ornithine and mitoguazone

ornithine has been researched along with mitoguazone in 94 studies

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-199094 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexandre, H1
Linebaugh, BE; Mulder, JA; Rillema, JA1
Scamans, E; Tyms, AS; Williamson, JD1
Emanuelsson, H; Heby, O1
Brawley, JV; Ferro, AJ1
Hölttä, E; Hovi, T; Jänne, J1
Morris, DR; Seyfried, CE1
Alhonen-Hongisto, L; Jänne, J; Kallio, A; Pösö, H1
Brinkley, BR; Nishioka, K; Rao, PN; Sunkara, PS1
Andersson, G; Gray, JW; Heby, O1
Paul, D; Rupniak, HT1
Knutson, JC; Morris, DR1
Hölttä, E; Jänne, J; Pohjanpelto, P1
Abdel-Monem, MM; Newton, NE1
Jorstad, CM; Morris, DR; Seyfried, CE1
Adachi, K; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M1
Keir, HM; Wallace, HM1
Dunzendorfer, U; Knöner, M1
Endoh, F; Fujimoto, S; Igarashi, K; Kawata, S; Miyazaki, M; Ohta, M; Shimura, T; Shrestha, RD; Sugasawa, H; Takahashi, O3
Endoh, F; Fujimoto, S; Igarashi, K; Miyazaki, M; Ohta, M; Okui, K; Shrestha, RD; Togawa, Y1
Levin, VA1
Hidaka, H; Kawakami, K; Ohmura, T; Onoue, K; Yamamoto, Y1
Członkowska, M; Guszkiewicz, A; Zwierzchowski, L1
Ask, A; Heby, O; Oredsson, SM; Persson, L1
Kingsnorth, AN1
Romijn, JC; Splinter, TA1
Seidenfeld, J; Williams-Ashman, HG1
Ajani, JA; Grossie, VB; Nishioka, K; Ota, DM; Stephens, LC1
Alhonen-Hongisto, L; Levin, VA; Marton, LJ1
Jänne, J; Käpyaho, K; Sinervirta, R1
Kramer, DL; Paul, B; Porter, CW1
Fujimoto, S; Igarashi, K; Miyazaki, M; Okui, K; Shrestha, RD1
Franzen, MA; Mitchell, JL; Qasba, P; Stofko, RE1
Manni, A; Pontari, M; Wright, C1
Pegg, AE; Shirahata, A1
Lawson, DE; Steeves, RM1
Deen, DF; Feuerstein, BG; Marton, LJ1
Lawson, DM; Ofenstein, JP; Rillema, JA1
Jenkins, JJ; Klein, J; McCullough, JL; Peckham, P; Weinstein, GD1
Dunzendorfer, U1
Landahl, HD; Levin, VA1
Heby, O; Linden, M; Oredsson, SM1
Jänne, J; Käpyaho, K; Kousa, M; Lauharanta, J; Linnamaa, K; Mustakallio, K1
Jänne, J; Käpyaho, K; Kariniemi, AL; Virtanen, I1
Burchenal, JH; Warrell, RP1
Tyms, AS; Williamson, JD1
Gordon, AM; Keir, HM; Pearson, CK; Wallace, HM1
Alhonen-Hongisto, L; Jänne, J; Kallio, A; Seppänen, P1
Balis, ME; Dunzendorfer, U; Kleinert, E; Relyea, NM; Whitmore, WF1
Alhonen-Hongisto, L; Jänne, J; Seppänen, P4
Friend, DS; Marton, LJ; Oredsson, SM1
Chang, CC; Prakash, NJ; Sjoerdsma, A; Sunkara, PS1
Laitinen, SI; Pajunen, AE1
Jänne, J; Käpyaho, K1
Dunzendorfer, U; Kleinert, E; Whitmore, WF1
Jänne, J; Käpyaho, K; Lauharanta, J2
Hietala, OA; Laitinen, PH; Lapinjoki, SP; Pajunen, AE; Pulkka, AE1
Jänne, J; Kallio, A1
Burchenal, JH; Coonley, CJ; Warrell, RP1
Jenkins, JJ; McCullough, JL; Rosenblum, MG; Weinstein, GD1
Endoh, F; Fujimoto, S; Igarashi, K; Miyazaki, M; Ohyama, Y; Okui, K; Shimura, T; Shrestha, RD; Sugasawa, H; Takahashi, O1
Kramer, DL; Porter, CW; Wiseman, A; Zychlinski, L1
Herr, HW; Kleinert, EL; Relyea, NM; Whitmore, WF1
Covey, DF; Fair, WR; Heston, WD; Kadmon, D1
Balis, ME; Dunzendorfer, U; Fogh, J; Releyea, N; Whitmore, WF1
Jänne, J; Kallio, A; Nikula, P1
Herr, HW; Kleinert, EL1
Jänne, J; Kallio, A; Käpyaho, K1
Alhonen-Hongisto, L; Elo, H; Fagerström, R; Jänne, J; Laine, R1
Burchenal, JH; Conti, PS; Herr, HW; Kleinert, EL; Whitmore, WF1
Alhonen-Hongisto, L; Elo, H; Fagerström, R; Jänne, J; Lumme, P; Seppänen, P1
Marton, LJ; Oredsson, SM1
Igarashi, K; Morris, DR1
Borcich, JK; Byrd, D; Campbell, J; Davis, RL; Levin, VA1
Gutin, PH; Wilson, CB1
Campione, AL; Van Winkle, LJ2
Deen, DF; Marton, LJ; Seidenfeld, J1
Fozard, JR; Grove, J; Prakash, NJ1
Alhonen-Hongisto, L; Jänne, J; Seppänen, P; Siimes, M2
Erwin, BG; Florini, JR; Pegg, AE; Richman, RA; Stoscheck, CM1
Jänne, J; Käpyaho, K; Linnamaa, K1
Seppänen, P1
Fuller, DJ; Gerner, EW1
Fujimoto, S; Hirose, S; Igarashi, K; Okui, K; Shrestha, RD; Terao, K1
Bellett, AJ; Cheetham, BF1
Grove, J; Koch-Weser, J; Mamont, PS; Prakash, NJ; Schechter, PJ; Sjoerdsma, A1

