organophosphonates has been researched along with acid phosphatase in 21 studies
| Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) | Studies (acid phosphatase) | Trials (acid phosphatase) | Recent Studies (post-2010) (acid phosphatase) |
|---|---|---|---|---|---|
| 9,968 | 880 | 3,596 | 24,029 | 223 | 1,701 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (52.38) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Hickey, ME; van Etten, RL; Waymack, PP | 1 |
| Felix, R; Fleisch, H; Graham, R; Russell, G | 1 |
| Dahl, O; Dissing, J; Svensmark, O | 1 |
| Butler, LG; Kelly, SJ | 1 |
| Kozar, Z; Martynowicz, T; Seniuta, R; Zarzycki, J | 1 |
| Fleisch, H; Monod, A; Morgan, DB; Russel, RG | 1 |
| Dambacher, MA; Fleisch, H; Guncaga, J; Haas, HG; Lauffenburger, T; Lentner, C; Olah, AJ | 1 |
| Ntiforo, C; Stein, M | 1 |
| Hensley, GT; Holmes, RA; Isitman, AT; Lewis, JD; Schmitt, GH | 1 |
| Wieneke, AA; Woodin, AM | 1 |
| Averill, BA; Davis, JC; Lin, SS | 1 |
| Beers, SA; Demarest, K; Jordan, J; Loughney, DA; Malloy, E; Schwender, CF | 1 |
| Carswell, MC; Grant, BR; Plaxton, WC | 1 |
| LaCount, MW; Lebioda, L; Ortlund, E | 1 |
| Kachkovskii, GA; Kolodyazhnyi, OI; Kukhar, VP; Mischenko, IM; Sheiko, SY; Tanchuk, VY; Vovk, AI | 1 |
| Benvenuti, M; Cappelletti, E; Lentini, G; Leone, R; Mangani, S; Thaller, MC | 1 |
| Guddat, LW; Mak, JY; McGeary, RP; Schenk, G; Vella, P | 1 |
| Chang, S; Chang, SY; Jeong, IH; Kim, BT; Kim, J; Kim, MH; Kim, SH; Lee, MY | 1 |
| Hussein, WM; McGeary, RP; Mohd-Pahmi, SH; Schenk, G | 1 |
| Jadhav, A; Lea, WA; Maloney, DJ; McCoy, ES; Mott, BT; Simeonov, A; Zylka, MJ | 1 |
| Adibi, H; Feder, D; Guddat, LW; Hussein, WM; McGeary, RP; Mohd-Pahmi, SH; Schenk, G | 1 |
21 other study(ies) available for organophosphonates and acid phosphatase
| Article | Year |
|---|---|
pH-dependent leaving group effects on hydrolysis reactions of phosphate and phophonate esters catalyzed by wheat germ acid phosphatase.
Topics: Acid Phosphatase; Hydrogen-Ion Concentration; Kinetics; Mathematics; Organophosphonates; Organophosphorus Compounds; Seeds; Triticum | 1976 |
The effect of several diphosphonates on acid phosphohydrolases and other lysosomal enzymes.
Topics: Acid Phosphatase; Animals; Bone and Bones; Etidronic Acid; Female; Fetus; Kinetics; Liver; Lysosomes; Organophosphonates; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Rats | 1976 |
Phosphonic and arsonic acids as inhibitors of human red cell acid phosphatase and their use in affinity chromatography.
Topics: Acid Phosphatase; Arsanilic Acid; Arsenicals; Chemical Phenomena; Chemistry; Chromatography, Affinity; Chromatography, Agarose; Erythrocytes; Humans; Kinetics; Organophosphonates; Structure-Activity Relationship | 1979 |
Enzymic hydrolysis of phosphonate esters.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cations, Divalent; Cattle; Chickens; Escherichia coli; Esterases; Intestines; Isoelectric Focusing; Molecular Weight; Nitrophenols; Organ Specificity; Organophosphonates; Rabbits; Seeds; Species Specificity | 1975 |
Histochemical study of drug effects on mic infected with Trichinella spiralis.
Topics: Acetylcholinesterase; Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Anthelmintics; DNA; Glycogen; Histocytochemistry; Male; Mice; Muscles; Organophosphonates; Phosphotransferases; RNA; Succinate Dehydrogenase; Sulfhydryl Compounds; Thiabendazole; Trichinella; Trichinellosis | 1967 |
Influence of dichloromethylene diphosphonate (Cl2MDP) and calcitonin on bone resorption, lactate production and phosphatase and pyrophosphatase content of mouse calvaria treated with parathyroid hormone in vitro.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium Radioisotopes; Chlorine; Culture Techniques; Lactates; Methane; Mice; Organophosphonates; Parathyroid Hormone; Phosphoric Monoester Hydrolases; Pyrophosphatases; Skull | 1973 |
Diphosphonate treatment of Paget's disease of bone. A correlated metabolic, calcium kinetic and morphometric study.
