Page last updated: 2024-09-05

organophosphonates and acyclovir

organophosphonates has been researched along with acyclovir in 114 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(acyclovir)
Trials
(acyclovir)
Recent Studies (post-2010) (acyclovir)
9,9688803,5969,6681,0072,368

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19904 (3.51)18.7374
1990's38 (33.33)18.2507
2000's45 (39.47)29.6817
2010's25 (21.93)24.3611
2020's2 (1.75)2.80

Authors

AuthorsStudies
Andrei, G; De Clercq, E; Desmyter, J; Goubau, P; Snoeck, R1
Awan, AR; de la Fuente, R; Field, HJ1
Kern, ER1
De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R1
De Clercq, E; Holý, A1
Bernaerts, R; Holý, A; Hrebabecký, H; Merta, A; Otmar, M; Rosenberg, I; Votruba, I1
Anisimová, E; Cerný, J; Holý, A; Rosenberg, I; Vonka, V; Votruba, I1
Azuma, M; Sakuma, T1
de Clercq, E3
Barker, MF; Duke, AE; Martin, JC; Matthews, TR; McGee, DP; Prisbe, EJ; Smee, DF; Verheyden, JP1
Hovi, T1
Barnett, BB; Holy, A; Reist, EJ; Sidwell, RW; Smee, DF1
Mimura, Y; Naito, T; Nitta, K; Shiota, H1
Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G1
Davidson, JM; Drew, WL; Fisher, PE; Glutzer, E; Jaffe, HS; Lalezari, JP; Miner, D; Owen, WF; Safrin, S1
Bravo, FJ; Kern, ER; Kier, AB; Stanberry, LR; Vogt, PE1
Barkhimer, DB; Chen, MS; Mendel, DB1
Reusser, P1
Andrei, G; De Clercq, E; Snoeck, R2
Cassady, KA; Whitley, RJ1
Ganem, D; Kedes, DH1
Horvath, E; Lund, T; Medveczky, MM; Medveczky, PG1
Boggs, J; Cheung, T; Corey, L; Drew, WL; Feinberg, J; Gathe, J; Jaffe, HS; Kessler, H; Kramer, F; Lalezari, J; Lee, S; McGuire, B; Safrin, S; Schacker, T1
Luks-Golger, DB; Martinez, CM1
De Clercq, E; Neyts, J1
Levine, JF; LoPresti, AE; Mendel, DB; Munk, GB; Tai, CY1
Kaufman, HE; Thompson, HW; Varnell, ED1
Don, PC; Kaufmann, M; Lateef, F; Weinberg, JM; White, SM1
De Clercq, E; Holý, A; Meerbach, A; Neyts, J; Wutzler, P1
Bartels, SP; Gordon, YJ; Romanowski, EG1
Girardet, JL; Gosselin, G; Imbach, JL; Korba, BE; Périgaud, C1
Borel, C; Gosselin, G; Hantz, O; Imbach, JL; Jamard, C; Périgaud, C; Trépo, C; Zoulim, F1
Afouna, MI; DeClercq, E; El-Shattawy, HH; Ghanem, AH; Higuchi, WI; Kern, ER; Mehta, SC1
Cheng, YC; Fu, L; Liu, SH1
Carrilho, FJ; Kato, N; Lan, KH; Omata, M; Ono-Nita, SK; Shiratori, Y; Yoshida, H1
Keating, MR1
Civitico, G; Colledge, D; Locarnini, S; Shaw, T1
De Clercq, E; Neyts, J; Ying, C1
De Clercq, E; Furman, P; Neyts, J; Nicholson, W; Ying, C1
Einsele, H; Hebart, H1
Aymard, M; Chen, Y; Devergie, A; Espérou, H; Garderet, L; Garrait, V; Gluckman, E; Hocqueloux, L; Leleu, G; Molina, JM; Morfin, F; Morinet, F; Ribaud, P; Rocha, V; Scieux, C; Sélimi, F; Socié, G; Thouvenot, D1
Blot, N; Dehesdin, D; Janvresse, C; Schneider, P; Tron, P; Vannier, JP; Young, P1
Eizuru, Y; Minamishima, Y; Minematsu, T; Mori, S1
Arnold, E; Das, K; Gibbs, CS; Sarafianos, SG; Westland, CE; Xiong, X; Yang, H1
Torres, G1
Bowers, M1
Fujiwara, T; Kaneko, H; Mori, S; Shigeta, S1
Bordigoni, P; Carret, AS; Corsaro, D; Dauendorffer, JN; Edert, D; Le Faou, A; Venard, V1
Bryant, P; Carapetis, J; Curtis, N; Sasadeusz, J; Waters, K1
Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B1
De Clercq, E; Naesens, L1
Geusau, A; Kopp, T; Rieger, A; Stingl, G1
Snoeck, R1
Zaia, JA2
De Clercq, E; Kurane, I; Maeda, A; Morikawa, S; Niikura, M; Saijo, M; Suzutani, T1
