organophosphonates has been researched along with succinyl phosphonate in 10 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (succinyl phosphonate) | Trials (succinyl phosphonate) | Recent Studies (post-2010) (succinyl phosphonate) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 10 | 0 | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biryukov, AI; Bunik, VI; Khomutov, RM; Khurs, EN; Zhukov, YN | 1 |
| Bunik, VI; Cooper, AJ; Denton, TT; Gibson, GE; Thompson, CM; Xu, H | 1 |
| Araújo, WL; Bunik, VI; Fernie, AR; Nunes-Nesi, A; Trenkamp, S | 1 |
| Bunik, VI; Kahlert, S; Reiser, G; Zündorf, G | 1 |
| Bunik, VI; Kabysheva, MS; Klimuk, EI; Pinelis, VG; Storozhevykh, TP | 1 |
| Araújo, WL; Bettendorff, L; Bunik, VI; Fernie, AR; Strokina, AA; Trofimova, LK | 1 |
| Banerjee, K; Chen, HL; Cho, S; Chu, CT; Denton, TT; Frank, DE; Gibson, GE; Jiang, JF; Kagan, VE; Munshi, S; Tyurina, YY; Xu, H; Yang, J | 1 |
| Araujo, WL; Bettendorff, L; Bunik, VI; Daloso, D; Fernie, AR; Gaunitz, F; Grabarska, A; Juszczak, M; Meixensberger, J; Mkrtchyan, G; Oppermann, H; Rzeski, W; Stepulak, A | 1 |
| Bettendorff, L; Bunik, V; Graf, A; Mkrtchyan, G | 1 |
| Alzari, PM; Bellinzoni, M; Boyko, A; Bunik, VI; Wagner, T | 1 |
10 other study(ies) available for organophosphonates and succinyl phosphonate
| Article | Year |
|---|---|
Succinyl phosphonate inhibits alpha-ketoglutarate oxidative decarboxylation, catalyzed by alpha-ketoglutarate dehydrogenase complexes from E. coli and pigeon breast muscle.
Topics: Animals; Columbidae; Decarboxylation; Enzyme Inhibitors; Escherichia coli; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Muscle, Skeletal; Organophosphonates; Oxidation-Reduction; Succinates | 1996 |
Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain; Cattle; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Humans; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Organophosphonates; Phosphites; Rabbits; Rats; Substrate Specificity; Succinates; Swine | 2005 |
Inhibition of 2-oxoglutarate dehydrogenase in potato tuber suggests the enzyme is limiting for respiration and confirms its importance in nitrogen assimilation,.
Topics: Carbon Dioxide; Enzyme Inhibitors; Esters; Ketoglutarate Dehydrogenase Complex; Mitochondria; Nitrogen; Organophosphonates; Oxygen; Plant Proteins; Plant Tubers; Solanum tuberosum; Succinates | 2008 |
alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ.
Topics: Animals; Animals, Newborn; Cells, Cultured; Complex Mixtures; DNA; Dose-Response Relationship, Drug; Drug Interactions; Ethidium; Hippocampus; Ketoglutarate Dehydrogenase Complex; Membrane Potential, Mitochondrial; Neurons; Organophosphonates; Rats; Reactive Oxygen Species; Succinates; Time Factors | 2009 |
Phosphono analogues of 2-oxoglutarate protect cerebellar granule neurons upon glutamate excitotoxicity.
Topics: Animals; Apoptosis; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytoplasm; Dose-Response Relationship, Drug; Glutamates; Ketoglutarate Dehydrogenase Complex; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Neurons; Organophosphonates; Rats; Rats, Wistar; Succinates | 2009 |
Consequences of the α-ketoglutarate dehydrogenase inhibition for neuronal metabolism and survival: implications for neurodegenerative diseases.
Topics: Animals; Carbohydrates; Cells, Cultured; Citric Acid Cycle; Enzyme Inhibitors; Ketoglutarate Dehydrogenase Complex; Metabolome; Mitochondria; Models, Biological; Neurodegenerative Diseases; Neurons; Organophosphonates; Oxidation-Reduction; Rats; Succinates | 2012 |
Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease.
Topics: Alzheimer Disease; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Intracellular Fluid; Ketoglutarate Dehydrogenase Complex; Mitochondria; Organophosphonates; Signal Transduction; Succinates | 2016 |
Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner.
Topics: Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Ketoglutarate Dehydrogenase Complex; Neoplasms; Organophosphonates; Succinates | 2016 |
Cellular thiamine status is coupled to function of mitochondrial 2-oxoglutarate dehydrogenase.
Topics: Animals; Cerebral Cortex; Cytoplasm; Glutamic Acid; Homeostasis; Ketoglutarate Dehydrogenase Complex; Mice; Mitochondria; Organophosphonates; Succinates; Thiamine; Thiamine Pyrophosphate | 2016 |
Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts.
Topics: Catalytic Domain; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Kinetics; Mycobacterium; Organophosphonates; Oxidoreductases; Protein Binding; Succinates; Thiamine Pyrophosphate | 2019 |