ornithine alpha-ketoglutarate and ornithine

ornithine alpha-ketoglutarate has been researched along with ornithine in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (20.00)	18.7374
1990's	31 (38.75)	18.2507
2000's	26 (32.50)	29.6817
2010's	6 (7.50)	24.3611
2020's	1 (1.25)	2.80

Authors

Authors	Studies
Pistorio, A	1
Ali, MR; Holaday, NJ; Jeevanandam, M	1
Ali, R; Hammarqvist, F; Vinnars, E; Wernerman, J	1
Payne-James, JJ; Silk, DB	1
Agneray, J; Coudray-Lucas, C; Cynober, L; Ekindjian, OG; Salvucci, M; Vaubourdolle, M	1
Bouchon, Y; Chanson, L; Debry, G; Merle, M; Michon, J	1
Ali, MR; Hammarkvist, F; Vinnars, E; Wernerman, J	1
Bourel, M; Brissot, P; Desvergne, B; Deugnier, Y; Lescoat, G; Loreal, O; Pasdeloup, N	1
Hammarqvist, F; Vinnars, E; von der Decken, A; Wernerman, J	1
Aussel, C; Coudray-Lucas, C; Cynober, L; Giboudeau, J; Lioret, N; Saizy, R; Vaubourdolle, M	1
Debout, J; Krivosic-Horber, R; Salvetti, B	1
Felber, JP; Krassowski, J; Maeder, E; Rousselle, J	2
Bouchon, Y; Merle, M	1
Cynober, L; Dore, A; Giboudeau, J; Vaubourdolle, M	1
Cynober, L; Giboudeau, J; Lioret, N; Nguyen Dinh, F; Saizy, R	1
Crignon, JJ; Delbar, M; Demarcq, JM; Trochu, G	1
Blok, IuE; Loginov, AS	1
Filoche, B; Herlin, F; Lefebvre, V	1
Charpentier, C; Lemonnier, F; Molimard, R	1
Baracos, VE; Cynober, L; Field, CJ; Le Bricon, T	1
Saltzman, JR; Varanasi, RV	1
Albarede, JL; Brocker, P; Poynard, T; Vellas, B	1
Baracos, VE; Cynober, L; Le Bricon, T	1
Buchman, AL; Cynober, L; Goulet, O; Marti-Henneberg, C; Moukarzel, AA; Rappaport, R; Ricour, C; Salas, JS	1
Coudray-Lucas, C; Cynober, L; Fontagné, J; Giroud, JP; Le Boucher, J; Roch-Arveiller, M; Tissot, M	1
Holaday, NJ; Jeevanandam, M; Petersen, SR	1
Bettonica, C; Cuadrado, S; de Oca, J; Martín, E; Montañés, T; Vallet, J	1
Coudray-Lucas, C; Cynober, L; De Bandt, JP; Giboudeau, J; Le Bricon, T; Lim, SK; Lioret, N; Plassart, F; Saizy, R; Schlegel, L	1
Coudray-Lucas, C; Cynober, LA; Ekindjian, OG; Jardel, A; Lasnier, E; Le Boucher, J	1
Bettonica, C; Cuadrado, S; de Oca, J; Garcia, A; Jaurrieta, E; Martín, E; Montañés, T; Vallet, J	1
Czernichow, B; Galluser, M; Gossé, F; Nsi-Emvo, E; Raul, F	1
Cynober, L; Farges, MC; Le Boucher, J; Obled, C	1
Boltz-Nitulescu, G; Fuegger, R; Goetzinger, P; Holzer, S; Leutmezer, F; Oehler, R; Rath, V; Reissner, CM; Roth, E; Spittler, A; Wrba, F	1
Duranton, B; Gossé, F; Raul, F; Schleiffer, R	1
Coudray-Lucas, C; Cynober, L; De Bandt, JP; Giboudeau, J; Lim, SK; Lioret, N; Saizy, R	1
Dorf, G	1
Brousse, N; Colomb, V; Coudray-Lucas, C; Cynober, L; De Bandt, JP; Dumas, F; Goulet, O; Lavie, S; Le Boucher, J; Ricour, C	1
Coudray-Lucas, C; Cynober, L; Delaforge, M; Fontagné, J; Le Boucher, J; Muntaner, O; Roch-Arveiller, M	1
Caldefie, F; Chassagne, J; Chauveau, B; Cynober, LA; Felgines, C; Moinard, C; Vasson, MP; Walrand, S	1
Cynober, LA	1
Cynober, L; Farges, MC; Le Boucher, J; Minet, R; Vasson, MP	1
Cynober, LA; De Bandt, JP	1
Jeevanandam, M; Petersen, SR	1
Baracos, VE; Bussière, FI; Cynober, LA; Farges, MC; Field, CJ; Le Boucher, J; Robinson, LE	1
Donati, L; Pongelli, G; Signorini, MS; Ziegler, F	1
Bidner, TD; Guzik, AC; Ladner, JP; Matthews, JO; Southern, LL	1
Caldefie, F; Cynober, L; Felgines, C; Moinard, C; Vasson, MP; Walrand, S	1
Carsin, H; Coudray-Lucas, C; Cynober, L; De Bandt, JP; Le Bever, H	1
Barbut, F; Coudray-Lucas, C; Cynober, L; Jardel, A; Le Boucher, J; Schlegel, L; Zarrabian, S	1
Boobis, LH; Bowtell, JL; Bruce, M; Constantin-Teodosiu, D; Greenhaff, PL; Williams, C	1
Dechelotte, P; Nitenberg, G	1
Caldefie, F; Chassagne, J; Cynober, L; Moinard, C; Tridon, A; Vasson, MP; Walrand, S	1
Reynolds, TM	1
Holovach, IIu; Mytnyk, ZM; Neĭko, IeM	1
Dakshayani, KB; Subramanian, P; Velvizhi, S	2
Aussel, C; Blonde-Cynober, F; Cynober, L	1
Cynober, L; Darquy, S; De Bandt, JP; Reach, G; Schneid, C	1
Cynober, L; Darquy, S; De Bandt, JP; Reach, G; Schneid, C; Torres, E	1
HARPER, AE; WALDORF, MA	1
Genton, L; Hirschel, B; Karsegard, VL; Pichard, C; Raguso, CA	1
Cynober, L; Dauge, V; Moinard, C	1
Cynober, L	1
Coudray-Lucas, C; Cynober, L; Jardel, A; Pernet, P; Schneid, C	1
Blanc, MC; Bonnefont-Rousselot, D; Cynober, L; De Bandt, JP; Genthon, C; Le Tourneau, A; Schuster, H; Thérond, P	1
Alexandre-Gouabau, MC; Bleiberg-Daniel, F; Cynober, L; Lardeux, B; Moinard, C; Nakib, S; Segaud, F	1
