organophosphonates has been researched along with imipenem, anhydrous in 2 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (imipenem, anhydrous) | Trials (imipenem, anhydrous) | Recent Studies (post-2010) (imipenem, anhydrous) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 4,784 | 391 | 1,397 |
| Protein | Taxonomy | organophosphonates (IC50) | imipenem, anhydrous (IC50) |
|---|---|---|---|
| Beta-lactamase | Pseudomonas aeruginosa | 0.15 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colwell, L; Dininno, FP; Hammond, ML; Hermes, JD; Ogawa, AM; Park, YW; Raghoobar, SL; Tan, Q; Wisniewski, D; Young, K | 1 |
| Adams, JL; Akhtar, A; Chen, Y; Jaishankar, P; Pemberton, OA; Renslo, AR; Shaw, LN | 1 |
2 other study(ies) available for organophosphonates and imipenem, anhydrous
| Article | Year |
|---|---|
Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Drug Resistance, Bacterial; Enzyme Inhibitors; Imipenem; Microbial Sensitivity Tests; Organophosphonates; Oximes; Pseudomonas aeruginosa; Thiophenes | 2011 |
Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Crystallography, X-Ray; Drug Design; Enterobacter cloacae; Escherichia coli; HEK293 Cells; Humans; Imipenem; Klebsiella pneumoniae; Ligands; Microsomes, Liver; Molecular Conformation; Organophosphonates; Pseudomonas aeruginosa | 2019 |