Page last updated: 2024-09-05

organophosphonates and stavudine

organophosphonates has been researched along with stavudine in 98 studies

Compound Research Comparison

Studies (organophosphonates)	Trials (organophosphonates)	Recent Studies (post-2010) (organophosphonates)	Studies (stavudine)	Trials (stavudine)	Recent Studies (post-2010) (stavudine)
9,968	880	3,596	1,899	347	357

Protein Interaction Comparison

Protein	Taxonomy	organophosphonates (IC50)	stavudine (IC50)
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1		4.83

Research

Studies (98)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (3.06)	18.2507
2000's	61 (62.24)	29.6817
2010's	34 (34.69)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R	1
Allen, SJ; Chen, MS; Cherrington, JM; Fuller, MD; Kunder, SC; Lesnikowski, Z; Mulato, AS; Schinazi, RF; Sommadossi, JP; Ussery, MA	1
Cheng, B	1
Miller, MD; Naeger, LK	1
Birkus, G; Cihlar, T; Greenwalt, DE; Hitchcock, MJ	1
Margot, NA; Miller, MD; Naeger, LK	1
Bendele, RA; Richardson, FC	1
Kang, JX; Sun, XB; Zhao, YF	1
Callens, S; Colebunders, R; De Schacht, C; Huyst, V	1
Chadapaud, S; Hittinger, G; Jolly, P; Lafeuillade, A; Lambry, V; Philip, G	1
Derse, D; Hill, SA; Lloyd, PA; McDonald, S; Wykoff, J	1
Bassetti, D; Bassetti, M; Ciravegna, BW; Di Biagio, A; Ferrazin, A; Rosso, R	1
Chapman, T; McGavin, J; Noble, S	1
Cunningham, CK; McKinney, RE	1
Boyle, BA	1
Dressier, RM; James, CW; Steinhaus, MC; Szabo, S	1
Domingo, P; Elías, MJ; Guerro, MF; Labarga, P; Llibre, JM; Palacios, R; Ruiz, MI; Santos, J; Terrón, JA	1
Cheng, AK; Coakley, DF; DeJesus, E; Gallant, JE; Lu, B; Miller, MD; Pozniak, AL; Staszewski, S; Suleiman, JM; Toole, JJ	1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M	1
Auclair, M; Capeau, J; Caron, M; Kornprobst, M; Lagathu, C; Lombès, A; Walker, UA	1
Fu, H; Jiang, YY; Ju, Y; Wu, YW; Xiao, Q; Zhao, YF	1
Havlir, DV; Ignacio, CC; Koelsch, KK; Lu, B; Margot, N; Miller, MD; Strain, MC; Wong, JK	1
Amin, J; Carr, A; Cooper, DA; McAllister, J; Winston, A	1
Giacomet, V; Martelli, L; Merlo, M; Mora, S; Sciannamblo, M; Viganò, A	1
Adam, A; Maserati, R; Schewe, CK; Wassmer, G; Weitner, L	1
Aldrovandi, GM; Beretta, S; Giacomet, V; Luraschi, P; Martelli, L; Merlo, M; Mora, S; Rombolà, G; Viganò, A	1
Manfredi, R	1
Andreoni, M; Antinori, A; Bini, T; Bonora, S; Carosi, G; Castagna, A; Di Perri, G; Landonio, S; Merli, S; Nasta, P; Perno, CF; Quirino, T; Tozzi, V; Trotta, MP; Zaccarelli, M	1
Antela, A; Domingo, P; Llibre, JM; Miralles, C; Moreno, S; Palacios, R; Pérez-Elías, MJ; Sánchez-de la Rosa, R; Santos, J	1
Cheng, A; Lu, B; Margot, NA; Miller, MD	1
Cartledge, J; Churchill, D; Fakoya, A; Hay, P; Johnson, M; Leen, C; Moyle, GJ; Murphy, M; Reilly, G; Sabin, CA; Scullard, G; Wilkins, E	1
Bogner, J; Claas, GJ; Goebel, FD; Jülg, B	1
Anastos, K; Cohen, M; Cole, S; Hessol, NA; Justman, J; Kaplan, RC; Lu, D; Shi, Q; Tien, PC; Vigen, C; Young, M	1
Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X	1
Borgonovo, S; Brambilla, P; Cafarelli, L; Giacomet, V; Mora, S; Viganò, A; Zamproni, I; Zuccotti, G	1
Arnaiz, JA; Blanco, JL; de Lazzari, E; Garrabou, G; Gatell, JM; Laguno, M; Larrousse, M; Leon, A; Lonca, M; López, S; Mallolas, J; Martinez, E; Milinkovic, A; Miró, O; Vidal, S	1
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A	1
Chantratitra, W; Kiertiburanakul, S; Manosuthi, W; Sungkanuparph, S	1
Cossarizza, A; Dentone, C; Di Biagio, A; Esposito, R; Ferraresi, R; Mussini, C; Nasi, M; Nemes, E; Pinti, M; Repetto, E; Rosso, R; Viscoli, C	1
Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S	1
Ananworanich, J; Côté, HC; Hill, A; Hirschel, B; Jupimai, T; Kerr, SJ; Laopraynak, N; Nuesch, R; Ruxrungtham, K; Saenawat, S	1
Guedj, R	1
Fox, M; Long, L; Rosen, S; Sanne, I	1
Borroto-Esoda, K; Feng, JY; Goodman, D; Kutty, N; Ly, JK; Margot, NA; Miller, MD; Myrick, F; Svarovskaia, ES; Wang, R; White, KL	1
Cotter, BR; Currier, JS; Dubé, MP; Fichtenbaum, CJ; Gerschenson, M; Komarow, L; Mitchell, CK; Murphy, RL; Parker, RA; Squires, K; Stein, JH; Torriani, FJ	1
Chen, SS; Cheng, AK; DeJesus, E; Enejosa, JV; Gallant, JE; Pozniak, AL; Winston, JA	1
Atté, EF; Rasschaert, F; Reid, T; van Griensven, J; Zachariah, R	1
Portilla, J	1
Moreno, V; Valencia, ME	1
