbred WF | 1982 |
Delayed sensitization to heat by inhibitors of polyamine-biosynthetic enzymes.
Topics: Animals; Carboxy-Lyases; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; Eflornithine; Female; Guanidines; Hot Temperature; Kinetics; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Putrescine | 1982 |
alpha-Difluoromethylornithine: a promising lead for preventive chemotherapy for coccidiosis.
Topics: Animals; Cecal Diseases; Chickens; Coccidiosis; Coccidiostats; Eflornithine; Eimeria; Male; Ornithine; Poultry Diseases; Putrescine | 1982 |
Role of polyamines in expression of the differentiated phenotype of chondrocytes: effect of DL-alpha-hydrazino-delta-aminovaleric acid (DL-HAVA), an inhibitor of ornithine decarboxylase, on chondrocytes treated with parathyroid hormone.
Topics: Animals; Carboxy-Lyases; Cartilage; Cell Differentiation; Cells, Cultured; DNA Replication; Kinetics; Male; Ornithine; Ornithine Decarboxylase Inhibitors; Parathyroid Hormone; Peptide Fragments; Polyamines; Putrescine; Rabbits; Spermidine; Spermine; Teriparatide | 1983 |
Arginase activity of different cells in tissue culture.
Topics: Animals; Arginase; Cell Line; Chick Embryo; Culture Techniques; Female; Fibroblasts; Fibrosarcoma; HeLa Cells; Humans; Mice; Ornithine; Ornithine Decarboxylase; Pregnancy; Putrescine; Rhabdomyosarcoma | 1983 |
[Ornithine decarboxylating activity of salivary microorganisms].
Topics: Bacteria; Humans; Hydrogen-Ion Concentration; Ornithine; Ornithine Decarboxylase; Putrescine; Saliva | 1982 |
Putrescine and the regulation of S-adenosyl-L-methionine decarboxylase in cultured mouse mammary gland.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Enzyme Activation; Female; Hypotonic Solutions; Insulin; Mammary Glands, Animal; Mice; Organ Culture Techniques; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine | 1980 |
Regulation of tRNA methyltransferase activities by spermidine and putrescine. Inhibition of polyamine synthesis and tRNA methylation by alpha-methylornithine or 1,3-diaminopropan-2-ol in Dictyostelium.
Topics: Diamines; Dictyostelium; Methylation; Nucleosides; Ornithine; Propanolamines; Putrescine; RNA, Transfer; Spermidine; tRNA Methyltransferases | 1982 |
Posttranslationally modified ornithine decarboxylase may regulate RNA polymerase I activity.
Topics: Animals; Carboxy-Lyases; Cell Nucleus; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Guinea Pigs; Kinetics; Liver; Macromolecular Substances; Magnesium; Ornithine; Ornithine Decarboxylase; Protein Processing, Post-Translational; Putrescine; Rats; RNA Polymerase I | 1982 |
Affinity of putrescine, spermidine and spermine for pigmented tissues.
Topics: Animals; Cattle; Eye; Kidney; Liver; Male; Melanins; Melanocytes; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Putrescine; Species Specificity; Spermidine; Spermine; Tissue Distribution | 1982 |
Induction of polyamine limitation in Chinese hamster ovary cells by alpha-methylornithine.
Topics: Animals; Cell Division; Cricetinae; Cricetulus; Female; Ornithine; Ovary; Polyamines; Putrescine; Spermidine | 1981 |
Putrescine turnover in kidneys of testosterone-treated mice.
Topics: Animals; Cadaverine; Castration; Guanidines; Kidney; Male; Mice; Organ Size; Ornithine; Putrescine; Spermidine; Testosterone | 1981 |
A possible role of arginase in the regulation of polyamine biosynthesis in the rat thyroid.
Topics: Amino Acids; Animals; Arginase; Arginine; DNA; Male; Methylthiouracil; Ornithine; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Thyroid Gland; Thyrotropin | 1981 |
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1980 |
Inhibition of Dugesia tigrina auricle regeneration by inhibitors of polyamine synthesis.
Topics: Aldehydes; Animals; Ornithine; Polyamines; Putrescine; Pyruvaldehyde; Regeneration; Spermidine; Spermine; Turbellaria | 1980 |
Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase.
Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Enzyme Inhibitors; Liver; Liver Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Structure-Activity Relationship; Thioacetamide; Tumor Cells, Cultured | 1995 |
Polyamine metabolism in the rat liver after orthotopic liver transplantation.
