ornithine and alpha-methylornithine

ornithine has been researched along with alpha-methylornithine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199030 (88.24)18.7374
1990's3 (8.82)18.2507
2000's1 (2.94)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knutson, JC; Morris, DR1
Bowlin, TL; Flescher, E; Talal, N1
Baby, TG; Joseph, K1
Keir, HM; Wallace, HM1
Ascioti, C; Audino, MG; De Sarro, A; De Sarro, GB; Libri, V; Nisticò, G1
Grens, A; Scheffler, IE; Steglich, C1
Albor, A; Blachier, F; Camara, J; Malaisse, WJ; Mourtada, A; Sener, A; Valverde, I1
Hidaka, H; Kawakami, K; Ohmura, T; Onoue, K; Yamamoto, Y1
Członkowska, M; Guszkiewicz, A; Zwierzchowski, L1
Gaget, C; Heintzelmann, B; Wagner, J; Wolf, E1
Königk, E; Putfarken, B1
Anehus, S; Heby, O; Oredsson, SM; Persson, L1
Kawazoe, Y; Shiokawa, K; Tashiro, K; Yamana, K1
Ishikawa, Y; Kaiser-Kupfer, MI; Kuwabara, T1
Caldarera, CM; Clô, C; Coccolini, MN; Tantini, B1
Gordon, AM; Keir, HM; Pearson, CK; Wallace, HM1
Marton, LJ; Oredsson, SM1
Anehus, S; Heby, O; Oredsson, S1
Deen, DF; Marton, LJ; Seidenfeld, J1
Böhlen, P; Grosshans, E; Grove, J; Henry, M; Koch-Weser, J; Schechter, PJ; Tell, G1
Aleksijevic, A; Blée, E; Schuber, F1
Choi, J; Scheffler, IE1
Emanuelsson, H; Heby, O1
Bacchi, CJ; Garofalo, J; Hutner, SH; McLaughlin, SD; Mockenhaupt, D; Trueba, G1
Hori, C; Oka, T; Perry, JW; Sakai, T1
Bellett, AJ; Cheetham, BF1
Kersten, H; Kersten, W; Mach, M1
Harada, JJ; Morris, DR; Porter, CW1
Heby, O; Linden, M; Oredsson, S1
Marton, LJ; Seidenfeld, J1
Forbes, WR; Yeager, RK1
Kawabata, A; Muguruma, H; Takagi, H; Tanaka, M1
Harada, JJ; Morris, DR1
Beliaeva, TN; Bulychev, AG; Leont'eva, EA; Mozhenok, TP1

Other Studies

34 other study(ies) available for ornithine and alpha-methylornithine

ArticleYear
Cellular polyamine depletion reduces DNA synthesis in isolated lymphocyte nuclei.
    Biochimica et biophysica acta, 1978, Sep-27, Volume: 520, Issue:2

    Topics: Animals; Cattle; Cell Nucleus; DNA; DNA Replication; Guanidines; Kinetics; Lymphocytes; Mitoguazone; Ornithine; Putrescine; Spermidine; Spermine

1978
Regulation of IL-2 production by mononuclear cells from rheumatoid arthritis synovial fluids.
    Clinical and experimental immunology, 1992, Volume: 87, Issue:3

    Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Female; Humans; Interleukin-2; Male; Middle Aged; Monocytes; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Prostaglandin Antagonists; Putrescine; Synovial Fluid

1992
Early developmental profile of ornithine decarboxylase in the frog, Microhyla ornata and its regulation by polyamines.
    The Journal of experimental zoology, 1991, Volume: 258, Issue:2

    Topics: Animals; Embryo, Nonmammalian; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Ranidae; Spermidine

1991
Factors affecting polyamine excretion from mammalian cells in culture. Inhibitors of polyamine biosynthesis.
    FEBS letters, 1986, Jan-01, Volume: 194, Issue:1

    Topics: Acetylation; Animals; Canavanine; Cell Line; Cricetinae; DNA; Kidney; Mitoguazone; Ornithine; Polyamines; Proteins; Pyruvaldehyde; RNA

1986
Behavioural and electrocortical effects after injection of two ornithine decarboxylase inhibitors into several areas of the brain in the rat.
    Neuropharmacology, 1989, Volume: 28, Issue:11

    Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Cerebral Cortex; Eflornithine; Electroencephalography; Hippocampus; Injections; Injections, Intraventricular; Male; Muscimol; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Thalamus

1989
Chinese hamster cells deficient in ornithine decarboxylase activity: reversion by gene amplification and by azacytidine treatment.
    Somatic cell and molecular genetics, 1985, Volume: 11, Issue:1

    Topics: Animals; Azacitidine; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Gene Amplification; Mutation; Ornithine; Ornithine Decarboxylase; RNA, Messenger

1985
Stimulus-secretion coupling of arginine-induced insulin release. Metabolism of L-arginine and L-ornithine in pancreatic islets.
    Biochimica et biophysica acta, 1989, Sep-19, Volume: 1013, Issue:2