Reviews

5 review(s) available for ornithine and mitoguazone

ArticleYear
Chemotherapy of primary brain tumors.
    Neurologic clinics, 1985, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Brain Stem; Child; Eflornithine; Ependymoma; Fluorouracil; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methotrexate; Mitoguazone; Mitolactol; Neoplasm Recurrence, Local; Ornithine; Prednisone; Risk; Thioguanine; Vincristine

1985
The chemotherapeutic potential of polyamine antimetabolites.
    Annals of the Royal College of Surgeons of England, 1986, Volume: 68, Issue:2

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Body Weight; Cell Division; Cell Line; Child; Drug Interactions; Eflornithine; Female; Humans; Mice; Mitoguazone; Neoplasms; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats

1986
Aspects of the biochemical pharmacology of methyl glyoxal bis(guanylhydrazone).
    Biochemical pharmacology, 1986, Apr-15, Volume: 35, Issue:8

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Carnitine; Cell Division; DNA Replication; Eflornithine; Energy Metabolism; Humans; Kinetics; Leukemia; Male; Mitochondria; Mitoguazone; Nucleic Acids; Ornithine; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Polyamines; Protein Biosynthesis; Putrescine; Virus Replication

1986
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship

1983
Use of polyamine antimetabolites in experimental tumours and in human leukemia.
    Medical biology, 1981, Volume: 59, Issue:5-6

    Topics: Animals; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Humans; Leukemia; Mitoguazone; Neoplasms, Experimental; Ornithine; Polyamines

1981

Trials

1 trial(s) available for ornithine and mitoguazone

ArticleYear
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship

1983

Other Studies

89 other study(ies) available for ornithine and mitoguazone

ArticleYear
[Effect of inhibitors of polyamine biosynthesis on primary differentiation of mouse egg].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1978, Apr-24, Volume: 286, Issue:16

    Topics: Animals; Cell Differentiation; Cells, Cultured; Female; Fertilization; Guanidines; Mice; Mitoguazone; Ornithine; Ovum; Putrescine

1978
Regulation of casein synthesis by polyamines in mammary gland explants of mice.
    Endocrinology, 1977, Volume: 100, Issue:2

    Topics: Animals; Arginine; Caseins; Cyclic AMP; Cyclic GMP; Female; Hydrocortisone; In Vitro Techniques; Insulin; Mammary Glands, Animal; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Phospholipases; Polyamines; Prolactin; Prostaglandins F; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Transcription, Genetic

1977
Polyamine metabolism in MRC5 cells infected with different herpesviruses.
    Biochemical and biophysical research communications, 1979, Jan-30, Volume: 86, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Carboxy-Lyases; Cell Line; Cell Transformation, Viral; Cytomegalovirus; Fibroblasts; Herpesviridae; Humans; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Virus Replication

1979
Inhibition of putrescine synthesis blocks development of the polychete Ophryotrocha labronica at gastrulation.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:2

    Topics: Animals; Embryo, Nonmammalian; Female; Mitoguazone; Ornithine; Polychaeta; Putrescine; Spermine; Time Factors; Zygote

1978
Polyamine biosynthesis during germination of yeast ascospores.
    Journal of bacteriology, 1979, Volume: 140, Issue:2