Emery, VC; Leśnikowski, ZJ; Olejniczak, A; Paradowska, E; Przepiórkiewicz, M1
Morfin, F; Thouvenot, D1
Afouna, MI; Fincher, TK; Reddy, IK; Zaghloul, AA1
Bidanset, DJ; Kern, ER; Kushner, NL; Long, MC; Williams, SL1
Bakker, HI; De Boer, FM; Harmsen, MC; Meijer, DK; Molema, G; van der Strate, BW1
Chilukuri, S; Rosen, T1
Andronova, VL; Galegov, GA; Ivanov, AV; Jasko, MV; Karpenko, IL; Kukhanova, MK; Skoblov, YS1
Boeckh, M; Nichols, WG; Papanicolaou, G; Rubin, R; Wingard, JR; Zaia, J1
Eksborg, S1
Lajusticia, J; Ramos, C1
Clarke, HE; Maggs, DJ1
De Clercq, E; Friedrichs, C; Gaspar, G; Neyts, J; Wutzler, P1
Dediulescu, DF; Dediulescu, L1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM1
Cohen, J1
Goh, CL; Tan, HH1
Alessi, E; Cusini, M; Ghislanzoni, M; Zerboni, R1
Croubels, S; De Backer, P; Garré, B; Nauwynck, H; Neyts, J; Nugent, J; van der Meulen, K1
Challacombe, SJ; Woo, SB1
Andrei, G; De Clercq, E; Fiten, P; Gordts, B; Goubau, P; Opdenakker, G; Selleslag, D; Snoeck, R; van Landuyt, H1
Andronova, VL; Galegov, GA; Jasko, MV; Karpenko, IL; Kukhanova, MK; Myasoedov, NF; Sidorov, GV; Skoblov, YS1
Boivin, G; Sergerie, Y1
Cieśluk, B; Dzieciatkowski, T; Majewska, A; Łuczak, M1
Járay, J; Péter, A; Telkes, G; Varga, M1
Cowan, MJ; Dvorak, CC; Horn, B; Weintrub, PS1
Bernardin, R; Castelo-Soccio, L; Goldstein, SA; Kovarik, C; Stern, J1
Deinhardt, S; Sauerbrei, A; Wutzler, P; Zell, R1
Beer, M; Eyrich, M; Gattenlöhner, S; Girschick, HJ; Liese, J; Schick, J; Schlegel, PG; Weissbrich, B; Wiegering, V1
Hartline, CB; Kern, ER; Lanier, ER; Prichard, MN; Quenelle, DC1
Razonable, RR1
Baum, MM; Butkyavichene, I; Clark, MR; Friend, DR; Gilman, J; Kennedy, S; Kopin, E; Malone, AM; Moss, JA; Motamedi, M; Nguyen, C; Smith, TJ; Vincent, KL1
Bahar, MS; Boltežar, IH; Gale, N; Matičič, M; Poljak, M; Zargi, M1
Bohn, K; Hamprecht, K; Heim, A; Hoffmann, D; Hofmann, J; Jahn, G; Sauerbrei, A; Schnitzler, P; Weissbrich, B; Wutzler, P; Zell, R1
Evans, KG; Goldstein, SC; Kim, EJ; Morrissey, KA; Rook, AH; Vittorio, CC1
Baum, MM; Butkyavichene, I; Clark, MR; Friend, DR; Gilman, J; Kennedy, S; Kopin, E; Malone, AM; Moss, JA; Nguyen, C; Smith, TJ1
Armistead, P; Dean, A; Khan, T; Muluneh, B1
Bastide, C; Bruyère, F; Chandenier, J; Desoubeaux, G; Fourcade, C; Guy, L; Karsenty, G; Lachaud, L; Lavigne, JP; Malavaud, S; Sotto, A1
Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D1
Boivin, G; Piret, J1
Alt, C; Shankar, GN1
de Alencastro, RB; de Souza, FR; França, TC; Gonçalves, AS; Guimarães, AP; Oliveira, AA; Ramalho, TC1
Andronova, VL; Deryabin, PG; Galegov, GA; Jasko, MV; Kukhanova, MK; Skoblov, YS1
Fort, MW; Ledbetter, EC; Pennington, MR; Van de Walle, GR1
Hartline, CB; Larson, RA; Mommeja-Marin, H; Mullane, KM; Nuss, C; Prichard, MN; Ridgeway, J; Theusch, J1
Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S1
Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY1
Rosen, T1
Andronova, VL; Charushin, VN; Denisova, AO; Galegov, GA; Kayushin, AL; Kharitonova, MI; Konstantinova, ID; Kotovskaya, SK; Miroshnikov, AI1
Cao, Y; Chen, J; Fu, W; Li, H; Pang, J; Wu, T; Zhou, P1
Andrei, G; Gillemot, S; Snoeck, R; Topalis, D1
Fan, J; Kashemirov, BA; Liu, D; Lloyd, MG; Lyu, J; McKenna, CE; Moffat, JF; Overhulse, JM; Prichard, MN1
Kotton, BD; Kotton, CN1