Belsey, E; Berzins, B; Chen, D; Choi, J; da Silva, B; Gerschenson, M; Kim, C; Libutti, DE; McComsey, GA; Murphy, RL; Shore, J; Taiwo, B; Weinstein, J	1
Calmy, A; Ford, N; Mills, E	1
Colebunders, R; Lynen, L; van Griensven, J	1
Borroto-Esoda, K; Harris, J; Lansdon, EB; Miller, MD; O'Neal, W; Svarovskaia, ES; Wakeford, C; Waters, JM; White, KL	1
Benn, P; Cartledge, J; Edwards, SG; Linney, A; Moyle, G; Reilly, G; Ruff, C; Sabin, CA; Sauret-Jackson, V	1
Andrade, A; Eshleman, SH; Flanigan, T; Flexner, C; Gross, R; Hogg, E; Lalama, C; Mildvan, D; Reisler, R; Rosenkranz, S; Salomon, N; Santana, J; Tierney, C; Wiggins, I	1
Roehr, B	1
Ding, J; Li, C; Qian, N; Qiao, R; Zhao, Y	1
Bangsberg, DR	1
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW	1
Alvarez, K; Balzarini, J; Barral, K; Canard, B; De Michelis, C; Neyts, J; Priet, S; Sire, J	1
Bender, MA; Flanigan, T; Freedberg, KA; Kumarasamy, N; Lu, Z; Mayer, KH; Schackman, BR; Scott, CA; Walensky, RP; Wang, B	1
Altice, FL; Springer, SA	1
Asboe, D; Dunn, D; Fearnhill, E; Gazzard, B; Pillay, D; Pozniak, A; Price, H	1
Freedberg, KA; Loubiere, S; Meiners, C; Sloan, C; Yazdanpanah, Y	1
Baba, M; Hamasaki, T; Haraguchi, K; Ishizaki, N; Kubota, Y; Tanaka, H	1
Bénet, T; Billioud, C; Boibieux, A; Brochier, C; Chevallier, M; Cotte, L; Ferry, T; Miailhes, P; Scoazec, JY; Vanhems, P; Zoulim, F	1
Curran, A; Ribera, E	1
Chimsuntorn, S; Lueangniyomkul, A; Mankatitham, W; Manosuthi, W; Nilkamhang, S; Sungkanuparph, S; Suntisuklappon, B; Tantanathip, P; Thongyen, S	1
Bygrave, H; Cleary, S; Ford, N; Gadot, L; Goemaere, E; Hilderbrand, K; Jouquet, G; Kranzer, K; Lee, J; Makakole, L; Trivino, L; Vlahakis, N	1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C	1
Gordon, M; Hampton, J; Johnson, B; Kuritzkes, DR; Marconi, VC; Moosa, MY; Ordonez, C; Sunpath, H; Wu, B	1
Carda-Broch, S; Casas-Breva, I; Esteve-Romero, J; Peris-Vicente, J; Rambla-Alegre, M	1
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S	1
Hansen, BE; Janssen, HL; Koëter, T; Komuta, M; Rossing, HH; Schouten, JN; Van der Ende, ME; van der Valk, M; Verheij, J	1
Crowther, NJ; Dickens, C; Dix-Peek, T; Duarte, R; Fox, MP; Ive, P; John, MA; Macphail, P; Maskew, M; Menezes, CN; Raal, F; Sanne, I; Van Amsterdam, D	1
Côté, HC; Hukezalie, KR; Thumati, NR; Wong, JM	1
Ananworanich, J; Chomchey, N; Gerschenson, M; Hongchookiat, P; Jadwattanakul, T; Kerr, SJ; Kim, JH; Mathajittiphun, P; Phanuphak, N; Phanuphak, P; Pinyakorn, S; Praihirunyakit, P; Rungrojrat, P; Shikuma, C; Teeratakulpisarn, N; Valcour, V	1
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF	1
Bedogni, G; Cococcioni, L; Fabiano, V; Giacomet, V; Mora, S; Stucchi, S; Viganò, A; Zuccotti, GV	1
Aghokeng, A; Belec, L; Bertagnolio, S; Bunupuradah, T; Burda, S; Cane, P; Cappelli, G; Charpentier, C; Dagnra, AY; de Wit, TF; Deshpande, AK; El-Katib, Z; Eshleman, SH; Fleury, HJ; Fokam, J; Ford, N; Gody, JC; Hamers, RL; Hawkins, CA; Holmes, S; Hosseinipour, MC; Jordan, MR; Kanki, PJ; Katzenstein, D; Koyalta, DD; Kumwenda, JJ; Lallemant, M; Lynen, L; Manosuthi, W; Marconi, VC; Margot, NA; Moussa, S; Ndung'u, T; Ngo-Giang-Huong, N; Nyambi, PN; Orrell, C; Peeters, M; Rhee, SY; Ruxrungtham, K; Schapiro, JM; Schuurman, R; Shafer, RW; Sigaloff, KC; Sirivichayakul, S; Smith, D; Stevens, W; Tang, MW; van Zyl, GU; Wallis, CL; Zolfo, M	1
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K	1
Gulholm, T; Jamani, S; Poynten, IM; Templeton, DJ	1
Flint, OP; Wang, F	1
Boulle, A; Chi, BH; Chimbetete, C; Egger, M; Fox, MP; Gerber, F; Gsponer, T; Hoffmann, CJ; Orrell, C; Prozesky, H; Rohr, J; Wandeler, G; Zwahlen, M	1
Brennan, AT; Fox, MP; Long, L; Maskew, M; Sanne, I; Shearer, K	1
Moyo, C; Vinikoor, MJ	1
Bloch, N; Huber, AD; Ji, J; Kirby, KA; Landau, NR; Leslie, MD; Lucas, AD; Michailidis, E; Ong, YT; Puray-Chavez, MN; Sarafianos, SG; Schultz, ML	1
Greeff, OB; Hurrell, T; Khwitshana, AK	1
Guo, F; Li, T; Lin, Q; Shao, H; Sun, P; Tian, J; Xu, Y; Yu, W; Zhou, X	1
Havens, PL; Hazra, R	1
McGuigan, C; Pertusati, F; Serpi, M	1
Arterburn, S; Castaño, E; Cheng, AK; Chuck, SL; Church, J; Deville, J; Enejosa, JV; Estripeaut, D; Gaur, A; Rathore, M; Rhee, MS; Saez-Llorens, X; White, K	1
Goryaeva, MP; Gulyaeva, SS; Minaeva, SV; Moshkovich, GF; Tichonova, EV; Varlova, LW	1