    Topics: Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Saccharomyces cerevisiae; Spores, Fungal

1979
Suppression of the formation of polyamines and macromolecules by DL-alpha-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) in phytohaemagglutinin-activated human lymphocytes.
    The Biochemical journal, 1979, Jan-15, Volume: 178, Issue:1

    Topics: Blood Proteins; DNA; Dose-Response Relationship, Drug; Guanidines; Lymphocyte Activation; Lymphocytes; Macromolecular Substances; Mitoguazone; Ornithine; Phytohemagglutinins; Polyamines; RNA

1979
Relationship between inhibition of polyamine biosynthesis and DNA replication in activated lymphocytes.
    Cancer research, 1979, Volume: 39, Issue:12

    Topics: Animals; Cattle; Cell Division; DNA Replication; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mitoguazone; Ornithine; Polyamines; Thymine Nucleotides

1979
Effect of inhibitors on ornithine and adenosylmethionine decarboxylases on the synthesis of deoxyribonucleic acid in Ehrlich ascites cells in vivo.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1979, Volume: 33, Issue:8

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Diamines; DNA, Neoplasm; Female; Guanidines; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine; Time Factors

1979
Role of polyamines in cytokinesis of mammalian cells.
    Experimental cell research, 1979, Mar-01, Volume: 119, Issue:1

    Topics: Cell Division; Cell Line; Cytoskeleton; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine

1979
Interference with S and G2 phase progression by polyamine synthesis inhibitors.
    Experimental cell research, 1978, Volume: 111, Issue:2

    Topics: Cell Cycle; Cell Line; DNA; Guanidines; Interphase; Mitoguazone; Ornithine

1978
Lack of a correlation between polyamine synthesis and DNA synthesis by cultured rat liver cells and fibroblasts.
    Journal of cellular physiology, 1978, Volume: 96, Issue:2

    Topics: Blood; Cell Cycle; Cells, Cultured; DNA; Interphase; Kinetics; Mitoguazone; Ornithine; Polyamines

1978
Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei.
    Biochimica et biophysica acta, 1978, Sep-27, Volume: 520, Issue:2

    Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Replication; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine

1978
Dissociation of the early antiproliferative action of methylglyoxal bis(guanylhydrazone) from polyamine depletion. A comparison of the effects of DL-alpha-difluromethyl ormithine and methylglyoxal bis(guanylhydrazone) on the growth of human fibroblasts.
    FEBS letters, 1979, Jan-01, Volume: 97, Issue:1

    Topics: Cell Division; Cells, Cultured; DNA; Fibroblasts; Guanidines; Humans; Mitoguazone; Ornithine; Polyamines; Thymidine Kinase

1979
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine

1977
Inhibition of the synthesis of polyamines and DNA in activated lymphocytes by a combination of alpha-methylornithine and methylglyoxal bis(guanylhydrazone).
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: Animals; Cattle; Cell Division; Concanavalin A; DNA; DNA Replication; Drug Interactions; Guanidines; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mitoguazone; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; RNA; Spermidine; Spermine

1977
Effect of DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase, on polyamine metabolism in isoproterenol-stimulated mouse parotid glands.
    Journal of biochemistry, 1975, Volume: 77, Issue:4

    Topics: Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Carboxy-Lyases; DNA; Hydrazines; In Vitro Techniques; Isoproterenol; Male; Mice; Mitoguazone; Mitosis; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Parotid Gland; Polyamines; Putrescine; RNA; Spermidine; Spermine; Stimulation, Chemical; Valine

1975
Factors affecting polyamine excretion from mammalian cells in culture. Inhibitors of polyamine biosynthesis.
    FEBS letters, 1986, Jan-01, Volume: 194, Issue:1

    Topics: Acetylation; Animals; Canavanine; Cell Line; Cricetinae; DNA; Kidney; Mitoguazone; Ornithine; Polyamines; Proteins; Pyruvaldehyde; RNA

1986
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study].
    Onkologie, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carboxy-Lyases; Carcinoma; Eflornithine; Estrogens; Humans; Male; Mitoguazone; Neoplasm Metastasis; Ornithine; Ornithine Decarboxylase Inhibitors; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatitis; Putrescine; Rats; Spermidine; Spermine

1985
[Anticancer treatment with a combination of antimetabolites of polyamine and pyrimidine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10

    Topics: Animals; DNA Replication; Drug Therapy, Combination; Eflornithine; Floxuridine; Fluorouracil; Mice; Mice, Nude; Mitoguazone; Ornithine; Polyamines; Spermine; Stomach Neoplasms

