Page last updated: 2024-09-05

organophosphonates and indinavir sulfate

organophosphonates has been researched along with indinavir sulfate in 23 studies

Compound Research Comparison

Studies (organophosphonates)	Trials (organophosphonates)	Recent Studies (post-2010) (organophosphonates)	Studies (indinavir sulfate)	Trials (indinavir sulfate)	Recent Studies (post-2010) (indinavir sulfate)
9,968	880	3,596	1,834	328	146

Protein Interaction Comparison

Protein	Taxonomy	indinavir sulfate (IC50)
Gag-Pol polyprotein	Human immunodeficiency virus type 1 (BRU ISOLATE)	0.0004
Gag polyprotein	HIV-1 M:B_MN	0.02
Cytochrome P450 3A4	Homo sapiens (human)	0.2
Gag-Pol polyprotein	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	0.0261
Substance-K receptor	Homo sapiens (human)	5.101
Thromboxane-A synthase	Homo sapiens (human)	1.851
Protease	Human immunodeficiency virus 1	0.0349
Multidrug and toxin extrusion protein 2	Homo sapiens (human)	7.8
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	3.8
Protease	Human immunodeficiency virus 1	0.0044

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (13.04)	18.2507
2000's	14 (60.87)	29.6817
2010's	6 (26.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Galegov, GA; Kraevskiĭ, AA; Selimova, LM	1
Chalifoux, L; Chen, ZW; Enimi, EA; Gastron, M; Henckler, B; Letvin, NL; Miller, M; Sehgal, N; Sehgal, P; Shen, L; Shen, Y; Simon, M; Zhou, D	1
Di Perri, G; Maiello, A; Quario, M; Racca, D; Sinicco, A; Zeme, DA	1
Aberg, JA; Bennett, KK; Bessen, LJ; Brosgart, C; DeGruttola, V; Eron, JJ; Gulick, RM; Hammer, SM; Holohan, MK; Karol, CN; Lewis, RH; Mellors, JW; Mitsuyasu, RT; Rogers, MD; Saah, AJ; Sheiner, L; Vaida, F; Valentine, FT; Wheat, LJ	1
Bakshi, KK; Chen, J; Condra, JH; Danovich, RM; DiNubile, MJ; Graham, DJ; Haas, DW; Holder, DJ; Rhodes, RR; Saah, AJ; Shivaprakash, M	1
Bassett, R; Currier, JS; DeGruttola, V; Demeter, LM; Eron, JJ; Fischl, MA; Hammer, SM; Mellors, JW; Morse, GD; Santana, JL; Squires, KE	1
Chen, ZW; Du, GZ; Huang, D; Letvin, NL; Miller, MD; Qiu, L; Sehgal, P; Shen, L; Shen, Y	1
Cauda, R; Cingolani, A; De Luca, A; Di Giambenedetto, S; Marzocchetti, A; Pompucci, A; Scoppettuolo, G; Tumbarello, M; Vago, G	1
Anastos, K; Cohen, M; Cole, S; Hessol, NA; Justman, J; Kaplan, RC; Lu, D; Shi, Q; Tien, PC; Vigen, C; Young, M	1
Beniowski, M; Gargalianos, P; Gatell, J; Kirk, O; Lundgren, JD; Mocroft, A; Reiss, P; Staszewski, S; Viard, JP; Zilmer, K	1
Bui, T; Choi, SU; Ho, RJ	1
Doerries, R; Drechsler, H; Gass, A; Hardmeier, M; Kuhle, J; Mehling, M; Ruegg, S	1
Chow, WA; Guan, M; Jiang, C	1
Campbell, LJ; Fisher, M; Hendry, BM; Holt, SG; Ibrahim, F; Post, FA	1
Moreno, V; Valencia, ME	1
Bonnet, F; Dabis, F; Déti, EK; Dupon, M; Lawson-Ayayi, S; Malvy, D; Morlat, P; Neau, D; Pellegrin, JL; Tchamgoué, S; Thiébaut, R	1
Jao, J; Wyatt, CM	1
Beniowski, M; De Wit, S; Gatell, J; Kirk, O; Ledergerber, B; Lundgren, JD; Mocroft, A; Phillips, AN; Reiss, P; Sedlacek, D	1
Bansi, L; Campbell, LJ; Cheserem, E; Hendry, BM; Ibrahim, F; Naftalin, C; Post, FA; Roe, J; Sabin, C	1
Cooper, RD; Tonelli, M	1
Freeling, JP; Ho, RJ; Koehn, J; Shu, C; Sun, J	1

