Compounds > organophosphonates
Page last updated: 2024-09-05

organophosphonates and topotecan

organophosphonates has been researched along with topotecan in 3 studies

Compound Research Comparison

Studies
(organophosphonates)		Trials
(organophosphonates)		Recent Studies (post-2010)
(organophosphonates)		Studies
(topotecan)		Trials
(topotecan)		Recent Studies (post-2010) (topotecan)
9,9688803,5962,392626792

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)topotecan (IC50)
Cytochrome P450 3A4Homo sapiens (human)1.5211
DNA topoisomerase 1Homo sapiens (human)0.8525
DNA topoisomerase 2-alphaHomo sapiens (human)0.605
DNA topoisomerase 2-betaHomo sapiens (human)0.605
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.06
Multidrug and toxin extrusion protein 2Homo sapiens (human)8.6
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.17

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burris, HA; Eckardt, JR; Fields, S; O'Rourke, T; Rodriguez, GI; Rothenberg, ML; Weiss, GR1
Hou, J; Major, EO1
Kondo, S; Kondo, Y1

Reviews

1 review(s) available for organophosphonates and topotecan

ArticleYear
New anticancer agents.
    Cancer chemotherapy and biological response modifiers, 1994, Volume: 15

    Topics: Adenine; Animals; Antineoplastic Agents; Camptothecin; Deoxycytidine; Gemcitabine; Humans; Imides; Indoles; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pyridines; Topotecan; Vinblastine; Vinorelbine

1994

Other Studies

2 other study(ies) available for organophosphonates and topotecan

ArticleYear
The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line.
    Journal of neurovirology, 1998, Volume: 4, Issue:4

    Topics: Anti-HIV Agents; Antiviral Agents; Brain; Cells, Cultured; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Enzyme Inhibitors; Fetus; Humans; JC Virus; Neurons; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Topotecan; Tumor Virus Infections; Virus Replication; Zidovudine

1998
American Association for Cancer Research--97th annual meeting.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:6

    Topics: Adenine; Animals; Antineoplastic Agents; Benzoquinones; Glioblastoma; HSP90 Heat-Shock Proteins; Humans; Indoles; Janus Kinase 2; Lactams, Macrocyclic; Neoplasms, Experimental; Organophosphonates; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Topotecan; Tyrphostins

2006