Page last updated: 2024-09-05

organophosphonates and guanine

organophosphonates has been researched along with guanine in 528 studies

Compound Research Comparison

Studies (organophosphonates)	Trials (organophosphonates)	Recent Studies (post-2010) (organophosphonates)	Studies (guanine)	Trials (guanine)	Recent Studies (post-2010) (guanine)
9,968	880	3,596	16,278	822	4,809

Protein Interaction Comparison

Protein	Taxonomy	organophosphonates (IC50)	guanine (IC50)
Purine nucleoside phosphorylase	Homo sapiens (human)		5

Research

Studies (528)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (0.38)	18.7374
1990's	31 (5.87)	18.2507
2000's	119 (22.54)	29.6817
2010's	358 (67.80)	24.3611
2020's	18 (3.41)	2.80

Authors

Authors	Studies
Andrei, G; De Clercq, E; Desmyter, J; Goubau, P; Snoeck, R	1
Awan, AR; de la Fuente, R; Field, HJ	1
Cerný, J; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Sedivá, K; Veselý, J; Vlach, J; Votruba, I	1
Araullo-Cruz, T; De Clercq, E; Erzurum, S; Gordon, YJ; Romanowski, E; Seaberg, L; Tolman, R	1
De Clercq, E	2
Kim, CU; Luh, BY; Martin, JC	1
Baba, M; De Clercq, E; Mori, S; Shigeta, S	1
Fakunding, JL; Hershey, JW	1
Barnett, BB; Holy, A; Reist, EJ; Sidwell, RW; Smee, DF	1
Mimura, Y; Naito, T; Nitta, K; Shiota, H	1
Kelley, JL; Linn, JA; McLean, EW; Tuttle, JV	1
Holý, A; Merta, A; Stĕtina, R; Votruba, I	1
Beauchamp, LM; Rodriguez, ME; Sznaidman, ML; Tuttle, JV	1
Ahmed, PS; Brennan, TM; Bridges, CG; Casara, P; Hornsperger, JM; Navé, JF; Taylor, DL; Tyms, AS	1
Flaherty, JF	1
Reusser, P	1
Balzarini, J; Casara, P; De Clercq, E; Egberink, H; Hartmann, K; Navé, JF; Pannecouque, C; Vahlenkamp, T; Witvrouw, M	1
Cassady, KA; Whitley, RJ	1
Connelly, MC; Fridland, A; Lee, SH; Pisarev, VM	1
Katlama, C	1
Balzarini, J; De Clercq, E; Hatse, S; Naesens, L	2
Bílá, V; Holý, A; Lesková, V; Mejsnarová, B; Otová, B; Sladká, M; Votruba, I	1
Kaufman, HE; Thompson, HW; Varnell, ED	1
Chatterjee, S; Lakeman, FD; Nii, S; Tsukazaki, T; Whitley, RJ; Yamada, M; Yoshida, M	1
Bedard, J; Bowlin, T; Chan, L; Drach, J; Huffman, J; Lis, M; May, S; Rando, R; Sidwell, R; Tryphonas, L	1
Cheng, YC; Fu, L; Liu, SH	1
Carrilho, FJ; Kato, N; Lan, KH; Omata, M; Ono-Nita, SK; Shiratori, Y; Yoshida, H	1
Balzarini, J; De Clercq, E; Hatse, S; Naesens, L; Segers, C; Verbeken, E; Waer, M	1
Downey, KM; Kramata, P	1
Keating, MR	1
Civitico, G; Colledge, D; Locarnini, S; Shaw, T	1
De Clercq, E; Neyts, J; Ying, C	1
De Clercq, E; Furman, P; Neyts, J; Nicholson, W; Ying, C	1
Hoffman, VF; Skiest, DJ	1
Arnold, E; Das, K; Gibbs, CS; Sarafianos, SG; Westland, CE; Xiong, X; Yang, H	1
de Man, RA; Niesters, HG; Wolters, LM	1
De Clercq, E; Naesens, L	1
Boyer, N; Castelneau, C; Marcellin, P	1
Lok, AS	2
Abu Sheikha, G; La Colla, P; Loi, AG	1
Burroughs, AK; Papatheodoridis, GV; Sevastianos, V	1
Iino, S	2
Buster, EH; Schalm, SW; van der Eijk, AA	1
Hadziyannis, SJ; Papatheodoridis, GV	1
Ala, A; Dieterich, DT	1
Clarke, HE; Maggs, DJ	1
Ahn, S; Cho, DG; Cho, WY; Cho, YG; Choi, JR; Hwang, JT; Jang, HS; Kim, J; Kim, KW; Kim, YZ; Roh, KY	1
Avci, A; Erhardt, A; Häussinger, D; Heintges, T; Lörke, J; Sagir, A	1
Andrei, G; De Clercq, E; Snoeck, R	1
Locarnini, S	1
Buti, M; Esteban, R	1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM	1
Leung, N	2
Onishi, T; Sekiyama, T; Tsuji, T	1
Asselah, T; Castelnau, C; Marcellin, P	1
Roche, B; Samuel, D	2
Holý, A; Schinkmanová, M; Votruba, I	1
Asselah, T; Boyer, N; Marcellin, P	1
Sherman, M	1
Lok, AS; Osborn, MK	1
Schiff, ER; Schreibman, IR	1
Feng, B; Wei, L	1
Hou, JL; Zeng, GB	1
Chang, TT; Lai, CL	1
Hollinger, FB; Lau, DT	1
Hadziyannis, SJ	3
Grant, RM; Levy, V	1
Manolakopoulos, S; Papatheodoridis, GV	1
Trautwein, C	1
Aldern, KA; Beadle, JR; Hartline, CB; Hostetler, KY; Kern, ER; Ruiz, JC	1
Benhamou, Y	1
Dienstag, JL; Kreter, B; Wei, LJ; Xu, D	1
Liaw, YF	1
Kang, HM; Kim, CR; Kim, J; Lai, CL; Min, C; Ngai, V; Shin, BS; Yoo, SD; Yuen, JC; Yuen, MF	1
Lok, AS; Tan, J	1
Gish, RG	1
Koike, K; Yotsuyanagi, H	2
Garcia-Gasco, P; Sheldon, J; Soriano, V	1
Arora, G; Keeffe, EB	1
Bifano, M; Grasela, DM; LaCreta, F; Smith, RA; Yan, JH; Zhang, D	1
Buti, M; Elefsiniotis, I; Esteban, R; Gimferrer, M; Jardi, R; Rodriguez-Frias, F; Schaper, M; Tabernero, D	1
Niederau, C	1
Okanoue, T	1
Orito, E	1
Shiryu, H; Suzuki, F; Tanaka, E; Tanaka, Y	1
Abe, H; Chayama, K; Fujimoto, Y; Hatakeyama, T; Hiraga, N; Imamura, M; Kumada, H; Maekawa, T; Mori, N; Ochi, H; Suzuki, F; Takahashi, S; Tsuge, M; Yatsuji, H	1
Clarke, L; Di Bisceglie, A; Gish, RG; Iloeje, UH; Kowdley, KV; Sullivan, SD; Tafesse, E; Veenstra, DL	1
Keeffe, EB	1
Bzowska, A; Hashimoto, M; Hikishima, S; Magnowska, L; Yokomatsu, T	2
Chayama, K; Takahashi, S	1
de Man, RA; Leemans, WF; Ter Borg, MJ	1
Janssen, HL; Reijnders, JG	1
Sánchez-Tapias, JM	1
Bisceglie, A; Di Bisceglie, A; Gish, RG; Kowdley, KV; Spackman, DE; Veenstra, DL	1
Ayoub, WS; Keeffe, EB	1
Girke, J; Manns, MP; Tillmann, HL; Wedemeyer, H; Wiegand, J	1
Flisiak, R; Jaroszewicz, J	1
Kawanaka, T; Shimizu, M; Shintani, N; Wada, T	1
Harrison, TJ; Ijaz, S; Moore, PL; Sloan, RD; Tedder, RS; Teo, CG	1
Bläckberg, J; Duberg, AS; Fischler, B; Friman, S; Karlström, O; Lindh, M; Norkrans, G; Reichard, O; Sangfeldt, P; Söderström, A; Sönnerborg, A; Uhnoo, I; Weiland, O; Wejstål, R; Wiström, J	1
Cheong, JY	1
Yim, HJ	1
de Man, RA; Janssen, HL; Leemans, WF; Niesters, HG; Schalm, SW; van der Eijk, AA	1
Alric, L; Cointault, O; El Kahwaji, L; Izopet, J; Kamar, N; Lavayssière, L; Milioto, O; Rostaing, L; Sauné, K	1
Bzowska, A; Hashimoto, M; Hikishima, S; Magnowska, L; Yatsu, T; Yokomatsu, T	1
Bochtler, M; Breer, K; Bzowska, A; Girstun, A; Hashimoto, M; Hikishima, S; Starón, K; Szczepanowski, RH; Wielgus-Kutrowska, B; Yokomatsu, T	1
Fung, J; Lai, CL; Yuen, MF	1
Beckebaum, S; Cicinnati, VR; Gerken, G; Sotiropoulos, GC	1
Dieterich, DT; Han, SH; Jacobson, IM; Keeffe, EB; Martin, P; Schiff, ER; Tobias, H	1
Holý, A; Otová, B; Votruba, I	1
Campbell, MA; Miller, PS	1
Degertekin, B; Hussain, M; Lok, AS; Oberhelman, K; Tan, J	1
Cross, A; Diva, U; Hann, HW; Hsu, CW; Jeffers, L; Lao-Tan, J; Lesmana, L; Leung, N; Lopez-Talavera, J; Mencarini, K; Min, A; Peng, CY; Sherman, M; Sollano, J; Wilber, R; Yuen, MF	1
García Buey, L; González Mateos, F; Moreno Otero, R	1
Buti, M	2
Calleja, JL; Peñas, B	1
Sarmento E Castro, R; Sheldon, J; Soriano, V	1
González-Diéguez, ML; Rodríguez, M	1
Barreiro, P; García-Samaniego, J; Martín-Carbonero, L	1
McMahon, B; Scott, JD	1
McHutchison, J; Patel, K; Tillmann, H	1
Chien, RN; Liaw, YF	1
Buster, EH; Janssen, HL; Schalm, SW	1
Colombo, M; Lampertico, P	1
de Man, RA; Janssen, HL; Pas, SD; Reijnders, JG; Schutten, M	1
Lampertico, P	2
Amini-Bavil-Olyaee, S; Herbers, U; Luedde, T; Sheldon, J; Tacke, F; Trautwein, C	1
Ham, MY; Holt, C; Saab, S; Stone, MA; Tong, M	1
Dai, YX; Ding, H; Hu, TH; Huang, LH; Jiang, XH; Jiang, YM; Qiu, YW; Zhou, M	1
Angus, PW; Patterson, SJ	1
Borroto-Esoda, K; Curtis, M; Miller, MD; Qi, X; Zhu, Y	1
Drach, JC; Ksebati, B; Mhaske, SB; Prichard, MN; Zemlicka, J	1
Buti, M; Córdoba, J; Esteban, R; García-Martínez, R; Les, I; Quintana, M	1
Buffet, C	1
Gong, QM; Han, Y; Huang, LH; Jin, GD; Kong, XF; Li, J; Lin, ZM; Liu, CM; Lu, ZM; Yang, S; Yu, DM; Zhang, DH; Zhang, XX	1
Cong, M; Jia, J; Li, H; Liu, T; Ma, H; Ou, X; Ren, J; Wang, B; Wang, P; Wang, X; You, H	1
Chung, YH; Kim, KM; Lee, HC; Lee, YS; Lim, YS; Shim, JH; Suh, DJ	1
Cheong, JY; Cho, SW; Hong, SP; Kim, SO; Koh, KH; Lee, MH; Yoo, WD	1
Ahn, SH; Chon, CY; Han, KH; Hong, SP; Kim, DY; Kim, HJ; Kim, JK; Lee, CK; Lee, HW; Lee, JM; Lee, KS; Nguyen, T; Paik, YH; Park, JY	1
Lok, AS; McMahon, BJ	1
Barreiro, P; Fernández, JV; Labarga, P; Medrano, J; Soriano, V; Tuma, P; Vispo, E	1
Hayashi, N; Hiramatsu, N; Hosui, A; Ishida, H; Kanto, T; Kurashige, N; Miyagi, T; Mochizuki, K; Ohkawa, K; Oze, T; Takehara, T; Tatsumi, T; Yakushijin, T	1
Lin, Q; Zhang, DZ	1
Byun, KS; Choe, WH; Hong, SP; Ji, SI; Jung, YK; Kim, BK; Kim, JH; Kim, KH; Kim, SO; Ko, SY; Kwon, SY; Lee, CH; Yeon, JE	1
Bochtler, M; Breer, K; Bzowska, A; Chojnowski, G; Czapinska, H; Girstun, A; Hashimoto, M; Hikishima, S; Narczyk, M; Staroń, K; Wielgus-Kutrowska, B; Yokomatsu, T	1
Funk, A; Helm, M; Olotu, C; Rockstroh, JK; Schildgen, O; Sirma, H; Zöllner, B	1
Gervain, J; Horváth, G; Hunyady, B; Makara, M; Pár, A; Szalay, F; Telegdy, L; Tornai, I	1
Han, KH; Kim, CR; Kim, HR; Kim, J; Lai, CL; Um, SH; Yoon, SK; Yuen, MF	1
Bzowska, A; Glavas-Obrovac, L; Hashimoto, M; Hikishima, S; Magnowska, L; Suver, M; Yokomatsu, T	1
Wei, N; Wu, XF; Yang, F	1
Marcellin, P; Piratvisuth, T; Sung, J	1
Marcellin, P; Perrillo, RP	1
Buti, M; Deterding, K; Hansen, BE; Janssen, HL; Petersen, J; Reijnders, JG; Santantonio, T; van Bömmel, F; Wedemeyer, H; Zoulim, F	1
Breer, K; Bzowska, A; Glavas-Obrovac, L; Hashimoto, M; Hikishima, S; Magnowska, L; Suver, M; Wielgus-Kutrowska, B; Yokomatsu, T	1
Deinhardt, S; Sauerbrei, A; Wutzler, P; Zell, R	1
Aldern, KA; Beadle, JR; Hostetler, KY; Trahan, J; Valiaeva, N	1
Bucko, M; Gemeiner, P; Lacík, I; Mislovicová, D; Tkác, J; Vikartovská, A	1
Crescentini, F; Curvelo, LA; de Miranda, MP; Dos Santos, RG; Ferreira, FY; Genzini, T; Guirro, TG; Mota, LT; Noujaim, HM; Pedrosa, C; Pereira, JR; Salomão, P	1
Chee, GM; Poordad, F	1
Jiang, L; Yan, LN	1
Hu, P; Lin, Q; Ren, H; Shi, XF; Wang, ZY; Zeng, WQ; Zhang, DZ; Zhou, Z	1
Bao, H; Furman, PA; Korba, B; Micolochick Steuer, HM; Murakami, E; Niu, C; Tolstykh, T	1
Chien, RN	1
Chen, H; Li, T; Shen, J; Wu, B	1
Chan, TM; Choy, BY; Tang, CS; Yap, DY; Yuen, MF; Yung, S	1
Choi, JJ; Jang, H; Kim, J; Park, H; Son, Y	1
Chen, L; Liu, Y; Ren, X; Si, L; Wang, Y; Xu, D; Xu, T; Xu, Z; Zhao, J; Zhong, Y	1
Brereton, IM; Cesnek, M; de Jersey, J; Guddat, LW; Hocková, D; Holý, A; Keough, DT; Krecmerová, M; Naesens, L; Winzor, DJ	1
Einarson, TR; Heathcote, EJ; Kowgier, M; Krahn, M; Nishikawa, Y; Pham, B; Sherman, M; Tomlinson, G; Ungar, WJ; Wong, DK; Woo, G	1
Coffin, CS; Michalak, TI; Mulrooney-Cousins, PM; Peters, MG; Roberts, JP; Terrault, NA; van Marle, G	1
Chung, YH; Heo, NY; Lee, HC; Lee, YS; Lim, YS; Suh, DJ	1
Cho, YK; Jeon, WK; Kim, BI; Kim, HJ; Park, DI; Park, JH; Sohn, CI	1
de Man, RA; de Vries-Sluijs, TE; Hansen, BE; Hoepelman, AI; Janssen, HL; Mulder, JW; Pas, SD; Prins, JM; Reijnders, JG; Richter, C; Schutten, M; van der Ende, ME; Zaaijer, HL	1
Bentley, A; Dakin, H; Dusheiko, G	1
Dakin, H; Fidler, C; Harper, C	1
Belvisi, V; Cenfra, N; Cimino, G; Del Borgo, C; Lichtner, M; Marocco, R; Mastroianni, CM; Mecarocci, S; Rago, A	1
Akuta, N; Arase, Y; Hirakawa, M; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Saitoh, S; Sezaki, H; Suzuki, F; Suzuki, Y; Yatsuji, H	1
Boroń-Kaczmarska, A; Cianciara, J; Flisiak, R; Gładysz, A; Halota, W; Juszczyk, J; Kryczka, W; Malkowski, P; Pawlowska, M; Simon, K	1
Einecke, D	1
Ahn, SH; Chon, CY; Han, KH; Kim, DY; Lee, JM; Lee, MH; Park, JY; Ryu, HJ	1
Amini-Bavil-Olyaee, S; Herbers, U; Luedde, T; Tacke, F; Trautwein, C	1
Chotiyaputta, W; Ditah, FA; Goodwin, D; Lok, AS; Peterson, C	1
Jiang, Y; Li, W; Liu, J; Niu, J; Sun, P; Xin, G; Xu, D; Yan, H; Yu, L; Zhang, H	1
de la Cruz-Lombardo, J; Jiménez-Pérez, M; Lozano-Rey, JM; Mongil Poce, L; Rodrigo-López, JM; Sáez-Gómez, AB	1
Brost, S; Eisenbach, C; Schnitzler, P; Stremmel, W	1
Kern, ER; Prichard, MN	1
Bourlière, M; Kahloun, A; Zoulim, F	1
Benhamou, Y; Pais, R	1
Marcellin, P	1
Abuduheilili, X; Dong, JP; Hou, CS; Jiao, XJ; Li, T; Li, XG; Liu, BM; Sun, XW; Wang, YH; Xu, J; Yan, CH; Yan, L; Yang, JX; Zhuang, H	1
Chen, L; Ji, D; Li, X; Liu, Y; Wang, C; Wang, H; Xin, S; Xu, D; Zhong, Y; Zoulim, F	1
Bartels, M; Berg, T; Hartmann, J; Jonas, S; Karlas, T; Maier, M; Mössner, J; Tillmann, HL; Weimann, A; Wiegand, J	1
Janssen, HL; Rijckborst, V; Sonneveld, MJ	1
Janssen, HL; Sonneveld, MJ	1
Papatheodoridis, GV	1
Zoulim, F	1
Mallet, V; Pol, S; Vallet-Pichard, A	1
Bettocchi, D; Consales, G; Durval, A; Luzzio, MG; Zamidei, L	1
Chung, GE; Hwang, SY; Jeong, JB; Jung, YJ; Kim, BG; Kim, D; Kim, HY; Kim, W; Kim, YJ; Lee, HS; Lee, JH; Lee, KL; Yoon, JH	1
Akarca, US; Berg, T; Buti, M; Chang, TT; Frederick, D; Horban, A; Kitrinos, K; Kwan, P; Lee, CM; Liaw, YF; Mondou, E; Papatheodoridis, GV; Peschell, K; Prieto, M; Rousseau, F; Schiff, ER; Sheen, IS; Suet-Hing Wong, F; Wang, C	1
Ikeda, F; Kobashi, H; Yamamoto, K	1
Akaike, J; Arakawa, T; Karino, Y; Kimura, M; Kuwata, Y; Nakajima, T; Ohmura, T; Ozeki, I; Sato, T; Toyota, J	1
Hosaka, T; Kumada, H; Suzuki, F	1
Ahn, SH; Cho, SW; Choi, SH; Hahn, JS; Han, KH; Hong, SP; Kim, SO; Shin, SK	1
Chaung, KT; Garcia, RT; Ha, NB; Levitt, BS; Nguyen, HA; Nguyen, KK; Nguyen, MH; Trinh, HN	1
Chang, TT; Cheng, PN; Liu, WC; Tsai, HW; Wu, IC; Young, KC	1
Guan, Q; Liu, W; Zhao, J; Zhao, P	1
Beadsworth, MB; Pennell, A; Phillips, M; Ratcliffe, L; Vilar, FJ	1
Liu, T; Wang, Y; Zhang, C	1
Dai, J; Ji, D; Li, L; Li, X; Liu, Y; Ren, X; Wang, C; Wang, L; Wong, VW; Xu, D; Xu, Z; Yao, Z; Zhang, L; Zhong, Y; Zoulim, F	1
Beebe, S; Bialkowska, J; Brown, RS; Cheinquer, H; Cooney, E; Jeffers, L; Leung, N; Liaw, YF; Myers, RP; Peng, CY; Raptopoulou-Gigi, M; Sarin, SK; Tang, S; Tanwandee, T; Tsai, N	1
Harbord, N	1
Cong, M; Jia, J; Liu, T; Ma, H; Ou, X; Wang, B; Wang, P; Wang, Q; Wu, X; You, H	1
Tornai, I	1
Minami, M; Okanoue, T	2
Chan, HL; Ge, S; Guo, W; Hu, J; Huang, X; Jiang, J; Jiang, Z; Liang, Y; Liu, Z; Su, M; Wong, VW; Xie, R; Zhu, M	1
Andreoni, M; Bertoli, A; Ceccarelli, L; Perno, CF; Salpini, R; Sarrecchia, C; Sordillo, P; Svicher, V; Volpi, A	1
Guo, YB; Hou, JL; Peng, J; Sun, J; Wang, ZH; Yan, L; Yang, J; Zhou, B	1
Alberti, A; Bortoletto, G; Campagnolo, D; Franceschini, L; Marcolongo, M; Mirandola, S	1
Benetti, S; Cassino, L; Fay, F; Quarleri, J; Tanno, H	1
Cho, EJ; Hwang, SY; Jang, ES; Kim, CY; Kim, YJ; Kwak, MS; Lee, CH; Lee, HS; Lee, JH; Yang, HJ; Yoon, JH; Yu, SJ	1
Boucher, CA; Hansen, BE; Janssen, HL; van Vuuren, AJ; Zoutendijk, R	1
Chan, HL; Chan, HY; Locarnini, SA; Tse, CH; Wong, GL; Wong, VW; Yuen, LK	1
Antinori, S; Corbellino, M; Dodero, A; Foschi, A; Mazzocchi, A; Micheli, V; Milazzo, L; Montefusco, V; Zehender, G	1
Block, TM; Clearfield, E; Cuconati, A; Goddard, C; Guo, H; Mills, C; Morrey, JD; Motter, NE; Xiao, T; Xu, X; Yu, W; Zhao, K	1
Chen, SJ; Fan, WB; Li, Q; Li, WW; Liu, L; Xie, SS; Yang, X; Yu, JH	1
Do, ST; Garcia, RT; Nguyen, HA; Nguyen, KK; Nguyen, MH; Nguyen, TT; Sheen, E; Tran, P; Trinh, HN	1
Giles, M; Sasadeusz, J; Visvanathan, K	1
Hu, HD; Hu, P; Liu, JY; Ren, H; Sheng, YJ; Tong, SW; Zhang, DZ	1
Chan, HL; Chan, HY; Ong, A; Tse, CH; Wong, GL; Wong, VW	1
Cho, YS; Choi, JW; Kim, KA; Kwak, MS; Lee, CK; Lee, JS; Park, BK; Suh, JH; Won, SY	1
Jang, JS; Jang, MK; Kim, DJ; Kim, HS; Kim, HY; Kim, KH; Lee, JH; Lee, MS; Park, CK; Park, JW; Seo, DD; Shin, WG	1
Razonable, RR	1
Hong, JH; Kim, E; Shen, GH	1
Bowlin, TL; Chou, S; Marousek, G	1
Cheong, JY; Cho, SW; Hong, SP; Kim, SO; Kim, SS; Lee, D; Lee, MH	1
Berg, T; Brown, A; Buggisch, P; Buti, M; Janssen, HL; Lampertico, P; Lutgehetmann, M; Petersen, J; Ratziu, V; Sarrazin, C; Schollmeyer, J; Sterneck, M; Wedemeyer, H; Zoulim, F	1
Lee, SS; Sherman, M	1
Hong, JH; Kim, E; Li, H; Yoo, JC	1
Bozdayi, AM; Cinar, K; Gokahmetoglu, S; Güven, K; Idilman, R; Karatayli, E; Karatayli, SC; Yurdaydin, C	1
Li, XJ; Shu, X; Xu, QH; Zhu, JY	1
Campanale, F; D'Addiego, G; Fazio, V; Giammario, A; Scotto, G	1
Cao, Z; Chen, X; Jin, Y; Liu, Y; Ma, B; Ma, L; Wu, H; Yu, H; Zhang, H; Zhang, Y; Zheng, Y	1
Dalekos, GN; Tillmann, HL; Zachou, K	1
García-Alonso, FJ; Martín-Mateos, RM; Moreira Vicente, V	1
Cha, JM; Jeon, JW; Joo, KR; Kim, S; Lee, JI; Lim, JU; Lim, K; Park, JJ; Shin, HP	1
Guo, HH; Ji, SW; Jiao, J; Li, Y; Si, QT; Wang, JB; Xu, Y; Zhang, MH; Zhang, YG; Zhao, P; Zhou, CY	1
Bohn, K; Hamprecht, K; Heim, A; Hoffmann, D; Hofmann, J; Jahn, G; Sauerbrei, A; Schnitzler, P; Weissbrich, B; Wutzler, P; Zell, R	1
Brunetto, MR; Janssen, HL; Sonneveld, MJ	1
Cox, N; Tillmann, H	1
Kim, YJ; Lee, HS; Lee, JH; Yang, HJ; Yoon, JH	1
Fontana, RJ; Singal, AK	1
Klener, P; Maswabi, B; Panova, N; Pohl, R; Rejman, D; Rosenberg, I	1
Fujimori, M; Kumada, T; Sone, Y; Tada, T; Toyoda, H	1
Heo, NY; Lee, HC; Lee, TH; Lim, YS; Shim, JH; Suh, DJ	1
Chang, J; Chen, PJ; Han, SY; Hsiao, CC; Liu, WH; Wu, JY; Yeh, SH	1
Bunchorntavakul, C; Chen, W; Hu, KQ; Pan, CQ; Reddy, KR; Yu, AS	1
Chang, MH; Changchien, CS; Chen, CH; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Wang, JH	1
Gervain, J; Horváth, G; Hunyady, B; Makara, M; Pár, A; Szalay, F; Telegdy, L; Tornai, I; Ujhelyi, E	1
Ridruejo, E; Silva, MO	1
Lee, D; Lee, HC; Lee, JY; Lee, YS; Lim, YS; Shim, JH; Suh, DJ	2
Han, T; Li, J; Li, Y; Liu, L; Xiao, SX; Xing, J	1
Lee, WM; Tujios, SR	2
Ahn, SH; Chon, CY; Han, KH; Kim, DY; Lee, JM; Lee, MH; Park, JY; Ryu, HJ; Son, CY	1
Cardozo, M; Chen, X; Deignan, J; Fu, Z; Guimaraes, C; Heath, J; Jeffries, S; Johnstone, S; Kayser, F; Kopecky, DJ; Lai, S; Li, S; Mihalic, J; Min, X; Shen, S; Shen, W; Thibault, S; Walker, N; Wang, Z; Xu, H	1
Lampertico, P; Liaw, YF	1
Baqai, S; Clark, MD; Gish, RG; Kane, SD; Mangahas, MF; Shaw, RE	1
Fernandes, CA; Gomes, Sde A; Mello, FC	1
Chae, HB; Choi, YH; Han, JH; Kim, MJ; Lee, HS; Park, SM; Seo, EG; Yoon, SM; Youn, SJ	1
Lampertico, P; Pol, S	1
Akriviadis, E; Antoniadis, N; Cholongitas, E; Goulis, I; Papanikolaou, V; Vasiliadis, T	1
Akarca, US; Carosi, G; Cohen, D; Gadano, A; Habersetzer, F; Llamoso, C; Lok, AS; Lovegren, M; Sievert, W; Trinh, H; Wong, D	1
Cho, MH; Cho, SM; Choe, BH; Chu, M; Kwon, S; Lee, WK	1
Almasio, PL; Bertino, G; Brandolino, N; Bruno, S; Caroleo, B; Cosco, L; Di Marco, V; Foti, G; Frugiuele, P; Galdieri, A; Madonia, S; Montalto, G; Portelli, V; Russello, M; Sapienza, M; Scifo, G; Siciliano, R; Spadaro, A; Stroffolini, T; Surace, L	1
Diao, S; Ha, M; Huang, C; Huang, Z; Lin, M; She, H; Shen, L; Shen, W; Sun, L; Wu, J; Zhang, G	1
Alfieri, A; Boni, C; Brancaccio, G; Colombo, M; Ferrari, C; Gaeta, GB; Giuberti, T; Laccabue, D; Lampertico, P; Missale, G; Pesci, M; Schivazappa, S; Viganò, M	1
Akin, MS; Doğan, ÜB; Gümürdülü, Y; Kara, B; Soylu, A	1
Huang, Y; Wang, J; Wang, M	1
Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Snoeck, R; Tichý, T	1
Bozdayi, AM; Cevik, E; Idilman, R; Kabaçam, G; Karatayli, E; Karatayli, SC; Seven, G; Yakut, M; Yurdaydin, C	1
Huang, L; Li, T; Wang, C; Xu, D; Zhao, P	1
Huh, W; Jung, JA; Kim, JR; Kim, SR; Kim, TE; Ko, JW; Lee, SY	1
