Page last updated: 2024-09-05

organophosphonates and 9-(2-(phosphonomethoxy)ethyl)adenine diphosphate

organophosphonates has been researched along with 9-(2-(phosphonomethoxy)ethyl)adenine diphosphate in 4 studies

Compound Research Comparison

Studies
(organophosphonates)
Trials
(organophosphonates)
Recent Studies (post-2010)
(organophosphonates)
Studies
(9-(2-(phosphonomethoxy)ethyl)adenine diphosphate)
Trials
(9-(2-(phosphonomethoxy)ethyl)adenine diphosphate)
Recent Studies (post-2010) (9-(2-(phosphonomethoxy)ethyl)adenine diphosphate)
9,9688803,5961003

Protein Interaction Comparison

ProteinTaxonomyorganophosphonates (IC50)9-(2-(phosphonomethoxy)ethyl)adenine diphosphate (IC50)
Calmodulin-sensitive adenylate cyclaseBacillus anthracis0.036
Reverse transcriptase/RNaseH Human immunodeficiency virus 18.3

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Birkus, G; Holý, A; Otová, B; Votruba, I1
Erion, MD; Hong, Z; Lin, CC; Vitarella, D; Yeh, LT1
Fernández-Botello, A; Griesser, R; Holý, A; Moreno, V; Sigel, H1
Česnek, M; Dvoráková, A; Janeba, Z; Mertlíková-Kaiserová, H; Šmídková, M; Tloust'ová, E1

Other Studies

4 other study(ies) available for organophosphonates and 9-(2-(phosphonomethoxy)ethyl)adenine diphosphate

ArticleYear
9-[2-(Phosphonomethoxy)ethyl]adenine diphosphate (PMEApp) as a substrate toward replicative DNA polymerases alpha, delta, epsilon, and epsilon*.
    Biochemical pharmacology, 1999, Aug-01, Volume: 58, Issue:3

    Topics: Adenine; Animals; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; DNA Replication; DNA-Directed DNA Polymerase; Organophosphonates; Rats; Rats, Sprague-Dawley; Substrate Specificity

1999
Remofovir mesylate: a prodrug of PMEA with improved liver-targeting and safety in rats and monkeys.
    Antiviral chemistry & chemotherapy, 2004, Volume: 15, Issue:6

    Topics: Adenine; Animals; Antiviral Agents; Autoradiography; Carbon Radioisotopes; Dose-Response Relationship, Drug; Drug Delivery Systems; Haplorhini; Hepatitis B, Chronic; Kidney; Liver; Mesylates; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Species Specificity; Tissue Distribution

2004
Acid-base and metal-ion-binding properties of 9-[2-(2-phosphonoethoxy)ethyl]adenine (PEEA), a relative of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). An exercise on the quantification of isomeric complex equilibria in so
    Inorganic chemistry, 2005, Jul-11, Volume: 44, Issue:14

    Topics: Adenine; Antiviral Agents; Binding Sites; Cations; Chelating Agents; Hydrogen-Ion Concentration; Isomerism; Kinetics; Ligands; Metals; Organometallic Compounds; Organophosphonates; Protons

2005
Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Adenine; Adenylate Cyclase Toxin; Animals; Anti-Bacterial Agents; Bordetella pertussis; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Macrophages; Mice; Microbial Sensitivity Tests; Organophosphonates; Prodrugs

2014