Topics: Acid Phosphatase; Aged; Biopsy; Bone and Bones; Bone Resorption; Calcium; Calcium Radioisotopes; Ethanol; Female; Follow-Up Studies; Humans; Hydroxyproline; Kinetics; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Osteitis Deformans; Phosphorus; Time Factors | 1974 |
Organophosphorus compounds and carbamates as perilysosomal modifiers.
Topics: Acid Phosphatase; Animals; Carbamates; Cathepsins; Chromatography, Thin Layer; Hydrocortisone; Hydrogen-Ion Concentration; Liver; Lysosomes; Malathion; Male; Organophosphonates; Organophosphorus Compounds; Paraoxon; Rats; Sucrose; Sulfatases; Time Factors; Ultracentrifugation | 1974 |
A proposed mechanism for 99mTc-labeled polyphosphate and diphosphonate uptake by human breast tissue.
Topics: Acid Phosphatase; Animals; Bone and Bones; Breast Neoplasms; Female; Histocytochemistry; Humans; Lactation; Mammary Glands, Animal; Organophosphonates; Pregnancy; Radionuclide Imaging; Rats; Technetium | 1974 |
The action of phosphonates on the leucocyte in relation to the mode of action of leucocidin. The properties of the potassium pump and the inhibition of chemotaxis.
Topics: Acid Phosphatase; Animals; Biological Transport, Active; Calcium; Cell Biology; Cell Membrane; Chemotaxis; Glucuronidase; In Vitro Techniques; Isoflurophate; Leukocidins; Leukocytes; Nitrophenols; Organophosphonates; Phosphates; Potassium; Rabbits; Stimulation, Chemical | 1969 |
Kinetics and optical spectroscopic studies on the purple acid phosphatase from beef spleen.
Topics: Acid Phosphatase; Animals; Cattle; Fluorides; Kinetics; Organophosphonates; Organophosphorus Compounds; Phosphates; Spectrophotometry; Spleen | 1981 |
Phosphatase inhibitors--III. Benzylaminophosphonic acids as potent inhibitors of human prostatic acid phosphatase.
Topics: Acid Phosphatase; Benzyl Alcohols; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Male; Models, Molecular; Organophosphonates; Prostate; Protein Conformation | 1996 |
Disruption of the phosphate-starvation response of oilseed rape suspension cells by the fungicide phosphonate.
Topics: Acid Phosphatase; Adenine Nucleotides; Antifungal Agents; Biological Transport; Brassica; Cells, Cultured; Kinetics; Organophosphonates; Phosphates; Phosphofructokinase-1 | 1997 |
Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design.
Topics: Acid Phosphatase; Animals; Binding Sites; Carbohydrates; Catalysis; Crystallography, X-Ray; Dimerization; Enzyme Inhibitors; Humans; Macromolecular Substances; Male; Models, Chemical; Models, Molecular; Organophosphonates; Phosphates; Polyethylene Glycols; Protein Tyrosine Phosphatases; Rats; Semen | 2003 |
Stereoselectivity of binding of alpha-(N-benzylamino)benzylphosphonic acids to prostatic acid phosphatase.
Topics: Acid Phosphatase; Benzylamines; Chemistry, Pharmaceutical; Drug Design; Humans; Inhibitory Concentration 50; Male; Models, Chemical; Models, Molecular; Molecular Conformation; Organophosphonates; Prostate; Protease Inhibitors; Protein Binding; Protein Tyrosine Phosphatases; Stereoisomerism; Thermodynamics | 2008 |
Structural insights into the catalytic mechanism of the bacterial class B phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases.
Topics: Acid Phosphatase; Adenine; Aluminum Compounds; Aniline Compounds; Beryllium; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Fluorides; Hydrogen Bonding; Multigene Family; Organophosphonates; Organophosphorus Compounds; Protein Structure, Secondary; Substrate Specificity | 2008 |
Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids.
Topics: Acid Phosphatase; Bone Resorption; Enzyme Inhibitors; Glycoproteins; Humans; Naphthalenes; Organophosphonates; Osteoporosis | 2009 |
Synthesis and SAR of sulfonyl- and phosphoryl amidine compounds as anti-resorptive agents.
Topics: Acid Phosphatase; Amidines; Animals; Catalysis; Copper; Isoenzymes; Mice; Organophosphonates; Osteoclasts; Structure-Activity Relationship; Sulfones; Tartrate-Resistant Acid Phosphatase | 2010 |
Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase.
Topics: Acid Phosphatase; Animals; Binding, Competitive; Biological Assay; Catalytic Domain; Enzyme Inhibitors; Glycoproteins; Humans; Kinetics; Models, Biological; Molecular Structure; Organophosphonates; Plants; Swine | 2011 |
High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase.
Topics: Acid Phosphatase; Adenosine Monophosphate; Animals; Cattle; Computer Systems; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydrolysis; Inhibitory Concentration 50; Mice; Nucleotidases; Nucleotides, Cyclic; Organophosphonates; Protein Tyrosine Phosphatases; Reproducibility of Results; Small Molecule Libraries | 2013 |
Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches.
Topics: Acid Phosphatase; Animals; Glycoproteins; Humans; Mammals; Mice; Organophosphonates; Osteoporosis; Plants; Swine | 2023 |