organophosphonates has been researched along with rilpivirine in 26 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (rilpivirine) | Trials (rilpivirine) | Recent Studies (post-2010) (rilpivirine) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 580 | 93 | 513 |
| Protein | Taxonomy | organophosphonates (IC50) | rilpivirine (IC50) |
|---|---|---|---|
| Gag-Pol polyprotein | HIV-1 M:B_HXB2R | 0.068 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 6.1612 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 1.7406 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.3635 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.2818 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.3363 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.5 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.0759 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 25 (96.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Susman, E | 1 |
| Debyser, Z; Desimmie, BA; Schrijvers, R | 1 |
| Andrade-Villanueva, J; Boven, K; Clotet, B; Cohen, CJ; Crauwels, H; Fourie, J; Johnson, MA; Rimsky, LT; Ruxrungtham, K; Vanveggel, S; Wu, H; Zorrilla, C | 1 |
| Boven, K; Cahn, P; Crauwels, H; Grinsztejn, B; Lazzarin, A; Mills, A; Molina, JM; Rimsky, LT; Saag, M; Supparatpinyo, K; Vanveggel, S; Walmsley, S | 1 |
| Arasteh, K; Boven, K; Crauwels, H; De Wet, J; Gathe, J; Gold, J; Hodder, S; Kumar, P; Mohapi, L; Short, W; Vanveggel, S | 1 |
| De Clercq, E | 1 |
| Calvez, V; Flandre, P; Fofana, DB; Fourati, S; Katlama, C; Lambert, S; Malet, I; Marcelin, AG; Sayon, S; Simon, A; Soulie, C; Wirden, M | 1 |
| Lyseng-Williamson, KA; Scott, LJ | 1 |
| Calvez, V; Charpentier, C; Descamps, D; Flandre, P; Fofana, DB; Fourati, S; Lambert-Niclot, S; Marcelin, AG; Masquelier, B; Morand-Joubert, L; Soulié, C; Storto, A; Visseaux, B; Wirden, M | 1 |
| Aldir, I; Horta, A; Serrado, M | 1 |
| Cheng, A; Custodio, JM; Hepner, M; Kearney, BP; Ling, KH; Ramanathan, S; Yin, X | 1 |
| Estrada, V; Portilla, J | 1 |
| Feng, JY; Kulkarni, R; Miller, MD; White, KL | 1 |
| Calvez, V; Charpentier, C; Descamps, D; Flandre, P; Fofana, D; Fourati, S; Lambert-Niclot, S; Marcelin, AG; Masquelier, B; Morand-Joubert, L; Soulie, C; Storto, A; Wirden, M | 1 |
| McGowan, I | 1 |
| Behrens, G; Bosse, M; Chuck, SK; Cohen, C; DeMorin, J; Elion, RA; Mills, A; Nelson, M; Orkin, C; Rijnders, B; Rimsky, L; Stevens, M; Thorpe, D; Vanveggel, S; White, K; Zhong, L | 1 |
| Hsiao, CB; Ma, Q; Sawyer, JR | 1 |
| Rijnders, BJ; Rokx, C; Verbon, A | 1 |
| Allavena, C; André-Garnier, E; Billaud, E; Bonnet, B; Bouchez, S; Bouquié, R; Boutoille, D; Dailly, E; Pineau, S; Raffi, F; Raveleau, A; Reliquet, V | 1 |
| Amiel, C; Chas, J; Guessant, S; Hamidi, M; Kherallah, K; Lebrette, MG; Lependeven, C; Pialoux, G; Schneider, V | 1 |
| Baldeyrou, M; Batard, ML; Bernard-Henry, C; Cheneau, C; de Mautort, E; Fafi-Kremer, S; Gantner, P; Muret, P; Partisani, M; Priester, M; Reinhart, S; Rey, D | 1 |
| Camejo, RR; Cuffe, R; Gilchrist, KA; Lim, JW; Nichols, G; Patel, DA; Pulgar, S; Snedecor, SJ; Stephens, J; Sudharshan, L; Tang, WY | 1 |
| Bastard, JP; Dubourg, O; Harent, S; Lariven, S; Lescure, FX; Nguyen, LB; Peytavin, G; Visseaux, B; Yazdanpanah, Y | 1 |
| Boyd, A; Fonquernie, L; Girard, PM; Meynard, JL; Morand-Joubert, L; Surgers, L; Valin, N; Viala, C | 1 |
| Deeks, ED | 1 |
6 review(s) available for organophosphonates and rilpivirine
| Article | Year |
|---|---|
Where rilpivirine meets with tenofovir, the start of a new anti-HIV drug combination era.