Arnaud-Battandier, F; Cynober, L; Loï, C; Nakib, S; Neveux, N	1
Brodzki, A; Krupski, W; Pasternak, K; Sliwa, E; Tatara, MR	1
Bishoff, L; Cynober, L; Garbay, C; Hamani, D; Loï, C; Moinard, C; Neveux, N	1
Coudray-Lucas, C; Cynober, L; Jardel, A; Lasnier, E; Le Boucher, J	1
Attaix, D; Combaret, L; Cynober, L; Moinard, C; Neveux, N; Segaud, F	1
Bourdel Marchasson, I; Constans, T; Kerihuel, JC; Kern, J; Lerebours, E; Meaume, S; Teot, L	1
Walrand, S	1
Gibson, KM; Knerr, I; Vockley, J; Weinhold, N	1
Garcia, JH; Gonçalves, ES; Guimarães, SB; Prado Neto, AX; Rabelo, CM; Vasconcelos, PR	1
Cunha, RM; Guimarães Filho, A; Guimarães, SB; Vasconcelos, PR	1
Danilla, S; El Dib, R; Henderson, TO; Murray, A; Serra, R; Tan, HB; Wasiak, J	1
Bailey, C; Cantor, NL; Ernst, SL; Gappmaier, E; Longo, N; Pasquali, M; Price, LB	1
Jin, S; Li, T; Li, Y; Su, W; Tian, J; Wang, P; Yao, K; Yin, J	1

Reviews

10 review(s) available for ornithine alpha-ketoglutarate and ornithine

Article	Year
Novel substrates and nutritional support: possible role of ornithine alpha-ketoglutarate. The Proceedings of the Nutrition Society, 1990, Volume: 49, Issue:3 Topics: Enteral Nutrition; Humans; Nitrogen; Nutritional Physiological Phenomena; Ornithine; Parenteral Nutrition	1990
Ornithine oxoglutarate therapy improves nutrition status. Nutrition reviews, 1995, Volume: 53, Issue:4 Pt 1 Topics: Aged; Aging; Burns; Humans; Nutritional Status; Ornithine; Wounds and Injuries	1995
The use of alpha-ketoglutarate salts in clinical nutrition and metabolic care. Current opinion in clinical nutrition and metabolic care, 1999, Volume: 2, Issue:1 Topics: Adjuvants, Immunologic; Animals; Dietary Supplements; Glutamine; Humans; Intestines; Ketoglutaric Acids; Nutritional Physiological Phenomena; Ornithine	1999
Amino acids with anabolic properties. Current opinion in clinical nutrition and metabolic care, 1998, Volume: 1, Issue:3 Topics: Amino Acids; Animals; Arginine; Glutamine; Humans; Immune System; Intestinal Mucosa; Nutritional Support; Ornithine; Proteins	1998
Is immune nutrition the Holy Grail for cancer patients? Nestle Nutrition workshop series. Clinical & performance programme, 2000, Volume: 4 Topics: Arginine; Fatty Acids, Unsaturated; Glutamine; Hospitalization; Humans; Immunotherapy; Length of Stay; Neoplasms; Nutritional Physiological Phenomena; Nutritional Support; Ornithine; Treatment Outcome	2000
The future of nutrition and wound healing. Journal of tissue viability, 2001, Volume: 11, Issue:1 Topics: Enteral Nutrition; Growth Substances; Humans; Nutritional Physiological Phenomena; Ornithine; Parenteral Nutrition; Vitamins; Wound Healing	2001
Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients. Nutrition (Burbank, Los Angeles County, Calif.), 2003, Volume: 19, Issue:1 Topics: Aged; Aged, 80 and over; Aging; Female; Glutamine; Humans; Male; Nutrition Disorders; Nutritional Status; Ornithine	2003
Ornithine alpha-ketoglutarate as a potent precursor of arginine and nitric oxide: a new job for an old friend. The Journal of nutrition, 2004, Volume: 134, Issue:10 Suppl Topics: Animals; Arginine; Humans; Nitric Oxide; Ornithine; Prodrugs	2004
Advances and challenges in the treatment of branched-chain amino/keto acid metabolic defects. Journal of inherited metabolic disease, 2012, Volume: 35, Issue:1 Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Animals; Creatinine; Humans; Maple Syrup Urine Disease; Mass Spectrometry; Metabolomics; Mice; Mice, Knockout; Mice, Transgenic; Ornithine; Phenotype; Risk	2012
Immunonutrition as an adjuvant therapy for burns. The Cochrane database of systematic reviews, 2014, Issue:12 Topics: Amino Acids, Branched-Chain; Burns; Fatty Acids, Omega-3; Glutamine; Humans; Length of Stay; Malnutrition; Nutrition Therapy; Ornithine; Randomized Controlled Trials as Topic; Soybean Proteins; Vitamins; Wound Infection	2014

Trials

12 trial(s) available for ornithine alpha-ketoglutarate and ornithine

Article	Year
[Effect of ornithine oxoglutarate on the duration and quality of wound healing in extensive reparative and plastic surgical methods]. Annales de chirurgie plastique et esthetique, 1989, Volume: 34, Issue:5 Topics: Adult; Double-Blind Method; Female; Humans; Ornithine; Placebos; Random Allocation; Surgery, Plastic; Time Factors; Wound Healing	1989
