Page last updated: 2024-09-05

organophosphonates and estrone

organophosphonates has been researched along with estrone in 3 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(estrone)
Trials
(estrone)
Recent Studies (post-2010) (estrone)
9,9688803,59610,2664321,372

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)estrone (IC50)
Estrogen receptorHomo sapiens (human)0.1261
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.589
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.4134
Sodium-dependent serotonin transporterHomo sapiens (human)5.301
Estrogen receptor betaHomo sapiens (human)0.3743
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Benezra, C; Bravet, JL; Weniger, JP1
Howarth, NM; Potter, BV; Purohit, A; Reed, MJ; Robinson, JJ; Vicker, N1
Jójárt, R; Kecskeméti, G; Klement, M; Kőhl, G; Laczkó-Rigó, R; Mernyák, E; Özvegy-Laczka, C1

Other Studies

3 other study(ies) available for organophosphonates and estrone

ArticleYear
Steroyl phosphonates. 3. Dimethyl phosphonates in the estrone series.
    Steroids, 1972, Volume: 19, Issue:1

    Topics: Androstanes; Animals; Chick Embryo; Circular Dichroism; Estrone; Female; Infrared Rays; Ketones; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Methanol; Optical Rotation; Optical Rotatory Dispersion; Organophosphonates; Sex Determination Analysis; Spectrum Analysis; Stereoisomerism; Structure-Activity Relationship; Ultraviolet Rays

1972
Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies.
    Biochemistry, 2002, Dec-17, Volume: 41, Issue:50

    Topics: Animals; Binding Sites; Breast Neoplasms; Crotalid Venoms; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estrone; Humans; Models, Chemical; Models, Molecular; Molecular Mimicry; Organophosphonates; Sequence Homology, Amino Acid; Stereoisomerism; Structure-Activity Relationship; Sulfatases; Tetrahydronaphthalenes; Tumor Cells, Cultured

2002
Design, synthesis and biological evaluation of novel estrone phosphonates as high affinity organic anion-transporting polypeptide 2B1 (OATP2B1) inhibitors.
    Bioorganic chemistry, 2021, Volume: 112

    Topics: Dose-Response Relationship, Drug; Drug Design; Estrone; Humans; Molecular Structure; Organic Anion Transporters; Organophosphonates; Structure-Activity Relationship

2021