organophosphonates has been researched along with arachidonic acid in 43 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (arachidonic acid) | Trials (arachidonic acid) | Recent Studies (post-2010) (arachidonic acid) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 19,295 | 486 | 3,040 |
| Protein | Taxonomy | organophosphonates (IC50) | arachidonic acid (IC50) |
|---|---|---|---|
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | 2.75 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
| 60 kDa chaperonin | Escherichia coli | 7.3 | |
| 10 kDa chaperonin | Escherichia coli | 7.3 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.0715 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.6026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (25.58) | 18.2507 |
| 2000's | 30 (69.77) | 29.6817 |
| 2010's | 2 (4.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lefkowith, JB; Rogers, M; Teslenko, V | 1 |
| Burke, JR; Davern, LB; Gregor, KR; Tramposch, KM | 1 |
| Goparaju, SK; Ueda, N; Yamaguchi, H; Yamamoto, S | 1 |
| Basavarajappa, BS; Cooper, TB; Hungund, BL | 1 |
| Balboa, MA; Balsinde, J; Dennis, EA | 1 |
| Brekke, OL; Espevik, T; Gåsvik, K; Hanssen, W; Holmeide, AK; Johansen, B; Laegreid, A; Sjursen, W; Skattebøl, L; Thommesen, L | 1 |
| Goparaju, SK; Katayama, K; Kurahashi, Y; Suzuki, H; Ueda, N; Yamamoto, S | 1 |
| Ginalis, E; Greco, R; Haimovich, B; Ji, P; Kramer, R | 1 |
| Akiba, S; Hayama, M; Kume, K; Mizunaga, S; Sato, T | 1 |
| Fest, W; Huttner, WB; Kratzin, H; Podtelejnikov, AV; Schmidt, A; Söling, HD; Thiele, C; Witke, W; Wolde, M | 1 |
| Eker, P; Garred, O; Llorente, A; Sandvig, K; van Deurs, B | 1 |
| Akiba, S; Hashizume, T; Hayama, M; Kageura, T; Kitatani, K; Sato, T | 1 |
| Dominguez, Z; Dubois, M; Lagarde, M; Macovschi, O; Merhi-Soussi, F; Prigent, AF; Savany, A | 1 |
| Levine, L | 1 |
| Allred, DV; Bell, JD; O'Neill, K; Wilson, HA | 1 |
| Fujita, S; Ikegaya, Y; Matsuki, N; Nishikawa, M; Nishiyama, N | 1 |
| Boilard, E; Surette, ME | 1 |
| Linch, DC; Mollapour, E; Roberts, PJ | 1 |
| Derr-Yellin, EC; Kodavanti, PR | 1 |
| Cowan, MJ; Gladwin, MT; Huang, XL; Logun, C; Madara, P; Pawliczak, R; Shelhamer, JH | 1 |
| Kudo, I; Masuda, S; Murakami, M | 1 |
| Davies, JE; Jennings, SC; Ng, LL; Pettit, AI; Quinn, PA; Wong, RK | 1 |
| Balboa, MA; Balsinde, J; Dennis, EA; Ellisman, MH; Gaietta, G; Shirai, Y | 1 |
| Anthonsen, MW; Johansen, B; Oestvang, J | 1 |
| Han, C; Shelhamer, JH; Wu, T | 1 |
| Balboa, MA; Balsinde, J; Melero, R; Pérez, R | 1 |
| Akiba, S; Ii, H; Sato, T; Yoneda, Y | 1 |
| Aliza, AR; Park, Y; Stanley, D | 1 |
| Dennis, EA; Lucas, KK; Winstead, MV | 1 |
| Albano, RM; Assis, MC; Bozza, PT; Coelho, MG; Gayer, CR; Lopes, UG; Marques, EA; Nascimento, DO; Paiva, DD; Plotkowski, MC; Raymond, B; Saliba, AM; Silva, MC; Touqui, L | 1 |
| Balboa, MA; Balsinde, J; Casas, J; Crespo, MS; Gijón, MA; Vigo, AG | 1 |
| Chechneva, O; Reiser, G; Reymann, KG; Strokin, M | 1 |
| Guo, Y; Liu, L; Lou, L; Xie, Y; Yu, Z | 1 |
| Haneji, T; Nagata, T; Shinohara, H; Yoshida, K | 1 |
| Beckett, CS; McHowat, J; Rastogi, P | 1 |
| Slomiany, A; Slomiany, BL | 1 |
| Dong, B; Matsumura, F | 1 |
| Bozza, PT; Brandão, BA; de Assis, MC; Feliciano, LF; Freitas, C; Plotkowski, MC; Raymond, B; Saliba, AM; Touqui, L; Zahm, JM | 1 |
| Chen, LY; Logun, C; Nagineni, S; Shelhamer, JH; Woszczek, G | 1 |
| Cummings, BS; Franklin, JL; Monian, P; Peterson, B; Stovall, K | 1 |
| Balasubramanian, KA; Basivireddy, J; Jacob, M; Pulimood, AB; Sivalingam, N | 1 |
| Drevenšek, G; Ljuca, F; Zerem, E | 1 |
| Chen, X; Guo, M; Han, Q; Lai, J; Lu, M; Pei, R; Wang, Y; Wu, C; Xu, S; Zhou, Y | 1 |
1 review(s) available for organophosphonates and arachidonic acid
| Article | Year |
|---|---|
A hydrolase enzyme inactivating endogenous ligands for cannabinoid receptors.
Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; COS Cells; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Esterases; Ethanolamine; Fatty Acids; Hydrolysis; Intestine, Small; Ligands; Liver; Nerve Tissue Proteins; Organ Specificity; Organophosphonates; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Recombinant Fusion Proteins; Swine | 1998 |
42 other study(ies) available for organophosphonates and arachidonic acid
| Article | Year |
|---|---|
Macrophage arachidonate release via both the cytosolic Ca(2+)-dependent and -independent phospholipases is necessary for cell spreading.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Adhesion; Cell Movement; Cytosol; Enzyme Activation; Enzyme Inhibitors; Kinetics; Macrophages, Peritoneal; Mice; Organophosphonates; Phenotype; Phospholipases A; Phospholipases A2; Protein Kinase C | 1997 |
Leukotriene B4 stimulates the release of arachidonate in human neutrophils via the action of cytosolic phospholipase A2.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cytosol; Enzyme Inhibitors; Humans; Leukotriene B4; Neutrophils; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipids; Thimerosal | 1997 |
Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand.
Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; CHO Cells; Cricetinae; Diglycerides; Endocannabinoids; Enzyme Inhibitors; Gene Expression; Glycerides; Hydrogen-Ion Concentration; Kinetics; Liver; Organophosphonates; Phenylmethylsulfonyl Fluoride; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Transfection | 1998 |
Effect of chronic ethanol exposure on mouse brain arachidonic acid specific phospholipase A2.
Topics: Alcoholism; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Calcium; Dithiothreitol; Enzyme Inhibitors; Ethanol; Glycerol; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Mice; Organophosphonates; Phospholipases A; Phospholipases A2; Subcellular Fractions; Substrate Specificity; Sulfhydryl Reagents; Synaptic Membranes | 1998 |
Involvement of phosphatidate phosphohydrolase in arachidonic acid mobilization in human amnionic WISH cells.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Organophosphonates; Phosphatidate Phosphatase; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Tetradecanoylphorbol Acetate | 1998 |
Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cytosol; Eicosapentaenoic Acid; Enzyme Inhibitors; Genetic Vectors; Homosteroids; Humans; Insecta; Intercellular Adhesion Molecule-1; Interleukin-1; Keratinocytes; NF-kappa B; Organophosphonates; Phospholipases A; Phospholipases A2; Recombinant Proteins; Sesterterpenes; Terpenes; Tumor Necrosis Factor-alpha; Up-Regulation | 1998 |
Phospholipase A2 enzymes regulate alpha IIb beta3-mediated, but not Fc gammaRII receptor-mediated, pp125FAK phosphorylation in platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Adhesion; Cell Adhesion Molecules; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoglobulin G; Naphthalenes; Organophosphonates; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein-Tyrosine Kinases; Pyrones; Receptors, IgG | 1999 |
Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Diglycerides; Egtazic Acid; Group VI Phospholipases A2; Indoles; Leukemia P388; Maleimides; Mice; Naphthalenes; Oligonucleotides, Antisense; Organophosphonates; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrones; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan | 1999 |
Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.
