organophosphonates has been researched along with kainic acid in 3 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (kainic acid) | Trials (kainic acid) | Recent Studies (post-2010) (kainic acid) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 9,540 | 3 | 1,775 |
| Protein | Taxonomy | organophosphonates (IC50) | kainic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 4 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.0126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cordi, AA; Desos, P; Lepagnol, JM; Lestage, P; Morain, P | 1 |
| Dai, WM; Ebert, B; Lambert, JD; Madsen, U | 1 |
| Ahring, PK; Egebjerg, J; Gajhede, M; Hald, H; Kastrup, JS; Liljefors, T; Madsen, U; Naur, P; Pickering, DS; Schousboe, A; Sprogøe, D; Timmermann, DB | 1 |
3 other study(ies) available for organophosphonates and kainic acid
| Article | Year |
|---|---|
Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Kainic Acid; Mice; Molecular Structure; N-Methylaspartate; Neuroprotective Agents; Organophosphonates; Quinolones; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Xenopus | 1996 |
Studies of the antagonist actions of (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl] propionic acid (ATPO) on non-NMDA receptors in cultured rat neurones.
Topics: Adrenal Cortex Hormones; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Isoxazoles; Kainic Acid; Neurons; Organophosphonates; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1998 |
Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Humans; Isoxazoles; Kainic Acid; Ligands; Organophosphonates; Protein Binding; Protein Structure, Tertiary; Receptors, AMPA; Receptors, Kainic Acid | 2007 |