Ahmed, A; Chaung, K; Cheung, R; Nguyen, HA; Nguyen, MH; Trinh, HN; Wong, CR; Yip, B	1
Baxa, DM; Borroto-Esoda, K; Chappell, BJ; Golembieski, A; Gordon, SC; Jovanovich, J; Kizy, A; Krishnan, PV; Sharif, O; Shetron-Rama, L; Snow-Lampart, A; Thekdi, AD	1
Alberti, A; Campagnolo, D; Erne, EM; Mirandola, S; Romualdi, C; Rossi, C; Sebastiani, G; Tempesta, D; Vario, A; Velo, E	1
Akbal, E; Akin, E; Alkan, E; Ataseven, H; Aygün, C; Başar, O; Baykal, O; Coban, S; Demir, M; Gülşen, MT; Ibiş, M; Koçkar, MC; Köklü, S; Köksal, AŞ; Küçükazman, M; Nadir, I; Ozdil, K; Pürnak, T; Tuna, Y; Yildirim, B; Yüksel, I; Yüksel, O	1
Baak, BC; Bakker, CM; Beuers, UH; Brouwer, JT; Buster, EH; Drenth, JP; Honkoop, P; Janssen, HL; Kerbert-Dreteler, MJ; Koek, GH; Tan, AC; van der Spek, BW; van Erpecum, KJ; van Hoek, B; van Nieuwkerk, KM; van Soest, H; Vrolijk, JM	1
Cheng, D; Gong, GZ; He, B; Jiang, YF; Li, NP; Ma, J	1
Cheong, JY; Cho, SW; Hong, SP; Kim, SO; Kim, SS	1
Andou, Y; Hisanaga, Y; Kanamori, A; Kiriyama, S; Kumada, T; Niinomi, T; Tada, T; Tanaka, J; Tanikawa, M; Toyoda, H; Yamamoto, K; Yasuda, S	1
Cholongitas, E; Papatheodoridis, GV	1
Hu, KQ; Pan, CQ; Tsai, N	1
Cho, EJ; Cho, Y; Chung, KH; Jeong, SH; Jin, E; Kim, CY; Kim, JW; Kim, YJ; Lee, DH; Lee, HS; Lee, JH; Yoon, JH; Yu, SJ	1
Choi, DJ; Jung, YK; Kim, JH; Kim, YS; Ku, YS; Kwon, OS	1
Ahn, SH; Hong, SP; Hwang, SG; Kim, BH; Kim, HS; Kim, IH; Kim, JH; Lee, JI; Lee, JM; Lee, JW; Lee, SH; Lee, SJ; Park, SJ; Park, YM; Seo, YS; Yim, HJ; Yoon, EL	1
Bahrami, S; Chevaliez, S; Grare, M; Hézode, C; Pawlotsky, JM	1
Buti, M; Petersen, J	1
Fu, SY; Huang, G; Lau, WY; Pan, ZY; Shen, F; Wu, MC; Yang, Y; Zhou, WP	1
Coffin, CS; Fung, SK; Ma, MM	1
Choi, BS; Choi, SR; Chung, BH; Hong, YA; Kim, YS; Park, CW; Park, HS; Sun, IO; Yang, CW	1
Baik, SK; Chae, HB; Hong, SP; Kim, CW; Kim, JH; Kim, MY; Kim, YS; Lee, CD; Lee, JI; Lee, JW; Lee, MS; Park, CK; Park, SH; Seo, YS; Um, SH; Yim, HJ; Yoon, EL	1
Colle, I; Gamil, M; Horsmans, Y; Hulstaert, F; Nevens, F; Schwierz, C; Thiry, N; Van de Sande, S	1
Arakawa, T; Hige, S; Karino, Y; Kimura, M; Kuwata, Y; Nakajima, T; Ohmura, T; Ozeki, I; Sato, T; Toyota, J	1
Baietto, L; Boglione, L; Burdino, E; Cariti, G; Cusato, J; D'Avolio, A; De Rosa, FG; Di Perri, G; Ghisetti, V; Gregori, G	1
Cui, YJ; Song, ZL; Teng, DH; Zheng, H; Zheng, WP	1
Buti, M; Casado, MA; Lozano, V; Oyagüez, I	1
Han, SS; Hong, G; Kong, SY; Lee, KB; Lee, KW; Park, KU; Park, SJ; Suh, KS; Yi, NJ	1
Fadda, V; Maratea, D; Messori, A; Trippoli, S	1
Beggel, B; Kaiser, R; Neumann-Fraune, M; Pfister, H; Verheyen, J	1
Chen, EQ; Liu, K; Lu, JJ; Ma, YJ; Tang, H; Wang, J	1
Bonino, F; Brunetto, MR; Caputo, A; Coco, B; Espinos, B; Iannazzo, S; Latour, A; Rossetti, F	1
Acurcio, Fde A; Almeida, AM; Andrade, EI; Araújo de Oliveira, GL; Brandão, CM; Carmo, RA; Cherchiglia, ML; Silva, AL	1
Amarapurkar, DN; Patel, N	1
Brown, RS; Chang, MS; Emond, JC; Guarrera, JV; Heese, S; Olsen, SK; Pichardo, EM; Stiles, JB	1
Brown, RS; Brubaker, WD; Chang, MS; Emond, JC; Guarrera, JV; Olsen, SK; Pichardo, EM; Rosenthal-Cogan, L; Stiles, JB	1
Acalovschi, M; Arama, V; Bjork, S; Kamar, D; Klauck, I; Leblebicioglu, H; Lescrauwaet, B; Marcellin, P; Mauss, S; Morais, E; Sieklucki, J; Simon, K; Usluer, G; Zarski, JP; Zeuzem, S	1
Alteri, C; Andreoni, M; Angelico, M; Cento, V; De Sanctis, GM; Gubertini, G; Micheli, V; Parruti, G; Perno, CF; Pollicita, M; Romano, S; Salpini, R; Sarrecchia, C; Svicher, V; Visca, M	1
Ahn, SH; Baartarkhuu, O; Chon, CY; Han, KH; Kim, BK; Kim, DY; Kim, JK; Kim, KS; Kim, SU; Park, JY; Park, MS	1
Chan, AC; Chan, SC; Cheung, C; Cheung, TT; Chok, KS; Fan, ST; Fung, J; Lai, CL; Lo, CM; Seto, WK; Sharr, W; Yuen, MF	1
Chen, Q; He, LL; Wang, JC	1
Deng, JY; He, FQ; Li, GL; Li, JY; Li, Q; Pan, QR; Qin, Y; Xu, XH	1
Fontana, RJ; Kuo, YF; Salameh, H; Singal, AK	1
Terrault, N	1
Delaney, W; Furman, P; Hu, J; Jones, SA; Murakami, E	1
Goyal, N; Gupta, S; Kumar, A; Taneja, S; Wadhawan, M	1
Mendes-Correa, MC; Núñez, M	1
Horváth, G	1
Gulland, A	1
Asselah, T; Marcellin, P	1
Šperl, J	1
Alp, A; Aydoğan, S; Balaban, Y; Ergünay, K; Hasçelik, G; Simşek, H; Tatar, G; Us, D	1
Buğdacı, MS; Sayan, M	1
Ahn, SH; Cho, M; Han, KH; Kim, JA; Kweon, YO; Lai, CL; Lee, J; Lee, JW; Lee, KS; Park, NH; Sohn, JH; Um, SH; Yoon, SK; Yuen, MF	2
Kim, DG; Kim, IH; Kim, SH; Kim, SW; Lee, S; Lee, SO; Lee, ST; Seo, SY; Sohn, JY	1
Cai, FJ; Ding, JG; Du, QW; Fu, RQ; Hong, L; Sun, QF; Wu, YH; Zhou, QQ	1
Akkoyunlu, Y; Ceylan, B; Eren, G; Fincanci, M; Muderrisoglu, C; Tozalgan, U; Yardimci, C	1
Cho, Y; Cho, YY; Choi, WM; Kim, CY; Kim, YJ; Lee, DH; Lee, HS; Lee, JH; Lee, M; Lee, YB; Yoo, JJ; Yoon, JH; Yu, SJ	1
Hu, H; Hu, P; Liu, J; Peng, H; Ren, H; Tang, H; Tong, S; Yang, M; Yin, W	1
Chen, JY; Hu, JH; Jia, HY; Li, LJ; Lian, JS; Lu, YF; Xiang, DR; Yang, YD; Yu, L; Zeng, LY; Zhang, YM; Zheng, L	1
Halfon, P; Joly, H; Khiri, H; Ouzan, D; Pénaranda, G; Pironti, A	1
Chen, RC; Dai, XH; Fan, XG; Huang, Y; Huang, ZB; Li, N; Li, WT; Yi, PP; Zhang, BX; Zhao, SS; Zhou, RR	1
Cholongitas, E; Papatheodoridis, G; Pipili, C	1
Arama, V; Bjork, S; Bludzin, W; Habersetzer, F; Jinga, M; Kamar, D; Klauck, I; Leblebicioglu, H; Lescrauwaet, B; Morais, E; Niederau, C; Simon, K; Ulusoy, S; Vermehren, J; Zarski, JP; Zeuzem, S	1
Acurcio, Fde A; Almeida, AM; Andrade, EI; Brandão, CM; Cherchiglia, ML; Oliveira, GL; Silva, AL	1
Chen, Z; Li, M; Liu, Z; Wu, J; Xu, G; Zhang, Q	1
Calvaruso, V; Craxì, A	1
Lampertico, P; Mangia, G; Viganò, M	2
Colombo, M; Della Corte, C; Triolo, M	1
Esteban, R; Pérez-Cameo, C; Pons, M	1
Bowlin, TL; Chou, S; Komazin-Meredith, G; Williams, JD	1
Deng, Z; Li, B; Li, Z; Liu, S; Wang, C	1
Chung, RT; Fishman, JA; Wright, AJ	1
Wang, X; Wang, Y; Xiong, Y; Zhang, C; Zhu, Y	1
Gao, L; Li, J; Nguyen, MH; Trinh, HN	3
Cai, SH; Jiang, YG; Lv, FF; Peng, J; Zhang, YH	1
Price, J	1
Strasser, SI	1
Kang, Y; Lin, X; Liu, H; Lu, M; Mao, R; Qin, Y; Wang, J; Zhang, J; Zhang, Y; Zhu, H	1
Cho, JH; Choi, JY; Huh, S; Kang, YJ; Kim, CD; Kim, HK; Kim, JS; Kim, YL; Kwon, O; Lim, JH; Park, GY; Park, SH	1
Doss, W; El Din, SS; Hassan, K; Maklad, S; Zeid, AA	1
Gervain, J; Horváth, G; Hunyady, B; Lengyel, G; Makara, M; Pár, A; Szalay, F; Telegdy, L; Tornai, I	1
Hu, H; Hu, P; Liu, F; Ren, H; Wang, X; Wei, F; Zhang, D	1
Bradshaw, D; Danta, M	1
Błudzin, W; Dziambor, A; Goryszewski, D; Kolasa, K; Lescrauwaet, B; Postawa-Kłosińska, B; Sieklucki, J; Simon, K	1
Hu, X; Jiang, Y; Wang, Q; Zhang, L; Zhao, P	1
Coppola, N; Filippini, P; Martini, S; Pisaturo, M; Sagnelli, C; Sagnelli, E	1
Lee, SS; Sadler, MD	1
Cainelli, F; Comparcola, D; Della Corte, C; Nobili, V; Vento, S	1
Tang, CM; Yau, TO; Yu, J	1
De Vincentis, A; Dell'Unto, C; Galati, G; Gallo, P; Picardi, A; Solmone, MC; Vespasiani-Gentilucci, U; Vincenti, D	1
Cagatay, A; Ceylan, B; Erdem, L; Gokturk, K; Gunduz, A; Karaosmanoglu, H; Kocak, F; Mete, B; Ozaras, R; Ozgunes, N; Senates, E; Tabak, F	1
Gao, Y; Ke, W; Liu, L; Yang, Y; Ye, X; Zhang, C; Zhou, S	1
Hou, FQ; Huo, N; Li, F; Li, MR; Wang, QH; Xi, HL; Xu, XY; Zhang, XX	1
Akriviadis, E; Antoniadis, N; Cholongitas, E; Fouzas, I; Goulis, I; Imvrios, G; Papanikolaou, V	1
Kim, JH; Kim, KH; Park, ES; Park, YK	1
Lei, Y; Liu, JY; Xu, H; Zeng, T; Zhong, S; Zhou, Z	1
Ridruejo, E	1
Chen, L; Li, X; Liu, Y; Wang, Y; Xin, S; Xu, D; Zhang, XX; Zhao, P	1
Baik, SK; Chae, HB; Hong, SP; Kim, CW; Kim, JH; Kim, MY; Kim, YS; Lee, CD; Lee, HJ; Lee, JI; Lee, JW; Lee, MS; Park, CK; Park, SH; Seo, YS; Suh, SJ; Um, SH; Yim, HJ	1
Berg, T; van Bömmel, F	1
Gerlich, WH	1
Locarnini, S; Warner, N	1
Beggel, B; Kaiser, R; Neumann-Fraune, M; Obermeier, M	1
Akuta, N; Arase, Y; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Mineta, R; Saitoh, S; Sezaki, H; Suzuki, F; Suzuki, Y; Watahiki, S	1
Afdhal, NH; Bonder, A; Lau, D; Patwardhan, VR; Sengupta, N	1
Shan, C; Wu, P; Yin, GQ	1
Ahn, H; Cho, EJ; Cho, H; Cho, Y; Cho, YY; Choi, WM; Kim, CY; Kim, YJ; Lee, DH; Lee, HS; Lee, JH; Lee, M; Lee, YB; Yoo, JJ; Yoon, JH; Yu, SJ	1
Arends, P; Buti, M; Colombo, M; Dalekos, GN; Esteban, R; Galanis, K; Gatselis, N; Goulis, J; Hansen, BE; Idilman, R; Janssen, HL; Keskın, O; Lampertico, P; Mangia, G; Manolakopoulos, S; Papaioannou, C; Papatheodoridis, GV; Savvidou, S; Sypsa, V; Yurdaydin, C	1
Chen, X; Gao, W; Li, D; Peng, J; Wen, F; Xia, J; Xu, C; Xu, M; Yao, Z	1
Hong, JH; Kim, E; Kim, S	1
Alcantara, L; Burak, KW; Coffin, CS; Klein, P; Myers, RP; Pang, JX; Rezaeeaval, M	1
Ahn, DG; Baek, EK; Cho, HJ; Chung, HW; Kim, HJ; Kwon, JC; Lee, H; Lee, JJ; Ze, E	1
Brocchieri, A; Castelli, F; Colombo, M; Facchetti, F; Fugazza, A; Lampertico, P; Mangia, G; Spinetti, A; Viganò, M; Zaltron, S	1
Petersen, J	1
Fan, H; Fan, Y; Ge, Y; Li, D; Liu, X; Liu, Z; Lyu, W; Yang, H; Zhou, B	1
Papatheodoridis, GV; Vlachogiannakos, J	1
Invernizzi, F; Lampertico, P; Viganò, M	1
Andrade, JR; Barros, LM; Bertolini, DA; Carrilho, FJ; Conde, SR; de Araújo, LV; Ferreira, AC; Ferreira, AS; Galvan, J; Gomes-Gouvêa, MS; Kliemann, DA; Kunyoshi, AS; Leite, AG; Lyra, AC; Mendes-Corrêa, MC; Nastri, AC; Oikawa, MK; Piccoli, LZ; Pinho, JR; Rezende, RE; Soares, MC; Teixeira, R	1
Choudhary, NS; Goja, S; Menon, PB; Mohanka, R; Rastogi, A; Saigal, S; Saraf, N; Soin, AS	1
Cho, Y; Kim, YJ; Lee, HS; Lee, JH; Yoon, JH; Yu, SJ	1
Hong, SP; Hwang, SG; Jang, ES; Jeong, SH; Kang, SK; Lee, JH; Park, SJ	1
Ha, FS; Han, T; Liu, H; Liu, L; Nie, CY; Zhang, Q	1
Caccuri, F; Caruso, A; Castelli, F; De Francesco, MA; Gargiulo, F; Giagulli, C; Spinetti, A; Zaltron, S	1
Ouyang, R; Ye, X	1
Alvey, N; Chan, EY; Cohen, E; Eswaran, S; Fayek, SA; Fleetwood, VA; Hertl, M; Shah, N; Singer, GA; Zielsdorf, S	1
An, J; Byun, KS; Kim, YJ; Kwon, SY; Lee, HC; Lee, YS; Lim, YS; Yoo, BC	1
Cai, H; Chen, JY; Ding, F; Hu, JH; Jia, HY; Li, LJ; Lian, JS; Lu, YF; Xiang, DR; Yang, YD; Yu, GD; Yu, L; Zeng, LY; Zhang, YM; Zheng, L	1
Ahn, SH; Choi, SH; Chon, YE; Han, KH; Hong, SP; Jin, B; Kim, DY; Kim, KH; Kim, ND; Kim, S; Nam, CM; Park, JH; Park, JY	1
Chen, L; Huang, Y; Mao, R; Qi, X; Qin, Y; Wang, J; Zhang, J	1
Akın, MS; Doğan, ÜB; Öztürk, AB; Sayan, M; Yalaki, S	1
Arora, SK; Bhattacharyya, R; Chakraborti, A; Chawla, YK; Das, A; Dhiman, RK; Duseja, A; Kapil, S; Sharma, BK; Singla, B	1
Chong, YT; Gao, ZL; Huang, MX; Jie, YS; Li, XY; Li, ZY; Lin, GL; Wu, YK; Xie, DY; You, X; Zhang, M	1
Fong, TL; Hsieh, MJ; Khemichian, S; Kim, J; Limurti, J; Zhang, SR	1
Bang, SJ; Jeong, ID; Jung, SW; Kim, BG; Kim, CJ; Kim, EH; Kim, JH; Kim, MH; Lee, BU; Park, BR; Park, JH; Park, NH; Shin, JW; Sung, SJ	1
Chen, Y; Duan, Z; Liu, S; Lu, F; Wang, Y; Zheng, S; Zhou, L	1
Cui, X; Dai, J; Huang, M; Jiang, X; Li, J; Ning, H; Su, F; Yang, S	1
Liu, Y; Qiu, P; Wang, G; Wen, J; Wen, P; Xiao, X; Xu, L; Zhou, SF	1
Lai, J; Wang, J; Wang, X; Yang, N; Yuan, G; Zhang, H; Zhou, Y	1
Cai, S; Jiang, Y; Lv, F; Peng, J; Yu, T; Zhang, Y	1
Amano, M; Aoki, M; Haraguchi, K; Imoto, S; Kohgo, S; Kumamoto, H; Kuwata-Higashi, N; Mitsuya, H; Tokuda, R	1
Jansen, L; Kootstra, NA; Reesink, HW; Takkenberg, RB; van Dort, KA; Zaaijer, HL	1
Ahn, SH; Chong, Y; Kang, HS; Kim, BK; Kim, DH; Kim, KH; Lee, AR; Park, ES; Park, S; Park, YK; Rhee, JK; Shin, GC; Yang, SI	1
Chu, CK; Konreddy, AK; Rawal, RK	1
Demirhan, YE; Gultekin, G; Isal, B; Khodor, H; Ozaras, R; Unal, UK; Yetim, N	1
Amani, A; Niederau, C; Thiel, A	1
Hwang, SG; Jang, MK; Jeong, SH; Jung, YK; Kim, BH; Kim, HS; Kim, IH; Kim, JH; Kim, JW; Kim, SG; Kim, TY; Kim, YS; Lee, JI; Lee, JW; Lee, SH; Park, H; Park, JW; Park, SJ; Seo, YS; Suh, SJ; Yim, HJ	1
Park, JG; Park, SY	1
Gao, Y; Han, T; Lian, J; Liu, F; Lyu, H; Wang, F; Xiang, H	1
Ao, Y; Chen, S; Chong, Y; Gao, Z; Huang, M; Jie, Y; Li, X; Lin, G; Shi, H; Wu, Y; Yang, F; Zhang, M	1
Cai, B; Chen, J; Liao, Y; Lu, X; Su, Z; Tao, C; Wang, L; Ying, B; Zhang, Q	1
Kittitrakul, C; Leowattana, W; Nontprasert, A; Phumratanaprapin, W; Poovorawan, K; Sriboonvorakul, N; Tangkijvanich, P; Thu, AM; Wilairatana, P	1
Bair, MJ; Chang, CW; Chen, CJ; Chen, MJ; Chu, CH; Hu, KC; Lee, KH; Lin, CC; Lin, SC; Liou, TC; Liu, CY; Shih, SC; Wang, HY; Wang, TE	1
Cao, Y; Dai, CY; Hou, W; Jiang, B; Li, XM; Lu, W; Su, R; Xu, J	1
Liu, Y; Qiu, P; Wang, GL; Wen, JB; Wen, P; Xiao, XZ; Xu, LF; Zhou, SF	1
Song, J; Sun, M; Tan, G; Wang, J; Wu, X	1
Chan, SH; Chang, TT; Cheng, PN; Huang, W; Lin, YJ; Su, IJ; Tsai, HW; Wu, HC; Wu, IC; Yen, CJ	1
Cheng, J; Liu, S; Wang, Q; Wang, X; Xing, H; Yang, S	1
Casarin, P; Castelnovo, L; Dal Maso, L; Gattei, V; Mauro, E; Mazzaro, C; Monti, G; Pozzato, G; Urraro, T; Zignego, AL	1
Chen, FY; Cheng, Z; Huang, HH; Shi, KQ; Zhang, MY; Zheng, JN; Zheng, MH; Zhu, GQ; Zou, ZL	1
Defresne, F; Sokal, E	1
Gao, Y; Ke, W; Liu, L; Yang, Y; Yao, Z; Ye, X; Zhang, C; Zhou, S	1
Hiraoka, A; Kumada, T; Tada, T; Tanaka, J; Toyoda, H; Tsuji, K	1
Ahn, SH; Choe, WH; Kim, JH; Kim, KH; Ko, SY; Kwon, SY	1
Bao, R; Bao, S; Chen, R; Guo, Q; Liu, K; Liu, Y; Wang, H; Xiang, X; Xie, J; Xie, Q	1
Akyildiz, M; Balci, D; Cinar, K; Dayangac, M; Gungor, G; Hazinedaroglu, S; Idilman, R; Kalkan, C; Keskin, O; Tokat, Y; Yilmaz, TU	1
Akriviadis, E; Antoniadis, N; Cholongitas, E; Fouzas, I; Giakoustidis, D; Giouleme, O; Goulis, I; Imvrios, G; Papanikolaou, V; Vasiliadis, T	1
Jia, J; Kong, Y; Wei, W; Wu, X; You, H; Zhou, J	1
Chen, Y; Cheng, KL; Duan, XW; Duan, ZP; Li, Y; Qiu, Q; Wang, L; Xu, MM; Yang, LK	1
Ahn, SH; Cho, EY; Hwang, SG; Jeong, SH; Jung, YK; Kim, HS; Kim, IH; Kim, JH; Kim, JW; Lee, JI; Lee, JM; Lee, JW; Lee, SH; Park, SJ; Seo, YS; Suh, SJ; Yim, HJ	1
Cho, YK; Choi, KY; Jeon, WK; Jung, YS; Kim, BI; Kim, HJ; Park, DI; Park, JH; Park, SK; Sohn, CI; Yang, HJ	1
Asano, M; Dohi, T; Enomoto, N; Gatanaga, H; Honda, M; Inoue, T; Kaneko, S; Kawamura, YI; Matsumoto, A; Mizokami, M; Murata, K; Nishida, N; Oka, S; Sakamoto, M; Shirasaki, T; Shuno, Y; Sugiyama, M; Tanaka, E; Yano, H	1
Hu, J; Ji, D; Li, X; Liao, H; Liu, Y; Wu, J; Xin, S; Xu, D; You, S; Zhang, XX; Zhao, J	1
Babudieri, S; Garrucciu, G; Madeddu, G; Maida, I; Melis, M; Mura, MS; Muredda, AA; Ortu, S	1
Aldern, KA; Beadle, JR; Broker, TR; Buckheit, RW; Chow, LT; Harden, EA; Hartman, T; Hostetler, KY; Keith, KA; Prichard, MN; Valiaeva, N; Yang, G; Yu, JH	1
Dixit, VK; Jain, AK; Nath, G; Singh, N; Srivastava, M	1
Hong, LJ; Wei, L; Ying, H; Zhang, J	1
Lim, YS	1
Chen, FY; Cheng, Z; Huang, HH; Shi, KQ; Van Poucke, S; Zhang, MY; Zheng, JN; Zheng, MH; Zhu, GQ	1
Capobianchi, MR; D'Offizi, G; Menzo, S; Piselli, P; Solmone, M; Vincenti, D	1
Arnold, E; Balzarini, J; Boehmer, PE; Das, K; Ford, A; Götte, M; Liekens, S; Maguire, AR; Maguire, NM; Menni, M; van Berckelaer, L	1
He, L; Jiang, Y; Liu, X; Wang, X; Yang, Z; Zhang, S; Zhao, Y	1
Hu, C; Huang, H; Li, Y; Liu, J; Yang, D; Yuan, G; Zhang, YY; Zhou, F; Zhou, Y	1
Aggeletopoulou, I; Anastassiou, ED; Assimakopoulos, S; Gogos, C; Kalafateli, M; Labropoulou-Karatza, C; Mandellou, M; Taprantzi, D; Thomopoulos, K; Triantos, C; Tselekouni, P; Tsiaoussis, G; Vourli, G	1
Guo, H; Jiao, J; Liu, Z; Qi, W; Wang, J; Wang, X; Xu, Y; Yu, F; Zhao, P; Zhou, C	1
Chang, S; Chen, B; Qiu, L; Shen, F; Sun, Y; Wu, K; Yu, L	1
Han, Z; Huang, M; Liu, J; Shi, H; Xia, J; Xue, J; Zhang, S; Zhu, Z	1
Lai, CL; Mak, LY; Seto, WK; Yuen, MF	1
Ahn, SH; Hur, SS; Kang, HS; Kim, DH; Kim, KH; Kwon, SY; Lee, AR; Lee, JH; Park, ES; Park, S; Park, YK; Sim, S	1
Banerjee, NS; Beadle, JR; Chow, LT; Hostetler, KY; Wang, HK	1
Chien, RN; Chu, HC; Chuang, WL; Hsu, CW; Huang, YH; Kao, JH; Lee, CM; Liaw, YF; Peng, CY; Su, WW	1
Chen, R; Cheng, Y; Li, Q; Li, X; Liao, H; Liu, L; Liu, Y; Shao, J; Su, H; Xu, D; Zhao, L; Zhao, Y; Zhou, Y	1
Chen, D; Guo, X; Li, Q; Liu, K; Ouyang, Y; Wang, Y; Wei, F; Wu, J; Zhang, Y	1
Lin, CL	1
Lin, Y; Modica, JA; Mrksich, M	1
Chen, YM; Deng, H; Gao, ZL; Lin, CS; Mei, YY; Peng, L; Xie, C; Xie, DY; Xu, WX; Zhang, Q; Zhao, ZX; Zhu, X	1
Caviglia, GP; Ngatchou, D; Olivero, A; Saracco, GM; Smedile, A	1
Balzarini, J; Ford, A; Maguire, AR; Maguire, NM	1
DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P	1
Hashimoto, S; Koike, T; Maoka, T; Okamoto, N; Watanabe, K; Yamamoto, R	1
Kan, QC; Li, ZQ; Yan, JY; Yu, ZJ	1
Dong, J; Huang, Y; Li, X; Wang, Y; Yu, F; Yu, Z	1
De Jonghe, S; Groaz, E; Herdewijn, P; Luo, M; Schols, D	1
Ahn, SH; Cho, YK; Choi, W; Han, KH; Hong, GY; Jang, JY; Jin, SY; Jung, YK; Kim, DJ; Kim, HS; Kim, JH; Kim, KH; Kim, MY; Kim, W; Kim, YJ; Kweon, YO; Lee, BS; Lee, JW; Lee, KS; Lee, WS; Lim, YS; Park, NH; Park, SJ; Sohn, JH; Um, SH; Yang, JM; Yim, HJ; Yoon, SK	1
Chen, EQ; Deng, R; Liao, J; Tang, H; Tao, CM; Wang, J; Wang, ML; Zhou, TY	1
Fan, YC; Qian, Y; Wang, JW; Wang, K; Wu, CS; Zhang, J; Zhao, Q	1
Li, T; Lin, C; Qu, Y; Wang, L; Wang, Y; Yang, B	1
Chang, Y; Cho, EJ; Cho, H; Cho, YY; Kim, YJ; Lee, JH; Nam, JY; Yoon, JH; Yu, SJ	1
Akita, T; Kumada, T; Kurisu, A; Miyake, N; Ohisa, M; Tada, T; Tanaka, J; Toyoda, H; Yasuda, S	1
Ji, J; Jia, Y; Shen, Y; Xun, P; Zhou, J	1
Kimura, A; Mizokami, M; Murata, K; Noguchi, M; Sugiyama, M; Suizu, F; Tsukuda, S; Watashi, K	1
Cai, S; Liao, W; Liu, L; Yin, S; Zheng, Z; Zhu, H	1
Cai, H; Duan, X; Fu, D; Gao, X; Hu, Y; Kang, K; Liu, M; Yi, W; Zhou, M	1
Babudieri, S; Bagella, P; Bandiera, F; Calvisi, DF; Fiore, V; Garrucciu, G; Madeddu, G; Mannu, F; Melis, M; Muredda, AA; Ortu, S; Zaru, S	1
Ahn, SH; Cho, YK; Han, KH; Hong, GY; Jang, JY; Jung, YK; Kim, DJ; Kim, HS; Kim, JH; Kim, MY; Kim, W; Kim, YJ; Kweon, YO; Lee, BS; Lee, JW; Lee, KS; Lee, WS; Lim, YS; Park, SJ; Sohn, JH; Um, SH; Yang, JM; Yim, HJ; Yoon, SK	1
Ahn, SH; Bae, SH; Heo, J; Jang, JY; Kim, CW; Kim, DJ; Kim, IH; Park, JY; Tak, WY; Woo, HY	1
Chen, R; Cheng, F; Duan, C; Huang, B; Li, X; Liu, Y; Luo, D; Si, L; Wang, J; Xu, D	1
Jang, BK	1
Ahn, SH; Cho, YK; Han, KH; Hong, GY; Jang, JY; Jung, YK; Kim, DJ; Kim, HS; Kim, JH; Kim, KH; Kim, MY; Kim, W; Kim, YJ; Kweon, YO; Lee, BS; Lee, JW; Lee, KS; Lee, WS; Lim, YS; Park, SJ; Sohn, JH; Song, DS; Um, SH; Yang, JM; Yim, HJ; Yoon, SK	1
Enomoto, M; Kawada, N; Nishiguchi, S; Tamori, A; Yoshida, K	1
Chen, R; Li, J; Li, L; Li, X; Liu, LM; Liu, Y; Shao, J; Xu, D; Zhao, L; Zhou, Y	1
Tseng, TC	1
Chen, R; Li, L; Li, X; Li, Y; Liao, H; Liu, W; Liu, Y; Si, L; Wang, J; Xu, D; Yao, Z; Zhao, J	1
Choi, YS; Han, JH; Hwang, JG; Kim, YK; Kwon, SK; Park, MK	1
Park, JY; Song, JE	1
Ahn, SH; Jang, JY; Jin, SY; Jung, YK; Kim, DJ; Kim, KH; Kim, W; Park, ES; Sohn, JH; Um, SH; Yim, HJ	1
Ahn, SH; Jung, CY; Kim, BS; Kim, HW; Kim, SU; Lee, HW; Lee, JI	1

