ornithine and phenylacetic acid

ornithine has been researched along with phenylacetic acid in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Allmaier, G; Arán, V; de Pedro, MA; Pittenauer, E; Quintela, JC1
Davies, NA; Hodges, SJ; Jalan, R; Wright, G1
Cobos, MJ; Fuskevåg, OM; Jalan, R; Kalstad, T; Kristiansen, RG; Maehre, H; Revhaug, A; Rose, CF; Ytrebø, LM1
Arranz, JA; Córdoba, J; Oria, M; Raguer, N; Riudor, E; Romero-Giménez, J1
Balasubramaniyan, V; Davies, NA; Habtesion, A; Jalan, R; Mookerjee, RP; Sharifi, Y; Sharma, V; Wright, G1
Vilchez, RA; Wang, X1
Bajaj, JS; Bukofzer, S; Devarakonda, KR; Jamil, K; Potthoff, A; Pyrsopoulos, N; Rahimi, RS; Ram Bhamidimarri, K; Safadi, R; Thabut, D; Wang, L1

Trials

1 trial(s) available for ornithine and phenylacetic acid

ArticleYear
Pharmacokinetics/pharmacodynamics of L-ornithine phenylacetate in overt hepatic encephalopathy and the effect of plasma ammonia concentration reduction on clinical outcomes.
    Clinical and translational science, 2022, Volume: 15, Issue:6

    Topics: Adult; Ammonia; Hepatic Encephalopathy; Humans; Ornithine; Phenylacetates

2022

Other Studies

6 other study(ies) available for ornithine and phenylacetic acid

ArticleYear
Structure of peptidoglycan from Thermus thermophilus HB8.
    Journal of bacteriology, 1995, Volume: 177, Issue:17

    Topics: Acetylglucosamine; Amino Acid Sequence; Amino Acids; Carbohydrate Sequence; Cell Membrane; Cell Wall; Chromatography, High Pressure Liquid; Mass Spectrometry; Molecular Sequence Data; Muramic Acids; Ornithine; Peptides; Peptidoglycan; Phenylacetates; Stereoisomerism; Thermus thermophilus

1995
L-Ornithine phenylacetate (OP): a novel treatment for hyperammonemia and hepatic encephalopathy.
    Medical hypotheses, 2007, Volume: 69, Issue:5

    Topics: Ammonia; Drug Therapy, Combination; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver; Models, Biological; Muscle, Skeletal; Ornithine; Phenylacetates

2007
L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:1

    Topics: Ammonia; Animals; Arteries; Brain; Drug Combinations; Extracellular Space; Intracranial Hypertension; Liver Failure, Acute; Ornithine; Phenylacetates; Swine

2009
Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis.
    Journal of hepatology, 2012, Volume: 56, Issue:1

    Topics: Amino Acids; Ammonia; Animals; Brain; Disease Models, Animal; Evoked Potentials, Motor; Glutamine; Hepatic Encephalopathy; Male; Ornithine; Phenylacetates; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley

2012
Ammonia reduction with ornithine phenylacetate restores brain eNOS activity via the DDAH-ADMA pathway in bile duct-ligated cirrhotic rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Amidohydrolases; Ammonia; Animals; Arginine; Bile Ducts; Brain; Ligation; Liver Cirrhosis; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Ornithine; Phenylacetates; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2012
Population Pharmacokinetic Analysis to Assist Dose Selection of the L-Ornithine Salt of Phenylacetic Acid.
    Clinical pharmacokinetics, 2022, Volume: 61, Issue:4

    Topics: Adult; Ammonia; Clinical Trials as Topic; Hepatic Encephalopathy; Humans; Ornithine; Phenylacetates

2022