Page last updated: 2024-09-05

organophosphonates and paclitaxel

organophosphonates has been researched along with paclitaxel in 9 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(paclitaxel)
Trials
(paclitaxel)
Recent Studies (post-2010) (paclitaxel)
9,9688803,59631,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diasio, RB; Stagg, MP1
Kennedy, MJ1
Torres, G1
Chamani, J; Hakimelahi, GH; Hakimelahi, S; Hassanzadeh, F; Jain, ML; Khodarahmi, GA; Kulatheeswaran, R; Luo, FT; Ly, TW; Moosavi-Movahedi, AA; Pasdar, M; Shia, KS; Xue, C; Yen, CF1
Kennedy, S; Wadsworth, RM; Wainwright, CL1
Bian, JS; Boelsterli, UA; Chan, E; Chan, SY; Duan, W; Ho, PC; Huang, M; Li, X; Tan, TM; Tian, Q; Xiong, W; Yang, H; Zhang, J; Zhou, S; Zhu, YZ1
Bieberich, E; Bryant, L; Chen, C; Chen, Z; Cuzzocrea, S; Doyle, T; Esposito, E; Janes, K; Kamocki, K; Li, C; Little, JW; Neumann, WL; Nicol, G; Obeid, L; Petrache, I; Salvemini, D; Snider, A1
McKinlay, CJ; Waymouth, RM; Wender, PA1
Aktaş, Y; Bilensoy, E; Sandler, N; Varan, C; Wickström, H1

Reviews

2 review(s) available for organophosphonates and paclitaxel

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990
Metastatic breast cancer.
    Current opinion in oncology, 1996, Volume: 8, Issue:6

    Topics: Adenine; Antibodies, Monoclonal; Antibodies, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Deoxycytidine; Diphosphonates; Docetaxel; Doxorubicin; Enzyme Inhibitors; Female; Gemcitabine; Humans; Imides; Intercalating Agents; Isoquinolines; Naphthalimides; Neoplasm Metastasis; Neoplasm Proteins; Organophosphonates; Paclitaxel; Randomized Controlled Trials as Topic; Salvage Therapy; Taxoids; Topoisomerase II Inhibitors; Treatment Outcome

1996

Trials

1 trial(s) available for organophosphonates and paclitaxel

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990

Other Studies

7 other study(ies) available for organophosphonates and paclitaxel

ArticleYear
Second National Retrovirus conference: a further report.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:3

    Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cause of Death; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Paclitaxel; Reverse Transcriptase Inhibitors; Sarcoma, Kaposi; Tuberculosis

1995
Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity.
    Bioorganic & medicinal chemistry, 2003, Oct-01, Volume: 11, Issue:20

    Topics: 4-Butyrolactone; Adenine; Animals; Antineoplastic Agents; Cell Division; Cell Line, Tumor; Cell Nucleus; Diphosphates; Drug Design; Drug Screening Assays, Antitumor; Furans; Humans; Microtubules; Organophosphonates; Paclitaxel; Prodrugs; Ribonucleoside Diphosphate Reductase; Solubility; Structure-Activity Relationship

2003
Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.
    European journal of pharmacology, 2003, Nov-14, Volume: 481, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkyl and Aryl Transferases; Angioplasty, Balloon; Animals; Antineoplastic Agents; Azulenes; Calcimycin; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Farnesyltranstransferase; Fucose; In Vitro Techniques; Monoterpenes; Organophosphonates; Paclitaxel; Serotonin; Swine; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2003
Human multidrug resistance associated protein 4 confers resistance to camptothecins.
    Pharmaceutical research, 2005, Volume: 22, Issue:11

    Topics: Adenine; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line; Drug Resistance, Neoplasm; Glutathione; Humans; Irinotecan; Methotrexate; Multidrug Resistance-Associated Proteins; Organophosphonates; Paclitaxel

2005
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.
    The Journal of biological chemistry, 2014, Jul-25, Volume: 289, Issue:30

    Topics: Anilides; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Enzyme Activation; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Indans; Lysophospholipids; Male; Neuralgia; Organophosphonates; Oxadiazoles; Paclitaxel; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Thiazoles; Thiophenes

2014
Cell-Penetrating, Guanidinium-Rich Oligophosphoesters: Effective and Versatile Molecular Transporters for Drug and Probe Delivery.
    Journal of the American Chemical Society, 2016, Mar-16, Volume: 138, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Fluorescent Dyes; Guanidine; HeLa Cells; Humans; Jurkat Cells; Mice; Microscopy, Confocal; Organophosphonates; Paclitaxel

2016
Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administration.
    International journal of pharmaceutics, 2017, Oct-15, Volume: 531, Issue:2

    Topics: Adenocarcinoma; Administration, Intravaginal; Antiviral Agents; Cell Line, Tumor; Cervix Uteri; Cidofovir; Cyclodextrins; Cytosine; Drug Delivery Systems; Female; Humans; Nanoparticles; Organophosphonates; Paclitaxel; Printing; Solubility; Uterine Cervical Neoplasms

2017