Compounds > organophosphonates
Page last updated: 2024-09-05

organophosphonates and anandamide

organophosphonates has been researched along with anandamide in 15 studies

Compound Research Comparison

Studies
(organophosphonates)		Trials
(organophosphonates)		Recent Studies (post-2010)
(organophosphonates)		Studies
(anandamide)		Trials
(anandamide)		Recent Studies (post-2010) (anandamide)
9,9688803,5962,56629957

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)anandamide (IC50)
Fatty-acid amide hydrolase 1Homo sapiens (human)3.75
Potassium channel subfamily K member 3Homo sapiens (human)3
Potassium channel subfamily K member 2 Bos taurus (cattle)1
Transient receptor potential cation channel subfamily V member 2Rattus norvegicus (Norway rat)4.78

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's10 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Petrocellis, L; Di Marzo, V; Kurahashi, Y; Marino, G; Maurelli, S; Melck, D; Ueda, N; Yamamoto, S1
Goparaju, SK; Ueda, N; Yamaguchi, H; Yamamoto, S1
Krebsbach, RJ; Schmid, HH; Schmid, PC; Schwindenhammer, D1
Goparaju, SK; Katayama, K; Kurahashi, Y; Suzuki, H; Ueda, N; Yamamoto, S1
Goparaju, SK; Taniguchi, K; Ueda, N; Yamamoto, S1
Beletskaya, I; Dasse, O; Deutsch, DG; Di Marzo, V; Jefferson, R; Mahadevan, A; Martin, BR; Patrick, G; Razdan, RK; Winckler, R1
Abumrad, N; Deutsch, DG; Glaser, ST; Hillard, CJ; Howell, JM; Kunz, JS; Puffenbarger, RA1
Bisogno, T; Davis, JB; De Petrocellis, L; Di Marzo, V; Finazzi-Agro, A; Maccarrone, M1
Di Marzo, V; Ligresti, A; Lutz, B; Monory, K; Morera, E; Ortar, G; Van Der Stelt, M1
Bagetta, G; Battista, N; Corasaniti, MT; Del Duca, C; Finazzi-Agrò, A; Maccarrone, M; Nappi, G; Piccirilli, S1
Alexander, SP; De Bank, PA; Kendall, DA1
Gatley, SJ; Gifford, AN; Glaser, ST1
Ho, WS; Randall, MD1
Imming, P1
Astarita, G; Clapper, JR; Duranti, A; Geaga, JA; King, AR; Luecke, H; Mor, M; Piomelli, D; Rivara, S; Rosengarth, A; Tarzia, G; Tontini, A1

Reviews

1 review(s) available for organophosphonates and anandamide

ArticleYear
A hydrolase enzyme inactivating endogenous ligands for cannabinoid receptors.
    The journal of medical investigation : JMI, 1998, Volume: 45, Issue:1-4

    Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; COS Cells; Dronabinol; Endocannabinoids; Enzyme Inhibitors; Esterases; Ethanolamine; Fatty Acids; Hydrolysis; Intestine, Small; Ligands; Liver; Nerve Tissue Proteins; Organ Specificity; Organophosphonates; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Recombinant Fusion Proteins; Swine

1998

Other Studies

14 other study(ies) available for organophosphonates and anandamide

ArticleYear
Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase.
    Biochemical and biophysical research communications, 1997, Feb-03, Volume: 231, Issue:1

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Basophils; Brain; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Mice; Neurons; Organophosphonates; Phospholipases A; Phospholipases A2; Polyunsaturated Alkamides; Rats; Tosyl Compounds; Tumor Cells, Cultured

1997
Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand.
    FEBS letters, 1998, Jan-23, Volume: 422, Issue:1

    Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; CHO Cells; Cricetinae; Diglycerides; Endocannabinoids; Enzyme Inhibitors; Gene Expression; Glycerides; Hydrogen-Ion Concentration; Kinetics; Liver; Organophosphonates; Phenylmethylsulfonyl Fluoride; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, Drug; Transfection

1998
Alternative pathways of anandamide biosynthesis in rat testes.
    Chemistry and physics of lipids, 1998, Volume: 92, Issue:1

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Calcium; Cell Membrane; Endocannabinoids; Ethanolamines; Fatty Acids; Male; Organophosphonates; Phosphatidylethanolamines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Testis

1998
Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors.
    Biochemical pharmacology, 1999, Feb-15, Volume: 57, Issue:4

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Brain; Cytosol; Endocannabinoids; Enzyme Inhibitors; Glycerides; Hydrogen-Ion Concentration; Ligands; Monoacylglycerol Lipases; Organophosphonates; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Substrate Specificity; Swine