Reviews

140 review(s) available for organophosphonates and guanine

Article	Year
Broad-spectrum anti-DNA virus and anti-retrovirus activity of phosphonylmethoxyalkylpurines and -pyrimidines. Biochemical pharmacology, 1991, Aug-08, Volume: 42, Issue:5 Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; DNA, Viral; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae; Virus Replication	1991
Antivirals for the treatment of herpesvirus infections. The Journal of antimicrobial chemotherapy, 1993, Volume: 32 Suppl A Topics: Acyclovir; Antiviral Agents; Belgium; Bromodeoxyuridine; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds	1993
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options. The Journal of hospital infection, 1996, Volume: 33, Issue:4 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine	1996
New therapeutic approaches to the alphaherpesvirus infections. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2 Topics: 2-Aminopurine; Acyclovir; Alphaherpesvirinae; Antibodies, Monoclonal; Arabinofuranosyluracil; Cidofovir; Cytosine; Famciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine	1997
Management of CMV retinitis in HIV infected patients. Genitourinary medicine, 1997, Volume: 73, Issue:3 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Prodrugs; Prospective Studies; Recurrence	1997
Antiviral agents for non-human immunodeficiency virus infections. Mayo Clinic proceedings, 1999, Volume: 74, Issue:12 Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir	1999
Therapeutic developments in cytomegalovirus retinitis. Expert opinion on investigational drugs, 2000, Volume: 9, Issue:2 Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drugs, Investigational; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valganciclovir	2000
Nucleoside analogues for chronic hepatitis B. European journal of gastroenterology & hepatology, 2001, Volume: 13, Issue:12 Topics: 2-Aminopurine; Adenine; Antiviral Agents; Famciclovir; Ganciclovir; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors	2001
Recent developments in herpesvirus therapy. Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:1 Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine	2001
[New management strategies for hepatitis B]. Gastroenterologie clinique et biologique, 2002, Volume: 26, Issue:2 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Lamivudine; Organophosphonates	2002
Prevention of recurrent hepatitis B post-liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2002, Volume: 8, Issue:10 Suppl 1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Organophosphonates; Postoperative Complications; Reverse Transcriptase Inhibitors; Secondary Prevention; Viral Hepatitis Vaccines	2002
Prevention of and treatment for hepatitis B virus infection after liver transplantation in the nucleoside analogues era. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2003, Volume: 3, Issue:3 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Postoperative Complications; Recurrence; Time Factors; Transplantation Immunology	2003
[Antiviral therapy for chronic viral hepatitis B and C]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferon-beta; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome	2003
Doctor to patient transmission of hepatitis B virus: implications of HBV DNA levels and potential new solutions. Antiviral research, 2003, Volume: 60, Issue:2 Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Infectious Disease Transmission, Professional-to-Patient; Interferon-alpha; Lamivudine; Organophosphonates; Organophosphorus Compounds; Physicians; Risk Factors; Risk Management; Tenofovir; Viral Load	2003
Treatment of HBeAg negative chronic hepatitis B with new drugs (adefovir and others). Journal of hepatology, 2003, Volume: 39 Suppl 1 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates	2003
Editorial comment: HIV and HBV coinfection--a coming-of-age in treatment strategies. The AIDS reader, 2004, Volume: 14, Issue:3 Topics: Adenine; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Tenofovir	2004
[New approaches in the treatment of hepatitis B]. Deutsche medizinische Wochenschrift (1946), 2004, May-21, Volume: 129, Issue:21 Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contraindications; Deoxycytidine; Emtricitabine; Famciclovir; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Organophosphorus Compounds; Polyethylene Glycols; Prodrugs; Prognosis; Recombinant Proteins; Tenofovir; Zalcitabine	2004
Molecular virology of hepatitis B virus. Seminars in liver disease, 2004, Volume: 24 Suppl 1 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Transcription, Genetic; Viral Proteins; Virus Replication	2004
New treatment of chronic hepatitis B. Seminars in liver disease, 2004, Volume: 24 Suppl 1 Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2004
Drugs in development for hepatitis B. Drugs, 2005, Volume: 65, Issue:11 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Interferon alpha-2; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir	2005
[Treatment of chronic hepatitis B]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:2 Pt 2 Topics: Adenine; Administration, Oral; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Drug Tolerance; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Lamivudine; Liver; Mutation; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Time Factors; Virus Replication	2006
[Liver transplantation for complications of hepatitis B]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:2 Pt 2 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunoglobulins; Lamivudine; Liver Cirrhosis; Liver Transplantation; Mutation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; Tenofovir; Time Factors; Vaccination; Viral Load; Virus Replication	2006
Medical therapy of patients affected by HBeAg-negative chronic hepatitis B. Minerva gastroenterologica e dietologica, 2006, Volume: 52, Issue:1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins	2006
Personal view: the management of chronic hepatitis B infection. Alimentary pharmacology & therapeutics, 2006, Apr-01, Volume: 23, Issue:7 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates; Tenofovir	2006
Prevention and treatment of recurrent Hepatitis B after liver transplantation: the current role of nucleoside and nucleotide analogues. Annals of clinical microbiology and antimicrobials, 2006, Apr-06, Volume: 5 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Nucleotides; Organophosphonates; Recurrence; Tenofovir	2006
Hepatitis B: the pathway to recovery through treatment. Gastroenterology clinics of North America, 2006, Volume: 35, Issue:2 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis C, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors	2006
New developments in the treatment of chronic hepatitis B. Expert opinion on biological therapy, 2006, Volume: 6, Issue:9 Topics: Adenine; Animals; Antiviral Agents; Clinical Trials as Topic; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Organophosphonates; Patient Selection; Polyethylene Glycols; Recombinant Proteins	2006
Antiretroviral therapy for hepatitis B virus-HIV-coinfected patients: promises and pitfalls. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Oct-01, Volume: 43, Issue:7 Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Combinations; Emtricitabine; Guanine; Hepatitis B; Hepatitis B virus; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Preventive Medicine; Tenofovir	2006
Drug evaluation: LB-80380--a novel phosphonate nucleoside for the potential treatment of HBV infection. Current opinion in molecular therapeutics, 2006, Volume: 8, Issue:4 Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Guanine; Hepatitis B; Humans; Organophosphonates	2006
[Therapy of hepatitis B virus infection]. Praxis, 2006, Sep-06, Volume: 95, Issue:36 Topics: Adenine; Antiviral Agents; Drug Antagonism; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Forecasting; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Organophosphonates; Polyethylene Glycols; Prognosis; Recombinant Proteins; Reverse Transcriptase Inhibitors; Time Factors	2006
[Treating chronic lamivudine-resistant hepatitis B in HIV co-infected patients]. Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:10 Pt 2 Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2006
Cross-study analysis of the relative efficacies of oral antiviral therapies for chronic hepatitis B infection in nucleoside-naive patients. Clinical drug investigation, 2007, Volume: 27, Issue:1 Topics: Adenine; Administration, Oral; Algorithms; Antiviral Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Randomized Controlled Trials as Topic; Treatment Outcome	2007
Improving outcomes for patients with chronic hepatitis B. Current gastroenterology reports, 2007, Volume: 9, Issue:1 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome; Viral Load	2007
[Drugs for hepatitis B and C infection]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Feb-28, Volume: 65 Suppl 2 Pt. 1 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Lamivudine; Mutation; Oligopeptides; Organophosphonates; Proline; Ribavirin; Serine Proteinase Inhibitors	2007
[Mechanisms of drug resistance in hepatitis viruses B and C]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Feb-28, Volume: 65 Suppl 2 Pt. 1 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Gene Products, pol; Guanine; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Interferons; Lamivudine; Mutation; Organophosphonates; Ribavirin; Viral Nonstructural Proteins	2007
Treatment paradigms on hepatitis B e antigen-negative chronic hepatitis B patients. Expert opinion on investigational drugs, 2007, Volume: 16, Issue:6 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine	2007
Drug resistance in antiviral treatment for infections with hepatitis B and C viruses. Journal of gastroenterology, 2007, Volume: 42, Issue:5 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Lamivudine; Organophosphonates	2007
Treatment of chronic hepatitis B in HIV-infected patients in 2007. Journal of HIV therapy, 2007, Volume: 12, Issue:1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2007
Chronic hepatitis B with advanced fibrosis or cirrhosis: impact of antiviral therapy. Reviews in gastroenterological disorders, 2007,Spring, Volume: 7, Issue:2 Topics: Adenine; Antiviral Agents; Disease Progression; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Organophosphonates	2007
[Indications for antiviral therapy for chronic hepatitis B]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:10 Topics: Adenine; Antiviral Agents; Biomarkers; Carrier State; Consensus Development Conferences as Topic; DNA, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Japan; Lamivudine; Organophosphonates; Societies, Medical	2007
[Therapy for chronic hepatitis B: relationship between HBV genotype and efficacy or resistance of anti-viral therapy]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:10 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates	2007
[Attention-getting sexually transmitted diseases: Hepatitis B]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Nov-10, Volume: 96, Issue:11 Topics: Adenine; Adenosine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Genotype; Guanine; Guanosine; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Sexually Transmitted Diseases, Viral	2007
Review article: Success and failure of nucleoside and nucleotide analogues in chronic hepatitis B. Alimentary pharmacology & therapeutics, 2007, Volume: 26 Suppl 2 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Factors; Virus Replication	2007
[Pharmacological agents for the treatment of chronic hepatitis B]. Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:3 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome	2008
Evaluating anti-viral drug selection and treatment duration in HBeAg-negative chronic hepatitis B: a cost-effectiveness analysis. Alimentary pharmacology & therapeutics, 2008, Volume: 27, Issue:12 Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Epidemiologic Methods; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates	2008
Review article: current antiviral therapy of chronic hepatitis B. Alimentary pharmacology & therapeutics, 2008, Volume: 28, Issue:2 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication	2008
[Treatment recommendations of chronic hepatitis B. Did the world escape us?]. Przeglad epidemiologiczny, 2008, Volume: 62, Issue:1 Topics: Adenine; Antiviral Agents; Disease Management; Drug Therapy, Combination; Guanine; Health Planning Guidelines; Health Services Accessibility; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; National Health Programs; Organophosphonates; Poland; Polyethylene Glycols; Randomized Controlled Trials as Topic; Recombinant Proteins; Treatment Outcome	2008
Treatment of chronic hepatitis B infection: an update of Swedish recommendations. Scandinavian journal of infectious diseases, 2008, Volume: 40, Issue:6-7 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Immunocompromised Host; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Transplantation; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Sweden; Tenofovir	2008
[Management of chronic hepatitis B in treatment-naive patients]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 51, Issue:6 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Korea; Lamivudine; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins	2008
[Management of antiviral-resistant chronic hepatitis B virus infection]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 51, Issue:6 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome	2008
LB80380: a promising new drug for the treatment of chronic hepatitis B. Expert opinion on investigational drugs, 2008, Volume: 17, Issue:10 Topics: Adenine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunologic Factors; Organophosphonates; Practice Guidelines as Topic	2008
Hepatitis B and liver transplantation: 2008 update. Reviews in medical virology, 2009, Volume: 19, Issue:1 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B Vaccines; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2009
A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: 2008 update. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:12 Topics: Adenine; Antiviral Agents; Case Management; DNA, Viral; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome; United States	2008
[Acyclic nucleoside phosphonates as potential antineoplastic agents]. Casopis lekaru ceskych, 2008, Volume: 147, Issue:9 Topics: Adenine; Alanine; Animals; Antineoplastic Agents; Cell Line, Tumor; Guanine; Humans; Lymphoma, Non-Hodgkin; Nucleosides; Organophosphonates; Organophosphorus Compounds; Purines	2008
[Interferon in hepatitis B]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome	2008
[Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication	2008
[Entecavir]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; Humans; Lamivudine; Liver Cirrhosis; Liver Transplantation; Multicenter Studies as Topic; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Virus Replication	2008
[Resistance in hepatitis B virus]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Gene Products, pol; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Models, Molecular; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Virus Replication	2008
[Clinical management of patients with chronic hepatitis B virus infection]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Antiviral Agents; Biopsy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver; Liver Transplantation; Male; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication	2008
[Hepatitis B in patients with HIV infection]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication	2008
Role of combination therapy in chronic hepatitis B. Current gastroenterology reports, 2009, Volume: 11, Issue:1 Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates; Salvage Therapy; Treatment Outcome	2009
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success. Best practice & research. Clinical gastroenterology, 2008, Volume: 22, Issue:6 Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Treatment Outcome; Virus Replication	2008
Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues. Best practice & research. Clinical gastroenterology, 2008, Volume: 22, Issue:6 Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2008
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues. Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29 Suppl 1 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Replication	2009
Post-liver transplant hepatitis B prophylaxis: the role of oral nucleos(t)ide analogues. Current opinion in organ transplantation, 2009, Volume: 14, Issue:3 Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Guanine; Hepatitis B; Humans; Immunoglobulins; Injections, Intramuscular; Lamivudine; Liver Transplantation; Nucleosides; Nucleotides; Organophosphonates; Secondary Prevention; Tenofovir; Treatment Outcome	2009
[Chronic hepatitis B: current therapy]. Bulletin de l'Academie nationale de medecine, 2008, Volume: 192, Issue:8 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Guanine; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Humans; Immunotherapy, Active; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome	2008
Avoiding and managing lamivudine resistance in chronic hepatitis B: current approaches and potential strategies including pegylated interferon. Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:5 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir	2010
Effect of newer oral antiviral agents on future therapy of chronic hepatitis B. Antiviral therapy, 2010, Volume: 15, Issue:1 Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2010
Current therapeutic strategies for recurrent hepatitis B virus infection after liver transplantation. World journal of gastroenterology, 2010, May-28, Volume: 16, Issue:20 Topics: Adenine; Antiviral Agents; Asia; Guanine; Hepatitis B; Hepatitis B virus; Humans; Interferons; Lamivudine; Liver Transplantation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; Tenofovir	2010
On-treatment monitoring of chronic hepatitis B virus infection: an Asian-Pacific perspective. Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:5 Topics: Adenine; Antiviral Agents; Asia; Biomarkers; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication	2010
Tenofovir and entecavir are the most effective antiviral agents for chronic hepatitis B: a systematic review and Bayesian meta-analyses. Gastroenterology, 2010, Volume: 139, Issue:4 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Tenofovir	2010
Mixed treatment comparison meta-analysis evaluating the relative efficacy of nucleos(t)ides for treatment of nucleos(t)ide-naive patients with chronic hepatitis B. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2010, Volume: 13, Issue:8 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load	2010
The search for new therapies for human cytomegalovirus infections. Virus research, 2011, Volume: 157, Issue:2 Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Valganciclovir; Virus Replication	2011
Review article: chronic hepatitis B - anti-viral or immunomodulatory therapy? Alimentary pharmacology & therapeutics, 2011, Volume: 33, Issue:5 Topics: Adenine; Antiviral Agents; Decision Making; Guanine; Hepatitis B, Chronic; Humans; Immunomodulation; Interferon alpha-2; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Randomized Controlled Trials as Topic; Recombinant Proteins; Tenofovir; Treatment Outcome	2011
Chronic hepatitis B: peginterferon or nucleos(t)ide analogues? Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome	2011
Treatment of HBeAg-positive chronic hepatitis B with nucleos(t)ide analogues. Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2011
Hepatitis B virus resistance to antiviral drugs: where are we going? Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1 Topics: Adenine; Antiviral Agents; Capsid; Clinical Protocols; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Internalization; Virus Replication	2011
The impact of human immunodeficiency virus on viral hepatitis. Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1 Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis C; Hepatitis Viruses; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2011
[Treatment of patients with lamivudine-resistant chronic hepatitis B]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:2 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates	2011
Comparison of the 48-week efficacy between entecavir and adefovir in HBeAg-positive nucleos(t)ide-naïve Asian patients with chronic hepatitis B: a meta-analysis. Virology journal, 2011, Feb-22, Volume: 8 Topics: Adenine; Antiviral Agents; Asia; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Organophosphonates; Randomized Controlled Trials as Topic	2011
Novel nephrotoxins. Advances in chronic kidney disease, 2011, Volume: 18, Issue:3 Topics: Adenine; Alcohols; Angiogenesis Inhibitors; Anticonvulsants; Antipsychotic Agents; Dasatinib; Diphosphonates; Glutamates; Guanine; HIV Protease Inhibitors; Humans; Indoles; Kidney Diseases; Organophosphonates; Oxalates; Pamidronate; Pemetrexed; Phenindione; Plants, Toxic; Proton Pump Inhibitors; Pyrimidines; Pyrroles; Selective Serotonin Reuptake Inhibitors; Sunitinib; Tenofovir; Thiazoles; Triazines	2011
[Interferon-based versus direct antiviral therapy in patients with chronic hepatitis B]. Orvosi hetilap, 2011, May-29, Volume: 152, Issue:22 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2011
[Progress and perspectives in treatment of chronic hepatitis B]. Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:4 Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates	2011
Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding. Antiviral therapy, 2011, Volume: 16, Issue:5 Topics: Adenine; Antiviral Agents; Breast Feeding; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2011
Lamivudine plus adefovir combination therapy versus entecavir monotherapy for lamivudine-resistant chronic hepatitis B: a systematic review and meta-analysis. Virology journal, 2011, Aug-08, Volume: 8 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Salvage Therapy; Time Factors; Treatment Outcome; Viral Load	2011
Antiviral drugs for viruses other than human immunodeficiency virus. Mayo Clinic proceedings, 2011, Volume: 86, Issue:10 Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir	2011
[The past, present and future treatment for chronic hepatitis B]. Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 4 Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates; Practice Guidelines as Topic	2011
Management of severe acute to fulminant hepatitis B: to treat or not to treat or when to treat? Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:4 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Interferons; Lamivudine; Liver Failure, Acute; Organophosphonates; Tenofovir	2012
[Pharmacological treatment of acute hepatitis B]. Medicina clinica, 2012, May-19, Volume: 138, Issue:14 Topics: Acute Disease; Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Spain; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2012
Quantification of serum hepatitis B surface antigen: is it useful for the management of chronic hepatitis B? Gut, 2012, Volume: 61, Issue:5 Topics: Adenine; Antiviral Agents; Biomarkers; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Viral Load	2012
Emerging pipeline drugs for hepatitis B infection. Expert opinion on emerging drugs, 2011, Volume: 16, Issue:4 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Design; Drugs, Investigational; Guanine; Hepatitis B Antigens; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir; Treatment Outcome; Virus Replication	2011
Meta-analysis: oral anti-viral agents in adults with decompensated hepatitis B virus cirrhosis. Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:6 Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load	2012
New advances in chronic hepatitis B. Current opinion in gastroenterology, 2012, Volume: 28, Issue:3 Topics: Adenine; Antiviral Agents; Coinfection; Disease Progression; Drug Resistance, Viral; Female; Guanine; Guidelines as Topic; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis D; HIV Infections; Humans; Interferons; Liver Cirrhosis; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Tenofovir	2012
New perspectives in the therapy of chronic hepatitis B. Gut, 2012, Volume: 61 Suppl 1 Topics: Adenine; Antiviral Agents; Drug Monitoring; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Interleukins; Organophosphonates; Polymorphism, Genetic; Prognosis; Tenofovir	2012
First-line treatment of chronic hepatitis B with entecavir or tenofovir in 'real-life' settings: from clinical trials to clinical practice. Journal of viral hepatitis, 2012, Volume: 19, Issue:6 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Nucleotides; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load	2012
High genetic barrier nucleos(t)ide analogue(s) for prophylaxis from hepatitis B virus recurrence after liver transplantation: a systematic review. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2013, Volume: 13, Issue:2 Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Liver Failure; Liver Transplantation; Nucleotides; Organophosphonates; Recurrence; Tenofovir; Time Factors; Treatment Outcome	2013
Long-term therapy with nucleoside/nucleotide analogues for chronic hepatitis B in Asian patients. Antiviral therapy, 2013, Volume: 18, Issue:7 Topics: Adenine; Antiviral Agents; Asian People; Carcinoma, Hepatocellular; Disease Progression; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Organophosphonates; Tenofovir; Treatment Outcome	2013
Considerations for the long-term treatment of chronic hepatitis B with nucleos(t)ide analogs. Expert review of gastroenterology & hepatology, 2012, Volume: 6, Issue:6 Topics: Adenine; Age Factors; Antiviral Agents; Comorbidity; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Life Style; Organophosphonates; Severity of Illness Index; Telbivudine; Tenofovir; Thymidine; Time Factors	2012
Diagnostic and therapeutic progress of multi-drug resistance with anti-HBV nucleos(t)ide analogues. World journal of gastroenterology, 2012, Dec-28, Volume: 18, Issue:48 Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Transplantation; Mutation; Nucleosides; Nucleotides; Organophosphonates; Prognosis; Tenofovir; Viral Load	2012
Cost effectiveness of first-line oral antiviral therapies for chronic hepatitis B : a systematic review. PharmacoEconomics, 2013, Volume: 31, Issue:1 Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Guanine; Health Care Costs; Hepatitis B, Chronic; Humans; Models, Economic; Organophosphonates; Reproducibility of Results; Tenofovir	2013
Letter: First-line monotherapies for chronic hepatitis B - indirect comparison between entecavir and tenofovir. Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:5 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2013
Update in the management of chronic hepatitis B. Current opinion in gastroenterology, 2013, Volume: 29, Issue:3 Topics: Adenine; Antiviral Agents; Drug Monitoring; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon Type I; Organophosphonates; Practice Guidelines as Topic; Tenofovir	2013
Meta-analysis: the impact of oral anti-viral agents on the incidence of hepatocellular carcinoma in chronic hepatitis B. Alimentary pharmacology & therapeutics, 2013, Volume: 38, Issue:2 Topics: Adenine; Administration, Oral; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2013
Viral hepatitis and HIV: update and management. Antiviral therapy, 2013, Volume: 18, Issue:3 Pt B Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Coinfection; Drug Therapy, Combination; Guanine; Hepatitis C; HIV Infections; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Protease Inhibitors; Recombinant Proteins; Ribavirin; Tenofovir	2013
[Interdisciplinary aspects of and new drugs for chronic hepatitis B]. Orvosi hetilap, 2013, Jul-21, Volume: 154, Issue:29 Topics: Adenine; Antiviral Agents; Comorbidity; Drug Interactions; Drug Therapy, Combination; Female; Gastroenterology; Guanine; Hematology; Hepatitis B, Chronic; Humans; Hungary; Infant, Newborn; Infant, Newborn, Diseases; Infectious Disease Transmission, Vertical; Interdisciplinary Communication; Interferons; Lamivudine; Medical Oncology; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Rheumatology; Tenofovir	2013
Long-term results of treatment with nucleoside and nucleotide analogues (entecavir and tenofovir) for chronic hepatitis B. Clinics in liver disease, 2013, Volume: 17, Issue:3 Topics: Adenine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir; Treatment Outcome; Virus Replication	2013
[Reactivation of chronic hepatitis B]. Vnitrni lekarstvi, 2013, Volume: 59, Issue:7 Topics: Adenine; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antiviral Agents; Biomarkers; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Immunosuppressive Agents; Inflammation; Lamivudine; Organophosphonates; Rituximab; Tenofovir; Virus Activation	2013
Efficacy of lamivudine combined with adefovir dipivoxil versus entecavir monotherapy in patients with hepatitis B-associated decompensated cirrhosis: A meta-analysis. Journal of clinical pharmacology, 2014, Volume: 54, Issue:2 Topics: Adenine; Alanine Transaminase; Antiviral Agents; Creatinine; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Randomized Controlled Trials as Topic; Treatment Outcome	2014