Reviews

11 review(s) available for organophosphonates and stavudine

Article	Year
Targeted therapy of human immunodeficiency virus-related disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10 Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine	1991
Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out? Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:3 Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Drug Resistance, Microbial; HIV-1; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Tenofovir; Zidovudine	2001
Tenofovir disoproxil fumarate. Drugs, 2003, Volume: 63, Issue:15 Topics: Adenine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Treatment Outcome	2003
Newer treatments for HIV in children. Current opinion in pediatrics, 2004, Volume: 16, Issue:1 Topics: Adenine; Anti-Bacterial Agents; Anti-HIV Agents; Child; Deoxycytidine; Didanosine; Drug Therapy, Combination; Emtricitabine; Enfuvirtide; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Peptide Fragments; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir	2004
The continuing evolution of HIV therapy. The AIDS reader, 2003, Volume: 13, Issue:12 Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2003
Tenofovir-related nephrotoxicity: case report and review of the literature. Pharmacotherapy, 2004, Volume: 24, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Anti-HIV Agents; Clinical Chemistry Tests; Fanconi Syndrome; Female; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Time Factors; Treatment Outcome	2004
[AIDS: ethics and scientific investigation on human beings]. Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Anti-HIV Agents; Azathioprine; Clinical Trials as Topic; Congresses as Topic; Cyclosporine; Developing Countries; Ditiocarb; Double-Blind Method; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ethics Committees, Research; Human Experimentation; Humans; Informed Consent; Mass Media; Oligodeoxyribonucleotides, Antisense; Organophosphonates; Practice Guidelines as Topic; Stavudine; Tenofovir; Thionucleotides	2008
[Tenofovir as a strategy to avoid or limit adverse effects]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8 Topics: Adenine; Anemia; Anti-HIV Agents; Antimetabolites; Clinical Trials as Topic; DNA, Mitochondrial; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Glucose Metabolism Disorders; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Multicenter Studies as Topic; Organophosphonates; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine	2008
Economic evaluation of ART in resource-limited countries. Current opinion in HIV and AIDS, 2010, Volume: 5, Issue:3 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cost-Benefit Analysis; Developing Countries; Drug Monitoring; Health Care Costs; HIV Infections; Humans; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Viral Load	2010
From old to new nucleoside reverse transcriptase inhibitors: changes in body fat composition, metabolic parameters and mitochondrial toxicity after the switch from thymidine analogs to tenofovir or abacavir. Expert opinion on drug safety, 2011, Volume: 10, Issue:3 Topics: Adenine; Adipose Tissue; Body Composition; Dideoxynucleosides; Drug Substitution; Humans; Metabolism; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zidovudine	2011
Antiretrovirals for HIV Exposure Prophylaxis. Current medicinal chemistry, 2012, Volume: 19, Issue:35 Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine	2012