1999
Cannabinoid properties of methylfluorophosphonate analogs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Analgesics, Opioid; Animals; Arachidonic Acids; Binding, Competitive; Brain; Cannabinoids; Chromatography, Liquid; Endocannabinoids; Glycerides; In Vitro Techniques; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Organophosphonates; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Spinal Cord; Time Factors

2000
The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase.
    The Journal of biological chemistry, 2001, Mar-09, Volume: 276, Issue:10

    Topics: Amidohydrolases; Arachidonic Acids; Binding Sites; Chromatography, Thin Layer; Endocannabinoids; Enzyme Inhibitors; Humans; Hydrolysis; Kinetics; Models, Biological; Organophosphonates; Polyunsaturated Alkamides; Time Factors; Transfection; Tumor Cells, Cultured

2001
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism.
    The Journal of biological chemistry, 2001, Apr-20, Volume: 276, Issue:16

    Topics: Arachidonic Acids; Biological Transport; Calcium; Cannabinoids; Capsaicin; Cell Line; Cell Membrane; Cytosol; Diterpenes; Endocannabinoids; Enzyme Inhibitors; Humans; Kinetics; Nitroprusside; Organophosphonates; Polyunsaturated Alkamides; Receptors, Drug; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transfection

2001
Further evidence for the existence of a specific process for the membrane transport of anandamide.
    The Biochemical journal, 2004, May-15, Volume: 380, Issue:Pt 1

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Biological Transport; Brain Chemistry; Carrier Proteins; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Endocannabinoids; Enzyme Inhibitors; Ganglia, Spinal; Humans; Kidney; Leukemia, Basophilic, Acute; Male; Mice; Mice, Knockout; Neoplasm Proteins; Organophosphonates; Polyunsaturated Alkamides; Rats; Synaptosomes; Thapsigargin

2004
Enhanced anandamide degradation is associated with neuronal apoptosis induced by the HIV-1 coat glycoprotein gp120 in the rat neocortex.
    Journal of neurochemistry, 2004, Volume: 89, Issue:5

    Topics: Amidohydrolases; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Carrier Proteins; Endocannabinoids; Enzyme Inhibitors; HIV Envelope Protein gp120; Injections, Intraventricular; Male; Neocortex; Neurons; Organophosphonates; Polyunsaturated Alkamides; Rats; Rats, Wistar

2004
A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening.
    Biochemical pharmacology, 2005, Apr-15, Volume: 69, Issue:8

    Topics: Amidohydrolases; Ammonia; Animals; Arachidonic Acids; Calcium Channel Blockers; Cannabinoids; Drug Evaluation, Preclinical; Endocannabinoids; Enzyme Inhibitors; Glutamic Acid; Hydrolysis; Kinetics; Liver; Oleic Acids; Organophosphonates; Phenylmethylsulfonyl Fluoride; Polyunsaturated Alkamides; Rats; Rats, Inbred Strains; Rats, Wistar; Spectrophotometry

2005
Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:3

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Autoradiography; Brain; Cerebrovascular Circulation; Endocannabinoids; Enzyme Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Organophosphonates; Polyunsaturated Alkamides; Tritium

2006
Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol.
    British journal of pharmacology, 2007, Volume: 150, Issue:5

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Glycerides; Hydrolases; In Vitro Techniques; Lectins; Lectins, C-Type; Male; Membrane Proteins; Mesenteric Artery, Superior; Organophosphonates; Polyunsaturated Alkamides; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Receptors, Cell Surface; Vasodilation; Vasodilator Agents

2007
Fatty pain cures.
    Chemistry & biology, 2007, Volume: 14, Issue:12

    Topics: Amidohydrolases; Analgesics; Animals; Arachidonic Acids; Biphenyl Compounds; Brain; Cannabinoid Receptor Agonists; Cannabinoid Receptor Modulators; Endocannabinoids; Enzyme Inhibitors; Glycerides; Humans; Monoacylglycerol Lipases; Organophosphonates; Pain; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid

2007
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
    Chemistry & biology, 2007, Volume: 14, Issue:12

    Topics: Amides; Animals; Arachidonic Acids; Biphenyl Compounds; Brain; Catalysis; Cerebellum; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Glycerides; HeLa Cells; Hippocampus; Humans; Kinetics; Male; Monoacylglycerol Lipases; Organophosphonates; Palmitic Acids; Polyunsaturated Alkamides; Rats; Rats, Wistar; Recombinant Proteins; Structure-Activity Relationship; Transfection

2007