Topics: Acetyltransferases; Alanine Transaminase; Animals; Aspartate Aminotransferases; DNA; Genes, myc; Graft Survival; Kinetics; L-Lactate Dehydrogenase; Liver; Liver Transplantation; Male; Malondialdehyde; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine | 1995 |
Metabolism of L-arginine through polyamine and nitric oxide synthase pathways in proliferative or differentiated human colon carcinoma cells.
Topics: Adenocarcinoma; Arginine; Cell Differentiation; Cell Division; Colonic Neoplasms; Dipeptidyl Peptidase 4; Glutamine; Humans; Nitric Oxide Synthase; Ornithine; Polyamines; Putrescine; Tumor Cells, Cultured | 1995 |
Transglutaminase activity in enterocytes isolated from pig jejunum.
Topics: Animals; Arginine; Calcium; Cell Separation; Glutamine; Glycine; Jejunum; Kinetics; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Swine; Temperature; Transglutaminases | 1995 |
Polyamine transport and arginine pool size in vascular endothelial cells.
Topics: Animals; Aorta; Arginine; Biological Transport; Cells, Cultured; Endothelium, Vascular; Humans; Kinetics; Ornithine; Polyamines; Putrescine; Swine; Tritium; Umbilical Veins | 1994 |
Arginine and ornithine metabolizing enzymes in testosterone-induced hypertrophic mouse kidney.
Topics: Animals; Arginase; Arginine; Eflornithine; Enzyme Induction; Female; Folic Acid; Hypertrophy; Kidney; Male; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Putrescine; Quinazolines; Sex Factors; Testosterone | 1995 |
Fluorinated analogues of L-ornithine are powerful inhibitors of ornithine decarboxylase and cell growth of Leishmania infantum promastigotes.
Topics: Animals; Anthelmintics; Cell Division; Dose-Response Relationship, Drug; Eflornithine; Kinetics; Leishmania infantum; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine | 1995 |
Enhanced endogenous ornithine concentrations protect against tonic seizures and coma in acute ammonia intoxication.
Topics: 3-Mercaptopropionic Acid; Ammonia; Animals; Brain Chemistry; Coma; Dialysis; Dizocilpine Maleate; Electroshock; Epilepsy, Generalized; Female; Glutamate-Ammonia Ligase; Methionine Sulfoximine; Mice; N-Methylaspartate; Ornithine; Ornithine-Oxo-Acid Transaminase; Pentylenetetrazole; Postural Balance; Putrescine; Strychnine | 1993 |
Biosynthesis and selective export of 1,5-diaminopentane (cadaverine) in mycoplasma-free cultured mammalian cells.
Topics: Amino Acids; Animals; Biological Transport; Cadaverine; Carcinoma, Hepatocellular; Cell Line; Culture Media; Eflornithine; Insulin; Kinetics; Lipopolysaccharides; Lysine; Mice; Mycoplasma; Ornithine; Putrescine; Rats; Spectrometry, Mass, Fast Atom Bombardment; Tumor Cells, Cultured | 1994 |
Regulation of putrescine export in lipopolysaccharide or IFN-gamma-activated murine monocytic-leukemic RAW 264 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; DNA; Dose-Response Relationship, Drug; Eflornithine; Inflammation; Interferon-gamma; Leukemia, Myeloid; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Ornithine; Ornithine Decarboxylase; Putrescine; Tumor Cells, Cultured; Verapamil | 1994 |
Endothelial polyamine uptake: selective stimulation by L-arginine deprivation or polyamine depletion.
Topics: Animals; Arginine; Biological Transport; Eflornithine; Endothelium, Vascular; Ornithine; Polyamines; Putrescine; Swine; Time Factors | 1994 |
Selective putrescine export is regulated by insulin and ornithine in Reuber H35 hepatoma cells.
Topics: Animals; Biological Transport; Culture Media; Insulin; Liver Neoplasms, Experimental; Ornithine; Putrescine; Rats; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Verapamil | 1994 |
Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain.
Topics: Animals; Brain; Differential Threshold; Electroshock; Escape Reaction; Immunohistochemistry; Learning; Mice; Mice, Transgenic; Motor Activity; Ornithine; Ornithine Decarboxylase Inhibitors; Pentylenetetrazole; Polyamines; Putrescine; Reference Values; Seizures; Space Perception; Swimming | 1993 |
Polyamines in Trypanosoma cruzi.
Topics: Agmatine; Animals; Arginine; Carboxy-Lyases; Eflornithine; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protozoan Proteins; Putrescine; Trypanosoma cruzi | 1993 |
Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines.
Topics: Animals; Brain; Diamines; Gene Expression; Male; Mice; Mice, Transgenic; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Polyamines; Putrescine; Spermidine; Spermine; Testis | 1993 |
Toxicity and growth-promoting potential of spermine when fed to chicks.
