ornithine has been researched along with ornithine phenylacetate in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (68.18) | 24.3611 |
| 2020's | 7 (31.82) | 2.80 |
| Authors | Studies |
|---|---|
| Arranz, JA; Córdoba, J; Oria, M; Raguer, N; Riudor, E; Romero-Giménez, J | 1 |
| Davies, NA; Jalan, R; Mookerjee, RP; Stadlbauer, V; Vairappan, B; Wright, G | 1 |
| Bak, LK; Dadsetan, S; Jalan, R; Keiding, S; Ott, P; Schousboe, A; Sørensen, M; Vilstrup, H; Waagepetersen, HS | 1 |
| Jalan, R; Jover-Cobos, M; Noiret, L; Sharifi, Y | 1 |
| Davies, N; Habtesion, A; Jalan, R; Jover-Cobos, M; Lee, K; Noiret, L; Romero-Gomez, M; Sharma, V | 1 |
| Fuskevåg, OM; Jalan, R; Kristiansen, RG; Mæhre, H; Revhaug, A; Rose, CF; Ytrebø, LM | 1 |
| Rahimi, RS; Rockey, DC | 1 |
| Sussman, NL | 1 |
| Cross, TJ; Ellul, MA; Gholkar, SA | 1 |
| Andreola, F; Balasubramaniyan, V; De Chiara, F; Jalan, R; Khetan, V; Malago, M; Mookerjee, RP; Pinzani, M; Rombouts, K | 1 |
| Kristiansen, RG; Rose, CF; Ytrebø, LM | 1 |
| Kristiansen, RG | 1 |
| Arias, N; Hadjihambi, A; Jalan, R; Sheikh, M | 1 |
| Bukofzer, S; Clasen, K; Durkalski, V; Fontana, RJ; Ganger, D; Gottfried, M; Hameed, B; Hanje, AJ; Koch, D; Lee, WM; Little, L; Ravis, WR; Sherker, A; Stravitz, RT; Subramanian, RM | 1 |
| Alsahhar, JS; Rahimi, RS | 1 |
| Alimirah, M; Gordon, SC; Sadiq, O | 1 |
| Bajaj, JS; Bhamidimarri, KR; Bukofzer, S; Potthoff, A; Pyrsopoulos, N; Rahimi, RS; Safadi, R; Thabut, D | 1 |
| Tapper, EB | 2 |
| Bémeur, C; Bosoi, CR; Clément, MA; Oliveira, MM; Rose, CF; Tremblay, M | 1 |
| Brown, KA; Brown, RS; Flamm, SL; Rahimi, RS | 1 |
| Bajaj, JS; Bukofzer, S; Devarakonda, KR; Jamil, K; Potthoff, A; Pyrsopoulos, N; Rahimi, RS; Ram Bhamidimarri, K; Safadi, R; Thabut, D; Wang, L | 1 |
10 review(s) available for ornithine and ornithine phenylacetate
| Article | Year |
|---|---|
Ornithine phenylacetate revisited.
Topics: Animals; Brain; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Liver Diseases; Liver Failure; Ornithine; Rats | 2013 |
Novel Ammonia-Lowering Agents for Hepatic Encephalopathy.
Topics: Ammonia; Carbon; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Ornithine; Oxides; Phenylbutyrates; Polyethylene Glycols; Urea | 2015 |
Treatment of Overt Hepatic Encephalopathy.
Topics: Amino Acids, Branched-Chain; Ammonia; Arteriovenous Fistula; Dipeptides; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Lactulose; Liver Failure; Malnutrition; Ornithine; Phenylbutyrates; Probiotics; Rifamycins; Rifaximin | 2015 |
Hepatic encephalopathy due to liver cirrhosis.
Topics: Albumins; Amino Acids; Diagnosis, Differential; Diet; Disaccharides; Drug Resistance; Electroencephalography; Glycerol; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Magnetic Resonance Imaging; Neomycin; Neurologic Examination; Nucleic Acid Synthesis Inhibitors; Ornithine; Phenylbutyrates; Probiotics; Protein Synthesis Inhibitors; Rifamycins; Rifaximin; Terminal Care; Tomography, X-Ray Computed | 2015 |
Glycine and hyperammonemia: potential target for the treatment of hepatic encephalopathy.
Topics: Animals; Drug Delivery Systems; Glycine; Hepatic Encephalopathy; Humans; Hyperammonemia; Ornithine; Treatment Outcome | 2016 |
Current state of knowledge of hepatic encephalopathy (part I): newer treatment strategies for hyperammonemia in liver failure.
Topics: Ammonia; Animals; Glutamate-Ammonia Ligase; Health Knowledge, Attitudes, Practice; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Failure; Ornithine; Treatment Outcome | 2016 |
Hepatic encephalopathy: a critical current review.
Topics: Albumins; Ammonia; Anti-Bacterial Agents; Bile Acids and Salts; Brain; Brain Edema; Cognitive Dysfunction; Dipeptides; Energy Metabolism; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Ornithine; Portasystemic Shunt, Surgical; Prognosis; Psychometrics; Severity of Illness Index; Synaptic Transmission | 2018 |
Updates on the pathophysiology and therapeutic targets for hepatic encephalopathy.
Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Frailty; Gastrointestinal Agents; Gastrointestinal Microbiome; Glycerol; Hepatic Encephalopathy; Humans; Hypertension, Portal; Lactulose; Liver Cirrhosis; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Rifaximin; Trace Elements; Zinc | 2019 |
Novel Therapies in Hepatic Encephalopathy.
Topics: Acetylcarnitine; Albumins; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Flumazenil; GABA Modulators; Glycerol; Hepatic Encephalopathy; Humans; Nootropic Agents; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Surface-Active Agents | 2020 |
Overt Hepatic Encephalopathy: Current Pharmacologic Treatments and Improving Clinical Outcomes.
Topics: Gastrointestinal Agents; Hepatic Encephalopathy; Hospitalization; Humans; Lactulose; Length of Stay; Mortality; Ornithine; Rifaximin; Secondary Prevention | 2021 |
2 trial(s) available for ornithine and ornithine phenylacetate
| Article | Year |
|---|---|
Efficacy and Safety of Ornithine Phenylacetate for Treating Overt Hepatic Encephalopathy in a Randomized Trial.
Topics: Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Ornithine; Treatment Outcome | 2021 |
Pharmacokinetics/pharmacodynamics of L-ornithine phenylacetate in overt hepatic encephalopathy and the effect of plasma ammonia concentration reduction on clinical outcomes.
Topics: Adult; Ammonia; Hepatic Encephalopathy; Humans; Ornithine; Phenylacetates | 2022 |
10 other study(ies) available for ornithine and ornithine phenylacetate
| Article | Year |
|---|---|
Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis.
Topics: Amino Acids; Ammonia; Animals; Brain; Disease Models, Animal; Evoked Potentials, Motor; Glutamine; Hepatic Encephalopathy; Male; Ornithine; Phenylacetates; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley | 2012 |
Reduction in hyperammonaemia by ornithine phenylacetate prevents lipopolysaccharide-induced brain edema and coma in cirrhotic rats.
Topics: Animals; Antibodies, Monoclonal; Bile Ducts; Blotting, Western; Body Water; Brain; Brain Edema; Cytokines; Hyperammonemia; Infliximab; Injections, Intraperitoneal; Interleukin-6; Ligation; Lipopolysaccharides; Liver Cirrhosis; Ornithine; Rats; Tumor Necrosis Factor-alpha | 2012 |
Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia.
Topics: Acetates; Ammonia; Animals; Arteries; Bile Ducts; Drug Interactions; Female; Glutamine; Hyperammonemia; Kidney; Ligation; Liver; Liver Cirrhosis, Biliary; Muscle, Skeletal; Nitrogen Isotopes; Ornithine; Phenols; Rats; Rats, Wistar; Tissue Distribution | 2013 |
Ornithine phenylacetate targets alterations in the expression and activity of glutamine synthase and glutaminase to reduce ammonia levels in bile duct ligated rats.
Topics: Ammonia; Animals; Bile Ducts; Disease Models, Animal; End Stage Liver Disease; Glutamate-Ammonia Ligase; Glutaminase; Ligation; Liver; Male; Ornithine; Rats; Rats, Sprague-Dawley | 2014 |
L-Ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway.
Topics: Ammonia; Animals; Biomarkers; Brain; Disease Models, Animal; Female; Glycine; Hyperammonemia; Kidney; Liver Failure, Acute; Ornithine; Random Allocation; Swine; Time Factors | 2014 |
Ammonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension.
Topics: Ammonia; Animals; Cell Proliferation; Cells, Cultured; Endoplasmic Reticulum; Hepatic Stellate Cells; Humans; Hypertension, Portal; Male; Ornithine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2016 |
Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia.
Topics: Acetates; Adolescent; Adult; Aged; Ammonia; Female; Glutamine; Humans; Hyperammonemia; Kidney Function Tests; Liver; Liver Failure, Acute; Male; Middle Aged; Ornithine; Phenols; Registries; Treatment Outcome; Young Adult | 2018 |
A Trial of Ornithine Phenylacetate and the Arc of Ammonia's History in the Management of Overt Hepatic Encephalopathy.
Topics: Ammonia; Hepatic Encephalopathy; Humans; Ornithine | 2021 |
Bile-duct ligation renders the brain susceptible to hypotension-induced neuronal degeneration: Implications of ammonia.
Topics: Ammonia; Animals; Antigens, Nuclear; Anxiety; Apoptosis; Behavior, Animal; Bile Ducts; Caspase 3; Cerebrovascular Circulation; Disease Models, Animal; Hepatic Encephalopathy; Hyperammonemia; Hypotension; Ligation; Male; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Ornithine; Rats; Rats, Sprague-Dawley | 2021 |
Reply.
Topics: Ammonia; Hepatic Encephalopathy; Humans; Ornithine | 2021 |