Reviews

3 review(s) available for organophosphonates and indinavir sulfate

Article	Year
Anti-HIV drugs for cancer therapeutics: back to the future? The Lancet. Oncology, 2009, Volume: 10, Issue:1 Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cidofovir; Cytosine; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; Neoplasms; Organophosphonates; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine	2009
Antiretroviral medications: adverse effects on the kidney. Advances in chronic kidney disease, 2010, Volume: 17, Issue:1 Topics: Adenine; AIDS-Associated Nephropathy; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Humans; Indinavir; Kidney; Organophosphonates; Tenofovir	2010
Renal disease associated with antiretroviral therapy in the treatment of HIV. Nephron. Clinical practice, 2011, Volume: 118, Issue:3 Topics: Adenine; Anti-Retroviral Agents; Atazanavir Sulfate; HIV Infections; Humans; Indinavir; Kidney Diseases; Oligopeptides; Organophosphonates; Pyridines; Tenofovir	2011

Trials

3 trial(s) available for organophosphonates and indinavir sulfate

Article	Year
Dual vs single protease inhibitor therapy following antiretroviral treatment failure: a randomized trial. JAMA, 2002, Jul-10, Volume: 288, Issue:2 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Disease Progression; Double-Blind Method; Drug Resistance, Viral; Female; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Male; Nelfinavir; Organophosphonates; Oxazines; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Saquinavir; Sulfonamides; Treatment Failure; Viral Load	2002
Treatment with indinavir, efavirenz, and adefovir after failure of nelfinavir therapy. The Journal of infectious diseases, 2003, Apr-01, Volume: 187, Issue:7 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Male; Middle Aged; Nelfinavir; Organophosphonates; Oxazines; Treatment Failure	2003
A randomized trial of nelfinavir and abacavir in combination with efavirenz and adefovir dipivoxil in HIV-1-infected persons with virological failure receiving indinavir. Antiviral therapy, 2003, Volume: 8, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; HIV-1; Humans; Indinavir; Male; Nelfinavir; Organophosphonates; Oxazines; Phenotype; Reverse Transcriptase Inhibitors; Treatment Failure	2003