Comparison of the efficacy of Lamivudine plus adefovir versus entecavir in the treatment of Lamivudine-resistant chronic hepatitis B: a systematic review and meta-analysis. Clinical therapeutics, 2013, Volume: 35, Issue:12 Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Treatment Outcome	2013
Review article: nucleos(t)ide analogues in patients with chronic hepatitis B virus infection and chronic kidney disease. Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Renal Insufficiency, Chronic; Telbivudine; Tenofovir; Thymidine	2014
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible? Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1 Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Telbivudine; Tenofovir; Thymidine	2014
HBeAg-positive chronic hepatitis B: why do i treat my patients with Nucleos(t)ide analogs? Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1 Topics: Adenine; Age Factors; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Precision Medicine; Recombinant Proteins; Sex Factors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2014
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues? Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1 Topics: Adenine; Age Factors; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Precision Medicine; Recombinant Proteins; Sex Factors; Tenofovir; Treatment Outcome	2014
Impact of HBV therapy on the incidence of hepatocellular carcinoma. Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Tenofovir	2014
New therapeutic perspectives in HBV: when to stop NAs. Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1 Topics: Adenine; Algorithms; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine	2014
Peginterferon alpha versus other antiviral regimes for Chinese HBeAg-positive chronic hepatitis B patients. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2013, Volume: 38, Issue:12 Topics: Adenine; Antiviral Agents; China; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols	2013
An update on hepatitis B, D, and E viruses. Topics in antiviral medicine, 2014, Volume: 21, Issue:5 Topics: Adenine; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Hepatitis D, Chronic; Hepatitis E; Humans; Interferon-alpha; Liver Cirrhosis; Liver Failure; Organophosphonates; Tenofovir; Treatment Outcome	2014
Managing hepatitis B to prevent liver cancer: recent advances. Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:4 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2014
Efficacy and resistance in de novo combination lamivudine and adefovir dipivoxil therapy versus entecavir monotherapy for the treatment-naive patients with chronic hepatitis B: a meta-analysis. Virology journal, 2014, Mar-28, Volume: 11 Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Treatment Outcome	2014
Advances in the treatment of hepatitis B virus/hepatitis C virus coinfection. Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:10 Topics: Adenine; Antiviral Agents; Coinfection; DNA, Viral; Drug Therapy, Combination; Guanine; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Humans; Organophosphonates; Ribavirin; RNA, Viral; Tenofovir; Virus Replication	2014
Management of chronic hepatitis B in children: an unresolved issue. Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:5 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Carrier State; Child; Databases, Bibliographic; Guanine; Hepatitis B, Chronic; Humans; Immune Tolerance; Incidence; Interferons; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Risk; Tenofovir	2014
Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments. World journal of gastroenterology, 2014, May-28, Volume: 20, Issue:20 Topics: Adenine; Antiviral Agents; Disease Management; DNA, Viral; Drug Delivery Systems; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B, Chronic; Humans; Interferons; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Tenofovir; Viral Load	2014
Comparison of efficacy and safety of tenofovir and entecavir in chronic hepatitis B virus infection: a systematic review and meta-analysis. PloS one, 2014, Volume: 9, Issue:6 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Safety; Tenofovir	2014
Management of patients with overt or resolved hepatitis B virus infection undergoing rituximab therapy. Expert opinion on biological therapy, 2014, Volume: 14, Issue:7 Topics: Adenine; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Carrier State; Disease Management; DNA, Viral; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Organophosphonates; Rituximab; Tenofovir; Virus Activation	2014
Molecular diagnosis and treatment of drug-resistant hepatitis B virus. World journal of gastroenterology, 2014, May-21, Volume: 20, Issue:19 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Molecular Diagnostic Techniques; Mutation; Nucleic Acid Hybridization; Organophosphonates; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Tenofovir; Treatment Outcome	2014
Entecavir plus adefovir combination therapy versus lamivudine add-on adefovir for lamivudine-resistant chronic hepatitis B: A meta-analysis. Journal of clinical pharmacology, 2014, Volume: 54, Issue:9 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Treatment Outcome	2014
Treatment of chronic hepatitis B in clinical practice with entecavir or tenofovir. World journal of gastroenterology, 2014, Jun-21, Volume: 20, Issue:23 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir; Treatment Outcome	2014
Prevention of hepatitis B virus reinfection in liver transplant recipients. Intervirology, 2014, Volume: 57, Issue:3-4 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Liver; Liver Cirrhosis; Liver Transplantation; Organophosphonates; Recurrence; Reverse Transcriptase Inhibitors; Tenofovir; Transplant Recipients; Virus Replication	2014
Optimal therapy of chronic hepatitis B: how do I treat HBeAg-positive patients? Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35 Suppl 1 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Long-Term Care; Organophosphonates; Tenofovir; Treatment Outcome	2015
Optimal therapy of chronic hepatitis B: how do I treat my HBeAg-negative patients? Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35 Suppl 1 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Long-Term Care; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome; Virus Replication	2015
Monotherapy for hepatitis B infection: a review of treatment options. Expert review of anti-infective therapy, 2015, Volume: 13, Issue:12 Topics: Adenine; Animals; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Neoplasms; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome	2015
Systematic review with network meta-analysis: Comparative efficacy of oral nucleos(t)ide analogues for the prevention of chemotherapy-induced hepatitis B virus reactivation. Oncotarget, 2016, May-24, Volume: 7, Issue:21 Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Controlled Clinical Trials as Topic; Guanine; Hepatitis B; Hepatitis B virus; Host-Pathogen Interactions; Humans; Lamivudine; Organophosphonates; Telbivudine; Thymidine; Virus Activation	2016
Chronic hepatitis B in children: Therapeutic challenges and perspectives. Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:2 Topics: Adenine; Alanine Transaminase; Antigens, Viral; Antiviral Agents; Child; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Tolerance; Interferon-alpha; Lamivudine; Molecular Targeted Therapy; Organophosphonates; Practice Guidelines as Topic; Seroconversion; Telbivudine; Tenofovir; Thymidine; Viral Envelope Proteins	2017
A Meta-Analysis of the Efficacy of Interferon Monotherapy or Combined with Different Nucleos(t)ide Analogues for Chronic Hepatitis B. International journal of environmental research and public health, 2016, 07-21, Volume: 13, Issue:5 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Odds Ratio; Organophosphonates; Treatment Outcome	2016
Management of Antiviral Resistance in Chronic Hepatitis B. Gut and liver, 2017, Mar-15, Volume: 11, Issue:2 Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Tenofovir	2017
Nucleos(t)ide analogues for preventing HBV reactivation in immunosuppressed patients with hematological malignancies: a network meta-analysis. Expert review of anti-infective therapy, 2017, Volume: 15, Issue:5 Topics: Adenine; Antiviral Agents; Controlled Clinical Trials as Topic; Guanine; Hematologic Neoplasms; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Lamivudine; Organophosphonates; Survival Analysis; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Activation	2017
Efficacy of Nucleot(s)ide Analogs Therapy in Patients with Unresectable HBV-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. Disease markers, 2017, Volume: 2017 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Organophosphonates; Retrospective Studies; Survival Analysis; Telbivudine; Tenofovir; Thymidine	2017
Pharmacokinetic evaluation of besifovir for the treatment of HBV infection. Expert opinion on drug metabolism & toxicology, 2018, Volume: 14, Issue:1 Topics: Administration, Oral; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Guanine; Half-Life; Hepatitis B, Chronic; Humans; Organophosphonates; Prodrugs	2018
Bayesian Network Meta-Analysis for Assessing Adverse Effects of Anti-hepatitis B Drugs. Clinical drug investigation, 2019, Volume: 39, Issue:9 Topics: Adenine; Antiviral Agents; Bayes Theorem; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Network Meta-Analysis; Organophosphonates; Prospective Studies; Telbivudine; Tenofovir	2019
Combination of Entecavir or Tenofovir with Pegylated Interferon-α for Long-Term Reduction in Hepatitis B Surface Antigen Levels: Simultaneous, Sequential, or Add-on Combination Therapy. International journal of molecular sciences, 2021, Feb-01, Volume: 22, Issue:3 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Randomized Controlled Trials as Topic; Reproducibility of Results; Tenofovir; Treatment Outcome; Viral Load	2021

Trials

59 trial(s) available for organophosphonates and guanine

Article	Year
A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B. Antiviral therapy, 2006, Volume: 11, Issue:8 Topics: Adult; Antiviral Agents; Dose-Response Relationship, Drug; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Molecular Structure; Organophosphonates	2006
Absence of a pharmacokinetic interaction between entecavir and adefovir. Journal of clinical pharmacology, 2007, Volume: 47, Issue:10 Topics: Adenine; Adolescent; Adult; Antiviral Agents; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Guanine; Humans; Male; Organophosphonates	2007
Cost effectiveness of entecavir versus lamivudine with adefovir salvage in HBeAg-positive chronic hepatitis B. PharmacoEconomics, 2007, Volume: 25, Issue:11 Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Cohort Studies; Cost-Benefit Analysis; Disease Progression; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Organophosphonates; Quality of Life; Salvage Therapy	2007
Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:1 Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Viral Load	2009
[A study on the treatment of chronic hepatitis B with YMDD mutation]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:3 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Young Adult	2009
Efficacy of entecavir in patients with chronic hepatitis B resistant to both lamivudine and adefovir or to lamivudine alone. Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:4 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Treatment Outcome	2009
Rescue monotherapy in lamivudine-resistant hepatitis B e antigen-positive chronic hepatitis B: adefovir versus entecavir. Antiviral therapy, 2009, Volume: 14, Issue:5 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy; Treatment Outcome; Young Adult	2009
Antiviral activity and safety of LB80380 in hepatitis B e antigen-positive chronic hepatitis B patients with lamivudine-resistant disease. Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:3 Topics: Adult; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Young Adult	2010
[Comparison of efficacy between adefovir dipivoxil and entecavir in patients with chronic hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2010, Volume: 18, Issue:1 Topics: Adenine; Administration, Oral; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Polymerase Chain Reaction; Prospective Studies; Treatment Outcome; Virus Replication	2010
Antiviral effect of entecavir in chronic hepatitis B: influence of prior exposure to nucleos(t)ide analogues. Journal of hepatology, 2010, Volume: 52, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Prospective Studies; Reverse Transcriptase Inhibitors; Virus Replication	2010
[Comparison of the efficacy of 48 week-Entecavir therapy with that of Adefovir therapy for chronic hepatitis B patients]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2010, Volume: 18, Issue:5 Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult	2010
Long-term therapy with tenofovir is effective for patients co-infected with human immunodeficiency virus and hepatitis B virus. Gastroenterology, 2010, Volume: 139, Issue:6 Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; Humans; Kaplan-Meier Estimate; Kidney; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Time Factors; Virus Replication	2010
Efficacy of adefovir add-on lamivudine rescue therapy compared with switching to entecavir monotherapy in patients with lamivudine-resistant chronic hepatitis B. Journal of medical virology, 2010, Volume: 82, Issue:11 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult	2010
Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease. Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:1 Topics: Adenine; Adolescent; Adult; Aged; Creatinine; Deoxycytidine; DNA, Viral; Drug Combinations; Emtricitabine; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load	2011
Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic hepatitis B patients receiving oral antiviral agents. Journal of medical virology, 2011, Volume: 83, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Blood; DNA, Circular; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Histocytochemistry; Humans; Liver; Male; Middle Aged; Organophosphonates; Placebos; Treatment Outcome; Viral Load	2011
Efficacy and safety of entecavir versus adefovir in chronic hepatitis B patients with hepatic decompensation: a randomized, open-label study. Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:1 Topics: Adenine; Antiviral Agents; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Failure; Male; Middle Aged; Organophosphonates; Survival Rate; Treatment Outcome	2011
[Safety and efficacy of Entecavir combined with Adefovir in patients with chronic hepatitis B who fail to respond to nucleoside analog treatment]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:6 Topics: Adenine; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Treatment Failure	2011
Simple scoring system predicting genotypic resistance during rescue therapy for Lamivudine-resistant chronic hepatitis B. Journal of clinical gastroenterology, 2012, Volume: 46, Issue:3 Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Predictive Value of Tests; Retrospective Studies; Survival Analysis; Treatment Outcome; Young Adult	2012
[Efficacy of two nucleoside analogs to treat resistant HBeAg-negative chronic hepatitis B]. Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2011, Volume: 25, Issue:4 Topics: Adenine; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult	2011
[Clinical antiviral effects of Peg-IFNa-2a in patients with chronic hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2011, Volume: 19, Issue:9 Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Treatment Outcome	2011
Treatment response and evolution of HBV resistance during lamivudine plus adefovir or entecavir therapy in patients with adefovir-resistant mutants. Antiviral therapy, 2012, Volume: 17, Issue:4 Topics: Adenine; Adult; Aged; Antiviral Agents; Base Sequence; Cloning, Molecular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates	2012
Randomized trial of entecavir plus adefovir in patients with lamivudine-resistant chronic hepatitis B who show suboptimal response to lamivudine plus adefovir. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6 Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult	2012
[Entecavir 1.0mg monotherapy or entecavir plus adefovir dipivoxil for patients with lamivudine-resistant chronic hepatitis B had suboptimal response to lamivudine plus adefovir dipivoxil]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2011, Volume: 19, Issue:11 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome	2011
Efficacy of entecavir with or without tenofovir disoproxil fumarate for nucleos(t)ide-naïve patients with chronic hepatitis B. Gastroenterology, 2012, Volume: 143, Issue:3 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Linear Models; Organophosphonates; Phosphorous Acids; Time Factors; Treatment Outcome; Viral Load	2012
Virologic responses to add-on adefovir dipivoxil treatment versus entecavir monotherapy in children with lamivudine-resistant chronic hepatitis B. Journal of pediatric gastroenterology and nutrition, 2012, Volume: 55, Issue:6 Topics: Adenine; Adolescent; Antiviral Agents; Child; Child, Preschool; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Treatment Outcome; Viral Load	2012
Rescue therapy for lamivudine-resistant chronic hepatitis B: adefovir monotherapy, adefovir plus lamivudine or entecavir combination therapy. Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:12 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Time Factors	2012
Clonal analysis of the quasispecies of antiviral-resistant HBV genomes in patients with entecavir resistance during rescue treatment and successful treatment of entecavir resistance with tenofovir. Antiviral therapy, 2013, Volume: 18, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genome, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Tenofovir; Treatment Outcome; Young Adult	2013
Pharmacokinetic comparison of the maleate and free base formulations of LB80380, a novel nucleotide analog, in healthy male volunteers. International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:9 Topics: Administration, Oral; Adult; Antiviral Agents; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, Liquid; Cross-Over Studies; Guanine; Hepatitis B, Chronic; Humans; Male; Maleates; Metabolic Clearance Rate; Middle Aged; Organophosphonates; Prodrugs; Republic of Korea; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult	2012
Comparison of the antiviral effects of entecavir and adefovir dipivoxil in chronic HBV infection: a randomized control trial. Acta gastro-enterologica Belgica, 2012, Volume: 75, Issue:3 Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; Bilirubin; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Virus Replication; Young Adult	2012
Adding adefovir vs. switching to entecavir for lamivudine-resistant chronic hepatitis B (ACE study): a 2-year follow-up randomized controlled trial. Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:2 Topics: Adenine; Adult; Analysis of Variance; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Immunoassay; Lamivudine; Male; Middle Aged; Oligonucleotides; Organophosphonates; Prospective Studies; Republic of Korea; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome	2013
Efficacy and safety of telbivudine plus adefovir dipivoxil combination therapy and entecavir monotherapy for HBeAg-positive chronic hepatitis B patients with resistance to adefovir dipivoxil. Journal of viral hepatitis, 2013, Volume: 20 Suppl 1 Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome	2013
Antiviral efficacies of currently available rescue therapies for multidrug-resistant chronic hepatitis B. Clinical and molecular hepatology, 2013, Volume: 19, Issue:1 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome	2013
Randomized trial of the virologic response during up to two years of entecavir-adefovir combination therapy in multiple-drug-refractory chronic hepatitis B virus patients. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome; Viral Load; Young Adult	2013
Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B. Gut, 2014, Volume: 63, Issue:6 Topics: Adult; Alanine Transaminase; Antibodies, Viral; Antiviral Agents; Asian People; Carnitine; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Intention to Treat Analysis; Male; Middle Aged; Mutation; Organophosphonates; Young Adult	2014
De novo combined lamivudine and adefovir dipivoxil therapy vs entecavir monotherapy for hepatitis B virus-related decompensated cirrhosis. World journal of gastroenterology, 2013, Oct-07, Volume: 19, Issue:37 Topics: Adenine; Adult; Alanine Transaminase; Analysis of Variance; Antiviral Agents; Biomarkers; Chi-Square Distribution; China; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Prospective Studies; Time Factors; Treatment Outcome	2013
Add-on peg-interferon leads to loss of HBsAg in patients with HBeAg-negative chronic hepatitis and HBV DNA fully suppressed by long-term nucleotide analogs. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, Volume: 58, Issue:4 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Prospective Studies; Recombinant Proteins	2013
[Therapeutic effect of antiviral regimens for chronic hepatitis B refractory to lamivudine plus adefovir]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2013, Volume: 33, Issue:12 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Mutation; Organophosphonates; Real-Time Polymerase Chain Reaction; Recombinant Proteins	2013
Entecavir 1mg versus combined lamivudine/adefovir dipivoxil in chronic HBV Egyptian patients resistant to LAM monotherapy, non-randomised controlled study. Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2014, Volume: 15, Issue:1 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Egypt; Female; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult	2014
Non-interventional study AI463-12 of real-world chronic HBV infection management--baseline characteristics and treatment patterns of Polish patients kohort. Przeglad epidemiologiczny, 2013, Volume: 67, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; Europe; Female; Guanine; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Longitudinal Studies; Male; Middle Aged; Organophosphonates; Poland; Practice Guidelines as Topic; Retrospective Studies; Socioeconomic Factors; Treatment Outcome	2013
First-line monotherapies of tenofovir and entecavir have comparable efficacies in hepatitis B treatment. European journal of gastroenterology & hepatology, 2014, Volume: 26, Issue:7 Topics: Adenine; Adolescent; Adult; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Young Adult	2014
Kinetics and prediction of HBsAg loss during long-term therapy with nucleos(t)ide analogues of different potency in patients with chronic hepatitis B. PloS one, 2014, Volume: 9, Issue:6 Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates	2014
Two-year treatment outcome of chronic hepatitis B infection treated with besifovir vs. entecavir: results from a multicentre study. Journal of hepatology, 2015, Volume: 62, Issue:3 Topics: Adult; Alanine Transaminase; Antiviral Agents; Carnitine; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Seroconversion; Time Factors; Treatment Outcome; Young Adult	2015
Tenofovir monotherapy versus tenofovir and entecavir combination therapy in adefovir-resistant chronic hepatitis B patients with multiple drug failure: results of a randomised trial. Gut, 2016, Volume: 65, Issue:6 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Republic of Korea; Tenofovir; Treatment Outcome	2016
Delayed Reduction of Hepatitis B Viral Load and Dynamics of Adefovir-Resistant Variants during Adefovir plus Entecavir Combination Rescue Therapy. International journal of medical sciences, 2015, Volume: 12, Issue:5 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome; Viral Load; Young Adult	2015
Cost-effectiveness analysis of lamivudine, telbivudine, and entecavir in treatment of chronic hepatitis B with adefovir dipivoxil resistance. Drug design, development and therapy, 2015, Volume: 9 Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Telbivudine; Thymidine	2015
[Treatment options in HBeAg-positive chronic hepatitis B patients with a poor response to 24-week interferon monotherapy]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2015, Volume: 35, Issue:6 Topics: Adenine; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Organophosphonates	2015
Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues. The Journal of infectious diseases, 2016, Jan-15, Volume: 213, Issue:2 Topics: Adenine; Adult; Amantadine; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Reproducibility of Results; RNA, Viral; Tenofovir; Virion	2016
[A randomized controlled trial on 240-week monotherapy with entecavir or adefovir in patients with chronic hepatitis B and cirrhosis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2015, Volume: 23, Issue:10 Topics: Adenine; Aged; Alanine Transaminase; alpha-Fetoproteins; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Organophosphonates; Time Factors	2015
Cost-effectiveness of Lamivudine, Telbivudine, Adefovir Dipivoxil and Entecavir on decompensated hepatitis B virus-related cirrhosis. European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:5 Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome	2016
Effect of nucleoside analogues in the treatment of hepatitis B cirrhosis and its effect on Th17 cell. European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:2 Topics: Adenine; Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Th17 Cells; Treatment Outcome	2017
Addition of nucleoside analogues to peg-IFNα-2a enhances virological response in chronic hepatitis B patients without early response to peg-IFNα-2a: a randomized controlled trial. BMC gastroenterology, 2017, Aug-30, Volume: 17, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Sustained Virologic Response	2017
Effects of the combined administration of entecavir and adefovir dipivoxil to improve hepatic fibrosis in hepatitis B patients with interferon resistance. Minerva medica, 2017, Volume: 108, Issue:6 Topics: Adenine; Aged; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Bilirubin; Creatinine; Drug Resistance, Viral; Drug Therapy, Combination; End Stage Liver Disease; Female; Gene Products, pol; Guanine; Hepatitis B, Chronic; Humans; Interferons; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Reverse Transcriptase Inhibitors; Severity of Illness Index	2017
Phase IV randomized clinical study: Peginterferon alfa-2a with adefovir or entecavir pre-therapy for HBeAg-positive chronic hepatitis B. Journal of the Formosan Medical Association = Taiwan yi zhi, 2018, Volume: 117, Issue:7 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Taiwan	2018
Efficacy and Safety of Besifovir Dipivoxil Maleate Compared With Tenofovir Disoproxil Fumarate in Treatment of Chronic Hepatitis B Virus Infection. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:9 Topics: Absorptiometry, Photon; Adult; Alanine Transaminase; Antiviral Agents; Bone Density; Bone Diseases, Metabolic; DNA, Viral; Double-Blind Method; Drug Resistance, Viral; Female; Glomerular Filtration Rate; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Hip; Humans; Lumbar Vertebrae; Male; Maleates; Middle Aged; Organophosphonates; Osteoporosis; Renal Insufficiency; Sustained Virologic Response; Tenofovir; Treatment Outcome	2019
Mitochondrial toxicity and body shape changes during nucleos(t)ide analogues administration in patients with chronic hepatitis B. Scientific reports, 2020, 02-06, Volume: 10, Issue:1 Topics: Adenine; Adiposity; Antiviral Agents; Cross-Sectional Studies; DNA, Mitochondrial; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Organophosphonates; RNA, Mitochondrial; Tenofovir	2020
Besifovir Dipivoxil Maleate 144-Week Treatment of Chronic Hepatitis B: An Open-Label Extensional Study of a Phase 3 Trial. The American journal of gastroenterology, 2020, Volume: 115, Issue:8 Topics: Adult; Antiviral Agents; Bone Density; Double-Blind Method; Drug Administration Schedule; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Republic of Korea; Tenofovir; Treatment Outcome; Viral Load	2020
Entecavir+tenofovir vs. lamivudine/telbivudine+adefovir in chronic hepatitis B patients with prior suboptimal response. Clinical and molecular hepatology, 2020, Volume: 26, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Sustained Virologic Response; Telbivudine; Tenofovir	2020
Continuing besifovir dipivoxil maleate versus switching from tenofovir disoproxil fumarate for treatment of chronic hepatitis B: Results of 192-week phase 3 trial. Clinical and molecular hepatology, 2021, Volume: 27, Issue:2 Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load	2021
Influence of Renal Function on the Single-Dose Pharmacokinetics of Besifovir, a Novel Antiviral Agent for theTreatment of Hepatitis B Virus Infection. Journal of clinical pharmacology, 2022, Volume: 62, Issue:1 Topics: Adult; Antiviral Agents; Area Under Curve; Female; Glomerular Filtration Rate; Guanine; Hepatitis B; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Models, Biological; Organophosphonates; Patient Acuity; Renal Insufficiency; Young Adult	2022

