Page last updated: 2024-09-05

organophosphonates and verapamil

organophosphonates has been researched along with verapamil in 3 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(verapamil)
Trials
(verapamil)
Recent Studies (post-2010) (verapamil)
9,9688803,59617,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Annaert, P; Augustijns, P; de Clercq, E; Kinget, R; Naesens, L; Tukker, JJ; van Den Mooter, G; van Gelder, J1
Da, SL; Feng, YQ; He, HB; Hu, ZX; Qu, L1
Chapy, H; Maeng, HJ; Pang, KS; Zaman, S1

Other Studies

3 other study(ies) available for organophosphonates and verapamil

ArticleYear
In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil.
    Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:8

    Topics: Adenine; Animals; Antiviral Agents; Intestinal Absorption; Male; Organophosphonates; Prodrugs; Rats; Rats, Wistar; Verapamil

2000
High-performance liquid chromatography of some basic drugs on a n-octadecylphosphonic acid modified magnesia-zirconia stationary phase.
    Journal of separation science, 2005, Volume: 28, Issue:13

    Topics: Chlorpromazine; Doxepin; Drug Stability; Hydrogen-Ion Concentration; Indicators and Reagents; Magnesium Oxide; Organic Chemicals; Organophosphonates; Pharmaceutical Preparations; Verapamil; Zirconium

2005
Effects of 1α,25-dihydroxyvitamin D3 on transport and metabolism of adefovir dipivoxil and its metabolites in Caco-2 cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jun-14, Volume: 46, Issue:3

    Topics: Adenine; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cells, Cultured; Drug Interactions; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organophosphonates; Permeability; Verapamil; Vitamin D

2012