ornithine has been researched along with folic acid in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (66.67) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Fetzer, O; Hynes, JB; Shane, B; Singh, SK | 1 |
| Bader, H; Forsch, RA; Freisheim, JH; Rosowsky, A | 1 |
| Freisheim, JH; Hynes, JB; Patil, SA; Shane, B; Singh, SK | 1 |
| Delcamp, TJ; Freisheim, JH; Kumar, AA; Price, EM; Smith, PL; Susten, SS | 1 |
| Bolanowska, WE; McGuire, JJ; Piper, JR | 1 |
| Gai, V; Gastaldi, L; Nattero, G | 1 |
| Bazzicalupo, G; Pietranera, P | 1 |
| Drago, U; Finotto, E; Ongaro, G | 1 |
| Avanzi, G; Meneghini, P | 1 |
| Rizzo, F | 1 |
| Catalfamo, G; Melotti, G; Soffritti, E | 1 |
| Merlini, R; Rossini, A | 1 |
| Ivaldi, A | 1 |
| Miracco, A; Orlando, V | 1 |
| Di Lorenzo, S | 1 |
| Nicoletti, A; Piro, E; Ruffolo, S | 1 |
| Floris, E; Mura, B | 1 |
| Fuller, HL; Keshavarz, K | 1 |
| Galivan, J; Rhee, MS; Rosowsky, A; Wright, JE | 1 |
| Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M; Peska, M | 1 |
| Forsch, RA; Moran, RG; Null, A; Rosowsky, A | 1 |
| Forsch, RA; Rosowsky, A; Vaidya, CM; Wright, JE | 1 |
| Assaraf, YG; Bunni, MA; Drori, S; Jansen, G; Kathmann, I; Mauritz, R; Noordhuis, P; Peters, GJ; Pinedo, HM; Priest, DG; Rosowsky, A; Schornagel, JH | 1 |
| Frühauf, J; Gangjee, A; Hou, Z; Matherly, LH; Ning, C; O'Connor, C; Tong, N; Wallace-Povirk, A | 1 |
24 other study(ies) available for ornithine and folic acid
| Article | Year |
|---|---|
Inhibition of hog liver folylpolyglutamate synthetase by 5-substituted 5,8-dideaza analogues of folic acid bearing a terminal L-ornithine residue.
Topics: Animals; Folic Acid; Kinetics; Liver; Ornithine; Peptide Synthases; Structure-Activity Relationship; Swine | 1992 |
Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain.
Topics: Aminopterin; Antineoplastic Agents; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methotrexate; Molecular Structure; Ornithine; Spectrophotometry; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1991 |
Inhibition of mammalian folylpolyglutamate synthetase and human dihydrofolate reductase by 5,8-dideaza analogues of folic acid and aminopterin bearing a terminal L-ornithine.
Topics: Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Liver; Ornithine; Oxidation-Reduction; Peptide Synthases; Substrate Specificity; Swine | 1989 |
Analogues of folate antagonists as affinity and fluorescent probes of dihydrofolate reductase structure and function.
Topics: Affinity Labels; Animals; Folic Acid; Leukemia L1210; Lysine; Methotrexate; Mice; Ornithine; Tetrahydrofolate Dehydrogenase; X-Ray Diffraction | 1986 |
Structural specificity of inhibition of human folylpolyglutamate synthetase by ornithine-containing folate analogs.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Folic Acid; Humans; Leukemia, Experimental; Methotrexate; Ornithine; Peptide Synthases; Rabbits; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
[Evaluation of the therapeutic possibilities offered by the combination: substrates of the Krebs-Henseleit cycle and vitamins in hepatic toxicoses].
Topics: Adult; Aged; Arginine; Chemical and Drug Induced Liver Injury; Citrulline; Female; Folic Acid; Humans; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[On a combination of amino acids and vitamins in the treatment of liver diseases].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical observations on the therapeutic efficiency of the combination: arginine HCl, citrulline, ornithine HCl, vitamin B-12, folic acid and nicotinamide in liver diseases and in anemic deficiency syndromes].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[On the therapeutic value of some amino acids in combination with vitamin B 12, folic acid and nicotinamide in the therapy of hepatic insufficiency].
Topics: Adolescent; Adult; Aged; Arginine; Biliary Tract Diseases; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Study on the behavior of the bromophthalein test in a group of patients affected by the hepatitis virus, treated with a combination of some amino acids, nicotinamide, folic acid and vitamin B-12].
Topics: Adolescent; Adult; Arginine; Citrulline; Female; Folic Acid; Hepatitis A; Humans; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinico-experimental findings on the use of a new liver protective agent].
Topics: Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical experimentation with a new pharmacologic combination having a liver protective and detoxicant scope].
Topics: Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical cases on the use of a combination of substances with hepatoprotective and detoxicant action in the treatment of some acute and chronic liver diseases].
Topics: Adolescent; Adult; Aged; Arginine; Child; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Association of vitamins and amino acids in the therapy of chronic liver diseases. Clinical results].
Topics: Adolescent; Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical considerations on the use of a new preparation with hepatoprotective action].
Topics: Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinico-metabolic observations on the use in therapy of a combination of vitamin B-12, folic acid, nicotinamide and amino acids of the arginine group in patients with chronic liver diseases].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Middle Aged; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
[Clinical experimentation with a new preparation: Polilevo].
Topics: Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
Relationship of arginine and methionine to creatine formation in chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays | 1971 |
Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
Topics: Animals; Biological Transport; DNA, Neoplasm; Folic Acid; Folic Acid Antagonists; Growth Inhibitors; In Vitro Techniques; Liver Neoplasms, Experimental; Methotrexate; Ornithine; Polyglutamic Acid; Pterins; Rats; Tumor Cells, Cultured | 1994 |
Arginine and ornithine metabolizing enzymes in testosterone-induced hypertrophic mouse kidney.
Topics: Animals; Arginase; Arginine; Eflornithine; Enzyme Induction; Female; Folic Acid; Hypertrophy; Kidney; Male; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Putrescine; Quinazolines; Sex Factors; Testosterone | 1995 |
5-deazafolate analogues with a rotationally restricted glutamate or ornithine side chain: synthesis and binding interaction with folylpolyglutamate synthetase.
Topics: Cell Division; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Glutamic Acid; Humans; Ornithine; Peptide Synthases; Recombinant Proteins | 1999 |
The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta
Topics: 4-Aminobenzoic Acid; Aminopterin; Antineoplastic Agents; Binding Sites; Cell Division; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Humans; Ornithine; Pterins; Reducing Agents; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 2000 |
Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Topics: Biological Transport; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; gamma-Glutamyl Hydrolase; Glutamates; Guanine; Homeostasis; Humans; Leukemia; Methotrexate; Ornithine; Pemetrexed; Peptide Synthases; Polyglutamic Acid; Pterins; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Folate transporter dynamics and therapy with classic and tumor-targeted antifolates.
Topics: Biological Transport; Cell Proliferation; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Methotrexate; Neoplasms; Ornithine; Pemetrexed; Proton-Coupled Folate Transporter; Pterins; Reduced Folate Carrier Protein | 2021 |