Page last updated: 2024-09-05

organophosphonates and guanosine monophosphate

organophosphonates has been researched along with guanosine monophosphate in 3 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(guanosine monophosphate)
Trials
(guanosine monophosphate)
Recent Studies (post-2010) (guanosine monophosphate)
9,9688803,5961,52620325

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arni, RK; Kreitman, RJ; Kumar, K; Walz, FG; Ward, RJ; Watanabe, L1
Cardozo, M; Chen, X; Deignan, J; Fu, Z; Guimaraes, C; Heath, J; Jeffries, S; Johnstone, S; Kayser, F; Kopecky, DJ; Lai, S; Li, S; Mihalic, J; Min, X; Shen, S; Shen, W; Thibault, S; Walker, N; Wang, Z; Xu, H1
Eng, WS; Guddat, LW; Hocková, D; Janeba, Z; Keough, DT; Naesens, LM; Špaček, P; West, NP; Woods, K1

Other Studies

3 other study(ies) available for organophosphonates and guanosine monophosphate

ArticleYear
Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
    Biochemistry, 1999, Feb-23, Volume: 38, Issue:8

    Topics: Aspergillus oryzae; Binding Sites; Catalysis; Crystallography, X-Ray; Deoxyuridine; Dinucleoside Phosphates; Guanosine Monophosphate; Ligands; Macromolecular Substances; Models, Molecular; Organophosphonates; Ribonuclease T1; Stereoisomerism; Substrate Specificity; Thermodynamics

1999
Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction.
    Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

    Topics: Animals; Crystallography, X-Ray; Drug Design; Eukaryotic Initiation Factor-4E; Guanine; Guanosine Monophosphate; Humans; Inhibitory Concentration 50; Models, Molecular; Organophosphonates; Phosphorous Acids; Protein Biosynthesis; Rabbits; Reticulocytes; RNA Caps; Structure-Activity Relationship

2012
First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.
    Journal of medicinal chemistry, 2015, Jun-11, Volume: 58, Issue:11

    Topics: Amino Acid Sequence; Antineoplastic Agents; Antitubercular Agents; Catalytic Domain; Cell Proliferation; Crystallography, X-Ray; Diphosphates; Enzyme Inhibitors; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Lung Neoplasms; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mycobacterium tuberculosis; Organophosphonates; Prodrugs; Protein Conformation; Sequence Homology, Amino Acid; Structure-Activity Relationship; Tuberculosis; Tumor Cells, Cultured

2015