Topics: Acyl Coenzyme A; Acyltransferases; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Arachidonic Acid; Arachidonic Acids; Carrier Proteins; Cattle; Cell Membrane; Enzyme Inhibitors; Humans; Lysophospholipids; Membrane Fusion; Membrane Lipids; Mice; Models, Biological; Molecular Conformation; Molecular Sequence Data; Organophosphonates; PC12 Cells; Phospholipases A; Phosphorylation; Protein Binding; Rats; Recombinant Fusion Proteins; src Homology Domains; Synaptic Vesicles | 1999 |
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Cell Polarity; Cyclic AMP-Dependent Protein Kinases; Cyclohexanones; Cyclooxygenase Inhibitors; Dogs; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Heterotrimeric GTP-Binding Proteins; Intercellular Signaling Peptides and Proteins; Ionomycin; Lipoprotein Lipase; Lipoxygenase Inhibitors; Organophosphonates; Peptides; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Ricin; Signal Transduction; Tetradecanoylphorbol Acetate; Wasp Venoms | 2000 |
Ceramide enhances susceptibility of membrane phospholipids to phospholipase A2 through modification of lipid organization in platelet membranes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane; Ceramides; Cytosol; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Lysophosphatidylcholines; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipids; Rabbits; Signal Transduction; Thromboxane A2 | 1999 |
Human lymphocytes stimulate prostacyclin synthesis in human umbilical vein endothelial cells. Involvement of endothelial cPLA2.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis; Calcium; Cell Adhesion; Cells, Cultured; Chelating Agents; Coculture Techniques; Culture Media, Conditioned; Cyclooxygenase 1; Cyclooxygenase 2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Gene Expression Regulation; Group IV Phospholipases A2; Humans; Infant, Newborn; Intramolecular Oxidoreductases; Isoenzymes; Lipopolysaccharides; Lymphocytes; Membrane Proteins; Organophosphonates; Phospholipases A; Phospholipases A2; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Tranylcypromine; Umbilical Veins | 2000 |
A combination of lactacystin and 12-O-tetradecanoylphorbol-13-acetate enhances the release of arachidonic acid from cells in cultures: release is reduced in confluent and serum deprived cells.
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Cattle; Cell Division; Cells, Cultured; Contact Inhibition; Culture Media; Culture Media, Serum-Free; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dexamethasone; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Gliotoxin; Group IV Phospholipases A2; Hepatocytes; Immunosuppressive Agents; Multienzyme Complexes; Muscle, Smooth, Vascular; Neuroglia; Organophosphonates; Phospholipases A; Phospholipases A2; Proteasome Endopeptidase Complex; Pulmonary Artery; Rats; Sodium Salicylate; Tetradecanoylphorbol Acetate | 2000 |
Activities and interactions among phospholipases A2 during thapsigargin-induced S49 cell death.
Topics: Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Cell Membrane; DNA Fragmentation; Enzyme Inhibitors; Lymphoma; Mice; Organophosphonates; Phospholipases A; Phospholipases A2; Thapsigargin; Tritium; Tumor Cells, Cultured | 2000 |
Docosahexaenoic acid improves long-term potentiation attenuated by phospholipase A(2) inhibitor in rat hippocampal slices.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Naphthalenes; Organophosphonates; Phosphodiesterase Inhibitors; Phospholipases A; Pyrones; Rats; Rats, Wistar; Time Factors | 2001 |
Anti-CD3 and concanavalin A-induced human T cell proliferation is associated with an increased rate of arachidonate-phospholipid remodeling. Lack of involvement of group IV and group VI phospholipase A2 in remodeling and increased susceptibility of prolif
Topics: Acyltransferases; Apoptosis; Arachidonic Acid; Arachidonic Acids; CD3 Complex; Cell Division; Cells, Cultured; Concanavalin A; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-2; Kinetics; Lymphocyte Activation; Muromonab-CD3; Naphthalenes; Oleic Acid; Organophosphonates; Organophosphorus Compounds; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phospholipids; Pyrones; T-Lymphocytes; Thymidine | 2001 |
Activation and priming of neutrophil nicotinamide adenine dinucleotide phosphate oxidase and phospholipase A(2) are dissociated by inhibitors of the kinases p42(ERK2) and p38(SAPK) and by methyl arachidonyl fluorophosphonate, the dual inhibitor of cytosol
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Complement C5a; Cytosol; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; Group VI Phospholipases A2; Humans; Imidazoles; Ionophores; Isoenzymes; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Organophosphonates; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Protein Serine-Threonine Kinases; Pyridines; Respiratory Burst; Superoxides; Tumor Necrosis Factor-alpha | 2001 |
Differential effects of polybrominated diphenyl ethers and polychlorinated biphenyls on [3H]arachidonic acid release in rat cerebellar granule neurons.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Flame Retardants; Halogenated Diphenyl Ethers; Hydrocarbons, Brominated; Neurons; Organophosphonates; Phenyl Ethers; Phospholipases A; Polybrominated Biphenyls; Polychlorinated Biphenyls; Rats; Rats, Long-Evans; Time Factors; Tritium | 2002 |
Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells.