Topics: Adenosylmethionine Decarboxylase; Animal Feed; Animals; Chickens; Cysteine; Diet; Dose-Response Relationship, Drug; Eating; Glutathione; Kidney; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Pyrrolidonecarboxylic Acid; Spermine; Thiazoles; Thiazolidines | 1995 |
Polyamine changes in the vestibular nuclei of guinea pigs following labyrinthectomy.
Topics: Amino Acids; Animals; Brain Stem; Chromatography, High Pressure Liquid; Ear, Inner; Guinea Pigs; Image Processing, Computer-Assisted; Ornithine; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Vestibular Nuclei | 1994 |
Circular dichroism assay for decarboxylation of optically pure amino acids: application to ornithine decarboxylase.
Topics: Cell Line; Circular Dichroism; Decarboxylation; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine; Stereoisomerism | 1996 |
Exposure to ornithine results in excessive accumulation of putrescine and apoptotic cell death in ornithine decarboxylase overproducing mouse myeloma cells.
Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Biogenic Polyamines; Cell Size; Cell Survival; Cycloheximide; DNA; Enzyme Inhibitors; Guanidines; Mercaptoethanol; Mice; Multiple Myeloma; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Protein Biosynthesis; Protein Synthesis Inhibitors; Putrescine; Tumor Cells, Cultured | 1995 |
Substrate specificity of lentil seedling amine oxidase.
Topics: Amine Oxidase (Copper-Containing); Amines; Amino Acids; Fabaceae; Lysine; Ornithine; Oxidation-Reduction; Plant Proteins; Plants, Medicinal; Putrescine; Seeds; Spectrum Analysis; Substrate Specificity | 1996 |
Astrocytes, not neurons, show most prominent staining for spermidine/spermine-like immunoreactivity in adult rat brain.
Topics: Animals; Antibody Specificity; Arginine; Astrocytes; Brain; Brain Chemistry; Enzyme-Linked Immunosorbent Assay; Ethanolamine; Ethanolamines; Female; Histamine; Immunohistochemistry; Lysine; Male; Neurons; Ornithine; Putrescine; Rats; Rats, Inbred Lew; Spermidine | 1997 |
Excretion and uptake of putrescine by the PotE protein in Escherichia coli.
Topics: Amino Acid Sequence; Antiporters; Bacterial Proteins; Biological Transport; Cell-Free System; Escherichia coli; Escherichia coli Proteins; Glutamates; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Ornithine; Putrescine; Structure-Activity Relationship | 1997 |
Tolerance to putrescine toxicity in Chinese hamster ovary cells is associated with altered uptake and export.
Topics: Amine Oxidase (Copper-Containing); Animals; Biological Transport; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Drug Resistance; Drug Tolerance; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine | 1997 |
Enteral supplementation with ornithine alpha ketoglutarate improves the early adaptive response to resection.
Topics: Adaptation, Biological; Animals; Blotting, Northern; Caseins; Enteral Nutrition; Food, Fortified; Hyperplasia; Ileum; Jejunostomy; Male; Ornithine; Postoperative Period; Protein Hydrolysates; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine; Sucrase | 1997 |
Cell cycle parameters of Chinese hamster ovary cells during exponential, polyamine-limited growth.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; CHO Cells; Cricetinae; Female; Ornithine; Ovary; Polyamines; Putrescine | 1981 |
Polyamine metabolism in the thermotolerant mesophilic fungus Aspergillus fumigatus.
Topics: Adenosylmethionine Decarboxylase; Aspergillus fumigatus; Cadaverine; Carboxy-Lyases; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine; Temperature | 1997 |
Lysophosphatidylcholine regulates cationic amino acid transport and metabolism in vascular smooth muscle cells. Role in polyamine biosynthesis.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Animals; Arginase; Arginine; Biological Transport; Carrier Proteins; Gene Expression; Lysophosphatidylcholines; Membrane Proteins; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; RNA, Messenger | 1997 |
Metabolism of polyamines in transgenic cells of carrot expressing a mouse ornithine decarboxylase cDNA.
Topics: Animals; Arginine; Biological Transport; Cell Line; Daucus carota; DNA, Complementary; Mice; Ornithine; Ornithine Decarboxylase; Plants, Genetically Modified; Polyamines; Putrescine; Recombinant Proteins; Spermidine; Spermine; Transfection | 1998 |
Determination of ornithine decarboxylase activity using [3H]ornithine.
Topics: Blotting, Western; Carbon Dioxide; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Immunohistochemistry; Ornithine; Ornithine Decarboxylase; Precipitin Tests; Putrescine; Radiometry; RNA, Messenger; Tritium | 1998 |
Effects of L-valine on growth and polyamine metabolism in human colon carcinoma cells.