Ornithine-alpha-ketoglutarate improves skeletal muscle protein synthesis as assessed by ribosome analysis and nitrogen use after surgery. Annals of surgery, 1987, Volume: 206, Issue:5 Topics: Cholecystectomy; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Muscle Proteins; Muscles; Nitrogen; Ornithine; Parenteral Nutrition, Total; Polyribosomes; Postoperative Period; Random Allocation; Ribosomes; Urea	1987
[A controlled trial of ornithine alpha-ketoglutarate in neuro-traumatology]. Cahiers d'anesthesiologie, 1986, Volume: 34, Issue:6 Topics: Adolescent; Adult; Brain Injuries; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Ornithine; Random Allocation; Spinal Injuries	1986
A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects. Age and ageing, 1994, Volume: 23, Issue:4 Topics: Activities of Daily Living; Acute Disease; Aged; Appetite; Convalescence; Costs and Cost Analysis; Double-Blind Method; Humans; Nutrition Disorders; Nutritional Status; Ornithine; Quality of Life	1994
Ornithine alpha-ketoglutarate metabolism after enteral administration in burn patients: bolus compared with continuous infusion. The American journal of clinical nutrition, 1997, Volume: 65, Issue:2 Topics: Adult; Arginine; Burns; Enteral Nutrition; Female; Half-Life; Humans; Infusions, Parenteral; Male; Ornithine; Random Allocation	1997
A randomized controlled trial of the influence of the mode of enteral ornithine alpha-ketoglutarate administration in burn patients. The Journal of nutrition, 1998, Volume: 128, Issue:3 Topics: Adult; Burns; Dose-Response Relationship, Drug; Enteral Nutrition; Humans; Infusion Pumps; Male; Middle Aged; Ornithine; Soybean Proteins; Treatment Outcome	1998
Substrate fuel kinetics in enterally fed trauma patients supplemented with ornithine alpha ketoglutarate. Clinical nutrition (Edinburgh, Scotland), 1999, Volume: 18, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Calorimetry, Indirect; Energy Metabolism; Enteral Nutrition; Female; Glucose; Glycerol; Humans; Injury Severity Score; Male; Middle Aged; Multiple Trauma; Ornithine; Oxygen Consumption; Proteins; Trauma Centers	1999
Nutritional and clinical efficacy of ornithine alpha-ketoglutarate in severe burn patients. Clinical nutrition (Edinburgh, Scotland), 1999, Volume: 18, Issue:5 Topics: Adult; Body Weight; Burns; Double-Blind Method; Female; Humans; Male; Nitrogen; Nutritional Status; Ornithine; Prealbumin; Retinol-Binding Proteins; Wound Healing	1999
Ornithine alpha-ketoglutarate improves wound healing in severe burn patients: a prospective randomized double-blind trial versus isonitrogenous controls. Critical care medicine, 2000, Volume: 28, Issue:6 Topics: Adult; Burns; Double-Blind Method; Enteral Nutrition; Female; Humans; Injury Severity Score; Male; Ornithine; Prospective Studies; Soybean Proteins; Wound Healing	2000
L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions. Nutrition (Burbank, Los Angeles County, Calif.), 2004, Volume: 20, Issue:6 Topics: Adult; Analysis of Variance; Body Composition; CD4 Lymphocyte Count; Diet Records; Dietary Supplements; Digestive System; Double-Blind Method; Electric Impedance; Exercise Test; Female; Hand Strength; HIV Seropositivity; HIV Wasting Syndrome; Humans; Immune System; Male; Nutritional Status; Ornithine; Physical Endurance; Prospective Studies; Skinfold Thickness; Viral Load	2004
Efficacy and safety of ornithine alpha-ketoglutarate in heel pressure ulcers in elderly patients: results of a randomized controlled trial. The journal of nutrition, health & aging, 2009, Volume: 13, Issue:7 Topics: Aged; Aged, 80 and over; Double-Blind Method; Female; Foot Ulcer; Heel; Humans; Male; Ornithine; Pressure Ulcer; Reference Values; Skin; Statistics, Nonparametric; Wound Healing	2009
Anaplerotic therapy in propionic acidemia. Molecular genetics and metabolism, 2017, Volume: 122, Issue:1-2 Topics: Amino Acids; Ammonia; Carbon-Carbon Ligases; Child; Child, Preschool; Citrates; Citric Acid; Citric Acid Cycle; Dietary Supplements; Female; Glutamine; Humans; Lactic Acid; Male; Ornithine; Propionic Acidemia; Treatment Outcome	2017

Other Studies

58 other study(ies) available for ornithine alpha-ketoglutarate and ornithine

Article	Year