Topics: Annexin A2; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Calcium-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; HeLa Cells; Humans; Ionophores; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Organophosphonates; Phospholipases A; Phosphorylation; Recombinant Proteins; S100 Proteins | 2002 |
Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma).
Topics: Amino Acid Substitution; Animals; Arachidonic Acid; Arachidonic Acids; Binding Sites; Blotting, Northern; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cytosol; DNA, Complementary; Endoplasmic Reticulum; Humans; Isoenzymes; Membrane Proteins; Mice; Microscopy, Confocal; Nitrobenzenes; Organophosphonates; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfonamides; Transfection | 2003 |
Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic Acid.
Topics: Acetylcysteine; Adult; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Enzyme Inhibitors; Glycation End Products, Advanced; Group IV Phospholipases A2; Humans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organophosphonates; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Quinacrine; Reactive Oxygen Species; Respiratory Burst; Vascular Diseases | 2003 |
Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caveolin 1; Caveolin 2; Caveolins; Cell Line; Cell Membrane; Cell Nucleus; Cyclooxygenase 2; DNA, Complementary; Enzyme Inhibitors; Fibroblasts; Green Fluorescent Proteins; Heparin; Isoenzymes; Lipopolysaccharides; Luminescent Proteins; Macrophages; Mice; Microscopy, Fluorescence; Models, Biological; Organophosphonates; Peptides; Phospholipases A; Phospholipases A2; Plasmids; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Binding; Time Factors; Transfection | 2003 |
Role of secretory and cytosolic phospholipase A(2) enzymes in lysophosphatidylcholine-stimulated monocyte arachidonic acid release.
Topics: Arachidonic Acid; Arachidonic Acids; Carbon Radioisotopes; Cell Differentiation; Cell Line; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lysophosphatidylcholines; Monocytes; Oleic Acid; Organophosphonates; Pertussis Toxin; Phospholipases A; Phospholipases A2; Time Factors; Tritium | 2003 |
Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bronchi; Cells, Cultured; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Imidazoles; Interferon-gamma; Interleukin-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Organophosphonates; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Kinase C; Pyridines; Pyrones | 2004 |
Role of group VIA calcium-independent phospholipase A2 in arachidonic acid release, phospholipid fatty acid incorporation, and apoptosis in U937 cells responding to hydrogen peroxide.
Topics: Apoptosis; Arachidonic Acid; Arachidonic Acids; Fatty Acids; Fluorescein-5-isothiocyanate; Group VI Phospholipases A2; Humans; Hydrogen Peroxide; Hydrolysis; Lactones; Oligonucleotides, Antisense; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipids; Thimerosal; Time Factors; Transfection; U937 Cells | 2004 |
Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Membrane; Cells, Cultured; Cholesterol; Cholesterol Esters; Cytosol; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Ionophores; Linoleic Acids; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Organophosphonates; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Protein Transport | 2004 |
A secretory PLA2 associated with tobacco hornworm hemocyte membrane preparations acts in cellular immune reactions.
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbon Radioisotopes; Cell Membrane; Cytosol; Dexamethasone; Fatty Acids, Unsaturated; Hemocytes; Immunity, Cellular; Lipopolysaccharides; Manduca; Organophosphonates; Phospholipases A; Phospholipases A2; Scintillation Counting; Xenorhabdus | 2005 |
Group IV cytosolic phospholipase A2 mediates arachidonic acid release in H9c2 rat cardiomyocyte cells in response to hydrogen peroxide.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Base Sequence; Cell Line; Cytosol; DNA Primers; Heart; Hydrogen Peroxide; Myocardium; Organophosphonates; Phospholipases A; Phospholipases A2; Rats; RNA, Messenger | 2005 |
Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Bacterial Toxins; Cell Line; Dinoprostone; Eicosanoids; Endothelial Cells; Epoprostenol; Female; Group IV Phospholipases A2; Humans; Ibuprofen; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred BALB C; Organophosphonates; Phospholipases A; Pseudomonas aeruginosa; Pseudomonas Infections | 2005 |
Overexpression of cytosolic group IVA phospholipase A2 protects cells from Ca2+-dependent death.