Other Studies

329 other study(ies) available for organophosphonates and guanine

Article	Year
Comparative activity of various compounds against clinical strains of herpes simplex virus. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:2 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Dextran Sulfate; Guanine; HeLa Cells; Heparin; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rabbits; Simplexvirus; Virus Replication	1992
The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model. Antiviral research, 1992, Volume: 18, Issue:1 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Line; Drug Resistance, Microbial; Female; Guanine; Herpesviridae Infections; Herpesvirus 1, Equid; Lung; Mice; Mice, Inbred BALB C; Mutation; Organophosphonates; Organophosphorus Compounds; Rabbits; Thymidine Kinase	1992
Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro. Antiviral research, 1990, Volume: 13, Issue:6 Topics: Adenine; Adenosine; Antiviral Agents; Cidofovir; Cytosine; DNA Viruses; Guanine; In Vitro Techniques; Nucleic Acid Synthesis Inhibitors; Nucleotides; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Structure-Activity Relationship; Tubercidin	1990
Inhibitory effect of (S)-HPMPC, (S)-HPMPA, and 2'-nor-cyclic GMP on clinical ocular adenoviral isolates is serotype-dependent in vitro. Antiviral research, 1991, Volume: 16, Issue:1 Topics: Adenine; Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; DNA; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Serotyping; Tumor Cells, Cultured; Viral Plaque Assay	1991
Synthesis and antiviral activity of (S)-9-[4-hydroxy-3-(phosphonomethoxy)butyl]guanine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:6 Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Viral Plaque Assay	1990
Selective inhibitory effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 2'-nor-cyclic GMP on adenovirus replication in vitro. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2 Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Fibroblasts; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Virus Replication	1987
The interaction of radioactive initiation factor IF-2 with ribosomes during initiation of protein synthesis. The Journal of biological chemistry, 1973, Jun-25, Volume: 248, Issue:12 Topics: Animals; Bacterial Proteins; Drug Stability; Escherichia coli; Formates; Glutaral; Guanine; Guanosine Triphosphate; Methionine; Models, Chemical; Muscles; Oligonucleotides; Organophosphonates; Peptide Initiation Factors; Phosphorus Isotopes; Protein Binding; Protein Kinases; Rabbits; Ribosomes; RNA, Messenger; RNA, Transfer	1973
Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus. Antiviral research, 1995, Volume: 26, Issue:1 Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Mice; Mice, SCID; Microbial Sensitivity Tests; Muromegalovirus; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds	1995
[Sensitivities to other antiviral drugs and thymidine kinase activity of aciclovir-resistant herpes simplex virus type 1]. Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:6 Topics: Acyclovir; Adenine; Antiviral Agents; Drug Resistance, Microbial; Ganciclovir; Guanine; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Thymidine Kinase; Vidarabine	1994
9-[(Phosphonoalkyl)benzyl]guanines. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Benzyl Compounds; Erythrocytes; Guanine; Humans; Kinetics; Organophosphonates; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship; Substrate Specificity	1993
The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells. Neoplasma, 1993, Volume: 40, Issue:6 Topics: Adenine; Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Guanine; Organophosphonates; Organophosphorus Compounds; Zidovudine	1993
Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase. Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4 Topics: Azaguanine; Enzyme Inhibitors; Erythrocytes; Guanine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Pteridines; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship	1996
MDL 74,968, a new acyclonucleotide analog: activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5 Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; DNA, Viral; Guanine; HIV Infections; HIV-1; HIV-2; Humans; Male; Mice; Mice, SCID; Monocytes; Organophosphonates; Spleen; T-Lymphocytes; Zidovudine	1996
Current and experimental therapeutic options for cytomegalovirus disease. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Apr-15, Volume: 53, Issue:8 Suppl 2 Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Foscarnet; Ganciclovir; Guanine; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds	1996
Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NM Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:3 Topics: Adenine; Animals; Animals, Newborn; Antiviral Agents; Cell Line; Fibroblasts; Guanine; Humans; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Retroviridae; Retroviridae Infections; Sarcoma Viruses, Murine; Tenofovir	1997
Intracellular metabolism and action of acyclic nucleoside phosphonates on DNA replication. Molecular pharmacology, 1997, Volume: 52, Issue:1 Topics: Adenine; Antineoplastic Agents; Cell Line; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Simian virus 40; Tenofovir	1997
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006 Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases	1997
Selection and characterisation of murine leukaemia L1210 cells with high-level resistance to the cytostatic activity of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl) adenine (PMEA). Biochimica et biophysica acta, 1998, Mar-12, Volume: 1402, Issue:1 Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Survival; Cyclic AMP; Drug Resistance, Neoplasm; Guanine; Kinetics; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Purine Nucleotides; Structure-Activity Relationship; Tumor Cells, Cultured	1998
Genotoxicity of purine acyclic nucleotide analogs. Folia biologica, 1997, Volume: 43, Issue:6 Topics: Adenine; Animals; Antiviral Agents; Cell Line; Female; Guanine; Humans; Male; Molecular Structure; Mutagenicity Tests; Mutagens; Organophosphonates; Organophosphorus Compounds; Purines; Rats; Rats, Inbred BN; Rats, Inbred Lew; Tenofovir; Teratogens; Thioguanine	1997
Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:6 Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Female; Guanine; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ointments; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine	1998
Comparison of antiviral compounds against human herpesvirus 6 and 7. Antiviral research, 1998, Volume: 40, Issue:1-2 Topics: Antiviral Agents; Cells, Cultured; Diphosphates; Guanine; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Leukocytes, Mononuclear; Organophosphonates; Ribonucleosides; Virus Replication	1998
Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3 Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Guanosine; Guinea Pigs; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Viral Plaque Assay; Virus Replication	1999
Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues. Biochemical pharmacology, 1999, Jun-15, Volume: 57, Issue:12 Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Guanine; Hepatitis B virus; Lamivudine; Microbial Sensitivity Tests; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Zalcitabine	1999
Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors. The Journal of clinical investigation, 1999, Volume: 103, Issue:12 Topics: Acyclovir; Adenine; Carcinoma, Hepatocellular; Drug Resistance, Microbial; Guanine; Hepatitis B virus; Humans; Lamivudine; Mutagenesis, Site-Directed; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Transfection; Tumor Cells, Cultured	1999
N6-cyclopropyl-PMEDAP: a novel derivative of 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) with distinct metabolic, antiproliferative, and differentiation-inducing properties. Biochemical pharmacology, 1999, Jul-15, Volume: 58, Issue:2 Topics: Adenine; Adenosine Deaminase; Adenosine Triphosphate; AMP Deaminase; Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Division; Deoxyadenine Nucleotides; Drug Interactions; Drug Screening Assays, Antitumor; Erythrocytes; Guanine; Humans; K562 Cells; Leukemia L1210; Mice; Organophosphonates; Organophosphorus Compounds; Pentostatin; Prodrugs; Rats; Tumor Cells, Cultured	1999
9-(2-phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine: a novel prodrug of 9-(2-phosphonylmethoxyethyl)guanine with improved antitumor efficacy and selectivity in choriocarcinoma-bearing rats. Oncology research, 1999, Volume: 11, Issue:4 Topics: Adenine; Animals; Antineoplastic Agents; Choriocarcinoma; Female; Guanine; Male; Organophosphonates; Organophosphorus Compounds; Pregnancy; Prodrugs; Rats; Tumor Cells, Cultured; Uterine Neoplasms	1999
9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis. Molecular pharmacology, 1999, Volume: 56, Issue:6 Topics: Adenine; Antineoplastic Agents; Deoxyadenine Nucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured	1999
In vitro antihepadnaviral activities of combinations of penciclovir, lamivudine, and adefovir. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cells, Cultured; Drug Interactions; Drug Therapy, Combination; Ducks; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Humans; Lamivudine; Liver; Organophosphonates; Virus Replication	2000
Lamivudine, adefovir and tenofovir exhibit long-lasting anti-hepatitis B virus activity in cell culture. Journal of viral hepatitis, 2000, Volume: 7, Issue:1 Topics: Acyclovir; Adenine; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Guanine; Hepatitis B virus; Lamivudine; Organophosphonates; Organophosphorus Compounds; Tenofovir; Tumor Cells, Cultured	2000
Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir. Journal of viral hepatitis, 2000, Volume: 7, Issue:2 Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Cell Line; Dioxolanes; DNA-Directed DNA Polymerase; DNA, Viral; Guanine; Hepatitis B virus; Humans; Organophosphonates; Organophosphorus Compounds; Purine Nucleosides; Tenofovir; Virus Replication	2000
Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC). Journal of virology, 2001, Volume: 75, Issue:10 Topics: Acyclovir; Adenine; Amino Acid Sequence; Antiviral Agents; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleotides; Drug Resistance, Microbial; Emtricitabine; Guanine; Hepatitis B virus; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Organophosphonates; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid	2001
Drugs for non-HIV viral infections. The Medical letter on drugs and therapeutics, 2002, Feb-04, Volume: 44, Issue:1123 Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Amantadine; Animals; Antiviral Agents; Cidofovir; Cytosine; Famciclovir; Foscarnet; Guanine; Herpesviridae Infections; Humans; Influenza, Human; Injections, Intravenous; Lamivudine; Organophosphonates; Organophosphorus Compounds; Rats; Ribavirin; Rimantadine; Thionucleotides; Trifluridine; Valacyclovir; Valine	2002
A new class of acyclic nucleoside phosphonates: synthesis and biological activity of 9-[[(phosphonomethyl)aziridin-1-yl]methyl]guanine (PMAMG) and analogues. Nucleosides, nucleotides & nucleic acids, 2002, Volume: 21, Issue:10 Topics: Alkylation; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antiviral Agents; Aziridines; Cell Line; Esterification; Guanine; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Shigella; Staphylococcus aureus; Streptococcaceae; Structure-Activity Relationship; Viruses; Yeasts	2002
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1. American journal of veterinary research, 2004, Volume: 65, Issue:4 Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication	2004
A novel class of phosphonate nucleosides. 9-[(1-phosphonomethoxycyclopropyl)methyl]guanine as a potent and selective anti-HBV agent. Journal of medicinal chemistry, 2004, May-20, Volume: 47, Issue:11 Topics: Animals; Antiviral Agents; Biological Availability; Cell Line; Crystallography, X-Ray; Dogs; Guanine; Hepatitis B; Hepatitis B virus; Herpesvirus 1, Human; HIV-1; Humans; Marmota; Molecular Structure; Nucleosides; Organophosphonates; Rats; Structure-Activity Relationship; Transfection	2004
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir? Antiviral research, 2004, Volume: 61, Issue:3 Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins	2004
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus. The Journal of general virology, 2005, Volume: 86, Issue:Pt 8 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication	2005
Chronic hepatitis B--treatment with nucleoside analogues. The Medical journal of Malaysia, 2005, Volume: 60 Suppl B Topics: Adenine; Drug Resistance; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Time Factors	2005
Synthesis of phosphonate analogues of the antiviral cyclopropane nucleoside A-5021. Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:8 Topics: Antiviral Agents; Cyclopropanes; Guanine; Organophosphonates	2005
N6-methyl-AMP aminohydrolase activates N6-substituted purine acyclic nucleoside phosphonates. Biochemical pharmacology, 2006, Apr-28, Volume: 71, Issue:9 Topics: Adenine; Aminohydrolases; Animals; Catalysis; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Guanine; In Vitro Techniques; Liver; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Rats, Sprague-Dawley	2006
Antiviral options for the treatment of chronic hepatitis B. The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:6 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates	2006
[The use of nucleotide analogues in treating patients with chronic hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2006, Volume: 14, Issue:5 Topics: Adenine; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates	2006
[Problems of and strategies in nucleotide analogues therapy for chronic hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2006, Volume: 14, Issue:5 Topics: Adenine; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates	2006
Hepatitis B virus with primary resistance to adefovir. The New England journal of medicine, 2006, Jul-20, Volume: 355, Issue:3 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Viral Load	2006
Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine. Antiviral chemistry & chemotherapy, 2006, Volume: 17, Issue:2 Topics: 2-Aminopurine; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Guanine; Herpesvirus 1, Human; Humans; Magnetic Resonance Spectroscopy; Organophosphonates; Spectrometry, Mass, Electrospray Ionization; Viral Plaque Assay	2006
Rescue therapy for lamivudine-resistant chronic hepatitis B: when and how? Hepatology (Baltimore, Md.), 2007, Volume: 45, Issue:2 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Salvage Therapy	2007
Antiviral therapy for pre- and post-liver transplantation patients with hepatitis B. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2007, Volume: 13, Issue:3 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Humans; Kidney Diseases; Lamivudine; Liver Transplantation; Organophosphonates; Secondary Prevention; Tenofovir	2007
Redetection of HBV lamivudine-resistant mutations in a patient under entecavir therapy, who had been treated sequentially with nucleos(t)ide analogues. Journal of medical virology, 2007, Volume: 79, Issue:11 Topics: Adenine; Adult; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors	2007
[New German and American guidelines for therapy of hepatitis B. Discrepancies and similarities]. Medizinische Klinik (Munich, Germany : 1983), 2007, Sep-15, Volume: 102, Issue:9 Topics: Adenine; Alanine Transaminase; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Guanine; Hepatitis B; Humans; Lamivudine; Liver; Liver Cirrhosis; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; United States	2007
[Recent therapies for hepatitis B (discussion)]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:10 Topics: Adenine; Antiviral Agents; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Organophosphonates	2007
Successful treatment of an entecavir-resistant hepatitis B virus variant. Journal of medical virology, 2007, Volume: 79, Issue:12 Topics: Adenine; Adult; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Mutation; Organophosphonates; Viral Load	2007
Hepatitis B: explosion of new knowledge. Gastroenterology, 2007, Volume: 133, Issue:5 Topics: Adenine; Antiviral Agents; Disease Progression; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Tolerance; Lamivudine; Organophosphonates	2007
Synthesis and evaluation of 9-deazaguanine derivatives as multi-substrate analogue inhibitors of PNP. Nucleic acids symposium series (2004), 2007, Issue:51 Topics: Animals; Cattle; Enzyme Inhibitors; Guanine; Humans; Organophosphonates; Purine-Nucleoside Phosphorylase	2007
Potency of tenofovir in chronic hepatitis B: mono or combination therapy? Journal of hepatology, 2008, Volume: 48, Issue:3 Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load	2008
[Acute hepatitis B: is antiviral therapy indicated? Two case reports]. Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:22 Topics: Acute Disease; Adenine; Adult; Algorithms; Antiviral Agents; Bilirubin; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Liver; Middle Aged; Organophosphonates; Prothrombin Time; Transaminases; Treatment Failure; Treatment Outcome	2008
Solid-phase synthesis of backbone-modified DNA analogs by the boranophosphotriester method using new protecting groups for nucleobases. Bioorganic & medicinal chemistry letters, 2008, Jul-01, Volume: 18, Issue:13 Topics: Boranes; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; DNA; Drug Design; Esters; Guanine; Mercaptoethanol; Models, Chemical; Molecular Biology; Molecular Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphonates; Phosphates	2008
Antiviral resistance mutations potentiate hepatitis B virus immune evasion through disruption of its surface antigen a determinant. Antiviral therapy, 2008, Volume: 13, Issue:3 Topics: Adenine; Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Multiple, Viral; Enzyme-Linked Immunosorbent Assay; Epitope Mapping; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; Gene Products, pol; Guanine; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunodominant Epitopes; Lamivudine; Mutagenesis, Site-Directed; Mutation; Organophosphonates; Transfection	2008
Selection of an entecavir-resistant mutant despite prolonged hepatitis B virus DNA suppression, in a chronic hepatitis B patient with preexistent lamivudine resistance: successful rescue therapy with tenofovir. European journal of gastroenterology & hepatology, 2008, Volume: 20, Issue:8 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Tenofovir; Viral Load	2008
Entecavir therapy for adefovir-resistant hepatitis B virus infection in kidney and liver allograft recipients. Transplantation, 2008, Aug-27, Volume: 86, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Kidney Transplantation; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Organophosphonates; Pilot Projects; Prothrombin Time	2008
9-Deazaguanine derivatives: synthesis and inhibitory properties as multi-substrate analogue inhibitors of mammalian PNPs. Nucleic acids symposium series (2004), 2008, Issue:52 Topics: Enzyme Inhibitors; Guanine; Humans; Organophosphonates; Purine-Nucleoside Phosphorylase	2008
Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors. Nucleic acids symposium series (2004), 2008, Issue:52 Topics: Adenine; Animals; Enzyme Inhibitors; Guanine; Organophosphonates; Organophosphorus Compounds; Purine-Nucleoside Phosphorylase; Spleen; Thermodynamics	2008
Phosphodiester-mediated reaction of cisplatin with guanine in oligodeoxyribonucleotides. Biochemistry, 2008, Dec-02, Volume: 47, Issue:48 Topics: Antineoplastic Agents; Base Sequence; Cisplatin; Cross-Linking Reagents; DNA; Esters; Guanine; Oligodeoxyribonucleotides; Organophosphonates; Thymidine Monophosphate	2008
Sensitivity and accuracy of an updated line probe assay (HBV DR v.3) in detecting mutations associated with hepatitis B antiviral resistance. Journal of hepatology, 2009, Volume: 50, Issue:1 Topics: Adenine; Adult; Antiviral Agents; DNA Probes; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Sensitivity and Specificity	2009
[Protocol for the antiviral therapy of chronic hepatitis B]. Orvosi hetilap, 2008, Dec-07, Volume: 149, Issue:49 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Lamivudine; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir	2008
Hepatitis B virus viral load and treatment decision. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:2 Topics: Adenine; Algorithms; Antiviral Agents; Decision Making; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis C, Chronic; Humans; Male; Organophosphonates; Patient Selection; RNA, Viral; Tenofovir; Viral Load	2009
Entecavir shows limited efficacy in HBeAg-positive hepatitis B patients with a partial virologic response to adefovir therapy. Journal of hepatology, 2009, Volume: 50, Issue:4 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; RNA, Viral; Treatment Outcome; Viral Load; Young Adult	2009
Partial virological response to nucleos(t)ide analogues in naïve patients with chronic hepatitis B: From guidelines to field practice. Journal of hepatology, 2009, Volume: 50, Issue:4 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Nucleotides; Organophosphonates; Tenofovir	2009
The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:4 Topics: Adenine; Anti-HIV Agents; Cell Line, Tumor; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Viral Proteins; Virus Replication	2009
Decision analysis model for hepatitis B prophylaxis one year after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2009, Volume: 15, Issue:4 Topics: Adenine; Administration, Oral; Antiviral Agents; Cost Savings; Cost-Benefit Analysis; Decision Support Techniques; Drug Costs; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Health Care Costs; Hepatitis B, Chronic; Humans; Immunoglobulins; Injections, Intramuscular; Lamivudine; Liver Transplantation; Markov Chains; Models, Economic; Organophosphonates; Retrospective Studies; Salvage Therapy; Secondary Prevention; Tenofovir; Time Factors; Treatment Failure; Treatment Outcome	2009
Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues. Antiviral chemistry & chemotherapy, 2009, Volume: 19, Issue:4 Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine	2009
Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity. Bioorganic & medicinal chemistry, 2009, Jun-01, Volume: 17, Issue:11 Topics: Animals; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Guanine; Humans; Inhibitory Concentration 50; Isomerism; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Organophosphonates; Simplexvirus	2009
Current trends in chronic hepatitis B management: results of a questionnaire. European journal of gastroenterology & hepatology, 2009, Volume: 21, Issue:10 Topics: Adenine; Adult; Antiviral Agents; Biopsy; Clinical Competence; Drug Administration Schedule; Family Health; Guanine; Hepatitis B e Antigens; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver; Male; Middle Aged; Organophosphonates; Practice Patterns, Physicians'; Spain; Surveys and Questionnaires	2009
Characterization of hepatitis B virus reverse transcriptase sequences in Chinese treatment naive patients. Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:8 Topics: Adenine; Adult; Antiviral Agents; Asian People; Base Composition; China; Computational Biology; Databases, Genetic; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Phenotype; Phylogeny; RNA-Directed DNA Polymerase; Treatment Failure; Virus Replication; Young Adult	2009
Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles. Journal of viral hepatitis, 2009, Volume: 16, Issue:12 Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Prognosis; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Young Adult	2009
Low efficacy of entecavir therapy in adefovir-refractory hepatitis B patients with prior lamivudine resistance. Journal of viral hepatitis, 2010, Volume: 17, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load	2010
Chronic hepatitis B: update 2009. Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:3 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Practice Guidelines as Topic; Tenofovir	2009
Hepatitis B in HIV patients: what is the current treatment and what are the challenges? Journal of HIV therapy, 2009, Volume: 14, Issue:1 Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Transaminases	2009
Two types of drug-resistant hepatitis B viral strains emerging alternately and their susceptibility to combination therapy with entecavir and adefovir. Antiviral therapy, 2009, Volume: 14, Issue:6 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Humans; Male; Middle Aged; Organophosphonates	2009
[The efficacy of nucleoside/nucleotide analogue on chronic hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:10 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication	2009
Evolution of hepatitis B virus mutation during entecavir rescue therapy in patients with antiviral resistance to lamivudine and adefovir. Antiviral therapy, 2009, Volume: 14, Issue:7 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Evolution, Molecular; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome	2009
1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state. Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1 Topics: Animals; Binding Sites; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Glutamic Acid; Glutamine; Glycine; Guanine; Organophosphonates; Phosphates; Protein Multimerization; Purine-Nucleoside Phosphorylase; Recombinant Proteins; Ribose	2010
Selection and counterselection of the rtI233V adefovir resistance mutation during antiviral therapy. Journal of clinical microbiology, 2010, Volume: 48, Issue:2 Topics: Adenine; Adult; Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Molecular Sequence Data; Mutation, Missense; Organophosphonates; Selection, Genetic; Sequence Alignment; Tenofovir; Treatment Failure; Viremia; Young Adult	2010
[Protocol for the antiviral therapy of hepatitis B and D]. Orvosi hetilap, 2010, Jan-03, Volume: 151, Issue:1 Topics: Adenine; Antiviral Agents; Biopsy; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis D; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Lamivudine; Liver Cirrhosis; Nucleotides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir	2010
Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells. Chemical biology & drug design, 2010, Volume: 75, Issue:4 Topics: Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Guanine; Humans; Kinetics; Leukemia; Lymphoma; Organophosphonates; Purine-Nucleoside Phosphorylase; Substrate Specificity	2010
Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Animals; Cattle; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Erythrocytes; Guanine; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Structure; Organophosphonates; Purine-Nucleoside Phosphorylase; Spleen; Stereoisomerism; Structure-Activity Relationship; Time Factors	2010
9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase. The FEBS journal, 2010, Volume: 277, Issue:7 Topics: Biochemistry; Cell Line, Tumor; Cell Membrane; Clodronic Acid; Endocytosis; Guanine; Humans; Jurkat Cells; Kinetics; Lymphocytes; Models, Chemical; Organophosphonates; Permeability; Protein Binding; Purine-Nucleoside Phosphorylase	2010
Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus. Antiviral research, 2010, Volume: 86, Issue:3 Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Mutation, Missense; Organophosphonates; Oxidation-Reduction; Sequence Analysis, DNA; Staining and Labeling; Tetrazolium Salts; Thymidine Kinase; Viral Proteins	2010
Antiproliferative effects of octadecyloxyethyl 9-[2-(phosphonomethoxy)ethyl]guanine against Me-180 human cervical cancer cells in vitro and in vivo. Chemotherapy, 2010, Volume: 56, Issue:1 Topics: Adenine; Animals; Antineoplastic Agents; Female; Guanine; HeLa Cells; Humans; Mice; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Uterine Cervical Neoplasms	2010
Coencapsulation of oxygen carriers and glucose oxidase in polyelectrolyte complex capsules for the enhancement of D-gluconic acid and delta-gluconolactone production. Artificial cells, blood substitutes, and immobilization biotechnology, 2010, Volume: 38, Issue:2 Topics: Alginates; Alkanes; Biocatalysis; Capsules; Cellulose; Dimethylpolysiloxanes; Drug Compounding; Fluorocarbons; Gluconates; Glucose Oxidase; Glucuronic Acid; Guanine; Hexuronic Acids; Lactones; Manganese Compounds; Nylons; Organophosphonates; Oxides; Oxygen; Solubility	2010