[Observations on viral hepatitis in community medicine]. La Clinica terapeutica, 1992, Volume: 140, Issue:6 Topics: Biochemical Phenomena; Biochemistry; Cysteine; Glutamates; Glutamic Acid; Hepatitis, Viral, Human; Humans; Interferons; Neurotransmitter Agents; Ornithine; Pyruvates; Pyruvic Acid	1992
Altered tissue polyamine levels due to ornithine-alpha-ketoglutarate in traumatized growing rats. Metabolism: clinical and experimental, 1992, Volume: 41, Issue:11 Topics: Acetylation; Animals; Femur; Food, Fortified; Intestines; Liver; Male; Muscles; Ornithine; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine	1992
Effects of an amino acid solution enriched with either branched chain amino acids or ornithine-alpha-ketoglutarate on the postoperative intracellular amino acid concentration of skeletal muscle. The British journal of surgery, 1990, Volume: 77, Issue:2 Topics: Amino Acids; Amino Acids, Branched-Chain; Female; Glutamine; Humans; Male; Middle Aged; Muscles; Ornithine; Parenteral Nutrition, Total; Postoperative Period; Solutions	1990
Action of ornithine alpha ketoglutarate on DNA synthesis by human fibroblasts. In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1990, Volume: 26, Issue:2 Topics: Cells, Cultured; DNA; Female; Fibroblasts; Humans; Ornithine; Pregnancy; Thymidine; Tritium	1990
Glutamine and ornithine-alpha-ketoglutarate but not branched-chain amino acids reduce the loss of muscle glutamine after surgical trauma. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:8 Suppl 1 Topics: Abdomen; Amino Acids; Amino Acids, Branched-Chain; Glutamine; Humans; Muscles; Nitrogen; Ornithine; Parenteral Nutrition, Total	1989
Modulation of albumin secretion by ornithine alpha-ketoglutarate in adult rat hepatocyte cultures and a human hepatoma cell line (HepG2). Annals of nutrition & metabolism, 1989, Volume: 33, Issue:5 Topics: Albumins; Animals; Cells, Cultured; Humans; Liver; Liver Neoplasms, Experimental; Ornithine; Rats	1989
Influence of enterally administered ornithine alpha-ketoglutarate on hormonal patterns in burn patients. Burns, including thermal injury, 1987, Volume: 13, Issue:5 Topics: Adolescent; Adult; Blood Glucose; Burns; C-Peptide; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Kinetics; Male; Middle Aged; Ornithine	1987
The effect of ornithine alpha-ketoglutarate on growth hormone (GH) and prolactin (PRL) release in normal subjects. Endokrynologia Polska, 1986, Volume: 37, Issue:1 Topics: Adult; Growth Hormone; Humans; Male; Ornithine; Pituitary Function Tests; Pituitary Gland, Anterior; Prolactin	1986
[Oral ornithine alpha-ketoglutarate in the prevention of local complications of plastic surgery. Double-blind controlled study of 42 cases]. Annales de chirurgie plastique et esthetique, 1984, Volume: 29, Issue:4 Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Middle Aged; Ornithine; Surgery, Plastic; Wound Healing	1984
Kinetics and metabolic effects of orally administered ornithine alpha-ketoglutarate in healthy subjects fed with a standardized regimen. The American journal of clinical nutrition, 1984, Volume: 39, Issue:4 Topics: Administration, Oral; Adult; Amino Acids; Blood Glucose; Female; Humans; Insulin; Ketoglutaric Acids; Kinetics; Male; Metabolism; Ornithine; Urea	1984
Effect of enterally administered ornithine alpha-ketoglutarate on plasma and urinary amino acid levels after burn injury. The Journal of trauma, 1984, Volume: 24, Issue:7 Topics: Adolescent; Adult; Amino Acids; Burns; Enteral Nutrition; Female; Humans; Male; Middle Aged; Ornithine	1984
[Effects of ornithine alpha-ketoglutarate on the nutritional state of intensive-care patients]. Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:3 Topics: Blood Proteins; Cholesterol; Creatinine; Critical Care; Enteral Nutrition; Humans; Nitrogen; Nutritional Physiological Phenomena; Ornithine; Parenteral Nutrition; Prealbumin; Serum Albumin; Transferrin	1984
[Diagnosis and treatment of hyperazotemia in liver cirrhosis]. Terapevticheskii arkhiv, 1983, Volume: 55, Issue:9 Topics: Ammonia; Drug Therapy, Combination; Female; Humans; Lactulose; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Ornithine; Uremia	1983
[Use of ornithine alpha-ketoglutarate in malnourished cancer patients]. Medecine & chirurgie digestives, 1982, Volume: 11, Issue:3 Topics: Aged; Digestive System Neoplasms; Female; Humans; Male; Middle Aged; Nutrition Disorders; Ornithine; Parenteral Nutrition	1982