Topics: Animals; Annexin A5; Arachidonic Acid; Arachidonic Acids; Calcium; Carbocyanines; Cell Death; Cell Line; Enzyme Inhibitors; Fluorescent Dyes; Group IV Phospholipases A2; Humans; Ionomycin; Ionophores; Kidney; Macrophages; Mice; Organophosphonates; Phospholipases A; Phospholipases A2; Recombinant Fusion Proteins | 2006 |
Neuroprotection of rat hippocampal slices exposed to oxygen-glucose deprivation by enrichment with docosahexaenoic acid and by inhibition of hydrolysis of docosahexaenoic acid-containing phospholipids by calcium independent phospholipase A2.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dentate Gyrus; Docosahexaenoic Acids; Enzyme Inhibitors; Hippocampus; Hydrolysis; Hypoxia-Ischemia, Brain; Male; Membrane Lipids; Naphthalenes; Neuroprotective Agents; Organ Culture Techniques; Organophosphonates; Phospholipases A; Phospholipases A2; Phospholipids; Prostaglandin Antagonists; Pyrones; Rats; Rats, Wistar | 2006 |
Biphasic regulation of extracellular signal-regulated kinases by scalaradial, a secretory phospholipase A(2) inhibitor.
Topics: Arachidonic Acid; Arachidonic Acids; Blotting, Western; Carcinoma, Hepatocellular; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Group II Phospholipases A2; Homosteroids; Humans; Immunoprecipitation; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organophosphonates; Phosphatidylcholines; Phospholipases A; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Sesterterpenes; Signal Transduction; Terpenes; Tumor Cells, Cultured | 2006 |
Arachidonic acid inhibits osteoblast differentiation through cytosolic phospholipase A2-dependent pathway.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Arachidonic Acid; Arachidonic Acids; Cell Differentiation; Cell Shape; Clone Cells; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprostone; Enzyme Inhibitors; Fibroblasts; Indomethacin; Mice; Nitrobenzenes; Organophosphonates; Osteoblasts; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Sulfonamides | 2007 |
Prostaglandin production in human coronary artery endothelial cells is modulated differentially by selective phospholipase A(2) inhibitors.
Topics: Arachidonic Acid; Arachidonic Acids; Coronary Vessels; Cyclooxygenase 2; Endothelial Cells; Enzyme Inhibitors; Humans; Organophosphonates; Phospholipases A; Prostaglandins | 2007 |
Interference by leptin with Helicobacter pylori lipopolysaccharide-induced cytosolic phospholipase A2 activation in gastric mucosal cells.
Topics: Androstadienes; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucins; Gastric Mucosa; Ginkgolides; Lactones; Leptin; Lipopolysaccharides; Organophosphonates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin | 2007 |
Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.
Topics: Arachidonic Acid; Arachidonic Acids; Boron Compounds; Breast; Calcium Channel Blockers; Cell Line, Transformed; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Nifedipine; Organophosphonates; Phospholipases A2, Cytosolic; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA, Messenger; RNA, Small Interfering; src-Family Kinases; Time Factors; Transfection | 2008 |
Lipid body mobilization in the ExoU-induced release of inflammatory mediators by airway epithelial cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Bronchi; Cell Line; Cytokines; Enzyme Inhibitors; Epithelial Cells; Humans; Inclusion Bodies; Inflammation Mediators; Lipid Metabolism; Organophosphonates; Prostaglandins E; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Calcium; Calcium Signaling; Cell Line; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Group IV Phospholipases A2; Humans; Lung; Lysophospholipids; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Respiratory Mucosa; rho-Associated Kinases; RNA, Small Interfering; Sphingosine | 2008 |
Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrogen Peroxide; Mice; Naphthalenes; Neocortex; Neurons; Organophosphonates; Oxidants; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipids; Pyrones; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances | 2008 |
Activation of phospholipase A2 is involved in indomethacin-induced damage in Caco-2 cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Caco-2 Cells; Cell Survival; Enzyme Inhibitors; Humans; Indomethacin; Lysophospholipids; Organophosphonates; Oxidative Stress; Phospholipases A2, Cytosolic | 2009 |
Contribution of Ras farnesyl transferase, MAP kinase and cytochrome P-450 metabolites to endothelin-1 induced hypertension.
Topics: Alkyl and Aryl Transferases; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 Enzyme System; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Unsaturated; Flavonoids; Hypertension; Infusions, Intravenous; Male; MAP Kinase Signaling System; Organophosphonates; Rats; Rats, Sprague-Dawley; Signal Transduction | 2011 |
Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly.
Topics: Arachidonic Acid; Arachidonic Acids; Blotting, Western; Cell Line; Cytosol; DNA Primers; Endoplasmic Reticulum; Gene Knockdown Techniques; Group IV Phospholipases A2; Hepacivirus; Humans; Immunoprecipitation; Microscopy, Fluorescence; Organophosphonates; Plasmids; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Viral Nonstructural Proteins; Virus Assembly; Virus Replication | 2012 |