Topics: Adenine; Animals; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Emtricitabine; Emtricitabine, Rilpivirine, Tenofovir Drug Combination; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Oxazines; Pyrimidines; Rilpivirine; Tenofovir | 2012 |
Single-tablet regimens in HIV: does it really make a difference?
Topics: Adenine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Emtricitabine; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Pyrimidines; Quinolones; Reverse Transcriptase Inhibitors; Rilpivirine; Tablets; Tenofovir; Thiazoles | 2014 |
[Mechanism of action and pharmacokinetics of rilpivirine].
Topics: Adenine; Adult; Aged; Animals; Anti-HIV Agents; Biological Availability; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Deoxycytidine; Drug Administration Routes; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Emtricitabine; Food-Drug Interactions; Half-Life; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Intestinal Absorption; Molecular Structure; Nanoparticles; Nitriles; Organophosphonates; Proton Pump Inhibitors; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir | 2013 |
An overview of antiretroviral pre-exposure prophylaxis of HIV infection.
Topics: Adenine; Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Male; Maraviroc; Medication Adherence; Nitriles; Organophosphonates; Pre-Exposure Prophylaxis; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Triazoles | 2014 |
48-week efficacy and safety of dolutegravir relative to commonly used third agents in treatment-naive HIV-1-infected patients: a systematic review and network meta-analysis.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Emtricitabine; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; Humans; Lamivudine; Lipids; Lopinavir; Nitriles; Organophosphonates; Oxazines; Piperazines; Pyridones; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Randomized Controlled Trials as Topic; Rilpivirine; Ritonavir; Tenofovir; Time Factors; Treatment Outcome; Viral Load | 2014 |
Emtricitabine/rilpivirine/tenofovir disoproxil fumarate single-tablet regimen: a review of its use in HIV infection.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Tablets; Tenofovir | 2014 |
5 trial(s) available for organophosphonates and rilpivirine
| Article | Year |
|---|---|
Rilpivirine versus efavirenz with two background nucleoside or nucleotide reverse transcriptase inhibitors in treatment-naive adults infected with HIV-1 (THRIVE): a phase 3, randomised, non-inferiority trial.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Double-Blind Method; Drug Administration Schedule; Emtricitabine; Female; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Nitriles; Nucleosides; Nucleotides; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Treatment Outcome; Viral Load | 2011 |
Rilpivirine versus efavirenz with tenofovir and emtricitabine in treatment-naive adults infected with HIV-1 (ECHO): a phase 3 randomised double-blind active-controlled trial.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Double-Blind Method; Drug Administration Schedule; Emtricitabine; Female; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Nitriles; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Treatment Outcome; Viral Load | 2011 |
Effect of gender and race on the week 48 findings in treatment-naïve, HIV-1-infected patients enrolled in the randomized, phase III trials ECHO and THRIVE.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black or African American; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Sex Factors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2012 |
Effect of food on rilpivirine/emtricitabine/tenofovir disoproxil fumarate, an antiretroviral single-tablet regimen for the treatment of HIV infection.
Topics: Adenine; Adult; Anti-HIV Agents; Cross-Over Studies; Deoxycytidine; Drug Combinations; Emtricitabine; Fasting; Female; Food-Drug Interactions; HIV Infections; Humans; Male; Middle Aged; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Tablets; Tenofovir; Young Adult | 2014 |
Rilpivirine versus efavirenz with emtricitabine/tenofovir disoproxil fumarate in treatment-naïve HIV-1-infected patients with HIV-1 RNA ≤100,000 copies/mL: week 96 pooled ECHO/THRIVE subanalysis.
Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiviral Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nitriles; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; RNA, Viral; Tenofovir; Time Factors; Treatment Outcome; Viral Load; Young Adult | 2014 |
15 other study(ies) available for organophosphonates and rilpivirine
| Article | Year |
|---|---|
HIV Pathogenesis and Treatment - Third International AIDS Society Conference.
Topics: Adenine; Antiretroviral Therapy, Highly Active; Chemistry, Pharmaceutical; Clinical Trials as Topic; Congresses as Topic; Darunavir; Drugs, Investigational; Enfuvirtide; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Peptide Fragments; Pyrimidines; Receptors, CCR5; Reverse Transcriptase Inhibitors; Rilpivirine; Societies, Scientific; Sulfonamides; Tenofovir; Zalcitabine | 2005 |
Rilpivirine: a step forward in tailored HIV treatment.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials, Phase III as Topic; Cyclopropanes; Delavirdine; Deoxycytidine; Drug Design; Drug Resistance, Viral; Emtricitabine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Multicenter Studies as Topic; Mutation; Nevirapine; Nitriles; Organophosphonates; Pyrimidines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Viral Load | 2011 |
FDA notifications. Complera approved.
