organophosphonates has been researched along with phosphoramidon in 10 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (phosphoramidon) | Trials (phosphoramidon) | Recent Studies (post-2010) (phosphoramidon) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 781 | 12 | 33 |
| Protein | Taxonomy | organophosphonates (IC50) | phosphoramidon (IC50) |
|---|---|---|---|
| Thermolysin | Bacillus thermoproteolyticus | 0.033 | |
| Neprilysin | Rattus norvegicus (Norway rat) | 0.0578 | |
| Neprilysin | Oryctolagus cuniculus (rabbit) | 0.0028 | |
| Neprilysin | Homo sapiens (human) | 0.0405 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.615 | |
| Endothelin-converting enzyme 1 | Homo sapiens (human) | 1.0695 | |
| P2Y purinoceptor 12 | Homo sapiens (human) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Held, HD; Raschak, M; Uhlig, S | 1 |
| Hoang, MV; Sansom, CE; Turner, AJ | 1 |
| Barker, S; Mitchell, JA; Rees, GM; Walcot, NR; Warner, TD; Wood, EG; Woods, M | 1 |
| Adler, M; Cornille, F; Hackley, BE; Kane, CT; Nicholson, JD; Starks, DF | 1 |
| Battistini, B; McKay, KO; Yap, EY | 1 |
| Battistini, B; Jeng, AY; Wright, JL | 1 |
| Emoto, N | 1 |
| D'Orléans-Juste, P; Fecteau, MH; Honoré, JC; Labonté, J; Plante, M; Rae, GA | 1 |
| Donahue, MG; Johnston, JN | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Ozawa, Y; Taguchi, K | 1 |
1 review(s) available for organophosphonates and phosphoramidon
| Article | Year |
|---|---|
[Physiological and pathophysiological roles of the endothelin converting enzymes].
Topics: Animals; Aspartic Acid Endopeptidases; Benzazepines; Benzofurans; Drug Design; Endothelin-Converting Enzymes; Glycopeptides; Heart Failure; Humans; Hypertension; Metalloendopeptidases; Mice; Mice, Knockout; Myocardial Infarction; Organophosphonates; Phenylalanine; Tetracyclines; Tetrazoles | 2004 |
9 other study(ies) available for organophosphonates and phosphoramidon
| Article | Year |
|---|---|
Rat big endothelin-1-induced bronchoconstriction and vasoconstriction in the isolated perfused rat lung: role of endothelin converting enzyme and neutral endopeptidase 24.11.
Topics: Airway Resistance; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Bronchoconstriction; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Female; Glycopeptides; Lung; Metalloendopeptidases; Neprilysin; Organophosphonates; Perfusion; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Tetrazoles; Thiorphan; Vascular Resistance; Vasoconstriction | 1997 |
Molecular modelling and site-directed mutagenesis of the active site of endothelin-converting enzyme.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Binding Sites; CHO Cells; Conserved Sequence; Cricetinae; Endothelin-Converting Enzymes; Gene Expression; Glycopeptides; Humans; Metalloendopeptidases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neprilysin; Organophosphonates; Protease Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Tetrazoles; Thermolysin | 1998 |
Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme.
Topics: Aspartic Acid Endopeptidases; Cells, Cultured; Cytokines; Drug Interactions; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Humans; Interferon-gamma; Mammary Arteries; Metalloendopeptidases; Muscle, Smooth, Vascular; Organophosphonates; Phenylalanine; Protease Inhibitors; RNA, Messenger; Saphenous Vein; Tetrazoles; Tumor Necrosis Factor-alpha | 1999 |
Evaluation of phosphoramidon and three synthetic phosphonates for inhibition of botulinum neurotoxin B catalytic activity.
Topics: Botulinum Toxins; Botulinum Toxins, Type A; Catalysis; Glycopeptides; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Structure-Activity Relationship; Zinc Sulfate | 1999 |
Contraction to big endothelin-1, big endothelin-2 and big endothelin-3, and endothelin-converting enzyme inhibition in human isolated bronchi.
Topics: Aspartic Acid Endopeptidases; Bronchi; Endothelin-1; Endothelin-2; Endothelin-3; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Glycopeptides; Humans; In Vitro Techniques; Lung; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Tetrazoles | 2000 |
Effect of ECE and NEP inhibition on cigarette smoke-induced cell proliferation in the rat lung.
Topics: Administration, Inhalation; Animals; Bromodeoxyuridine; Bronchi; Cell Division; Drug Interactions; Endothelium, Vascular; Glycopeptides; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Smoking; Tetrazoles | 2001 |
Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo.
Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Blood Pressure; Endothelin-1; Endothelin-Converting Enzymes; Female; Glycopeptides; Heart Ventricles; Injections; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Peptide Fragments; Protease Inhibitors; Rabbits; Receptors, Endothelin; Thiorphan | 2005 |
Preparation of a protected phosphoramidon precursor via an H-phosphonate coupling strategy.
Topics: Glycopeptides; Organophosphonates | 2006 |
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.
Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Blood Glucose; Body Weight; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Heart; Lipids; Lysine; Male; Metalloendopeptidases; Myocardium; Oligopeptides; Organ Size; Organophosphonates; Peptides, Cyclic; Perfusion; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Thiorphan; Vasoconstriction | 2010 |