orlistat and acetamide

orlistat has been researched along with acetamide* in 1 studies

Other Studies

1 other study(ies) available for orlistat and acetamide

ArticleYear
Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors.
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    A series of twenty four 2-(carbazol-3-yl)-2-oxoacetamide analogues were synthesized, characterized and evaluated for their pancreatic lipase (PL) inhibitory activity. Porcine PL was used against 4-nitrophenyl butyrate (method A) and tributyrin (methods B and C) as substrates during the PL inhibition assay. Compounds 7e, 7f and 7p exhibited potential PL inhibitory activity (IC

    Topics: Acetamides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lipase; Models, Molecular; Molecular Structure; Pancreas; Structure-Activity Relationship

2017