Topics: Arginine; Cell Differentiation; Cell Division; Cell Survival; Glutamine; HT29 Cells; Humans; Ornithine; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Valine | 1998 |
Thrombin stimulates vascular smooth muscle cell polyamine synthesis by inducing cationic amino acid transporter and ornithine decarboxylase gene expression.
Topics: Amino Acid Transport Systems, Basic; Animals; Aorta, Thoracic; Biological Transport; Carrier Proteins; Cell Division; Cells, Cultured; Eflornithine; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Male; Membrane Proteins; Muscle Proteins; Muscle, Smooth, Vascular; omega-N-Methylarginine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; RNA, Messenger; Thrombin | 1998 |
NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
Topics: Animals; Aorta; Arginase; Arginine; Caco-2 Cells; Cell Division; Coculture Techniques; DNA; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Donors; Ornithine; Ornithine Decarboxylase; Oxadiazoles; Polyamines; Putrescine; Quinoxalines; Rats; Spermidine; Spermine; Thymidine; Triazenes; Urea | 1998 |
Biogenic amine production by Lactobacillus.
Topics: Agmatine; Arginine; Beverages; Citrus; Lactobacillus; Ornithine; Putrescine; Wine | 2001 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body Weight; Cell Division; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Colonic Polyps; Disease Progression; Fasting; Hyperplasia; Male; Neoplasm Proteins; Ornithine; Ornithine Decarboxylase; Polyamines; Precancerous Conditions; Putrescine; Rats; Rats, Wistar; Sensitivity and Specificity; Spermidine; Spermine | 2000 |
Antifungal activity of three spermidine conjugates.
Topics: Antifungal Agents; Ascomycota; Avena; Culture Media; Food Microbiology; Hordeum; Ornithine; Pollen; Putrescine; Spermidine; Spermine | 2001 |
Synthesis of putrescine under possible primitive Earth conditions.
Topics: Decarboxylation; Earth, Planet; Ornithine; Putrescine | 1991 |
Arginine decarboxylase as the source of putrescine for tobacco alkaloids.
Topics: Alkaloids; Arginine; Carboxy-Lyases; Eflornithine; Enzyme Inhibitors; Nicotiana; Nicotine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Toxic; Putrescine; Pyrrolidines | 1986 |
Activities of arginase I and II are limiting for endothelial cell proliferation.
Topics: Animals; Arginase; Cattle; Cell Division; Cells, Cultured; Coronary Vessels; Eflornithine; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Isoenzymes; Lac Operon; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Transfection | 2002 |
Genetic manipulation of the metabolism of polyamines in poplar cells. The regulation of putrescine catabolism.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amine Oxidase (Copper-Containing); Animals; Carbon Radioisotopes; Cell Line; Glutamate Decarboxylase; Mice; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Plants, Genetically Modified; Polyamines; Putrescine; Salicaceae; Spermidine | 2002 |
Polyamine participation in the maturation of glycoprotein fucosylation, but not sialylation, in rat small intestine.
Topics: Amine Oxidase (Copper-Containing); Animal Feed; Animals; Animals, Suckling; beta-D-Galactoside alpha 2-6-Sialyltransferase; Enzyme Induction; Enzyme Inhibitors; Glycoproteins; Glycosylation; Intestinal Mucosa; Intestine, Small; Male; Microvilli; Milk; Ornithine; Protein Processing, Post-Translational; Proteins; Putrescine; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Sialyltransferases; Spermidine; Spermine; Transcription, Genetic; Weaning | 2002 |
Arginase I induction in macrophages, triggered by Th2-type cytokines, supports the growth of intracellular Leishmania parasites.
Topics: Animals; Arginase; Arginine; Cytokines; Interleukin-10; Interleukin-4; Leishmania major; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ornithine; Putrescine; Th2 Cells; Transforming Growth Factor beta | 2002 |
Comparative uptake of polyamines by prostate and non-prostate cancer cell lines.
Topics: Animals; Breast Neoplasms; Carbon Radioisotopes; Humans; Male; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats; Reproducibility of Results; Sensitivity and Specificity; Spermidine; Spermine; Tumor Cells, Cultured; Urogenital Neoplasms | 2002 |
Prostaglandin-independent effects of aspirin on cell cycle and putrescine synthesis in human colon carcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Caco-2 Cells; Cell Cycle; Cell Membrane; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; HT29 Cells; Humans; Isoenzymes; Membrane Proteins; Ornithine; Polyamines; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Putrescine | 2003 |
Polyamine homeostasis in transgenic plants overexpressing ornithine decarboxylase includes ornithine limitation.
