Page last updated: 2024-09-05

organophosphonates and chaetomellic acid a

organophosphonates has been researched along with chaetomellic acid a in 2 studies

Compound Research Comparison

Studies (organophosphonates)	Trials (organophosphonates)	Recent Studies (post-2010) (organophosphonates)	Studies (chaetomellic acid a)	Trials (chaetomellic acid a)	Recent Studies (post-2010) (chaetomellic acid a)
9,968	880	3,596	21	0	7

Protein Interaction Comparison

Protein	Taxonomy	organophosphonates (IC50)	chaetomellic acid a (IC50)
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	Homo sapiens (human)		0.13
Protein farnesyltransferase subunit beta	Homo sapiens (human)		0.13

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gibbs, JB; Kohl, NE; Lingham, RB; Mosser, SD; Oliff, A; Pompliano, DL; Rands, E; Scolnick, EM; Singh, SB	1
Cornish, K; Garneau, S; Mau, CJ; Scholte, AA; Van Fleet, JE; Vederas, JC	1

Other Studies

2 other study(ies) available for organophosphonates and chaetomellic acid a

Article	Year
Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11 Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Line, Transformed; Farnesol; Gene Expression Regulation; Genes, ras; Kinetics; Maleates; Mice; Organophosphonates; Organophosphorus Compounds; Protein Processing, Post-Translational; Transferases; Tricarboxylic Acids	1993
Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. European journal of biochemistry, 2003, Volume: 270, Issue:19 Topics: Alkyl and Aryl Transferases; Asteraceae; Binding Sites; Dimethylallyltranstransferase; Enzyme Inhibitors; Farnesol; Farnesyltranstransferase; Glutarates; Hevea; Kinetics; Lithium Compounds; Maleates; Organophosphonates; Polyisoprenyl Phosphates; Salts; Sesquiterpenes; Solvents; Species Specificity	2003

Article

Year

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11

Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Line, Transformed; Farnesol; Gene Expression Regulation; Genes, ras; Kinetics; Maleates; Mice; Organophosphonates; Organophosphorus Compounds; Protein Processing, Post-Translational; Transferases; Tricarboxylic Acids

1993

Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase.

European journal of biochemistry, 2003, Volume: 270, Issue:19

Topics: Alkyl and Aryl Transferases; Asteraceae; Binding Sites; Dimethylallyltranstransferase; Enzyme Inhibitors; Farnesol; Farnesyltranstransferase; Glutarates; Hevea; Kinetics; Lithium Compounds; Maleates; Organophosphonates; Polyisoprenyl Phosphates; Salts; Sesquiterpenes; Solvents; Species Specificity

2003