Trials

21 trial(s) available for organophosphonates and stavudine

Article	Year
Evolution of lipid abnormalities in patients switched from stavudine- to tenofovir-containing regimens. Journal of acquired immune deficiency syndromes (1999), 2003, Aug-01, Volume: 33, Issue:4 Topics: Adenine; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Double-Blind Method; Female; HIV Infections; Humans; Lipids; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; RNA, Viral; Stavudine; Tenofovir	2003
Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA, 2004, Jul-14, Volume: 292, Issue:2 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Oxazines; Prospective Studies; Stavudine; Tenofovir; Viral Load	2004
Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children. Antiviral therapy, 2005, Volume: 10, Issue:8 Topics: Adenine; Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Cyclopropanes; Dyslipidemias; Female; HIV Infections; HIV-1; Humans; Lipids; Male; Organophosphonates; Oxazines; Protease Inhibitors; Stavudine; Tenofovir; Treatment Outcome; Viral Load	2005
Resistance development over 144 weeks in treatment-naive patients receiving tenofovir disoproxil fumarate or stavudine with lamivudine and efavirenz in Study 903. HIV medicine, 2006, Volume: 7, Issue:7 Topics: Adenine; Alkynes; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Treatment Outcome	2006
A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy. AIDS (London, England), 2006, Oct-24, Volume: 20, Issue:16 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Biomarkers; Body Fat Distribution; Dideoxynucleosides; Female; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lipids; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2006
Metabolic and anthropometric changes one year after switching from didanosine/stavudine to tenofovir in HIV-infected patients. European journal of medical research, 2007, Feb-26, Volume: 12, Issue:2 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Didanosine; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Hemoglobins; HIV Infections; Humans; Lactic Acid; Male; Middle Aged; Organophosphonates; Phosphates; Skinfold Thickness; Stavudine; Tenofovir; Treatment Outcome; Triglycerides; Uric Acid; Viral Load	2007
Normalization of fat accrual in lipoatrophic, HIV-infected children switched from stavudine to tenofovir and from protease inhibitor to efavirenz. Antiviral therapy, 2007, Volume: 12, Issue:3 Topics: Absorptiometry, Photon; Adenine; Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atrophy; Benzoxazines; Body Composition; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Female; HIV Protease Inhibitors; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Italy; Male; Organophosphonates; Prospective Studies; Protease Inhibitors; Stavudine; Tenofovir; Time Factors; Treatment Outcome; Viral Load	2007
The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients. Antiviral therapy, 2007, Volume: 12, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Body Composition; Cholesterol; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Lipodystrophy; Male; Middle Aged; Mitochondria; Organophosphonates; Oxygen Consumption; Stavudine; Tenofovir; Treatment Outcome; Triglycerides	2007
Effects of the change from Stavudine to tenofovir in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy: studies on mitochondrial toxicity and thymic function. The Pediatric infectious disease journal, 2008, Volume: 27, Issue:1 Topics: Adenine; Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood Glucose; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Child; DNA, Mitochondrial; Female; HIV Infections; Humans; Lipids; Male; Mitochondria; Organophosphonates; Stavudine; Tenofovir; Thymus Gland; Viral Load	2008
Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy. The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:6 Topics: Absorptiometry, Photon; Adenine; Adult; Anti-HIV Agents; Body Fat Distribution; Didanosine; DNA, Mitochondrial; HIV Infections; Humans; Lamivudine; Lipids; Liver Function Tests; Organophosphonates; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Tenofovir; Thailand	2008
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s. Journal of the American College of Cardiology, 2008, Aug-12, Volume: 52, Issue:7 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine	2008
The 3-year renal safety of a tenofovir disoproxil fumarate vs. a thymidine analogue-containing regimen in antiretroviral-naive patients. AIDS (London, England), 2008, Oct-18, Volume: 22, Issue:16 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Phosphorus; Proteinuria; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Young Adult; Zidovudine	2008
Improvements in cheek volume in lipoatrophic individuals switching away from thymidine nucleoside reverse transcriptase inhibitors. HIV medicine, 2009, Volume: 10, Issue:6 Topics: Absorptiometry, Photon; Adenine; Adult; Aged; Body Composition; Cheek; Dideoxynucleosides; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Middle Aged; Organophosphonates; Quality of Life; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2009
Modified directly observed antiretroviral therapy compared with self-administered therapy in treatment-naive HIV-1-infected patients: a randomized trial. Archives of internal medicine, 2009, Jul-13, Volume: 169, Issue:13 Topics: Adenine; Administration, Oral; Adolescent; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Dose-Response Relationship, Drug; Emtricitabine; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Retrospective Studies; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Young Adult	2009
Modified directly observed therapy to improve HIV treatment outcomes: little impact with potent, once-daily therapy in unselected antiretroviral-naïve patients. Current HIV/AIDS reports, 2009, Volume: 6, Issue:4 Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Directly Observed Therapy; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV-1; Humans; Lopinavir; Medication Adherence; Organophosphonates; Pyrimidinones; Ritonavir; Self Administration; Stavudine; Tenofovir; Treatment Outcome	2009
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial. Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707 Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine	2009
Metabolic benefits of switching to tenofovir/lamivudine after long-term use of stavudine/lamivudine in NNRTI-based antiretroviral regimens: a prospective study. The Journal of infection, 2011, Volume: 62, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Female; HIV Infections; Humans; Lamivudine; Lipid Metabolism; Male; Middle Aged; Organophosphonates; Prospective Studies; Stavudine; Tenofovir; Treatment Outcome	2011
The early effects of stavudine compared with tenofovir on adipocyte gene expression, mitochondrial DNA copy number and metabolic parameters in South African HIV-infected patients: a randomized trial. HIV medicine, 2013, Volume: 14, Issue:4 Topics: Adenine; Adipocytes; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biomarkers; DNA Copy Number Variations; DNA, Mitochondrial; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Glucose; HIV Infections; Humans; Inflammation; Lipid Metabolism; Male; Middle Aged; Organophosphonates; Prospective Studies; Reverse Transcriptase Inhibitors; South Africa; Stavudine; Tenofovir	2013
A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine. Antiviral therapy, 2012, Volume: 17, Issue:8 Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Diet; Drug Administration Schedule; Drug Substitution; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Peripheral Nervous System Diseases; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2012
Long-term body composition and metabolic changes in HIV-infected children switched from stavudine to tenofovir and from protease inhibitors to efavirenz. European journal of pediatrics, 2013, Volume: 172, Issue:8 Topics: Absorptiometry, Photon; Adenine; Adolescent; Alkynes; Anti-Retroviral Agents; Benzoxazines; Blood Glucose; Body Composition; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Female; HIV Infections; Humans; Lamivudine; Linear Models; Lipids; Longitudinal Studies; Male; Organophosphonates; Stavudine; Tenofovir	2013
A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression. The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4 Topics: Adenine; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine	2015