Reviews

25 review(s) available for organophosphonates and acyclovir

ArticleYear
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
    Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3

    Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication

1991
Virus-drug resistance: thymidine kinase-deficient (TK-) mutants of herpes simplex virus. Therapeutic approaches.
    Annali dell'Istituto superiore di sanita, 1987, Volume: 23, Issue:4

    Topics: Acyclovir; Adenine; Antiviral Agents; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins

1987
Antivirals for the treatment of herpesvirus infections.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 32 Suppl A

    Topics: Acyclovir; Antiviral Agents; Belgium; Bromodeoxyuridine; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds

1993
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options.
    The Journal of hospital infection, 1996, Volume: 33, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

1996
New therapeutic approaches to the alphaherpesvirus infections.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2

    Topics: 2-Aminopurine; Acyclovir; Alphaherpesvirinae; Antibodies, Monoclonal; Arabinofuranosyluracil; Cidofovir; Cytosine; Famciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

1997
Cidofovir use in acyclovir-resistant herpes infection.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:12

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1997
Antiviral agents for non-human immunodeficiency virus infections.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir

1999
Cytomegalovirus infection following stem cell transplantation.
    Haematologica, 1999, Volume: 84 Suppl EHA-4

    Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency

1999
Recent developments in herpesvirus therapy.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine

2001
[Perspectives for the treatment and prevention of herpes simplex infections].
    Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:4 Pt 2

    Topics: 2-Aminopurine; Acyclovir; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Famciclovir; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Imiquimod; Interferon Inducers; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine

2002
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation.
    Bone marrow transplantation, 2002, Volume: 29, Issue:8

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors

2002
[Drugs against human cytomegalovirus].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:75

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drugs, Investigational; Female; Foscarnet; Ganciclovir; Global Health; Humans; Infectious Disease Transmission, Vertical; Naphthalenesulfonates; Organophosphonates; Organophosphorus Compounds; Pregnancy; Pregnancy Complications, Infectious; Thionucleotides; Valacyclovir; Valganciclovir; Valine

2002
Herpes simplex virus resistance to antiviral drugs.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 26, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Herpes Simplex; Humans; Immunocompromised Host; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins; Virus Replication

2003
Management of acyclovir-resistant herpes simplex virus.
    Dermatologic clinics, 2003, Volume: 21, Issue:2

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Stomatitis, Herpetic; Trifluridine; Vidarabine

2003
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2003, Volume: 9, Issue:9

    Topics: Acyclovir; Antigens, CD34; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Immunotherapy; Lymphocyte Depletion; Organophosphonates; Organophosphorus Compounds; Transplantation Conditioning

2003
The pharmacokinetics of antiviral therapy in paediatric patients.
    Herpes : the journal of the IHMF, 2003, Volume: 10, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Child, Hospitalized; Cidofovir; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Virus Diseases

2003
[Antiherpetic therapy].
    Oftalmologia (Bucharest, Romania : 1990), 2005, Volume: 49, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Drug Combinations; Famciclovir; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Oligonucleotides; Ophthalmic Solutions; Organophosphonates; Treatment Outcome; Valacyclovir; Valine; Vidarabine

2005
Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies.
    American journal of clinical dermatology, 2006, Volume: 7, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Schedule; Epstein-Barr Virus Infections; Famciclovir; Foscarnet; Herpes Zoster; Herpesviridae Infections; Humans; Immunocompromised Host; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Papillomavirus Infections; Skin Diseases, Viral; Trifluridine; Valacyclovir; Valine

2006
Management of recurrent oral herpes simplex infections.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103 Suppl

    Topics: Acyclovir; Antiviral Agents; Bell Palsy; Cidofovir; Cytosine; Erythema Multiforme; Herpes Labialis; Humans; Immunocompromised Host; Organophosphonates; Secondary Prevention; Sunscreening Agents; Time Factors; Valacyclovir; Valine

2007
The discovery of antiviral agents: ten different compounds, ten different stories.
    Medicinal research reviews, 2008, Volume: 28, Issue:6

    Topics: Acyclovir; Adenine; Antiviral Agents; Benzodiazepines; Benzylamines; Cidofovir; Cyclams; Cytosine; Heterocyclic Compounds; Humans; Imidazoles; Nucleosides; Organophosphonates; Tenofovir; Valacyclovir; Valine; Virus Diseases

2008
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
    Orvosi hetilap, 2008, Dec-21, Volume: 149, Issue:52

    Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir

2008
Antiviral drugs for viruses other than human immunodeficiency virus.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:10

    Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir

2011
[Non-antibiotic anti-infectious treatments in urology].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:15

    Topics: Acyclovir; Albendazole; Amphotericin B; Anti-Infective Agents; Caspofungin; Cidofovir; Cytosine; Echinocandins; Fluconazole; Flucytosine; Foscarnet; Ganciclovir; Humans; Ivermectin; Lipopeptides; Organophosphonates; Praziquantel; Urologic Diseases; Valganciclovir

2013
Antiviral drug resistance in herpesviruses other than cytomegalovirus.
    Reviews in medical virology, 2014, Volume: 24, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates

2014
Resistant herpes simplex virus infections - who, when, and what's new?
    Current opinion in infectious diseases, 2022, 12-01, Volume: 35, Issue:6

    Topics: Acyclovir; Antiviral Agents; Cytosine; Foscarnet; Herpes Simplex; Herpesviridae Infections; Humans; Organophosphonates

2022

Trials

2 trial(s) available for organophosphonates and acyclovir

ArticleYear
A randomized, double-blind, placebo-controlled trial of cidofovir gel for the treatment of acyclovir-unresponsive mucocutaneous herpes simplex virus infection in patients with AIDS.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Double-Blind Method; Drug Resistance, Microbial; Female; Foscarnet; Gels; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Mucosa; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells

1997
Opportunistic infection highlights from the 35th ICAAC.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bacterial Vaccines; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Ganciclovir; HIV; Humans; Influenza Vaccines; Mycobacterium avium-intracellulare Infection; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pneumonia, Pneumocystis; Randomized Controlled Trials as Topic; United States; Valacyclovir; Valine; Viremia

1995

Other Studies

87 other study(ies) available for organophosphonates and acyclovir

ArticleYear
Comparative activity of various compounds against clinical strains of herpes simplex virus.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1992, Volume: 11, Issue:2

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Dextran Sulfate; Guanine; HeLa Cells; Heparin; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Rabbits; Simplexvirus; Virus Replication

1992
The acyclic nucleoside analogue penciclovir is a potent inhibitor of equine herpesvirus type 1 (EHV-1) in tissue culture and in a murine model.
    Antiviral research, 1992, Volume: 18, Issue:1

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Line; Drug Resistance, Microbial; Female; Guanine; Herpesviridae Infections; Herpesvirus 1, Equid; Lung; Mice; Mice, Inbred BALB C; Mutation; Organophosphonates; Organophosphorus Compounds; Rabbits; Thymidine Kinase

1992
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
    Journal of virological methods, 1991, Volume: 35, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin

1991
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Peritoneal Cavity; Skin Diseases, Infectious

1991
Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues.
    Antiviral research, 1990, Volume: 13, Issue:5

    Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Dideoxynucleotides; DNA Polymerase I; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymine Nucleotides; Zidovudine

1990
Properties of a 9-(2-phosphonylmethoxyethyl)adenine (PMEA)-resistant herpes simplex virus type 1 virus mutant.
    Antiviral research, 1990, Volume: 14, Issue:2

    Topics: Acyclovir; Adenine; Animals; Bromodeoxyuridine; Drug Resistance, Microbial; Mutation; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells; Virus Replication

1990
[Chemotherapy of cytomegalovirus infections].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:2

    Topics: Acyclovir; Adenine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid

1989
Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Acyclovir; Administration, Oral; Animals; Cell Line; Cytomegalovirus; Female; Ganciclovir; Haplorhini; Humans; In Vitro Techniques; Injections, Subcutaneous; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Organophosphonates; Phosphates; Simplexvirus; Thymidine Kinase

1986
Drug-resistant herpesvirus mutants -- tough or bluff?
    Medical biology, 1982, Volume: 60, Issue:4

    Topics: Acyclovir; DNA Replication; DNA, Viral; Drug Resistance, Microbial; Mutation; Organophosphonates; Simplexvirus; Thymidine Kinase; Vidarabine; Virus Replication

1982
Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus.
    Antiviral research, 1995, Volume: 26, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Mice; Mice, SCID; Microbial Sensitivity Tests; Muromegalovirus; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds

1995
[Sensitivities to other antiviral drugs and thymidine kinase activity of aciclovir-resistant herpes simplex virus type 1].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:6

    Topics: Acyclovir; Adenine; Antiviral Agents; Drug Resistance, Microbial; Ganciclovir; Guanine; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Thymidine Kinase; Vidarabine

1994
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; DNA Restriction Enzymes; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral; Thymidine Kinase

1994
Treatment with intravenous (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine of acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with AIDS.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:3

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus

1994
Evaluation of HPMPC therapy for primary and recurrent genital herpes in mice and guinea pigs.
    Antiviral research, 1993, Volume: 21, Issue:1

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Herpes Genitalis; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Ultraviolet Rays; Vagina; Vaginal Diseases; Virus Replication