1985
Combined therapy of polyamine antimetabolites and antitumor drugs for human gastric cancer xenotransplanted into nude mice.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma; Eflornithine; Floxuridine; Fluorouracil; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoguazone; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Ornithine; Stomach Neoplasms

1986
Induction and regulation of human interleukin 2 gene expression: significance of protein kinase C activation.
    Journal of biochemistry, 1986, Volume: 100, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Enzyme Activation; Gene Expression Regulation; Humans; Interleukin-2; Isoquinolines; Lymphocytes; Mitoguazone; Ornithine; Phytohemagglutinins; Piperazines; Prostaglandins E; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine

1986
[Studies on hyperthermia by the use of a thermosensitizing drug].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; DNA Replication; Eflornithine; Humans; Hyperthermia, Induced; Mice; Mice, Inbred BALB C; Mitoguazone; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Ornithine; Stomach Neoplasms

1986
Effect of polyamine limitation on DNA synthesis and development of mouse preimplantation embryos in vitro.
    Journal of reproduction and fertility, 1986, Volume: 76, Issue:1

    Topics: Animals; Blastocyst; Culture Media; DNA; Eflornithine; Embryonic Development; Female; In Vitro Techniques; Mice; Mitoguazone; Ornithine; Polyamines; Pregnancy; Spermine

1986
Synergistic antileukemic effect of two polyamine synthesis inhibitors. Host survival and cell-cycle kinetic analysis.
    International journal of cancer, 1986, Mar-15, Volume: 37, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Cycle; Drug Synergism; Eflornithine; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines

1986
Phase I study of alpha-difluoromethylornithine and methyl-GAG.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Deafness; Drug Evaluation; Eflornithine; Humans; Leukopenia; Middle Aged; Mitoguazone; Neoplasms; Ornithine; Thrombocytopenia

1986
Red blood cell polyamine levels and host toxicity during continuous alpha-difluoromethylornithine infusion.
    International journal of cancer, 1986, Aug-15, Volume: 38, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Eflornithine; Erythrocytes; Intestinal Mucosa; Male; Mitoguazone; Neoplasms, Experimental; Ornithine; Platelet Count; Polyamines; Rats; Rats, Inbred F344

1986
Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone).
    Cancer research, 1985, Volume: 45, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Eflornithine; Guanidines; Kinetics; Mitochondria; Mitoguazone; Ornithine; Putrescine; Pyruvates; Pyruvic Acid; Rats; Spermidine; Temperature; Time Factors

1985
Effects of inhibitors of polyamine biosynthesis on the growth and melanogenesis of murine melanoma cells.
    Cancer research, 1985, Volume: 45, Issue:4

    Topics: Animals; Cell Division; Cells, Cultured; Eflornithine; Guanidines; Melanins; Melanoma; Mice; Mitoguazone; Monophenol Monooxygenase; Ornithine; Polyamines

1985
Effect of pretreatment with alpha-difluoromethylornithine on the selectivity of methylglyoxal bis(guanylhydrazone) for tumor tissue in L1210 leukemic mice.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Animals; Carbon Radioisotopes; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mice, Inbred DBA; Mitoguazone; Ornithine

1985
Antitumor effects of two polyamine antimetabolites combined with mitomycin C on human stomach cancer cells xenotransplanted into nude mice.
    International journal of cancer, 1985, Jun-15, Volume: 35, Issue:6

    Topics: Adenocarcinoma, Papillary; Animals; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; DNA; Eflornithine; Humans; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoguazone; Mitomycin; Mitomycins; Ornithine; Polyamines; Stomach Neoplasms

1985
Ornithine decarboxylase modification and polyamine-stimulated enzyme inactivation in HTC cells.
    The Biochemical journal, 1985, Jun-01, Volume: 228, Issue:2

    Topics: Animals; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Cycloheximide; Eflornithine; Isoenzymes; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Spermidine

1985
Polyamines and estrogen control of growth of the NMU-induced rat mammary tumor.
    Breast cancer research and treatment, 1985, Volume: 5, Issue:2

    Topics: Animals; Body Weight; Cell Division; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitoguazone; Nitrosourea Compounds; Ornithine; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen

1985
Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate.
    The Journal of biological chemistry, 1985, Aug-15, Volume: 260, Issue:17

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cycloheximide; Eflornithine; Half-Life; Immunosorbent Techniques; Kinetics; Liver; Male; Mitoguazone; Molecular Weight; Ornithine; Prostate; Putrescine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Spermidine; Spermine

1985
Effect of 1,25-dihydroxyvitamin D on S-adenosylmethionine decarboxylase in chick intestine.
    Biochimica et biophysica acta, 1985, Sep-06, Volume: 841, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Calcitriol; Calcium; Carboxy-Lyases; Chickens; Dactinomycin; Dose-Response Relationship, Drug; Duodenum; Eflornithine; Enzyme Induction; Intestinal Absorption; Intestinal Mucosa; Kinetics; Mitoguazone; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Spermine; Steroids