Other Studies

66 other study(ies) available for organophosphonates and stavudine

Article	Year
Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5 Topics: Adenine; Antiviral Agents; HIV Reverse Transcriptase; HIV-1; Kinetics; Organophosphonates; Phosphates; Rauscher Virus; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine	1996
Update on other antivirals. PI perspective, 1996, Issue:no 18 Topics: Adenine; Antiviral Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Stavudine; Zalcitabine; Zidovudine	1996
Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors. Antiviral research, 2002, Volume: 54, Issue:1 Topics: Adenine; Anti-HIV Agents; Antigens, CD34; Cell Line; Didanosine; Dideoxynucleosides; Epithelial Cells; Hematopoietic Stem Cells; Humans; Kidney Tubules, Proximal; Liver; Muscle, Skeletal; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Tumor Cells, Cultured; Zalcitabine; Zidovudine	2002
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7 Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Catalysis; Drug Resistance, Viral; HIV Reverse Transcriptase; Mutation; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zidovudine	2002
Adefovir nephrotoxicity and mitochondrial DNA depletion. Human pathology, 2002, Volume: 33, Issue:5 Topics: Adenine; Antiviral Agents; Clinical Trials, Phase III as Topic; Cyclooxygenase Inhibitors; DNA, Mitochondrial; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Kidney Tubules; Mitochondria; Organophosphonates; Renal Insufficiency; Stavudine	2002
[Tenofovir in Study 903. Also effective and tolerable in first-line therapy]. MMW Fortschritte der Medizin, 2002, Aug-22, Volume: 144, Issue:33-34 Topics: Adenine; Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Treatment Outcome; Viral Load	2002
One-pot synthesis of hydrogen phosphonate derivatives of d4T and AZT. Chemical communications (Cambridge, England), 2002, Oct-21, Issue:20 Topics: Anti-HIV Agents; Humans; Organophosphonates; Prodrugs; Stavudine; Zidovudine	2002
New uses for tenofovir: more questions about d4T. Project Inform perspective, 2003, Issue:35 Topics: Adenine; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir	2003
Pancreatitis in an HIV-infected person on a tenofovir, didanosine and stavudine containing highly active antiretroviral treatment. The Journal of infection, 2003, Volume: 47, Issue:2 Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Interactions; Female; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Pancreatitis; Ritonavir; Stavudine; Tenofovir	2003
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors. The Journal of infectious diseases, 2003, Aug-01, Volume: 188, Issue:3 Topics: Adenine; Cell Line; Dideoxynucleosides; Human T-lymphotropic virus 1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zalcitabine; Zidovudine	2003
Fatal lactic acidosis and mimicking Guillain-Barré syndrome in an adolescent with human immunodeficiency virus infection. The Pediatric infectious disease journal, 2003, Volume: 22, Issue:7 Topics: Acidosis, Lactic; Adenine; Adolescent; Antiretroviral Therapy, Highly Active; Carbamates; Diagnosis, Differential; Didanosine; Disease Progression; Drug Therapy, Combination; Fatal Outcome; Female; Furans; Guillain-Barre Syndrome; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Organophosphonates; Organophosphorus Compounds; Risk Assessment; Severity of Illness Index; Stavudine; Sulfonamides; Tenofovir	2003
[Lipid profile and body fat--significant "side effect" of antiretroviral therapy. Tenofovir: favorable profile of adverse effects]. MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1 Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Body Composition; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Humans; Lamivudine; Lipids; Organophosphonates; Organophosphorus Compounds; Oxazines; Stavudine; Tenofovir	2003
Improvement of dyslipidemia in patients switching from stavudine to tenofovir: preliminary results. AIDS (London, England), 2004, Jul-02, Volume: 18, Issue:10 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Hyperlipidemias; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir	2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance. AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12 Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine	2004
Antiretroviral treatment. HIV infection in adults: better-defined first-line treatment. Prescrire international, 2004, Volume: 13, Issue:72 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Oligopeptides; Organophosphonates; Oxazines; Pregnancy; Pyrimidinones; Ritonavir; Stavudine; Sulfonamides; Treatment Outcome; Viral Load; Zidovudine	2004
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro. AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16 Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2004
Synthesis, in vitro anticancer evaluation, and interference with cell cycle progression of N-phosphoamino acid esters of zidovudine and stavudine. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:11 Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Organophosphonates; Phosphoamino Acids; Stavudine; Zidovudine	2004
Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine. The Journal of infectious diseases, 2005, Apr-01, Volume: 191, Issue:7 Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; DNA, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Oxazines; RNA, Viral; Stavudine; Tenofovir; Viremia	2005