The effect of ornithine-alpha-ketoglutarate on insulin and glucagon secretion in normal subjects. Acta endocrinologica, 1981, Volume: 98, Issue:2 Topics: Adult; Glucagon; Humans; Insulin; Insulin Secretion; Ketoglutaric Acids; Male; Ornithine; Pancreas	1981
[Changes of plasma amino acids in cirrhotics treated with ornithine salts]. Annals of nutrition & metabolism, 1982, Volume: 26, Issue:1 Topics: Amino Acids; Glucose; Humans; Ketoglutaric Acids; Liver Cirrhosis; Ornithine	1982
Supplemental nutrition with ornithine alpha-ketoglutarate in rats with cancer-associated cachexia: surgical treatment of the tumor improves efficacy of nutritional support. The Journal of nutrition, 1995, Volume: 125, Issue:12 Topics: Amino Acids; Animals; Body Weight; Cachexia; Combined Modality Therapy; Eating; Food, Fortified; Glutamine; Glycine; Intestine, Small; Liver Neoplasms, Experimental; Male; Muscle, Skeletal; Neoplasm Proteins; Nitrogen; Ornithine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured	1995
Ornithine alpha-ketoglutarate limits muscle protein breakdown without stimulating tumor growth in rats bearing Yoshida ascites hepatoma. Metabolism: clinical and experimental, 1994, Volume: 43, Issue:7 Topics: Amino Acids; Animals; Body Weight; Eating; Liver Neoplasms, Experimental; Male; Muscle Proteins; Muscles; Ornithine; Rats; Rats, Sprague-Dawley	1994
Growth retardation in children receiving long-term total parenteral nutrition: effects of ornithine alpha-ketoglutarate. The American journal of clinical nutrition, 1994, Volume: 60, Issue:3 Topics: Adolescent; Amino Acids; Anthropometry; Body Height; Child; Female; Glutamates; Glutamine; Growth Disorders; Humans; Insulin-Like Growth Factor I; Male; Ornithine; Parenteral Nutrition, Total; Prealbumin; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Serum Albumin; Transferrin	1994
Immunomodulatory effects of ornithine alpha-ketoglutarate in rats with burn injuries. Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:7 Topics: Animals; Arginine; Burns; Dinoprostone; Glutamine; Luminescent Measurements; Male; Muscle, Skeletal; Neutrophils; Ornithine; Rats; Rats, Sprague-Dawley; Superoxides	1996
Ornithine-alpha-ketoglutarate (OKG) supplementation is more effective than its component salts in traumatized rats. The Journal of nutrition, 1996, Volume: 126, Issue:9 Topics: Amino Acids; Animals; Body Weight; Creatinine; Diet; Disease Models, Animal; Eating; Femoral Fractures; Food, Fortified; Glutamine; Glycine; Growth Hormone; Insulin; Ketoglutaric Acids; Male; Muscle, Skeletal; Nitrogen; Ornithine; Random Allocation; Rats; Rats, Sprague-Dawley; Urea; Wounds and Injuries	1996
Protective effects of ornithin-alpha-ketoglutarate supplementation on intestinal mucosa after orthotopic small bowel transplantation. Transplantation proceedings, 1996, Volume: 28, Issue:5 Topics: Animals; Bacterial Translocation; Food, Fortified; Intestinal Mucosa; Intestine, Small; Liver; Lymph Nodes; Male; Ornithine; Rats; Rats, Inbred Lew; Spleen; Transplantation, Isogeneic; Weight Gain	1996
Enteral administration of ornithine alpha-ketoglutarate or arginine alpha-ketoglutarate: a comparative study of their effects on glutamine pools in burn-injured rats. Critical care medicine, 1997, Volume: 25, Issue:2 Topics: Amino Acids; Animals; Arginine; Body Weight; Burns; Enteral Nutrition; Glutamine; Ketoglutaric Acids; Liver; Male; Ornithine; Rats; Rats, Wistar	1997
Effect of oral supplementation of ornithine-alpha-ketoglutarate on the intestinal barrier after orthotopic small bowel transplantation. Transplantation, 1997, Mar-15, Volume: 63, Issue:5 Topics: Animals; Bacterial Translocation; Body Weight; DNA; Eating; Escherichia coli; Food, Formulated; Intestinal Mucosa; Intestine, Small; Klebsiella; Male; Ornithine; Rats; Rats, Inbred Lew	1997
Enteral supplementation with ornithine alpha ketoglutarate improves the early adaptive response to resection. Gut, 1997, Volume: 40, Issue:1 Topics: Adaptation, Biological; Animals; Blotting, Northern; Caseins; Enteral Nutrition; Food, Fortified; Hyperplasia; Ileum; Jejunostomy; Male; Ornithine; Postoperative Period; Protein Hydrolysates; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine; Sucrase	1997