1985
Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Animals; Brain Neoplasms; Carmustine; Cell Cycle; Cell Survival; Cyclohexylamines; Eflornithine; Mitoguazone; Ornithine; Polyamines; Putrescine; Rats; Spermidine Synthase; Transferases

1985
Prolactin stimulation of Nb 2 node lymphoma cell division is inhibited by polyamine biosynthesis inhibitors.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cell Line; Drug Interactions; Eflornithine; Lymphoma; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Prolactin; Rats

1985
Regulation of epidermal proliferation in mouse epidermis by combination of difluoromethyl ornithine (DFMO) and methylglyoxal bis(guanylhydrazone) (MGBG).
    The Journal of investigative dermatology, 1985, Volume: 85, Issue:6

    Topics: Animals; DNA; Drug Combinations; Eflornithine; Epidermis; Growth; Mice; Mitoguazone; Ornithine; Polyamines; Skin

1985
[Polyamines, polyamine antimetabolites and urogenital tumors. State of research and clinical results].
    Urologia internationalis, 1985, Volume: 40, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Antimetabolites, Antineoplastic; Carboxy-Lyases; Drug Combinations; Eflornithine; Enzyme Induction; Enzyme Inhibitors; Humans; Kidney Neoplasms; Male; Mitoguazone; Ornithine; Polyamines; Prostatic Neoplasms; Urogenital Neoplasms

1985
Pharmacokinetic approaches to drug distribution in the cerebrospinal fluid based on ventricular administration in beagle dogs.
    Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:4

    Topics: Animals; Brain Chemistry; Dogs; Eflornithine; Half-Life; Injections, Intraventricular; Inulin; Kinetics; Male; Mitoguazone; Models, Biological; Nimustine; Nitrosourea Compounds; Ornithine; Pharmaceutical Preparations

1985
Increased rate of tumor cell death caused by polyamine synthesis inhibitors.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1984, Volume: 47, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Division; Cell Survival; Eflornithine; Guanidines; Male; Mice; Mice, Inbred Strains; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines

1984
Methylglyoxal BIS (guanylhydrazone) and alpha-difluoromethylornithine-induced polyamine deprivation in psoriatic lesions.
    Acta dermato-venereologica, 1982, Volume: 62, Issue:3

    Topics: Carboxy-Lyases; Dose-Response Relationship, Drug; Eflornithine; Guanidines; Humans; Injections, Intradermal; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Psoriasis; Putrescine; Skin; Spermidine; Spermine

1982
Effect of polyamine antimetabolites on cultured human keratinocytes from normal and uninvolved psoriatic skin.
    The British journal of dermatology, 1984, Volume: 111, Issue:4

    Topics: Antimetabolites; Cell Division; Cells, Cultured; DNA; Eflornithine; Guanidines; Humans; Keratins; Mitoguazone; Ornithine; Protein Biosynthesis; Psoriasis; Putrescine; Skin; Spermidine; Spermine

1984
Inhibitors of polyamine biosynthesis block human cytomegalovirus replication.
    Nature, 1982, Jun-24, Volume: 297, Issue:5868

    Topics: Antiviral Agents; Cells, Cultured; Cytomegalovirus; Eflornithine; Guanidines; Humans; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine; Virus Replication

1982
Activation of ADP-ribosyltransferase in polyamine-depleted mammalian cells.
    The Biochemical journal, 1984, Apr-01, Volume: 219, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Centrifugation, Density Gradient; Chromatography; Cricetinae; DNA; Enzyme Activation; Fibroblasts; Kidney; Mitoguazone; Nucleotidyltransferases; Ornithine; Poly(ADP-ribose) Polymerases; Spermidine; Spermine

1984
Modulation of the tissue disposition of methylglyoxal bis(guanylhydrazone) in mice by polyamine depletion and by polyamine administration.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Animals; Bone Marrow; Carboxy-Lyases; Eflornithine; Guanidines; Intestine, Small; Liver; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Tissue Distribution

1983
Antigrowth effect of some inhibitors of polyamine synthesis on transplantable prostate cancer.
    Oncology, 1983, Volume: 40, Issue:1

    Topics: Animals; Body Weight; Drug Therapy, Combination; Eflornithine; Guanidines; Male; Mitoguazone; Neoplasm Transplantation; Neoplasms, Experimental; Ornithine; Polyamines; Prostatic Neoplasms; Rats; Vidarabine

1983
Combined use of 2-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) in normal and leukemia-bearing mice.
    Cancer letters, 1983, Volume: 18, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mice, Inbred DBA; Mitoguazone; Ornithine; Spleen; Time Factors; Tissue Distribution