Other Studies

17 other study(ies) available for organophosphonates and indinavir sulfate

Article	Year
[Combination of phosphazide and crixivan inhibit replication of HIV-1 strains that are resistant to azidothymidine]. Doklady Akademii nauk, 1999, Volume: 369, Issue:6 Topics: Anti-HIV Agents; Azides; Cell Line; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Microbial Sensitivity Tests; Organophosphonates; Reverse Transcriptase Inhibitors; Thymidine; Virus Replication; Zidovudine	1999
Update on antivirals. Project Inform perspective, 1997, Issue:22 Topics: Adenine; Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Clinical Trials as Topic; Dosage Forms; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Saquinavir; Tenofovir; Viral Load	1997
CRIA clinical trials. Newsline (People with AIDS Coalition of New York), 1998 Topics: Adenine; Alkynes; Anabolic Agents; Anti-HIV Agents; Benzoxazines; Blood Glucose; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Male; Organophosphonates; Oxandrolone; Oxazines; Patient Selection; Reverse Transcriptase Inhibitors; Weight Loss	1998
Antiretroviral agents restore Mycobacterium-specific T-cell immune responses and facilitate controlling a fatal tuberculosis-like disease in Macaques coinfected with simian immunodeficiency virus and Mycobacterium bovis BCG. Journal of virology, 2001, Volume: 75, Issue:18 Topics: Adenine; Animals; Antiviral Agents; Cells, Cultured; HIV Protease Inhibitors; Indinavir; Macaca mulatta; Macaca nemestrina; Mycobacterium bovis; Nelfinavir; Organophosphonates; Organophosphorus Compounds; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocytes; Tenofovir; Tuberculosis	2001
A case of flare syndrome. Le infezioni in medicina, 2001, Volume: 9, Issue:3 Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine	2001
Development of Vgamma2Vdelta2+ T cell responses during active mycobacterial coinfection of simian immunodeficiency virus-infected macaques requires control of viral infection and immune competence of CD4+ T cells. The Journal of infectious diseases, 2004, Oct-15, Volume: 190, Issue:8 Topics: Adenine; Amino Acid Sequence; Animals; Cattle; CD4-Positive T-Lymphocytes; Disease Models, Animal; Drug Therapy, Combination; HIV Protease Inhibitors; Indinavir; Lung; Lymphocyte Count; Macaca mulatta; Macaca nemestrina; Molecular Sequence Data; Mycobacterium bovis; Organophosphonates; Receptors, Antigen, T-Cell, gamma-delta; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Tuberculosis, Bovine	2004
Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity? Neurology, 2004, Dec-28, Volume: 63, Issue:12 Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; CD4 Lymphocyte Count; Cidofovir; Cytosine; Dideoxynucleosides; Encephalitis; False Negative Reactions; Fatal Outcome; Humans; Immunocompromised Host; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Substance Abuse, Intravenous; Time Factors; Virus Activation; Zidovudine	2004
Association of serum lipid levels with HIV serostatus, specific antiretroviral agents, and treatment regimens. Journal of acquired immune deficiency syndromes (1999), 2007, May-01, Volume: 45, Issue:1 Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black People; Cholesterol; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Fasting; Female; Hispanic or Latino; HIV Infections; HIV Protease Inhibitors; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Multivariate Analysis; Nelfinavir; Nevirapine; Organophosphonates; Ritonavir; Stavudine; Tenofovir; Triglycerides; United States; White People	2007
Chronic renal failure among HIV-1-infected patients. AIDS (London, England), 2007, May-31, Volume: 21, Issue:9 Topics: Adenine; Adult; Aged; Anti-Retroviral Agents; CD4 Lymphocyte Count; Creatinine; Female; Glomerular Filtration Rate; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hypertension; Indinavir; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Organophosphonates; Prospective Studies; Reverse Transcriptase Inhibitors; Tenofovir	2007
pH-dependent interactions of indinavir and lipids in nanoparticles and their ability to entrap a solute. Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:2 Topics: Adenine; Drug Delivery Systems; Fluoresceins; Hydrogen-Ion Concentration; Indinavir; Lipids; Membrane Fluidity; Nanoparticles; Organophosphonates; Solubility; Tenofovir	2008
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement. Journal of neurovirology, 2008, Volume: 14, Issue:1 Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine	2008
Spectrum of chronic kidney disease in HIV-infected patients. HIV medicine, 2009, Volume: 10, Issue:6 Topics: Adenine; Adult; Age Factors; AIDS-Associated Nephropathy; Analysis of Variance; Anti-HIV Agents; Female; Glomerular Filtration Rate; HIV-1; Humans; Indinavir; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Prevalence; Tenofovir; United Kingdom	2009
[Atazanavir-induced nephrolithiasis]. Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:2 Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D, Chronic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lopinavir; Male; Nephrolithiasis; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir	2009
Prevalence and factors associated with renal impairment in HIV-infected patients, ANRS C03 Aquitaine Cohort, France. HIV medicine, 2010, Volume: 11, Issue:5 Topics: Adenine; Adult; Anti-HIV Agents; Body Mass Index; CD4 Lymphocyte Count; Creatinine; Epidemiologic Methods; Female; France; HIV Infections; Humans; Hypertension; Indinavir; Kidney; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Renal Insufficiency; Tenofovir	2010
Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients. AIDS (London, England), 2010, Jul-17, Volume: 24, Issue:11 Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Disease Progression; Epidemiologic Methods; Female; Glomerular Filtration Rate; HIV Seropositivity; HIV-1; Humans; Indinavir; Kidney Failure, Chronic; Male; Middle Aged; Oligopeptides; Organophosphonates; Pyridines; Reverse Transcriptase Inhibitors; Tenofovir	2010
Immunodeficiency and renal impairment are risk factors for HIV-associated acute renal failure. AIDS (London, England), 2010, Sep-10, Volume: 24, Issue:14 Topics: Acute Kidney Injury; Adenine; Adult; Atazanavir Sulfate; CD4 Lymphocyte Count; Cohort Studies; Female; Glomerular Filtration Rate; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; London; Male; Oligopeptides; Organophosphonates; Pyridines; Risk Factors; Tenofovir	2010
Anti-HIV drug-combination nanoparticles enhance plasma drug exposure duration as well as triple-drug combination levels in cells within lymph nodes and blood in primates. AIDS research and human retroviruses, 2015, Volume: 31, Issue:1 Topics: Adenine; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Carriers; Drug Combinations; HIV Infections; HIV Protease Inhibitors; HIV-1; Indinavir; Lipids; Lopinavir; Lymph Nodes; Macaca; Nanoparticles; Organophosphonates; Ritonavir; Tenofovir; Viral Load; Virus Latency	2015