Topics: Adenine; Deoxycytidine; Drug Approval; Drug Combinations; Drug Labeling; Emtricitabine; HIV Infections; Humans; Nitriles; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; United States; United States Food and Drug Administration | 2011 |
E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure.
Topics: Adenine; Anti-HIV Agents; APOBEC Deaminases; Cytidine Deaminase; Cytosine Deaminase; DNA Mutational Analysis; Drug Resistance, Viral; Female; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Lysine; Male; Methionine; Mutation; Nitriles; Organophosphonates; Pyridazines; Pyrimidines; Rilpivirine; Tenofovir; Treatment Failure; Virus Replication | 2012 |
Emtricitabine/rilpivirine/tenofovir disoproxil fumarate single-tablet regimen: a guide to its use in HIV-1 infection.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Patient Compliance; Pyrimidines; Rilpivirine; RNA, Viral; Tenofovir; Time Factors; Treatment Outcome | 2012 |
Prevalence of pre-existing resistance-associated mutations to rilpivirine, emtricitabine and tenofovir in antiretroviral-naive patients infected with B and non-B subtype HIV-1 viruses.
Topics: Adenine; Antiretroviral Therapy, Highly Active; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genotype; HIV Infections; HIV-1; Humans; Mutation; Nitriles; Organophosphonates; Prevalence; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir | 2013 |
Dead-end complexes contribute to the synergistic inhibition of HIV-1 RT by the combination of rilpivirine, emtricitabine, and tenofovir.
Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Drug Synergism; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Nitriles; Organophosphonates; Pyrimidines; Reverse Transcription; Rilpivirine; Tenofovir; Virus Cultivation | 2014 |
Rilpivirine, emtricitabine and tenofovir resistance in HIV-1-infected rilpivirine-naive patients failing antiretroviral therapy.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Sequence Analysis, DNA; Tenofovir; Treatment Failure | 2014 |
Single-tablet, once-daily treatment regimens for HIV.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cobicistat; Cyclopropanes; Cytochrome P-450 CYP3A Inhibitors; Deoxycytidine; Drug Combinations; Emtricitabine; HIV Infections; HIV Integrase Inhibitors; HIV Reverse Transcriptase; Humans; Nitriles; Organophosphonates; Pyrimidines; Quinolones; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Thiazoles | 2014 |
Successful switch to rilpivirine/tenofovir/emtricitabine in HIV-1-infected patients with an isolated K103N mutation acquired during prior nonnucleoside reverse transcriptase inhibitor therapy.
Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Drug Substitution; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Mutation; Nitriles; Organophosphonates; Pilot Projects; Prospective Studies; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Viral Load; Young Adult | 2014 |
Switching from tenofovir/emtricitabine and nevirapine to a tenofovir/emtricitabine/rilpivirine single-tablet regimen in virologically suppressed, HIV-1-infected subjects.
Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Drug Combinations; Drug Substitution; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Nitriles; Organophosphonates; Prospective Studies; Pyrimidines; Rilpivirine; Tenofovir; Treatment Outcome; Viral Load | 2014 |
Initiation of rilpivirine, tenofovir and emtricitabine (RPV/TDF/FTC) regimen in 363 patients with virological vigilance assessment in 'real life'.
Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genotype; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Tenofovir | 2014 |
Switching to emtricitabine, tenofovir and rilpivirine as single tablet regimen in virologically suppressed HIV-1-infected patients: a cohort study.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Cohort Studies; Deoxycytidine; Drug Combinations; Drug Substitution; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nitriles; Organophosphonates; Pyrimidines; Retrospective Studies; Rilpivirine; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load | 2015 |
Skeletal muscle toxicity associated with emtricitabine/rilpivirine/tenofovir fixed-dose combination: a case report.
Topics: Adenine; Deoxycytidine; Drug Combinations; Emtricitabine; Histocytochemistry; Humans; Lipodystrophy; Male; Microscopy; Middle Aged; Muscle, Skeletal; Muscular Atrophy, Spinal; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Tenofovir | 2014 |
Evaluation of the efficacy and safety of switching to tenofovir, emtricitabine, and rilpivirine in treatment-experienced patients.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Male; Middle Aged; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Tenofovir; Young Adult | 2015 |