1983
Changes in mitochondrial structure and function in 9l rat brain tumor cells treated in vitro with alpha-difluoromethylornithine, a polyamine biosynthesis inhibitor.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:3

    Topics: Animals; Brain; Cells, Cultured; Eflornithine; Microscopy, Electron; Mitochondria; Mitoguazone; Ornithine; Polyamines; Pyruvates; Pyruvic Acid; Rats

1983
Cytotoxicity of methylglyoxal bis(guanylhydrazone) in combination with alpha-difluoromethylornithine against HeLa cells and mouse L1210 leukemia.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Guanidines; HeLa Cells; Humans; Leukemia L1210; Mice; Mice, Inbred Strains; Mitoguazone; Neoplasm Transplantation; Ornithine; Polyamines

1983
Inhibition of polyamine synthesis blocks urinary secretion of beta-glucuronidase from mouse kidney.
    Biochemical and biophysical research communications, 1983, Apr-29, Volume: 112, Issue:2

    Topics: Animals; Eflornithine; Enzyme Induction; Glucuronidase; Kidney; Male; Mice; Mitoguazone; Ornithine; Polyamines; Testosterone

1983
Stimulation of melanotic expression in murine melanoma cells exposed to polyamine antimetabolites.
    Biochemical and biophysical research communications, 1983, May-31, Volume: 113, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Drug Synergism; Eflornithine; Guanidines; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Mitoguazone; Monophenol Monooxygenase; Ornithine; Polyamines

1983
Experimental chemotherapy in a transplantable renal adenocarcinoma. I: Effects of some inhibitors of polyamine synthesis.
    Urologia internationalis, 1983, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Animals; Eflornithine; Guanidines; Kidney; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Mitoguazone; Neoplasms, Experimental; Ornithine; Polyamines

1983
Inhibition of DNA and protein synthesis in UV-irradiated mouse skin by 2-difluoromethylornithine, methylglyoxal bis(guanylhydrazone), and their combination.
    The Journal of investigative dermatology, 1983, Volume: 81, Issue:2

    Topics: Animals; DNA Replication; Drug Interactions; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Protein Biosynthesis; Putrescine; Skin; Spermidine; Ultraviolet Rays

1983
Metabolic consequences of inhibition of cerebral adenosylmethionine decarboxylase by methylglyoxal bis(Guanylhydrazone).
    Journal of neurochemistry, 1983, Volume: 41, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Brain; Carboxy-Lyases; Eflornithine; Guanidines; Injections, Intraventricular; Male; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines

1983
Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites.
    The Biochemical journal, 1983, Jun-15, Volume: 212, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agents; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mice, Inbred DBA; Mitoguazone; Ornithine; Polyamines

1983
Sequential inhibition of polyamine synthesis. A phase I trial of DFMO (alpha-difluoromethylornithine) and methyl-GAG [methylglyoxal-bis(guanylhydrazone)].
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Drug Therapy, Combination; Eflornithine; Guanidines; Humans; Middle Aged; Mitoguazone; Neoplasms; Ornithine; Polyamines

1983
Percutaneous penetration of methylglyoxal bis(guanylhydrazone): effects on hairless mouse epidermis in vivo.
    The Journal of investigative dermatology, 1983, Volume: 81, Issue:5

    Topics: Administration, Topical; Animals; DNA; Eflornithine; Guanidines; In Vitro Techniques; Mice; Mice, Hairless; Mitoguazone; Ornithine; Polyamines; Psoriasis; Skin; Skin Absorption

1983
[Combined antitumor therapy with polyamine biosynthesis inhibitors and mitomycin C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Eflornithine; Humans; Mice; Mice, Nude; Mitoguazone; Mitomycin; Mitomycins; Neoplasm Transplantation; Ornithine; Stomach Neoplasms

1983
Biochemical and ultrastructural characterization of human cell variants resistant to the antiproliferative effects of methylglyoxal bis(guanylhydrazone).
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Adenosylmethionine Decarboxylase; Cell Cycle; Cell Line; Drug Resistance; Eflornithine; Genetic Variation; Guanidines; Humans; Kinetics; Lung; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Oxygen Consumption; Pyruvates; Pyruvic Acid

1983
Potentiation of methylglyoxal-bis-guanylhydrazone by alpha-difluoromethylornithine in rat prostate cancer.
    Cancer, 1984, Mar-15, Volume: 53, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line; Drug Synergism; Eflornithine; Guanidines; Humans; Male; Mitoguazone; Neoplasm Transplantation; Ornithine; Prostatic Neoplasms; Rats; Rats, Inbred Strains