The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis. HIV medicine, 2005, Volume: 6, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chi-Square Distribution; HIV Infections; Humans; Lamivudine; Male; Nelfinavir; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Assessment; Risk-Taking; Stavudine; Tenofovir; Zidovudine	2005
A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children. Journal of acquired immune deficiency syndromes (1999), 2005, Dec-01, Volume: 40, Issue:4 Topics: Absorptiometry, Photon; Adenine; Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; Child; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir	2005
Improved lipid profiles and maintenance of virologic control in heavily pretreated HIV-infected patients who switched from stavudine to tenofovir treatment. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Jan-01, Volume: 42, Issue:1 Topics: Adenine; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Lipid Metabolism; Male; Middle Aged; Organophosphonates; Retrospective Studies; Stavudine; Tenofovir	2006
Improvement of dyslipidemia during different HAART regimens: tenofovir- versus stavudine-containing antiretroviral combinations. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, May-01, Volume: 42, Issue:9 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dyslipidemias; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir	2006
Antiviral efficacy and genotypic resistance patterns of combination therapy with stavudine/tenofovir in highly active antiretroviral therapy experienced patients. Antiviral therapy, 2006, Volume: 11, Issue:2 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biological Evolution; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; RNA, Viral; Stavudine; Tenofovir; Treatment Failure; Viral Load	2006
Sustained improvement of dyslipidaemia in HAART-treated patients replacing stavudine with tenofovir. AIDS (London, England), 2006, Jun-26, Volume: 20, Issue:10 Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Dyslipidemias; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Prospective Studies; Risk Factors; Stavudine; Tenofovir	2006
Five-year data out on Viread. AIDS patient care and STDs, 2006, Volume: 20, Issue:12 Topics: Adenine; Anti-HIV Agents; Double-Blind Method; Drug Administration Schedule; HIV Infections; Humans; Organophosphonates; Randomized Controlled Trials as Topic; Stavudine; Tenofovir	2006
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of acquired immune deficiency syndromes (1999), 2007, May-01, Volume: 45, Issue:1 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black People; Cholesterol; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Fasting; Female; Hispanic or Latino; HIV Infections; HIV Protease Inhibitors; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Multivariate Analysis; Nelfinavir; Nevirapine; Organophosphonates; Ritonavir; Stavudine; Tenofovir; Triglycerides; United States; White People	2007
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine	2007
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2007
Tenofovir resistance among HIV-infected patients failing a fixed-dose combination of stavudine, lamivudine, and nevirapine in a resource-limited setting. AIDS patient care and STDs, 2007, Volume: 21, Issue:10 Topics: Adenine; Adult; Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Thailand; Treatment Outcome	2007
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement. Journal of neurovirology, 2008, Volume: 14, Issue:1 Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine	2008
Cost and cost-effectiveness of switching from stavudine to tenofovir in first-line antiretroviral regimens in South Africa. Journal of acquired immune deficiency syndromes (1999), 2008, Jul-01, Volume: 48, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Cost-Benefit Analysis; Humans; Models, Biological; Organophosphonates; Quality of Life; South Africa; Stavudine; Tenofovir	2008
The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation. Journal of acquired immune deficiency syndromes (1999), 2008, Aug-01, Volume: 48, Issue:4 Topics: Adenine; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Organophosphonates; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication	2008
Weight evolution in HIV-1 infected women in Rwanda after stavudine substitution due to lipoatrophy: comparison of zidovudine with tenofovir/abacavir. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:6 Topics: Adenine; Adult; Anti-HIV Agents; Body Weight; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Organophosphonates; Rwanda; Stavudine; Tenofovir; Treatment Outcome; Weight Loss; Zidovudine	2009
[Atazanavir-induced nephrolithiasis]. Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2 Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D, Chronic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lopinavir; Male; Nephrolithiasis; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir	2009
Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen. The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Adipose Tissue; Adult; Anti-HIV Agents; Body Fat Distribution; CD4 Lymphocyte Count; Deoxyguanosine; F2-Isoprostanes; Glutathione; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Mitochondria; Organophosphonates; Pyrimidinones; Ritonavir; Stavudine; Tenofovir; Treatment Outcome; Viral Load	2009