Ornithine alpha-ketoglutarate modulates tissue protein metabolism in burn-injured rats. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1 Topics: Animals; Burns; Enteral Nutrition; Glutamine; Jejunum; Liver; Male; Methylhistidines; Muscle, Skeletal; Myofibrils; Organ Specificity; Ornithine; Protein Biosynthesis; Proteins; Rats; Rats, Wistar; Regression Analysis; Time Factors	1997
Low glutamine concentrations induce phenotypical and functional differentiation of U937 myelomonocytic cells. The Journal of nutrition, 1997, Volume: 127, Issue:11 Topics: Antibodies, Monoclonal; Antigens, Surface; Base Sequence; Blotting, Northern; Cell Differentiation; Cell Division; Cell Line; DNA Primers; Dose-Response Relationship, Drug; Escherichia coli; Flow Cytometry; Glutamine; Histiocytes; Humans; Leukemia, Myelomonocytic, Acute; Microspheres; Monocytes; Ornithine; Phagocytosis; Phenotype; Receptors, IgE; Receptors, IgG; Time Factors	1997
Preventive administration of ornithine alpha-ketoglutarate improves intestinal mucosal repair after transient ischemia in rats. Critical care medicine, 1998, Volume: 26, Issue:1 Topics: Aminopeptidases; Animals; Cell Division; Disease Models, Animal; Enteral Nutrition; Intestinal Mucosa; Intestine, Small; Male; Mesenteric Vascular Occlusion; Ornithine; Polyamines; Rats; Rats, Wistar; Reperfusion Injury; Sucrase; Wound Healing	1998
Anorexia of aging. The American journal of clinical nutrition, 1998, Volume: 68, Issue:3 Topics: Aged; Aging; Dose-Response Relationship, Drug; Humans; Hypoglycemia; Ornithine	1998
Enteral ornithine alpha-ketoglutarate enhances intestinal adaptation to massive resection in rats. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:11 Topics: Adaptation, Physiological; Amino Acids; Animals; Enteral Nutrition; Intestinal Mucosa; Intestine, Small; Male; Muscles; Ornithine; Proteins; Rats; Rats, Wistar	1998
Ornithine alpha-ketoglutarate counteracts the decrease of liver cytochrome P-450 content in burned rats. Nutrition (Burbank, Los Angeles County, Calif.), 1999, Volume: 15, Issue:5 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Burns; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Energy Intake; Male; Microsomes, Liver; Ornithine; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley	1999
Phagocyte functions in stressed rats: comparison of modulation by glutamine, arginine and ornithine 2-oxoglutarate. Clinical science (London, England : 1979), 1999, Volume: 97, Issue:1 Topics: Amino Acids; Animals; Arginine; Glutamine; Leukocytes; Macrophages; Male; Neutrophils; Ornithine; Phagocytes; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	1999
Modulation of immune response with ornithine A-ketoglutarate in burn injury: an arginine or glutamine dependency? Nutrition (Burbank, Los Angeles County, Calif.), 1999, Volume: 15, Issue:10 Topics: Animals; Arginine; Body Weight; Burns; Glutamine; Immunity; Jejunum; Male; Muscle, Skeletal; Nitrogen; Organ Size; Ornithine; Rats; Rats, Wistar; Thymus Gland	1999
Amino acid nutrition and immune function in tumour-bearing rats: a comparison of glutamine-, arginine- and ornithine 2-oxoglutarate-supplemented diets. Clinical science (London, England : 1979), 1999, Volume: 97, Issue:6 Topics: Analysis of Variance; Animals; Arginine; Cytokines; Cytotoxicity Tests, Immunologic; Enzyme Inhibitors; Female; Fluorescent Antibody Technique, Indirect; Glutamine; Interferon-gamma; Isothiuronium; Killer Cells, Natural; Liver Neoplasms, Experimental; Lymphocyte Activation; Macrophages, Peritoneal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Ornithine; Rats; Rats, Inbred BUF; Receptors, Interleukin-2; T-Lymphocytes; Tumor Necrosis Factor-alpha	1999
Ornithine alpha-ketoglutarate and creatine effects on growth and plasma metabolites of nursery pigs. Journal of animal science, 2000, Volume: 78, Issue:4 Topics: Animal Feed; Animals; Blood Glucose; Blood Urea Nitrogen; Creatine; Dietary Supplements; Fatty Acids, Nonesterified; Ornithine; Swine; Weaning; Weight Gain	2000
Involvement of glutamine, arginine, and polyamines in the action of ornithine alpha-ketoglutarate on macrophage functions in stressed rats. Journal of leukocyte biology, 2000, Volume: 67, Issue:6 Topics: Animals; Arginine; Dietary Supplements; Enzyme Inhibitors; Glutamine; Macrophages; Male; Nitric Oxide; Ornithine; Polyamines; Rats; Rats, Sprague-Dawley; Stress, Physiological; Tumor Necrosis Factor-alpha	2000