Topics: Cells, Cultured; Datura stramonium; DNA, Complementary; Flowers; Gene Expression; Homeostasis; Nicotiana; Ornithine; Ornithine Decarboxylase; Plant Leaves; Plants, Genetically Modified; Polyamines; Putrescine; RNA, Messenger; RNA, Plant | 2003 |
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.
Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosylmethionine Decarboxylase; Carcinoma; Cell Division; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Humans; Male; Methionine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prostatic Neoplasms; Putrescine; RNA, Messenger; S-Adenosylmethionine; Tetracyclines; Thionucleosides; Tumor Cells, Cultured | 2004 |
Endogenous polyamine levels in macrophages is sufficient to support growth of Toxoplasma gondii.
Topics: Animals; Carboxy-Lyases; Cells, Cultured; Chlorocebus aethiops; Host-Parasite Interactions; Macrophages, Peritoneal; Male; Mice; Nitric Oxide; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Toxoplasma; Vero Cells | 2004 |
Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase.
Topics: Alanine; Animals; Binding Sites; Crystallization; Crystallography, X-Ray; Diamines; Dimerization; Kinetics; Lysine; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Protein Conformation; Putrescine; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Trypanosoma brucei brucei | 2004 |
Polyamine synthesis from proline in the developing porcine placenta.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amniotic Fluid; Animals; Arginase; Carbon Radioisotopes; Female; Fetal Development; Male; Methionine; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Placenta; Placentation; Polyamines; Pregnancy; Proline; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Sus scrofa | 2005 |
Localization and differential expression of arginase II in the kidney of male and female mice.
Topics: Animals; Arginase; Arginine; Carbon Radioisotopes; Cytosol; Female; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutamine; Kidney Tubules; Male; Mice; Mice, Inbred Strains; Mitochondria; Molecular Sequence Data; Ornithine; Putrescine; RNA, Messenger; Sex Characteristics; Urea | 2005 |
The first archaeal agmatinase from anaerobic hyperthermophilic archaeon Pyrococcus horikoshii: cloning, expression, and characterization.
Topics: Amino Acid Sequence; Archaeal Proteins; Arginine; Cloning, Molecular; Humans; Hydrogen-Ion Concentration; Ornithine; Phylogeny; Putrescine; Pyrococcus horikoshii; Recombinant Proteins; Sequence Alignment; Temperature; Ureohydrolases | 2005 |
Dependence of transition state structure on substrate: the intrinsic C-13 kinetic isotope effect is different for physiological and slow substrates of the ornithine decarboxylase reaction because of different hydrogen bonding structures.
Topics: Carbon Isotopes; Hydrogen Bonding; Kinetics; Models, Molecular; Ornithine; Ornithine Decarboxylase; Putrescine; Quantum Theory; Substrate Specificity; Thermodynamics | 2005 |
Putrescine accumulation in wine: role of Oenococcus oeni.
Topics: Gram-Positive Cocci; Ornithine; Putrescine; Spermidine; Wine | 2005 |
Genetic manipulation of a primary metabolic pathway for L-ornithine production in Escherichia coli.
Topics: Amino-Acid N-Acetyltransferase; Arabinose; Biotechnology; Citrulline; Dose-Response Relationship, Drug; Escherichia coli; Genetic Engineering; Genetic Techniques; Models, Biological; Models, Genetic; Ornithine; Phenotype; Plasmids; Promoter Regions, Genetic; Putrescine | 2006 |
Liver I/R injury is improved by the arginase inhibitor, N(omega)-hydroxy-nor-L-arginine (nor-NOHA).
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Biogenic Polyamines; Liver; Liver Transplantation; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Putrescine; Rats; Rats, Inbred Lew; Reperfusion Injury; Spermidine; Spermine | 2007 |
Divergent polyamine metabolism in the Apicomplexa.
Topics: Animals; Apicomplexa; Arginine; Carbamyl Phosphate; Citrulline; Fibroblasts; Foreskin; Genome, Protozoan; Humans; Male; Ornithine; Polyamines; Putrescine; Spermidine; Toxoplasma | 2007 |
Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells.
Topics: Animals; Cationic Amino Acid Transporter 1; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibitors; Epithelial Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ornithine-Oxo-Acid Transaminase; Pigment Epithelium of Eye; Proto-Oncogene Proteins c-myc; Putrescine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermidine; Spermine; Swine; Telomerase; Time Factors; Transfection; Up-Regulation | 2007 |
Phenotypic and genotypic analysis of amino acid auxotrophy in Lactobacillus helveticus CNRZ 32.