    Topics: Animals; Arginase; Arginine; Glucose; Glutamates; Insulin; Islets of Langerhans; Models, Biological; Ornithine; Oxidation-Reduction; Polyamines; Rats; Urea

1989
Induction and regulation of human interleukin 2 gene expression: significance of protein kinase C activation.
    Journal of biochemistry, 1986, Volume: 100, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Enzyme Activation; Gene Expression Regulation; Humans; Interleukin-2; Isoquinolines; Lymphocytes; Mitoguazone; Ornithine; Phytohemagglutinins; Piperazines; Prostaglandins E; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine

1986
Effect of polyamine limitation on DNA synthesis and development of mouse preimplantation embryos in vitro.
    Journal of reproduction and fertility, 1986, Volume: 76, Issue:1

    Topics: Animals; Blastocyst; Culture Media; DNA; Eflornithine; Embryonic Development; Female; In Vitro Techniques; Mice; Mitoguazone; Ornithine; Polyamines; Pregnancy; Spermine

1986
Resolution of the enantiomers of various alpha-substituted ornithine and lysine analogs by high-performance liquid chromatography with chiral eluant and by gas chromatography on Chirasil-Val.
    Analytical biochemistry, 1987, Volume: 164, Issue:1

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Copper; Eflornithine; Indicators and Reagents; Lysine; Organic Chemicals; Ornithine; Ornithine Decarboxylase Inhibitors; Stereoisomerism

1987
Ornithine decarboxylase of Plasmodium falciparum: a peak-function enzyme and its inhibition by chloroquine.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1985, Volume: 36, Issue:2

    Topics: Animals; Chloroquine; Drug Interactions; Eflornithine; Hydrogen-Ion Concentration; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plasmodium falciparum; Putrescine; Spermidine

1985
Ornithine decarboxylase inhibitors increase the cellular content of the enzyme: implications for translational regulation.
    Biochemical and biophysical research communications, 1985, Aug-30, Volume: 131, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cycloheximide; DNA; Eflornithine; Half-Life; Nucleic Acid Hybridization; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; RNA, Messenger

1985
Effects of various ammonium salts, amines, polyamines and alpha-methylornithine on rRNA synthesis in neurula cells of Xenopus laevis and Xenopus borealis.
    Cell differentiation, 1986, Volume: 18, Issue:2

    Topics: Amines; Animals; Carboxy-Lyases; Cell Differentiation; Cells, Cultured; Ornithine; Polyamines; Quaternary Ammonium Compounds; RNA, Ribosomal; Xenopus; Xenopus laevis

1986
Toxic effects of ornithine and its related compounds on the retina.
    Advances in experimental medicine and biology, 1982, Volume: 153

    Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Lysine; Ornithine; Pigment Epithelium of Eye; Proline; Putrescine; Rats; Rats, Inbred Strains; Retina

1982
Increased sensitivity of heart cell cultures to norepinephrine after exposure to polyamine synthesis inhibitors.
    Life sciences, 1980, Jul-07, Volume: 27, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Heart; Norepinephrine; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Pyruvaldehyde; Time Factors

1980
Activation of ADP-ribosyltransferase in polyamine-depleted mammalian cells.
    The Biochemical journal, 1984, Apr-01, Volume: 219, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Cells, Cultured; Centrifugation, Density Gradient; Chromatography; Cricetinae; DNA; Enzyme Activation; Fibroblasts; Kidney; Mitoguazone; Nucleotidyltransferases; Ornithine; Poly(ADP-ribose) Polymerases; Spermidine; Spermine

1984
Potential uses of polyamine biosynthesis inhibitors in tumor therapy.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Antineoplastic Agents; Cell Cycle; DNA Repair; Drug Therapy, Combination; Eflornithine; Humans; Mitoguazone; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Sister Chromatid Exchange

1984
Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.
    Biochemical and biophysical research communications, 1980, May-14, Volume: 94, Issue:1

    Topics: Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cell Division; Eflornithine; Kinetics; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine; Spermidine; Spermine

1980
Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1980, Volume: 38, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA; DNA, Neoplasm; Eflornithine; Guanidines; Mitoguazone; Ornithine; Polyamines; Putrescine; Radiation Tolerance; Rats; Spermidine; Spermine; X-Rays

1980
[Polyamines in psoriasis].
    Annales de dermatologie et de venereologie, 1980, Volume: 107, Issue:5

    Topics: Anthralin; Carboxy-Lyases; Chemical Phenomena; Chemistry; Double-Blind Method; Eflornithine; Humans; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Psoriasis; PUVA Therapy

1980
Comparative role of polyamines in division and plastid differentiation of Euglena gracilis.
    Biochimica et biophysica acta, 1981, Volume: 675, Issue:2