1993
Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:9

    Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Drug Resistance, Microbial; Fibroblasts; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Plaque Assay

1995
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:7

    Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid

1996
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.
    The Journal of clinical investigation, 1997, May-01, Volume: 99, Issue:9

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA Probes; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Methylurea Compounds; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Phorbol Esters; Pyridines; Sarcoma, Kaposi; Tumor Cells, Cultured; Valine; Virus Replication

1997
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006

    Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases

1997
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.
    AIDS (London, England), 1997, Volume: 11, Issue:11

    Topics: Acyclovir; Antiviral Agents; Carcinogens; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phorbol 12,13-Dibutyrate; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Virus Latency

1997
In vitro and in vivo inhibition of murine gamma herpesvirus 68 replication by selected antiviral agents.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Chlorocebus aethiops; Cidofovir; Cytosine; Gammaherpesvirinae; Herpesviridae Infections; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vero Cells; Virus Replication

1998
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:2

    Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Organophosphonates; Organophosphorus Compounds

1998
Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Female; Guanine; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ointments; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine

1998
Treatment of acyclovir-resistant, foscarnet-unresponsive HSV infection with topical cidofovir in a child with AIDS.
    Archives of dermatology, 1998, Volume: 134, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Anti-HIV Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistance, Microbial; Facial Dermatoses; Foscarnet; Herpes Simplex; Humans; Male; Organophosphonates; Organophosphorus Compounds; Treatment Failure

1998
Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cell Line; DNA Replication; DNA, Viral; Ganciclovir; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; Molecular Structure; Nucleic Acid Hybridization; Nucleosides; Nucleotides; Organophosphonates; Purines; Virus Replication; Zidovudine

1998
Comparative antiviral efficacies of cidofovir, trifluridine, and acyclovir in the HSV-1 rabbit keratitis model.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:2

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Female; Herpesvirus 1, Human; Keratitis, Dendritic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Trifluridine; Virus Replication; Virus Shedding

1999
The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir.
    Antiviral research, 1999, Volume: 40, Issue:3

    Topics: Acyclovir; Antiviral Agents; Drug Evaluation, Preclinical; Drug Synergism; Hepatitis B virus; Hepatoblastoma; Humans; Lamivudine; Liver Neoplasms; Microbial Sensitivity Tests; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured

1999
The SATE pronucleotide approach applied to acyclovir: part II. Effects of bis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo.
    Antiviral research, 1999, Volume: 40, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Blotting, Southern; Cells, Cultured; DNA, Viral; Drug Evaluation, Preclinical; Ducks; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Liver; Nucleotides; Organophosphonates; Prodrugs; Virus Replication

1999
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice.
    Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:5

    Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral

1999
Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues.
    Biochemical pharmacology, 1999, Jun-15, Volume: 57, Issue:12

    Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Guanine; Hepatitis B virus; Lamivudine; Microbial Sensitivity Tests; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Zalcitabine

1999
Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors.
    The Journal of clinical investigation, 1999, Volume: 103, Issue:12

    Topics: Acyclovir; Adenine; Carcinoma, Hepatocellular; Drug Resistance, Microbial; Guanine; Hepatitis B virus; Humans; Lamivudine; Mutagenesis, Site-Directed; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Transfection; Tumor Cells, Cultured

1999
In vitro antihepadnaviral activities of combinations of penciclovir, lamivudine, and adefovir.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cells, Cultured; Drug Interactions; Drug Therapy, Combination; Ducks; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Humans; Lamivudine; Liver; Organophosphonates; Virus Replication

2000
Lamivudine, adefovir and tenofovir exhibit long-lasting anti-hepatitis B virus activity in cell culture.
    Journal of viral hepatitis, 2000, Volume: 7, Issue:1

    Topics: Acyclovir; Adenine; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Guanine; Hepatitis B virus; Lamivudine; Organophosphonates; Organophosphorus Compounds; Tenofovir; Tumor Cells, Cultured

2000
Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir.
    Journal of viral hepatitis, 2000, Volume: 7, Issue:2

    Topics: Acyclovir; Adenine; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Cell Line; Dioxolanes; DNA-Directed DNA Polymerase; DNA, Viral; Guanine; Hepatitis B virus; Humans; Organophosphonates; Organophosphorus Compounds; Purine Nucleosides; Tenofovir; Virus Replication

2000
Resistant herpes simplex virus type 1 infection: an emerging concern after allogeneic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:4

    Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Drug Resistance, Microbial; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Transplantation, Homologous

2000
Treatment of an acyclovir and foscarnet-resistant herpes simplex virus infection with cidofovir in a child after an unrelated bone marrow transplant.
    Bone marrow transplantation, 2000, Volume: 26, Issue:8

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance; Female; Foscarnet; Herpes Simplex; Humans; Infant; Organophosphonates; Organophosphorus Compounds