Topics: Amino Acids; Asparagine; Aspartic Acid; Citric Acid; Genome, Bacterial; Genotype; Lactobacillus helveticus; Models, Biological; Ornithine; Ornithine Decarboxylase; Phenotype; Putrescine | 2008 |
Weissella halotolerans W22 combines arginine deiminase and ornithine decarboxylation pathways and converts arginine to putrescine.
Topics: Adenosine Triphosphate; Arginine; Decarboxylation; Hydrolases; Lactobacillus; Metabolic Networks and Pathways; Ornithine; Proton-Motive Force; Putrescine | 2009 |
Transgenic manipulation of a single polyamine in poplar cells affects the accumulation of all amino acids.
Topics: Amino Acids; Animals; Carbon; Cell Line; gamma-Aminobutyric Acid; Mice; Nitrogen; Ornithine; Ornithine Decarboxylase; Perchlorates; Plants, Genetically Modified; Populus; Putrescine; Solubility; Spermidine; Spermine; Statistics as Topic; Time Factors; Transgenes; Up-Regulation | 2010 |
Central L-ornithine, but not polyamines, induces a hypnotic effect in neonatal chicks under acute stress.
Topics: Animals; Behavior, Animal; Chickens; Hypnotics and Sedatives; Injections, Intraventricular; Male; Ornithine; Polyamines; Posture; Putrescine; Social Isolation; Spermidine; Spermine; Stress, Psychological; Time Factors; Vocalization, Animal | 2010 |
Origin of the putrescine-producing ability of the coagulase-negative bacterium Staphylococcus epidermidis 2015B.
Topics: Antiporters; Bacterial Proteins; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA, Bacterial; Escherichia coli Proteins; Lactococcus lactis; Molecular Sequence Data; Ornithine; Ornithine Decarboxylase; Plasmids; Polymerase Chain Reaction; Putrescine; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus epidermidis | 2010 |
Targeted projection NMR spectroscopy for unambiguous metabolic profiling of complex mixtures.
Topics: Arginine; Hippurates; Magnetic Resonance Spectroscopy; Molecular Structure; Ornithine; Putrescine; Reference Standards | 2010 |
Life without putrescine: disruption of the gene-encoding polyamine oxidase in Ustilago maydis odc mutants.
Topics: Gene Knockout Techniques; Genes, Fungal; Microbial Viability; Mutagenesis, Insertional; Ornithine; Osmotic Pressure; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Stress, Physiological; Ustilago; Virulence | 2010 |
Living with high putrescine: expression of ornithine and arginine biosynthetic pathway genes in high and low putrescine producing poplar cells.
Topics: Animals; Arginine; Cells, Cultured; Mice; Mice, Transgenic; Ornithine; Populus; Putrescine; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Polyamines are traps for reactive intermediates in furan metabolism.
Topics: Acetylcysteine; Aldehydes; Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Environmental Pollution; Furans; Glutamine; Glutathione; Hepatocytes; Humans; Liver; Lysine; Mass Spectrometry; Ornithine; Oxidation-Reduction; Putrescine; Pyrroles; Rats; Spermidine | 2011 |
Development and evaluation of a highly sensitive rapid response enzymatic nanointerfaced biosensor for detection of putrescine.
Topics: Amine Oxidase (Copper-Containing); Ascorbic Acid; Biosensing Techniques; Electrochemical Techniques; Electrodes; Enzymes, Immobilized; Ferrosoferric Oxide; Hydrogen Peroxide; Metal Nanoparticles; Ornithine; Putrescine | 2011 |
New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine.
Topics: Agmatine; Amino Acid Sequence; Biocatalysis; Carboxyl and Carbamoyl Transferases; Catalytic Domain; Crystallography, X-Ray; Enterococcus faecalis; Fermentation; Hydrolases; Models, Molecular; Molecular Sequence Data; Multigene Family; Ornithine; Ornithine Carbamoyltransferase; Protein Engineering; Protein Multimerization; Protein Structure, Secondary; Protein Subunits; Putrescine; Sequence Deletion; Substrate Specificity | 2012 |
Accelerated pentose utilization by Corynebacterium glutamicum for accelerated production of lysine, glutamate, ornithine and putrescine.
Topics: Aldose-Ketose Isomerases; Amino Acids; Biotechnology; Corynebacterium glutamicum; Culture Media; Fermentation; Genetic Engineering; Glutamic Acid; Lysine; Ornithine; Phosphotransferases (Alcohol Group Acceptor); Putrescine; Recombinant Proteins; Xylose | 2013 |
Three-component lysine/ornithine decarboxylation system in Lactobacillus saerimneri 30a.