Liver transplantation in bearers of hepatitis B associated or not with delta hepatitis in the age of the new antiviral drugs: is hyperimmune globulin still necessary? Transplantation proceedings, 2010, Volume: 42, Issue:2 Topics: Adenine; Adult; Aged; Antiviral Agents; Aspartate Aminotransferases; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis D; Humans; Liver Transplantation; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Recurrence; Retrospective Studies; Young Adult	2010
Viral resistance in hepatitis B: prevalence and management. Current gastroenterology reports, 2010, Volume: 12, Issue:1 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genetic Testing; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Phenotype; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2010
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors. Antiviral therapy, 2010, Volume: 15, Issue:3 Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cells, Cultured; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine	2010
Cost-effectiveness of nucleoside analog therapy for hepatitis B in China: a Markov analysis. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2010, Volume: 13, Issue:5 Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Models, Economic; Models, Statistical; Monte Carlo Method; Nucleosides; Organophosphonates; Pyrimidinones; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Serologic Tests; Telbivudine; Thymidine	2010
Long-term outcome of renal transplant recipients with chronic hepatitis B infection-impact of antiviral treatments. Transplantation, 2010, Aug-15, Volume: 90, Issue:3 Topics: Adenine; Adult; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kidney Diseases; Kidney Transplantation; Lamivudine; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Viral Load	2010
Peptide nucleic acid array for detection of point mutations in hepatitis B virus associated with antiviral resistance. Journal of clinical microbiology, 2010, Volume: 48, Issue:9 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation, Missense; Oligonucleotide Array Sequence Analysis; Organophosphonates; Peptide Nucleic Acids; Point Mutation; Sensitivity and Specificity	2010
Acute hepatitis B infection associated with drug-resistant hepatitis B virus. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, Volume: 48, Issue:4 Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Organophosphonates; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Viral Proteins	2010
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: a target for anti-malarial chemotherapy. Molecular and biochemical parasitology, 2010, Volume: 173, Issue:2 Topics: Coenzymes; Enzyme Inhibitors; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Magnesium; Mass Spectrometry; Organophosphonates; Plasmodium falciparum; Plasmodium vivax; Protein Binding; Recombinant Proteins; Substrate Specificity	2010
Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy. Journal of viral hepatitis, 2011, Volume: 18, Issue:6 Topics: Adenine; Adult; Aged; Antiviral Agents; Asian People; DNA, Circular; DNA, Viral; Drug Resistance; Female; Gene Products, pol; Genetic Variation; Genome, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver; Liver Transplantation; Male; Middle Aged; Organophosphonates; Phylogeny; Tenofovir; Trans-Activators; Viral Envelope Proteins; Viral Regulatory and Accessory Proteins; Virus Replication	2011
Lamivudine plus adefovir or entecavir for patients with chronic hepatitis B resistant to lamivudine and adefovir. Journal of hepatology, 2010, Volume: 53, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genes, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Viral Load	2010
Rescue therapy for lamivudine-resistant chronic hepatitis B: comparison between entecavir 1.0 mg monotherapy, adefovir monotherapy and adefovir add-on lamivudine combination therapy. Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:8 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Republic of Korea; Retrospective Studies; Time Factors; Treatment Outcome; Viral Load; Virus Replication	2010
Cost-utility analysis of tenofovir disoproxil fumarate in the treatment of chronic hepatitis B. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2010, Volume: 13, Issue:8 Topics: Adenine; Cost-Benefit Analysis; Guanine; Hepatitis B, Chronic; Humans; Markov Chains; Organophosphonates; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; State Medicine; Tenofovir; United Kingdom	2010
Antiviral treatment including entecavir plus tenofovir disoproxil fumarate for HBV reactivation following a rituximab-based regimen. Antiviral therapy, 2010, Volume: 15, Issue:6 Topics: Adenine; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents; Drug Combinations; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lymphoma, Non-Hodgkin; Middle Aged; Organophosphonates; Rituximab; Tenofovir; Virus Activation	2010
HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy. Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:10 Topics: Adenine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Catheter Ablation; Disease-Free Survival; Female; Guanine; Hepatectomy; Hepatitis B Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Japan; Kaplan-Meier Estimate; Lamivudine; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organophosphonates; Proportional Hazards Models; Risk Assessment; Risk Factors; RNA, Viral; Survival Rate; Time Factors; Treatment Outcome	2010
[Antiviral treatment of chronic B hepatitis; 2010 - therapeutic recommendations]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010, Volume: 29, Issue:170 Topics: Adenine; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins; Tenofovir; Treatment Failure; Viral Load	2010
[Treatment of chronic hepatitis B. High response rate in general practice]. MMW Fortschritte der Medizin, 2010, Jul-22, Volume: 152, Issue:28-30 Topics: Adenine; Antiviral Agents; Cross-Sectional Studies; Germany; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Long-Term Care; Organophosphonates; Patient Care Team; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load	2010
Impact of hepatitis B e antigen-suppressing mutations on the replication efficiency of entecavir-resistant hepatitis B virus strains. Journal of viral hepatitis, 2011, Volume: 18, Issue:11 Topics: Adenine; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymorphism, Single Nucleotide; Tenofovir; Viral Load; Viral Proteins; Virus Replication	2011
Persistence and adherence to nucleos(t)ide analogue treatment for chronic hepatitis B. Journal of hepatology, 2011, Volume: 54, Issue:1 Topics: Adenine; Adolescent; Adult; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Young Adult	2011
Enhancing the antihepatitis B virus immune response by adefovir dipivoxil and entecavir therapies. Cellular & molecular immunology, 2011, Volume: 8, Issue:1 Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Case-Control Studies; Cytokines; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunomodulation; Lamivudine; Male; Middle Aged; Organophosphonates; T-Lymphocytes, Regulatory; Th1-Th2 Balance	2011
Efficacy and safety of entecavir and/or tenofovir for prophylaxis and treatment of hepatitis B recurrence post-liver transplant. Transplantation proceedings, 2010, Volume: 42, Issue:8 Topics: Adenine; Adult; Aged; Antiviral Agents; Combined Modality Therapy; Female; Guanine; Hepatitis B; Humans; Liver Transplantation; Male; Middle Aged; Organophosphonates; Secondary Prevention; Tenofovir	2010
Entecavir as treatment for reactivation of hepatitis B in immunosuppressed patients. World journal of gastroenterology, 2010, Nov-21, Volume: 16, Issue:43 Topics: Adenine; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome	2010
[Analogs combination therapy in chronic hepatitis B: when and how?]. Gastroenterologie clinique et biologique, 2010, Volume: 34 Suppl 2 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2010
[Long-term therapy for chronic hepatitis B in HIV co-infected patients]. Gastroenterologie clinique et biologique, 2010, Volume: 34 Suppl 2 Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine	2010
[Treatment has a positive impact on the long-term evolution of chronic hepatitis B]. Gastroenterologie clinique et biologique, 2010, Volume: 34 Suppl 2 Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Clinical Trials as Topic; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir	2010
Profile of HBV antiviral resistance mutations with distinct evolutionary pathways against nucleoside/nucleotide analogue treatment among Chinese chronic hepatitis B patients. Antiviral therapy, 2010, Volume: 15, Issue:8 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; China; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Typing; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Young Adult	2010
Evolution and suppression of HBV strains with multidrug resistance to lamivudine, adefovir dipivoxil and entecavir in a patient with chronic hepatitis B. Antiviral therapy, 2010, Volume: 15, Issue:8 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Evolution, Molecular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Organophosphonates; Phylogeny; Recombinant Proteins; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome	2010
Prevention of lamivudine-resistant hepatitis B recurrence after liver transplantation with entecavir plus tenofovir combination therapy and perioperative hepatitis B immunoglobulin only. Transplant infectious disease : an official journal of the Transplantation Society, 2011, Volume: 13, Issue:3 Topics: Adenine; Antiviral Agents; Combined Modality Therapy; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunization, Passive; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Perioperative Care; Secondary Prevention; Tenofovir; Treatment Outcome	2011
Treatment of HBeAg-negative chronic hepatitis B patients with nucleos(t)ide analogues. Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome	2011
Hyperlipidemic acute pancreatitis: a possible role of antiretroviral therapy with entecavir. Minerva anestesiologica, 2011, Volume: 77, Issue:10 Topics: Abdominal Pain; Acute Disease; Adenine; Adult; Alcoholism; Antiretroviral Therapy, Highly Active; Critical Care; Diabetes Mellitus, Type 2; Fever; Guanine; Hepatitis B, Chronic; Humans; Hyperlipidemias; Hypertriglyceridemia; Male; Organophosphonates; Pancreatitis; Plasmapheresis; Reverse Transcriptase Inhibitors; Tenofovir; Tomography, X-Ray Computed; Triglycerides	2011
Add-on adefovir is superior to a switch to entecavir as rescue therapy for Lamivudine-resistant chronic hepatitis B. Digestive diseases and sciences, 2011, Volume: 56, Issue:7 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load	2011
[Efficacy of entecavir and adefovir combination therapy in patients with chronic hepatitis B refractory to lamivudine and adefovir combination therapy]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:2 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates	2011
[Efficacy and treatment strategy for drug resistances of nucleos(t)ide analogues for chronic hepatitis B]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2011, Volume: 108, Issue:2 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir	2011
Comparison of multiplex restriction fragment mass polymorphism and sequencing analyses for detecting entecavir resistance in chronic hepatitis B. Antiviral therapy, 2011, Volume: 16, Issue:1 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mass Spectrometry; Mutation; Organophosphonates; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Viral Load	2011
Medication nonadherence with long-term management of patients with hepatitis B e antigen-negative chronic hepatitis B. Digestive diseases and sciences, 2011, Volume: 56, Issue:8 Topics: Adenine; Adult; Antiviral Agents; Asian People; Cohort Studies; Community Health Services; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Medication Adherence; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load	2011
Managing hepatitis B/HIV co-infected: adding entecavir to truvada (tenofovir disoproxil/emtricitabine) experienced patients. AIDS (London, England), 2011, May-15, Volume: 25, Issue:8 Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Deoxycytidine; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Treatment Outcome	2011
Proper antiviral therapy for hepatitis B virus-associated acute-on-chronic liver failure. Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:2 Topics: Adenine; Antiviral Agents; End Stage Liver Disease; Guanine; Hepatitis B, Chronic; Humans; Liver Failure, Acute; Organophosphonates; Tenofovir	2011
Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection. Journal of viral hepatitis, 2011, Volume: 18, Issue:4 Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Viral Proteins	2011
Two patterns of alanine aminotransferase increase to predict long-term viral response in chronic hepatitis B patients: virus- or host-induced? Antiviral therapy, 2011, Volume: 16, Issue:3 Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepacivirus; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-gamma; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Predictive Value of Tests; Pyrimidinones; T-Lymphocytes; Telbivudine; Thymidine; Treatment Outcome; Up-Regulation; Young Adult	2011
Predictors of relapse in chronic hepatitis B after discontinuation of anti-viral therapy. Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:3 Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Proportional Hazards Models; Real-Time Polymerase Chain Reaction; Recurrence; Time Factors	2011
Successful switch to tenofovir after suboptimal response to entecavir in an immunocompromised patient with chronic hepatitis B and without genotypic hepatitis B virus resistance. Infection, 2011, Volume: 39, Issue:4 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Bone Marrow; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Italy; Organophosphonates; Tenofovir; Treatment Outcome; Viremia	2011
Large-scale survey of naturally occurring HBV polymerase mutations associated with anti-HBV drug resistance in untreated patients with chronic hepatitis B. Journal of viral hepatitis, 2011, Volume: 18, Issue:7 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Mutation; Organophosphonates; Polyethylene Glycols; Recombinant Proteins	2011
Unsuccessful therapy with adefovir and entecavir-tenofovir in a patient with chronic hepatitis B infection with previous resistance to lamivudine: a fourteen-year evolution of hepatitis B virus mutations. BMC infectious diseases, 2011, Jun-22, Volume: 11 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Evolution, Molecular; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Middle Aged; Mutation; Organophosphonates; Tenofovir; Treatment Failure	2011
Serum HBsAg decline during long-term potent nucleos(t)ide analogue therapy for chronic hepatitis B and prediction of HBsAg loss. The Journal of infectious diseases, 2011, Aug-01, Volume: 204, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir	2011
Antiviral drug resistance testing in patients with chronic hepatitis B. Digestive diseases and sciences, 2012, Volume: 57, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Data Collection; Decision Making; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Surveys and Questionnaires; Tenofovir; Treatment Outcome; Viral Load	2012
Late onset of hepatitis B virus reactivation following hematopoietic stem cell transplantation: successful treatment with combined entecavir plus tenofovir therapy. Transplant infectious disease : an official journal of the Transplantation Society, 2012, Volume: 14, Issue:1 Topics: Adenine; Age of Onset; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hematopoietic Stem Cell Transplantation; Hepatitis B; Hepatitis B virus; Humans; Middle Aged; Organophosphonates; Tenofovir; Transplantation, Homologous; Treatment Outcome; Virus Activation	2012
Design, synthesis, and biological evaluation of triazolo-pyrimidine derivatives as novel inhibitors of hepatitis B virus surface antigen (HBsAg) secretion. Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16 Topics: Adenine; Animals; Antiviral Agents; Biological Availability; Drug Design; Drug Resistance, Viral; Guanine; Hep G2 Cells; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Male; Mice; Models, Chemical; Molecular Structure; Mutation; Organophosphonates; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tenofovir; Tetrazoles	2011
[Improvement of health-related quality of life in chronic hepatitis B patients treated with entecavir or adefovir]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2011, Volume: 19, Issue:4 Topics: Adenine; Adult; Aged; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Quality of Life; Young Adult	2011
The efficacy of entecavir therapy in chronic hepatitis B patients with suboptimal response to adevofir. Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:7 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Regression Analysis; Time Factors; Treatment Outcome; Viral Load	2011
Management options for lamivudine-resistant chronic hepatitis B patients with suboptimal virological suppression by adefovir. Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:8 Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2011
Long-term efficacy of entecavir therapy in chronic hepatitis B patients with antiviral resistance to lamivudine and adefovir. Journal of viral hepatitis, 2011, Volume: 18, Issue:10 Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome; Viral Load	2011
Long-term efficacy of entecavir in adefovir-refractory chronic hepatitis B patients with prior lamivudine resistance. Journal of viral hepatitis, 2011, Volume: 18, Issue:10 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Salvage Therapy; Treatment Outcome	2011
Design and synthesis of carbocyclic versions of furanoid nucleoside phosphonic Acid analogues as potential anti-hiv agents. Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:10 Topics: Adenine; Anti-HIV Agents; Cell Line; Drug Design; Furans; Guanine; HIV-1; Humans; Molecular Structure; Organophosphonates	2011
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Alkaline Phosphatase; Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Foscarnet; Ganciclovir; Genes, Reporter; Genotype; Guanine; Humans; Inhibitory Concentration 50; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication	2012
Adefovir-based combination therapy with entecavir or lamivudine for patients with entecavir-refractory chronic hepatitis B. Journal of medical virology, 2012, Volume: 84, Issue:1 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load	2012
Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: an international multicenter cohort study. Journal of hepatology, 2012, Volume: 56, Issue:3 Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Internationality; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Viremia; Young Adult	2012
Canadian patients with chronic hepatitis B cannot access appropriate drug treatments: a call for change. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2011, Volume: 25, Issue:10 Topics: Adenine; Antiviral Agents; Canada; Drug Approval; Guanine; Health Services Accessibility; Hepatitis B, Chronic; Humans; Insurance Coverage; Lamivudine; Liver Cirrhosis; National Health Programs; Organophosphonates; Tenofovir	2011
Synthesis of novel difluoro-cyclopropyl guanine nucleosides and their phosphonate analogues as potent antiviral agents. Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:11 Topics: Antiviral Agents; Cell Line; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Guanine; Halogenation; HIV Infections; HIV-1; Humans; Nucleosides; Organophosphonates	2011
Molecular characterization of a novel entecavir mutation pattern isolated from a multi-drug refractory patient with chronic hepatitis B infection. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2012, Volume: 53, Issue:2 Topics: Adenine; Adult; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Multiple, Viral; Fatal Outcome; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Mutation; Organophosphonates; Virus Replication	2012
Tenofovir plus entecavir as rescue therapy for multidrug-resistant chronic hepatitis B. Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Substitution; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Mutation; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load; Virus Replication	2012
Potent hepatitis B surface antigen response to treatment of hepatitis-B-e-antigen-positive chronic hepatitis B with α-interferon plus a nucleos(t)ide analog. Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:3 Topics: Adenine; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Time Factors; Young Adult	2012
Efficacy of entecavir and adefovir combination therapy for patients with lamivudine- and entecavir-resistant chronic hepatitis B. Digestive diseases and sciences, 2012, Volume: 57, Issue:5 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Middle Aged; Organophosphonates; Treatment Outcome; Viral Load; Virus Replication	2012
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2. Antiviral therapy, 2011, Volume: 16, Issue:8 Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Child; Child, Preschool; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Foscarnet; Genotype; Guanine; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Thymidine Kinase; Viral Proteins	2011
Antiviral efficacy of combination therapy with entecavir and adefovir for entecavir/lamivudine-resistant hepatitis B virus with or without adefovir resistance. Journal of medical virology, 2012, Volume: 84, Issue:3 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Outcome; Viral Load	2012
N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase. Journal of medicinal chemistry, 2012, Feb-23, Volume: 55, Issue:4 Topics: Cell Line, Tumor; Guanine; Guanine Nucleotides; Humans; Leukocytes, Mononuclear; Organophosphonates; Phosphorous Acids; Purine-Nucleoside Phosphorylase; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship	2012
Transarterial chemoembolization for hepatitis B virus-associated hepatocellular carcinoma: improved survival after concomitant treatment with nucleoside analogues. Journal of vascular and interventional radiology : JVIR, 2012, Volume: 23, Issue:3 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chi-Square Distribution; Disease-Free Survival; Female; Guanine; Hepatitis B, Chronic; Humans; Japan; Kaplan-Meier Estimate; Lamivudine; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Nucleosides; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; Time Factors; Treatment Outcome	2012
Entecavir plus adefovir combination treatment for chronic hepatitis B patients after failure of nucleoside/nucleotide analogues. Antiviral therapy, 2012, Volume: 17, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Combinations; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Treatment Failure; Viral Load	2012
High-resolution melting and real-time PCR for quantification and detection of drug-resistant HBV mutants in a single amplicon. Antiviral therapy, 2012, Volume: 17, Issue:2 Topics: Adenine; Antiviral Agents; DNA, Complementary; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Molecular Diagnostic Techniques; Nucleic Acid Denaturation; Organophosphonates; Pilot Projects; Polymerase Chain Reaction; Viral Load	2012
Response to tenofovir monotherapy in chronic hepatitis B patients with prior suboptimal response to entecavir. Journal of viral hepatitis, 2012, Volume: 19, Issue:3 Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Medication Adherence; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome; Young Adult	2012
[Hungarian consensus guideline for the diagnosis and treatment of B, C, and D viral hepatitis]. Orvosi hetilap, 2012, Mar-11, Volume: 153, Issue:10 Topics: Adenine; Antiviral Agents; Comorbidity; Consensus; Drug Administration Schedule; Drug Therapy, Combination; Genotype; Guanine; Hepacivirus; Hepatitis B; Hepatitis C; Hepatitis D; Humans; Hungary; Interferon-alpha; Interferons; Lamivudine; Oligopeptides; Organophosphonates; Polyethylene Glycols; Proline; Recombinant Proteins; Ribavirin; RNA, Viral; Tenofovir; Time Factors; Treatment Outcome	2012
Safety of long-term nucleos(t)ide treatment in chronic hepatitis B. Expert opinion on drug safety, 2012, Volume: 11, Issue:3 Topics: Adenine; Antiviral Agents; Drug Administration Schedule; Evidence-Based Medicine; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates; Patient Safety; Risk Assessment; Risk Factors; Tenofovir; Time Factors; Treatment Outcome	2012
Lamivudine plus adefovir vs. entecavir in HBeAg-positive hepatitis B with sequential treatment failure of lamivudine and adefovir. Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:7 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prognosis; Retrospective Studies; Treatment Failure	2012
Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction. Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8 Topics: Animals; Crystallography, X-Ray; Drug Design; Eukaryotic Initiation Factor-4E; Guanine; Guanosine Monophosphate; Humans; Inhibitory Concentration 50; Models, Molecular; Organophosphonates; Phosphorous Acids; Protein Biosynthesis; Rabbits; Reticulocytes; RNA Caps; Structure-Activity Relationship	2012
Similar risk of renal events among patients treated with tenofovir or entecavir for chronic hepatitis B. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2012, Volume: 10, Issue:8 Topics: Adenine; Adult; Aged; Antiviral Agents; Cohort Studies; Creatinine; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Kidney Diseases; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Assessment; Tenofovir; Young Adult	2012
Antiviral therapy against chronic hepatitis B in Brazil: high rates of lamivudine resistance mutations and correlation with HBV genotypes. Memorias do Instituto Oswaldo Cruz, 2012, Volume: 107, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Tenofovir; Viral Load; Young Adult	2012
High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B. The Korean journal of hepatology, 2012, Volume: 18, Issue:1 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates	2012
Commentary: combination therapy with two nucleos(t)ide analogues in chronic hepatitis B. Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:12 Topics: Adenine; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2012
Hepatitis B prophylaxis post liver transplantation with newer nucleos(t)ide analogues after hepatitis B immunoglobulin discontinuation. Transplant infectious disease : an official journal of the Transplantation Society, 2012, Volume: 14, Issue:5 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Nucleotides; Organophosphonates; Secondary Prevention; Tenofovir; Treatment Outcome; Young Adult	2012
Current practice of chronic hepatitis B treatment in Southern Italy. European journal of internal medicine, 2012, Volume: 23, Issue:5 Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Italy; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Patterns, Physicians'; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Young Adult	2012
Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues. Gastroenterology, 2012, Volume: 143, Issue:4 Topics: Adenine; Antiviral Agents; Cells, Cultured; DNA, Viral; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Interleukin-1; Lamivudine; Organophosphonates; T-Lymphocytes; Tenofovir; Tumor Necrosis Factor-alpha	2012
Comparison of the efficacy of tenofovir and entecavir for the treatment of nucleos(t)ide-naive patients with chronic hepatitis B. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2012, Volume: 23, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Young Adult	2012
Acute liver failure resulting from discontinuation of nucleoside analogues in chronic hepatitis B patients: a report of two cases. Scandinavian journal of infectious diseases, 2013, Volume: 45, Issue:2 Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Histocytochemistry; Humans; Lamivudine; Liver Failure, Acute; Liver Transplantation; Male; Medication Adherence; Necrosis; Organophosphonates; Telbivudine; Thymidine	2013
Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety. European journal of medicinal chemistry, 2012, Volume: 55 Topics: Animals; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA Viruses; Guanine; Humans; Hypoxanthine; Hypoxanthines; Nucleosides; Organophosphonates; Phosphorous Acids; Prodrugs; Structure-Activity Relationship	2012