2000
Isolation and analysis of an aciclovir-resistant murine cytomegalovirus mutant.
    Antiviral research, 2001, Volume: 49, Issue:1

    Topics: Acyclovir; Amino Acid Substitution; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Codon; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Ganciclovir; Inhibitory Concentration 50; Mice; Muromegalovirus; Mutation; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Virus Replication

2001
Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC).
    Journal of virology, 2001, Volume: 75, Issue:10

    Topics: Acyclovir; Adenine; Amino Acid Sequence; Antiviral Agents; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleotides; Drug Resistance, Microbial; Emtricitabine; Guanine; Hepatitis B virus; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Organophosphonates; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid

2001
Herpesviruses.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Complementary Therapies; Cytosine; Famciclovir; Foscarnet; Herpesviridae Infections; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine; Viral Vaccines

1995
Acyclovir-resistant herpes: expanded access available for cidofovir gel (Forvade).
    AIDS treatment news, 1997, Feb-07, Issue:No 264

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Gels; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds

1997
[Evaluation of antiviral agents for adenovirus using the MTT method in vitro].
    Nippon Ganka Gakkai zasshi, 2000, Volume: 104, Issue:11

    Topics: Acyclovir; Adenoviridae; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Foscarnet; Humans; Organophosphonates; Organophosphorus Compounds; Zalcitabine

2000
Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation.
    Pathologie-biologie, 2001, Volume: 49, Issue:7

    Topics: Acute Disease; Acyclovir; Adolescent; Amino Acid Substitution; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Codon; Cytosine; DNA Mutational Analysis; Drug Resistance, Viral; Female; Foscarnet; Graft vs Host Disease; Herpes Simplex; Humans; Immunocompromised Host; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Point Mutation; Salvage Therapy; Simplexvirus; Thymidine Kinase; Transplantation, Homologous; Valacyclovir; Valine; Viral Proteins; Virus Activation

2001
Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis

2001
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation

2001
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 2002, Feb-04, Volume: 44, Issue:1123

    Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Amantadine; Animals; Antiviral Agents; Cidofovir; Cytosine; Famciclovir; Foscarnet; Guanine; Herpesviridae Infections; Humans; Influenza, Human; Injections, Intravenous; Lamivudine; Organophosphonates; Organophosphorus Compounds; Rats; Ribavirin; Rimantadine; Thionucleotides; Trifluridine; Valacyclovir; Valine

2002
Successful treatment of an aciclovir-resistant herpes simplex type 2 infection with cidofovir in an AIDS patient.
    The British journal of dermatology, 2002, Volume: 147, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Fissure in Ano; Herpes Simplex; Herpesvirus 2, Human; Humans; Organophosphonates; Organophosphorus Compounds

2002
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Oct-15, Volume: 35, Issue:8

    Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine

2002
Genotypic and phenotypic characterization of the thymidine kinase of ACV-resistant HSV-1 derived from an acyclovir-sensitive herpes simplex virus type 1 strain.
    Antiviral research, 2002, Volume: 56, Issue:3

    Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Blotting, Western; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Resistance, Viral; Herpesvirus 1, Human; Molecular Sequence Data; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA; Thymidine Kinase; Vero Cells; Viral Plaque Assay

2002
Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice.
    International journal of pharmaceutics, 2003, Mar-06, Volume: 253, Issue:1-2

    Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Topical; Animals; Antiviral Agents; Azepines; Cidofovir; Cytosine; Drug Administration Schedule; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Permeability; Skin Absorption

2003
Determination of antiviral efficacy against lymphotropic herpesviruses utilizing flow cytometry.
    Antiviral research, 2003, Volume: 58, Issue:2

    Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds

2003
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro.
    Antiviral research, 2003, Volume: 58, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds

2003
Synthesis and antiherpetic activity of acyclovir phosphonates.
    Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Herpesvirus 1, Human; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Organophosphates; Organophosphonates; Vero Cells

2003
[Infection due to acyclovir-resistant varicella-zoster herpes virus in a patient with AIDS].
    Enfermedades infecciosas y microbiologia clinica, 2004, Volume: 22, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Fatal Outcome; Female; Foscarnet; Herpes Zoster; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Organophosphonates

2004
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.
    American journal of veterinary research, 2004, Volume: 65, Issue:4

    Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication

2004
Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.
    Antiviral research, 2004, Volume: 62, Issue:3

    Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction

2004
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
    Antiviral research, 2004, Volume: 61, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Adenine; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Foscarnet; Guanine; Herpesvirus 3, Human; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Phenotype; Selection, Genetic; Thymidine Kinase; Viral Proteins

2004
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
    The Journal of general virology, 2005, Volume: 86, Issue:Pt 8

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication

2005
HIV/AIDS. Prevention cocktails: combining tools to Stop HIV's spread.
    Science (New York, N.Y.), 2005, Aug-12, Volume: 309, Issue:5737

