organophosphonates has been researched along with aphidicolin in 3 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (aphidicolin) | Trials (aphidicolin) | Recent Studies (post-2010) (aphidicolin) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 1,647 | 3 | 136 |
| Protein | Taxonomy | organophosphonates (IC50) | aphidicolin (IC50) |
|---|---|---|---|
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain KOS | 0.438 | |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain 17 | 0.5 | |
| DNA polymerase catalytic subunit | Human herpesvirus 5 strain AD169 | 0.4435 | |
| DNA polymerase catalytic subunit | Human herpesvirus 3 strain Dumas | 1.6 | |
| DNA polymerase alpha catalytic subunit | Homo sapiens (human) | 2.98 | |
| DNA polymerase catalytic subunit | Human herpesvirus 6 (strain Uganda-1102) | 0.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holý, A; Kaminsky, R; Nickel, B | 1 |
| Cinatl, J; Doerr, HW; Kreuter, J; Langer, K; Michaelis, M; Rabenau, H; Vogel, JU | 1 |
| Brandt, B; Höltje, HD; Höltje, M; Richartz, A; Schäfer-Korting, M | 1 |
3 other study(ies) available for organophosphonates and aphidicolin
| Article | Year |
|---|---|
Arrest of Trypanosoma brucei rhodesiense and T. brucei brucei in the S-phase of the cell cycle by (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine ((S)-HPMPA).
Topics: Adenine; Animals; Aphidicolin; DNA, Kinetoplast; Organophosphonates; Organophosphorus Compounds; Pyruvates; S Phase; Thymidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense | 1998 |
In vitro antiviral activity of aphidicolin and its derivates. Synergistic effects of aphidicolin with other antiviral drugs.
Topics: Adenoviridae; Antiviral Agents; Aphidicolin; Cidofovir; Cytomegalovirus; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Herpesvirus 1, Human; Humans; Indicators and Reagents; Organophosphonates; Organophosphorus Compounds; Virus Replication | 2002 |
Targeting human DNA polymerase alpha for the inhibition of keratinocyte proliferation. Part 1. Homology model, active site architecture and ligand binding.
Topics: Adenine; Antiviral Agents; Aphidicolin; Binding Sites; Cell Division; DNA Polymerase I; Enzyme Inhibitors; Humans; Keratinocytes; Ligands; Models, Biological; Models, Molecular; Organophosphonates; Protein Conformation; Reverse Transcriptase Inhibitors | 2008 |