Comparison of rescue strategies in lamivudine-resistant patients with chronic hepatitis B. Antiviral research, 2012, Volume: 96, Issue:2 Topics: Adenine; Adult; Antiviral Agents; China; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Salvage Therapy; Treatment Outcome	2012
Tenofovir monotherapy and tenofovir plus entecavir combination as rescue therapy for entecavir partial responders. Digestive diseases and sciences, 2012, Volume: 57, Issue:11 Topics: Adenine; Adult; Analysis of Variance; Antiviral Agents; Chi-Square Distribution; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Liver Function Tests; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome	2012
Evaluation of anti-HBV drug resistant mutations among patients with acute symptomatic hepatitis B in the United States. Journal of hepatology, 2013, Volume: 58, Issue:2 Topics: Acute Disease; Adenine; Adult; Antiviral Agents; Cohort Studies; Cross-Sectional Studies; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Male; Mutation; Organophosphonates; Retrospective Studies; Sequence Analysis, DNA; United States	2013
Genotype-specific mutations in the polymerase gene of hepatitis B virus potentially associated with resistance to oral antiviral therapy. Antiviral research, 2012, Volume: 96, Issue:3 Topics: Adenine; Administration, Oral; Amino Acid Substitution; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Genes, pol; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Mutation Rate; Organophosphonates; Prevalence; Virus Replication	2012
Long-term efficacy and safety of lamivudine, entecavir, and tenofovir for treatment of hepatitis B virus-related cirrhosis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013, Volume: 11, Issue:1 Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; Blood Chemical Analysis; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Turkey	2013
The 2012 revised Dutch national guidelines for the treatment of chronic hepatitis B virus infection. The Netherlands journal of medicine, 2012, Volume: 70, Issue:8 Topics: Adenine; Antiviral Agents; Drug Approval; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Netherlands; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Renal Insufficiency; Telbivudine; Tenofovir; Thymidine	2012
Multidrug-resistant hepatitis B virus resulting from sequential monotherapy with lamivudine, adefovir, and entecavir: clonal evolution during lamivudine plus adefovir therapy. Journal of medical virology, 2013, Volume: 85, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Clonal Evolution; DNA, Viral; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; RNA-Directed DNA Polymerase	2013
Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients: a propensity score analysis. Journal of hepatology, 2013, Volume: 58, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Fetoproteins; Antiviral Agents; Child; Child, Preschool; Female; Follow-Up Studies; Guanine; Hepatitis B Core Antigens; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Neoplasms; Male; Middle Aged; Organophosphonates; Proportional Hazards Models	2013
The efficacy of adefovir plus entecavir combination therapy in patients with chronic hepatitis B refractory to both lamivudine and adefovir. Digestive diseases and sciences, 2013, Volume: 58, Issue:5 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Failure	2013
The short-term efficacy of entecavir in lamivudine-resistant chronic hepatitis B: influence of sequential adefovir-refractoriness. Hepato-gastroenterology, 2013, Volume: 60, Issue:124 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome	2013
Treatment of lamivudine-resistant chronic hepatitis B infection: a multicenter retrospective study. Scandinavian journal of gastroenterology, 2013, Volume: 48, Issue:2 Topics: Adenine; Adult; Antiviral Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Logistic Models; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Retrospective Studies; Treatment Outcome; Viral Load	2013
Long-term hepatitis B surface antigen (HBsAg) kinetics during nucleoside/nucleotide analogue therapy: finite treatment duration unlikely. Journal of hepatology, 2013, Volume: 58, Issue:4 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Tenofovir	2013
Early viral suppression predicts good postoperative survivals in patients with hepatocellular carcinoma with a high baseline HBV-DNA load. Annals of surgical oncology, 2013, Volume: 20, Issue:5 Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Disease-Free Survival; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Organophosphonates; Portal Vein; Proportional Hazards Models; Retrospective Studies; Risk Factors; Viral Load	2013
Management of chronic hepatitis B: Canadian Association for the Study of the Liver consensus guidelines. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2012, Volume: 26, Issue:12 Topics: Adenine; Allied Health Personnel; Antibodies, Viral; Antiviral Agents; Canada; Coinfection; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C; Humans; Interferons; Kidney Diseases; Liver; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Tenofovir	2012
Experience of anti-viral therapy in hepatitis B-associated membranous nephropathy, including Lamivudine-resistant strains. The Korean journal of internal medicine, 2012, Volume: 27, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Glomerulonephritis, Membranous; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult	2012
Should chronic hepatitis B be treated as early as possible? International journal of technology assessment in health care, 2013, Volume: 29, Issue:1 Topics: Adenine; Adult; Antiviral Agents; Belgium; Cost-Benefit Analysis; Early Diagnosis; Guanine; Health Care Surveys; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Markov Chains; Middle Aged; Organophosphonates; Quality of Life; Secondary Prevention; Tenofovir; Treatment Outcome; Viral Load	2013
[Antiviral therapy for patients with chronic hepatitis B with multi-drug resistance to nucleoside analogues]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2013, Volume: 110, Issue:1 Topics: Adenine; Aged; Aged, 80 and over; Antiviral Agents; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates	2013
Kinetics and prediction of HBsAg loss during therapy with analogues in patients affected by chronic hepatitis B HBeAg negative and genotype D. Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:4 Topics: Adenine; Aged; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2013
Outcome of various treatments for posttransplant hepatitis B virus recurrence. World journal of surgery, 2013, Volume: 37, Issue:4 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Biomarkers; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Recurrence; Retrospective Studies; Treatment Outcome; Young Adult	2013
High frequency of complex mutational patterns in lamivudine resistant hepatitis B virus isolates. Journal of medical virology, 2013, Volume: 85, Issue:5 Topics: Adenine; Antiviral Agents; Codon, Nonsense; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation, Missense; Organophosphonates; RNA-Directed DNA Polymerase	2013
Individualized treatment of HBeAg-negative chronic hepatitis B using pegylated interferon-α2a as first-line and week-12 HBV DNA/HBsAg stopping rule: a cost-effectiveness analysis. Antiviral therapy, 2013, Volume: 18, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Cost-Benefit Analysis; Drug Administration Schedule; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Liver Neoplasms; Male; Markov Chains; Organophosphonates; Polyethylene Glycols; Precision Medicine; Prognosis; Quality-Adjusted Life Years; Recombinant Proteins; Tenofovir; Viral Load	2013
[Cost-effectiveness of nucleoside/nucleotide analogues in chronic hepatitis B]. Revista de saude publica, 2012, Volume: 46, Issue:6 Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Markov Chains; Models, Theoretical; Organophosphonates; Quality-Adjusted Life Years; Tenofovir	2012
Increased eGFR with telbivudine in combination therapy of chronic hepatitis B infection. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2014, Volume: 33, Issue:1 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Telbivudine; Tenofovir; Thymidine	2014
Prevention of de novo hepatitis B with adefovir plus vaccination in recipients of liver transplants from core antibody-positive donors. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2013, Volume: 19, Issue:4 Topics: Adenine; Adult; Aged; Antiviral Agents; Biomarkers; Deoxycytidine; DNA, Viral; Drug Substitution; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Core Antigens; Hepatitis B Vaccines; Hepatitis B virus; Humans; Liver Transplantation; Middle Aged; Organophosphonates; Tenofovir; Time Factors; Tissue Donors; Treatment Outcome	2013
Prevention of de novo hepatitis B in recipients of core antibody-positive livers with lamivudine and other nucleos(t)ides: a 12-year experience. Transplantation, 2013, Apr-15, Volume: 95, Issue:7 Topics: Adenine; Adult; Aged; Analysis of Variance; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Donor Selection; Female; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunosuppressive Agents; Lamivudine; Liver Transplantation; Logistic Models; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Tenofovir; Time Factors; Tissue Donors; Treatment Outcome; Viral Load	2013
Chronic hepatitis B treatment initiation and modification patterns in five European countries: a 2-year longitudinal, non-interventional study. Antiviral therapy, 2014, Volume: 19, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antiviral Agents; Disease Management; DNA, Viral; Europe; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Longitudinal Studies; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Tenofovir	2014
Snapshot on drug-resistance rate and profiles in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice. Journal of medical virology, 2013, Volume: 85, Issue:6 Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Recurrence; Telbivudine; Thymidine; Treatment Outcome	2013
Oral nucleoside/nucleotide analogs without hepatitis B immune globulin after liver transplantation for hepatitis B. The American journal of gastroenterology, 2013, Volume: 108, Issue:6 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Postoperative Care; Proportional Hazards Models; Secondary Prevention; Survival Rate; Viral Load; Young Adult	2013
Comparison of re-treatment outcomes of lamivudine plus adefovir or entecavir in chronic hepatitis B patients with viral relapse after cessation of adefovir. European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:9 Topics: Adenine; Adult; Antiviral Agents; Case-Control Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Male; Organophosphonates; Prospective Studies; Recurrence; Treatment Outcome	2013
Entecavir plus adefovir rescue therapy for chronic hepatitis B patients after multiple treatment failures in real-life practice. Virology journal, 2013, May-25, Volume: 10 Topics: Adenine; Adult; Antiviral Agents; Creatine Kinase; Creatinine; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Salvage Therapy; Treatment Outcome; Viral Load	2013
Prophylaxis in HBV-infected liver transplant patients: end of the HBIG era? The American journal of gastroenterology, 2013, Volume: 108, Issue:6 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Transplantation; Male; Organophosphonates	2013
Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9 Topics: Adenine; Arabinofuranosyluracil; DNA, Viral; Guanine; HEK293 Cells; Hepatitis B virus; Humans; Organophosphonates; Protein Binding; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tenofovir; Viral Proteins	2013
Living related liver transplantation for hepatitis B-related liver disease without hepatitis B immune globulin prophylaxis. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2013, Volume: 19, Issue:9 Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins; Immunosuppression Therapy; Immunosuppressive Agents; Lamivudine; Liver Transplantation; Living Donors; Male; Middle Aged; Organophosphonates; Prospective Studies; Recurrence; Tenofovir; Treatment Outcome	2013
WHO survey finds half of countries do not have clinical guidelines for treating hepatitis. BMJ (Clinical research ed.), 2013, Jul-24, Volume: 347 Topics: Adenine; Antiviral Agents; Drugs, Essential; Global Health; Guanine; Health Priorities; Hepatitis B; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins; Tenofovir; World Health Organization	2013
[Detection of resistance mutations in chronic hepatitis B patients receiving antiviral therapy for over one year]. Mikrobiyoloji bulteni, 2013, Volume: 47, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Polymerase Chain Reaction; Young Adult	2013
[HBV vaccine escape mutations in a chronic hepatitis B patient treated with nucleos(t)ide analogues]. Mikrobiyoloji bulteni, 2013, Volume: 47, Issue:3 Topics: Adenine; Biopsy; Drug Resistance, Multiple, Viral; Female; Genes, pol; Guanine; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver; Middle Aged; Mutation; Nucleosides; Nucleotides; Organophosphonates; Tenofovir	2013
Long-term efficacy of entecavir plus adefovir combination therapy versus entecavir monotherapy in adefovir refractory chronic hepatitis B patients with prior lamivudine resistance. Intervirology, 2014, Volume: 57, Issue:1 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome	2014
Combination lamivudine and adefovir versus entecavir for the treatment of naïve chronic hepatitis B patients: a pilot study. Medical science monitor : international medical journal of experimental and clinical research, 2013, Sep-09, Volume: 19 Topics: Adenine; Adult; Alanine Transaminase; Analysis of Variance; Aspartate Aminotransferases; Bilirubin; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Pilot Projects	2013
Comparison of tenofovir and entecavir in patients with chronic HBV infection. European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:18 Topics: Adenine; Adult; Aged; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir	2013
Efficacy of adefovir-based combination therapy for patients with Lamivudine- and entecavir-resistant chronic hepatitis B virus infection. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Adenine; Adult; Aged; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome	2013
Oral antiviral therapy for hepatitis B: the case of besifovir, a new kid on the block with a long way to go. Gut, 2014, Volume: 63, Issue:6 Topics: Antibodies, Viral; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates	2014
Chronic hepatitis B monitoring and treatment patterns in five European countries with different access and reimbursement policies. Antiviral therapy, 2014, Volume: 19, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Europe; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Hospitalization; Humans; Insurance, Health, Reimbursement; Interferon-alpha; Lamivudine; Longitudinal Studies; Male; Middle Aged; Monitoring, Ambulatory; Organophosphonates; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Tenofovir	2014
Incorporated antivirals for chronic hepatitis B in Brazil: a cost-effectiveness analysis. Revista de saude publica, 2013, Volume: 47, Issue:4 Topics: Adenine; Adult; Analysis of Variance; Antiviral Agents; Brazil; Cost-Benefit Analysis; Disease Progression; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Organophosphonates; Tenofovir; Treatment Outcome	2013
Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3 Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytosine; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genotype; Guanine; Mutation; Organophosphonates	2014
Lamivudine compared with newer antivirals for prophylaxis of hepatitis B core antibody positive livers: a cost-effectiveness analysis. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2014, Volume: 14, Issue:3 Topics: Adenine; Antiviral Agents; Cohort Studies; Cost-Benefit Analysis; Decision Trees; Follow-Up Studies; Graft Survival; Guanine; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Core Antigens; Hepatitis B virus; Humans; Lamivudine; Liver Transplantation; Markov Chains; Organophosphonates; Prognosis; Quality-Adjusted Life Years; Survival Rate; Tenofovir	2014
Efficacy of 2years of entecavir plus adefovir therapy in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analog treatment. Antiviral research, 2014, Volume: 103 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Retrospective Studies; Salvage Therapy; Treatment Outcome	2014
Tenofovir is superior to entecavir for achieving complete viral suppression in HBeAg-positive chronic hepatitis B patients with high HBV DNA. Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:6 Topics: Adenine; Adult; Antiviral Agents; California; Cohort Studies; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome	2014
Dynamic comparison between Daan real-time PCR and Cobas TaqMan for quantification of HBV DNA levels in patients with CHB. BMC infectious diseases, 2014, Feb-14, Volume: 14 Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Prospective Studies; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Viral Load; Young Adult	2014
Generation of a human hepatoma cell line supporting efficient replication of a lamivudine resistant hepatitis B virus. Journal of virological methods, 2014, Volume: 201 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hep G2 Cells; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Organophosphonates; Tenofovir; Virus Replication	2014
Successful withdrawal of antiviral treatment in kidney transplant recipients with chronic hepatitis B viral infection. Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:2 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Kidney Transplantation; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Time Factors; Virus Activation; Withholding Treatment	2014
[Diagnosis and treatment of chronic hepatitis B and D. Hungarian national consensus guideline]. Orvosi hetilap, 2014, Volume: 155 Suppl Topics: Adenine; Antiviral Agents; Consensus; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis D, Chronic; Hepatitis Delta Virus; Humans; Hungary; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir	2014
Commentary: tenofovir is superior to entecavir in HBeAg-positive chronic hepatitis B patients. Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:9 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir	2014
Commentary: tenofovir is superior to entecavir in HBeAg-positive chronic hepatitis B patients--authors' reply. Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:9 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir	2014
Effects of entecavir on peripheral blood lymphocyte profiles in chronic hepatitis B patients with suboptimal responses to adefovir. Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:7 Topics: Adenine; Antiviral Agents; B-Lymphocytes; Case-Control Studies; CD4-Positive T-Lymphocytes; DNA, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Tumor Necrosis Factor Receptor Superfamily, Member 7; Viral Load	2014
Letter: Treatment of HBeAg+ chronic hepatitis B--is tenofovir truly superior to entecavir? Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:11 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir	2014
Letter: Treatment of HBeAg+ chronic hepatitis B--is tenofovir truly superior to entecavir? Authors' reply. Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:11 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Tenofovir	2014
Coexistence of HBsAg and HBsAb in a difficult-to-treat chronic hepatitis B: loss of HBsAg with entecavir plus tenofovir combination. BMC gastroenterology, 2014, May-17, Volume: 14 Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Organophosphonates; Recombinant Proteins; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load	2014
New nucleos(t)ide analogue monoprophylaxis after cessation of hepatitis B immunoglobulin is effective against hepatitis B recurrence. Transplant international : official journal of the European Society for Organ Transplantation, 2014, Volume: 27, Issue:10 Topics: Adenine; Adult; Cohort Studies; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Guanine; Hepatitis B, Chronic; Humans; Immunoglobulins; Immunosuppressive Agents; Liver Cirrhosis; Liver Transplantation; Male; Organophosphonates; Prospective Studies; Recurrence; Retreatment; Risk Assessment; Statistics, Nonparametric; Tenofovir; Transplantation Immunology; Treatment Outcome	2014
Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection. Antiviral therapy, 2015, Volume: 20, Issue:2 Topics: Adenine; Adult; Antiviral Agents; China; Clone Cells; Drug Resistance, Viral; Female; Gene Expression; Genotype; Guanine; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Organophosphonates; Phenotype; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Viral Proteins	2015
Adefovir and lamivudine combination therapy in patients with entecavir-resistant chronic hepatitis B: antiviral responses and evolution of mutations. Intervirology, 2014, Volume: 57, Issue:5 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Prospective Studies; Serum; Treatment Outcome; Viral Load	2014
Antiviral therapy of chronic hepatitis B. Intervirology, 2014, Volume: 57, Issue:3-4 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication	2014
Reduction of infectivity in chronic hepatitis B virus carriers among healthcare providers and pregnant women by antiviral therapy. Intervirology, 2014, Volume: 57, Issue:3-4 Topics: Adenine; Antiviral Agents; DNA, Viral; Female; Guanine; Health Personnel; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Professional-to-Patient; Infectious Disease Transmission, Vertical; Lamivudine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Viral Load; Viremia	2014
Mechanisms of hepatitis B virus resistance development. Intervirology, 2014, Volume: 57, Issue:3-4 Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Deoxycytidine; Drug Resistance, Multiple, Viral; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Virus Replication	2014
Hepatitis B virus drug resistance tools: one sequence, two predictions. Intervirology, 2014, Volume: 57, Issue:3-4 Topics: Adenine; Antiviral Agents; Base Sequence; Drug Resistance, Multiple, Viral; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Evasion; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Tenofovir; Thymidine	2014
Virologic breakthrough in a patient with chronic hepatitis B by combination treatment with tenofovir disoproxil fumarate and entecavir. Drug design, development and therapy, 2014, Volume: 8 Topics: Adenine; Amino Acid Substitution; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome	2014
Treatment cessation in noncirrhotic, e-antigen negative chronic hepatitis B is safe and effective following prolonged anti-viral suppression with nucleosides/nucleotides. Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:7 Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Recurrence; Tenofovir; Withholding Treatment; Young Adult	2014
Efficacy and safety of tenofovir in a kidney transplant patient with chronic hepatitis B and nucleos(t)ide multidrug resistance: a case report. Journal of medical case reports, 2014, Aug-21, Volume: 8 Topics: Adenine; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Kidney Transplantation; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load	2014
Efficacy of entecavir-tenofovir combination therapy for chronic hepatitis B patients with multidrug-resistant strains. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:11 Topics: Adenine; Adult; Aged; Antiviral Agents; Base Sequence; Cohort Studies; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Tenofovir; Treatment Outcome; Viral Load; Young Adult	2014
Incidence and predictors of hepatocellular carcinoma in Caucasian chronic hepatitis B patients receiving entecavir or tenofovir. Journal of hepatology, 2015, Volume: 62, Issue:2 Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Greece; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Netherlands; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Risk Factors; Spain; Tenofovir; Time Factors; Turkey; White People	2015
[Retrospective analysis of the efficacy and safety of anti-hepatitis B virus drugs taken during pregnancy in women from the Guangdong Province]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2014, Volume: 22, Issue:7 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Mothers; Organophosphonates; Pregnancy; Retrospective Studies; Telbivudine; Thymidine; Time Factors	2014
Synthesis and antiretroviral activity of novel 4'-fluoro-5'-deoxyphosphonic acid carbocyclic nucleoside analogs. Nucleosides, nucleotides & nucleic acids, 2014, Volume: 33, Issue:10 Topics: Acids, Carbocyclic; Anti-HIV Agents; Drug Design; Fluorine; Glyceraldehyde; Guanine; HIV-1; Organophosphonates; Purine Nucleotides; Structure-Activity Relationship	2014
The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy. Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:11-12 Topics: Adenine; Adult; Antiviral Agents; Canada; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Nucleosides; Organophosphonates; Retrospective Studies; Risk Factors; Telbivudine; Tenofovir; Thymidine	2014
Long-term outcomes of two rescue therapies in lamivudine-refractory patients with chronic hepatitis B: combined lamivudine and adefovir, and 1-mg entecavir. Clinical and molecular hepatology, 2014, Volume: 20, Issue:3 Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Treatment Outcome	2014
Tenofovir-induced Fanconi syndrome in chronic hepatitis B monoinfected patients that reverted after tenofovir withdrawal. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2014, Volume: 61, Issue:4 Topics: Adenine; Antiviral Agents; Fanconi Syndrome; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Treatment Outcome; Viral Load; Withholding Treatment	2014
Do we need more nucleos(t)ide analogs for the treatment of chronic hepatitis B? Journal of hepatology, 2015, Volume: 62, Issue:3 Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Organophosphonates	2015
[Tenofovir rescue therapy for chronic hepatitis B patients after suboptimal response to treatment with lamivudine plus adefovir dipivoxil]. Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:9 Topics: Adenine; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Failure; Treatment Outcome	2014
HBV carrying drug-resistance mutations in chronically infected treatment-naive patients. Antiviral therapy, 2015, Volume: 20, Issue:4 Topics: Adenine; Antibodies, Viral; Antiviral Agents; Brazil; DNA, Viral; Drug Resistance, Viral; Gene Products, pol; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation; Organophosphonates; Retrospective Studies; Sequence Analysis, DNA; Tenofovir; Virus Replication	2015
Low-dose short-term hepatitis B immunoglobulin with high genetic barrier antivirals: the ideal post-transplant hepatitis B virus prophylaxis? Transplant infectious disease : an official journal of the Transplantation Society, 2015, Volume: 17, Issue:3 Topics: Adenine; Adult; Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Prospective Studies; Recurrence; Tenofovir	2015
Comparison of the efficacies of entecavir 0.5 and 1.0 mg combined with adefovir in patients with chronic hepatitis B who had failed on prior nucleos(t)ide analogue treatments. Journal of medical virology, 2015, Volume: 87, Issue:6 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Republic of Korea; Retrospective Studies; Time Factors; Treatment Failure; Treatment Outcome; Viral Load; Young Adult	2015
Analysis of HBV genotype, drug resistant mutations, and pre-core/basal core promoter mutations in Korean patients with acute hepatitis B. Journal of medical virology, 2015, Volume: 87, Issue:6 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B; Hepatitis B Core Antigens; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Promoter Regions, Genetic; Prospective Studies; Republic of Korea; Viral Core Proteins; Virus Replication	2015
Tenofovir rescue regimen following prior suboptimal response to entecavir and adefovir combination therapy in chronic hepatitis B patients exposed to multiple treatment failures. Journal of medical virology, 2015, Volume: 87, Issue:6 Topics: Adenine; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; High-Throughput Nucleotide Sequencing; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; ROC Curve; Tenofovir; Treatment Failure; Treatment Outcome	2015