    Topics: Acyclovir; Adenine; Anti-HIV Agents; Antidepressive Agents, Second-Generation; Antiviral Agents; Bupropion; Circumcision, Male; Clinical Trials as Topic; Contraceptive Devices, Female; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV; HIV Infections; Humans; Hygiene; Male; Organophosphonates; Sexual Behavior; Tenofovir; Viral Load

2005
Chronic hypertrophic acyclovir-resistant genital herpes treated with topical cidofovir and with topical foscarnet at recurrence in an HIV-positive man.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:7

    Topics: Acyclovir; Administration, Topical; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chronic Disease; Cidofovir; Cytosine; Drug Resistance, Viral; Drug Therapy, Combination; Foscarnet; Herpes Genitalis; HIV Infections; Humans; Male; Middle Aged; Organophosphonates

2006
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
    Veterinary microbiology, 2007, May-16, Volume: 122, Issue:1-2

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates

2007
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:2

    Topics: Acyclovir; Adolescent; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections

2007
Cell metabolism of acyclovir phosphonate derivatives and antiherpesvirus activity of their combinations with alpha2-interferon.
    Chemical biology & drug design, 2007, Volume: 69, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Chemistry, Pharmaceutical; Chlorocebus aethiops; Chromatography; Drug Design; Herpesviridae; Interferon-alpha; Kinetics; Models, Biological; Organophosphonates; Phosphorylation; Purine-Nucleoside Phosphorylase; Vero Cells

2007
Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes.
    Antiviral research, 2008, Volume: 77, Issue:1

    Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Combinations; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Humans; Hydroxyurea; Mutation; Organophosphonates; Ribonucleotide Reductases; Thymidine Kinase

2008
[In vitro acyclovir and cidofovir susceptibilities of human herpesvirus type 1 clinical isolates].
    Medycyna doswiadczalna i mikrobiologia, 2008, Volume: 60, Issue:2

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Herpes Simplex; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Vero Cells

2008
Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Oct-15, Volume: 49, Issue:8

    Topics: Acyclovir; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Male; Organophosphonates; Simplexvirus; Stem Cell Transplantation; Stomatitis; Treatment Outcome

2009
Successful treatment of acyclovir-resistant herpes simplex virus with intralesional cidofovir.
    Archives of dermatology, 2010, Volume: 146, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Facial Dermatoses; Herpes Simplex; Humans; Injections, Intralesional; Male; Organophosphonates

2010
Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus.
    Antiviral research, 2010, Volume: 86, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Guanine; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Mutation, Missense; Organophosphonates; Oxidation-Reduction; Sequence Analysis, DNA; Staining and Labeling; Tetrazolium Salts; Thymidine Kinase; Viral Proteins

2010
Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis.
    BMC pediatrics, 2011, May-10, Volume: 11

    Topics: Acyclovir; Antiviral Agents; Chickenpox; Child; Child, Preschool; Cidofovir; Cytosine; Female; Herpes Zoster; Herpesvirus 3, Human; Hospitalization; Humans; Immunocompromised Host; Incidence; Infant; Male; Organophosphonates; Practice Guidelines as Topic

2011
CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infections.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10

    Topics: Acyclovir; Animals; Antiviral Agents; Cells, Cultured; Cytosine; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mice; Mice, Inbred BALB C; Organophosphonates

2011
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Acyclovir; Adenine; Administration, Intravaginal; Animals; Anti-HIV Agents; Antiviral Agents; Delayed-Action Preparations; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Equipment Design; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Organophosphonates; Rabbits; Sexually Transmitted Diseases, Viral; Tenofovir; Treatment Outcome

2012
Adjuvant therapy for laryngeal papillomatosis.
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2011, Volume: 20, Issue:3

    Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antiviral Agents; Chemotherapy, Adjuvant; Child; Child, Preschool; Cidofovir; Cytosine; Female; Humans; Indoles; Infant; Laryngeal Diseases; Male; Middle Aged; Organophosphonates; Papilloma; Papillomavirus Vaccines; Vaccination; Valacyclovir; Valine

2011
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Child; Child, Preschool; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Foscarnet; Genotype; Guanine; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Thymidine Kinase; Viral Proteins

2011
Chronic acyclovir-resistant HSV-2 ulcer in an immunosuppressed patient treated with topical cidofovir.
    Archives of dermatology, 2011, Volume: 147, Issue:12

    Topics: Acyclovir; Administration, Cutaneous; Aged; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Fissure in Ano; Herpesvirus 2, Human; Humans; Immunocompromised Host; Lymphoma, Mantle-Cell; Male; Organophosphonates; Stem Cell Transplantation

2011
An intravaginal ring for the simultaneous delivery of multiple drugs.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:8