Topics: Amino Acid Transport Systems; Cadaverine; Decarboxylation; Escherichia coli; Lactobacillus; Lysine; Ornithine; Ornithine Decarboxylase; Putrescine | 2013 |
Ornithine: the overlooked molecule in the regulation of polyamine metabolism.
Topics: Animals; Arabidopsis; Biosynthetic Pathways; Cadaverine; Carbon Isotopes; Carboxy-Lyases; DNA, Complementary; Genetic Vectors; Mice; Ornithine; Ornithine Decarboxylase; Plants, Genetically Modified; Polyamines; Putrescine; Radioactivity; Spermidine; Spermine | 2013 |
Dietary arginine affects energy metabolism through polyamine turnover in juvenile Atlantic salmon (Salmo salar).
Topics: Acetyltransferases; Adipose Tissue, White; Animals; Aquaculture; Arginine; Carnitine O-Palmitoyltransferase; Diet; Dietary Proteins; Dietary Supplements; Energy Metabolism; Enzyme Induction; Fish Proteins; Isoenzymes; Lipid Metabolism; Liver; Muscle, Skeletal; Ornithine; Ornithine Decarboxylase; Plant Proteins; Polyamines; Putrescine; Salmo salar | 2013 |
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses.
Topics: Agmatine; Animals; Carboxy-Lyases; Cationic Amino Acid Transporter 1; Citrulline; Embryo Implantation; Embryonic Development; Female; Mammals; Nitric Oxide Synthase Type III; Ornithine; Ornithine Decarboxylase; Pregnancy; Pregnancy, Animal; Putrescine; Sheep; Spermidine; Spermine; Ureohydrolases | 2014 |
Cloning, expression and characterization of the ornithine decarboxylase gene from Dictyostelium discoideum.
Topics: Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cells, Cultured; Cloning, Molecular; Dictyostelium; Gene Expression Regulation; Humans; Immunoenzyme Techniques; Molecular Sequence Data; Ornithine; Ornithine Decarboxylase; Phylogeny; Protein Conformation; Putrescine; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid | 2014 |
A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells.
Topics: Acetyltransferases; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cisplatin; Computational Biology; Drug Resistance, Neoplasm; Esophagus; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Metabolome; Models, Statistical; Neoplastic Stem Cells; Ornithine; Proteins; Putrescine; Spermidine; Spermine; Spermine Synthase; Transcriptome | 2016 |
Intracellular sources of ornithine for polyamine synthesis in endothelial cells.
Topics: Animals; Arginine; Cattle; Cells, Cultured; Cyclohexanecarboxylic Acids; Endothelial Cells; Ornithine; Putrescine; Spermidine | 2016 |
Insights into the Biogenic Amine Metabolic Landscape during Industrial Semidry Chinese Rice Wine Fermentation.
Topics: Acids; Arginine; Biogenic Amines; Chromatography, High Pressure Liquid; Ethanol; Fermentation; Lactic Acid; Lactobacillus; Ornithine; Oryza; Putrescine; Spermidine; Spermine; Wine | 2016 |
A Label-Free Continuous Fluorescence-Based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor.
Topics: Biological Assay; Cell Line; Eflornithine; Fluorescence; Fluorescent Dyes; HEK293 Cells; Humans; Kinetics; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Receptors, Artificial | 2017 |
Metabolic evolution and a comparative omics analysis of Corynebacterium glutamicum for putrescine production.
Topics: Biosynthetic Pathways; Corynebacterium glutamicum; Enterobacter cloacae; Gene Deletion; Metabolic Engineering; NADP; Ornithine; Ornithine Decarboxylase; Polymorphism, Single Nucleotide; Proteomics; Putrescine | 2018 |
Lactobacillus rossiae strain isolated from sourdough produces putrescine from arginine.
Topics: Arginine; Bacterial Proteins; Bread; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Lactobacillus; Multigene Family; Operon; Ornithine; Ornithine Decarboxylase; Phylogeny; Putrescine | 2018 |
Progesterone-associated arginine decline at luteal phase of menstrual cycle and associations with related amino acids and nuclear factor kB activation.
Topics: Adult; Amino Acids; Arginine; Citrulline; Female; Follicular Phase; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Luteal Phase; NF-kappa B p50 Subunit; Ornithine; Progesterone; Putrescine; Reference Values; Spermidine; Spermine; Transcription Factor RelA | 2018 |
Oral administration of l-ornithine increases the content of both collagen constituting amino acids and polyamines in mouse skin.