Clinical course of chronic hepatitis B patients receiving nucleos(t)ide analogues after virological breakthrough during monotherapy with lamivudine. The new microbiologica, 2015, Volume: 38, Issue:1 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; Viral Load; Viral Matrix Proteins; Young Adult	2015
[Pharmacoeconomic evaluation of treatments based on antiretrovirals for HBeAg-negative chronic hepatitis B]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2015, Volume: 23, Issue:1 Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Economics, Pharmaceutical; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Polyethylene Glycols; Quality-Adjusted Life Years; Recombinant Proteins	2015
Limited hepatitis B immunoglobulin with potent nucleos(t)ide analogue is a cost-effective prophylaxis against hepatitis B virus after liver transplantation. Transplantation proceedings, 2015, Volume: 47, Issue:2 Topics: Adenine; Adult; Aged; Antiviral Agents; Cost-Benefit Analysis; Drug Costs; Female; Graft Survival; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Humans; Immunoglobulins; Liver Transplantation; Male; Middle Aged; Organophosphonates; Retrospective Studies; Tenofovir; Treatment Outcome; United States	2015
Early kidney injury during long-term adefovir dipivoxil therapy for chronic hepatitis B. World journal of gastroenterology, 2015, Mar-28, Volume: 21, Issue:12 Topics: Acute Kidney Injury; Adenine; Adult; Antiviral Agents; beta 2-Microglobulin; Biomarkers; Case-Control Studies; Creatinine; Drug Substitution; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Predictive Value of Tests; Prospective Studies; Retinol-Binding Proteins; Risk Factors; Time Factors; Treatment Outcome	2015
Clonal evolution of multidrug resistant hepatitis B virus during entecavir rescue therapy. Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:11 Topics: Adenine; Adult; Antiviral Agents; Clonal Evolution; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Viral Load	2015
Impact of nucleos(t)ide analogue combination therapy on the estimated glomerular filtration rate in patients with chronic hepatitis B. Medicine, 2015, Volume: 94, Issue:15 Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine	2015
A case of entecavir resistance which is developed after complete viral suppression during entecavir treatment for nucleoside-naive chronic hepatitis B. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2014, Volume: 25 Suppl 1 Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Remission Induction; Tenofovir	2014
Response to potent anti-HBV agents in chronic hepatitis B and combined effect of HBV reverse transcriptase mutations. Gene, 2015, Aug-01, Volume: 567, Issue:1 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Mutation; Organophosphonates; RNA-Directed DNA Polymerase; Tenofovir	2015
Entecavir Combined With Adefovir Ameliorates Patients With Chronic Hepatitis B Who Fail to Respond to Nucleotide (Acid) Analog Monotherapy. American journal of therapeutics, 2017, Volume: 24, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome	2017
Nucleoside-Nucleotide Analog Combination Therapy Is Effective in Preventing Recurrent Hepatitis B After Liver Transplantation. Digestive diseases and sciences, 2015, Volume: 60, Issue:9 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Prospective Studies; Recurrence; Tenofovir	2015
Tenofovir-based rescue therapy for chronic hepatitis B patients who had failed treatment with lamivudine, adefovir, and entecavir. Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:10 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Tenofovir; Treatment Failure	2015
Prevalence and types of drug-resistant variants in Chinese patients with acute hepatitis B. Journal of medical virology, 2015, Volume: 87, Issue:9 Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Genetic Variation; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; Prevalence; RNA-Directed DNA Polymerase; Telbivudine; Thymidine; Time Factors; Young Adult	2015
Comparison of entecavir monotherapy and de novo lamivudine and adefovir combination therapy in HBeAg-positive chronic hepatitis B with high viral load: 48-week result. Clinical and experimental medicine, 2016, Volume: 16, Issue:3 Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Blood; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Treatment Outcome; Viral Load; Young Adult	2016
Design, Synthesis, and Evaluation of Anti-HBV Activity of Hybrid Molecules of Entecavir and Adefovir: Exomethylene Acycloguanine Nucleosides and Their Monophosphate Derivatives. Nucleosides, nucleotides & nucleic acids, 2015, Volume: 34, Issue:8 Topics: Adenine; Antiviral Agents; Drug Design; Guanine; Hep G2 Cells; Hepatitis B virus; Humans; In Vitro Techniques; Organophosphonates	2015
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance. PloS one, 2015, Volume: 10, Issue:8 Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Arabinofuranosyluracil; Cell Line, Tumor; Drug Resistance, Multiple, Viral; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Models, Molecular; Organophosphonates; Tenofovir; Virus Replication	2015
Mechanism of Adefovir, Tenofovir and Entecavir Resistance: Molecular Modeling Studies of How A Novel Anti-HBV Agent (FMCA) Can Overcome the Drug Resistance. Current medicinal chemistry, 2015, Volume: 22, Issue:34 Topics: Adenine; Adenosine; Amino Acid Sequence; Antiviral Agents; Binding Sites; Catalytic Domain; Databases, Protein; Drug Resistance, Viral; Gene Products, pol; Guanine; Hepatitis B; Hepatitis B virus; HIV Reverse Transcriptase; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Organophosphonates; Sequence Alignment; Tenofovir	2015
Long-term follow-up of HBsAg-positive patients in Germany. European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:1 Topics: Adenine; Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Mass Screening; Middle Aged; Organophosphonates; Prognosis; Prospective Studies; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Time Factors; Turkey	2016
Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies. World journal of gastroenterology, 2015, Oct-14, Volume: 21, Issue:38 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Viral Load; Young Adult	2015
Entecavir plus tenofovir versus entecavir plus adefovir in chronic hepatitis B patients with a suboptimal response to lamivudine and adefovir combination therapy. Clinical and molecular hepatology, 2015, Volume: 21, Issue:3 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Odds Ratio; Organophosphonates; Real-Time Polymerase Chain Reaction; Retrospective Studies; Tenofovir; Viral Load	2015
Comprehensive analysis of hospital-based prospective cohort reveals the unique effectiveness and safety for nucleos(t)ide analogues in HBV patients. Clinics and research in hepatology and gastroenterology, 2016, Volume: 40, Issue:2 Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Hospitalization; Humans; Lamivudine; Male; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome	2016
Epidemiology study of HBV genotypes and antiviral drug resistance in multi-ethnic regions from Western China. Scientific reports, 2015, Nov-27, Volume: 5 Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Ethnicity; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Epidemiology; Mutation; Organophosphonates; Prevalence	2015
Nephrotoxicity caused by oral antiviral agents in patients with chronic hepatitis B treated in a hospital for tropical diseases in Thailand. BMC pharmacology & toxicology, 2015, Dec-14, Volume: 16 Topics: Adenine; Adult; Antiviral Agents; Creatinine; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Hospitals; Humans; Incidence; Kidney Diseases; Lamivudine; Male; Middle Aged; Nephrons; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Telbivudine; Tenofovir; Thailand; Thymidine; Tropical Medicine	2015
Off-treatment efficacy of 3-year nucleos(t)ide analogues in chronic hepatitis B patients. The Kaohsiung journal of medical sciences, 2016, Volume: 32, Issue:1 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2016
[Drug-resistant mutations in hepatitis B virus found in chronic HBV carriers using PCR sequencing technology]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2016, Volume: 24, Issue:1 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymerase Chain Reaction; Telbivudine; Tenofovir; Thymidine	2016
Profile of HBV polymerase gene mutations during entecavir treatment in patients with chronic hepatitis B. Clinics and research in hepatology and gastroenterology, 2016, Volume: 40, Issue:5 Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Viral Load; Young Adult	2016
Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma. Oncotarget, 2016, May-10, Volume: 7, Issue:19 Topics: Adenine; Administration, Oral; Adolescent; Adult; Amino Acid Sequence; Antiviral Agents; Biopsy; Carcinoma, Hepatocellular; DNA, Circular; Drug Resistance, Viral; Fatty Liver; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Humans; Lamivudine; Liver; Liver Neoplasms; Male; Middle Aged; Necrosis; Organophosphonates; Protein Precursors; Sequence Deletion; Viral Load; Young Adult	2016
De novo entecavir+adefovir dipivoxil+lamivudine triple-resistance mutations resulting from sequential therapy with adefovir dipivoxil, and lamivudine. Annals of clinical microbiology and antimicrobials, 2016, Apr-14, Volume: 15 Topics: Adenine; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Viral Proteins	2016
Hepatitis B virus related cryoglobulinemic vasculitis: A multicentre open label study from the Gruppo Italiano di Studio delle Crioglobulinemie - GISC. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:7 Topics: Adenine; Aged; Antiviral Agents; Cryoglobulinemia; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Italy; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome; Vasculitis	2016
Cost-effectiveness analysis of tenofovir disoproxil fumarate for treatment of chronic hepatitis B in China. Hepatology international, 2016, Volume: 10, Issue:6 Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Markov Chains; Organophosphonates; Quality-Adjusted Life Years; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2016
Impact of FIB-4 index on hepatocellular carcinoma incidence during nucleos(t)ide analogue therapy in patients with chronic hepatitis B: An analysis using time-dependent receiver operating characteristic. Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:2 Topics: Adenine; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Phosphorous Acids; Platelet Count; Proportional Hazards Models; Risk Factors; ROC Curve; Time Factors	2017
The efficacy of tenofovir-based therapy in patients showing suboptimal response to entecavir-adefovir combination therapy. Clinical and molecular hepatology, 2016, Volume: 22, Issue:2 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Republic of Korea; Retrospective Studies; Tenofovir; Treatment Outcome	2016
A five years study of antiviral effect of entecavir in Chinese chronic hepatitis B patients. Scientific reports, 2016, 07-01, Volume: 6 Topics: Adenine; Adult; Antiviral Agents; Asian People; China; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Time Factors; Treatment Outcome; Viral Load	2016
The long-term efficacy of combining nucleos(t)ide analog and low-dose hepatitis B immunoglobulin on post-transplant hepatitis B virus recurrence. Clinical transplantation, 2016, Volume: 30, Issue:10 Topics: Adenine; Administration, Oral; Adult; Aged; Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Immunoglobulins; Immunologic Factors; Kaplan-Meier Estimate; Lamivudine; Liver Transplantation; Male; Middle Aged; Organophosphonates; Postoperative Complications; Proportional Hazards Models; Recurrence; Retrospective Studies; Tenofovir; Treatment Outcome	2016
Nucleos(t)ide analog(s) prophylaxis after hepatitis B immunoglobulin withdrawal against hepatitis B and D recurrence after liver transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5 Topics: Adenine; Adult; Antiviral Agents; Coinfection; DNA, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis D, Chronic; Humans; Immunoglobulins; Lamivudine; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Organophosphonates; Secondary Prevention; Tenofovir; Treatment Outcome; Withholding Treatment; Young Adult	2016
[HBsAg clearance rate in patients with HBeAg-positive chronic hepatitis B: a comparative effect analysis based on the real world]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2016, May-20, Volume: 24, Issue:5 Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome	2016
Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study. Gut and liver, 2017, Jan-15, Volume: 11, Issue:1 Topics: Adenine; Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Cohort Studies; Disease Management; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Viral Load	2017
Comparison of the clinical outcomes between antiviral-naïve patients treated with entecavir and lamivudine-resistant patients receiving adefovir add-on lamivudine combination treatment. Clinical and molecular hepatology, 2016, Volume: 22, Issue:3 Topics: Adenine; Adult; Alanine Transaminase; Antibodies, Viral; Antiviral Agents; Disease Progression; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Treatment Outcome	2016
Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection. Gut, 2018, Volume: 67, Issue:2 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Asymptomatic Infections; Carcinoma, Hepatocellular; Culture Media, Conditioned; DNA, Viral; Female; Gene Expression; Genotype; Guanine; Hep G2 Cells; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HT29 Cells; Humans; Interferons; Interleukins; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Organophosphonates; Polymorphism, Genetic; Recombinant Proteins; Tenofovir; Up-Regulation; Young Adult	2018
Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China. Microbial drug resistance (Larchmont, N.Y.), 2017, Volume: 23, Issue:4 Topics: Adenine; Adult; Antiviral Agents; China; Cohort Studies; Drug Resistance, Multiple, Viral; Female; Gene Expression; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Middle Aged; Mutation Rate; Organophosphonates; Phylogeny; Viral Proteins	2017
DNMT1 modulation in chronic hepatitis B patients and hypothetic influence on mitochondrial DNA methylation status during long-term nucleo(t)side analogs therapy. Journal of medical virology, 2017, Volume: 89, Issue:7 Topics: Adenine; Aged; Antiviral Agents; Cross-Sectional Studies; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA, Mitochondrial; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Nucleosides; Organophosphonates; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine	2017
Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification. Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23 Topics: Antiviral Agents; Cell Line, Tumor; DNA, Viral; Dose-Response Relationship, Drug; Guanine; HEK293 Cells; Herpesvirus 2, Human; HIV; Humans; Leukocytes, Mononuclear; Molecular Structure; Nucleic Acid Amplification Techniques; Organophosphonates; Papillomaviridae; Structure-Activity Relationship; Virus Replication	2016
Comparative evaluation of long-term monotherapies & combination therapies in patients with chronic hepatitis B: A pilot study. The Indian journal of medical research, 2016, Volume: 144, Issue:3 Topics: Adenine; Adult; Drug Combinations; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Pilot Projects; Tenofovir	2016
Evolutionary trends of resistance mutational patterns of HBV reverse transcriptase over years (2002-2012) of different treatment regimens: The legacy of lamivudine/adefovir combination treatment. Antiviral research, 2017, Volume: 143 Topics: Adenine; Antiviral Agents; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Evolution, Molecular; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymorphism, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis; Tenofovir; Treatment Failure	2017
Guanine α-carboxy nucleoside phosphonate (G-α-CNP) shows a different inhibitory kinetic profile against the DNA polymerases of human immunodeficiency virus (HIV) and herpes viruses. Biochemical pharmacology, 2017, 07-15, Volume: 136 Topics: Anti-HIV Agents; Antiviral Agents; DNA-Directed DNA Polymerase; Guanine; Herpesvirus 1, Human; HIV-1; Humans; Kinetics; Nucleosides; Organophosphonates; Protein Structure, Secondary	2017
A different inhibitor is required for overcoming entecavir resistance: a comparison of four rescue therapies in a retrospective study. British journal of clinical pharmacology, 2017, Volume: 83, Issue:10 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Practice Guidelines as Topic; Retrospective Studies; Tenofovir; Treatment Outcome; Viral Load	2017
Lactate serum concentrations during treatment with nucleos(t)ide analogues in hepatitis B with or without cirrhosis. European journal of gastroenterology & hepatology, 2017, Volume: 29, Issue:9 Topics: Acidosis, Lactic; Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lactic Acid; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Prospective Studies; Risk Factors; Sex Factors; Tenofovir; Time Factors; Treatment Outcome; Up-Regulation; Young Adult	2017
Comparing Efficacy of Lamivudine, Adefovir Dipivoxil, Telbivudine, and Entecavir in Treating Nucleoside Analogues Naïve for HBeAg-Negative Hepatitis B with Medium Hepatitis B Virus (HBV) DNA Levels. Medical science monitor : international medical journal of experimental and clinical research, 2017, Nov-02, Volume: 23 Topics: Adenine; Adult; Alanine Transaminase; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B e Antigens; Humans; Lamivudine; Male; Multivariate Analysis; Nucleosides; Organophosphonates; Proportional Hazards Models; Telbivudine; Thymidine	2017
Direct Detection of Drug-Resistant Hepatitis B Virus in Serum Using a Dendron-Modified Microarray. Gut and liver, 2018, May-15, Volume: 12, Issue:3 Topics: Adenine; Dendrimers; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microarray Analysis; Mutation; Nucleic Acid Amplification Techniques; Organophosphonates; Reverse Transcriptase Polymerase Chain Reaction	2018
Evaluation of ODE-Bn-PMEG, an acyclic nucleoside phosphonate prodrug, as an antiviral against productive HPV infection in 3D organotypic epithelial cultures. Antiviral research, 2018, Volume: 150 Topics: Animals; Antiviral Agents; DNA Damage; DNA Replication; DNA, Viral; Drug Evaluation, Preclinical; Guanine; Humans; Organophosphonates; Papillomaviridae; Prodrugs; Virus Replication	2018
Hepatitis B virus rtA181T/sW172non-stop mutation may increase resistance fold to adefovir- and entecavir-resistant mutants compared to rtA181T/sW172* mutation. Antiviral research, 2018, Volume: 154 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; RNA-Directed DNA Polymerase	2018
Trends in hepatitis B virus resistance to nucleoside/nucleotide analogues in North China from 2009-2016: A retrospective study. International journal of antimicrobial agents, 2018, Volume: 52, Issue:2 Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; China; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Virus Activation; Virus Replication	2018
Combination therapy for chronic hepatitis B: The future and beyond. Journal of the Formosan Medical Association = Taiwan yi zhi, 2018, Volume: 117, Issue:8 Topics: Adenine; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Recombinant Proteins	2018
Synthesis of Cyclic Megamolecules. Journal of the American Chemical Society, 2018, 05-23, Volume: 140, Issue:20 Topics: Carboxylic Ester Hydrolases; Cross-Linking Reagents; Cyclization; Guanine; Macrocyclic Compounds; Models, Molecular; Nitrophenols; O(6)-Methylguanine-DNA Methyltransferase; Organophosphonates; Protein Domains; Protein Multimerization	2018
48-Week Outcome after Cessation of Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patient and the Associated Factors with Relapse. Canadian journal of gastroenterology & hepatology, 2018, Volume: 2018 Topics: Adenine; Adult; Antiviral Agents; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Nucleosides; Organophosphonates; Outpatients; Prognosis; Prospective Studies; Recurrence; Risk Factors; RNA, Viral; Telbivudine; Time Factors; Treatment Outcome; Withholding Treatment	2018
Long-term results of chronic hepatitis B antiviral treatment with nucleos(t)ide analogues: a single center experience. Minerva gastroenterologica e dietologica, 2019, Volume: 65, Issue:1 Topics: Adenine; Adult; Aged; Aged, 80 and over; Antiviral Agents; Drug Therapy, Combination; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Young Adult	2019
Synthesis of Guanine α-Carboxy Nucleoside Phosphonate (G-α-CNP), a Direct Inhibitor of Multiple Viral DNA Polymerases. The Journal of organic chemistry, 2018, 09-07, Volume: 83, Issue:17 Topics: Catalysis; Chemistry Techniques, Synthetic; DNA-Directed DNA Polymerase; Guanine; HIV-1; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Palladium; Purine Nucleosides	2018
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus. Antiviral research, 2018, Volume: 158 Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication	2018
[A Case of Fanconi's Syndrome Induced by Adefovir in Hepatitis Type B Patient]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2016, Volume: 105, Issue:6 Topics: Adenine; Aged; Antiviral Agents; Fanconi Syndrome; Female; Guanine; Hepatitis B, Chronic; Humans; Organophosphonates	2016
Management of individuals with chronic hepatitis B virus infection and persistent normal or mildly elevated aminotransferase levels. Journal of cellular biochemistry, 2019, Volume: 120, Issue:4 Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Biopsy; Disease Management; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Organophosphonates; Retrospective Studies	2019
Very late onset post-transplant diffuse large B cell lymphoma in a liver transplant recipient with hepatitis B: A case report. Medicine, 2018, Volume: 97, Issue:44 Topics: Adenine; Antiviral Agents; Biopsy, Fine-Needle; Chemoradiotherapy; Guanine; Hepatitis B; Hepatitis B virus; Humans; Immunosuppressive Agents; Liver Transplantation; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Organophosphonates; Tomography, X-Ray Computed; Treatment Outcome; Virus Replication	2018
Synthesis and Anti-HIV Activity of Guanine Modified Fluorinated Acyclic Nucleoside Phosphonate Derivatives. Chemistry & biodiversity, 2019, Volume: 16, Issue:2 Topics: Anti-HIV Agents; Guanine; Halogenation; HIV-1; Humans; Nucleosides; Organophosphonates	2019
Performance of serum HBcrAg in chronic hepatitis B patients with 8-year nucleos(t)ide analogs therapy. Clinics and research in hepatology and gastroenterology, 2019, Volume: 43, Issue:3 Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Retrospective Studies; Seroconversion	2019
Methylation status of the stimulator of interferon genes promoter in patients with chronic hepatitis B. Medicine, 2018, Volume: 97, Issue:52 Topics: Adenine; Adult; Antiviral Agents; Biomarkers; DNA, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Leukocytes, Mononuclear; Male; Methylation; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Sustained Virologic Response	2018
Entecavir and Low Genetic Barrier Antiviral Agents for Hepatocellular Carcinoma in Hepatitis B Viral Cirrhosis: Propensity Score Matching. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:4 Topics: Adenine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; China; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Incidence; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Organophosphonates; Retrospective Studies; Risk Factors; Telbivudine	2019
Long-term Nucleotide Analogue Treatment Has Higher Levels of Renal Toxicities than Does Entecavir in Patients with Chronic Hepatitis B. Gut and liver, 2020, 03-15, Volume: 14, Issue:2 Topics: Adenine; Adult; Aged; Antiviral Agents; Chemical and Drug Induced Liver Injury; Female; Glomerular Filtration Rate; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Male; Middle Aged; Nucleotides; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Tenofovir; Time Factors; Treatment Outcome	2020
Long-term prognosis of liver disease in patients with chronic hepatitis B virus infection receiving nucleos(t)ide analogue therapy: an analysis using a Markov chain model. European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:11 Topics: Adenine; Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Markov Chains; Middle Aged; Nucleosides; Organophosphonates; Prognosis	2019
Immunomodulatory Mechanism of Acyclic Nucleoside Phosphates in Treatment of Hepatitis B Virus Infection. Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:5 Topics: Adenine; Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunomodulation; Interferon-alpha; Interleukin-10; Interleukin-12; Lamivudine; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Nucleosides; Organophosphonates; Proto-Oncogene Proteins c-akt; Tenofovir	2020
Effect of nucleos(t)ide analogue on serum HBsAg level in chronic hepatitis B patients: A 3-years study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 122 Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Nucleotidases; Organophosphonates; Viral Load	2020
Pregnancy outcomes for pregnant women with chronic hepatitis B exposing to entecavir or adefovir dipivoxil therapy before or in early pregnancy. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022, Volume: 35, Issue:3 Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Organophosphonates; Pregnancy; Pregnancy Outcome; Pregnant Women; Retrospective Studies; Treatment Outcome; Viral Load	2022
Hepatitis B virus mutation pattern rtA181S+T184I+M204I may contribute to multidrug resistance in clinical practice: Analysis of a large cohort of Chinese patients. Antiviral research, 2020, Volume: 180 Topics: Adenine; Adult; Antiviral Agents; Asian People; Beijing; Cohort Studies; DNA, Viral; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Longitudinal Studies; Male; Middle Aged; Mutation; Organophosphonates; Prevalence	2020
Is tenofovir and entecavir combination therapy still the optimal treatment for chronic hepatitis B patients with prior suboptimal response? Clinical and molecular hepatology, 2020, Volume: 26, Issue:3 Topics: Adenine; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Telbivudine; Tenofovir	2020
Multiple drug-resistant HBV mutation may contribute to poor response of adefovir + entecavir in entecavir-resistant patients. Journal of infection in developing countries, 2021, 01-31, Volume: 15, Issue:1 Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; RNA-Directed DNA Polymerase; Tenofovir; Viral Load; Virus Replication	2021
Another oral antiviral treatment, but still far away from hepatitis B virus cure. Clinical and molecular hepatology, 2021, Volume: 27, Issue:2 Topics: Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Maleates; Organophosphonates; Tenofovir	2021
Investigation of multidrug-resistance mutations of hepatitis B virus (HBV) in a large cohort of chronic HBV-infected patients with treatment of nucleoside/nucleotide analogs. Antiviral research, 2021, Volume: 189 Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Multiple, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Mutation; Nucleosides; Nucleotides; Organophosphonates; Phylogeny; Telbivudine; Viral Load; Virus Replication	2021
Besifovir dipivoxil maleate: a novel antiviral agent with low toxicity and high genetic barriers for chronic hepatitis B. Expert opinion on pharmacotherapy, 2021, Volume: 22, Issue:18 Topics: Animals; Antiviral Agents; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Maleates; Organophosphonates	2021
Besifovir therapy improves hepatic histology and reduces covalently closed circular DNA in chronic hepatitis B patients. Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:2 Topics: Antiviral Agents; DNA, Circular; Guanine; Hepatitis B, Chronic; Humans; Liver; Organophosphonates; Treatment Outcome	2022
Similar risk of kidney function decline between tenofovir alafenamide and besifovir dipivoxil maleate in chronic hepatitis B. Liver international : official journal of the International Association for the Study of the Liver, 2022, Volume: 42, Issue:11 Topics: Adenine; Alanine; Antiviral Agents; Guanine; Hepatitis B; Hepatitis B, Chronic; Humans; Kidney; Longitudinal Studies; Maleates; Organophosphonates; Renal Insufficiency, Chronic; Retrospective Studies; Tenofovir; Treatment Outcome	2022