    Topics: Carboxy-Lyases; Cell Differentiation; Cell Division; Euglena gracilis; Ornithine; Ornithine Decarboxylase Inhibitors; Photic Stimulation; Polyamines; Temperature

1981
A mutant of Chinese hamster ovary cells resistant to alpha-methyl- and alpha-difluoromethylornithine.
    Somatic cell genetics, 1981, Volume: 7, Issue:2

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Eflornithine; Female; Kinetics; Mutation; Ornithine; Ornithine Decarboxylase; Ovary; Time Factors

1981
Role of the polyamines in germ cell differentiation and in early embryonic development.
    Medical biology, 1981, Volume: 59, Issue:5-6

    Topics: Animals; Cell Differentiation; Chick Embryo; Eflornithine; Embryo, Nonmammalian; Oogenesis; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Polychaeta; Sea Urchins

1981
Ornithine decarboxylase in Trypanosoma brucei brucei: evidence for selective toxicity of difluoromethylornithine.
    The Journal of protozoology, 1982, Volume: 29, Issue:3

    Topics: Animals; Carboxy-Lyases; Eflornithine; Enzyme Induction; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Trypanosoma brucei brucei

1982
Putrescine and the regulation of S-adenosyl-L-methionine decarboxylase in cultured mouse mammary gland.
    Biochimica et biophysica acta, 1980, Aug-07, Volume: 614, Issue:2

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Enzyme Activation; Female; Hypotonic Solutions; Insulin; Mammary Glands, Animal; Mice; Organ Culture Techniques; Ornithine; Ornithine Decarboxylase Inhibitors; Putrescine

1980
A biochemical investigation of the adenovirus-induced G1 to S phase progression: thymidine kinase, ornithine decarboxylase, and inhibitors of polyamine biosynthesis.
    Journal of cellular physiology, 1982, Volume: 110, Issue:2

    Topics: Adenoviruses, Human; Animals; Blood; Calcium; Carboxy-Lyases; Cells, Cultured; Cricetinae; Dactinomycin; Enzyme Induction; Fibroblasts; Genes, Viral; Humans; Interphase; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Rats; Thymidine Kinase; Time Factors

1982
Regulation of tRNA methyltransferase activities by spermidine and putrescine. Inhibition of polyamine synthesis and tRNA methylation by alpha-methylornithine or 1,3-diaminopropan-2-ol in Dictyostelium.
    The Biochemical journal, 1982, Jan-15, Volume: 202, Issue:1

    Topics: Diamines; Dictyostelium; Methylation; Nucleosides; Ornithine; Propanolamines; Putrescine; RNA, Transfer; Spermidine; tRNA Methyltransferases

1982
Induction of polyamine limitation in Chinese hamster ovary cells by alpha-methylornithine.
    Journal of cellular physiology, 1981, Volume: 107, Issue:3

    Topics: Animals; Cell Division; Cricetinae; Cricetulus; Female; Ornithine; Ovary; Polyamines; Putrescine; Spermidine

1981
Cytocidal effect of alpha-methylornithine, a competitive inhibitor of ornithine decarboxylase, on ehrlich ascites tumor cells in vivo.
    Cancer letters, 1980, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cell Cycle; Male; Mice; Ornithine; Ornithine Decarboxylase Inhibitors

1980
Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Animals; Brain Neoplasms; Carboxy-Lyases; Cell Division; Cells, Cultured; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Spermidine; Spermine

1980
Inhibition of Dugesia tigrina auricle regeneration by inhibitors of polyamine synthesis.
    Experientia, 1980, Apr-15, Volume: 36, Issue:4

    Topics: Aldehydes; Animals; Ornithine; Polyamines; Putrescine; Pyruvaldehyde; Regeneration; Spermidine; Spermine; Turbellaria

1980
NG-nitro-L-arginine methyl ester and alpha-methyl-L-ornithine inhibit kyotorphin synthetase from rat brain.
    Peptides, 1995, Volume: 16, Issue:7

    Topics: Animals; Arginine; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Ornithine Decarboxylase; Peptide Synthases; Rats; Rats, Wistar

1995
Cell cycle parameters of Chinese hamster ovary cells during exponential, polyamine-limited growth.
    Molecular and cellular biology, 1981, Volume: 1, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; CHO Cells; Cricetinae; Female; Ornithine; Ovary; Polyamines; Putrescine

1981
[Effect of polyamine synthesis inhibitors separately and in combination with epidermal growth factor on fusion of lysosomes with phagosomes and F-actin level in mouse peritoneal macrophages].
    Tsitologiia, 2000, Volume: 42, Issue:6

    Topics: Actins; Animals; Antineoplastic Agents; Cells, Cultured; Eflornithine; Enzyme Inhibitors; Epidermal Growth Factor; Lysosomes; Macrophages, Peritoneal; Membrane Fusion; Mice; Mice, Inbred C57BL; Ornithine; Ornithine Decarboxylase Inhibitors; Phagosomes

2000