1984
Differential effect of alpha-difluoromethylornithine on the in vivo uptake of 14C-labeled polyamines and methylglyoxal bis(guanylhydrazone) by a rat prostate-derived tumor.
    Cancer research, 1984, Volume: 44, Issue:3

    Topics: Animals; Antineoplastic Agents; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Eflornithine; Guanidines; Male; Mitoguazone; Ornithine; Polyamines; Prostatic Neoplasms; Putrescine; Rats; Rats, Inbred Strains; Spermidine

1984
Some effects of inhibitors of polyamine synthesis on experimental prostatic cancer.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:1

    Topics: Adenine; Adenocarcinoma; Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Guanidines; Male; Mice; Mice, Nude; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Prostatic Neoplasms; Rats; Vidarabine

1984
Transfer of intestine-derived diamines into tumour cells during treatment of Ehrlich-ascites--carcinoma-bearing mice with polyamine anti-metabolites.
    The Biochemical journal, 1984, Mar-01, Volume: 218, Issue:2

    Topics: Animals; Cadaverine; Carcinoma, Ehrlich Tumor; Diamines; Eflornithine; Guanidines; Mice; Mitoguazone; Ornithine; Putrescine

1984
[Combined therapy with polyamine biosynthesis inhibitors and mitomycin C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:6

    Topics: Animals; DNA Replication; DNA, Neoplasm; Drug Therapy, Combination; Eflornithine; Guanidines; Humans; Mice; Mice, Nude; Mitoguazone; Mitomycin; Mitomycins; Neoplasm Transplantation; Ornithine; Stomach Neoplasms

1984
Antigrowth effect of polyamine biosynthesis inhibitors on the Dunning R 3327-G prostatic tumor.
    The Prostate, 1984, Volume: 5, Issue:4

    Topics: Adenocarcinoma; Animals; Body Weight; Cell Division; Drug Therapy, Combination; Eflornithine; Guanidines; Male; Mitoguazone; Ornithine; Polyamines; Prostatic Neoplasms; Rats; Rats, Inbred Strains

1984
Differential effects of 2-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) on the testosterone-induced growth of ventral prostate and seminal vesicles of castrated rats.
    The Biochemical journal, 1984, May-01, Volume: 219, Issue:3

    Topics: Animals; Castration; Eflornithine; Guanidines; Male; Mitoguazone; Ornithine; Polyamines; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles; Testosterone

1984
Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).
    The Biochemical journal, 1984, Jul-01, Volume: 221, Issue:1

    Topics: Animals; Cells, Cultured; Eflornithine; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Spermidine; Time Factors

1984
Effects of alpha-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) on the growth of experimental renal adenocarcinoma in mice.
    Cancer research, 1984, Volume: 44, Issue:10

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Cell Division; Drug Synergism; Eflornithine; Guanidines; Kidney Neoplasms; Male; Mice; Mice, Inbred BALB C; Mitoguazone; Neoplasm Metastasis; Ornithine; Tissue Distribution

1984
Glyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in tumour cells.
    The Biochemical journal, 1984, Jul-15, Volume: 221, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mitoguazone; Neoplasm Proteins; Ornithine; Polyamines

1984
Potential uses of polyamine biosynthesis inhibitors in tumor therapy.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Antineoplastic Agents; Cell Cycle; DNA Repair; Drug Therapy, Combination; Eflornithine; Humans; Mitoguazone; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Sister Chromatid Exchange

1984
Physiological effects in bovine lymphocytes of inhibiting polyamine synthesis with ethylglyoxal bis(guanylhydrazone).
    Cancer research, 1984, Volume: 44, Issue:11

    Topics: Animals; Aphidicolin; Cattle; Cycloheximide; Diterpenes; DNA Replication; Eflornithine; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Protein Biosynthesis; Proteins; Spermidine

1984
CNS toxicity and CSF pharmacokinetics of intraventricular DFMO and MGBG in beagle dogs.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Cerebral Ventricles; Dogs; Eflornithine; Guanidines; Injections, Intraventricular; Male; Metabolic Clearance Rate; Mitoguazone; Ornithine

1984
New therapeutic approaches for brain tumors.
    Cancer, 1984, Dec-01, Volume: 54, Issue:11 Suppl

    Topics: Brachytherapy; Brain Neoplasms; Bromodeoxyuridine; Eflornithine; Humans; Hyperthermia, Induced; Iodine Radioisotopes; Mitoguazone; Ornithine; Polyamines

1984
Periimplantation-like growth and development of mouse blastocysts in medium containing horse serum.
    Experientia, 1984, Sep-15, Volume: 40, Issue:9

    Topics: Animals; Blastocyst; Blood; Cattle; Culture Media; Embryo Implantation; Female; Fetal Blood; Horses; Mice; Mice, Inbred ICR; Mitoguazone; Ornithine; Polyamines; Spermidine; Spermine