Bacterial dissemination and metabolic changes in rats induced by endotoxemia following intestinal E. coli overgrowth are reduced by ornithine alpha-ketoglutarate administration. The Journal of nutrition, 2000, Volume: 130, Issue:12 Topics: Animals; Bacterial Translocation; Endotoxemia; Enteral Nutrition; Escherichia coli; Escherichia coli Infections; Glycine; Intestinal Mucosa; Jejunum; Lipopolysaccharides; Liver; Lymph Nodes; Male; Mesentery; Methylhistidines; Muscles; Nitrogen; Ornithine; Rats; Rats, Wistar; Spleen	2000
Glutamine supplementation promotes anaplerosis but not oxidative energy delivery in human skeletal muscle. American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:4 Topics: Adult; Amino Acids; Bicycling; Citric Acid Cycle; Energy Metabolism; Glutamine; Humans; Male; Muscle, Skeletal; Ornithine; Oxidation-Reduction; Phosphocreatine	2001
Effects of ornithine 2-oxoglutarate on neutrophils in stressed rats: evidence for the involvement of nitric oxide and polyamines. Clinical science (London, England : 1979), 2002, Volume: 102, Issue:3 Topics: Animals; Arginine; Chemotaxis, Leukocyte; Dexamethasone; Eflornithine; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamine; Hydrogen Peroxide; Isothiuronium; Male; Methionine Sulfoximine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Rats, Sprague-Dawley; Respiratory Burst; Stress, Psychological	2002
[Different therapeutic approaches for chronic diffuse liver lesions using ornicetil, lactulose, etimizol and corinfar]. Likars'ka sprava, 2002, Issue:2 Topics: Etimizol; Hepatic Encephalopathy; Hepatitis, Chronic; Humans; Lactulose; Liver Cirrhosis; Liver Diseases; Middle Aged; Nifedipine; Ornithine; Treatment Outcome	2002
Effects of ornithine alpha-ketoglutarate on circulatory antioxidants and lipid peroxidation products in ammonium acetate treated rats. Annals of nutrition & metabolism, 2002, Volume: 46, Issue:3-4 Topics: Acetates; Analysis of Variance; Animals; Antioxidants; Ascorbic Acid; Hyperammonemia; Lipid Peroxidation; Lipids; Liver; Nitrogen; Ornithine; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Urea; Vitamin E	2002
Effects of ornithine alpha-ketoglutarate on insulin secretion in rat pancreatic islets: implication of nitric oxide synthase and glutamine synthetase pathways. The British journal of nutrition, 2003, Volume: 89, Issue:2 Topics: Animals; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methionine Sulfoximine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar; Signal Transduction; Stimulation, Chemical	2003
In vivo induction of insulin secretion by ornithine alpha-ketoglutarate: involvement of nitric oxide and glutamine. Metabolism: clinical and experimental, 2003, Volume: 52, Issue:3 Topics: Animals; Arginine; Blood Glucose; Enzyme Inhibitors; Glucose; Glutamate-Ammonia Ligase; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methionine Sulfoximine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar	2003
Metabolic adaptations in higher animals. VIII. Effect of diet on ornithine-alpha-ketoglutarate transaminase. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 112 Topics: Animals; Caseins; Diet; Ketoglutaric Acids; Ornithine; Transaminases	1963
Ornithine alpha-ketoglutarate supplementation influences motor activity in healthy rats. Clinical nutrition (Edinburgh, Scotland), 2004, Volume: 23, Issue:4 Topics: Amino Acids; Animals; Behavior, Animal; Dietary Supplements; Energy Intake; Male; Maze Learning; Motor Activity; Ornithine; Random Allocation; Rats; Rats, Wistar	2004
Dose dependency of the effect of ornithine alpha-ketoglutarate on tissue glutamine concentrations and hypercatabolic response in endotoxaemic rats. The British journal of nutrition, 2004, Volume: 92, Issue:4 Topics: Amino Acids; Analysis of Variance; Animals; Dietary Supplements; Dose-Response Relationship, Drug; Endotoxemia; Glutamine; Lipopolysaccharides; Liver; Male; Methylhistidines; Nitrogen; Organ Size; Ornithine; Rats; Rats, Wistar	2004
Does dietary ornithine alpha-ketoglutarate supplementation protect the liver against ischemia-reperfusion injury? Clinical nutrition (Edinburgh, Scotland), 2005, Volume: 24, Issue:3 Topics: Animals; Enzyme Inhibitors; Glutamic Acid; In Vitro Techniques; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ornithine; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury	2005
