Page last updated: 2024-09-05

organophosphonates and paraoxon

organophosphonates has been researched along with paraoxon in 7 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(paraoxon)
Trials
(paraoxon)
Recent Studies (post-2010) (paraoxon)
9,9688803,5961,5163354

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)paraoxon (IC50)
Fatty-acid amide hydrolase 1Mus musculus (house mouse)5.9
Carbonic anhydrase 1Homo sapiens (human)0.338
Carbonic anhydrase 2Homo sapiens (human)0.059
CholinesteraseHomo sapiens (human)0.007
AcetylcholinesteraseMus musculus (house mouse)0.013
AcetylcholinesteraseHomo sapiens (human)0.01
Carbonic anhydrase 13Mus musculus (house mouse)1.021

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ntiforo, C; Stein, M1
Hong, SB; Raushel, FM1
Johnson, J; Kovach, IM; Massiah, MA; Mildvan, AS; Reddy, PM; Rosenberry, TL; Viragh, C1
Ghanem, E; Li, Y; Raushel, FM; Xu, C1
Erickson, B; Ko, KW; Lehner, R1
Colby, T; Kaiser, M; Kaschani, F; Nickel, S; van der Hoorn, RA1
Borai, A; Hala, SM; Jaber, BM; Petroianu, GA; Rizvi, SA; Saleh, AM; Saleh, NA1

Other Studies

7 other study(ies) available for organophosphonates and paraoxon

ArticleYear
Organophosphorus compounds and carbamates as perilysosomal modifiers.
    Chemico-biological interactions, 1974, Volume: 9, Issue:1

    Topics: Acid Phosphatase; Animals; Carbamates; Cathepsins; Chromatography, Thin Layer; Hydrocortisone; Hydrogen-Ion Concentration; Liver; Lysosomes; Malathion; Male; Organophosphonates; Organophosphorus Compounds; Paraoxon; Rats; Sucrose; Sulfatases; Time Factors; Ultracentrifugation

1974
Inhibitors directed towards the binuclear metal center of phosphotriesterase.
    Journal of enzyme inhibition, 1997, Volume: 12, Issue:3

    Topics: Aryldialkylphosphatase; Cadmium; Cations, Divalent; Enzyme Inhibitors; Esterases; Organophosphonates; Paraoxon; Phosphates; Pseudomonas; Substrate Specificity; Zinc

1997
Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies.
    Biochemistry, 2001, May-15, Volume: 40, Issue:19

    Topics: Acetophenones; Acetylcholinesterase; Animals; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors; Dimerization; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Nitrophenols; Nuclear Magnetic Resonance, Biomolecular; Organophosphonates; Paraoxon; Protons; Recombinant Proteins; Torpedo

2001
Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX.
    Biochemistry, 2007, Aug-07, Volume: 46, Issue:31

    Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Disulfoton; Enterobacter aerogenes; Kinetics; Microbial Viability; Molecular Structure; Mutation; Nitrophenols; Organophosphates; Organophosphonates; Organothiophosphorus Compounds; Paraoxon; Phenols; Phosphoric Diester Hydrolases; Phosphoric Triester Hydrolases; Recombinant Proteins; Substrate Specificity

2007
Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes.
    Biochimica et biophysica acta, 2009, Volume: 1791, Issue:12

    Topics: Animals; Apolipoproteins B; Carboxylic Ester Hydrolases; Cell Line, Tumor; Fatty Acids; Glycerol; Hepatocytes; Lipid Metabolism; Mice; Oleic Acid; Organophosphonates; Oxidation-Reduction; Paraoxon; Rats; Recombinant Proteins; Subcellular Fractions; Transfection; Triglycerides

2009
A para-nitrophenol phosphonate probe labels distinct serine hydrolases of Arabidopsis.
    Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2

    Topics: Arabidopsis; Carboxylesterase; Nitrophenols; Organophosphonates; Paraoxon; Plant Proteins; Proteomics

2012
Protective effect of metoclopramide against organophosphate-induced apoptosis in the murine skin fibroblast L929.
    Journal of applied toxicology : JAT, 2018, Volume: 38, Issue:3

    Topics: Animals; Antidotes; Apoptosis; Caspase 3; Cell Line; Cytoprotection; Dose-Response Relationship, Drug; Fibroblasts; Malathion; Membrane Potential, Mitochondrial; Metoclopramide; Mice; Organophosphonates; Paraoxon; Poly(ADP-ribose) Polymerases; Skin

2018