organophosphonates has been researched along with ym 529 in 1 studies
Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (ym 529) | Trials (ym 529) | Recent Studies (post-2010) (ym 529) |
---|---|---|---|---|---|
9,968 | 880 | 3,596 | 140 | 23 | 71 |
Protein | Taxonomy | organophosphonates (IC50) | ym 529 (IC50) |
---|---|---|---|
Geranylgeranyl pyrophosphate synthase | Homo sapiens (human) | 0.67 | |
Farnesyl pyrophosphate synthase | Homo sapiens (human) | 0.0026 | |
Farnesyl diphosphate synthase | Escherichia coli K-12 | 1.1 | |
Geranylgeranyl pyrophosphate synthase | Saccharomyces cerevisiae S288C | 0.34 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Barnett, BL; Deprèle, S; Ebetino, FH; Evdokimov, A; Hogan, JM; Kashemirov, BA; McKenna, CE | 1 |
1 other study(ies) available for organophosphonates and ym 529
Article | Year |
---|---|
Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies.
Topics: Algorithms; Binding Sites; Bone Density Conservation Agents; Carcinoma; Computer Simulation; Crystallography, X-Ray; Diphosphonates; Enzyme Inhibitors; Etidronic Acid; Farnesyltranstransferase; Humans; Imidazoles; Inhibitory Concentration 50; Magnesium; Models, Chemical; Organophosphonates; Pyridines; Risedronic Acid; Stereoisomerism; Structure-Activity Relationship; Zoledronic Acid | 2008 |