Pretreatment of starved rats with ornithine alpha-ketoglutarate: effects on hepatic mRNA levels and plasma concentrations of three liver-secreted proteins. Nutrition (Burbank, Los Angeles County, Calif.), 2005, Volume: 21, Issue:6 Topics: Albumins; Analysis of Variance; Animals; Disease Models, Animal; Liver; Male; Ornithine; Prealbumin; Protein Biosynthesis; Random Allocation; Rats; Rats, Wistar; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; RNA, Messenger; Starvation	2005
Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state. Metabolism: clinical and experimental, 2005, Volume: 54, Issue:8 Topics: Amino Acids, Branched-Chain; Animals; Arginine; Citrulline; Glutamic Acid; Intestinal Absorption; Intestinal Mucosa; Keto Acids; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Proline; Rats; Rats, Wistar	2005
Ornithine alpha-ketoglutarate increases mineralization and mechanical properties of tibia in turkeys. Bone, 2006, Volume: 39, Issue:1 Topics: Amino Acids; Animals; Biomechanical Phenomena; Bone Density; Female; Ornithine; Random Allocation; Tibia; Turkeys	2006
Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats? Metabolism: clinical and experimental, 2007, Volume: 56, Issue:1 Topics: Animals; Arginine; Citrulline; Glutamic Acid; Intestinal Mucosa; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Random Allocation; Rats; Rats, Wistar	2007
Effect of ornithine alpha-ketoglutarate on glutamine pools in burn injury: evidence of component interaction. Intensive care medicine, 2007, Volume: 33, Issue:3 Topics: Amino Acids; Analysis of Variance; Animals; Burns; Drug Combinations; Drug Synergism; Enteral Nutrition; Glutamine; Intestinal Mucosa; Ketoglutaric Acids; Liver; Male; Muscle, Skeletal; Ornithine; Random Allocation; Rats; Rats, Wistar; Tissue Distribution	2007
Effects of ornithine alpha-ketoglutarate on protein metabolism in Yoshida sarcoma-bearing rats. Clinical nutrition (Edinburgh, Scotland), 2007, Volume: 26, Issue:5 Topics: Animals; Male; Methylhistidines; Muscle, Skeletal; Muscular Atrophy; Ornithine; Protein Biosynthesis; Proteins; Random Allocation; Rats; Rats, Wistar; Sarcoma, Experimental	2007
Ornithine alpha-ketoglutarate: could it be a new therapeutic option for sarcopenia? The journal of nutrition, health & aging, 2010, Volume: 14, Issue:7 Topics: Aged; Amino Acids; Anabolic Agents; Human Growth Hormone; Humans; Insulin; Insulin Secretion; Muscle Proteins; Muscle, Skeletal; Ornithine; Peptide Hormones; Sarcopenia	2010
Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. Acta cirurgica brasileira, 2011, Volume: 26 Suppl 1 Topics: Animals; Calcium Carbonate; Disease Models, Animal; Intestinal Diseases; Intestine, Small; Ischemia; Lactic Acid; Ligation; Ornithine; Oxidative Stress; Pyruvic Acid; Random Allocation; Rats; Reperfusion Injury; Time Factors; Treatment Outcome	2011
Ornithine alpha-ketoglutarate modulates the levels of antioxidants and lipid peroxidation products in ammonium acetate treated rats. Indian journal of biochemistry & biophysics, 2002, Volume: 39, Issue:6 Topics: Acetates; Animals; Antioxidants; Fatty Acids, Nonesterified; Free Radicals; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Mitochondria; Models, Biological; Ornithine; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances	2002
Glutamine and ornithine alpha-ketoglutarate supplementation on malate dehydrogenases expression in hepatectomized rats. Acta cirurgica brasileira, 2014, Volume: 29, Issue:6 Topics: Animals; Gene Expression; Glutamine; Hepatectomy; Liver Regeneration; Malate Dehydrogenase; Male; Models, Animal; Ornithine; Random Allocation; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reference Values; Reproducibility of Results; Time Factors; Up-Regulation	2014
Effects of ornithine α-ketoglutarate on growth performance and gut microbiota in a chronic oxidative stress pig model induced by d-galactose. Food & function, 2020, Jan-29, Volume: 11, Issue:1 Topics: Amino Acids; Animals; Galactose; Gastrointestinal Microbiome; Glutathione Peroxidase; Malondialdehyde; Ornithine; Oxidative Stress; Superoxide Dismutase; Swine	2020