1984
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1980, Volume: 38, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines; Putrescine; Radiation Tolerance; Rats; Spermidine; Spermine; X-Rays

1980
Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.
    Life sciences, 1980, Dec-08, Volume: 27, Issue:23

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Eflornithine; Estrus; Female; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Ovulation; Pregnancy; Putrescine; Rats; Spermidine; Spermine

1980
Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).
    The Biochemical journal, 1980, Dec-15, Volume: 192, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Mitoguazone; Ornithine; Ornithine Decarboxylase; Putrescine; Spermidine

1980
Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells.
    Biochimica et biophysica acta, 1981, May-05, Volume: 674, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Eflornithine; Female; Guanidines; Humans; Iodoacetates; Iodoacetic Acid; Leukemia, Lymphoid; Mice; Mitoguazone; Ornithine; Putrescine; Spermine

1981
Death of tumor cells in response to the use of a system of stimulated polyamine uptake from the transport of methylglyoxal bis(guanylhydrazone).
    European journal of biochemistry, 1981, Sep-01, Volume: 118, Issue:3

    Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Survival; Cells, Cultured; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines

1981
Synergistic action of two polyamine antimetabolites leads to a rapid therapeutic response in childhood leukemia.
    International journal of cancer, 1981, Nov-15, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Child; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mitoguazone; Ornithine

1981
Effects of inhibitors of ornithine and S-adenosylmethionine decarboxylases on L6 myoblast proliferation.
    Journal of cellular physiology, 1982, Volume: 110, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Cells, Cultured; Eflornithine; Mitoguazone; Muscles; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine

1982
Effect of epidermal polyamine depletion on the accumulation of methylglyoxal bis(guanylhydrazone) in mouse skin.
    The Journal of investigative dermatology, 1982, Volume: 78, Issue:5

    Topics: Animals; Eflornithine; Female; Guanidines; Mice; Mitoguazone; Ornithine; Polyamines; Putrescine; Skin; Skin Physiological Phenomena; Spermidine

1982
Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1981, Volume: 35, Issue:10

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Eflornithine; Guanidines; Iodoacetates; Iodoacetic Acid; Mice; Mitoguazone; Neoplasms, Experimental; Ornithine; Ouabain; Polyamines; Putrescine; Spermidine

1981
Combined topical use of difluoromethyl ornithine and methylglyoxal bis (guanylhydrazone) in UV-irradiated mouse skin.
    The British journal of dermatology, 1982, Volume: 107, Issue:4

    Topics: Adenosylmethionine Decarboxylase; Animals; Eflornithine; Female; Guanidines; Male; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Skin; Spermidine; Ultraviolet Rays

1982
Delayed sensitization to heat by inhibitors of polyamine-biosynthetic enzymes.
    Cancer research, 1982, Volume: 42, Issue:12

    Topics: Animals; Carboxy-Lyases; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; Eflornithine; Female; Guanidines; Hot Temperature; Kinetics; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Ovary; Putrescine

1982
[Antitumor effects of polyamine synthesis inhibitors based on major premise of treatment for human malignant tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:10

    Topics: Animals; Cell Division; Drug Synergism; Drug Therapy, Combination; Eflornithine; Gastrointestinal Neoplasms; Guanidines; Mice; Mitoguazone; Neoplasms, Experimental; Ornithine; Polyamines; Stomach Neoplasms

1982
Effect of inhibitors of polyamine synthesis on activation of diapausing mouse blastocysts in vitro.
    Journal of reproduction and fertility, 1983, Volume: 68, Issue:2

    Topics: Animals; Blastocyst; Carboxy-Lyases; Cells, Cultured; Culture Media; Embryo Implantation; Embryo Implantation, Delayed; Female; Guanidines; In Vitro Techniques; Mice; Mice, Inbred Strains; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines

1983
A biochemical investigation of the adenovirus-induced G1 to S phase progression: thymidine kinase, ornithine decarboxylase, and inhibitors of polyamine biosynthesis.
    Journal of cellular physiology, 1982, Volume: 110, Issue:2

    Topics: Adenoviruses, Human; Animals; Blood; Calcium; Carboxy-Lyases; Cells, Cultured; Cricetinae; Dactinomycin; Enzyme Induction; Fibroblasts; Genes, Viral; Humans; Interphase; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Rats; Thymidine Kinase; Time Factors

1982
Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis; effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase.
    Life sciences, 1980, Jan-21, Volume: 26, Issue:3

    Topics: Animals; Carboxy-Lyases; Cells, Cultured; Cyclophosphamide; Female; Mammary Neoplasms, Experimental; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines

1980