Rationing antiretroviral therapy in Africa--treating too few, too late. The New England journal of medicine, 2009, Apr-30, Volume: 360, Issue:18 Topics: Adenine; Africa; Anti-Retroviral Agents; CD4 Lymphocyte Count; Developing Countries; Drug Administration Schedule; Health Care Rationing; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir; Viral Load	2009
Substituting tenofovir for stavudine in resource-limited settings: there are challenges ahead. AIDS (London, England), 2009, May-15, Volume: 23, Issue:8 Topics: Adenine; Anti-HIV Agents; Developing Countries; Drug Therapy, Combination; HIV Infections; Humans; Organophosphonates; Stavudine; Tenofovir; Treatment Failure	2009
Mutations in the thumb-connection and RNase H domain of HIV type-1 reverse transcriptase of antiretroviral treatment-experienced patients. Antiviral therapy, 2009, Volume: 14, Issue:2 Topics: Adenine; Alkynes; Amino Acid Substitution; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Genetic Variation; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Ribonuclease H, Human Immunodeficiency Virus; Stavudine; Tenofovir	2009
HIV clinics are halting enrolment of new patients as funding stalls, MSF warns. BMJ (Clinical research ed.), 2009, Jul-20, Volume: 339 Topics: Adenine; Anti-HIV Agents; Developing Countries; Drug Costs; HIV Infections; Hospitals, Special; Humans; Organophosphonates; Stavudine; Tenofovir	2009
Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates. Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:17 Topics: Anti-HIV Agents; Distamycins; Molecular Structure; Organophosphonates; Spectrometry, Mass, Electrospray Ionization; Stavudine; Tandem Mass Spectrometry	2009
Synthesis and antiviral activity of boranophosphonate isosteres of AZT and d4T monophosphates. European journal of medicinal chemistry, 2010, Volume: 45, Issue:2 Topics: Animals; Antiviral Agents; Cell Line; Drug Stability; Half-Life; Humans; Organophosphonates; Stavudine; Viruses; Zidovudine	2010
Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Feb-01, Volume: 50, Issue:3 Topics: Adenine; Adult; Antifungal Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Female; HIV Infections; Humans; India; Male; Organophosphonates; Stavudine; Survival Analysis; Tenofovir; Treatment Outcome; Zidovudine	2010
DAART for human immunodeficiency virus-infected patients: Studying subjects not at risk for nonadherence and use of untested interventions. Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1 Topics: Adenine; Administration, Oral; Adolescent; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Emtricitabine; Female; Genotype; HIV Infections; HIV-1; Humans; Lopinavir; Male; Middle Aged; Organophosphonates; Patient Compliance; Pyrimidinones; Randomized Controlled Trials as Topic; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Young Adult	2010
Positive and negative drug selection pressures on the N348I connection domain mutation: new insights from in vivo data. Antiviral therapy, 2010, Volume: 15, Issue:2 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Case-Control Studies; Cyclopropanes; Databases, Genetic; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Reverse Transcriptase; HIV-1; Humans; Logistic Models; Mutation; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine	2010
Synthesis and anti-HIV-1 evaluation of phosphonates which mimic the 5'-monophosphate of 4'-branched 2',3'-didehydro-2',3'-dideoxy nucleosides. Bioorganic & medicinal chemistry, 2010, Oct-15, Volume: 18, Issue:20 Topics: Anti-HIV Agents; Cell Line; Dideoxynucleosides; HIV-1; Humans; Organophosphonates; Stavudine	2010
The role of nucleoside and nucleotide analogues in nodular regenerative hyperplasia in HIV-infected patients: a case control study. Journal of hepatology, 2011, Volume: 54, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Didanosine; Female; HIV Infections; Humans; Hyperplasia; Hypertension, Portal; Liver; Liver Regeneration; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir	2011
Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho. Journal of acquired immune deficiency syndromes (1999), 2011, Nov-01, Volume: 58, Issue:3 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Developing Countries; Female; Health Care Costs; HIV Infections; Humans; Lesotho; Male; Middle Aged; Organophosphonates; Pregnancy; Rural Population; Stavudine; Tenofovir; Zidovudine	2011
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria. BMC clinical pharmacology, 2012, Feb-27, Volume: 12 Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine	2012
High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen. AIDS (London, England), 2012, Aug-24, Volume: 26, Issue:13 Topics: Adenine; Adult; Arginine; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Viral; Female; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Lysine; Male; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; South Africa; Stavudine; Tenofovir; Treatment Failure; Viral Load	2012
Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography. The Analyst, 2012, Sep-21, Volume: 137, Issue:18 Topics: Acquired Immunodeficiency Syndrome; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chromatography, Liquid; Cyclopropanes; Drug Monitoring; Humans; Lamivudine; Organophosphonates; Stavudine; Tenofovir; Zidovudine	2012
Risk factors and outcome of HIV-associated idiopathic noncirrhotic portal hypertension. Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:9 Topics: Adenine; Adult; Anti-HIV Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Hypertension, Portal; Liver; Male; Middle Aged; Multivariate Analysis; Netherlands; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Young Adult	2012
In vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIs. PloS one, 2012, Volume: 7, Issue:11 Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Line; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA Primers; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Telomerase; Tenofovir; Zidovudine	2012
Cardiometabolic risk factors among HIV patients on antiretroviral therapy. Lipids in health and disease, 2013, Apr-10, Volume: 12 Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine	2013
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine. The Journal of infectious diseases, 2013, Jun-15, Volume: 207 Suppl 2 Topics: Adenine; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Databases, Factual; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Mutation, Missense; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Tenofovir; Zidovudine	2013
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study. PloS one, 2013, Volume: 8, Issue:5 Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine	2013
Non-occupational HIV post-exposure prophylaxis at a Sydney metropolitan sexual health clinic. Sexual health, 2013, Volume: 10, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; Australia; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; Homosexuality, Male; Humans; Male; Middle Aged; Organophosphonates; Post-Exposure Prophylaxis; Practice Guidelines as Topic; Practice Patterns, Physicians'; Risk-Taking; Stavudine; Tenofovir	2013
BMS-986001, an HIV nucleoside reverse transcriptase inhibitor, does not degrade mitochondrial DNA in long-term primary cultures of cells isolated from human kidney, muscle, and adipose tissue. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Adenine; Adipocytes; DNA Fragmentation; DNA, Mitochondrial; Epithelial Cells; Humans; Kidney Tubules, Proximal; Mitochondria; Muscle Fibers, Skeletal; Organophosphonates; Primary Cell Culture; Reverse Transcriptase Inhibitors; Stavudine; Structure-Activity Relationship; Tenofovir; Thymidine	2013
Tenofovir or zidovudine in second-line antiretroviral therapy after stavudine failure in southern Africa. Antiviral therapy, 2014, Volume: 19, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Retreatment; South Africa; Stavudine; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine	2014
Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir. Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:5 Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Female; Follow-Up Studies; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Prospective Studies; South Africa; Stavudine; Survival Analysis; Survival Rate; Tenofovir; Treatment Outcome; Viral Load; Young Adult	2014
Leveraging rapid implementation of an HIV treatment policy to reduce confounding in observational analysis of antiretroviral outcomes. Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:5 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Male; Organophosphonates; Stavudine; Tenofovir	2014
SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Adenine; Cell Line; Dideoxynucleotides; Gene Expression; Genes, Reporter; HIV Reverse Transcriptase; HIV-1; Host-Pathogen Interactions; Humans; Lamivudine; Luciferases; Monocytes; Monomeric GTP-Binding Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Tenofovir; Virus Replication; Zidovudine	2014
Assessing adherence to the 2010 antiretroviral guidelines at the antiretroviral rollout clinic in 1 military hospital, South Africa: a retrospective, cross sectional study. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2014, Jun-17, Volume: 104, Issue:7 Topics: Adenine; Adult; Anti-Retroviral Agents; Cross-Sectional Studies; Drug Monitoring; Drug Substitution; Female; Guideline Adherence; HIV Infections; Hospitals, Military; Humans; Male; Organophosphonates; Outcome Assessment, Health Care; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; South Africa; Stavudine; Tenofovir	2014
[To evaluate the changes in body composition in male human immunodeficiency virus-related lipodystrophy after different treatment regimens by dual-energy X-ray absorptiometry]. Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:8 Topics: Absorptiometry, Photon; Adenine; Anti-HIV Agents; Antiviral Agents; Body Composition; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Male; Organophosphonates; Stavudine; Tenofovir; Zidovudine	2014
Commentary: The place of tenofovir disoproxil fumarate in pediatric antiretroviral therapy. The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Stavudine; Zidovudine	2015
Symmetrical diamidate prodrugs of nucleotide analogues for drug delivery. Current protocols in nucleic acid chemistry, 2015, Mar-09, Volume: 60 Topics: Adenine; Antiviral Agents; Drug Delivery Systems; Humans; Nucleotides; Organophosphonates; Phosphorus Compounds; Prodrugs; Stavudine	2015
[CLINICAL AND PHARMACOECONOMIC RESULTS OF THE USAGE OF VARIOUS HIV REVERSE TRANSCRIPTASE INHIBITORS IN THE SCHEMES OF ANTIRETROVIRAL THERAPY OF PATIENT RECEIVING THERAPY FOR THE CHRONIC HEPATITIS C VIRUS]. Voprosy virusologii, 2016, Volume: 61, Issue:1 Topics: Adult; Alanine Transaminase; Biomarkers; Blood Platelets; CD4-Positive T-Lymphocytes; Cell Count; Coinfection; Dideoxynucleosides; Female; Genotype; Hemoglobins; Hepacivirus; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2016