organophosphonates has been researched along with fluorouracil in 12 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (fluorouracil) | Trials (fluorouracil) | Recent Studies (post-2010) (fluorouracil) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 45,562 | 9,307 | 14,663 |
| Protein | Taxonomy | organophosphonates (IC50) | fluorouracil (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 0.32 | |
| Thymidylate synthase | Mus musculus (house mouse) | 1.58 | |
| Aromatase | Homo sapiens (human) | 0.63 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Berkowitz, I; Berry, D; Costanza, ME; Duggan, D; Henderson, IC; Kalra, J; Lyss, AP; Ratain, MJ; Shapiro, C; Wu, K | 1 |
| Berry, DA; Cirrincione, C; Costanza, ME; Frei, E; Henderson, IC; McIntyre, OR; Norton, L; Schilsky, RL; Weiss, RB; Winer, E; Wood, WC | 1 |
| Innocenti, F; Iyer, L; Ratain, MJ | 1 |
| Moore, MJ | 1 |
| Belinsky, MG; Chen, ZS; Guo, Y; Hopper-Borge, E; Kotova, E; Kruh, GD; Lee, K | 1 |
| Bernard, HU | 1 |
| Chang, HJ; Hong, SH; Jeon, E; Park, JG; Shin, YK; Yoo, BC | 1 |
| Höltje, HD; Höltje, M; Korting, HC; Murruzzu, C; Natek, M; Reissig, HU; Schäfer-Korting, M; Schwanke, A; Zdrazil, B; Zuhse, R | 1 |
| Fox, PA | 1 |
| Makino, K; Shimamura, Y; Takeuchi, I; Terada, H | 1 |
| Makino, K; Takeuchi, I; Tanaka, K | 1 |
| Ali, OM; Alotaibi, MT; Amer, HH; Zaki, YH | 1 |
4 review(s) available for organophosphonates and fluorouracil
| Article | Year |
|---|---|
Pharmacogenetics: a tool for individualizing antineoplastic therapy.
Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype | 2000 |
Pancreatic cancer: what the oncologist can offer for palliation.
Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Deoxycytidine; Enzyme Inhibitors; Fluorouracil; Gemcitabine; Genes, ras; Humans; Mutation; Neoplasm Recurrence, Local; Organophosphonates; Palliative Care; Pancreatic Neoplasms | 2002 |
Established and potential strategies against papillomavirus infections.
Topics: Aminoquinolines; Antimetabolites; Antiviral Agents; Cidofovir; Cytosine; Drug Design; Fluorouracil; Humans; Imiquimod; Indoles; Interferon Inducers; Interferons; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Podophyllin; Viral Vaccines | 2004 |
Treatment options for anal intraepithelial neoplasia and evidence for their effectiveness.
Topics: Adult; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Anus Neoplasms; Cidofovir; Comorbidity; Cytosine; Female; Fluorouracil; Global Health; HIV Infections; Homosexuality, Male; Humans; Imiquimod; Incidence; Male; Organophosphonates; Papillomavirus Infections; Precancerous Conditions; Trichloroacetic Acid | 2012 |
2 trial(s) available for organophosphonates and fluorouracil
| Article | Year |
|---|---|
Amonafide: An active agent in the treatment of previously untreated advanced breast cancer--a cancer and leukemia group B study (CALGB 8642).
Topics: Adenine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Imides; Isoquinolines; Menopause; Middle Aged; Naphthalimides; Neoplasm Metastasis; Organophosphonates; Receptors, Estrogen | 1995 |
Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642.
Topics: Adenine; Adult; Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Imides; Isoquinolines; Melphalan; Middle Aged; Naphthalimides; Neoplasm Staging; Organophosphonates; Prospective Studies; Survival Analysis; Trimetrexate | 1999 |
6 other study(ies) available for organophosphonates and fluorouracil
| Article | Year |
|---|---|
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.
Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cell Membrane; Colforsin; Coloring Agents; Cyclic AMP; Cyclic GMP; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Floxuridine; Fluorouracil; Genetic Vectors; Growth Inhibitors; Immunoblotting; Inhibitory Concentration 50; Insecta; Models, Biological; Nitrosamines; Nucleotides; Organophosphonates; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Zalcitabine | 2003 |
Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line.
Topics: Amino Acids; Aminobutyrates; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Excitatory Amino Acid Agonists; Fluorouracil; Humans; Ligands; Organophosphonates; Receptors, Metabotropic Glutamate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Antitumor effects of guanosine-analog phosphonates identified by molecular modelling.
Topics: Adenine; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Fluorouracil; HT29 Cells; Humans; Keratinocytes; Keratosis, Actinic; Models, Molecular; Molecular Dynamics Simulation; Organophosphonates | 2010 |
Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.
Topics: Aminobutyrates; Animals; Disease Models, Animal; Fluorouracil; gamma-Glutamyltransferase; Humans; Mice; Neoplasms; Organophosphonates; Reactive Oxygen Species; Stomatitis | 2019 |
Therapeutic Effects of GGsTop
Topics: Aminobutyrates; Animals; Antimetabolites, Antineoplastic; Body Weight; Collagen; Disease Models, Animal; Drug Dosage Calculations; Fluorouracil; Gels; Glutathione; Leukocytes; Male; Mice; Organophosphonates; Stomatitis | 2021 |
Design, Synthesis, and Spectroscopic Studies of Some New α-Aminophosphonate Analogues Derived from 4-Hydroxybenzaldehyde with Special Reference to Anticancer Activity.
Topics: Benzaldehydes; Fluorouracil; Humans; Leukocytes, Mononuclear; Molecular Docking Simulation; Organophosphonates; Structure-Activity Relationship | 2022 |