Topics: Administration, Oral; Amino Acids; Animals; Collagen; Male; Mice, Inbred ICR; Ornithine; Polyamines; Putrescine; Skin; Spermidine; Spermine | 2019 |
Engineering Tropane Alkaloid Production Based on Metabolic Characterization of Ornithine Decarboxylase in
Topics: Alkaloids; Atropa belladonna; Cytosol; Hydrogen-Ion Concentration; Kinetics; Metabolic Engineering; Ornithine; Ornithine Decarboxylase; Plant Roots; Plants, Genetically Modified; Putrescine; RNA Interference; Solanaceous Alkaloids; Tropanes | 2020 |
Using arterial-venous analysis to characterize cancer metabolic consumption in patients.
Topics: Acetylcarnitine; Adult; Aged; Agmatine; Biomarkers, Tumor; Blood; Blood Chemical Analysis; Blood Glucose; Blood Vessels; Brain Neoplasms; Female; Glioma; Glucose; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Male; Metabolomics; Middle Aged; Ornithine; Putrescine; Uridine Monophosphate; Young Adult | 2020 |
The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
Topics: A549 Cells; Animals; Antineoplastic Agents; Biocatalysis; Cell Survival; Female; High-Throughput Screening Assays; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Binding; Putrescine; Xenograft Model Antitumor Assays | 2020 |
Ornithine Decarboxylation System of Shewanella baltica Regulates Putrescine Production and Acid Resistance.
Topics: Decarboxylation; Ornithine; Putrescine; Shewanella | 2021 |
[Optimization of a cucurbit[6]uril-based real-time label-free method for analyzing the activity of ornithine decarboxylase].
Topics: Bridged-Ring Compounds; Imidazoles; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine | 2021 |
Systemic L-ornithine supplementation specifically increases ovarian putrescine levels during ovulation in mice†.
Topics: Animals; Chorionic Gonadotropin; Dietary Supplements; Drinking Water; Female; Humans; Mice; Ornithine; Ornithine Decarboxylase; Ovary; Ovulation; Putrescine | 2022 |
Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars.
Topics: Amino Acids; gamma-Aminobutyric Acid; Ornithine; Oryza; Proline; Putrescine; Pyrroles; Pyruvaldehyde; Salt Stress | 2022 |
Metabolic engineering of Aureobasidium melanogenum for the overproduction of putrescine by improved L-ornithine biosynthesis.
Topics: Aureobasidium; Metabolic Engineering; Ornithine; Putrescine; Saccharomyces cerevisiae; Siderophores | 2022 |
The importance of the urea cycle and its relationships to polyamine metabolism during ammonium stress in Medicago truncatula.
Topics: Amine Oxidase (Copper-Containing); Ammonium Compounds; Medicago truncatula; Ornithine; Polyamines; Putrescine; Spermidine; Urea | 2022 |
Evaluation of the Influence of Biosurface Design on the Interaction between the Regulatory Peptide RS1-reg and ODC1 Reveals a Membrane-Dependent Affinity Increase.
Topics: Glucose; Humans; Hypoglycemic Agents; Mitochondrial Membrane Transport Proteins; Monosaccharide Transport Proteins; Ornithine; Peptides; Putrescine | 2022 |
Advanced pathway engineering for phototrophic putrescine production.
Topics: Amino Acids; Arginine; Cadaverine; Carbon Dioxide; Carboxy-Lyases; Nylons; Ornithine; Ornithine Decarboxylase; Oxidoreductases; Polyamines; Putrescine | 2022 |
Fusobacterium nucleatum Metabolically Integrates Commensals and Pathogens in Oral Biofilms.
Topics: Arginine; Biofilms; Fusobacterium nucleatum; Humans; Microbiota; Ornithine; Periodontitis; Porphyromonas gingivalis; Putrescine | 2022 |
Brassinosteroids enhance resistance to manganese toxicity in Malus robusta Rehd. via modulating polyamines profile.
Topics: Brassinosteroids; Chlorophyll; Malus; Manganese; Ornithine; Ornithine Decarboxylase; Oxidoreductases; Polyamines; Putrescine; Soil; Spermine; Water | 2022 |
The Y430F mutant of Salmonella d-ornithine/d-lysine decarboxylase has altered stereospecificity and a putrescine allosteric activation site.
Topics: Allosteric Regulation; Carboxy-Lyases; Kinetics; Lysine; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Putrescine; Pyridoxal Phosphate; Salmonella | 2022 |
Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription.
Topics: Animals; Anti-Bacterial Agents; Colitis; Enterobacteriaceae Infections; Immunity, Innate; Interleukin-17; Interleukin-22; Mice; Nuclear Receptor Subfamily 1, Group F, Member 3; Ornithine; Ornithine Decarboxylase; Putrescine; Th17 Cells | 2022 |
Topics: Agmatine; Cheese; Humans; Lactobacillaceae; Levilactobacillus brevis; Ornithine; Polyamines; Putrescine | 2023 |