    Topics: Acyclovir; Adenine; Administration, Intravaginal; Animals; Antiviral Agents; Delayed-Action Preparations; Drug Delivery Systems; Equipment Design; Female; HIV; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Silicon; Tenofovir; Tensile Strength

2012
Successful clearance of cutaneous acyclovir-resistant, foscarnet-refractory herpes virus lesions with topical cidofovir in an allogeneic hematopoietic stem cell transplant patient.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:2

    Topics: Acyclovir; Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Gels; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Real-Time Polymerase Chain Reaction; Transplantation, Homologous; Treatment Outcome

2013
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:9

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Follow-Up Studies; Foscarnet; Herpes Simplex; HIV Infections; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Retrospective Studies; Skin Diseases, Viral; Skin Ulcer; Socioeconomic Factors; Thymidine Kinase; Treatment Outcome

2014
Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:12

    Topics: Acrylic Resins; Acyclovir; Adenine; Animals; Anti-Infective Agents; Chlorocebus aethiops; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Female; Herpes Genitalis; Herpesvirus 2, Human; Mice, Inbred BALB C; Organophosphonates; Poloxamer; Rabbits; Rats, Sprague-Dawley; Tenofovir; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Vero Cells

2014
Design of inhibitors of thymidylate kinase from Variola virus as new selective drugs against smallpox.
    European journal of medicinal chemistry, 2015, Feb-16, Volume: 91

    Topics: Acyclovir; Antiviral Agents; Catalytic Domain; Cidofovir; Cytosine; Drug Design; Humans; Kinetics; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Nucleoside-Phosphate Kinase; Organophosphonates; Small Molecule Libraries; Smallpox; Species Specificity; Structure-Activity Relationship; Thermodynamics; Variola virus; Viral Proteins

2015
[Research of suppression of the herpes simplex virus reproduction with drug resistance by combination phosphite of acycloguanosine with some antiherpetic drugs].
    Voprosy virusologii, 2014, Volume: 59, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Foscarnet; Glycyrrhizic Acid; Herpesvirus 1, Human; Humans; Interferon-alpha; Organophosphonates; Phosphites; Ribavirin; Vero Cells; Vidarabine; Virus Replication

2014
A novel corneal explant model system to evaluate antiviral drugs against feline herpesvirus type 1 (FHV-1).
    The Journal of general virology, 2016, Volume: 97, Issue:6

    Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cidofovir; Cornea; Cytosine; Drug Evaluation, Preclinical; Organ Culture Techniques; Organophosphonates; Varicellovirus; Virus Cultivation

2016
Brincidofovir treatment of acyclovir-resistant disseminated varicella zoster virus infection in an immunocompromised host.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5

    Topics: Acyclovir; Adult; Antibiotic Prophylaxis; Antineoplastic Agents; Antiviral Agents; Cytosine; Drug Resistance, Viral; Drugs, Investigational; Female; Foscarnet; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Herpes Zoster; Herpesvirus 3, Human; Humans; Immunocompromised Host; Investigational New Drug Application; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Organophosphonates; Transplantation, Homologous; Valacyclovir; Valine

2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5

    Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load

2016
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:5

    Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles

2017
Recurrent Herpes Labialis in Adults: New Tricks for an Old Dog.
    Journal of drugs in dermatology : JDD, 2017, Mar-01, Volume: 16, Issue:3

    Topics: Acyclovir; Administration, Oral; Administration, Topical; Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Labialis; Herpesvirus 1, Human; Humans; Hyperthermia, Induced; Infusions, Parenteral; Organophosphonates; Recurrence; Stomatitis, Herpetic; Viral Load

2017
New modified 2-aminobenzimidazole nucleosides: Synthesis and evaluation of their activity against herpes simplex virus type 1.
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Acyclovir; Antiviral Agents; Benzimidazoles; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Humans; Nucleosides; Organophosphonates

2017
Apigenin, a novel candidate involving herb-drug interaction (HDI), interacts with organic anion transporter 1 (OAT1).
    Pharmacological reports : PR, 2017, Volume: 69, Issue:6

    Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Apigenin; Cell Survival; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Herb-Drug Interactions; Inhibitory Concentration 50; Kidney Diseases; Madin Darby Canine Kidney Cells; Male; Organic Anion Transport Protein 1; Organophosphonates; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Time Factors

2017
The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase.
    The Journal of infectious diseases, 2018, 02-14, Volume: 217, Issue:5

    Topics: Acyclovir; Amino Acid Substitution; Antiviral Agents; Cells, Cultured; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mutation, Missense; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Selection, Genetic; Sequence Analysis, DNA; Tenofovir; Viral Proteins

2018
An acyclic phosphonate prodrug of HPMPC is effective against VZV in skin organ culture and mice.
    Antiviral research, 2022, Volume: 199

    Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Herpesvirus 3, Human; Humans; Mice; Organ Culture Techniques; Organophosphonates; Prodrugs; Viral Regulatory and Accessory Proteins

2022